Direction-convertible arterial drug delivery device based on rapid exchange balloon catheter

Abstract

The invention discloses a direction-convertible artery drug delivery device based on a rapid exchange balloon catheter, and belongs to the technical field of medical auxiliary devices.The device body comprises a catheter, a drug delivery chamber and a rapid exchange balloon assembly, the drug delivery chamber is arranged on the catheter, and the rapid exchange balloon assembly is arranged in the drug delivery chamber and the catheter; a guide wire pipeline is further arranged on the outer wall of the catheter; a plurality of side holes are formed in the side wall of the dosing chamber; a directional medicine outlet is formed in one end of the medicine feeding chamber; the quick exchange balloon assembly pumps gas or liquid into the balloon main body through the pressure pump so as to control the opening and closing of the directional medicine outlet; free switching between side hole local drug delivery and end hole far-end drug delivery is achieved on one catheter, and the clinical requirements of various drug delivery scenes in coronary artery interventional therapy can be better met.

Description

Technical Field

[0001] This invention relates to the field of medical assistive device technology, and more particularly to an arterial drug delivery device based on a rapidly exchangeable balloon catheter with reversible direction. Background Technology

[0002] During percutaneous coronary intervention (PCI), coronary thrombosis, local coronary artery spasm, and microvascular bed occlusion leading to no-reflow are frequently encountered. In such cases, intracoronary drug administration is necessary. Currently, the common method involves exchanging a microcatheter to the lesion site or distal to the coronary artery and then using a syringe to push the medication. However, existing methods have the following drawbacks:

[0003] (1) Microcatheters can only deliver drugs to the distal end of blood vessels, which cannot meet the need for drugs to remain in the thrombus to exert thrombolytic effects when coronary thrombosis occurs. Often, the thrombus in the coronary artery is not dissolved, so multiple injections of thrombolytic drugs are required, resulting in too much drug entering the blood circulation. This not only fails to achieve intracoronary thrombolysis, but also increases the risk of systemic bleeding.

[0004] (2) Microcatheter exchange requires the removal of the guidewire and the compression of the balloon in the guide catheter, which is complicated, increases the operation time, increases the use of consumables, and increases the economic burden (the current market price of microcatheters is 3,000-6,000 yuan). Summary of the Invention

[0005] The present invention aims to provide a reversible arterial drug delivery device based on a rapid exchange balloon catheter to solve the problems mentioned in the background art.

[0006] To achieve the above objectives, the present invention provides the following technical solution:

[0007] A reversible arterial drug delivery device based on a rapid exchange balloon catheter includes a catheter, a drug delivery chamber, and a rapid exchange balloon assembly. The drug delivery chamber is disposed on the catheter, and the rapid exchange balloon assembly is disposed inside the drug delivery chamber and the catheter. A guidewire is also disposed on the outer wall of the catheter.

[0008] Furthermore, the catheter is a double-layered tube, the innermost tubing of the catheter is the inner tubing, the inner tubing is a conventional coronary artery surgery catheter tubing, the interlayered tubing connects to the drug delivery chamber, and the interlayered tubing has a drug delivery port located away from the drug delivery chamber;

[0009] Furthermore, the guidewire is disposed on the outer wall of the catheter, and a guidewire inlet is provided near the drug delivery port.

[0010] Furthermore, the drug delivery chamber has several side holes on its side wall, and a directional drug outlet is provided at one end of the drug delivery chamber. The opening and closing of the directional drug outlet is controlled by the rapid exchange balloon assembly.

[0011] Furthermore, the rapid exchange balloon assembly includes a balloon body, a pressure pump, and a control tube. The balloon body is disposed in the drug delivery chamber near the directional drug outlet. The control tube is connected to the balloon body via the inner tubing of the catheter. The pressure pump is connected to the end of the control tube away from the balloon body and pumps gas or liquid into the balloon body through the pressure pump.

[0012] Compared with the prior art, the present invention has the following beneficial effects:

[0013] (1) The present invention designs side holes and directional drug outlets on the drug delivery chamber, and uses an airbag to open and close the directional drug outlets. The drug is diffused out from the side holes and makes large-area uniform contact with the thrombus, exerting local thrombolysis or relieving spasm. When the airbag contracts, the drug flows out from the directional drug outlets to the distal end, dilating the distal microvessels, thereby dilating the distal vascular bed and improving no-reflow.

[0014] (2) The catheter is mounted on the rapid exchange balloon system. The existing guidewire track can be used to insert the drug delivery catheter, which is convenient, fast, safe and economical.

[0015] (3) The drug delivery device designed in this invention can switch between local drug delivery and distal drug delivery, which can better meet the clinical needs of various drug delivery scenarios in coronary intervention. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of a reversible arterial drug delivery device based on a rapid-exchange balloon catheter;

[0017] Figure 2 This is a schematic diagram of the internal structure of an arterial drug delivery device based on a rapidly exchangeable balloon catheter with reversible direction.

