Heparin sodium extracting solution concentrating device and concentrating and extracting method

Abstract

The invention relates to the technical field of extracting solution concentration devices, in particular to a heparin sodium extracting solution concentration device which comprises a concentration box and a filter hopper, an outward annular protrusion is arranged on the outer side of the filter hopper, an opening communicated with the external environment is formed in the upper end of the concentration box, and the heparin sodium extracting solution is concentrated through the annular protrusion on the outer side of the filter hopper. The upper end of the filter hopper is placed at the opening in the upper end of the concentration box, and a screw cap is arranged on the upper side of the filter hopper; through starting of a negative pressure device, negative pressure is generated on one side of a filtering mechanism, then water penetrates through the filtering mechanism, after filtering is completed, a cleaning mechanism is driven to move through a connecting frame, the cleaning mechanism cleans the filtering mechanism, and when the cleaning mechanism moves to the lowest end, a toothed plate makes contact with a gear and drives the gear to rotate, so that the filtering mechanism is cleaned. The two baffles are opened through rotation of the gear, the filtered and cleaned heparin sodium concentrate can fall into the precipitation barrel to be subjected to precipitation treatment in the next step, and the problem of blockage of the filtering mechanism is solved.

Description

Technical Field

[0001] This invention relates to the field of extract concentration equipment, specifically to a heparin sodium extract concentration equipment and concentration extraction method. Background Technology

[0002] For example, Chinese patent CN207987077U discloses a heparin sodium extract concentration device, which includes a primary processing tank and a secondary processing tank. A support block is fixedly provided between the primary processing tank and the secondary processing tank. A fixed cover is provided inside the primary processing tank. The fixed cover has dense through holes. A permeable membrane is provided on both sides of the fixed cover. The permeable membrane is fixedly connected to the inner wall of the primary processing tank. A vacuum layer is formed between the permeable membrane and the side wall of the primary processing tank. A feed pipe is fixedly provided at the center of the top of the primary processing tank.

[0003] The aforementioned patent uses a negative pressure device to create a vacuum within the vacuum layer, generating a strong negative pressure that allows water from the heparin sodium solution to pass through the permeation membrane into the vacuum, thereby initially increasing the concentration of the heparin sodium solution. However, the above solution has the following drawbacks: although this method can concentrate the heparin sodium extract, after concentration, some of the concentrate may adhere to the surface of the permeation membrane, causing membrane blockage. Furthermore, some of the concentrate may remain at the bottom of the primary processing tank, resulting in waste. Therefore, we have introduced a heparin sodium extract concentration device and concentration extraction method. Summary of the Invention

[0004] The purpose of this invention is to provide a heparin sodium extract concentration apparatus and concentration extraction method to solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the present invention provides the following technical solution:

[0006] A heparin sodium extract concentration device includes a concentration chamber and a filter bucket. The filter bucket has an outwardly pointing annular protrusion on its outer side. The upper end of the concentration chamber has an opening that communicates with the external environment. The filter bucket is positioned at the opening at the upper end of the concentration chamber through the annular protrusion on its outer side. A screw cap is provided on the upper side of the filter bucket and screwed into the opening at the upper end of the concentration chamber. Filtering mechanisms are provided on both sides of the filter bucket and connected to the inside of the concentration chamber. The filter bucket performs coarse filtration of the heparin sodium extract, and the filtering mechanisms perform fine filtration of the heparin sodium extract. One side of the filtering mechanism is in contact with a cleaning mechanism, which removes the filter material adhering to the surface of the filtering mechanism. The cleaning mechanism is connected to a sliding rod. One end of the sliding rod slides into a sliding groove, which is located inside the concentration chamber. The end of the sliding rod away from the sliding groove extends into a connecting cavity and is fixedly connected to a connecting frame. The connecting frame slides into the connecting cavity.

[0007] A support rod is slidably connected to the inner side of the connecting frame. Both ends of the support rod extend into the connecting cavity and are fixedly connected to the gear plate. A lifting mechanism is provided inside the support rod, which drives the support rod and the connecting frame to move. Two baffles are movably connected to the inner side of the concentration tank. One end of the baffle extends into the connecting cavity and is fixedly connected to the gear. A limiting mechanism is engaged on the outer side of the gear. The limiting mechanism is set inside the concentration tank and limits the gear. A movable installation mechanism is provided inside the concentration tank. Several sedimentation tanks are installed on the upper end of the movable installation mechanism, which drives the sedimentation tanks to move.

[0008] Both ends of the concentration tank are connected to extraction and storage mechanisms, with the lower end of the extraction and storage mechanism extending into the concentration tank. Both ends of the concentration tank are fixedly connected to negative pressure devices. The upper end of the screw cap is fixedly connected to a one-way valve. A liquid addition solenoid valve is fixedly connected to the outside of the concentration tank, with one end of the liquid addition solenoid valve extending into the inside of the concentration tank.

[0009] Preferably, the filtration mechanism includes one elastic filter membrane and two elastic membranes. The upper ends of the elastic filter membrane and the elastic membranes are fixedly connected to the lower end of the connecting block. The lower ends of the elastic filter membrane and the elastic membranes are fixedly connected to the inside of the concentration tank. The upper end and both sides of the connecting block are fixedly connected to the inside of the concentration tank. The side of the two elastic membranes away from the elastic filter membrane is fixedly connected to the inside of the concentration tank.

