A fully automatic chemiluminescence immunoassay analyzer
By utilizing the automatic isolation and temperature control functions of the reagent processing unit in the fully automated chemiluminescence immunoassay analyzer, combined with the linkage design of the isolation and drive components, the problems of equipment susceptibility to contamination and high energy consumption are solved. Stable storage and precise positioning of samples and reagents are achieved, ensuring continuous operation of the equipment in the event of a failure, and improving the integration and reliability of the equipment.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Patents(China)
- Current Assignee / Owner
- RELIA BIOTECH JIANGSU
- Filing Date
- 2026-03-04
- Publication Date
- 2026-06-26
AI Technical Summary
Existing fully automated chemiluminescence immunoassay analyzers are susceptible to air pollution and humidity, have high energy consumption, and their multi-motor control mode makes them prone to failure and requires manual intervention for recovery.
By employing the automatic isolation and temperature control functions of the reagent processing unit, combined with the linkage design of the isolation component and the drive component, stable storage and precise positioning of samples and reagents are achieved, reducing the intrusion of external contaminants and optimizing energy consumption, while maintaining continuous operation of the equipment in the event of a failure.
It effectively prevents external pollutants and moisture from intruding, reduces energy consumption, improves equipment integration and reliability, ensures the stability of samples and reagents, ensures continuous operation of equipment, improves equipment integration and working efficiency, ensures the stability of samples and reagents, achieves equipment continuity and reliability, achieves continuous operation of equipment stability and reliability, improves equipment reliability, improves equipment integration and reliability, and improves equipment reliability.
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Figure CN121784311B_ABST
Abstract
Description
Technical Field
[0001] This invention relates to the field of immunoassay analyzer technology, specifically a fully automated chemiluminescence immunoassay analyzer. Background Technology
[0002] Chemiluminescence immunoassay, as one of the core technologies in the field of modern medical testing, achieves highly sensitive detection of biomarkers through chemiluminescence signals. It plays an irreplaceable role in scenarios such as infectious disease screening, tumor marker analysis, and hormone level monitoring. Currently, fully automated chemiluminescence immunoassay analyzers are usually based on the direct chemiluminescence method of acridinium esters, using paramagnetic microparticles as carriers and combining antigen-antibody immune reactions to analyze the content of analytes in the human body.
[0003] For example, patents “CN110873803A Fully Automated Chemiluminescence Analyzer” and “CN115541907A Fully Automated Chemiluminescence Immunoassay Analyzer” disclose a chemiluminescence immunoassay technology. However, existing chemiluminescence immunoassay analyzers generally use open or semi-open reagent storage units. When not in operation, reagents and samples are easily contaminated by moisture, dust and microorganisms in the air. In addition, existing equipment usually adopts an overall temperature control mode, which can easily lead to energy waste. Finally, most current chemiluminescence immunoassay analyzers adopt a multi-motor independent control mode, with each component driven by a separate motor. Once a motor fails, the entire detection process will be forced to stop, and manual intervention is often required to continue working. Summary of the Invention
[0004] The purpose of this invention is to provide a fully automated chemiluminescence immunoassay analyzer to solve the problems raised in the prior art.
[0005] To achieve the above objectives, the present invention provides the following technical solution: a fully automated chemiluminescence immunoassay analyzer, comprising a main housing and a front housing, the front housing being disposed on the side of the main housing, a reaction disk being disposed inside the main housing, and a transport assembly, a sampling assembly, a gripper assembly, a photometric assembly, a mixing assembly, and a magnetic separation assembly being disposed around the reaction disk, an opening being provided on the front housing, a cover plate being disposed above the opening, a reagent processing unit being disposed inside the front housing, and a display screen being disposed on the outer side of the front housing, wherein, during operation, the operator can place the reaction cup into the transport assembly, and through the cooperation of the transport assembly and the gripper assembly, the reaction cup is placed onto the reaction disk. The sample and reagents in the reagent processing unit are collected into the reaction cup by the sampling component. The sample and reagents are mixed and purified by the mixing component and the magnetic separation component. The final luminescence value of the sample and reagents in the reaction cup is detected by the photometric component, and the result is output to the software system on the display screen. Compared with the current fully automated chemiluminescence immunoassay analyzer, the reagent processing unit in this invention has automatic isolation and temperature control functions. On the one hand, it ensures that the reagent processing unit can be effectively isolated from the external environment and the environment inside the main shell when the analyzer is not working, avoiding the intrusion of external pollutants and moisture, and ensuring the stability of the sample and reagents. On the other hand, it reduces the temperature control area of the reagent processing unit and reduces energy consumption.
