A natural acne-fighting soothing composition and methods of making and using the same

Abstract

The application discloses a kind of natural acne-removing soothing compositions and preparation method and application thereof, belong to daily chemical field.The composition comprises 1-3 parts of natural emulsifier, 2-5 parts of emulsifying aid, 0.1-0.8 parts of oil control antibacterial agent, 0.5-2 parts of composite essential oil, 0.1-0.8 parts of soothing agent and 1-2 parts of deionized water by weight;Wherein natural emulsifier is the mixture of sucrose stearate and polyglycerol-10 laurate, emulsifying aid is 1,3-propanediol, oil control antibacterial agent is one or compound of persicin and magnolia officinalis extract, composite essential oil is the mixture of wild chrysanthemum, lavender and orchid grass essential oil, soothing agent is the compound of stearyl glycyrrhizinate and asiaticoside extract.The application also discloses the preparation method of the composition, and the microemulsion prepared by the application is natural, mild, has excellent extreme environmental stability, has antibacterial and anti-inflammatory and soothing repair functions, has good transdermal absorption, can effectively improve acne, and is suitable for the preparation of functional skin care products.

Description

Technical Field

[0001] This invention relates to the field of daily chemical products, and in particular to a natural acne-removing and soothing composition, its preparation method, and its application. Background Technology

[0002] Acne is a common skin problem, mainly manifested as pimples, papules, pustules, nodules, and cysts. Its occurrence is closely related to factors such as excessive sebum secretion, blockage of the pilosebaceous duct, and bacterial infection. Most acne, especially papular, pustules, nodular, and cystic acne, easily leaves scars, which seriously affects the patient's appearance and psychological state, negatively impacting work and life.

[0003] While current acne-fighting microemulsion compositions on the market can alleviate acne symptoms to some extent, they still have many drawbacks: First, they are highly irritating. Commonly used plant essential oils such as clove oil and thyme essential oil, as well as extracts such as shikonin and tanshinone II, while possessing antibacterial and anti-inflammatory effects, can easily cause skin redness, swelling, and allergies, and some dark-colored extracts can cause skin pigmentation. Second, they are highly dependent on surfactants. Traditional formulas contain high levels of surfactants and co-surfactants, which can easily cause dry skin and degreasing, making them unsuitable for long-term use. Third, they have insufficient transdermal absorption. Some ordinary emulsion-type compositions have only moderate transdermal absorption, significantly reducing their acne-fighting efficiency. Fourth, their efficacy is one-sided, focusing only on sterilization and anti-inflammation without providing deep conditioning for acne-prone skin, leading to recurring acne problems. Fifth, they have poor stability, easily separating under extreme environments such as high and low temperatures and alternating temperatures, affecting product quality.

[0004] Existing patented technologies also have significant shortcomings: the acne-removing microemulsion disclosed in Chinese patent CN115844792A uses a large amount of emulsifier and contains irritating essential oils such as clove oil and dark extracts, which can easily irritate the skin and cause pigmentation; the essential oil composition disclosed in Chinese patent CN118304225A is a common emulsion with poor transdermal absorption and limited acne-removing efficacy; the soothing acne-removing composition disclosed in Chinese patent CN118021674A uses hydroxy acids for acne removal, and although anti-allergy agents are added, it is still highly irritating to sensitive skin, and its acne-removing effect decreases significantly after dilution. Therefore, developing a natural acne-removing and soothing composition that combines low irritation, high stability, high transdermal absorption, and comprehensive conditioning effects has become an urgent problem to be solved in the industry.

[0005] Magnolia officinalis extract contains magnolol, an active ingredient with significant antibacterial, anti-inflammatory, and oil-controlling effects. It is also naturally sourced and highly safe. Prunol, as a natural antibacterial agent, exhibits strong inhibitory activity against Propionibacterium acnes and excellent permeability. The combination of these two ingredients enhances the oil-controlling and antibacterial effects while reducing the dosage of any single ingredient, thus improving the product's gentleness. Based on this, this invention optimizes the formulation and preparation process to develop a natural acne-reducing and soothing microemulsion composition with prunol-magnolia officinalis extract as the core oil-controlling and antibacterial system, addressing the pain points of existing products. Summary of the Invention

[0006] Addressing the core issues of existing acne-removing microemulsion compositions, such as strong irritation, high surfactant dependence, insufficient transdermal absorption, and poor stability, this invention provides a natural acne-removing and soothing composition and its preparation method by optimizing the formulation components and ratios, achieving both highly effective acne removal and gentle skincare performance.

