Mild disinfection wet tissue as well as preparation method and application thereof

Abstract

The invention provides a mild disinfection wet tissue as well as a preparation method and application thereof. The disinfection wet tissue comprises wet tissue liquid and a carrier, the wet tissue liquid comprises the following components: a redox potential regulator, antibacterial peptide, a chelating agent and deionized water; the redox potential regulator comprises any one or a combination of at least two of hydrogen peroxide, chitosan and polyvinylpyrrolidone. The redox potential regulator and the antibacterial peptide are added on the basis of the formula design of the disinfection wet tissue, the redox potential regulator can greatly improve the sterilization effect of the antibacterial agent in the formula, the broad-spectrum antibacterial property of the whole formula can be improved by adding the antibacterial peptide, and the effects of moisturizing, relieving and the like can be brought to the product; the mildness of the formula is further enhanced.

Description

Technical Field

[0001] This invention belongs to the field of daily necessities technology, specifically relating to a mild disinfecting wipe, its preparation method, and its application. Background Technology

[0002] Disinfecting wipes are products made from non-woven fabrics, woven fabrics, dust-free paper, or other raw materials, using purified water and appropriate amounts of bactericides and other raw materials. They have cleaning and disinfecting properties and are suitable for the human body, general object surfaces, medical device surfaces, and other object surfaces. Currently, they are widely used for cleaning and disinfection in hospitals, as well as for the whole-body cleaning and disinfection of long-term bedridden patients. They have advantages such as being convenient to use, ready to use immediately, and effectively preventing cross-infection.

[0003] CN113244147A discloses a composite sterilizing disinfectant wipe and its preparation method. This invention involves adding ethanol, benzalkonium chloride, and polyhexamethylene guanidine during the preparation of the disinfectant wipe. Ethanol can destroy bacterial cell walls, denature bacterial cell proteins, hinder metabolism, and lead to bacterial inactivation. Benzalkonium chloride is a cationic surfactant that, through hydrolysis, produces quaternary ammonium cations that adsorb electronegative bacteria, altering cell membrane permeability, causing cytoplasm loss, and preventing metabolism, thereby inactivating bacteria. Polyhexamethylene guanidine is a cationic polymer that alters cell membrane permeability by dissolving lipids, hindering normal bacterial metabolic activities and causing inactivation. The three components have good compatibility and, after compounding, form a disinfectant solution. The disinfectant wipe, made with a composite non-woven fabric as a carrier, is a dual-purpose disinfectant wipe that serves both human body cleaning and disinfection and object surface cleaning and disinfection, achieving a two-in-one function.

[0004] CN115068349A discloses an antibacterial disinfectant wipe, composed of an antibacterial disinfectant soaking solution and a wipe substrate. The antibacterial disinfectant soaking solution, by mass percentage, comprises: 10-30% polyhydroxysilyl quaternary ammonium salt compound, 0.1-3% surfactant, 0.5-5% dispersant, 0.05-1.5% pH adjuster, and the balance being RO purified water. Adding the antibacterial disinfectant soaking solution and the wipe substrate at a specific mass ratio forms an antibacterial disinfectant wipe. The preparation method is simple, and it exhibits stable and long-lasting disinfection and continuous inhibition of microbial growth, showing broad application prospects in antibacterial agents, antimicrobial agents, antibacterial wipes, and antibacterial medical materials.

[0005] The disinfectants in existing disinfectant wipes mainly include quaternary ammonium salt bactericides. However, when quaternary ammonium salt bactericides are added to the carrier, the effective components of the squeezed liquid that exert the actual bactericidal effect immediately decrease significantly, resulting in a significant reduction in the bactericidal efficacy of the disinfectant wipes. Therefore, it is often necessary to increase the proportion of bactericide to compensate for this effect. However, using too much quaternary ammonium salt bactericide can lead to high irritation and safety concerns. Therefore, there is an urgent need to provide a product with better disinfection effect and gentler, safer use to meet application requirements. Summary of the Invention

[0006] To address the shortcomings of existing technologies, this invention provides a mild disinfecting wipe, its preparation method, and its application.

