Efficient soothing and anti-allergy plant composite extract as well as preparation method and application thereof
By using a compound extract of Gentiana macrophylla, Gentiana scabra, Swertia serratifolia, Glycyrrhiza uralensis, and Centella asiatica, combined with a specific processing technique, the instability of plant anti-allergy agents and the accumulation of heavy metals have been solved, achieving a highly effective soothing and anti-allergy effect, suitable for daily chemical products.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- Filing Date
- 2025-12-23
- Publication Date
- 2026-04-07
AI Technical Summary
Existing plant-derived anti-allergy agents have problems such as complex ingredients, large batch-to-batch variations, many natural impurities, and accumulation of pesticide residues and heavy metals, which can lead to skin damage and instability.
The compound extract of Gentiana macrophylla, Gentiana scabra, Swertia japonica, Glycyrrhiza uralensis and Centella asiatica is used, combined with technologies such as citric acid aqueous solution washing, flocculant flocculation, ceramic membrane filtration, biological purification and nanofiltration to remove heavy metals and impurities, and natural chelating agents are added to improve stability.
It effectively removes heavy metals and impurities, improves product stability, reduces skin damage, and enhances anti-inflammatory and soothing effects. It is suitable for preparing daily chemical products such as facial mask liquids, gels, and creams.
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Abstract
Description
Technical Field
[0001] This application relates to the technical field of daily chemical products, and in particular to a highly effective soothing and anti-allergic plant compound extract, its preparation method, and its application. Background Technology
[0002] As people increasingly pursue a higher quality of life, the use of plant-derived allergens is growing. Compared to synthetic allergens, plant-derived allergens are safer, as they are free from the influence of impurities such as substances from the synthesis process and isomers of the products. However, plant-derived allergens also have their own drawbacks. First, plant-based raw materials have complex compositions, especially compound plant-based allergens, which generally lack a clear dose-response relationship, resulting in significant batch-to-batch variations. Second, plant-based allergens contain many natural impurities, such as inactive sugars, proteins, inorganic salts, and essential oils, which can cause discoloration, allergies, darkening of color, and instability. Third, plant-derived allergens are also accompanied by the accumulation of small amounts of pesticide residues and heavy metals, which can damage the skin with continued use. Summary of the Invention
[0003] To reduce damage to the skin, this application provides a highly effective soothing and anti-allergic plant compound extract, its preparation method, and its application.
[0004] In the first aspect, this application provides a highly effective soothing and anti-allergic plant compound extract, which adopts the following technical solution: a highly effective soothing and anti-allergic plant compound extract, wherein the raw materials of the highly effective soothing and anti-allergic plant compound extract include the following components in parts by weight: Gentiana macrophylla 11-30 parts, Gentiana scabra 57-65 parts, Swertia serratifolia 5-10 parts, Glycyrrhiza uralensis 3-5 parts, and Centella asiatica 2-4 parts.
[0005] By adopting the above technical solutions, licorice can enhance its anti-inflammatory and soothing effects, while centella asiatica contains asiaticoside, which can promote skin repair and barrier function. Therefore, the combination of the two reduces damage to the skin.
[0006] Secondly, this application provides a method for preparing a highly effective soothing and anti-allergic plant compound extract, which employs the following technical solution: A method for preparing a highly effective soothing and anti-allergic plant compound extract includes the following steps: Washing: Rinse the crushed Gentiana macrophylla and Gentiana scabra with a citric acid aqueous solution with a pH of 4-5 quickly 2-3 times at room temperature to obtain the washed raw material; Extraction: The washed raw materials, swert sprouts, licorice, and centella asiatica were subjected to external circulation extraction to obtain an extract; Flocculation: Add flocculant to the extract, stir to flocculate, and obtain flocculent liquid; Filtration: The flocculant is filtered through a ceramic membrane to remove the filter residue and obtain the filtrate. Purification: The filtrate is subjected to biological purification treatment in a purification tank to obtain purified liquid; Ultrafiltration: The purified liquid is subjected to ultrafiltration to obtain the ultrafiltration permeate; Nanofiltration: The ultrafiltration permeate is subjected to nanofiltration to obtain a nanofiltration concentrate. Preparation: Propylene glycol or butylene glycol, along with a natural chelating agent, are added to the nanofiltration concentrate to obtain a highly effective soothing and anti-allergic plant compound extract.
