Sensitive skin suitable anti-inflammatory repair essence and preparation method thereof

Abstract

This invention relates to an anti-inflammatory and repairing serum suitable for sensitive skin and its preparation method. The main component of the serum is an active composition, which, by weight, comprises: 1.0-10.0 parts of brown algae extract, 0.5-5.0 parts of Centella asiatica extract, 0.1-2.0 parts of ceramide, and 0.05-1.0 parts of resveratrol liposomes. Through the synergistic effect of these four active ingredients, combined with specific liquid crystal emulsification and liposome encapsulation technologies, this invention significantly improves the bioavailability of the active substances, effectively improving symptoms of redness and spider veins in sensitive skin, repairing the skin's physical barrier function, and regulating skin microecological imbalance. It is suitable for daily care and barrier repair of sensitive skin.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, specifically to a repair composition that utilizes the synergistic effect of natural extracts and bioactive ingredients to repair the skin barrier, regulate the microecology, and improve rosacea. Background Technology

[0002] Sensitive skin is often characterized by a thinned stratum corneum and impaired skin barrier function, making it susceptible to inflammatory reactions (redness, burning, and visible blood vessels) from external stimuli. The formation mechanism of sensitive skin includes the following aspects: First, the skin barrier, composed of the "brick-and-mortar structure" of the stratum corneum and the tight connections of the granular layer, is a crucial foundation for the skin's physiological functions. Barrier damage is directly related to the occurrence of sensitive skin. Compared to normal skin, the barrier function of the stratum corneum in sensitive skin is weaker. When the number of keratinocytes decreases, leading to a thinner stratum corneum, percutaneous permeability increases, resulting in a higher reactivity of the skin to external stimuli. Furthermore, damage to the skin barrier is a key factor in the development of various skin diseases such as atopic dermatitis, acne, and psoriasis. Second, the skin can monitor and perceive environmental changes, such as temperature changes, humidity changes, and touch. These signals are transmitted to the nervous system through the release of neurotransmitters. Compared to non-sensitive skin, the stratum corneum of sensitive skin has a richer variety of nerves, and abnormal function directly leads to the occurrence of sensitive skin. Of the 200 known neurotransmitters, approximately 25 are found in the skin, such as substance P and calcitonin gene-related peptide (CGRP). Immune cell-mediated inflammatory responses are a significant factor in causing sensitive skin, damaging the skin barrier structure and nerve endings, leading to a vicious cycle. Third, the skin microbiome refers to the ecosystem composed of microorganisms such as bacteria, fungi, and viruses, and the microenvironment on the skin surface. Under physiological conditions, the skin's microbiota maintains a balance, playing beneficial roles in the body, such as clearing apoptotic cells, breaking down excess lipids, and resisting the invasion of external pathogens. When the skin microbiome is imbalanced, it can cause skin dysfunction, directly leading to skin sensitivity problems. Studies have shown that peptides with antibacterial effects help the skin resist the invasion of external pathogens and play an important role in maintaining the balance of the skin microbiome.

[0003] Existing repair products mostly focus on simple physical coverage or basic moisturizing, lacking comprehensive solutions that address multiple dimensions such as skin microecological balance and anti-oxidative stress. Common active ingredients in cosmetics suitable for sensitive skin can be divided into three main categories based on their mechanisms of action: first, repairing damaged skin barriers; second, regulating excessive neurovascular reactivity; and third, reducing immune inflammatory responses. Niacinamide, a chemically stable and water-soluble amide compound of nicotinic acid, repairs skin barrier function by improving keratinocyte differentiation and promoting the synthesis of ceramides, free fatty acids, and cholesterol. In addition, seaweed ingredients are commonly found in cosmetics suitable for sensitive skin, with Sargassum fusiforme extract from brown algae being the most representative. Studies have shown that Sargassum fusiforme extract can reduce pro-inflammatory cytokines released by mast cells and improve skin barrier function.