[0010] Preferably, the cleaning mechanism includes a connecting bucket, one side of which contacts a connecting block. Two T-shaped rods are fixedly connected to the side of the connecting bucket away from the connecting block. The T-shaped rods are movably connected to a slide rod. A connecting spring is sleeved on the outside of the T-shaped rod. One end of the connecting spring is fixedly connected to the connecting bucket, and the other end is fixedly connected to the slide rod. A first solenoid valve is fixedly connected to the upper end of the connecting bucket. The upper end of the first solenoid valve is fixedly connected to a spiral hose. The upper end of the spiral hose is fixedly connected to the output end of a blower. The blower is fixedly connected to the upper end of a concentration tank.

[0011] Preferably, the lifting mechanism includes a first lead screw, the support rod is screwed to the outside of the first lead screw, the upper end of the first lead screw is movably connected to the inside of the concentration tank, and the lower end is fixedly connected to the output end of the first motor, the first motor being fixedly connected inside the concentration tank.

[0012] Preferably, two guide rods are fixedly connected to the lower end of the support rod. The lower end of the guide rod passes through the connecting frame. A first spring is sleeved on the outside of the guide rod. One end of the first spring is fixedly connected to the support rod, and the other end is fixedly connected to the inside of the connecting frame. A stirring rod is movably connected to the inside of the sedimentation tank. The lower end of the stirring rod passes through the sedimentation tank and is fixedly connected to the second magnetic block. Two doors are movably connected to one side of the concentration tank. Two water storage tanks are opened inside the concentration tank. Two drain solenoid valves are fixedly connected to one side of the concentration tank. One end of the drain solenoid valve is connected to the water storage tank.

[0013] Preferably, the limiting mechanism includes a T-shaped limiting rod, the lower end of which is slidably connected to a sliding cavity, the sliding cavity being opened inside the concentration tank, and a support spring being fixedly connected inside the sliding cavity, the other end of which is fixedly connected to the T-shaped limiting rod.

[0014] Preferably, the movable installation mechanism includes a base plate, which is movably connected to the inside of the concentration tank. A second lead screw is movably connected inside the base plate. One end of the second lead screw passes through the base plate and is movably connected to the inside of the concentration tank, while the other end passes through the base plate and is fixedly connected to the output end of a drive motor. The drive motor is fixedly connected to the outside of the concentration tank. Several T-shaped cavities are formed at the upper end of the base plate. Clamping plates are slidably connected inside the T-shaped cavities. Two second springs are fixedly connected to one side of each clamping plate. The other end of each second spring is fixedly connected to the T-shaped cavity. A sedimentation tank is clamped between two clamping plates. A first magnetic block is provided between two clamping plates. The first magnetic block is fixedly connected to the output end of a second motor. The second motor is fixedly connected inside the base plate.

[0015] Preferably, the extraction and storage mechanism includes an L-shaped connecting column, which is movably connected to the concentration tank. The lower end of the L-shaped connecting column extends into the concentration tank, and the upper end is movably connected to the inner side of the mounting frame. The mounting frame is fixedly connected to the outer side of the concentration tank. A third lead screw is screwed into the L-shaped connecting column. The lower end of the third lead screw is movably connected to the outer side of the concentration tank, and the upper end is fixedly connected to the output end of the lifting motor. The lifting motor is fixedly connected to the upper end of the mounting frame.

[0016] Preferably, a telescopic hose is fixedly connected inside the L-shaped connecting column. The lower end of the telescopic hose passes through the L-shaped connecting column and is fixedly connected inside the floating plate. Several support legs are fixedly connected to the lower end of the floating plate. A T-shaped guide rod is fixedly connected to the upper end of the floating plate. The upper end of the T-shaped guide rod slides into a guide cavity. The guide cavity is opened inside the L-shaped connecting column. A laser ranging sensor is fixedly connected to the upper end of the guide cavity. The upper end of the telescopic hose passes through the L-shaped connecting column and is fixedly connected to the input end of the liquid pump. The liquid pump is fixedly connected to the outside of the concentration tank. The output end of the liquid pump extends into the storage tank. The storage tank is fixedly connected to the outside of the concentration tank.

[0017] Furthermore, to achieve the above objectives, the present invention also provides a concentration extraction method for use in the heparin sodium extract concentration apparatus described above, comprising:

[0018] S1. Open the screw cap and pour the heparin sodium extract into the filter hopper for coarse filtration. The negative pressure device creates negative pressure on one side of the filter mechanism in the concentration tank. The residual water in the heparin sodium extract flows into the water storage tank under the action of negative pressure. After a certain period of time, control the negative pressure device to return the concentration tank to the normal pressure state. The first motor will start and drive the first lead screw to rotate. The connecting frame will move with the support rod. When the connecting frame moves, it will drive the slide rod to move. The slide rod moves and drives the cleaning mechanism to move. The cleaning mechanism back-flushes and cleans the filter mechanism.

[0019] S2. When the cleaning mechanism moves to the bottom of the filter mechanism, the connecting frame will not move with the support rod as it continues to move. After the toothed plate comes into contact with the gear, it drives the gear to rotate. The gear then drives the baffle to move synchronously, which causes the two baffles to open downwards, allowing the heparin sodium extract to fall into the sedimentation tank below. After the liquid falls in, the connecting frame and support rod return to their initial positions. When the toothed plate moves upwards, the two baffles close again.