[0007] By adopting the above technical solution, the plant surface is first cleaned with a citric acid aqueous solution, which can effectively wash away dust, some water-soluble inorganic salts and attached heavy metals. This can remove some of the most easily introduced heavy metals in advance, reducing the burden of subsequent purification. In the final preparation, a natural chelating agent is added. The chelating agent can complex with trace amounts of metal ions that may remain in the product, effectively preventing them from catalyzing the oxidation of oils or the degradation of components during storage, thereby greatly improving the chemical stability of the product.
[0008] In one specific implementation scheme, the solvent in the extraction step is water, the extraction temperature is 95-100℃, and the extraction time is 2-3 hours.
[0009] In one specific implementation, the flocculant in the flocculation step comprises a mixture of chitosan, sodium alginate, and food-grade polyaluminum chloride; and the temperature is 40-50°C, and the time is 30-60 minutes.
[0010] By adopting the above technical solution, a composite flocculant composed of chitosan, sodium alginate, and food-grade polyaluminum chloride is used. Chitosan and sodium alginate enhance the adsorption of heavy metals and proteins, while food-grade polyaluminum chloride has a better flocculation effect on soluble microparticles and some heavy metal ions.
[0011] In one specific implementation, the filtration step involves a ceramic membrane with a pore size of 100 nm and a pressure of 1-2 bar.
[0012] By adopting the above technical solution, the pore size and filtration pressure of the ceramic membrane are further limited, which can more effectively remove macromolecular impurities and particulate matter.
[0013] In one specific implementation scheme, the purification step is as follows: Modified porous zeolite is added to a purification tank. Ammonium nitrate, dipotassium hydrogen phosphate, ferrous citrate, disodium EDTA, and L-cysteine are added to purified water as a culture medium. The composite algal seed solution is inoculated into the freshly prepared culture medium, and sodium selenate is added simultaneously. Then, the mixture is added to the purification tank containing the modified porous zeolite for enrichment cultivation. After cultivation, the culture medium is drained, the purification tank is rinsed twice with purified water, the purified water is drained, forming a purification system. Within 2 hours, filtrate is introduced for biological purification treatment to obtain the purified solution.
[0014] By adopting the above technical solution, selenate can be converted into selenium-containing proteins with strong affinity for heavy metals within algal cells. Disodium ethylenediaminetetraacetate combines with L-cysteine to form stable water-soluble complexes with various heavy metal ions, changing their free state and making them easier for subsequent microorganisms and zeolites to capture, thereby improving the treatment effect of heavy metals.
[0015] In one specific implementation, the purification step includes a mixture of Chlorella seed solution and Saccharomyces cerevisiae.
[0016] By adopting the above technical solution, the combination of Chlorella and Saccharomyces cerevisiae forms a complementary function in adsorbing heavy metals and removing conventional ions.
[0017] In one specific implementation, the method for preparing the modified porous zeolite includes the following steps: Porous zeolite is impregnated in a sodium chloride solution with a mass concentration of 4%-6%, treated at 55-65℃ for 1-3 hours, rinsed until neutral, and dried to obtain modified porous zeolite.
[0018] By adopting the above technical solution, zeolite is pretreated with sodium chloride solution to significantly increase its ion exchange capacity for cations such as calcium and magnesium. Then, as a carrier for microorganisms, its huge specific surface area and ion exchange capacity can pre-capture and enrich heavy metals and ammonium ions in water, significantly improving the adsorption and purification effect of microorganisms attached to it.
[0019] In one specific implementation, the natural chelating agent includes one of sodium phytate and citric acid.
[0020] Thirdly, the application of the highly effective soothing and anti-allergic plant compound extract provided in this application adopts the following technical solution: An application of a highly effective soothing and anti-allergic plant compound extract, wherein the highly effective soothing and anti-allergic plant compound extract can be used to prepare daily chemical products such as facial mask liquid, gel, and cream.