[0004] Existing technology CN112569151A employs an anti-allergic and barrier-repairing composition, comprising oligopeptide-1, Centella asiatica extract, Phoenix Dancong tea volatile oil, trans-4-tert-butylcyclohexanol, ceramide 2 liposomes, low molecular weight sodium hyaluronate, high molecular weight sodium hyaluronate, and urea, prepared through scientific formulation and specific processes, and used in skincare products. CN112826769A uses a composition of soy milk lactobacillus fermentation product filtrate, ceramide 3 liposomes, and Centella asiatica extract, achieving moisturizing and repairing effects by improving the balance of skin microbiota, replenishing the skin barrier, and reducing inflammatory responses. CN109549917A employs a skincare composition comprising skin conditioning agents, moisturizers, and plant-based complex anti-allergic agents, specifically including bitter orange fruit extract, rhubarb root extract, and Centella asiatica extract, etc., combined with hydroxyacetophenone, hyaluronic acid ceramide, ecoxib, etc., in the form of alcohol or water extracts to form an anti-allergic and soothing skincare product. However, there is a lack of in-depth research into brown algae extract and its combination with common sensitive skin ingredients such as Centella asiatica, ceramides, and resveratrol for the purpose of reducing redness and repairing sensitive skin. Summary of the Invention

[0005] The purpose of this invention is to overcome the shortcomings of the prior art and provide an anti-inflammatory and repairing serum suitable for sensitive skin and its preparation method.

[0006] To achieve the above objectives, the technical solution adopted by the present invention is as follows: In a first aspect, the present invention provides a composition comprising, by weight, the following active components: brown algae extract: 1.0-10.0 parts, centella asiatica extract: 0.5-5.0 parts, ceramide: 0.1-2.0 parts, and resveratrol liposomes: 0.05-1.0 parts.

[0007] Furthermore, the brown algae extract is at least one of the following: Fucus vesiculosus extract, giant kelp extract, or bubbly kelp extract, which are rich in brown algae polysaccharide sulfates, and the polysaccharide mass fraction is not less than 30%.

[0008] Furthermore, the Centella asiatica extract contains asiaticoside, hydroxyasiaticoside, asiatic acid, and hydroxyasiatic acid, wherein the total triterpenoid content is greater than 80% by mass.

[0009] Furthermore, the ceramide is selected from one or more of ceramide NP, ceramide AP, and ceramide EOP, and the ceramide is uniformly dispersed in the composition using liquid crystal emulsification technology.

[0010] Furthermore, the brown algae extract is Fucus dentata extract and / or Fucus buergerianum extract.

[0011] Furthermore, the composition further includes a matrix component comprising one or more of sodium hyaluronate, cetearyl glucoside, squalane, glycerin, xanthan gum, and 1,2-hexanediol.

[0012] Secondly, the present invention provides the application of the aforementioned composition in the preparation of topical skin repair products, said products being used to improve redness in sensitive skin, reduce inflammation and repair the physical barrier, and regulate skin microecological imbalance.

[0013] Furthermore, the product is described as an essence.

[0014] Thirdly, the present invention provides a method for preparing the aforementioned composition, characterized by comprising the following steps: S1. Oil phase preparation: Heat ceramide and oily components to 75-85℃ and stir until dissolved and homogeneous; S2. Aqueous phase preparation: Dissolve brown algae extract, centella asiatica extract and polyol in deionized water and heat to 75-85℃; S3. Emulsification: The oil phase is added to the aqueous phase for homogeneous emulsification to form a matrix system; S4. Addition of active substances: After the system cools down to 40-45℃, add the pre-treated resveratrol solution, stir evenly, and adjust the pH value to 5.5-6.5.

[0015] Fourthly, the present invention provides an essence product comprising the aforementioned composition.

[0016] Furthermore, the oily component is cholesterol or lecithin.

[0017] Compared with the prior art, the beneficial effects of the present invention are as follows: (1) Traditional ceramide repair only targets the filling of the skin's physical structure. However, if pathogenic bacteria (such as Staphylococcus aureus) proliferate excessively on the skin surface, they will continuously secrete proteases to decompose ceramides, resulting in poor repair effects. This invention has discovered that specific brown algae polysaccharides in brown algae extract can selectively promote the growth of Staphylococcus epidermidis (probiotics) and inhibit inflammatory bacteria (such as Staphylococcus aureus), thereby repairing sensitive skin through a dual homeostatic structure of physical and biological barriers.

[0018] (2) This invention constructs a composite water-retaining system by physical filling of ceramide and microecological metabolism induction of brown algae extract. Experiments show that its long-lasting water-retaining time can be extended to more than 24 hours, and the skin moisture content is still significantly higher than the control group after 3 days of discontinuation.