[0006] Furthermore, a hopper is provided above the main housing, and the hopper is aligned with the inlet end of the conveying component. The conveying component has an automatic sorting function. With the cooperation of the hopper and the conveying component, the operator does not need to place the reaction cups into the conveying component individually. During operation, a large number of reaction cups can be put into the hopper at once, and the unordered reaction cups can be sorted and conveyed by the conveying component, thereby reducing the labor intensity of the operator.
[0007] Furthermore, the reagent processing unit includes a sample box, an isolation component on top of the sample box, a placement cavity at the upper interior of the sample box, a control cavity at the lower interior of the sample box, a storage component inside the placement cavity, and a drive component and a cooling component inside the control cavity. The storage component carries the sample and reagent, and the drive component controls the position of the sample and reagent to facilitate the sampling component in taking specific samples and reagents. In the non-working state, the present invention controls the temperature inside the placement cavity through the cooling component to ensure the stability of the sample and reagent performance inside the storage component. The isolation component separates the placement cavity from the external environment and the environment inside the main shell, preventing the intrusion of external pollutants and moisture, while reducing the energy consumption of the cooling component.
[0008] Furthermore, the isolation assembly includes a fixed cover, a mounting bracket, and a movable cover. The inner walls of both the fixed cover and the movable cover are coated with a heat insulation layer. The mounting bracket is fixedly installed above the side end of the front housing, and an isolation motor is installed inside the mounting bracket. The fixed cover is fixedly installed above the sample box, and the movable cover is movably installed inside the fixed cover. The isolation motor and the movable cover are connected by a linkage assembly. When the invention is in operation, the movable cover is driven by the isolation motor to move directly below the fixed cover. When the invention is not in operation, the movable cover is driven by the isolation motor to move to a position perpendicular to the fixed cover. At this time, the fixed cover and the movable cover isolate the placement cavity from the external environment and the environment inside the main housing, thereby preventing the intrusion of external pollutants and moisture, and reducing the energy consumed by the cooling assembly to keep the placement cavity at a low temperature.
[0009] Furthermore, the fixed cover has a first through hole, the movable cover has a second through hole, and the mounting bracket also houses a fan. The fan's air inlet is connected to the first through hole via a duct, and the fan blades inside the fan are connected to the main shaft of the isolation motor. One end of the cooling component is connected to the external environment via a filter, and the other end of the cooling component is connected to the placement chamber (not shown in the figure) via a solenoid valve. This invention controls the connection state between the isolation motor and the movable cover through a linkage component. When the operator needs to change the position of the movable cover, the linkage component is in the open state. At this time, the isolation motor drives the movable cover to rotate, so that... The movable cover is located directly below or perpendicular to the fixed cover (when the movable cover is directly below the fixed cover, the first and second through holes are offset; when the movable cover is perpendicular to the fixed cover, the first and second through holes are aligned). When the invention is not in operation (i.e., the movable cover is perpendicular to the fixed cover), the operator can turn off the linkage component. At this time, the isolation motor will not be able to drive the movable cover to move. Then the operator can turn on the isolation motor, which drives the fan blades inside the fan to rotate, thereby drawing away the gas in the placement chamber. This facilitates the subsequent opening of the solenoid valve, allowing purified and cooled air to enter the placement chamber to ensure the refrigeration effect of the samples and reagents.
[0010] Furthermore, the linkage component includes a first electromagnet and a permanent magnet. The permanent magnet is embedded at the lower center of the movable cover. The first electromagnet is located below the permanent magnet and connected to the main shaft of the isolation motor. This invention controls the connection state between the isolation motor and the movable cover by opening and closing the first electromagnet. When the first electromagnet is opened and generates a magnetic field that attracts the permanent magnet, the first electromagnet and the permanent magnet will be fastened together. At this time, the movable cover can be moved by the isolation motor. When the first electromagnet is closed, the first electromagnet and the permanent magnet will separate. At this time, the movable cover cannot be moved by the isolation motor, so as to facilitate the subsequent driving of the fan blades inside the fan by the isolation motor. Through the above technical solution, this invention realizes the coordinated control of multiple functions on the basis of a single drive source, which significantly improves the integration and reliability of the equipment.
