Nerve regulation and control method and system based on 40Hz rhythm stimulation and cognitive training

Abstract

The invention discloses a nerve regulation and control method and system based on 40Hz rhythm stimulation and cognitive training, and the method comprises the steps: selecting training resources suitable for a target user in response to a nerve regulation and control instruction triggered by the target user; wherein the training resources comprise image contents, audio contents and cognitive training tasks; respectively performing 40Hz gamma rhythm modulation on the image content, the audio content and the cognitive training task to obtain cognitive training content with gamma rhythm modulation; and performing cognitive training on the target user based on the cognitive training content so as to perform neural regulation on different brain regions of the target user. Therefore, by adopting the embodiment of the invention, meaningful images, sounds and cognitive training contents are combined, the meaningful contents are more easily accepted by the elderly, the discomfort is reduced, and the training compliance is improved. Multiple types of data are modulated through the 40Hz rhythm, the method can act on a wider brain area, multiple cognitive domains can be activated at the same time, and the neural modulation effect is improved.

Description

Technical Field

[0001] This application relates to the field of neuromodulation technology, and in particular to a neuromodulation method and system based on 40Hz rhythmic stimulation and cognitive training. Background Technology

[0002] Against the backdrop of an increasingly aging society, cognitive decline and Alzheimer's disease have become significant issues affecting the quality of life for the elderly. To improve cognitive function, slow cognitive decline, and enhance their quality of life, non-pharmacological interventions are gaining increasing attention. For example, cognitive training for the elderly using specific neuromodulation techniques in nursing homes, community service centers, and home-based care settings has become an important intervention method.

[0003] Among related technologies, 40Hz gamma oscillations are considered an effective neuromodulation technique capable of improving cognitive brain function. Traditional 40Hz gamma oscillation stimulation methods mainly include 40Hz light flickering and pure tone stimulation. These methods continuously stimulate the brain with light or sound of specific frequencies to achieve neuromodulation.

[0004] However, meaningless light flashes and pure tone stimulation are less acceptable to older adults, easily causing discomfort and leading to poor training compliance. Secondly, a single stimulation method has a limited scope of effect and cannot comprehensively modulate multiple cognitive domains, thus reducing the effectiveness of neural modulation. Summary of the Invention

[0005] This application provides a neuromodulation method and system based on 40Hz rhythmic stimulation and cognitive training. To provide a basic understanding of some aspects of the disclosed embodiments, a brief summary is given below. This summary is not intended as a general commentary, nor is it intended to identify key / important components or describe the scope of protection of these embodiments. Its sole purpose is to present some concepts in a simple form as a prelude to the detailed description that follows.

[0006] In a first aspect, embodiments of this application provide a neural modulation method based on 40Hz rhythmic stimulation and cognitive training, the method comprising: In response to neural modulation commands triggered by the target user, training resources suitable for the target user are selected; the training resources include image content, audio content, and cognitive training tasks. The image content, audio content, and cognitive training task were modulated with 40Hz gamma rhythm to obtain cognitive training content with gamma rhythm modulation. Based on the cognitive training content, cognitive training is performed on the target users to conduct neural modulation on different brain regions of the target users.

[0007] Optionally, the image content, audio content, and cognitive training task are modulated with a 40Hz gamma rhythm to obtain cognitive training content with gamma rhythm modulation, including: Applications developed using Unity3D technology or Vue can perform 40Hz periodic brightness modulation on image content to obtain an image with gamma rhythm modulation. Amplitude modulation technology is used to modulate the audio content at 40Hz to obtain audio with gamma rhythm modulation; Create a preset shape within the screen's field of view. The center of the preset shape is an opaque area, while the perimeter of the preset shape is a completely transparent area. The cognitive training task was set in an opaque area, and a purely transparent area was set to display a brightness that changed periodically at 40 Hz, resulting in a cognitive training task with gamma rhythm modulation. Images with gamma rhythm modulation, audio with gamma rhythm modulation, and cognitive training tasks with gamma rhythm modulation are used as cognitive training content with gamma rhythm modulation.

[0008] Optionally, the image content is subjected to 40Hz periodic brightness modulation to obtain an image with gamma rhythm modulation, including: The current refresh rate of the display system is being monitored. When the current refresh rate is 80Hz, the image content is set to be the first content in an alternating arrangement of one frame of the original image and one frame of white or black pure screen, modulated at 40Hz based on the difference frequency; or, When the current refresh rate is 120Hz, the image content is set to the second content, which is arranged by alternating between two original images and one white or black pure screen, and modulated at 40Hz based on the difference frequency. By setting the amplitude and timing of the periodic changes of the first or second content using a preset software timer, an image with gamma rhythm modulation is obtained.