[0021] In summary, this application includes at least one of the following beneficial technical effects: 1. In this application, licorice can enhance anti-inflammatory and soothing effects, and centella asiatica contains asiaticoside, which can promote skin repair and barrier function. Therefore, by using the combination of the two, damage to the skin is reduced. 2. The method in this application first uses a citric acid aqueous solution for cleaning, which can effectively wash away dust, some water-soluble inorganic salts and attached heavy metals on the plant surface. This can remove some of the most easily introduced heavy metals in advance, reducing the burden of subsequent purification. Furthermore, in the final preparation, a natural chelating agent is added. The chelating agent can complex with trace amounts of metal ions that may remain in the product, effectively preventing them from catalyzing the oxidation of oils or the degradation of components during storage, thereby greatly improving the chemical stability of the product. 3. Applications in this application: Highly effective soothing and anti-allergic plant compound extracts can be used to prepare daily chemical products such as facial mask liquids, gels, and creams. Detailed Implementation
[0022] The present application will be further described in detail below with reference to the embodiments.
[0023] All raw materials used in the examples are commercially available.
[0024] Preparation Example Preparation Example 1 Preparation Example 1 provides a method for preparing modified porous zeolite, comprising the following steps: The porous zeolite was immersed in a 4% sodium chloride solution, treated at 55°C for 3 hours, rinsed until neutral, and dried to obtain the modified porous zeolite.
[0025] Preparation Example 2 Preparation Example 2 provides a method for preparing modified porous zeolite, comprising the following steps: The porous zeolite was impregnated in a 5% sodium chloride solution and treated at 60°C for 2 hours. After rinsing until neutral, it was dried to obtain the modified porous zeolite.
[0026] Preparation Example 3 Preparation Example 3 provides a method for preparing modified porous zeolite, comprising the following steps: The porous zeolite was impregnated in a 6% sodium chloride solution, treated at 65°C for 1 hour, rinsed until neutral, and dried to obtain modified porous zeolite. Example
[0027] Example 1 Example 1 provides a method for preparing a highly effective soothing and anti-allergic plant compound extract, comprising the following steps: Washing: 11 kg of crushed Gentiana macrophylla and 65 kg of Gentiana scabra were quickly rinsed twice at room temperature with a citric acid aqueous solution of pH 4 to obtain the washed raw material. Extraction: The washed raw materials, 10 kg of swert sprouts, 5 kg of licorice, and 4 kg of centella asiatica were subjected to external circulation extraction to obtain an extract; the solvent was water, the extraction temperature was 95℃, and the extraction time was 3 hours. Flocculation: Add flocculant to the extract and stir at 40℃ for 60 min at a stirring speed of 50 rpm to obtain flocculent liquid; wherein the flocculant is a mixture of chitosan, sodium alginate and food-grade polyaluminum chloride, with the amount of chitosan added being 0.1 w / w‰, the amount of sodium alginate added being 0.05 w / w‰, and the amount of food-grade polyaluminum chloride added being 0.05 w / w‰; Filtration: The flocculant is filtered through a ceramic membrane to remove the filter residue and obtain the filtrate; the ceramic membrane has a pore size of 100 nm and a pressure of 1 bar. Purification: Modified porous zeolite from Preparation Example 1 was added to a purification tank, with the volume of the modified porous zeolite being 70% of the tank's volume. Ammonium nitrate, dipotassium hydrogen phosphate, ferrous citrate, disodium EDTA, and L-cysteine were added to purified water as a culture medium. The composite algal culture was inoculated into the freshly prepared culture medium, along with sodium selenate. This was then added to the purification tank containing the modified porous zeolite for enrichment cultivation. The cultivation temperature was 28℃, pH 5, and light intensity 8000 lx. Compressed air was introduced three times daily, per m³. 3 1m each time the can is used 3 The culture was carried out at a rate of 1000 m / min for 4 min, and the culture time was 4 min. After 3 consecutive days of cultivation, the culture medium was drained, and the purification tank was rinsed twice with purified water. The purified water was then drained to form a purification system. Filtrate was introduced for biological purification within 2 hours to obtain the purified solution. The purified solution contained 75 ppm ammonium nitrate, 5 ppm dipotassium hydrogen phosphate, 0.3 ppm ferrous citrate, 15 ppm disodium EDTA, and 5 ppm L-cysteine. The composite algal culture medium consisted of a mixture of Chlorella culture medium and Saccharomyces cerevisiae, with a weight ratio of 2:0.015. The volume ratio of the composite algal culture medium to the culture medium was 1:2. Sodium selenate was added at 1.5 ppm. Ultrafiltration: The purified solution was passed through an ultrafiltration membrane to obtain the ultrafiltration permeate. The ultrafiltration membrane had a pore size of 5000–10000 Daltons, a pressure of 4 bar, and a temperature ≤50℃. Nanofiltration: The ultrafiltration permeate is passed through a nanofiltration membrane to obtain a nanofiltration concentrate. The nanofiltration membrane has a pore size of 500 to 1000 Daltons, a pressure of 7 bar, and a temperature of ≤50℃. Preparation: Propylene glycol and a natural chelating agent were added to the nanofiltration concentrate to obtain a highly effective soothing and anti-allergic plant compound extract; wherein the amount of propylene glycol added was 50 w / w%; the amount of natural chelating agent added was 0.1%, and the natural chelating agent was citric acid.