[0011] Furthermore, the driving assembly includes a shifting motor and a transmission frame. One end of the transmission frame is connected to the storage assembly, and the other end of the transmission frame is connected to the bottom of the sample box via an angle detection element. The shifting motor and the transmission frame are connected via a gear assembly. This invention drives the transmission frame and the storage assembly to rotate via the shifting motor, so as to change the position of specific samples and reagents as needed. The angle detection element detects whether the rotation angle of the transmission frame and the storage assembly is correct, avoiding deviations in the rotation angle that could prevent the sampling assembly from accurately picking up specific samples and reagents.
[0012] Furthermore, the sample box is also equipped with a collaborative component, and the isolation component and the driving component are connected through the collaborative component.
[0013] Furthermore, the collaborative component includes a collaborative frame and a second electromagnet. The collaborative frame is disposed on the inner side of the placement cavity, and the second electromagnet is disposed on the upper inner side of the control cavity. The collaborative frame is connected to the movable cover, and the end of the collaborative frame near the second electromagnet is made of ferromagnetic material. The second electromagnet is connected to the transmission frame via a bracket. When the shifting motor is working normally, the collaborative component is in a non-working state (the second electromagnet is not turned on). When the shifting motor malfunctions, making it impossible to move the transmission frame and the storage component to the accurate position, the operator can turn on the second electromagnet. The second electromagnet magnetically attracts the collaborative frame, allowing the collaborative frame and the second electromagnet to rotate synchronously. After the second electromagnet and the collaborative frame are fixed together, the movable cover, the collaborative frame, the second electromagnet, and the transmission frame are driven to rotate synchronously by an isolation motor. When the transmission frame rotates to a specific position, the second electromagnet is turned off, and the movable cover is driven back to the position directly below the fixed cover by the isolation motor to prevent interference with the subsequent sampling component's collection of specific samples and reagents. Through the above technical solution, the present invention can ensure the continuity of work and improve work efficiency.
[0014] Furthermore, the storage component includes a sample tray with several sets of support racks. Each set of support racks contains several reagent bottles. A sample rack is provided between each pair of adjacent support racks. Each sample rack has three sample positions to support sample tubes of different sizes.
[0015] Compared with the prior art, the beneficial effects of the present invention are:
[0016] 1. Compared with current analyzers, this invention has a reagent processing unit and its supporting isolation components. The isolation components create a high-precision sample and reagent storage environment, fundamentally solving the problems of traditional analyzers being susceptible to external contamination and excessive energy consumption when not in operation. When not in operation, this invention forms a double heat insulation barrier through the vertical closure of the movable cover and the fixed cover, which can effectively block external heat exchange. Combined with the linkage temperature control mechanism of the fan and the cooling components, the temperature of the placement chamber is stably controlled within a suitable range. Through the above technical solutions, this invention not only avoids the corrosion of sample reagents by external pollutants and moisture, but also greatly reduces the energy consumption of the cooling components by precisely limiting the temperature control area.
[0017] 2. This invention ensures that the reagent processing unit has fault redundancy capability through the linkage of the drive component, isolation component and coordination component. The displacement motor in the drive component, combined with the angle detection element, can accurately control the positioning accuracy of the sample reagent, ensuring that the sampling component can quickly and accurately acquire the target sample. When the displacement motor fails, the coordination component transmits the driving force of the isolation motor to the transmission frame through the magnetic attraction coordination frame of the second electromagnet, realizing the synchronous rotation of the movable cover and the storage component. This allows the equipment to complete the current detection process even when there is a partial failure, effectively improving work efficiency. In addition, the single drive source (isolation motor) in this invention achieves multi-functional coordinated control through the linkage component, which significantly improves the integration and reliability of the equipment.
