Bionic fish digestion simulation system based on heat pump temperature control and software driving
By using an air-source heat pump for temperature control and a soft-drive mechanism, combined with a biomimetic gastrointestinal simulation system, the problems of inaccurate temperature control and mechanical simulation distortion in fish digestion simulation devices have been solved, achieving high-fidelity simulation of the digestion process and improving experimental efficiency and equipment versatility.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2026-02-03
- Publication Date
- 2026-03-31
AI Technical Summary
Existing fish digestion simulation devices have problems with inaccurate temperature control and mechanical simulation distortion, resulting in poor correlation between experimental data and real digestion results. In addition, the devices have poor versatility and are difficult to adapt flexibly to the digestive systems of different fish species.
It employs an air-source heat pump temperature control system and a soft-drive mechanism, combined with a biomimetic gastrointestinal simulation subsystem, to achieve precise temperature control and complex three-dimensional mechanical motion simulation. Through modular design and intelligent control system, it adapts to the digestive characteristics of different fish species.
It achieves high-fidelity simulation of the fish digestion process, improves the scientific rigor and reproducibility of experimental data, enhances experimental efficiency and equipment versatility, and reduces equipment investment and maintenance costs for multi-species experiments.
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Abstract
Description
Technical Field
[0001] This invention relates to the field of aquaculture and feed engineering technology, and in particular to a biomimetic fish digestion simulation system based on heat pump temperature control and software drive. Background Technology
[0002] In vitro digestion simulation technology is a key tool for evaluating the nutritional value of feed and studying digestion mechanisms. Its goal is to replicate the digestive process in vivo as realistically as possible in a laboratory environment. In the food and pharmaceutical fields, dynamic in vitro digestion models (such as TIM, DGM, and HGS systems) have made significant progress by introducing mechanical forces to simulate gastrointestinal motility, and can partially replace costly and ethically constrained in vivo experiments. However, directly applying these models and technologies, which are mainly designed for humans or mammals, to aquaculture, especially for poikilothermic fish, still presents significant adaptation problems and technological gaps.
[0003] Currently, most in vitro digestion simulation devices used for fish feed evaluation are based on simple static or semi-static methods using magnetic stirring or paddle stirring combined with a constant-temperature water bath. While these methods are easy to operate, they cannot reproduce the complex three-dimensional mechanical movements unique to the fish digestive tract, nor can they precisely control temperature, the most critical environmental factor affecting the activity of digestive enzymes in poikilothermic animals. This results in distortion of the simulation process and poor correlation between experimental data and actual in vivo digestion results.
[0004] In recent years, some researchers and institutions have attempted to improve the realism of simulations by introducing more advanced technologies, resulting in a series of related patented technologies. These technologies address the technical needs of the field from different angles, but each still has its own limitations:
[0005] In the field of biomimetic mechanical actuation, existing technologies have attempted to employ flexible actuation methods such as soft robots. For example, Chinese Patent CN105702146B, a biomimetic dynamic rat stomach-duodenal digestive system simulation device and its subsequent improvements, uses flexible mechanisms such as soft robots and magnetorheological fluids to simulate gastrointestinal peristalsis, thereby improving the realism of the simulation of the mechanical properties of biological tissues. The advancement of this type of technology lies in avoiding rigid mechanical compression and being closer to physiological states. However, their designs are usually designed for specific model animals, whose digestive tract morphology and movement patterns differ greatly from those of fish, lacking adaptability to different feeding habits, such as the U-shaped stomach of carnivorous fish and the long intestine of herbivorous fish. More importantly, the mechanical actuation modules of these systems are usually exposed to air and cannot be placed in a precisely temperature-controlled aquatic environment. For fish digestion simulation, mechanical motion simulation detached from a precise water temperature environment is incomplete.