[0019] (3) Studies have shown that redness in sensitive skin is not only a problem of vasodilation, but is often accompanied by a hypersensitivity state of nerve endings. Simply soothing blood vessels (Centella asiatica) or simply antioxidating (resveratrol) is not enough to quickly reduce transient redness. The compound brown algae extract in this invention can downregulate pro-inflammatory factors, and resveratrol has a pre-blocking effect on the signaling pathway (NF-κB), enhancing the sensitivity of Centella asiatica to capillary contraction. Experiments have shown that this synergistic effect can significantly reduce the response threshold of sensory nerve endings to external stimuli. In clinical tests, the disappearance time of the "burning sensation" induced by chemical stimulation was shortened by 40% compared with the Centella asiatica alone group, and it can effectively prevent the repeated dilation of redness.

[0020] In this invention, the extracts of Fucus vesiculosus, giant kelp, bladderwort, and Chlorella were all purchased from GreenStone; the extract of Centella asiatica was purchased from Xi'an Lvtian Biotechnology Co., Ltd.; the resveratrol liposomes were purchased from LipoAvail Pharmaceuticals; and the remaining test reagents were all purchased from commercially available products.

[0021] In the terminology of this invention, "about" or "approximately" is defined as close to as understood by one of ordinary skill in the art, and in a non-limiting embodiment, the term is defined as within 10%, preferably within 5%, more preferably within 1%, and most preferably within 0.5%. The term "substantially" and its variations are defined as most, but not necessarily all, of the specified things as understood by one of ordinary skill in the art, and in a non-limiting embodiment, substantially refers to a range within 10%, within 5%, within 1%, or within 0.5%. The term "inhibit" or "reduce," or any variations thereof, includes any measurable reduction or complete inhibition to achieve the desired result. The term "promote" or "increase," or any variations thereof, includes any measurable increase or production of a protein or molecule to achieve the desired result. When used with the term "comprising" in the claims and / or specification, the absence of a quantifier before an element may indicate "one," but it also signifies "one or more," "at least one," and "one or more than one." The compositions and methods used may “contain”, “compose mainly of”, or “compose of” any of the ingredients or steps disclosed throughout this specification.

[0022] Other objects, features, and advantages of the present invention will become apparent from the following detailed description. However, it should be understood that the detailed description and embodiments are given by way of example only when illustrating specific embodiments of the invention. Furthermore, it is expected that variations and modifications within the spirit and scope of the invention will become apparent to those skilled in the art from this detailed description. Detailed Implementation

[0023] To better illustrate the purpose, technical solution, and advantages of the present invention, the present invention will be further described below in conjunction with specific embodiments.

[0024] Example 1: Screening of selective regulation of skin microecology by brown algae polysaccharides Experimental materials and grouping: Basic raw materials: Centella asiatica extract (3.0 parts), ceramide (1.0 part), resveratrol liposomes (0.5 parts); Screening raw material: brown algae extract. See Table 1 for the formula list.

[0025] Table 1 Recipe List

[0026] Effect test Test 1. Biological Barrier Test Staphylococcus epidermidis (GDMCC NO. 63065) and Staphylococcus aureus (GDMCC NO. 1.1263) were inoculated into TSB medium and cultured in a constant temperature incubator at 37°C with shaking (150 rpm) for 24 hours. The bacterial solution was then diluted with sterile physiological saline to adjust the OD value to approximately 0.1 and set aside for later use.

[0027] Dilute each composition sample with sterile water to a mass concentration of 5%, filter through a 0.22 μm filter membrane, and set aside for later use (if the viscosity of brown algae polysaccharide is high, it can be centrifuged at 500 rpm before filtration through the filter membrane).

[0028] Cultures were performed using 96-well microplates, with three replicates per group. 180 μL of TSB medium was added to each well, followed by 10 μL of the test sample, and finally 10 μL of standard bacterial suspension. An equal volume of sterile saline was used as a blank control. The plates were placed in a 37°C incubator and incubated for 48 hours.

[0029] After the culture was completed, the absorbance of each well was measured at a wavelength of 600 nm using a fully automated microplate reader (Tecan), and the colony growth rate was calculated.

[0030] Growth rate = (OD) 样品 -OD 空白 ) / OD 空白 ×100%, of which OD 样品 This indicates the absorbance value (OD) after adding the sample to be tested (and inoculating with bacterial strains). 空白 This represents the absorbance value of the control group (without added sample) after inoculation with the bacterial strain.

[0031] Antibacterial rate = (OD) 对照组 -OD 样品 ) / OD 对照组 ×100%, of which OD 对照组 This represents a normally growing bacterial group (containing only bacterial suspension and basal culture medium), OD 样品 This indicates the inflammatory bacteria group after the addition of the test sample. The results are shown in Table 2.