[0018] 3. This invention achieves full automation of reaction cup processing through the collaborative design of the hopper and intelligent conveying components. Workers can batch-feed disordered reaction cups at once, and adjust the cup posture through the conveying components to ensure that each reaction cup enters the grasping area in a uniform posture. Finally, this invention sets three sample positions of different sizes on each sample rack to support sample tubes of different specifications. Attached Figure Description
[0019] Figure 1 This is a schematic diagram of the overall structure of the present invention;
[0020] Figure 2 This is a schematic diagram showing the location of the reagent processing unit of the present invention;
[0021] Figure 3 This is a schematic diagram of the internal structure of the main housing of the present invention;
[0022] Figure 4 This is a schematic diagram of the reagent processing unit structure of the present invention;
[0023] Figure 5 This is a schematic diagram of the isolation component structure of the present invention;
[0024] Figure 6 This is a schematic diagram of the movable cover structure of the present invention;
[0025] Figure 7 This is a first-view schematic diagram of the fixed cover of the present invention;
[0026] Figure 8 This is a second-view schematic diagram of the fixed cover of the present invention;
[0027] Figure 9 This is a schematic diagram of the drive component structure of the present invention.
[0028] In the diagram: 1. Main shell; 11. Hopper; 12. Conveying assembly; 13. Sampling assembly; 14. Reaction plate; 15. Handle assembly; 16. Photometric assembly; 17. Mixing assembly; 18. Magnetic separation assembly; 2. Display screen; 3. Front shell; 31. Cover plate; 32. Reagent processing unit; 321. Sample box; 322. Fixed cover; 3221. First through hole; 323. Mounting frame; 3231. Isolation motor; 3232. First electromagnet; 3233. Fan; 3234. Conduit; 324. Support frame; 3241. Reagent bottle; 325. Movable cover; 3251. Second through hole; 3252. Permanent magnet; 3253. Coordination frame; 326. Sample rack; 327. Sample tray; 328. Transposition motor; 329. Transmission frame; 3291. Angle detection element; 3292. Second electromagnet. Detailed Implementation
[0029] Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.
[0030] Example: Figures 1-9As shown, this invention provides a technical solution: a fully automated chemiluminescence immunoassay analyzer. The analyzer includes a main housing 1 and a front housing 3. The front housing 3 is located at the side of the main housing 1. A reaction plate 14 is disposed inside the main housing 1. A conveying assembly 12, a sampling assembly 13, a gripper assembly 15, a photometric assembly 16, a mixing assembly 17, and a magnetic separation assembly 18 are arranged around the reaction plate 14. An opening is provided on the front housing 3, and a cover plate 31 is provided above the opening. A reagent processing unit 32 is disposed inside the front housing 3, and a display screen 2 is disposed on the outside of the front housing 3. During operation, the operator can place the reaction cup into the conveying assembly 12, and the reaction cup is placed onto the reaction plate 14 through the cooperation of the conveying assembly 12 and the gripper assembly 15. The sample and reagents in the reagent processing unit 32 are taken into the reaction cup by the sampling component 13. The sample and reagents are mixed and purified by the mixing component 17 and the magnetic separation component 18. The final luminescence value of the sample and reagents in the reaction cup is detected by the photometric component 16, and the result is output to the software system in the display screen 2. Compared with the current fully automated chemiluminescence immunoassay analyzer, the reagent processing unit 32 in this invention has automatic isolation and temperature control functions. On the one hand, it ensures that when the analyzer is not working, the reagent processing unit 32 can be effectively isolated from the external environment and the environment inside the main shell 1, avoiding the intrusion of external pollutants and moisture, and ensuring the stability of the sample and reagents. On the other hand, it reduces the temperature control area of the reagent processing unit 32 and reduces energy consumption.
[0031] like Figures 1-3 As shown, a hopper 11 is provided above the main housing 1. The hopper 11 is aligned with the inlet end of the conveying assembly 12. The conveying assembly 12 has an automatic sorting function. With the cooperation of the hopper 11 and the conveying assembly 12, the operator does not need to place the reaction cups into the conveying assembly 12 separately. During operation, a large number of reaction cups can be put into the hopper 11 at one time, and the unordered reaction cups can be sorted and conveyed by the conveying assembly 12, thereby reducing the labor intensity of the operator.