[0006] In terms of system integration and modularization, some advanced in vitro simulation systems have considered modular design. For example, patent CN111051491B, "Gastrointestinal Simulation System, Compartments for the System, and Method therefor," describes a compartment design with standardized interfaces and an airtight cover system, facilitating assembly and sensor integration. This provides a framework for constructing complex, multi-modal digestive systems. However, existing modular designs often focus on general connections and seals, lacking rapid replacement and intelligent adaptation solutions for the diverse anatomical structures of fish digestive systems (e.g., gastric sac morphology, pyloric structure, and significant variations in intestinal length due to diet). When conducting experiments on different fish species, complex mechanical modifications or parameter resets of the equipment are often required, resulting in poor versatility and cumbersome operation.
[0007] The analysis of the closest existing patented technologies reveals that, due to distortions in mechanical simulation and inaccurate temperature control, the in vitro measurements of key indicators such as feed pellet disintegration rate and nutrient release kinetics deviate from the actual feeding and digestion of fish. Feed formulations optimized based on this data may not achieve the expected results in real-world aquaculture, wasting research and development resources. Secondly, experimental equipment is highly specialized and difficult to adjust. A single system often can only simulate limited parameters for one or two types of fish, forcing research institutions or feed companies to configure multiple sets of equipment for different research purposes or to perform time-consuming and labor-intensive manual modifications. This significantly limits experimental efficiency, increases research and development costs, and hinders the establishment of standardized evaluation systems.
[0008] To this end, we propose a biomimetic fish digestion simulation system based on heat pump temperature control and software actuation. Summary of the Invention
[0009] The present invention mainly addresses the technical problems existing in the prior art and provides a biomimetic fish digestion simulation system based on heat pump temperature control and software drive.
[0010] To achieve the above objectives, the present invention adopts the following technical solution: a biomimetic fish digestion simulation system based on heat pump temperature control and software drive, including an environmental simulation subsystem, a biomimetic stomach digestion subsystem, a biomimetic pylorus subsystem, a biomimetic intestinal subsystem, and an intelligent control and detection subsystem.
[0011] The environmental simulation subsystem includes an air-source heat pump unit, a buffer water tank, and an experimental water tank. The air-source heat pump unit is used to regulate the temperature of the water in the buffer water tank. The water in the buffer water tank is pumped into the heat exchanger in the experimental water tank via a circulating pump for secondary heat exchange to maintain a constant water temperature in the experimental water tank. The inlet pipe is led out from the bottom of the buffer water tank, and after being diverted by multiple sub-pipes, it enters the experimental water tank. The outlet pipe is located in the upper area of the experimental water tank opposite to the inlet side, and after being merged by multiple sub-pipes, it enters the main pipe and finally returns to the buffer water tank. The diversion and merging design of the multiple sub-pipes can effectively reduce water flow fluctuations and improve flow field stability. The staggered layout of the inlet and outlet can significantly increase the flow range of water in the experimental water tank, avoid the inlet water flowing directly out through the outlet pipe, and ensure the effectiveness of the experimental flow field.
[0012] The bionic gastric digestive subsystem, bionic pyloric subsystem, and bionic intestinal subsystem are set in the experimental water tank and immersed in constant temperature water. The bionic gastric digestive subsystem includes a gastric pouch made of highly elastic material and a pneumatic soft drive mechanism surrounding the gastric pouch. The pneumatic soft drive mechanism is used to periodically and asynchronously squeeze the gastric pouch to simulate the three-dimensional kneading motion of the stomach.
[0013] The biomimetic pyloric subsystem includes a digestive chamber with an inner wall fold structure, and the input end of the digestive chamber is connected to the output end of the gastric pouch.
[0014] The biomimetic intestinal subsystem includes an intestinal tube made of a highly elastic material and a peristaltic drive mechanism sleeved on the outside of the intestinal tube. The peristaltic drive mechanism is used to generate a squeezing action along the axial direction of the intestinal tube in sequence to push the contents to move unidirectionally, simulating the rhythmic peristalsis of the intestine.
[0015] The intelligent control and detection subsystem includes a PLC controller, which is used to control the actions of the pneumatic soft drive mechanism and the peristaltic drive mechanism.