[0028] Example 2 The difference between Example 2 and Example 1 is that the washing process involves rinsing 20 kg of crushed Gentiana macrophylla and 61.5 kg of Gentiana scabra with citric acid solution at pH 4 twice at room temperature to obtain the washed raw material. Extraction: The washed raw materials, 7.5 kg of swert sprouts, 4 kg of licorice, and 3 kg of centella asiatica were subjected to external circulation extraction to obtain an extract; the solvent was water, the extraction temperature was 95℃, and the extraction time was 3 h; the remaining steps were the same as in Example 1.
[0029] Example 3 The difference between Example 3 and Example 1 is that the washing process involves rinsing 30 kg of crushed Gentiana macrophylla and 57 kg of Gentiana scabra with citric acid solution at pH 4 twice at room temperature to obtain washed raw materials. Extraction: The washed raw materials, 5 kg of swert sprouts, 3 kg of licorice, and 2 kg of centella asiatica were subjected to external circulation extraction to obtain an extract; the solvent was water, the extraction temperature was 95℃, and the extraction time was 3 hours; the remaining steps were the same as in Example 1.
[0030] Example 4 The difference between Example 4 and Example 2 is as follows: Extraction: 7.5 kg of water-washed raw materials, 4 kg of swert sprouts, 4 kg of licorice, and 3 kg of centella asiatica were subjected to external circulation extraction to obtain an extract; the solvent was water, the extraction temperature was 98℃, and the extraction time was 2.5 h; Flocculation: A flocculant was added to the extract, and flocculation was carried out at 45℃ with stirring for 45 min at a stirring speed of 50 rpm to obtain a flocculant; the flocculant consisted of a mixture of chitosan, sodium alginate, and food-grade polyaluminum chloride, with the amount of chitosan added being 0.1 w / w‰, the amount of sodium alginate added being 0.05 w / w‰, and the amount of food-grade polyaluminum chloride added being 0.05 w / w‰; the remaining steps were the same as in Example 2.
[0031] Example 5 The difference between Example 5 and Example 2 is as follows: Extraction: 7.5 kg of water-washed raw materials, 4 kg of swert sprouts, 4 kg of licorice, and 3 kg of centella asiatica were subjected to external circulation extraction to obtain an extract; the solvent was water, the extraction temperature was 100℃, and the extraction time was 2 hours; Flocculation: A flocculant was added to the extract, and flocculation was carried out at 50℃ with stirring for 30 minutes at a stirring speed of 50 rpm to obtain a flocculent liquid; the flocculant consisted of a mixture of chitosan, sodium alginate, and food-grade polyaluminum chloride, with the amount of chitosan added being 0.1 w / w‰, the amount of sodium alginate added being 0.05 w / w‰, and the amount of food-grade polyaluminum chloride added being 0.05 w / w‰; the remaining steps were the same as in Example 2.
[0032] Example 6 The difference between Example 6 and Example 4 is the purification process: Modified porous zeolite from Preparation Example 1 was added to the purification tank, with the volume of the modified porous zeolite being 70% of the tank's volume. Ammonium nitrate, dipotassium hydrogen phosphate, ferrous citrate, disodium EDTA, and L-cysteine were added to purified water as the culture medium. Chlorella seed culture was inoculated into the freshly prepared culture medium, along with sodium selenate. This was then added to the purification tank containing the modified porous zeolite for enrichment cultivation. The cultivation temperature was 28°C, pH 5, light intensity 8000 lx, and compressed air was introduced three times daily. 3 1m each time the can is used 3 The culture medium was continuously cultured for 3 days at a rate of 1 / min for 4 minutes. After that, the culture medium was drained, and the purification tank was rinsed twice with purified water. The purified water was then drained to form a purification system. The filtrate was then introduced for biological purification within 2 hours to obtain the purified solution. The amount of ammonium nitrate added to the purified water was 75 ppm, dipotassium hydrogen phosphate was 5 ppm, ferrous citrate was 0.3 ppm, disodium ethylenediaminetetraacetate was 15 ppm, and L-cysteine was 5 ppm. The volume ratio of Chlorella seed culture to culture medium was 1:2. Sodium selenate was added at 1.5 ppm. The remaining steps were the same as in Example 4.