[0032] like Figures 3-4 , Figure 9 As shown, the reagent processing unit 32 includes a sample box 321. An isolation component is provided above the sample box 321. A placement cavity is provided at the upper end of the sample box 321, and a control cavity is provided at the lower end of the sample box 321. A storage component is provided inside the placement cavity, and a drive component and a cooling component are provided inside the control cavity. The storage component carries the sample and reagent, and the drive component controls the position of the sample and reagent to facilitate the sampling component 13 to take specific samples and reagents. In the non-working state, the present invention controls the temperature inside the placement cavity through the cooling component to ensure the stability of the sample and reagent performance inside the storage component. The isolation component separates the placement cavity from the external environment and the environment inside the main shell 1, avoiding the intrusion of external pollutants and moisture, while reducing the energy consumption of the cooling component.
[0033] like Figures 4-8 As shown, the isolation assembly includes a fixed cover 322, a mounting bracket 323, and a movable cover 325. The inner walls of both the fixed cover 322 and the movable cover 325 are coated with a heat-insulating layer. The mounting bracket 323 is fixedly installed above the side end of the front housing 3. An isolation motor 3231 is disposed inside the mounting bracket 323. The fixed cover 322 is fixedly installed above the sample box 321, and the movable cover 325 is movably installed inside the fixed cover 322. The isolation motor 3231 and the movable cover 325 are connected via a linkage assembly. When the invention is in operation, the isolation motor 3231 drives the movable cover 325 to move directly below the fixed cover 322 (e.g., ...). Figure 4 As shown), when the present invention is in a non-working state, the movable cover 325 is driven by the isolation motor 3231 to move to a position perpendicular to the fixed cover 322. At this time, the fixed cover 322 and the movable cover 325 isolate the placement cavity from the external environment and the environment inside the main housing 1, thereby preventing the intrusion of external pollutants and moisture, and reducing the energy consumed by the refrigeration components to keep the placement cavity at a low temperature.
[0034] like Figures 4-8 As shown, the fixed cover 322 has a first through hole 3221, and the movable cover 325 has a second through hole 3251. A fan 3233 is also installed inside the mounting bracket 323. The air inlet of the fan 3233 is connected to the first through hole 3221 via a conduit 3234. The fan blades inside the fan 3233 are connected to the main shaft of the isolation motor 3231. One end of the cooling component is connected to the external environment via a filter, and the other end of the cooling component is connected to the placement chamber (not shown in the figure) via a solenoid valve. This invention controls the connection state between the isolation motor 3231 and the movable cover 325 through a linkage component. When the operator needs to change the position of the movable cover 325, the linkage component is in the open state. At this time, the isolation motor 3231 drives the movable cover 325 to rotate, so that the movable cover 325 is in the fixed position. The movable cover 325 is located directly below the fixed cover 322 or perpendicular to the fixed cover 322 (when the movable cover 325 is directly below the fixed cover 322, the first through hole 3221 and the second through hole 3251 are offset; when the movable cover 325 is perpendicular to the fixed cover 322, the first through hole 3221 and the second through hole 3251 are aligned). When the invention is in a non-working state (i.e., the movable cover 325 is perpendicular to the fixed cover 322), the operator can turn off the linkage component. At this time, the isolation motor 3231 will not be able to drive the movable cover 325 to move. Then the operator can turn on the isolation motor 3231, which drives the fan blades in the fan 3233 to rotate, thereby drawing away the gas in the placement chamber. This facilitates the subsequent opening of the solenoid valve, allowing purified and cooled air to enter the placement chamber to ensure the refrigeration effect of the samples and reagents.
[0035] like Figures 5-8 As shown, the linkage component includes a first electromagnet 3232 and a permanent magnet 3252. The permanent magnet 3252 is embedded in the lower center of the movable cover 325. The first electromagnet 3232 is located below the permanent magnet 3252 and connected to the main shaft of the isolation motor 3231. This invention controls the connection state between the isolation motor 3231 and the movable cover 325 by opening and closing the first electromagnet 3232. When the first electromagnet 3232 is turned on and generates a magnetic field that attracts the permanent magnet 3252, the first electromagnet 3232 and the permanent magnet 3252... The bodies 3252 will be fastened together. At this time, the movable cover 325 can be moved by the isolation motor 3231. When the first electromagnet 3232 is closed, the first electromagnet 3232 and the permanent magnet 3252 will be separated. At this time, the movable cover 325 can no longer be moved by the isolation motor 3231, so as to facilitate the subsequent drive of the fan blades in the fan 3233 by the isolation motor 3231. Through the above technical solution, the present invention realizes the coordinated control of multiple functions on the basis of a single drive source, which significantly improves the integration and reliability of the equipment.