[0007] To achieve this objective, the present invention employs the following technical solution:

[0008] In a first aspect, the present invention provides a mild disinfecting wipe, the disinfecting wipe comprising a wipe liquid and a carrier;

[0009] The components of the wet wipe liquid include an oxidation-reduction potential modifier, antimicrobial peptides, chelating agents, and deionized water;

[0010] The redox potential modifier includes any one or a combination of at least two of hydrogen peroxide, deacetylated chitosan, or polyvinylpyrrolidone.

[0011] This invention uses an ORP regulator (oxidation-reduction potential regulator) as a key functional ingredient. By eliminating all reducing agents in the wet wipe formulation system, the ORP value of the formulation system reaches above 150-200 mV, disrupting the survival conditions of bacteria and fungi and greatly improving the bactericidal effect of the bactericide in the formulation. Because the addition of the ORP regulator enhances the bactericidal efficacy of the antibacterial agent, the formulation design of disinfectant wipes can achieve the required bactericidal effect with a single antibacterial agent. Since the amount of antibacterial agent added can be significantly reduced, the mildness of the formulation is significantly improved. Simultaneously, to further ensure mildness, the antibacterial agent selected is an antimicrobial peptide. Antimicrobial peptides are positively charged cationic molecules that, under a certain membrane potential, can adsorb onto the cell membrane of pathogens, accumulate on the cell membrane surface, and insert into the cell membrane through C-terminal action, forming permeable pores. This causes the cell membrane to lose polarity, leading to the loss of intracellular small molecule solutes (ATP, amino acids, ions, etc.) and the inflow of extracellular water molecules, resulting in the disappearance of the energy difference across the cell membrane, cell autolysis, and death. Antimicrobial peptides readily form a network structure with water molecules in the system, effectively locking in moisture and providing continuous hydration, leaving the skin supple. They also possess anti-inflammatory and soothing properties. Therefore, adding antimicrobial peptides to the formula not only enhances the broad-spectrum antibacterial activity of the entire formula but also provides moisturizing and soothing effects, further improving the formula's gentleness.

[0012] Preferably, the mass ratio of the carrier to the wet wipe liquid is 1:(2.5-4), for example, it can be 1:2.6, 1:2.8, 1:3, 1:3.2, 1:3.4, 1:3.6 or 1:3.8, etc.

[0013] Preferably, the carrier includes any one of nonwoven fabric, woven fabric, or cleanroom paper.

[0014] Preferably, the wet wipe liquid comprises, by weight, 0.01-1 parts of an oxidation-reduction potential modifier (e.g., 0.02 parts, 0.05 parts, 0.08 parts, 0.1 parts, 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, or 0.9 parts, etc.) and 0.5-2 parts of an antimicrobial peptide (e.g., 0.6 parts, 0.7 parts, 0.8 parts, 0.9 parts, 1 part, 1.1 parts, 1. 2 parts, 1.3 parts, 1.4 parts, 1.5 parts, 1.6 parts, 1.7 parts, 1.8 parts or 1.9 parts, etc.), 0.01-0.5 parts of chelating agent (e.g., 0.02 parts, 0.05 parts, 0.08 parts, 0.1 parts, 0.2 parts, 0.3 parts or 0.4 parts, etc.), and 90-99 parts of deionized water (e.g., 91 parts, 92 parts, 93 parts, 94 parts, 95 parts, 96 parts, 97 parts, 98 parts or 99 parts, etc.).

[0015] Preferably, the mass ratio of the redox potential regulator to the antimicrobial peptide is 1:(10-20), for example, it can be 1:11, 1:12, 1:13, 1:14, 1:15, 1:16, 1:17, 1:18 or 1:19, etc.

[0016] Preferably, the redox potential regulator is hydrogen peroxide, deacetylated chitosan, and polyvinylpyrrolidone.

[0017] Preferably, the mass ratio of hydrogen peroxide, deacetylated chitosan and polyvinylpyrrolidone is (20-40):(0.1-2):(1-10).

[0018] "20-40" can be 21, 23, 25, 27, 29, 30, 31, 33, 35, 37 or 39, etc.

[0019] "0.1-2" can be 0.2, 0.3, 0.4, 0.5, 0.6, 0.7, 0.8, 0.9, 1, 1.1, 1.2, 1.3, 1.4, 1.5, 1.6, 1.7, 1.8, or 1.9, etc.