[0033] Example 7 The difference between Example 7 and Example 4 is the purification process: porous zeolite is added to the purification tank, with the volume of porous zeolite being 70% of the tank's volume; ammonium nitrate, dipotassium hydrogen phosphate, ferrous citrate, disodium EDTA, and L-cysteine are added to purified water as the culture medium; the composite algal culture is inoculated into the freshly prepared culture medium, and sodium selenate is added simultaneously, followed by enrichment cultivation in the purification tank containing modified porous zeolite; the cultivation temperature is 28℃, pH is 5, light intensity is 8000 lx, and compressed air is introduced 3 times per day, per m 3 1m each time the can is used 3 The culture was carried out at a rate of 1 / min for 4 minutes, and the culture medium was drained after 3 consecutive days. The purification tank was rinsed twice with purified water, and the purified water was drained to form a purification system. The filtrate was introduced for biological purification within 2 hours to obtain the purified solution. The amount of ammonium nitrate added to the purified water was 75 ppm, the amount of dipotassium hydrogen phosphate was 5 ppm, the amount of ferrous citrate was 0.3 ppm, the amount of disodium ethylenediaminetetraacetate was 15 ppm, and the amount of L-cysteine was 5 ppm. The compound algal seed solution consisted of a mixture of Chlorella seed solution and Saccharomyces cerevisiae, with a weight ratio of Chlorella seed solution to Saccharomyces cerevisiae of 2:0.015. The volume ratio of the compound algal seed solution to the culture medium was 1:2. The amount of sodium selenate added was 1.5 ppm. The remaining steps were the same as in Example 4.
[0034] Comparative Example Comparative Example 1 The difference between Comparative Example 1 and Example 1 is that the extraction was carried out by external circulation extraction of 24 kg of water-washed raw material and swert sprouts to obtain an extract; the solvent was water, the extraction temperature was 95°C, and the extraction time was 3 hours; the remaining steps were the same as in Example 1.
[0035] Application examples Application Example 1 Application Example 1 provides a method for preparing a cream, comprising the following steps: Add 60 kg of deionized water to the main pot, turn on the stirrer, slowly and evenly add 0.2 kg of xanthan gum and 1.0 kg of ammonium acryloyl dimethyl taurate / VP copolymer, stir until completely dispersed and uniform, add 4 kg of glycerol and 3 kg of butylene glycol in sequence, slowly add 5 kg of the high-efficiency soothing and anti-allergic plant complex extract from Example 1, stir until uniformly mixed, raise the temperature to 83°C, and keep stirring at this temperature for about 15 minutes to obtain phase A; In an oil phase pot, add 3 kg of cetearyl alcohol olive oil ester, 2 kg of polydimethylsiloxane, 5 kg of squalane, 2 kg of shea butter, 1.5 kg of cetearyl alcohol, 1.5 kg of PEG-100 stearate, and 1 kg of glyceryl stearate in sequence; heat to 83°C and stir until all oil phase components are completely dissolved to obtain phase B; The insulated phase B is slowly added to the main pot of phase A through a filter screen. Medium-speed stirring is started at 2700 rpm and homogenized for 3 minutes to form a uniform and delicate emulsion. After homogenization, the mixture is switched to scraping and stirring, and the temperature is slowly reduced. When the temperature of the paste drops to 45°C, 1.5 kg of dipropylene glycol, 1 kg of panthenol, 0.3 kg of tocopheryl acetate, 0.5 kg of phenoxyethanol, and 0.3 kg of ethylhexylglycerin are slowly added. The mixture is stirred and homogenized for 4 minutes, and then stirred and cooled to 36°C. The pH of the paste is adjusted to a slightly acidic range of 6.0 with a 10% triethanolamine aqueous solution to obtain the cream.
[0036] Application Example 2 The difference between Application Example 2 and Application Example 1 is that the highly effective soothing and anti-allergic plant compound extract used in Example 2 is selected, while the remaining steps are the same as in Application Example 1.