[0032] Table 2. The regulatory effects of the samples on the skin microbiome Composition Number Staphylococcus epidermidis growth rate Staphylococcus aureus inhibition rate 1 48.8% 57.6% 2 42.5% 42.4% 3 28.6% 48.5% 4 13.5% 18.2% 5 10.8% 5.9% 6 58.7% 69.8% 7 48.9% 62.1% 8 85.6% 87.4% 9 0.0 0.0 The results showed that, compared with single-component algal polysaccharide compositions, at similar or lower polysaccharide concentrations, composition 1 exhibited significantly higher growth-promoting rates against Staphylococcus epidermidis and inhibition rates against Staphylococcus aureus than the giant kelp and bladderwort groups. This may be because the high content of fucoidan, unique to Fucus vesiculosus polysaccharide, has more efficient antibacterial adhesion. Furthermore, when the mass fraction of Fucus vesiculosus polysaccharide was below 15%, its microecological regulatory activity decreased significantly, indicating that ensuring the polysaccharide content in Fucus vesiculosus extract plays a decisive role in exerting its antibacterial efficacy and promoting the growth of beneficial bacteria on the epidermis.

[0033] Furthermore, this experiment found that when the extracts of Fucus vesiculosus and Laminaria japonica were combined, the uronic acid in both could produce a steric hindrance effect. This combination inhibited Staphylococcus aureus by more than 80%, effectively preventing Staphylococcus aureus from colonizing the skin surface, and promoted the growth rate of Staphylococcus epidermidis by 85.6%.

[0034] Test 2. Inflammatory Factor Test HaCaT cells (purchased from Suyan Biotechnology) were seeded in 96-well plates at a density of 1×10⁶ cells / well. 5 Cells were added per well. After the cells adhered, the sample composition from Test 1 was added and pretreated for 2 hours. Then, LPS (Sigma) was added for induction for 24 hours. The groups are shown in Table 3.

[0035] Table 3 Inflammation Induction Grouping Group LPS Sample to be tested Blank group + - Model group - - test group + + After cell induction, cell supernatant was collected, and the levels of IL-6, TNF-α, IL-1β, and p-p65 were measured using ELISA (kit purchased from Suyan Biotechnology). The inhibition rate of the inflammatory factors by the test sample was calculated based on the concentration of inflammatory factors, using the following formula: Inhibition rate (%) = [(mean concentration of inflammatory factors in the LPS model group - mean concentration of inflammatory factors in the test group) / (mean concentration of inflammatory factors in the LPS model group - mean concentration of inflammatory factors in the blank group)] × 100%. The results are shown in Table 4.

[0036] Table 4. Effect of the composition on the levels of inflammatory factors in cell supernatant (inhibition rate, %) Group IL-6 IL-1β TNF-α Average inhibition rate 4 35.2 28.9 36.7 33.6 5 47.0 41.6 48.1 45.6 3 66.5 62.8 66.8 65.4 2 68.5 65.9 69.5 68.0 1 71.0 70.4 73.1 71.5 6 77.1 78.4 78.4 78.0 7 75.5 74.2 70.6 73.4 8 82.6 87.1 84.3 84.7 As shown in the table above, composition 8 exhibited the highest inhibition rate (average >84%) across all indicators. Compared to using Fucus vesiculosus alone, the combined composition increased the inhibition rate of IL-1β from 70.4% to 87.1%, demonstrating a strong synergistic effect. Furthermore, polysaccharide content is a core indicator of signaling pathway blockade, and low polysaccharide content cannot effectively control the inflammatory cascade response.

[0037] Example 2: Formulation of the composition The basic substrate ratio is shown in Table 5.

[0038] Table 5. Basic matrix formulation Classification Ingredient name Dosage (%) Liquid crystal emulsifier Cetearyl glucoside 1.0 Flow modifier Sodium polyacrylate / xanthan gum 0.5 Moisturizing oils squalane 2.0 Moisturizer glycerin 5 Macromolecular water-locking agent Sodium hyaluronate 0.5 Anti-corrosion enhancer 1,2-Hexanediol 0.8 solvent Deionized water margin The above-mentioned basic matrix was compounded with the active ingredient composition of the present invention, as shown in Table 6.

[0039] Table 6. Compound Formulation Table Components Group I Group II Group III Group IV Group V Group VI Group VII Brown algae extract (polysaccharides ≥30%) 5 10 1 0 5 5 5 Centella asiatica extract (triterpenes ≥ 80%) 2.5 5 0.5 2.5 0 2.5 2.5 Ceramide NP (liquid crystal dispersion) 1 2 0.1 1 1 0 1 Resveratrol liposomes 0.5 1 0.05 0.5 0.5 0.5 0 Basic substrate Add to 100 Add to 100 Add to 100 Add to 100 Add to 100 Add to 100 Add to 100 The brown algae extract is a compound component of composition 8 in Example 1.