[0020] S3. Ethanol can be added to the corresponding sedimentation tank through the liquid addition solenoid valve. The movable installation mechanism moves the sedimentation tank containing heparin sodium extract and ethanol to the bottom of the extraction and storage mechanism. After the heparin sodium extract and ethanol are mixed and precipitated, the liquid on the top of the sediment in the sedimentation tank is extracted by the extraction and storage mechanism. After extraction, the sedimentation tank is taken out.

[0021] Compared with the prior art, the beneficial effects of the present invention are as follows: the heparin sodium extract is coarsely filtered through the filter bucket. By activating the negative pressure device, a negative pressure is generated on one side of the filter mechanism, allowing water to pass through the filter mechanism. After filtration is completed, the cleaning mechanism is moved by the connecting frame to clean the filter mechanism. When the cleaning mechanism moves to the bottom, the toothed plate contacts the gear and drives the gear to rotate. The rotation of the gear causes the two baffles to open, and the filtered and cleaned heparin sodium concentrate falls into the sedimentation tank for further sedimentation treatment, solving the problem of clogging of the filter mechanism. At the same time, the open baffles prevent the concentrated heparin sodium liquid from not completely falling into the sedimentation tank due to residue. Attached Figure Description

[0022] Figure 1 This is a cross-sectional structural diagram of the present invention.

[0023] Figure 2 For the present invention Figure 1 Enlarged structural diagram at point B.

[0024] Figure 3 This is a cross-sectional view of the connection cavity location of the present invention.

[0025] Figure 4 For the present invention Figure 3 Enlarged structural diagram at point A in the middle.

[0026] Figure 5 This is a cross-sectional structural diagram showing the connection relationship between the support rod and the connecting frame of the present invention.

[0027] Figure 6 This is a three-dimensional structural diagram illustrating the connection relationship between the connecting frame and the slide bar of the present invention.

[0028] Figure 7 This is a three-dimensional structural diagram illustrating the connection relationship between the support rod and the toothed plate of the present invention.

[0029] Figure 8 This is a three-dimensional cross-sectional view of the L-shaped connecting column of the present invention.

[0030] Figure 9 This is a schematic diagram of the three-dimensional cross-sectional structure of the base plate of the present invention.

[0031] Figure 10 This is a schematic diagram of the main structure of the present invention.

[0032] In the diagram: 1. Concentrator; 2. Storage tank; 3. Drive motor; 4. Second lead screw; 5. Base plate; 6. Clamping plate; 7. Sedimentation tank; 8. Float; 9. First motor; 10. Gear; 11. First lead screw; 12. Mounting bracket; 13. Connecting bracket; 14. Toothed plate; 15. Slide rod; 16. L-shaped connecting column; 17. One-way valve; 18. Cap; 19. Door; 20. Lifting motor; 21. Liquid addition solenoid valve; 22. First magnetic block; 23. Stirring rod; 24. Telescopic hose; 25. Negative pressure device; 26. Fan; 27. Connecting block; 28. Slide groove; 29. ​​Connecting cavity; 30. Elastic Filter membrane; 31. Filter bucket; 32. Water storage tank; 33. Baffle; 34. Third lead screw; 35. T-shaped cavity; 36. Second spring; 37. Second motor; 38. Elastic membrane; 39. Connecting bucket; 40. T-shaped rod; 41. Support rod; 42. First spring; 43. Guide rod; 44. Guide cavity; 45. Laser rangefinder sensor; 46. Support leg; 47. Sliding cavity; 48. Support spring; 49. T-shaped limit rod; 50. Spiral hose; 51. First solenoid valve; 52. Connecting spring; 53. Second magnetic block; 54. T-shaped guide rod; 55. Drain solenoid valve; 56. Pump. Detailed Implementation

[0033] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0034] Please see Figure 1-10 The present invention provides a technical solution:

[0035] Example 1:

[0036] A heparin sodium extract concentration device includes a concentration chamber 1 and a filter hopper 31. The filter hopper 31 has several filter holes on its outer side and an outward-facing annular protrusion on its outer side. The upper end of the concentration chamber 1 has an opening that communicates with the external environment. Through the annular protrusion on the outer side of the filter hopper 31, the upper end of the filter hopper 31 is placed at the opening at the upper end of the concentration chamber 1. The lower end of the filter hopper 31 is inserted into the inside of the concentration chamber 1. The annular protrusion on the outer side of the filter hopper 31 is limited at the opening at the upper end of the concentration chamber 1, so that the filter hopper 31 does not completely enter the inside of the concentration chamber 1. The upper side of the filter hopper 31 is provided with a screw cap 18, which is screwed into the opening at the upper end of the concentration chamber 1. After the filter hopper 31 is installed, the heparin sodium extract is poured into the filter hopper 31, and the screw cap 18 is screwed into the opening at the upper end of the concentration chamber 1 to press the filter hopper 31 tightly.

[0037] Filtering mechanisms are provided on both sides of the filter bucket 31. The filtering mechanisms are connected to the inside of the concentration tank 1. The filter bucket 31 performs coarse filtration of the heparin sodium extract, and the filtering mechanisms perform fine filtration of the heparin sodium extract. One side of the filtering mechanism is in contact with the cleaning mechanism, which removes the filter material adhering to the surface of the filtering mechanism. The cleaning mechanism is connected to the slide rod 15. One end of the slide rod 15 is slidably connected to the slide groove 28, which is located inside the concentration tank 1. The end of the slide rod 15 away from the slide groove 28 extends into the connecting cavity 29 and is fixedly connected to the connecting frame 13. The connecting frame 13 is slidably connected to the connecting cavity 29. The slide rod 15 is limited by one end of the slide rod 15 sliding to the slide groove 28.