[0036] like Figure 9 As shown, the driving assembly includes a transposition motor 328 and a transmission frame 329. One end of the transmission frame 329 is connected to the storage assembly, and the other end of the transmission frame 329 is connected to the bottom of the sample box 321 via an angle detection element 3291. The transposition motor 328 and the transmission frame 329 are connected via a gear assembly. In this invention, the transposition motor 328 drives the transmission frame 329 and the storage assembly to rotate, so as to change the position of specific samples and reagents as needed. The angle detection element 3291 detects whether the rotation angle of the transmission frame 329 and the storage assembly is correct, avoiding deviations in the rotation angle that would prevent the sampling assembly 13 from accurately taking specific samples and reagents.
[0037] like Figure 9 As shown, the sample box 321 is also equipped with a collaborative component, and the isolation component and the driving component are connected through the collaborative component.
[0038] like Figure 9As shown, the collaborative component includes a collaborative frame 3253 and a second electromagnet 3292. The collaborative frame 3253 is located inside the placement cavity, and the second electromagnet 3292 is located inside the control cavity. The collaborative frame 3253 is connected to the movable cover 325, and the end of the collaborative frame 3253 near the second electromagnet 3292 is made of ferromagnetic material. The second electromagnet 3292 is connected to the transmission frame 329 via a bracket. When the shifting motor 328 is working normally, the collaborative component is in a non-working state (the second electromagnet 3292 is not activated). When the shifting motor 328 malfunctions and cannot move the transmission frame 329 and the storage component to the accurate position, the operator can activate the second electromagnet 3292. The magnetically attracted cooperating frame 3253 (iron 3292) allows the cooperating frame 3253 and the second electromagnet 3292 to rotate synchronously. After the second electromagnet 3292 and the cooperating frame 3253 are fixed together, the movable cover 325, the cooperating frame 3253, the second electromagnet 3292, and the transmission frame 329 are driven to rotate synchronously by the isolation motor 3231. When the transmission frame 329 rotates to a specific position, the second electromagnet 3292 is closed, and the movable cover 325 is driven by the isolation motor 3231 to return to the position directly below the fixed cover 322 to prevent interference with the subsequent sampling component 13 in taking specific samples and reagents. Through the above technical solution, the present invention can ensure the continuity of work and improve work efficiency.
[0039] like Figure 4 and Figure 9 As shown, the storage component includes a sample tray 327, on which several sets of support racks 324 are provided. Each set of support racks 324 contains several reagent bottles 3241. A sample rack 326 is provided between two adjacent sets of support racks 324. Each sample rack 326 has three sample positions to support sample tubes of different sizes.
[0040] The working principle of this invention is as follows: During operation, the operator can place a large number of reaction cups into the hopper 11 at once. The unordered reaction cups are sorted and transported by the conveying component 12. The reaction cups are then gripped onto the reaction plate 14 by the gripper component 15. The operator can then activate the transfer motor 328 to bring the target sample and reagent closer to the sampling component 13. The sampling component 13 takes the sample and reagent from the reagent processing unit 32 into the reaction cup. The sample and reagent are mixed and purified by the mixing component 17 and the magnetic separation component 18. The final luminescence value of the sample and reagent in the reaction cup is detected by the photometric component 16, and the result is output to the software system on the display screen 2. When the operation is completed... Afterwards, the staff can turn on the isolation motor 3231 and the linkage component. The isolation motor 3231 drives the movable cover 325 to move to a position perpendicular to the fixed cover 322. The fixed cover 322 and the movable cover 325 isolate the placement chamber from the external environment and the environment inside the main housing 1. When the movable cover 325 moves to a specific position, the linkage component is turned off. At this time, the isolation motor 3231 is turned on again and the speed of the isolation motor 3231 is adjusted so that the isolation motor 3231 drives the fan blades in the fan 3233 to rotate, thereby drawing away the gas in the placement chamber. Finally, the cooling component and the solenoid valve are turned on, and the purified and cooled air will enter the placement chamber, thereby ensuring the refrigeration effect of the samples and reagents.