[0007] To achieve the above objectives, the present invention adopts the following technical solution:

[0008] A natural acne-reducing and soothing composition, comprising, by weight, the following components:

[0009] 1-3 parts of natural emulsifier, wherein the natural emulsifier is a mixture of sucrose stearate and polyglycerol-10 laurate, and the weight ratio of sucrose stearate to polyglycerol-10 laurate is 1:0.5-1:2;

[0010] 2-5 parts of emulsifying aid, wherein the emulsifying aid is 1,3-propanediol;

[0011] 0.1-0.8 parts of oil-controlling antibacterial agent, wherein the oil-controlling antibacterial agent is one or a mixture of two of the following: tsaool and magnolia bark extract. When it is a mixture of two, the weight ratio of tsaool to magnolia bark extract is 1:1-1:3.

[0012] 0.5-2 parts of essential oil, wherein the essential oil is a mixture of wild chrysanthemum essential oil, lavender essential oil and vetiver essential oil, and the weight ratio of wild chrysanthemum essential oil, lavender essential oil and vetiver essential oil is 1:1:0.5 to 1:2:1;

[0013] The soothing agent is 0.1-0.8 parts, wherein the soothing agent is a compound of stearyl glycyrrhizate and Centella asiatica extract, and the weight ratio of stearyl glycyrrhizate to Centella asiatica extract is 1:0.2-1:1;

[0014] 1-2 parts of deionized water are used to make the composition ultimately transparent or translucent.

[0015] Preferably, the oil-controlling and antibacterial agent is a mixture of tau tannin and magnolia bark extract, with a weight ratio of 1:2.

[0016] Preferably, the magnolol content in the magnolol extract is not less than 90%, and the asiaticoside content in the centella asiatica extract is not less than 70%.

[0017] In addition, the present invention also discloses a method for preparing a natural acne-reducing and soothing composition, comprising the following steps:

[0018] Add the natural emulsifier, emulsifying aid, oil-controlling antibacterial agent and soothing agent to the reaction vessel, and keep warm at 70-75℃ and 30-50 rpm for 10-15 minutes until completely dissolved;

[0019] Cool the system to 45-48℃, add the essential oil, and continue stirring at the same stirring speed for 15-20 minutes until the system is homogeneous and transparent.

[0020] Preferably, after the heat preservation and dissolution in step (1), the temperature is reduced to 45-48°C at a rate of 1-2°C / minute.

[0021] The present invention also discloses an acne-removing and soothing microemulsion, which is prepared by mixing and stirring the above composition with 5-15 times its weight of deionized water. The microemulsion is translucent with a bluish tint or is transparent, with an average particle size of 10-50 nm; preferably, the average particle size of the microemulsion is 20-35 nm.

[0022] The present invention further discloses the application of the above composition or microemulsion, specifically as follows:

[0023] The composition or microemulsion can be used to prepare skin care products for the prevention or treatment of acne. The application method is to add the composition or microemulsion into the matrix in a certain proportion and then apply it to the affected skin.

[0024] The composition or microemulsion can be used to prepare functional cosmetics that soothe skin inflammation and repair the skin barrier. The application method is to mix the composition or microemulsion with a cosmetic matrix and then apply it topically daily.

[0025] The dosage form of the skin care product or functional cosmetic may be toner, serum, lotion or cream.

[0026] Compared with the prior art, the present invention provides a natural acne-removing and soothing composition and its preparation method, which has the following beneficial effects:

[0027] Natural safety: The composition of this invention does not contain highly irritating plant essential oils (such as clove oil and thyme essential oil) and dark extracts, thus avoiding the risk of causing skin redness and allergies and overcoming the disadvantages of high irritation in the prior art.

[0028] Low irritation: By optimizing the ratio and dosage of natural emulsifiers, emulsifying aids, oil-controlling antibacterial agents, essential oils and extracts, the irritation of the composition is significantly reduced, and the safety and applicability of the product are improved.

[0029] High stability: The microemulsion of the present invention remains stable at -15℃, 0℃, 50℃ and alternating temperature environments, and is not prone to separation, thus solving the problem of poor stability of existing emulsions under extreme environments.