[0038] A support rod 41 is slidably connected to the inner side of the connecting frame 13. The connecting frame 13 has a cavity in which the support rod 41 is slidably connected. Both ends of the support rod 41 extend into the connecting cavity 29 and are fixedly connected to the toothed plate 14. A lifting mechanism is provided inside the support rod 41. The lifting mechanism drives the support rod 41 and the connecting frame 13 to move. Two baffles 33 are movably connected to the inner side of the concentration tank 1. Both ends of the baffles 33 are tightly fitted to the inner wall of the concentration tank 1. In order to ensure the sealing during use, sealing strips can be connected around the outer side of the baffles 33 to ensure the sealing of the concentration tank 1 after the two baffles 33 are closed.

[0039] One end of the baffle 33 extends into the connecting cavity 29 and is fixedly connected to the gear 10. A limiting mechanism is engaged on the outside of the gear 10. The limiting mechanism is set in the concentration tank 1. The gear 10 is limited by the limiting mechanism so that the two baffles 33 will not open downward when the tooth plate 14 is not in contact with the gear 10. A movable installation mechanism is provided inside the concentration tank 1. Several sedimentation tanks 7 are installed on the upper end of the movable installation mechanism. The sedimentation tanks 7 are moved by the movable installation mechanism.

[0040] Both ends of the concentration tank 1 are connected to extraction and storage mechanisms, with the lower end of the extraction and storage mechanism extending into the concentration tank 1. Both ends of the concentration tank 1 are fixedly connected to negative pressure devices 25. During use, a vacuum pump of appropriate size and model can be selected for the negative pressure devices 25. The upper end of the screw cap 18 is fixedly connected to a one-way valve 17. The one-way valve 17 allows the gas in the concentration tank 1 to be discharged into the external environment, and the gas in the external environment will not enter the concentration tank 1 through the one-way valve 17. A liquid addition solenoid valve 21 is fixedly connected to the outside of the concentration tank 1. One end of the liquid addition solenoid valve 21 extends into the inside of the concentration tank 1. By connecting the external liquid supply device to the liquid addition solenoid valve 21, ethanol can enter the inside of the concentration tank 1 and finally fall into the sedimentation tank 7.

[0041] Example 2:

[0042] Based on Example 1, in order to

[0043] The filtration mechanism includes one elastic filter membrane 30 and two elastic membranes 38. The upper ends of the elastic filter membrane 30 and the elastic membrane 38 are fixedly connected to the lower end of the connecting block 27. The lower end of the connecting block 27 is inclined. When the connecting hopper 39 moves upward to this inclined position, the connecting hopper 39 will be guided to move outward. The lower ends of the elastic filter membrane 30 and the elastic membrane 38 are fixedly connected to the inside of the concentration tank 1. The upper end and both sides of the connecting block 27 are fixedly connected to the inside of the concentration tank 1. The side of the two elastic membranes 38 away from the elastic filter membrane 30 is fixedly connected to the inside of the concentration tank 1. The elastic filter membrane 30 is arranged on both sides of the elastic filter membrane 30. Between the elastic membranes 38, the arrangement of the connecting bucket 39 allows the connecting bucket 39 to push the elastic filter membrane 30 and the elastic membrane 38, causing the elastic filter membrane 30 and the elastic membrane 38 to bulge and deform. The outlet of the connecting bucket 39 can cover the elastic filter membrane 30. The elastic filter membrane 30 can be a filter membrane with a certain degree of elasticity, such as a flexible flat composite membrane composed of an ultra-thin separation layer and a flexible support layer. The negative pressure device 25 keeps one side of the elastic filter membrane 30 under low pressure, forming a transmembrane pressure difference, allowing the water in the heparin sodium extract to pass through the elastic filter membrane 30.

[0044] The cleaning mechanism includes a connecting bucket 39, one side of which contacts a connecting block 27. Two T-shaped rods 40 are fixedly connected to the side of the connecting bucket 39 away from the connecting block 27. The T-shaped rods 40 are movably connected within a slide rod 15. A connecting spring 52 is sleeved on the outside of each T-shaped rod 40. One end of the connecting spring 52 is fixedly connected to the connecting bucket 39, and the other end is fixedly connected to the slide rod 15. A first solenoid valve 51 is fixedly connected to the upper end of the connecting bucket 39. The upper end of the first solenoid valve 51 is fixedly connected to a spiral hose 50, and the upper end of the spiral hose 50 is fixedly connected to a fan. At the output end of the machine 26, the fan 26 is fixedly connected to the upper end of the concentration box 1. When the downward moving connecting bucket 39 moves to the position of the elastic filter membrane 30, the connecting bucket 39 will contact the surface of the elastic filter membrane 30 under the elastic force of the connecting spring 52. The air blown out of the connecting bucket 39 blows the heparin sodium adhering to the surface of the elastic filter membrane 30 off. At the same time, under the elastic force of the connecting spring 52, the connecting bucket 39 also pushes the elastic filter membrane 30 to deform to a certain extent, so that the heparin sodium adhering to the surface of the elastic filter membrane 30 can fall off.