[0009] Optionally, the audio content is amplitude modulated at 40Hz to obtain audio with gamma rhythm modulation, including: Launch the default audio processing software; the default audio processing software is one of Adobe After Effects, AbletonLive, or Pro Tools. Configure the preset audio processing software parameters, including a modulation frequency of 40Hz and a modulation index; Input the audio content into the preset audio processing software with configured software parameters; Outputs audio with gamma rhythm modulation.

[0010] Optionally, the audio content can be input into preset audio processing software configured with software parameters, including: The mathematical expression for amplitude modulation is invoked by a preset audio processing software with configured software parameters. Obtain the raw audio signal of the audio content; Substituting the original audio signal, the 40Hz modulation frequency, and the modulation index into the mathematical expression, the final audio signal of the audio content is calculated, resulting in audio with gamma rhythm modulation.

[0011] Optional, the mathematical expression is:

[0012] in, It is the original audio signal. It is a modulation frequency of 40Hz. It is the modulation index used to control the depth of modulation. It is the final audio signal of the audio content.

[0013] Optionally, cognitive training content includes images with gamma rhythm modulation, audio with gamma rhythm modulation, and cognitive training tasks with gamma rhythm modulation. Based on the cognitive training content, cognitive training is performed on the target users, including: Obtain the age of the target users; Determine the target user's viewing time based on their age; Based on viewing time, images with gamma rhythm modulation and cognitive training tasks with gamma rhythm modulation are played for the target users. Cognitive training is conducted on target users based on audio with gamma rhythm modulation.

[0014] Optionally, cognitive training is performed on target users based on audio with gamma rhythm modulation, including: Intersperse audio with gamma rhythm modulation into the daily lives of the target users; By combining audio with gamma rhythm modulation with the audio of each movement in a preset exercise program, an exercise program with gamma rhythm modulation is obtained. The program uses exercise programs with gamma rhythm modulation to guide target users in their workouts.

[0015] Optionally, based on audio with gamma rhythm modulation, during cognitive training for the target user, the target user can control a preset 40Hz gamma modulation switch.

[0016] Secondly, embodiments of this application provide a neuromodulation system based on 40Hz rhythmic stimulation and cognitive training, the system comprising: The training resource selection module is used to select training resources suitable for the target user in response to the neural modulation command triggered by the target user; the training resources include image content, audio content, and cognitive training tasks. The 40Hz gamma rhythm modulation module is used to apply 40Hz gamma rhythm modulation to image content, audio content, and cognitive training tasks respectively, to obtain cognitive training content with gamma rhythm modulation. The neuromodulation module is used to perform cognitive training on target users based on cognitive training content, so as to perform neuromodulation on different brain regions of the target users.

[0017] The technical solutions provided in this application embodiment may include the following beneficial effects: In this embodiment, on the one hand, meaningful images, sounds, and cognitive training content are combined. Meaningful content is more easily accepted by older adults, reducing discomfort and thus improving training compliance. On the other hand, by modulating multiple types of data with a 40Hz rhythm, it can act on a wider range of brain regions, simultaneously activating multiple cognitive domains, thus broadening the scope of action and improving the effectiveness of neural modulation.

[0018] It should be understood that the above general description and the following detailed description are exemplary and explanatory only, and do not limit this application. Attached Figure Description

[0019] The accompanying drawings, which are incorporated in and form part of this specification, illustrate embodiments consistent with this application and, together with the description, serve to explain the principles of this application.

[0020] Figure 1 This is a flowchart illustrating a neuromodulation method based on 40Hz rhythmic stimulation and cognitive training provided in an embodiment of this application. Figure 2 This is a schematic diagram of a neural modulation process based on 40Hz rhythmic stimulation and cognitive training provided in this application; Figure 3 This is a schematic diagram of the structure of a neural modulation system based on 40Hz rhythmic stimulation and cognitive training provided in this application; Figure 4 This is a schematic diagram of the structure of an electronic device provided in an embodiment of this application. Detailed Implementation

[0021] The following description and accompanying drawings fully illustrate specific embodiments of this application to enable those skilled in the art to practice them.

[0022] It should be understood that the described embodiments are merely some, not all, of the embodiments in this application. All other embodiments obtained by those skilled in the art based on the embodiments in this application without inventive effort are within the scope of protection of this application.

[0023] In the following description, when referring to the accompanying drawings, the same numbers in different drawings denote the same or similar elements unless otherwise indicated. The embodiments described in the following exemplary embodiments do not represent all embodiments consistent with this application. Rather, they are merely examples of systems and methods consistent with some aspects of this application as detailed in the appended claims.