[0016] Preferably, the pneumatic soft drive mechanism is a finger array composed of multiple pneumatic soft fingers, and the PLC controller controls each pneumatic soft finger in the finger array to inflate, bend and deflate in a preset timing sequence.
[0017] Preferably, the environmental simulation subsystem controls the water temperature in the experimental water tank with an accuracy of ±0.1℃.
[0018] Preferably, the peristaltic drive mechanism includes a liquid buffer layer sleeved outside the intestinal tract and a plurality of ring-shaped air bladders arranged at intervals along the axial direction, wherein the ring-shaped air bladders are disposed outside the liquid buffer layer; the PLC controller controls each of the ring-shaped air bladders to inflate and deflate in sequence, and transmits pressure to the intestinal tract through the liquid buffer layer.
[0019] Preferably, the system further includes a first injection pump for injecting gastric acid and / or pepsin into the gastric pouch, a second injection pump for injecting digestive enzymes into the digestive chamber, and a third injection pump for injecting pancreatic juice and / or bile into the intestinal tract.
[0020] Preferably, the intelligent control and detection subsystem further includes a pH sensor and / or a pressure sensor disposed in the gastric pouch and / or the intestinal tract.
[0021] Preferably, the gastric pouch, the digestive chamber, and the intestinal tract are made of medical-grade silicone; the depth of the folds in the inner wall of the digestive chamber is 2-3 mm.
[0022] Preferably, the biomimetic gastric digestive subsystem, the biomimetic pyloric subsystem, and the biomimetic intestinal subsystem are detachably connected via a flange quick-connect structure; the gastric pouch has multiple replaceable configurations to adapt to the simulation needs of different types of fish.
[0023] Beneficial effects
[0024] This invention provides a biomimetic fish digestion simulation system based on heat pump temperature control and software actuation. It has the following beneficial effects:
[0025] (1) This biomimetic fish digestion simulation system based on heat pump temperature control and software drive addresses the shortcomings of existing fish digestion simulation devices that suffer from large temperature fluctuations (often ±2-3℃) due to direct heating. This proposal innovatively integrates an air-source heat pump host, a buffer tank, and a heat exchanger in the experimental water tank. Specifically, the heat pump host first performs primary temperature regulation on the water in the buffer tank, and then pumps the regulated water into the heat exchanger in the experimental water tank via a variable frequency circulating pump for secondary heat exchange. The buffer tank plays a crucial role in effectively buffering and eliminating temperature fluctuations caused by the start-up and shutdown of the heat pump host and environmental interference. This technology allows the entire biomimetic digestive organ to be immersed in an extremely stable aquatic environment, achieving precise and stable temperature control of the experimental water tank within ±0.1℃. This fundamentally solves the problems of poor temperature uniformity and large fluctuations in traditional methods, accurately adapting to the body temperature requirements of various fish species, from cold-water to warm-water fish, providing a reliable temperature basis for simulating digestive enzyme activity, and significantly improving the scientific validity and repeatability of experimental data.
[0026] (2) This biomimetic fish digestion simulation system based on heat pump temperature control and soft drive addresses the fundamental distortion problem of traditional stirrers failing to simulate the complex three-dimensional movements of the fish digestive tract. The proposal incorporates innovative soft biomimetic drive mechanisms for both the stomach and intestines. In the stomach simulation, an array of multiple pneumatic soft fingers surrounds a silicone gastric pouch, driven by a PLC controller to periodically inflate and bend in a "non-synchronous staggered" pattern (e.g., fingers 1 and 3 contract → fingers 2 and 4 contract → all fingers release). In the intestine simulation, a ring-shaped peristaltic mechanism composed of multiple independently controllable ring-shaped air bladders is designed, with the air bladders sequentially inflating and deflating along the axial direction of the silicone intestinal tract. These techniques highly replicate the unique "three-dimensional kneading" mechanical movements of fish stomach digestion and the physiological characteristics of "rhythmic unidirectional peristalsis" in the intestines. It effectively avoids the distortion of static or simple dynamic simulations and achieves high-fidelity mechanical simulation of digestive tract motility, thus more realistically reflecting the physical disintegration and mixing process of feed particles in fish, providing core support for evaluating feed physical properties and digestive kinetics.