[0045] The lifting mechanism includes a first lead screw 11, a support rod 41 screwed to the outside of the first lead screw 11, the upper end of the first lead screw 11 being movably connected to the inside of the concentration tank 1, and the lower end being fixedly connected to the output end of the first motor 9. The first motor 9 is fixedly connected inside the concentration tank 1. Two guide rods 43 are fixedly connected to the lower end of the support rod 41. The lower end of the guide rods 43 passes through the connecting frame 13. A first spring 42 is sleeved on the outside of the guide rods 43. One end of the first spring 42 is fixedly connected to the support rod 41, and the other end is fixedly connected to the inside of the connecting frame 13. A stirring rod 23 is movably connected to the inside of the sedimentation tank 7. The lower end of the stirring rod 23 passes through the sedimentation tank 7 and is fixedly connected to the second magnetic block 53. Two tank doors 19 are movably connected to one side of the concentration tank 1. Two water storage tanks 32 are opened inside the concentration tank 1. Two drain solenoid valves 55 are fixedly connected to one side of the concentration tank 1. One end of the drain solenoid valve 55 is connected to the water storage tank 32. By opening the drain solenoid valve 55, the water in the water storage tank 32 can be drained.

[0046] The limiting mechanism includes a T-shaped limiting rod 49. The lower end of the T-shaped limiting rod 49 is slidably connected to the sliding cavity 47, which is located inside the concentration tank 1. A support spring 48 is fixedly connected inside the sliding cavity 47. The other end of the support spring 48 is fixedly connected to the T-shaped limiting rod 49. The upper end of the T-shaped limiting rod 49 is tapered. The support spring 48 can be used with appropriate elasticity to ensure that after a certain amount of heparin sodium extract enters the inside of the concentration tank 1, one end of the T-shaped limiting rod 49 can also be engaged in the tooth groove of the gear 10.

[0047] The movable installation mechanism includes a base plate 5, which is movably connected to the inside of the concentration tank 1. A second lead screw 4 is movably connected inside the base plate 5. One end of the second lead screw 4 passes through the base plate 5 and is movably connected to the inside of the concentration tank 1, while the other end passes through the base plate 5 and is fixedly connected to the output end of the drive motor 3. The drive motor 3 is fixedly connected to the outside of the concentration tank 1. Several T-shaped cavities 35 are opened at the upper end of the base plate 5. Clamping plates 6 are slidably connected inside the T-shaped cavities 35. Two second springs 36 are fixedly connected to one side of the clamping plates 6, and the other end of the second springs 36 is fixedly connected to the T-shaped cavities 35. A sedimentation tank 7 is held between plates 6. A first magnetic block 22 is provided between the two clamping plates 6. The first magnetic block 22 is fixedly connected to the output end of the second motor 37. The second motor 37 is fixedly connected to the bottom plate 5. Pushing the two clamping plates 6 outward causes their lower ends to move along the T-shaped cavity 35. At this time, the second spring 36 is compressed, and the sedimentation tank 7 is placed between the two clamping plates 6. Releasing the push on the clamping plates 6 causes the two clamping plates 6 to clamp and limit the sedimentation tank 7 under the elastic force of the second spring 36. At the same time, the first magnetic block 22 and the second magnetic block 53 are attracted together.

[0048] The extraction and storage mechanism includes an L-shaped connecting column 16, which is movably connected to the concentration tank 1. The lower end of the L-shaped connecting column 16 extends into the concentration tank 1, and the upper end is movably connected to the inner side of the mounting frame 12. The mounting frame 12 has a sliding cavity, and one end of the L-shaped connecting column 16 slides into the sliding cavity. The mounting frame 12 is fixedly connected to the outside of the concentration tank 1. A third screw 34 is screwed into the L-shaped connecting column 16. The lower end of the third screw 34 is movably connected to the outside of the concentration tank 1, and the upper end is fixedly connected to the output end of the lifting motor 20. The lifting motor 20 is fixedly connected to the upper end of the mounting frame 12. A telescopic hose 24 is fixedly connected into the L-shaped connecting column 16. The lower end of the telescopic hose 24 passes through the L-shaped connecting column 16 and is fixedly connected to the floating plate 8. The lower end of the telescopic hose 24 passes through the floating plate 8. When the floating plate 8 moves, the telescopic hose 24 will also move to a certain extent.

[0049] Several support legs 46 are fixedly connected to the lower end of the floating plate 8, and a T-shaped guide rod 54 is fixedly connected to the upper end of the floating plate 8. The upper end of the T-shaped guide rod 54 slides into the guide cavity 44, which is opened in the L-shaped connecting column 16. A laser rangefinder 45 is fixedly connected to the upper end of the guide cavity 44. The laser rangefinder 45 can be selected with appropriate size and model during use. The upper end of the telescopic hose 24 passes through the L-shaped connecting column 16 and is fixedly connected to the input end of the liquid pump 56. The liquid pump 56 is fixedly connected to the outside of the concentration tank 1, and the output end of the liquid pump 56 extends into the storage tank 2. The storage tank 2 is fixedly connected to the outside of the concentration tank 1. The storage tank 2 is equipped with a valve. By opening the valve, the liquid in the storage tank 2 can be taken out for further concentration. A filter membrane can be installed at the input end of the blower 26 during use to ensure that the air entering the spiral hose 50 is free of impurities.