[0037] Application Example 3 The difference between Application Example 3 and Application Example 1 is that the highly effective soothing and anti-allergic plant compound extract used in Example 3 is selected, while the remaining steps are the same as in Application Example 1.
[0038] Application Example 4 The difference between Application Example 4 and Application Example 1 is that the highly effective soothing and anti-allergic plant compound extract used in Application Example 4 is selected, while the remaining steps are the same as in Application Example 1.
[0039] Application Example 5 The difference between Application Example 5 and Application Example 1 is that the highly effective soothing and anti-allergic plant compound extract used in Application Example 5 is selected, while the remaining steps are the same as in Application Example 1.
[0040] Application Example 6 The difference between Application Example 6 and Application Example 1 is that the highly effective soothing and anti-allergic plant compound extract used in Application Example 6 is selected, while the remaining steps are the same as in Application Example 1.
[0041] Application Example 7 The difference between Application Example 7 and Application Example 1 is that the highly effective soothing and anti-allergic plant compound extract used in Example 7 is selected, while the remaining steps are the same as in Application Example 1.
[0042] Comparative Application Examples Comparative Application Example 1 The difference between Application Example 1 and Application Example 2 is that the highly effective soothing and anti-allergic plant compound extract used in Application Example 1 is selected, while the remaining steps are the same as in Application Example 1.
[0043] Performance testing Heavy metal testing: The total content of lead, arsenic, mercury, and cadmium in the highly effective soothing and anti-allergic plant compound extracts in each example and comparative example was tested in accordance with the 2015 edition of the "Cosmetic Safety Technical Specifications".
[0044] Anti-allergy and anti-itch: Eighty subjects with sensitive skin, aged 25-40, were selected and divided into eight groups of ten, corresponding to application examples 1-7 and control application example 1, respectively. When the skin felt sensitive, red, or itchy, the creams in the application examples and control application examples could be applied to the affected areas at any time, with 0.8g used each time. After two months, the results were collected and the product was scored. The average score for each group was taken. The scoring standard was 1-10 points. The higher the score, the better the anti-allergy and anti-itch effect of the product.
[0045] Table 1 Performance test results of highly effective soothing and anti-allergic plant compound extracts sample Metal content (ppm) Example 1 0.45 Example 2 0.48 Example 3 0.51 Example 4 0.42 Example 5 0.40 Example 6 0.58 Example 7 0.75 Comparative Example 1 1.20 Table 2 Performance test results of the cream Combining Table 2, Application Example 1, and Comparative Application Example 1, the cream in Application Example 1 showed better anti-allergic and antipruritic effects. This indicates that when preparing a highly effective soothing and anti-allergic plant compound extract, adding licorice and centella asiatica to the raw materials can enhance the anti-inflammatory and soothing effects of licorice and promote skin repair and barrier function of centella asiatica. Therefore, the anti-allergic and antipruritic efficacy of the cream is improved.
[0046] Based on Table 2 and Application Examples 1-3, it can be seen that when preparing a highly effective soothing and anti-allergic plant compound extract, following the ratio of raw materials in Examples 1-3 yields a more effective soothing and anti-allergic plant compound extract.
[0047] Based on Table 2, Application Example 2, Application Example 4, and Application Example 5, it can be seen that when preparing a highly effective soothing and anti-allergic plant compound extract, following the preparation conditions in Examples 2, 4, and 5 yields a more effective soothing and anti-allergic plant compound extract.
[0048] Based on Table 1, Examples 4 and 6, the metal content of the highly efficient soothing and anti-allergic plant compound extract in Example 4 is relatively low. This indicates that when preparing the highly efficient soothing and anti-allergic plant compound extract, the use of a compound algal solution composed of Chlorella seed solution and Saccharomyces cerevisiae for biological purification of the filtrate is effective in treating porous zeolite, thereby improving the adsorption effect on metals in the filtrate.
[0049] Based on Table 1, Examples 4 and 7, the metal content of the highly efficient soothing and anti-allergic plant compound extract in Example 4 is relatively low. This indicates that when preparing the highly efficient soothing and anti-allergic plant compound extract, porous zeolite treated with sodium chloride solution was selected for the biological purification of the filtrate. The zeolite was pretreated with sodium chloride solution, which significantly improved its ion exchange capacity for cations such as calcium and magnesium. Then, as a carrier for microorganisms, its huge specific surface area and ion exchange capacity can pre-capture and enrich heavy metals and ammonium ions in the water, thereby further improving the adsorption effect on metals in the filtrate.