[0027] (3) This biomimetic fish digestion simulation system based on heat pump temperature control and soft drive addresses the challenge of adapting existing equipment to the anatomical differences of various fish species. The proposal implements two innovations in system architecture. First, modular structure: core functional units such as the biomimetic stomach pouch, pyloric digestive chamber, and intestinal tract are designed as independent modules that can be quickly disassembled and replaced via flange quick-connection. For example, a U-shaped stomach (suitable for carnivorous fish) or an I-shaped stomach (suitable for herbivorous fish) can be replaced. Second, intelligent control: micro-pressure sensors are integrated into key parts such as the stomach pouch to form a real-time closed-loop feedback, enabling the system to automatically sense and adjust parameters such as the squeezing force of the soft fingers and the peristaltic frequency of the air sac. This technology allows a single system to flexibly and quickly switch between different experimental scenarios (different fish species, different feed hardness) without requiring overall equipment modification. Evaluation shows that this design can improve the equipment's versatility by more than 80%, while significantly reducing manual intervention and parameter exploration time during experimental preparation, significantly improving experimental efficiency, and reducing the equipment investment and maintenance costs required for multi-species research. Attached Figure Description
[0028] To more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings in the following description are merely exemplary, and those skilled in the art can derive other embodiments based on the provided drawings without creative effort.
[0029] The structures, proportions, sizes, etc. illustrated in this specification are only for the purpose of assisting those skilled in the art in understanding and reading the content disclosed herein, and are not intended to limit the conditions under which the present invention can be implemented. Therefore, they have no substantial technical significance. Any modifications to the structure, changes in the proportions, or adjustments to the size, without affecting the effects and objectives that the present invention can produce, should still fall within the scope of the technical content disclosed in the present invention.
[0030] Figure 1 This is a schematic diagram of the overall structure of the present invention;
[0031] Figure 2 This is a schematic diagram of the stomach structure of the present invention;
[0032] Figure 3 This is a schematic diagram of the pyloric structure of the present invention;
[0033] Figure 4 This is a schematic diagram of the inside of the intestine according to the present invention;
[0034] Figure 5 This is a diagram of the overall simulated digestive system of the present invention;
[0035] Figure 6 This is a schematic diagram of the structure of the injection pump of the present invention.
[0036] Legend:
[0037] 1. Air source heat pump main unit; 2. Buffer water tank; 3. Experimental water tank; 4. Esophagus; 5. Stomach; 6. Pneumatic soft finger array; 7. Digestive chamber; 8. Intestine tube; 9. Liquid buffer layer; 10. Ring-shaped airbag; 11. Product collection cup; 12. PLC controller; 13. pH sensor; 14. Micro pressure sensor; 15. First injection pump; 16. Second injection pump; 17. Third injection pump. Detailed Implementation
[0038] The technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0039] Example: A biomimetic fish digestion simulation system based on heat pump temperature control and software actuation, such as... Figures 1-6As shown, the system includes an air source heat pump unit 1, which is an existing structure that outputs both heat and cold sources. A buffer water tank 2 is fixedly installed at the output end of the air source heat pump unit 1, containing water. The air source heat pump unit 1 regulates the temperature of the water in the buffer water tank 2. An experimental water tank 3 is fixedly installed at the output end of the buffer water tank 2 via a pipe. The experimental water tank 3 is a rectangular tank with an open top, and a simulated digestion module is installed inside. The system also includes a PLC controller 12 and an injection pump module.