[0024] In the description of this application, it should be understood that the terms "first," "second," etc., are used for descriptive purposes only and should not be construed as indicating or implying relative importance. Those skilled in the art can understand the specific meaning of the above terms in this application based on the specific circumstances. Furthermore, in the description of this application, unless otherwise stated, "multiple" refers to two or more. "And / or" describes the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, or B existing alone. The character " / " generally indicates that the preceding and following related objects are in an "or" relationship.

[0025] This application provides a neuromodulation method and system based on 40Hz rhythmic stimulation and cognitive training to address the problems existing in the aforementioned related technologies. In the embodiments of this application, on the one hand, meaningful images, sounds, and cognitive training content are combined; meaningful content is more easily accepted by the elderly, reducing discomfort and thus improving training compliance. On the other hand, by modulating multiple types of data with a 40Hz rhythm, it can act on a wider range of brain regions, simultaneously activating multiple cognitive domains, thus broadening the scope of action and improving the effect of neuromodulation. Exemplary embodiments are described in detail below.

[0026] The following will be combined with the appendix Figure 1 - Appendix Figure 2 This application provides a detailed description of the neuromodulation method based on 40Hz rhythmic stimulation and cognitive training, as provided in its embodiments. This method can be implemented using a computer program and can run on a neuromodulation system based on the von Neumann architecture and 40Hz rhythmic stimulation and cognitive training. This computer program can be integrated into applications or run as a standalone utility application.

[0027] Please see Figure 1 This is a flowchart illustrating a neuromodulation method based on 40Hz rhythmic stimulation and cognitive training, as provided in an embodiment of this application. Figure 1As shown, the method in this application embodiment may include the following steps: S101, in response to the neural modulation command triggered by the target user, selects training resources suitable for the target user; wherein, the training resources include image content, audio content and cognitive training tasks; The target users refer to those who use the neuromodulation system, which could be elderly individuals requiring cognitive training or neurorehabilitation. For example, an 85-year-old with mild cognitive impairment (MCI) might want to improve their cognitive function through neuromodulation training. Neuromodulation commands are instructions triggered by the user in some way (such as clicking a button, a voice command, etc.) to initiate neuromodulation training. Training resources are various content used for neuromodulation training, including image content, audio content, and cognitive training tasks. Image content is visual content with 40Hz flicker, such as videos and pictures. For example, a video of natural scenery with 40Hz flicker is used for visual stimulation. Audio content is audio content with 40Hz rhythm modulation, such as music, songs, and speech. For example, a classic old song with 40Hz rhythm modulation is used for auditory stimulation. Cognitive training tasks are tasks designed to improve specific cognitive functions (such as attention, memory, language, etc.). For example, a memory game requires users to memorize images or numbers and recall them within a certain time.

[0028] In some embodiments of this application, the user triggers a neural modulation instruction through some means (such as clicking a button, issuing a voice command, etc.). After receiving the instruction triggered by the user, the system selects appropriate training resources based on the specific needs and preferences of the target user. For example, the system selects appropriate image content, audio content, and cognitive training tasks from a database based on the user profile (such as age, cognitive level, preferences, etc.).

[0029] This includes meaningful visual content such as faces, buildings, hands, tools, human actions and movements, images of plants and animals in nature, and textual images. Audio content includes meaningful and pleasant content such as music, songs, speech, and sounds of nature. It also includes sounds and images related to physical movement, such as finger exercises, calisthenics, and audiovisual materials depicting human actions and movements. Cognitive training tasks include, but are not limited to, training in attention, memory, language, executive function, number sense, and audiovisual perception.

[0030] For example, an elderly person opens a neuromodulation training app on their phone and clicks the "Start Training" button. Based on the elderly person's user profile (85 years old, mild cognitive impairment, preference for natural scenery and old songs), the system selects the following training resources from its database: Image content: A video of natural scenery with 40Hz flicker.

[0031] Audio content: A classic old song with a 40Hz rhythm modulation.

[0032] Cognitive training task: A simple memory game that requires the elderly to memorize a series of images and recall them within a certain time.

[0033] S102, respectively apply 40Hz gamma rhythm modulation to the image content, audio content and cognitive training task to obtain cognitive training content with gamma rhythm modulation. Among them, 40Hz gamma rhythm modulation is to stimulate the brain's gamma band (brain waves of about 40Hz) by embedding a periodic change of 40Hz into the image or audio signal.

[0034] In some embodiments of this application, the specific process of applying 40Hz gamma rhythm modulation to image content, audio content, and cognitive training tasks to obtain gamma rhythm-modulated cognitive training content includes: using Unity3D technology or Vue-developed application software to perform 40Hz periodic brightness modulation on image content to obtain an image with gamma rhythm modulation; using amplitude modulation technology to perform 40Hz amplitude modulation on audio content to obtain audio with gamma rhythm modulation; creating a preset shape in the screen's field of view, with the middle part of the preset shape being an opaque area and the periphery of the preset shape being a completely transparent area; setting the cognitive training task in the opaque area and setting the completely transparent area to display a periodically changing brightness of 40Hz to obtain a cognitive training task with gamma rhythm modulation; and using the image with gamma rhythm modulation, the audio with gamma rhythm modulation, and the cognitive training task with gamma rhythm modulation as the cognitive training content with gamma rhythm modulation.