[0050] Furthermore, to achieve the above objectives, the present invention also provides a concentration extraction method for the above-mentioned heparin sodium extract concentration apparatus, comprising:

[0051] S1. Open the screw cap 18 and pour the heparin sodium extract into the filter hopper 31 for coarse filtration. The negative pressure device 25 creates a negative pressure on one side of the filter mechanism in the concentration tank 1. The residual water in the heparin sodium extract flows into the water storage tank 32 under the action of the negative pressure. After a certain period of time, control the negative pressure device 25 to return the concentration tank 1 to the normal pressure state. The first motor 9 will start and drive the first lead screw 11 to rotate. The connecting frame 13 will move with the support rod 41. When the connecting frame 13 moves, it will drive the slide rod 15 to move. The movement of the slide rod 15 will drive the cleaning mechanism to move. The cleaning mechanism will backflush the filter mechanism for cleaning.

[0052] S2. When the cleaning mechanism moves to the bottom of the filter mechanism, as the support rod 41 continues to move, the connecting frame 13 will not move with it. After the toothed plate 14 contacts the gear 10, it drives the gear 10 to rotate. The gear 10 then drives the baffle 33 to move synchronously, thereby causing the two baffles 33 to open downwards, allowing the heparin sodium extract to fall into the sedimentation tank 7 below. After falling in, the connecting frame 13 and the support rod 41 return to their initial positions. When the toothed plate 14 moves upwards, it causes the two baffles 33 to close again.

[0053] S3. Ethanol can be added to the corresponding sedimentation tank 7 through the liquid addition solenoid valve 21. The movable installation mechanism moves the sedimentation tank 7 containing heparin sodium extract and ethanol to the bottom of the extraction and storage mechanism. After the heparin sodium extract and ethanol are mixed and precipitated, the liquid on the top of the precipitate in the sedimentation tank is extracted by the extraction and storage mechanism. After extraction, the sedimentation tank is taken out.

[0054] Working principle: During use, open the screw cap 18 and pour the heparin sodium extract into the filter hopper 31 for coarse filtration. The filtered extract flows to the upper end of the two baffles 33. Some of the water in the heparin sodium extract will pass through the elastic filter membrane 30 and flow into the water storage tank 32. Open the negative pressure device 25 to create a negative pressure on the side of the elastic filter membrane 30 near the negative pressure device 25 in the concentration tank 1. At this time, the residual water in the heparin sodium extract passes through the elastic filter membrane 30 under the action of negative pressure and flows into the water storage tank 32. After a certain period of time, control the negative pressure device 25 to return the concentration tank 1 to the normal pressure state. At this time, the first motor 9 will start and drive the first lead screw 11 to start rotating. The rotation of the first lead screw 11 drives the support rod 41 to rotate synchronously. Under the elastic force of the first spring 42, the connecting frame 13 will move with the support rod 41. Connected to two sliding rods 15, the sliding rods 15 move when the connecting frame 13 moves. The movement of the sliding rods 15 causes the connecting bucket 39 to move downwards. The blower 26 starts and inputs air into the spiral hose 50. By opening the first solenoid valve 51, air can enter the connecting bucket 39. When the downward-moving connecting bucket 39 moves to the position of the elastic filter membrane 30, the connecting bucket 39 will contact the surface of the elastic filter membrane 30 under the elastic force of the connecting spring 52. The air blown out of the connecting bucket 39 blows off the heparin sodium adhering to the surface of the elastic filter membrane 30. At the same time, under the elastic force of the connecting spring 52, the connecting bucket 39 also pushes the elastic filter membrane 30 to deform to a certain extent, so that the heparin sodium adhering to the surface of the elastic filter membrane 30 can fall off. The gas entering the concentration box 1 will be discharged into the external environment through the one-way valve 17.

[0055] When the connecting bucket 39 moves to the bottom of the elastic filter membrane 30, the lower end of the connecting bucket 39 contacts the inside of the concentration tank 1. At this time, as the support rod 41 continues to move, the connecting frame 13 will not move. Driven by the first screw 11, the support rod 41 moves along the inside of the connecting frame 13. At this time, the first spring 42 is compressed. When the toothed plate 14 contacts the gear 10, the movement of the toothed plate 14 will drive the gear 10 to rotate clockwise. The gear 10 will then drive the baffle 33 to move synchronously, thereby causing the two baffles 33 to open downwards, allowing the heparin sodium extract to fall into the sedimentation tank 7 below. After the liquid falls in, the first motor 9 drives the first screw 11 to rotate in the opposite direction. At this time, the connecting frame 13 and the support rod 41 return to their initial positions. The blower 26 and the first solenoid valve 51 close. When the toothed plate 14 moves upwards, it causes the two baffles 33 to close again.

[0056] During the rotation of gear 10, the T-shaped limiting rod 49, which is engaged in the tooth groove of gear 10, will be squeezed and moved into the sliding cavity 47. At this time, the support spring 48 is compressed. When the other tooth groove on the outside of gear 10 rotates to the position of the T-shaped limiting rod 49, under the elastic force of the support spring 48, one end of the T-shaped limiting rod 49 will be inserted into the tooth groove, so that gear 10 is limited and the two baffles 33 will not open after the tooth plate 14 is disengaged from gear 10.