[0041] Finally, it should be noted that the above descriptions are merely preferred embodiments of the present invention and are not intended to limit the present invention. Although the present invention has been described in detail with reference to the foregoing embodiments, those skilled in the art can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.
Claims
1. A fully automated chemiluminescence immunoassay analyzer, characterized in that: The analyzer includes a main housing (1) and a front housing (3). The front housing (3) is located on the side of the main housing (1). The main housing (1) is equipped with a reaction plate (14). The reaction plate (14) is surrounded by a conveying assembly (12), a sampling assembly (13), a gripper assembly (15), a photometric assembly (16), a mixing assembly (17), and a magnetic separation assembly (18). The front housing (3) is equipped with a display screen (2). The front housing (3) has an opening. A cover plate (31) is located above the opening. The front housing (3) is equipped with a reagent processing unit (32). The reagent processing unit (32) has automatic isolation and temperature control functions. The reagent processing unit (32) includes a sample box (321), an isolation component is provided above the sample box (321), a placement cavity is provided at the upper end of the sample box (321), a control cavity is provided at the lower end of the sample box (321), a storage component is provided inside the placement cavity, and a driving component and a cooling component are provided inside the control cavity. The drive assembly includes a transposition motor (328) and a transmission frame (329). One end of the transmission frame (329) is connected to the storage assembly, and the other end of the transmission frame (329) is connected to the bottom of the sample box (321) through an angle detection element (3291). The transposition motor (328) and the transmission frame (329) are connected through a gear assembly. One end of the refrigeration assembly is connected to the external environment through a filter, and the other end of the refrigeration assembly is connected to the placement chamber through a solenoid valve. The sample box (321) is also equipped with a collaborative component inside, and the isolation component and the driving component are connected through the collaborative component; The collaborative component includes a collaborative frame (3253) and a second electromagnet (3292). The collaborative frame (3253) is located on the inner side of the placement cavity, and the second electromagnet (3292) is located on the upper inner side of the control cavity. The collaborative frame (3253) is connected to the movable cover (325), and the end of the collaborative frame (3253) near the second electromagnet (3292) is made of ferromagnetic material. The second electromagnet (3292) is connected to the transmission frame (329) through a bracket.
2. The fully automated chemiluminescence immunoassay analyzer according to claim 1, characterized in that: A hopper (11) is provided above the main housing (1), and the hopper (11) is aligned with the inlet end of the conveying assembly (12). The conveying assembly (12) has an automatic sorting function.
3. The fully automated chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The isolation assembly includes a fixed cover (322), a mounting bracket (323), and a movable cover (325). The inner walls of the fixed cover (322) and the movable cover (325) are coated with a heat insulation layer. The mounting bracket (323) is fixedly installed above the side of the front housing (3). An isolation motor (3231) is installed inside the mounting bracket (323). The fixed cover (322) is fixedly installed above the sample box (321). The movable cover (325) is movably installed inside the fixed cover (322). The isolation motor (3231) and the movable cover (325) are connected by a linkage assembly.
4. The fully automated chemiluminescence immunoassay analyzer according to claim 3, characterized in that: The fixed cover (322) is provided with a first through hole (3221), the movable cover (325) is provided with a second through hole (3251), and the mounting bracket (323) is also provided with a fan (3233). The air inlet of the fan (3233) is connected to the first through hole (3221) through a conduit (3234), and the fan blades inside the fan (3233) are connected to the main shaft of the isolation motor (3231).
5. The fully automated chemiluminescence immunoassay analyzer according to claim 3, characterized in that: The linkage component includes a first electromagnet (3232) and a permanent magnet (3252). The permanent magnet (3252) is embedded in the lower center of the movable cover (325). The first electromagnet (3232) is located below the permanent magnet (3252) and is connected to the main shaft of the isolation motor (3231).
6. The fully automated chemiluminescence immunoassay analyzer according to claim 1, characterized in that: The storage component includes a sample tray (327), on which several sets of support racks (324) are provided. Each set of support racks (324) contains several reagent bottles (3241). A sample rack (326) is provided between two adjacent sets of support racks (324), and each sample rack (326) has three sample positions.
Citation Information
Patent Citations
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CN110873803A
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