[0035] Specifically, the process of performing 40Hz periodic brightness modulation on image content to obtain an image with gamma rhythm modulation includes: detecting the current refresh rate of the display system; when the current refresh rate is 80Hz, setting the image content to a first content consisting of alternating frames of original image and white or black pure screen, and modulating it at 40Hz based on the difference frequency; or, when the current refresh rate is 120Hz, setting the image content to a second content consisting of alternating frames of original image and white or black pure screen, and modulating it at 40Hz based on the difference frequency; and setting the amplitude and timing of the periodic changes of the first or second content through a preset software timer to obtain an image with gamma rhythm modulation.

[0036] One possible implementation involves selecting a meaningful video or image as the image content. Software tools (such as Unity3D or specialized video editing software) are used to periodically modulate the brightness of the video or image at 40Hz. This generates image content with a 40Hz flicker.

[0037] For example, in Unity3D, a software timer can be used to control the periodic changes in screen brightness, so that the screen brightness completes a full brightness change within a period of approximately 25 milliseconds.

[0038] Specific methods include: developing application software for personal computers or smart tablets / phones, based on development technologies such as Unity3D or Vue, to perform 40Hz periodic brightness modulation on the presented video and still images, achieving a 40Hz visual effect through periodic changes in screen brightness. In the Unity3D rendering pipeline, a software timer controls the amplitude and timing of the periodic changes, ensuring that the screen brightness completes a full brightness change within approximately 25 milliseconds. In Unity3D, in the Update function corresponding to each frame, when the accumulated deltaTime reaches 25 milliseconds, the screen brightness parameters and the 3D spatial position of the AudioSource are adjusted, and the timing restarts.

[0039] Specifically, the process of performing 40Hz amplitude modulation on audio content to obtain audio with gamma rhythm modulation includes: starting the preset audio processing software; the preset audio processing software is one of Adobe After Effects, AbletonLive, or Pro Tools; configuring the software parameters of the preset audio processing software, including the 40Hz modulation frequency and modulation index; inputting the audio content into the preset audio processing software with the configured software parameters; and outputting the audio with gamma rhythm modulation.

[0040] Specifically, the process of inputting audio content into preset audio processing software with configured software parameters includes: calling the mathematical expression of amplitude modulation through the preset audio processing software with configured software parameters; obtaining the original audio signal of the audio content; substituting the original audio signal, the 40Hz modulation frequency, and the modulation index into the mathematical expression to calculate the final audio signal of the audio content, thus obtaining audio with gamma rhythm modulation.

[0041] Specifically, the mathematical expression is:

[0042] in, It is the original audio signal. It is a modulation frequency of 40Hz. It is the modulation index used to control the depth of modulation. It is the final audio signal of the audio content.

[0043] In a possible implementation, an audio editing software (such as Adobe Audition, Ableton Live, etc.) is used to perform amplitude modulation (AM) on the audio at 40 Hz. Audio content with a 40-Hz volume variation is generated. For example, in Adobe Audition, amplitude modulation (AM) technology is used to carry a 40-Hz modulation signal by changing the amplitude of the carrier signal. For example, in Ableton Live, the LFO modulation function of "Auto Filter" or "EQ Eight" is used to map a 40-Hz sine wave to the volume parameter.

[0044] It should be noted that compared with the audio superposition scheme in the prior art, the advantage of the method of this application is that it will not introduce an additional 40-Hz audio signal (that is, it will not add an obvious 40-Hz component to the spectrum), but only change the amplitude of the original signal at a frequency of 40 Hz.

[0045] Specifically, the specific process of performing 40-Hz gamma rhythm modulation on the cognitive training task includes: designing a cognitive training task, such as a memory game. Add a 40-Hz visual cue (such as a flicker at the edge of the screen) to the visual interface of the task. Add a 40-Hz volume variation to the audio cue of the task. Generate a cognitive training task with 40-Hz visual and auditory cues.

[0046] For example, make a mask similar to a "hui" character shape in the screen viewing area, with an opaque area in the middle part and a pure transparent area in the peripheral part. The training task is displayed in the middle part, and a periodically changing brightness of 40 Hz is displayed in the peripheral part. [[ID=]10]

[0047] Among them, the above-mentioned audiovisual content is implemented on the software side, and the front end of the software completely independently implements the 40-Hz visual and auditory mode, and the user can freely turn on and off the 40-Hz mode.