[0030] Highly effective antibacterial and anti-inflammatory: Through the synergistic effect of natural oil-controlling antibacterial agents and essential oils, it achieves dual antibacterial activity against Staphylococcus aureus and Propionibacterium acnes, with an antibacterial rate of over 90%, significantly higher than the comparative emulsion.

[0031] Significant acne-removing effect: The microemulsion of this invention has significantly improved transdermal absorption efficiency, and has a significant acne-removing effect on symptoms such as pimples, papules, pustules, nodules, and cysts, with an effectiveness rate of 100% and a significant synergistic effect.

[0032] Skin-friendly: By optimizing the amount of surfactant, excessive degreasing and drying are avoided, making the product suitable for long-term use and overcoming the problem of skin discomfort caused by high surfactant dependence in traditional formulas.

[0033] Deeply addressing the symptoms: The composition of this invention not only has acne-removing function, but also achieves in-depth conditioning of acne-prone skin through the synergistic effect of multiple natural ingredients, effectively solving the problem that existing products only have a one-sided bactericidal and anti-inflammatory effect.

[0034] The process is simple: the preparation process does not require complicated equipment, the reaction conditions are mild (dissolving at 70-75℃ and dispersing and mixing at 45-48℃), the operation is simple, it is easy to carry out large-scale industrial production, and the production cost is controllable. Detailed Implementation

[0035] The technical solutions of the present invention will be clearly and completely described below with reference to the embodiments of the present invention. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the scope of protection of the present invention.

[0036] Magnolia officinalis extract is a natural active mixture extracted from the dried bark, root bark, and branch bark of plants in the Magnoliaceae family. It contains magnolol, an active ingredient, with a total content of no less than 90%. It has significant antibacterial, anti-inflammatory, and oil-controlling effects. It can inhibit the reproduction of pathogenic bacteria such as Propionibacterium acnes and Staphylococcus aureus, reduce skin inflammation, and regulate sebaceous gland secretion to reduce excessive oil secretion.

[0037] Prunol is a natural antibacterial active ingredient, mostly extracted from plants of the Myrtaceae family. It has two core characteristics: strong antibacterial properties and excellent transdermal absorption. It exhibits outstanding inhibitory activity against acne-causing bacteria such as Propionibacterium acnes and Staphylococcus aureus, and can penetrate deep into the hair follicles to exert its effects, blocking acne growth at its source.

[0038] Centella asiatica extract is an active ingredient extracted from the Centella asiatica plant (Apiaceae family). Its core active ingredient is asiaticoside, with a content of no less than 70%. It has dual effects of anti-inflammatory and soothing, and repairing the skin barrier. It can inhibit the release of inflammatory factors, relieve redness and stinging sensations in acne-prone skin, and promote collagen synthesis, accelerate the repair of damaged hair follicles and epidermal tissue, and improve acne marks and scars after acne healing.

[0039] Stearyl glycyrrhizate is a derivative of glycyrrhizic acid, belonging to the category of natural anti-inflammatory and soothing ingredients. It is highly skin-friendly and gentle, without causing irritation. Its core function is to target and inhibit skin inflammation, blocking the release of sensitizing substances such as histamine, and quickly relieving discomfort symptoms such as redness, swelling, and itching of acne. At the same time, it can regulate the skin's immune function, enhance the skin's resistance, and reduce the probability of recurrent inflammation.

[0040] Examples 1-3 are all based on the above-mentioned formulation range of the present invention to prepare natural acne-removing and soothing compositions. The core components include 1-3 parts of natural emulsifier, 2-5 parts of emulsifying aid, 0.1-0.8 parts of oil-controlling and antibacterial agent, 0.5-2 parts of compound essential oil, 0.1-0.8 parts of soothing agent and 1-2 parts of deionized water. The specific proportions are detailed in Table 1.

[0041] The specific dosage and ratio of each component are detailed in Table 1, which clearly demonstrates the rationality of the formulation range of this invention.

[0042] To verify the synergistic effect of the components and proportions in the formulation of this invention, comparative examples 1-5 were set up. These examples were designed with variables such as missing compound essential oil, single oil-controlling antibacterial agent, and replacement of emulsifying aid, and were compared with examples 1-3. The specific formulation composition is the same as in Table 1.