[0040] The preparation method is as follows: S1. Oil phase preparation: Ceramide NP and lecithin are heated to 80°C and stirred until dissolved and homogeneous; S2. Aqueous phase preparation: Dissolve brown algae extract, centella asiatica extract and an equal volume of glycerol in deionized water, and heat to 80℃; S3. Emulsification: Add the oil phase to the aqueous phase, add the above-mentioned basic matrix, and perform homogenization emulsification to form a matrix system; S4. Addition of active substances: After the system cools down to 40-45℃, add the pre-treated resveratrol solution, stir well, and adjust the pH value to 6.0.

[0041] Effect test Test 1. Water retention effect test Eighty volunteers with sensitive and dry skin were recruited and randomly divided into eight groups. Under constant temperature and humidity (25℃, 50% relative humidity), equal amounts of the sample (3g, groups I-VII) or the base matrix (3g) were applied to the inner forearm of each participant, once in the morning and once in the evening. The skin stratum corneum moisture content was measured before application and at 2h, 6h, 12h, and 24h after application using a moisture meter. The same method and time were used for 14 consecutive days, and the moisture content was measured on the third day after discontinuation (Tewameter® Hex (Courage+Khazaka), Corneometer® CM825 (Courage+Khazaka)). Moisture retention rate = (T... 14+3d -T0) / (T 14 -T0)×100%, the results are shown in Table 7.

[0042] Table 7. Results of Moisture Content Measurement Group T0 2h 12h 24h T14 T14+3d Moisture retention rate Group I 32.4 55.6 50.2 45.8 58.6 44.5 46.20% Group II 33.8 61.2 56.4 52.1 63.5 50.4 58.70% Group III 33.1 42.5 38.2 36.4 45.2 36.8 30.60% Group IV 32.5 54.2 46.5 38.2 50.4 33.2 3.90% Group V 32 48.6 40.2 35.5 45.8 34.6 18.80% Group VI 31.6 38.4 34.2 32.8 42.5 33.5 17.40% Group VII 32.2 50.1 42.8 36.6 48.2 35.1 18.10% Basic substrate 32.7 35.8 33.2 32.5 34.6 32.4 -5.30% Therefore, it can be seen that, through observation of groups I and II, the skin moisture content was 45.8% and 52.1% respectively after 24 hours of application, significantly higher than the initial value (p < 0.05). Group VI, lacking ceramides, essentially returned to its initial state after 24 hours, demonstrating the important role of liquid crystal dispersed ceramides in constructing a physical moisture-locking barrier. Although group IV performed reasonably well at T14, its moisture content almost returned to the initial level after 3 days of discontinuation (retention rate of only 3.9%). In contrast, groups I and II, containing brown algae extract, maintained significantly higher moisture content than the control group even after discontinuation, indicating that the brown algae polysaccharide of this invention, through microecological metabolic induction, stimulates the synthesis of endogenous moisturizing factors in the skin, thereby improving skin moisture retention.

[0043] Test 2. Centella asiatica extract combined with resveratrol liposomes, see Table 8.

[0044] Table 8. Experimental Formula Table Group Centella Asiatica extract (A) Resveratrol liposomes (B) Ratio (A:B) Brown algae extract Ceramide NP (Liquid Crystal Dispersion) Group VIII 2.5 0.5 5：01 5 1 Group IX 5 0.5 10：01 5 1 Group X 2.5 0 - 5 1 Group XI 0 0.5 - 5 1 Group XII 2.5 0.05 50：01 5 1 control group 0 0 - 0 0 The compound components in Table 8 were mixed with the base components as in Test Example 1. From the aforementioned recruited volunteers, 60 subjects with sensitive skin characteristics were further screened and randomly divided into 6 groups of 10 each. A 10% lactic acid solution was applied to both sides of their noses. The high concentration of acidic stimulation rapidly penetrated the stratum corneum, activating TRPV1 in the skin's peripheral nerves, producing obvious burning, stinging, and visible instantaneous flushing. Immediately after application, a half-face control method was used, applying the samples from each group in Table 8. The time it took for the subject's subjective stinging sensation to reach zero was recorded in seconds (s). Laser speckle contrast imaging (LSCI) was used to capture changes in facial blood perfusion in real time, quantifying the flushing reduction efficiency. Furthermore, the tolerance of nerve endings to electrical stimulation was measured at a frequency of 5 Hz (unmyelinated C fibers) using a Neurotron CPT tester, assessing the improvement rate (Δ%) of nerve sensitivity. The results are shown in Table 9.