[0048] S103, based on the cognitive training content, perform cognitive training on the target user to perform neural regulation on different brain regions of the target user.

[0049] Among them, the cognitive training content includes images with gamma rhythm modulation, audio with gamma rhythm modulation, and cognitive training tasks with gamma rhythm modulation.

[0050] In some embodiments of this application, the specific process of performing cognitive training on the target user based on the cognitive training content includes: obtaining the age of the target user; determining the viewing duration of the target user based on the age of the target user; playing images with gamma rhythm modulation and cognitive training tasks with gamma rhythm modulation for the target user based on the viewing duration; performing cognitive training on the target user based on the audio with gamma rhythm modulation.

[0051] Specifically, the process of cognitive training for target users based on gamma-rhythm modulated audio includes: playing gamma-rhythm modulated audio in the daily lives of target users; combining the gamma-rhythm modulated audio with the audio of each movement in a preset exercise program to obtain a gamma-rhythm modulated exercise program; and using the gamma-rhythm modulated exercise program to guide the target users in exercising.

[0052] Among them, based on audio with gamma rhythm modulation, during the cognitive training process for target users, the target users are allowed to control the preset 40Hz gamma modulation switch themselves.

[0053] In one possible implementation, 20 minutes of gamma-modulated cognitive training is used daily. For individuals aged 80 and above, it is recommended to use cognitive training content suitable for older adults, which should be simpler, and each session should not exceed 15 minutes. The images and sounds used in the cognitive training are pre-processed with gamma modulation.

[0054] In one possible implementation, viewers would watch videos for 30 minutes at a time, with each session for older adults not exceeding 20 minutes. The audiovisual stimuli would include, but not be limited to, social news (neurostimulation reaching the brain regions responsible for textual and language processing and maintaining a connection with social reality), food preparation (neurostimulation reaching functions such as motor information processing and higher cognitive planning and execution), songs (neurostimulation reaching the brain regions responsible for speech and intonation processing), old movies and songs (neurostimulation reaching the brain regions responsible for long-term memory), sports competitions, and scenic documentaries.

[0055] One possible implementation involves interspersing gamma-modulated audio stimuli, such as background music, songs, and meaningful readings, into the lives of elderly users.

[0056] One possible implementation involves using guided sounds or music with gamma rhythm modulation to guide and lead elderly people in physical exercises such as calisthenics, Baduanjin (Eight Pieces of Brocade), Tai Chi, and finger exercises. This combines neural modulation signals with physical movement exercises.

[0057] For example Figure 2 As shown, Figure 2 This application provides a schematic block diagram of a neural modulation process based on 40Hz rhythmic stimulation and cognitive training. After the user triggers the neural modulation command, the system sequentially selects training resources, modulates the training resources with 40Hz gamma, and finally performs cognitive training on the user based on the modulated content to perform neural modulation on the user.

[0058] In this embodiment, on the one hand, meaningful images, sounds, and cognitive training content are combined. Meaningful content is more easily accepted by older adults, reducing discomfort and thus improving training compliance. On the other hand, by modulating multiple types of data with a 40Hz rhythm, it can act on a wider range of brain regions, simultaneously activating multiple cognitive domains, thus broadening the scope of action and improving the effectiveness of neural modulation.

[0059] It should be noted that this application demonstrates significant effects in improving cognitive function, alleviating neuropsychiatric symptoms, enhancing sleep quality, and relieving caregiver stress, exhibiting good clinical applicability and promotional value. This technology can be widely applied in elderly care institutions, community service centers, and home-based elderly care scenarios, helping to slow cognitive decline, reduce social medical and care costs, improve the quality of life and social participation of the very elderly, and simultaneously bring new development opportunities to the silver economy and the health technology industry.

[0060] The following are system embodiments of this application, which can be used to execute the method embodiments of this application. For details not disclosed in the system embodiments of this application, please refer to the method embodiments of this application.

[0061] Please see Figure 3 This illustration shows a schematic diagram of a neuromodulation system based on 40Hz rhythmic stimulation and cognitive training, provided in an exemplary embodiment of this application. This neuromodulation system based on 40Hz rhythmic stimulation and cognitive training can be implemented as all or part of an electronic device through software, hardware, or a combination of both. System 1 includes a training resource selection module 10, a 40Hz gamma rhythm modulation module 20, and a neuromodulation module 30.

[0062] The training resource selection module 10 is used to select training resources suitable for the target user in response to the neural modulation command triggered by the target user; wherein, the training resources include image content, audio content and cognitive training tasks; The 40Hz gamma rhythm modulation module 20 is used to perform 40Hz gamma rhythm modulation on image content, audio content and cognitive training task respectively to obtain cognitive training content with gamma rhythm modulation. The neuromodulation module 30 is used to perform cognitive training on the target user based on cognitive training content, so as to perform neuromodulation on different brain regions of the target user.