[0057] Ethanol can be added to the corresponding sedimentation tank 7 by means of the liquid addition solenoid valve 21. After the addition is completed, the liquid addition solenoid valve 21 is closed, the drive motor 3 is started and drives the second lead screw 4 to rotate. The second lead screw 4 drives the bottom plate 5 to move, so that the sedimentation tank 7 containing heparin sodium extract and ethanol is moved to the bottom of the floating plate 8. At the same time, the new sedimentation tank 7 will move to the bottom of the two baffles 33. The new sedimentation tank 7 can hold the next round of concentrated heparin sodium extract.

[0058] By turning on the second motor 37, the first magnetic block 22 connected to the output end is rotated. The first magnetic block 22 drives the second magnetic block 53 to rotate, which in turn drives the stirring rod 23 to rotate, stirring and mixing the heparin sodium extract and ethanol, thereby initially increasing the concentration of the heparin sodium solution. After mixing is complete, the second motor 37 is turned off. After the heparin sodium has precipitated, the lifting motor 20 is turned on, causing the third lead screw 34 to start rotating. The rotation of the third lead screw 34 causes the L-shaped connecting column 16 to move downward. When the float 8 moves to the upper surface of the solution, the float 8 will float on the surface of the solution. At this time, as the L-shaped connecting column 16 continues to move downward, the T-shaped guide rod 54 will move along the guide cavity 44. When the laser ranging sensor 45 detects the movement of the upper end of the T-shaped guide rod 54, it controls... The pump 56 is started, and the upper solution is drawn into the telescopic hose 24. The extracted solution is stored in the storage tank 2. Through the laser range sensor 45 and the floating plate 8, the moving speed of the L-shaped connecting column 16 is equal to the falling speed of the solution. When the support leg 46 at the lower end of the floating plate 8 moves to the upper end of the heparin sodium precipitate, the floating plate 8 will stop moving. After the laser range sensor 45 detects that the distance between it and the upper end of the T-shaped guide rod 54 has reached a certain set value, the pump 56 is turned off. At the same time, the output end of the lifting motor 20 will rotate in the opposite direction, so that the L-shaped connecting column 16 returns to the initial position. At this time, the operator can open the box door 19 to take out the precipitate tank 7 containing the concentrated heparin sodium solution and take out the filter hopper 31.

[0059] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A heparin sodium extract concentration device, comprising a concentration chamber and a filter bucket, wherein the filter bucket has an outwardly pointing annular protrusion on its outer side, characterized in that: The concentration chamber has an opening at the top that connects to the external environment. The filter bucket is positioned at the opening through an annular protrusion on its outer side. A screw cap is screwed onto the top of the filter bucket and into the opening. Filtering mechanisms are located on both sides of the filter bucket and connected to the inside of the concentration chamber. The filter bucket performs coarse filtration of the heparin sodium extract, while the filtering mechanisms perform fine filtration. One side of each filtering mechanism is in contact with a cleaning mechanism, which removes filter material adhering to its surface. The cleaning mechanism is connected to a sliding rod, one end of which slides into a groove located inside the concentration chamber. The end of the sliding rod away from the groove extends into a connecting cavity and is fixedly connected to a connecting frame, which slides into the connecting cavity. A support rod is slidably connected to the inner side of the connecting frame. Both ends of the support rod extend into the connecting cavity and are fixedly connected to the gear plate. A lifting mechanism is provided inside the support rod, which drives the support rod and the connecting frame to move. Two baffles are movably connected to the inner side of the concentration tank. One end of the baffle extends into the connecting cavity and is fixedly connected to the gear. A limiting mechanism is engaged on the outer side of the gear. The limiting mechanism is set inside the concentration tank and limits the gear. A movable installation mechanism is provided inside the concentration tank. Several sedimentation tanks are installed on the upper end of the movable installation mechanism, which drives the sedimentation tanks to move. Both ends of the concentration tank are connected to extraction and storage mechanisms, with the lower end of the extraction and storage mechanism extending into the concentration tank. Both ends of the concentration tank are fixedly connected to negative pressure devices. The upper end of the screw cap is fixedly connected to a one-way valve. A liquid addition solenoid valve is fixedly connected to the outside of the concentration tank, with one end of the liquid addition solenoid valve extending into the inside of the concentration tank.

2. The heparin sodium extract concentration apparatus according to claim 1, characterized in that: The filtration mechanism includes one elastic filter membrane and two elastic membranes. The upper ends of the elastic filter membrane and the elastic membranes are fixedly connected to the lower end of the connecting block. The lower ends of the elastic filter membrane and the elastic membranes are fixedly connected to the inside of the concentration tank. The upper end and both sides of the connecting block are fixedly connected to the inside of the concentration tank. The side of the two elastic membranes away from the elastic filter membrane is fixedly connected to the inside of the concentration tank.

3. The heparin sodium extract concentration apparatus according to claim 2, characterized in that: The cleaning mechanism includes a connecting bucket, one side of which contacts a connecting block. Two T-shaped rods are fixedly connected to the side of the connecting bucket away from the connecting block. The T-shaped rods are movably connected inside a sliding rod. A connecting spring is sleeved on the outside of the T-shaped rod. One end of the connecting spring is fixedly connected to the connecting bucket, and the other end is fixedly connected to the sliding rod. A first solenoid valve is fixedly connected to the upper end of the connecting bucket. The upper end of the first solenoid valve is fixedly connected to a spiral hose. The upper end of the spiral hose is fixedly connected to the output end of a blower. The blower is fixedly connected to the upper end of a concentration tank.