[0050] This specific embodiment is merely an explanation of this application and is not intended to limit it. After reading this specification, those skilled in the art can make modifications to this embodiment without contributing any inventive step, but such modifications are protected by patent law as long as they fall within the scope of the claims of this application.
Claims
1. A highly effective soothing and anti-allergic plant compound extract, characterized in that: The raw materials of the highly effective soothing and anti-allergic plant compound extract include the following components in parts by weight: Gentiana macrophylla 11-30 parts, Gentiana scabra 57-65 parts, Swertia serratifolia 5-10 parts, Glycyrrhiza uralensis 3-5 parts, and Centella asiatica 2-4 parts.
2. A method for preparing the highly effective soothing and anti-allergic plant compound extract as described in claim 1, characterized in that: Includes the following steps: Washing: Rinse the crushed Gentiana macrophylla and Gentiana scabra with a citric acid aqueous solution with a pH of 4-5 quickly 2-3 times at room temperature to obtain the washed raw material; Extraction: The washed raw materials, swert sprouts, licorice, and centella asiatica were subjected to external circulation extraction to obtain an extract; Flocculation: Add flocculant to the extract, stir to flocculate, and obtain flocculent liquid; Filtration: The flocculant is filtered through a ceramic membrane to remove the filter residue and obtain the filtrate. Purification: The filtrate is subjected to biological purification treatment in a purification tank to obtain purified liquid; Ultrafiltration: The purified liquid is subjected to ultrafiltration to obtain the ultrafiltration permeate; Nanofiltration: The ultrafiltration permeate is subjected to nanofiltration to obtain a nanofiltration concentrate. Preparation: Propylene glycol or butylene glycol, along with a natural chelating agent, are added to the nanofiltration concentrate to obtain a highly effective soothing and anti-allergic plant compound extract.
3. The preparation method of a highly efficient soothing and anti-allergic plant compound extract according to claim 2, characterized in that: In the extraction step, the solvent is water, the extraction temperature is 95-100℃, and the extraction time is 2-3 hours.
4. The preparation method of a highly efficient soothing and anti-allergic plant compound extract according to claim 2, characterized in that: In the flocculation step, the flocculant comprises a mixture of chitosan, sodium alginate, and food-grade polyaluminum chloride; and the temperature is 40-50℃, and the time is 30-60 minutes.
5. The method for preparing a highly efficient soothing and anti-allergic plant compound extract according to claim 2, characterized in that: In the filtration step, the ceramic membrane has a pore size of 100 nm and a pressure of 1-2 bar.
6. The method for preparing a highly efficient soothing and anti-allergic plant compound extract according to claim 2, characterized in that: The purification steps are as follows: Modified porous zeolite is added to the purification tank, and ammonium nitrate, dipotassium hydrogen phosphate, ferrous citrate, disodium EDTA, and L-cysteine are added to purified water as a culture medium. The composite algal seed solution is inoculated into the freshly prepared culture medium, and sodium selenate is added at the same time. Then, it is added to the purification tank containing modified porous zeolite for rich cultivation. After the cultivation is completed, the culture medium is discharged, the purification tank is rinsed twice with purified water, the purified water is drained, a purification system is formed, and the filtrate is introduced for biological purification treatment within 2 hours to obtain the purified solution.
7. The method for preparing a highly effective soothing and anti-allergic plant compound extract according to claim 6, characterized in that: In the purification step, the compound algae seed solution includes a mixture of Chlorella seed solution and Saccharomyces cerevisiae.
8. The method for preparing a highly effective soothing and anti-allergic plant compound extract according to claim 6, characterized in that: The preparation method of the modified porous zeolite includes the following steps: The porous zeolite was immersed in a sodium chloride solution with a mass concentration of 4%-6% and treated at 55-65℃ for 1-3 hours. After rinsing until neutral, it was dried to obtain modified porous zeolite.
9. The method for preparing a highly effective soothing and anti-allergic plant compound extract according to claim 2, characterized in that: The natural chelating agent includes one of sodium phytate and citric acid.
10. The application of a highly effective soothing and anti-allergic plant compound extract, characterized in that: The highly effective soothing and anti-allergic plant compound extract as described in claim 1 can be used to prepare daily chemical products such as facial mask liquid, gel, and cream.