[0063] It should be noted that the above embodiments of the neuromodulation system based on 40Hz rhythmic stimulation and cognitive training, when executing the neuromodulation method based on 40Hz rhythmic stimulation and cognitive training, are only illustrative examples of the above functional module division. In practical applications, the above functions can be assigned to different functional modules as needed, that is, the internal structure of the electronic device can be divided into different functional modules to complete all or part of the functions described above. Furthermore, the neuromodulation system based on 40Hz rhythmic stimulation and cognitive training provided in the above embodiments and the neuromodulation method embodiments based on 40Hz rhythmic stimulation and cognitive training belong to the same concept, and their implementation process is detailed in the method embodiments, which will not be repeated here.

[0064] The sequence numbers of the embodiments in this application are for descriptive purposes only and do not represent the superiority or inferiority of the embodiments.

[0065] In this embodiment, on the one hand, meaningful images, sounds, and cognitive training content are combined. Meaningful content is more easily accepted by older adults, reducing discomfort and thus improving training compliance. On the other hand, by modulating multiple types of data with a 40Hz rhythm, it can act on a wider range of brain regions, simultaneously activating multiple cognitive domains, thus broadening the scope of action and improving the effectiveness of neural modulation.

[0066] This application also provides a computer-readable medium having program instructions stored thereon, which, when executed by a processor, implement the neuromodulation method based on 40Hz rhythmic stimulation and cognitive training provided in the above-described method embodiments.

[0067] This application also provides a computer program product containing instructions that, when run on a computer, cause the computer to execute the neuromodulation method based on 40Hz rhythmic stimulation and cognitive training according to the various method embodiments described above.

[0068] Please see Figure 4 This is a schematic diagram of the structure of an electronic device provided in an embodiment of this application. Figure 4 As shown, the electronic device 1000 may include: at least one processor 1001, at least one network interface 1004, a user interface 1003, a memory 1005, and at least one communication bus 1002.

[0069] The communication bus 1002 is used to realize the connection and communication between these components.

[0070] The user interface 1003 may include a display screen and a camera. Optionally, the user interface 1003 may also include a standard wired interface and a wireless interface.

[0071] The network interface 1004 may optionally include a standard wired interface or a wireless interface (such as a Wi-Fi interface).

[0072] The processor 1001 may include one or more processing cores. The processor 1001 connects to various parts within the electronic device 1000 using various interfaces and lines. It executes various functions and processes data by running or executing instructions, programs, code sets, or instruction sets stored in the memory 1005, and by calling data stored in the memory 1005. Optionally, the processor 1001 may be implemented using at least one hardware form selected from Digital Signal Processing (DSP), Field-Programmable Gate Array (FPGA), and Programmable Logic Array (PLA). The processor 1001 may integrate one or more of the following: a Central Processing Unit (CPU), a Graphics Processing Unit (GPU), and a modem. The CPU primarily handles the operating system, user interface, and applications; the GPU is responsible for rendering and drawing the content to be displayed on the screen; and the modem handles wireless communication. It is understood that the modem may also be implemented as a separate chip, without being integrated into the processor 1001.

[0073] The memory 1005 may include random access memory (RAM) or read-only memory. Optionally, the memory 1005 may include a non-transitory computer-readable storage medium. The memory 1005 can be used to store instructions, programs, code, code sets, or instruction sets. The memory 1005 may include a program storage area and a data storage area, wherein the program storage area may store instructions for implementing an operating system, instructions for at least one function (such as touch function, sound playback function, image playback function, etc.), instructions for implementing the above-described method embodiments, etc.; the data storage area may store data involved in the above-described method embodiments, etc. Optionally, the memory 1005 may also be at least one storage system located remotely from the aforementioned processor 1001. Figure 4As shown, the memory 1005, which serves as a computer storage medium, may include an operating system, a network communication module, a user interface module, and a neuromodulation application based on 40Hz rhythmic stimulation and cognitive training.

[0074] exist Figure 4 In the illustrated electronic device 1000, the user interface 1003 is mainly used to provide an input interface for the user and to acquire user input data; while the processor 1001 can be used to call the neuromodulation application based on 40Hz rhythmic stimulation and cognitive training stored in the memory 1005, and specifically perform the following operations: In response to neural modulation commands triggered by the target user, training resources suitable for the target user are selected; the training resources include image content, audio content, and cognitive training tasks. The image content, audio content, and cognitive training task were modulated with 40Hz gamma rhythm to obtain cognitive training content with gamma rhythm modulation. Based on the cognitive training content, cognitive training is performed on the target users to conduct neural modulation on different brain regions of the target users.