[0043] Table 1. Composition of the compositions in Examples 1-3 and Comparative Examples 1-5

[0044]

[0045] The compositions of Examples 1-3 and Comparative Examples 1-5 above were all prepared using a uniform process, the specific steps of which are as follows:

[0046] Add the natural emulsifier, emulsifying aid, oil-controlling antibacterial agent and soothing agent to the reaction vessel, and keep warm at 70-75℃ and 30-50 rpm for 10-15 minutes until completely dissolved;

[0047] Cool the system to 45-48℃, add essential oil (except for comparative examples 1-3, which do not require the addition of essential oil), and continue stirring at the same stirring speed for 15-20 minutes until the system is homogeneous and transparent (if a transparent system cannot be formed in the comparative examples, record it as milky white or cloudy).

[0048] The natural acne-removing and soothing compositions prepared in Examples 1-3 were each added to 9 times their weight of deionized water and stirred to dissolve, resulting in translucent bluish or transparent natural acne-removing and soothing microemulsions, which are referred to as Examples 4-6.

[0049] For the compositions of Examples 1-5, 9 times their weight of deionized water were added and stirred to dissolve, thus preparing comparative emulsions (referred to as Comparative Examples 6-10). Unlike the microemulsions of the Examples, Comparative Examples 6-9 formed translucent emulsions, while Comparative Example 10 exhibited a milky white turbid state without translucent bluish characteristics, and therefore did not belong to the category of microemulsions, further demonstrating the optimization effect of the formulation of the present invention on the system state.

[0050] Stability tests were conducted on the products of Examples 1-6 and Comparative Examples 5 and 10 prepared above, and the changes in appearance such as texture, color, and odor were evaluated. The test results are shown in Table 2.

[0051] Table 2. Product stability test results of Examples 1-6 and Comparative Examples 5 and 10

[0052]

[0053] Table 2 shows that the compositions and microemulsions of Examples 1-6 can maintain a transparent or semi-transparent bluish state under extreme environments such as -15℃ low temperature, 50℃ high temperature and alternating hot and cold conditions, and have excellent stability. However, the products of Comparative Examples 5 and 10 have significantly insufficient stability. They both show stratification under high temperature and alternating temperature conditions. Under low temperature conditions, some samples first become turbid and then separate into layers. This result fully verifies the key value of the synergistic effect of the components of this invention in improving the stability of the system.

[0054] Test subjects: Examples 4-8 (Examples 7 and 8 are replicates of Examples 4 and 6, used to verify repeatability), Comparative Examples 6-10;

[0055] Test method: Staphylococcus aureus and Propionibacterium acnes were used as test bacteria and bacterial suspensions were prepared. The bacterial suspensions were added to the corresponding samples and spread on the culture medium. After culturing for 48 hours, the bacterial suspensions were counted on the plates. The inhibition rate was calculated as (colony count of blank group - colony count of sample group) / colony count of blank group × 100%.

[0056] The strains were sourced from the Guangdong Institute of Microbiology: Staphylococcus aureus strain ATCC6538 and Propionibacterium acnes strain ATCC 11827.

[0057] Table 3. Antibacterial rate test results of Examples 4-8 and Comparative Examples 6-10

[0058]

[0059] Based on the data in Table 3, Example 4 exhibits the best antibacterial effect due to the synergistic effect of the compound oil-controlling antibacterial agent and the compound essential oil, achieving a 100% inhibition rate against both Staphylococcus aureus and Propionibacterium acnes. Examples 5-6, even using a single oil-controlling antibacterial agent, still demonstrate good antibacterial activity when combined with the compound essential oil, significantly outperforming the comparative examples. Comparative examples 6-8, lacking the compound essential oil, show an inhibition rate of 60%-80%, confirming the synergistic antibacterial effect of essential oil and oil-controlling antibacterial agent—the compound essential oil not only assists in antibacterial action but also promotes the penetration of antibacterial components, enhancing overall antibacterial efficacy. Comparative example 9, lacking an antibacterial agent, shows poor antibacterial effect relying solely on essential oil. Comparative example 10, due to the replacement of the emulsifying aid, suffers from system instability, resulting in uneven dispersion of antibacterial components and a significant reduction in utilization, further demonstrating the scientific validity and rationality of the formulation components and proportions of this invention.

[0060] (1) Experimental Objective and Basic Principle: Hyaluronidase is an important enzyme involved in human skin allergic reactions, and it can hydrolyze hyaluronic acid to reduce intercellular matrix adhesion. This experiment evaluates the soothing and anti-allergic effects of hyaluronidase by detecting the in vitro inhibitory effect of the sample on hyaluronidase. Hyaluronidase hydrolyzes hyaluronic acid to generate β-N-acetylglucosamine, which condenses with p-dimethylaminobenzaldehyde to produce a strong purple-red color. The absorbance at 590 nm is measured by an enzyme-linked immunosorbent assay (ELISA) reader, and the inhibition rate is calculated.