[0020] "1-10" can be 2, 3, 4, 5, 6, 7, 8 or 9, etc.

[0021] Preferably, the antimicrobial peptide comprises lactic acid bacteria fermentation products.

[0022] Preferably, the chelating agent includes any one or a combination of at least two of tetrasodium EDTA, disodium EDTA, or tetrasodium glutamate diacetate.

[0023] Preferably, the wet wipe liquid also includes quaternary ammonium salt bactericide and / or pH adjuster.

[0024] Preferably, the wet wipe liquid composition further includes 0.01-1 parts by weight of quaternary ammonium salt bactericide (e.g., 0.02 parts, 0.04 parts, 0.05 parts, 0.07 parts, 0.09 parts, 0.1 parts, 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, or 0.9 parts, etc.) and 0.01-1 parts by weight of pH adjuster (e.g., 0.02 parts, 0.05 parts, 0.08 parts, 0.1 parts, 0.2 parts, 0.3 parts, 0.4 parts, 0.5 parts, 0.6 parts, 0.7 parts, 0.8 parts, or 0.9 parts, etc.).

[0025] Preferably, the pH adjuster includes citric acid and / or sodium citrate.

[0026] Preferably, the quaternary ammonium salt bactericide includes any one or a combination of two of benzalkonium chloride, benzyl chloride, or dialcyldimethylammonium chloride.

[0027] Preferably, the quaternary ammonium salt bactericide is benzalkonium chloride.

[0028] All the specific point values ​​within the above range can be selected, and will not be elaborated on here.

[0029] Secondly, the present invention provides a method for preparing a mild disinfectant wipe as described in the first aspect, the method comprising:

[0030] (1) A mixture was obtained by mixing deionized water, chelating agent and antimicrobial peptide;

[0031] (2) Add a redox potential regulator to the mixture and mix to obtain a wet wipe solution;

[0032] (3) The carrier is soaked in wet wipe liquid and packaged to obtain the mild disinfectant wipes.

[0033] Preferably, the mixing in step (1) is carried out by stirring, the stirring speed is 30-50 rpm (for example, it can be 31 rpm, 33 rpm, 35 rpm, 37 rpm, 40 rpm, 42 rpm, 45 rpm or 48 rpm, etc.), and the time is 5-10 min (for example, it can be 6 min, 7 min, 8 min or 9 min, etc.).

[0034] Preferably, the mixing in step (2) is carried out by stirring, and the stirring speed is 30-50 rpm (for example, it can be 31 rpm, 33 rpm, 35 rpm, 37 rpm, 40 rpm, 42 rpm, 45 rpm or 48 rpm, etc.), and the time is 8-15 min (for example, it can be 9 min, 10 min, 11 min, 2 min, 13 min or 14 min, etc.).

[0035] Preferably, step (2) further includes adding a quaternary ammonium salt bactericide and / or a pH adjuster.

[0036] All the specific point values ​​within the above range can be selected, and will not be elaborated on here.

[0037] Thirdly, the present invention provides an application of mild disinfecting wipes as described in the first aspect in the preparation of daily necessities.

[0038] Compared with the prior art, the present invention has the following beneficial effects:

[0039] This invention provides a mild disinfectant wipe formulation design concept. The formulation incorporates an ORP regulator and antimicrobial peptides. The ORP regulator eliminates all reducing agents in the wipe formulation system, raising the ORP value to over 150-200 mV, thus disrupting the survival conditions of bacteria and molds and significantly improving the bactericidal effect of the antimicrobial agents in the formulation. The addition of antimicrobial peptides not only increases the broad-spectrum antibacterial activity of the entire formulation but also provides moisturizing and soothing effects, further enhancing the mildness of the formulation. Because the addition of the ORP regulator and antimicrobial peptides reduces the amount of quaternary ammonium salt bactericides required, and the desired effect of disinfectant wipes can be achieved by adding a single bactericide component, this method simplifies the process considerably compared to other existing disinfectant wipe formulations. A simpler formulation ensures greater product mildness. Detailed Implementation

[0040] The technical solution of the present invention will be further illustrated below through specific embodiments. Those skilled in the art should understand that the embodiments described are merely illustrative of the present invention and should not be construed as limiting the invention in any way.