4. The heparin sodium extract concentration apparatus according to claim 1, characterized in that: The lifting mechanism includes a first lead screw, and a support rod is screwed to the outside of the first lead screw. The upper end of the first lead screw is movably connected to the inside of the concentration tank, and the lower end is fixedly connected to the output end of the first motor. The first motor is fixedly connected inside the concentration tank.

5. The heparin sodium extract concentration apparatus according to claim 1, characterized in that: Two guide rods are fixedly connected to the lower end of the support rod. The lower end of the guide rod passes through the connecting frame. A first spring is sleeved on the outside of the guide rod. One end of the first spring is fixedly connected to the support rod, and the other end is fixedly connected to the inside of the connecting frame. A stirring rod is movably connected to the inside of the sedimentation tank. The lower end of the stirring rod passes through the sedimentation tank and is fixedly connected to the second magnetic block. Two doors are movably connected to one side of the concentration tank. Two water storage tanks are opened inside the concentration tank. Two drain solenoid valves are fixedly connected to one side of the concentration tank. One end of the drain solenoid valve is connected to the water storage tank.

6. The heparin sodium extract concentration apparatus according to claim 1, characterized in that: The limiting mechanism includes a T-shaped limiting rod, the lower end of which is slidably connected to a sliding cavity. The sliding cavity is located inside the concentration tank, and a support spring is fixedly connected inside the sliding cavity. The other end of the support spring is fixedly connected to the T-shaped limiting rod.

7. The heparin sodium extract concentration apparatus according to claim 1, characterized in that: The movable installation mechanism includes a base plate, which is movably connected to the inside of the concentration tank. A second lead screw is movably connected inside the base plate. One end of the second lead screw passes through the base plate and is movably connected to the inside of the concentration tank, while the other end passes through the base plate and is fixedly connected to the output end of a drive motor. The drive motor is fixedly connected to the outside of the concentration tank. Several T-shaped cavities are formed at the upper end of the base plate. Clamping plates are slidably connected inside the T-shaped cavities. Two second springs are fixedly connected to one side of each clamping plate. The other end of each second spring is fixedly connected to the T-shaped cavity. A sedimentation tank is clamped between two clamping plates. A first magnetic block is provided between two clamping plates. The first magnetic block is fixedly connected to the output end of a second motor. The second motor is fixedly connected inside the base plate.

8. The heparin sodium extract concentration apparatus according to claim 1, characterized in that: The extraction and storage mechanism includes an L-shaped connecting column, which is movably connected to the concentration tank. The lower end of the L-shaped connecting column extends into the concentration tank, and the upper end is movably connected to the inner side of the mounting frame. The mounting frame is fixedly connected to the outer side of the concentration tank. A third lead screw is screwed into the L-shaped connecting column. The lower end of the third lead screw is movably connected to the outer side of the concentration tank, and the upper end is fixedly connected to the output end of the lifting motor. The lifting motor is fixedly connected to the upper end of the mounting frame.

9. The heparin sodium extract concentration apparatus according to claim 8, characterized in that: A telescopic hose is fixedly connected inside the L-shaped connecting column. The lower end of the telescopic hose passes through the L-shaped connecting column and is fixedly connected inside the floating plate. Several support legs are fixedly connected to the lower end of the floating plate. A T-shaped guide rod is fixedly connected to the upper end of the floating plate. The upper end of the T-shaped guide rod slides into a guide cavity. The guide cavity is opened inside the L-shaped connecting column. A laser rangefinder sensor is fixedly connected to the upper end of the guide cavity. The upper end of the telescopic hose passes through the L-shaped connecting column and is fixedly connected to the input end of the liquid pump. The liquid pump is fixedly connected to the outside of the concentration tank. The output end of the liquid pump extends into the storage tank. The storage tank is fixedly connected to the outside of the concentration tank.

10. A method for concentration and extraction, used in the heparin sodium extract concentration apparatus according to any one of claims 1-9, characterized in that, include: S1. Open the screw cap and pour the heparin sodium extract into the filter hopper for coarse filtration. The negative pressure device creates negative pressure on one side of the filter mechanism in the concentration tank. The residual water in the heparin sodium extract flows into the water storage tank under the action of negative pressure. After a certain period of time, control the negative pressure device to return the concentration tank to the normal pressure state. The first motor will start and drive the first lead screw to rotate. The connecting frame will move with the support rod. When the connecting frame moves, it will drive the slide rod to move. The slide rod moves and drives the cleaning mechanism to move. The cleaning mechanism back-flushes and cleans the filter mechanism. S2. When the cleaning mechanism moves to the bottom of the filter mechanism, the connecting frame will not move with the support rod as it continues to move. After the toothed plate comes into contact with the gear, it drives the gear to rotate. The gear then drives the baffle to move synchronously, which causes the two baffles to open downwards, allowing the heparin sodium extract to fall into the sedimentation tank below. After the liquid falls in, the connecting frame and support rod return to their initial positions. When the toothed plate moves upwards, the two baffles close again. S3. Ethanol can be added to the corresponding sedimentation tank through the liquid addition solenoid valve. The movable installation mechanism moves the sedimentation tank containing heparin sodium extract and ethanol to the bottom of the extraction and storage mechanism. After the heparin sodium extract and ethanol are mixed and precipitated, the liquid on the top of the sediment in the sedimentation tank is extracted by the extraction and storage mechanism. After extraction, the sedimentation tank is taken out.

Images