[0061] (2) Test items: Soothing effect in cosmetic efficacy evaluation (laboratory method): cosmetic-hyaluronidase inhibition test.

[0062] a. If the inhibition rate of the sample is greater than that of the negative control and P < 0.05, it is considered to have a significant soothing effect;

[0063] b. If the sample inhibition rate is ≤ the negative control inhibition rate or P ≥ 0.05, it is considered that there is no significant difference;

[0064] c. The IC50 of dipotassium glycyrrhizate is 2.75-3.25 mg / mL, and the experiment is valid.

[0065] 1) Reagents: Positive control: dipotassium glycyrrhizate; sodium acetate; glacial acetic acid; hyaluronidase; sodium hyaluronate; calcium chloride; sodium carbonate; p-dimethylaminobenzaldehyde;

[0066] 2) Instruments: electronic balance, microplate reader, pipette.

[0067] 3) Test product: Example 4 (optimal microemulsion) was selected as the test sample, with physiological saline as the negative control and dipotassium glycyrrhizate as the positive control to verify the synergistic effect of the soothing agent compound.

[0068] 4) Laboratory environment: temperature 25℃, relative humidity 50%, which meets the environmental requirements of the cosmetic efficacy evaluation test standard.

[0069] 5) Experimental Procedure:

[0070] a. Preparation before detection: Dissolve and dilute the positive control with water to prepare a series of concentration gradients of 3.50 mg / mL, 3.25 mg / mL, 3.00 mg / mL, 2.75 mg / mL, and 2.50 mg / mL to verify the test system and keep it ready for use;

[0071] b. Sample preparation: Weigh the sample and perform extraction pretreatment. (Use primary water as a negative control)

[0072] c. Measurement: Incubate 0.1 mL of calcium chloride solution and 0.5 mL of hyaluronidase solution at 37°C for 20 min; add 0.5 mL of sample diluent and continue incubation at 37°C for 20 min; add 0.5 mL of sodium hyaluronate solution and incubate at 37°C for 30 min, then let stand at room temperature for 5 min; add 0.1 mL of sodium carbonate solution and heat in a boiling water bath for 10 min, then immediately cool with ice water; add 1 mL of p-dimethylaminobenzaldehyde reagent, and finally dilute to 5 mL with glacial acetic acid. Let stand for 45 min for color development. Pipette 0.2 mL of each reaction solution into a 96-well microplate and measure the absorbance at 590 nm using a microplate reader. (Note: When the sample formulation does not contain hyaluronic acid, measurements in tubes E and F are not required.)

[0073] d. Calculation formula:

[0074]

[0075] in:

[0076] A – ABS value of control solution (hyaluronidase + deionized water + sodium hyaluronate)

[0077] B – ABS value of the control blank solution (buffer solution + deionized water + sodium hyaluronate)

[0078] C – ABS value of the sample solution (hyaluronidase + sample + sodium hyaluronate)

[0079] D – ABS value of blank sample solution (buffer solution + sample + sodium hyaluronate)

[0080] E – ABS value of the sample solution (hyaluronidase + sample + buffer solution)

[0081] F – ABS value of blank sample solution (buffer solution + sample + buffer solution)

[0082] Experimental results: The experimental results are shown in Table 4. There is a significant difference in the hyaluronidase inhibition rate between Example 4 and the control sample.

[0083] Table 4. Results of Soothing Performance Tests

[0084]

[0085] Experimental results show that, at 30% of the tested concentration, Example 4 exhibited a hyaluronidase inhibition rate of 60.2%, which was significantly lower than the negative control (P<0.05), demonstrating a significant soothing and anti-allergic effect. Its effect was close to that of the positive control, dipotassium glycyrrhizate. This result clearly proves that the combination of stearyl glycyrrhizate and Centella asiatica extract can produce a synergistic effect, effectively inhibiting hyaluronidase activity and reducing allergic reactions, which aligns with the design concept of this invention: gentle skincare suitable for sensitive acne-prone skin.

[0086] (1) Test samples: Microemulsion of Example 4, ordinary emulsion of Comparative Example 10 (ordinary emulsion in which glycerol is replaced with 1,3-propanediol).