[0041] The antimicrobial peptides used in the embodiments of this invention are all lactic acid bacteria fermentation products, which are derived from Guangdong Liyan Biotechnology Co., Ltd.

[0042] The viscose-polyester spunlace nonwoven fabric was purchased from Hainan Xinlong Nonwoven Co., Ltd.

[0043] The raw materials used in the embodiments or comparative examples of this invention can be used as long as they are purchased from authorized distributors.

[0044] Example 1

[0045] This embodiment provides a mild disinfecting wipe, which includes a wipe liquid in a mass ratio of 1:0.3 and a spunlace nonwoven fabric made of viscose and polyester.

[0046] The wet wipe liquid consists of the following components by weight: 0.12 parts redox potential regulator, 1.5 parts antimicrobial peptide, 0.1 parts disodium EDTA, 0.09 parts quaternary ammonium bactericide, and 0.02 parts sodium citrate, which are supplemented to 100 parts by deionized water.

[0047] The redox potential regulator is hydrogen peroxide, deacetylated chitosan, and polyvinylpyrrolidone in a mass ratio of 20:1:5.

[0048] The quaternary ammonium salt bactericide is benzalkonium chloride;

[0049] The preparation method of the mild disinfectant wipes is as follows:

[0050] (1) Add deionized water, chelating agent and antimicrobial peptide to the mixing tank in sequence, and stir at 40 rpm for 8 min;

[0051] (2) Add quaternary ammonium salt bactericide to the mixing tank and stir at 30 rpm for 4 min;

[0052] (3) Add pH adjuster and redox potential adjuster to the mixing tank and stir at 50 rpm for 8 min to obtain wet wipe liquid;

[0053] (4) Wet wipe liquid is applied to the spunlace nonwoven fabric through wet wipe production equipment, so that the wet wipe liquid is absorbed by the spunlace nonwoven fabric and adheres to it. After packaging, it is obtained.

[0054] Example 2

[0055] This embodiment provides a mild disinfecting wipe, which comprises a wipe liquid and a spunlace nonwoven fabric in a mass ratio of 1:0.4;

[0056] The wet wipe liquid consists of the following components by weight: 0.1 parts redox potential regulator, 1 part antimicrobial peptide, 0.08 parts disodium EDTA, 0.08 parts quaternary ammonium bactericide, and 0.02 parts sodium citrate, which are supplemented to 100 parts by deionized water.

[0057] The redox potential regulator is hydrogen peroxide, deacetylated chitosan, and polyvinylpyrrolidone in a mass ratio of 10:1:5.

[0058] The quaternary ammonium salt bactericide is benzalkonium chloride;

[0059] The preparation method of the mild disinfectant wipes is as described in Example 1.

[0060] Example 3

[0061] This embodiment provides a mild disinfecting wipe, which comprises a wipe liquid and a spunlace nonwoven fabric in a mass ratio of 1:0.25;

[0062] The wet wipe liquid consists of the following components by weight: 0.12 parts redox potential regulator, 2 parts antimicrobial peptide, 0.1 parts tetrasodium EDTA, 0.1 parts quaternary ammonium bactericide, and 0.03 parts citric acid, which are supplemented to 100 parts by deionized water.

[0063] The redox potential regulator is hydrogen peroxide, deacetylated chitosan, and polyvinylpyrrolidone in a mass ratio of 25:1:5.

[0064] The quaternary ammonium salt bactericide is benzalkonium chloride;

[0065] The preparation method of the mild disinfectant wipes is as described in Example 1.

[0066] Example 4

[0067] This embodiment provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and the one in Embodiment 1 is that the wipe liquid does not contain quaternary ammonium salt bactericide. The reduction is made up by water. The remaining components and dosages are the same as in Embodiment 1. The preparation method is the same as in Embodiment 1.