[0040] The inlet pipe extends from the lower part of the buffer tank 2, and after being diverted by multiple sub-pipes, it connects to the experimental water tank 3. The outlet pipe is located in the upper part of the experimental water tank 3 opposite to the inlet side. After being converged by multiple sub-pipes, it connects to the main pipe and finally flows back to the buffer tank 2. The diversion and convergence design of the multiple sub-pipes can effectively reduce water flow fluctuations and improve flow field stability. The staggered layout of the inlet and outlet can significantly increase the flow range of water in the experimental water tank, prevent the inlet water from flowing directly out through the outlet pipe, and ensure the effectiveness of the experimental flow field.
[0041] The simulated digestion module includes a simulated stomach module, a simulated pylorus module, and a simulated intestine module. The simulated stomach module includes an esophagus 4, which is an L-shaped tube with a gastric pouch 5 fixedly installed at its output end. The gastric pouch 5 is made of medical-grade high-elasticity silicone material and can be reshaped according to the feeding habits of the target fish species. For example, a U-shape is suitable for carnivorous fish, and an I-shape is suitable for herbivorous fish, used to hold feed and digestive juices. The gastric pouch 5 is externally wrapped with a pneumatic soft finger array 6, which consists of at least four pairs of biomimetic pneumatic fingers, each pair of pneumatic fingers symmetrically arranged on both sides of the gastric pouch 5. When the pneumatic soft finger array 6 is working, it operates in a preset sequence: first, the first and third pairs of fingers contract and squeeze, then the second and fourth pairs of fingers contract and squeeze, and finally all fingers release simultaneously, thus achieving asynchronous staggered squeezing in a cycle to simulate the three-dimensional kneading motion of the stomach wall. The gastric pouch 5 also contains a pH sensor 13 and a miniature pressure sensor 14 for real-time monitoring of pH and pressure changes during digestion.
[0042] The simulated pylorus module includes a digestive chamber 7, which consists of a tube connected to the pyloric lumen. The pyloric lumen is made of highly elastic silicone material, and its inner wall has a 2-3 mm deep pleated structure to increase the specific surface area and enhance the adhesion of digestive enzymes, thereby replicating the digestive function of the pylorus. The input end of the digestive chamber 7 is fixedly connected to the output end of the gastric pouch 5.
[0043] The simulated intestinal module includes an intestinal tube 8, made of medical-grade high-elasticity silicone material, arranged along a horizontal axis to support the mixing and reaction of chyme and digestive juices. A liquid buffer layer 9 is fitted around the outside of the intestinal tube 8, with a buffer solution (e.g., water) filling the space between the liquid buffer layer 9 and the intestinal tube 8. Multiple sets of ring-shaped air bladders 10 are evenly distributed along the axial direction on the outer wall of the liquid buffer layer 9. By sequentially inflating and deflating the ring-shaped air bladders 10 along the intestinal tube 8 from front to back, the intestinal tube 8 can be gradually compressed, pushing the chyme inside to move unidirectionally towards the end, simulating the rhythmic peristalsis of the intestine. A pH sensor 13 is also installed inside the intestinal tube 8 to monitor changes in the intestinal pH. A PLC controller 12 is connected to each ring-shaped air bladder 10 to control their sequential activation.
[0044] The injection pump module includes a first injection pump 15, a second injection pump 16, and a third injection pump 17. The first injection pump 15 is a gastric acid / pepsin injection pump, with its output connected to the gastric sac 5, used to control the injection time and rate of gastric acid and pepsin to match the physiological rhythm of gastric digestion in fish. The second injection pump 16 is a digestive enzyme injection pump, with its output connected to the digestive chamber 7, used to inject proteases, amylases, and lipases to regulate the enzymatic reaction process. The third injection pump 17 is a pancreatic juice / bile injection pump, with its output connected to the intestinal tract 8, used to control the injection parameters of pancreatic juice and bile to meet the enzymatic reaction requirements during intestinal digestion.
[0045] The system also includes a product collection cup 11 at the end for collecting the products after simulated digestion, which can then be used for subsequent component analysis. The modules are detachably connected via flange quick-connect fittings, allowing for easy replacement or adjustment of components as needed, thus adapting to digestion simulation experiments with different fish species or feeds.