[0087] (2) Test subjects: 135 people (60 with mild acne, 50 with moderate papules and pustules, and 25 with severe nodular cysts). The number of pimples and the degree of skin lesions on both sides of the face of the test subjects were similar.

[0088] (3) Usage method: After cleansing their face every morning and evening, testers should apply an appropriate amount of this product evenly to the affected area and gently massage until fully absorbed. The left side was treated with Example 4 and the right side with Comparative Example 10. One course of treatment lasted 7 days and 4 courses of treatment were observed.

[0089] (4) Evaluation criteria: Cured (skin lesions subside, inflammation disappears, acne marks fade), Significantly effective (most skin lesions subside, inflammation is reduced), Effective (skin lesions partially subside, inflammation is improved), Ineffective (skin lesions do not subside or increase);

[0090] Effectiveness rate = (number of cured + number of significantly effective + number of effective) / total number of people × 100%. The test results are shown in Table 5.

[0091] Table 5 Results of Acne Treatment Efficacy Test

[0092]

[0093] Results Analysis: The efficacy and cure rate of the microemulsion in Example 4 were significantly higher than those of the ordinary emulsion in Comparative Example 10 (ordinary emulsion in which glycerin replaces 1,3-propanediol). Specifically, the efficacy rate for mild acne reached 100% within 7 days, and the efficacy rate for moderate papules and pustules and severe nodular cysts reached 100% within 28 days. These results confirm that the microemulsion formulation of this invention can significantly improve the transdermal absorption efficiency of the active ingredients. Combined with the synergistic effect of each component, the acne-removing effect and onset speed are superior to traditional ordinary emulsions, further demonstrating the advantages of the microemulsion composition of this invention.

[0094] The above embodiments are several specific implementations of the present invention, intended to help understand the principles of the embodiments of the present invention. However, the implementation of the present invention is not limited to the above embodiments. At the same time, any modifications, equivalent substitutions or improvements made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A natural acne-reducing and soothing composition, characterized in that, By weight, it consists of the following components: 1-3 parts of natural emulsifier, wherein the natural emulsifier is a mixture of sucrose stearate and polyglycerol-10 laurate, and the weight ratio of sucrose stearate to polyglycerol-10 laurate is 1:0.5-1:2; 2-5 parts of emulsifying aid, wherein the emulsifying aid is 1,3-propanediol; 0.1-0.8 parts of oil-controlling antibacterial agent, wherein the oil-controlling antibacterial agent is one or a mixture of two of the following: tsaokool and magnolia bark extract, and the weight ratio of tsaokool to magnolia bark extract is 1:1-1:3 when the oil-controlling antibacterial agent is compounded. 0.5-2 parts of essential oil, wherein the essential oil is a mixture of wild chrysanthemum essential oil, lavender essential oil and vetiver essential oil, and the weight ratio of wild chrysanthemum essential oil, lavender essential oil and vetiver essential oil is 1:1:0.5 to 1:2:1; The soothing agent is 0.1-0.8 parts, wherein the soothing agent is a compound of stearyl glycyrrhizate and Centella asiatica extract, and the weight ratio of stearyl glycyrrhizate to Centella asiatica extract is 1:0.2-1:1; Add 1-2 parts of deionized water to make the final composition transparent or translucent.

2. The natural acne-reducing and soothing composition according to claim 1, characterized in that, The oil-controlling and antibacterial agent is a mixture of tau phenol and magnolia bark extract, with a weight ratio of 1:

2.

3. The natural acne-reducing and soothing composition according to claim 1, characterized in that, The content of magnolol in the Magnolia officinalis extract is not less than 90%, and the content of asiaticoside in the Centella asiatica extract is not less than 70%.

4. A soothing and acne-reducing microemulsion, characterized in that, The microemulsion is prepared by mixing and stirring the composition according to any one of claims 1-3 with 5-15 times its weight of deionized water. The microemulsion is translucent with a bluish tint or is transparent, with an average particle size of 10-50 nm.

5. The acne-reducing and soothing microemulsion according to claim 4, characterized in that, The average particle size of the microemulsion is 20-35 nm.

6. The application of any composition according to claims 1-3 or any microemulsion according to claims 4-5, characterized in that, This product is used to prepare skin care products that have the functions of preventing acne, soothing skin inflammation, and repairing the skin barrier. The product dosage form is toner, serum, lotion, or cream.

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