[0068] Example 5

[0069] This embodiment provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the quaternary ammonium salt bactericide in the wipe liquid is benzalkonium chloride and dialcyldimethylammonium chloride in a mass ratio of 1:1, and the amount of quaternary ammonium salt bactericide remains unchanged. The remaining components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0070] Example 6

[0071] This embodiment provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and the one in Example 1 is that the quaternary ammonium salt bactericide in the wipe liquid is dialcdecyl dimethyl ammonium chloride, and the amount of quaternary ammonium salt bactericide remains unchanged. The other components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0072] Example 7

[0073] This embodiment provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the redox potential regulator in the wipe liquid is hydrogen peroxide and deacetylated chitosan in a mass ratio of 20:1, and the amount of redox potential regulator remains unchanged. The other components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0074] Example 8

[0075] This embodiment provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the redox potential regulator in the wipe liquid is hydrogen peroxide and polyvinylpyrrolidone in a mass ratio of 4:1, and the amount of redox potential regulator remains unchanged. The remaining components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0076] Example 9

[0077] This embodiment provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the redox potential regulator in the wipe liquid is deacetylated chitosan and polyvinylpyrrolidone in a mass ratio of 1:5, and the amount of redox potential regulator remains unchanged. The other components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0078] Example 10

[0079] This embodiment provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the amount of redox potential regulator in the wipe liquid is 0.05 parts, and the composition of the redox potential regulator remains unchanged. The other components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0080] Example 11

[0081] This embodiment provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the amount of redox potential regulator in the wipe liquid is 0.5 parts, and the composition of the redox potential regulator remains unchanged. The other components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0082] Comparative Example 1

[0083] This comparative example provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the wipe liquid does not include antimicrobial peptides. The reduction is made up by an oxidation-reduction potential regulator. The remaining components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0084] Comparative Example 2

[0085] This comparative example provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the wipe liquid does not include an oxidation-reduction potential regulator. The reduction is made up by antimicrobial peptides. The remaining components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0086] Comparative Example 3

[0087] This comparative example provides a mild disinfecting wipe. The only difference between the mild disinfecting wipe and Example 1 is that the wipe liquid does not include an oxidation-reduction potential regulator and antimicrobial peptides. The reduction is made up by water. The remaining components and amounts are the same as in Example 1, and the preparation method is the same as in Example 1.

[0088] Test Example 1: Sterilization Performance Test

[0089] Test subjects: mild disinfecting wipes prepared in Examples 1-11 and Comparative Examples 1-3.

[0090] Test method: The bactericidal ability of the disinfectant wipes was tested according to Appendix E of GB 15979-2024 "Hygienic Requirements for Disposable Sanitary Products". The bactericidal rates of Escherichia coli ATCC25922 and Staphylococcus aureus ATCC6538 are shown in Table 1 (all with an action time of 1 minute).

[0091] Table 1

[0092]

[0093] The data in Table 1 show that the wet wipes prepared in Examples 1-3 of this invention have excellent bactericidal effects, with bactericidal rates of >99.9% against both Escherichia coli and Staphylococcus aureus. Table 1 also indicates that the antimicrobial peptides and the redox potential modifiers work synergistically to enhance bactericidal efficacy. Furthermore, the redox potential modifiers, including hydrogen peroxide, deacetylated chitosan, and polyvinylpyrrolidone, exhibit synergistic effects; the simultaneous presence of all three enhances the product's bactericidal effect.

[0094] Test Example 2: Stimulation Test

[0095] The specific method was as follows: Forty volunteers aged 18-35 years (half male and half female) with no history of allergies were selected. Each subject used the wet wipes prepared in Examples 1-11. After cleaning the subject's arm, the wet wipes were applied to the selected location on the arm using non-irritating adhesive tape. After application, the wipes were gently pressed with fingers to ensure even application to the skin, and left on for 48 hours. During these 48 hours, the subjects kept the patch area dry and avoided strenuous exercise, scratching, and prolonged sun exposure. After 48 hours, the patch was removed and marked. After 30 minutes, once the indentation disappeared, the patch was evaluated under sufficient light.

[0096] The grading criteria for adverse skin reactions are shown in Table 2:

[0097] Table 2

[0098]

[0099] The results are shown in Table 3:

[0100] Table 3

[0101]

[0102] As shown in Table 3, all subjects in Examples 1-3 had negative reactions, indicating that the wipes described in this invention have no adverse effects on the human body, are mild and non-irritating, and have high safety. However, in Examples 5-6, when the quaternary ammonium salt bactericide was not the type selected in this invention, the product had higher irritation.