[0046] A biomimetic fish digestion simulation method based on heat pump temperature control and software actuation is also provided, including the following steps:
[0047] The environmental simulation subsystem is used to adjust and stabilize the water in the experimental tank (3) at the target temperature.
[0048] The feed is placed into the stomach pouch (5), and the stomach pouch (5) is periodically and asynchronously squeezed by the pneumatic soft drive mechanism, while the digestive juice is injected to simulate stomach digestion.
[0049] The chyme that has been partially digested in the stomach enters the digestive chamber (7) for further enzymatic digestion;
[0050] The chyme enters the intestinal tract (8) and is driven to move unidirectionally along the intestinal axis by the peristaltic drive mechanism, while the injection of intestinal fluid is controlled to simulate intestinal digestion;
[0051] The intelligent control and detection subsystem monitors parameters during the digestion process and controls the coordinated operation of each mechanism.
[0052] The target temperature is set according to the physiological body temperature of the target fish species, with a control accuracy of ±0.1℃; the action sequence of the pneumatic soft drive mechanism and the start-up sequence and frequency of the peristaltic drive mechanism are set and adjusted according to the digestive physiological characteristics of the target fish species.
[0053] The working principle of this invention is as follows: First, the air source heat pump unit 1 performs preliminary temperature regulation on the water in the buffer tank 2. Then, the water at a stable temperature is transported to the heat exchanger in the experimental water tank 3 via a variable frequency circulating pump for secondary heat exchange, thereby precisely and stably controlling the temperature of the water in the tank at the set value, providing a constant temperature environment for the entire biomimetic digestion process. At the start of the simulation, the feed enters the stomach sac 5 through the esophagus 4. The first injection pump 15 injects gastric acid and pepsin according to the program. At the same time, the pneumatic soft finger array 6, under the control of the PLC controller 12, periodically squeezes and relaxes the stomach sac 5 in a set asynchronous sequence, simulating the three-dimensional kneading motion of the stomach to physically break down the feed. The pre-digested chyme then enters the digestive chamber 7 with a pleated structure, where the second injection pump 16 injects various digestive enzymes to enhance the enzymatic reaction. The chyme then enters the intestinal tract 8, where a third injection pump 17 injects pancreatic juice and bile. Simultaneously, the ring-shaped air bladder 10, driven by the PLC controller 12, sequentially inflates and deflates axially, compressing the liquid buffer layer 9 and the intestinal tract 8, generating unidirectional rhythmic peristaltic waves that propel and further digest the chyme. Throughout the process, the pH sensor 13 and the miniature pressure sensor 14 monitor the environmental parameters within the digestive cavity in real time, feeding the data back to the control system, enabling closed-loop adaptive adjustment of digestive motion parameters. Finally, the digestive products are pushed into the product collection cup 11 for collection. The entire system, through the synergistic effect of the aforementioned temperature control, mechanical motion simulation, precise enzyme injection, and intelligent feedback, faithfully reproduces the continuous digestive physiological process of fish from stomach to intestine.
[0054] The foregoing has shown and described the basic principles, main features, and advantages of the present invention. Those skilled in the art should understand that the present invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to the invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the present invention as claimed. The scope of protection of this invention is defined by the appended claims and their equivalents.