[0075] In one embodiment, when the processor 1001 performs 40Hz gamma rhythm modulation on image content, audio content, and cognitive training tasks respectively to obtain cognitive training content with gamma rhythm modulation, it specifically performs the following operations: Applications developed using Unity3D technology or Vue can perform 40Hz periodic brightness modulation on image content to obtain an image with gamma rhythm modulation. Amplitude modulation technology is used to modulate the audio content at 40Hz to obtain audio with gamma rhythm modulation; Create a preset shape within the screen's field of view. The center of the preset shape is an opaque area, while the perimeter of the preset shape is a completely transparent area. The cognitive training task was set in an opaque area, and a purely transparent area was set to display a brightness that changed periodically at 40 Hz, resulting in a cognitive training task with gamma rhythm modulation. Images with gamma rhythm modulation, audio with gamma rhythm modulation, and cognitive training tasks with gamma rhythm modulation are used as cognitive training content with gamma rhythm modulation.

[0076] In one embodiment, when the processor 1001 performs 40Hz periodic luminance modulation on the image content to obtain an image with gamma rhythm modulation, it specifically performs the following operations: The current refresh rate of the display system is being monitored. When the current refresh rate is 80Hz, the image content is set to be the first content in an alternating arrangement of one frame of the original image and one frame of white or black pure screen, modulated at 40Hz based on the difference frequency; or, When the current refresh rate is 120Hz, the image content is set to the second content, which is arranged by alternating between two original images and one white or black pure screen, and modulated at 40Hz based on the difference frequency. By setting the amplitude and timing of the periodic changes of the first or second content using a preset software timer, an image with gamma rhythm modulation is obtained.

[0077] In one embodiment, when processor 1001 performs 40Hz amplitude modulation on audio content to obtain audio with gamma rhythm modulation, it specifically performs the following operations: Launch the default audio processing software; the default audio processing software is one of Adobe After Effects, AbletonLive, or Pro Tools. Configure the preset audio processing software parameters, including a modulation frequency of 40Hz and a modulation index; Input the audio content into the preset audio processing software with configured software parameters; Outputs audio with gamma rhythm modulation.

[0078] In one embodiment, when the processor 1001 executes preset audio processing software configured with software parameters, it specifically performs the following operations: The mathematical expression for amplitude modulation is invoked by a preset audio processing software with configured software parameters. Obtain the raw audio signal of the audio content; Substituting the original audio signal, the 40Hz modulation frequency, and the modulation index into the mathematical expression, the final audio signal of the audio content is calculated, resulting in audio with gamma rhythm modulation.

[0079] In one embodiment, when the processor 1001 performs cognitive training on a target user based on cognitive training content, it specifically performs the following operations: Obtain the age of the target users; Determine the target user's viewing time based on their age; Based on viewing time, images with gamma rhythm modulation and cognitive training tasks with gamma rhythm modulation are played for the target users. Cognitive training is conducted on target users based on audio with gamma rhythm modulation.

[0080] In one embodiment, when the processor 1001 performs cognitive training on a target user based on audio with gamma rhythm modulation, it specifically performs the following operations: Intersperse audio with gamma rhythm modulation into the daily lives of the target users; By combining audio with gamma rhythm modulation with the audio of each movement in a preset exercise program, an exercise program with gamma rhythm modulation is obtained. The program uses exercise programs with gamma rhythm modulation to guide target users in their workouts.

[0081] In this embodiment, on the one hand, meaningful images, sounds, and cognitive training content are combined. Meaningful content is more easily accepted by older adults, reducing discomfort and thus improving training compliance. On the other hand, by modulating multiple types of data with a 40Hz rhythm, it can act on a wider range of brain regions, simultaneously activating multiple cognitive domains, thus broadening the scope of action and improving the effectiveness of neural modulation.

[0082] Those skilled in the art will understand that all or part of the processes in the above embodiments can be implemented by a computer program instructing related hardware. The neuromodulation program based on 40Hz rhythmic stimulation and cognitive training can be stored in a computer-readable storage medium. When executed, the program can include the processes of the embodiments of the above methods. The storage medium for the neuromodulation program based on 40Hz rhythmic stimulation and cognitive training can be a magnetic disk, optical disk, read-only memory, or random access memory, etc.

[0083] The above-disclosed embodiments are merely preferred embodiments of this application and should not be construed as limiting the scope of this application. Therefore, any equivalent variations made in accordance with the claims of this application shall still fall within the scope of this application.