[0045] Table 9. Comparison of Neurovascular Sedative Effects Group Time for the burning sensation to subside (s) Flushing rate (15 min) Increase in neural threshold (Δ%) Frequency of recurring redness* Group VIII 142 88% 42.50% Significantly reduced Group IX 158 85% 38.20% Significantly reduced Group X 238 62% 12.50% Occasionally recurring Group XI 285 45% 21.80% obvious recurrence Group XII 225 65% 15.60% No significant improvement control group 480 12% 2.10% No improvement The results showed that the burning sensation in Group VIII disappeared in only 142 seconds, nearly 70% shorter than the 480 seconds in the blank control group. Compared with Centella asiatica alone, Group VIII's analgesic sedation speed was increased by approximately 40.3%, presumably through multi-site synergistic blocking of the TRPV1 receptor, achieving rapid pain relief. Furthermore, in terms of flushing reduction rate, Group VIII achieved an 88% reduction rate within 15 minutes. LSCI laser speckle imaging showed that the blood flow signal values ​​of the experimental group subjects rapidly returned to steady state after administration. In contrast, the redness reduction rate of resveratrol alone was only 45%, indicating that the combination of Group VIII can more effectively promote spontaneous capillary contraction by downregulating inflammatory factors.

[0046] Most importantly, Group VIII showed a 42.5% improvement in nerve threshold, indicating that the subjects' skin nerve endings were less sensitive to external stimuli and less prone to stress responses to minor environmental changes. For sensitive skin, due to the restoration of both neural and vascular homeostasis, the frequency of recurring redness in the subjects showed a significant decreasing trend.

[0047] The formulation of component VIII in this application has excellent instantaneous cooling and analgesia as well as deep neurological homeostasis regulation capabilities when dealing with acute inflammation caused by chemical irritation. It is an ideal choice for sensitive skin repair and has broad application prospects.

Claims

1. A composition, characterized in that, By weight, it includes the following active ingredients: brown algae extract: 1.0-10.0 parts, centella asiatica extract: 0.5-5.0 parts, ceramide: 0.1-2.0 parts, resveratrol liposomes: 0.05-1.0 parts.

2. The composition according to claim 1, characterized in that, The brown algae extract is at least one of the following: Fucus vesiculosus extract, giant kelp extract, or bubbly algae extract, which are rich in brown algae polysaccharide sulfate esters, and the polysaccharide mass fraction is not less than 30%.

3. The composition according to claim 1, characterized in that, The Centella asiatica extract contains asiaticoside, hydroxyasiaticoside, asiatic acid, and hydroxyasiatic acid, wherein the total triterpenoid content is greater than 80%.

4. The composition according to claim 1, characterized in that, The ceramide is selected from one or more of ceramide NP, ceramide AP, and ceramide EOP, and the ceramide is uniformly dispersed in the composition using liquid crystal emulsification technology.

5. The composition according to claim 1, characterized in that, The brown algae extract is Fucus dentata extract and / or Laminaria japonica extract.

6. The composition according to claim 1, characterized in that, The composition further includes a matrix component, which includes one or more of sodium hyaluronate, cetearyl glucoside, squalane, glycerin, xanthan gum, and 1,2-hexanediol.

7. The use of the composition according to any one of claims 1-6 in the preparation of a topical skin repair product, characterized in that, The product is used to improve redness and broken capillaries in sensitive skin, reduce inflammation, repair the physical barrier, and regulate skin microecological imbalance.

8. The application as described in claim 7, characterized in that, The product is described as an essence.

9. The method for preparing the composition according to claim 1, characterized in that, Includes the following steps: S1. Oil phase preparation: Heat ceramide and oily components to 75-85℃ and stir until dissolved and homogeneous; S2. Aqueous phase preparation: Dissolve brown algae extract, centella asiatica extract and polyol in deionized water and heat to 75-85℃; S3. Emulsification: The oil phase is added to the aqueous phase for homogeneous emulsification to form a matrix system; S4. Addition of active substances: After the system cools down to 40-45℃, add the pre-treated resveratrol solution, stir evenly, and adjust the pH value to 5.5-6.

5.

10. A serum product, characterized in that, Includes the composition according to claim 1.

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