[0103] The applicant declares that the present invention illustrates a mild disinfectant wipe, its preparation method, and its application through the above embodiments. However, the present invention is not limited to the above embodiments, that is, it does not mean that the present invention must rely on the above embodiments to be implemented. Those skilled in the art should understand that any improvements to the present invention, equivalent substitutions of the raw materials of the product, addition of auxiliary components, and selection of specific methods, etc., all fall within the protection scope and disclosure scope of the present invention.

[0104] The preferred embodiments of the present invention have been described in detail above. However, the present invention is not limited to the specific details in the above embodiments. Within the scope of the technical concept of the present invention, various simple modifications can be made to the technical solution of the present invention, and these simple modifications all fall within the protection scope of the present invention.

[0105] It should also be noted that the various specific technical features described in the above specific embodiments can be combined in any suitable manner without contradiction. In order to avoid unnecessary repetition, the present invention will not describe the various possible combinations separately.

Claims

1. A mild disinfecting wipe, characterized in that, The disinfectant wipes include a wipe liquid and a carrier; The components of the wet wipe liquid include an oxidation-reduction potential modifier, antimicrobial peptides, chelating agents, and deionized water; The redox potential modifier includes any one or a combination of at least two of hydrogen peroxide, deacetylated chitosan, or polyvinylpyrrolidone.

2. The mild disinfecting wipes as described in claim 1, characterized in that, The mass ratio of the carrier to the wet wipe liquid is 1:(2.5-4). Preferably, the carrier includes any one of nonwoven fabric, woven fabric, or cleanroom paper.

3. The mild disinfecting wipes as described in claim 1 or 2, characterized in that, The wet wipe liquid comprises, by weight, 0.01-1 parts of an oxidation-reduction potential regulator, 0.5-2 parts of an antimicrobial peptide, 0.01-0.5 parts of a chelating agent, and 90-99 parts of deionized water; Preferably, the mass ratio of the redox potential regulator to the antimicrobial peptide is 1:(10-20).

4. The mild disinfecting wipes as described in any one of claims 1-3, characterized in that, The redox potential regulator is hydrogen peroxide, deacetylated chitosan and polyvinylpyrrolidone; preferably, the mass ratio of hydrogen peroxide, deacetylated chitosan and polyvinylpyrrolidone is (20-40):(0.1-2):(1-10).

5. The mild disinfecting wipes as described in any one of claims 1-4, characterized in that, The antimicrobial peptide is derived from lactic acid bacteria fermentation products; Preferably, the chelating agent includes any one or a combination of at least two of tetrasodium EDTA, disodium EDTA, or tetrasodium glutamate diacetate.

6. The mild disinfecting wipes as described in any one of claims 1-5, characterized in that, The wet wipe liquid also includes quaternary ammonium salt bactericides and / or pH adjusters. Preferably, the wet wipe liquid further comprises 0.01-1 parts by weight of quaternary ammonium salt bactericide and 0.01-1 parts by weight of pH adjuster.

7. The mild disinfecting wipes as described in any one of claims 1-6, characterized in that, The pH adjuster includes citric acid and / or sodium citrate; Preferably, the quaternary ammonium salt bactericide includes any one or a combination of two of benzalkonium chloride, cetylpyridinium chloride, benzyl chloride, or dialcyldimethylammonium chloride; Preferably, the quaternary ammonium salt bactericide is benzalkonium chloride.

8. A method for preparing a mild disinfecting wipe as described in any one of claims 1-7, characterized in that, The preparation method includes: (1) A mixture was obtained by mixing deionized water, chelating agent and antimicrobial peptide; (2) Add a redox potential regulator to the mixture and mix to obtain a wet wipe solution; (3) The carrier is soaked in wet wipe liquid and packaged to obtain the mild disinfectant wipes.

9. The preparation method according to claim 8, characterized in that, The mixing in step (1) is carried out by stirring, with a stirring speed of 30-50 rpm and a time of 5-10 min; Preferably, the mixing in step (2) is carried out by stirring, the stirring speed is 30-50 rpm, and the time is 8-15 min; Preferably, step (2) further includes adding a quaternary ammonium salt bactericide and / or a pH adjuster.

10. The use of a mild disinfecting wipe as described in any one of claims 1-7 in the preparation of daily necessities.

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