Claims

1. A neural modulation method based on 40Hz rhythmic stimulation and cognitive training, characterized in that, The method includes: In response to a neural modulation command triggered by a target user, training resources suitable for the target user are selected; wherein, the training resources include image content, audio content, and cognitive training tasks; The image content, audio content, and cognitive training task are respectively subjected to 40Hz gamma rhythm modulation to obtain cognitive training content with gamma rhythm modulation. Based on the cognitive training content, cognitive training is performed on the target user to perform neural modulation on different brain regions of the target user.

2. The method according to claim 1, characterized in that, The step of applying 40Hz gamma rhythm modulation to the image content, audio content, and cognitive training task respectively to obtain cognitive training content with gamma rhythm modulation includes: Using Unity3D technology or Vue-developed application software, the image content is subjected to 40Hz periodic brightness modulation to obtain an image with gamma rhythm modulation. Amplitude modulation technology is used to modulate the audio content at 40Hz to obtain audio with gamma rhythm modulation; Create a preset shape in the screen's field of view area, wherein the middle part of the preset shape is an opaque area and the periphery of the preset shape is a completely transparent area; The cognitive training task is set in the opaque area, and the pure transparent area is set to display a brightness that changes periodically at 40 Hz, thus obtaining a cognitive training task with gamma rhythm modulation. Images with gamma rhythm modulation, audio with gamma rhythm modulation, and cognitive training tasks with gamma rhythm modulation are used as cognitive training content with gamma rhythm modulation.

3. The method according to claim 2, characterized in that, The step of performing periodic brightness modulation of the image content at 40 Hz to obtain an image with gamma rhythm modulation includes: The current refresh rate of the display system is being monitored. When the current refresh rate is 80Hz, the image content is set to a first content formatted with alternating frames of original image and white or black pure screen, modulated at 40Hz based on the difference frequency; or... When the current refresh rate is 120Hz, the image content is set as a second content that alternates between two original images and one white or black pure screen, and modulated at 40Hz based on the difference frequency. An image with gamma rhythm modulation is obtained by setting the amplitude and timing of the periodic changes of the first or second content using a preset software timer.

4. The method according to claim 2, characterized in that, The step of performing 40Hz amplitude modulation on the audio content to obtain audio with gamma rhythm modulation includes: Launch the default audio processing software; the default audio processing software is one of Adobe After Effects, Ableton Live, or Pro Tools. Configure the software parameters of the preset audio processing software, including a modulation frequency of 40Hz and a modulation index; The audio content is input into a preset audio processing software configured with software parameters; Outputs audio with gamma rhythm modulation.

5. The method according to claim 4, characterized in that, The step of inputting the audio content into a preset audio processing software configured with software parameters includes: The mathematical expression for amplitude modulation is invoked by a preset audio processing software with configured software parameters. Obtain the original audio signal of the audio content; Substituting the original audio signal, the 40Hz modulation frequency, and the modulation index into the mathematical expression, the final audio signal of the audio content is calculated, resulting in audio with gamma rhythm modulation.

6. The method according to claim 5, characterized in that, The mathematical expression is: in, It is the original audio signal. It is a modulation frequency of 40Hz. It is the modulation index used to control the depth of modulation. It is the final audio signal of the audio content.

7. The method according to claim 1, characterized in that, The cognitive training content includes images with gamma rhythm modulation, audio with gamma rhythm modulation, and cognitive training tasks with gamma rhythm modulation. The step of performing cognitive training on the target user based on the cognitive training content includes: Obtain the age of the target user; Based on the age of the target user, determine the viewing duration of the target user; Based on the viewing duration, the gamma-rhythm modulated image and the gamma-rhythm modulated cognitive training task are played for the target user. Cognitive training is performed on the target user based on the audio with gamma rhythm modulation.

8. The method according to claim 7, characterized in that, The cognitive training for the target user based on the audio with gamma rhythm modulation includes: The audio with gamma rhythm modulation is interspersed throughout the daily life of the target user; The audio with gamma rhythm modulation is combined with the audio of each movement in the preset exercise program to obtain the exercise program with gamma rhythm modulation. The target user is guided to exercise using a workout program with gamma rhythm modulation.

9. The method according to claim 7, characterized in that, During the cognitive training process for the target user based on the audio with gamma rhythm modulation, the target user is allowed to control a preset 40Hz gamma modulation switch.

10. A neural modulation system based on 40Hz rhythmic stimulation and cognitive training, characterized in that, The system includes: The training resource selection module is used to select training resources suitable for the target user in response to a neural modulation command triggered by the target user; wherein, the training resources include image content, audio content, and cognitive training tasks; A 40Hz gamma rhythm modulation module is used to perform 40Hz gamma rhythm modulation on the image content, audio content, and cognitive training task respectively to obtain cognitive training content with gamma rhythm modulation. The neural modulation module is used to perform cognitive training on the target user based on the cognitive training content, so as to perform neural modulation on different brain regions of the target user.

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