[0018] The reference numerals in the accompanying drawings include:

[0019] 1. Catheter; 101. Inner tubing; 102. Interlayer tubing; 103. Drug delivery port; 104. Guidewire inlet; 2. Drug delivery chamber; 201. Side hole; 202. Directional drug delivery port; 3. Rapid exchange balloon assembly; 301. Balloon body; 302. Pressure pump; 303. Control tubing; 4. Guidewire tubing. Detailed Implementation

[0020] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments:

[0021] like Figure 1-2As shown, this invention provides a reversible arterial drug delivery device based on a rapid exchange balloon catheter. The main body of the device includes a catheter 1, a drug delivery chamber 2, and a rapid exchange balloon assembly 3. The drug delivery chamber 2 is disposed on the catheter 1, and the rapid exchange balloon assembly 3 is disposed inside the drug delivery chamber 2 and the catheter 1. At the same time, a guidewire 4 is also disposed on the outer wall of the catheter 1.

[0022] The catheter 1 is a double-layered tube. The inner tubing 101 is a standard coronary artery surgery catheter. The interlayer tubing 102 connects to the drug delivery chamber 2. A drug delivery port 103 is provided on the interlayer tubing 102 away from the drug delivery chamber 2. Medical personnel inject drugs through the drug delivery port 103, which then flows to the drug delivery chamber 2 through the interlayer tubing 102. The guidewire tubing 4 is located on the outer wall of the catheter 1. A guidewire inlet 104 is provided near the drug delivery port 103. This satisfies the working conditions of the guidewire without hindering the drug delivery.

[0023] The drug delivery chamber 2 has several side holes 201 on its side wall. After the drug delivery chamber 2 is filled with drug, the drug will spill out from the side holes 201 and make uniform contact with the thrombus over a large area, so as to exert local thrombolysis or relieve spasm. A directional drug outlet 202 is provided at one end of the drug delivery chamber 2. The opening and closing of the directional drug outlet 202 is controlled by the rapid exchange balloon assembly 3. When the directional drug outlet 202 is open, the drug will flow out from the directional drug outlet 202 to the distal end, dilating the distal microvessels.

[0024] The rapid exchange balloon assembly 3 includes a balloon body 301, a pressure pump 302, and a control tube 303. The balloon body 301 is disposed in the drug delivery chamber 2, near the directional drug delivery port 202. The control tube 303 is connected to the balloon body 301 via the inner tubing 101 of the catheter 1. The pressure pump 302 is connected to the end of the control tube 303 away from the balloon body 301. Gas or liquid is pumped into the balloon body 301 by the pressure pump 302, thereby controlling the contraction or expansion of the balloon body 301, and thus controlling the opening and closing of the directional drug delivery port 202.

[0025] The above descriptions are merely embodiments of the present invention, and common knowledge such as specific technical solutions and / or characteristics are not described in detail here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the technical solutions of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications and improvements will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A convertible directional arterial drug delivery device based on a rapid exchange balloon catheter, characterized by: The device body comprises a catheter (1), a drug delivery chamber (2) and a rapid exchange balloon assembly (3), the drug delivery chamber (2) is arranged on the catheter (1), the rapid exchange balloon assembly (3) is arranged inside the drug delivery chamber (2) and the catheter (1), and a guide wire pipeline (4) is further arranged on the outer wall of the catheter (1).

2. The convertible directional arterial drug delivery device based on a rapid exchange balloon catheter of claim 1, wherein: The catheter (1) is a double-layer tube, the innermost pipeline of the catheter (1) is an inner pipeline (101), the inner pipeline (101) is a pipeline of a conventional coronary artery surgery catheter (1), a sandwiched pipeline (102) is communicated with the drug delivery chamber (2), and a drug delivery port (103) is arranged at the position, away from the drug delivery chamber (2), of the sandwiched pipeline (102).

3. The convertible directional arterial drug delivery device based on a rapid exchange balloon catheter of claim 1, wherein: The guide wire pipeline (4) is arranged on the outer wall of the catheter (1) and is provided with a guide wire inlet (104) near the drug delivery port (103).

4. The convertible directional arterial drug delivery device based on a rapid exchange balloon catheter of claim 1, wherein: A plurality of side holes (201) are formed in the side wall of the drug delivery chamber (2), and a directional drug outlet (202) is formed at one end of the drug delivery chamber (2), and the directional drug outlet (202) is controlled to be opened and closed by the rapid exchange balloon assembly (3).

5. The convertible directional arterial drug delivery device based on a rapid exchange balloon catheter of claim 1, wherein: The rapid exchange balloon assembly (3) comprises a balloon body (301), a pressure pump (302) and a control pipe (303), the balloon body (301) is arranged in the drug delivery chamber (2) and is close to the directional drug outlet (202), the control pipe (303) is communicated with the balloon body (301) through the inner pipeline (101) of the catheter (1), and the pressure pump (302) is connected to one end of the control pipe (303) away from the balloon body (301), and gas or liquid is pumped into the balloon body (301) through the pressure pump (302).

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