Claims
1. A bionic fish digestion simulation system based on heat pump temperature control and software driving, characterized in that, The system comprises an environment simulation subsystem, a bionic stomach digestion subsystem, a bionic pylorus subsystem, a bionic intestinal tract subsystem and an intelligent control and detection subsystem. The environment simulation subsystem comprises an air source heat pump main machine (1), a buffer water tank (2) and an experimental water tank (3). The air source heat pump main machine (1) is used for adjusting the temperature of water in the buffer water tank (2). The water in the buffer water tank (2) is pumped into a heat exchanger in the experimental water tank (3) by a circulating pump for secondary heat exchange, so as to maintain the constant temperature of water in the experimental water tank (3). The lower part of the buffer water tank (2) is provided with an inlet pipeline which is connected to the experimental water tank (3) through multiple branch pipelines. The upper part of the experimental water tank (3) opposite to the water inlet side is provided with an outlet pipeline which is connected to the buffer water tank (2) through multiple branch pipelines. The bionic stomach digestion subsystem, the bionic pylorus subsystem and the bionic intestinal tract subsystem are arranged in the experimental water tank (3) and immersed in the constant temperature water. The bionic stomach digestion subsystem comprises a stomach bag (5) made of high elasticity material and a pneumatic soft body driving mechanism surrounding the stomach bag (5). The pneumatic soft body driving mechanism is used for periodically and asynchronously extruding the stomach bag (5) to simulate the three-dimensional rubbing motion of the stomach. The bionic pylorus subsystem comprises a digestion chamber (7) with an inner wall wrinkle structure. The input end of the digestion chamber (7) is connected to the output end of the stomach bag (5). The bionic intestinal tract subsystem comprises an intestinal canal (8) made of high elasticity material and a peristalsis driving mechanism surrounding the intestinal canal (8). The peristalsis driving mechanism is used for sequentially generating extrusion along the axis of the intestinal canal (8) to push the contents to move in one direction, simulating the intestinal rhythmic peristalsis. The intelligent control and detection subsystem comprises a PLC controller (12) which is used for controlling the actions of the pneumatic soft body driving mechanism and the peristalsis driving mechanism.
2. The bionic fish digestion simulation system based on heat pump temperature control and software driving according to claim 1, characterized in that: The pneumatic soft body driving mechanism is a finger array (6) composed of multiple pneumatic soft fingers. The PLC controller (12) controls each pneumatic soft finger in the finger array (6) to inflate and bend according to a preset time sequence and to deflate and reset.
3. The bionic fish digestion simulation system based on heat pump temperature control and software driving according to claim 1, characterized in that: The control precision of the environment simulation subsystem for the water temperature in the experimental water tank (3) is ±0.1℃.
4. The bionic fish digestion simulation system based on heat pump temperature control and software driving according to claim 1, characterized in that: The peristalsis driving mechanism comprises a liquid buffer layer (9) surrounding the intestinal canal (8) and multiple ring air bags (10) arranged along the axis at intervals. The ring air bags (10) are arranged outside the liquid buffer layer (9). The PLC controller (12) controls each ring air bag (10) to inflate and deflate in sequence, and transmits the pressure to the intestinal canal (8) through the liquid buffer layer (9).
5. The bionic fish digestion simulation system based on heat pump temperature control and software driving according to claim 1, characterized in that: The system further comprises a first injection pump (15) for injecting gastric acid and / or pepsin into the stomach bag (5), a second injection pump (16) for injecting digestive enzymes into the digestion chamber (7), and a third injection pump (17) for injecting pancreatic juice and / or bile into the intestinal canal (8).
6. The bionic fish digestion simulation system based on heat pump temperature control and software driving according to claim 1, characterized in that: The intelligent control and detection subsystem further comprises a pH sensor (13) and / or a pressure sensor (14) arranged in the stomach sac (5) and / or the intestinal canal (8).
7. The bionic fish digestion simulation system based on heat pump temperature control and software driving according to claim 1, characterized in that: The stomach sac (5), the digestive chamber (7) and the intestinal canal (8) are made of medical-grade silica gel; the wrinkle depth of the inner wall of the digestive chamber (7) is 2-3 mm.
8. The bionic fish digestion simulation system based on heat pump temperature control and software driving according to any one of claims 1-7, characterized in that: The bionic stomach digestion subsystem, the bionic pylorus subsystem and the bionic intestinal canal subsystem are detachably connected through a flange quick connection structure; the stomach sac (5) has replaceable multiple configurations to adapt to the simulation requirements of different fish species.
Citation Information
Patent Citations
Bionic dynamic mouse gastroduodenal digestive system simulation device and simulation experiment method
CN105702146B
Gastrointestinal tract simulation system, compartments and methods for using it
CN111051491B