Low-temperature treatment system

Abstract

The embodiment of the invention relates to a low-temperature treatment system, and the system comprises a treatment cap which comprises a protection layer, a cooling layer and a skin-attaching layer, the temperature control module is arranged between the cooling layer and the skin attaching layer; the heat exchange unit is arranged between the skin attaching layer and the temperature control module and is in contact with the temperature control module; the ice cap temperature sensor is arranged on the side, close to the cooling layer, of the skin attaching layer; a body surface temperature sensor; an anus temperature sensor; the display screen is configured to receive a target temperature control type and a target treatment type; and the controller is electrically connected with the temperature control module, the ice cap temperature sensor, the body surface temperature sensor, the anus temperature sensor and the display screen, and is configured to determine a target temperature control mode based on the target temperature control type and the target treatment type, and control the temperature control module based on the target temperature control mode. According to the low-temperature treatment system, the corresponding temperature control mode can be obtained according to the treatment type and the temperature control type of the patient, so that the temperature control module is adaptively controlled, and the accuracy of low-temperature treatment is ensured.

Description

Technical Field

[0001] This application relates to the field of medical device technology, and in particular to a cryotherapy system. Background Technology

[0002] Hypothermia therapy, as an important clinical approach, has made significant progress in reducing intracranial pressure and protecting neurology. Studies have shown that controlling the patient's core temperature to the sub-hypothermic range (32-36℃) can effectively reduce secondary damage after brain injury. Ice caps are mainly used for head cooling, which can effectively lower intracranial temperature, reduce brain cell metabolism and oxygen demand, improve brain cell tolerance to hypoxia, and prevent cerebral edema.

[0003] Hypothermia treatment requires prolonged maintenance, typically lasting at least 24 to 72 hours, and the rewarming process must be slow to prevent intracranial pressure rebound and other complications. Excessive rewarming can lead to systemic vasodilation, hypotension, reduced cerebral blood flow, and impaired brain function. The duration of hypothermia and the rate of rewarming can vary greatly among patients, and inappropriate hypothermia treatment or rewarming can cause secondary harm to the patient. Summary of the Invention

[0004] One objective of this application is to provide a cryotherapy system that can obtain a corresponding temperature control mode according to the treatment type and temperature control type of different patients, so as to adaptively control the temperature control module, ensure the accuracy of cryotherapy, and protect patients to the greatest extent possible.

[0005] In a first aspect, embodiments of this application provide a cryotherapy system, comprising:

[0006] The treatment cap includes a layered protective layer, a cooling layer, and a skin-adhesive layer;

[0007] A temperature control module is disposed between the cooling layer and the skin-contact layer and is configured to absorb or release heat.

[0008] A heat exchange unit is disposed between the skin-contact layer and the temperature control module and is in contact with the temperature control module. It is configured to reduce or increase the temperature inside the treatment cap based on the heat transfer between the temperature control module and the heat exchange unit.

[0009] An ice cap temperature sensor is disposed on the side of the skin-contact layer near the cooling layer and is configured to detect the liquid temperature of the coolant transferred by the heat exchange unit;

[0010] A body surface temperature sensor is configured to detect the user's body surface temperature;

[0011] An anal temperature sensor is configured to detect the user's anal temperature;

[0012] The display screen is configured to receive the target temperature control type and the target treatment type.

[0013] The controller, which is electrically connected to the temperature control module, the ice cap temperature sensor, the body surface temperature sensor, the anal temperature sensor, and the display screen, is configured to: determine a target temperature control mode based on the target temperature control type and the target treatment type, and control the temperature control module based on the target temperature control mode.

[0014] In some embodiments, the temperature control type includes cooling type and reheating type, the temperature control mode includes cooling mode and reheating mode, and the controller is configured to:

[0015] In response to the target temperature control type being a cooling type, the cooling mode matching the target treatment type is determined from a set of preset cooling modes as the target temperature control mode; or,

[0016] In response to the target temperature control type being a rewarming type, the rewarming mode that matches the target treatment type is determined as the target temperature control mode from among a plurality of preset rewarming modes.

[0017] In some embodiments, the controller is configured to:

[0018] Determine the temperature control information corresponding to the target temperature control mode, wherein the temperature control information includes the target temperature;

[0019] Based on the Kalman filter algorithm, the multiple body surface temperatures and multiple anal temperatures are filtered to obtain the target body surface temperature and the target anal temperature.

[0020] A temperature matching the target treatment type is determined between the target body surface temperature and the target anal temperature as the target monitoring temperature;

[0021] The temperature control module is controlled based on the target temperature and the target monitored temperature.

[0022] In some embodiments, the temperature control information further includes a temperature maintenance time, and the controller is configured to:

[0023] Determine whether the target monitored temperature is equal to the target temperature;

[0024] If the temperature is equal to the target temperature, then the temperature control module will maintain the temperature inside the treatment cap at the target temperature according to the temperature maintenance time.

[0025] If the temperature is not equal to the target temperature, the temperature control module is controlled to adjust the temperature inside the treatment cap so that the temperature inside the treatment cap is equal to the target temperature.

[0026] In some embodiments, the temperature control information further includes time limit information for the temperature inside the treatment cap to reach the target temperature, and the controller is configured to:

[0027] Determine a reference monitoring temperature before the user wears the treatment cap, wherein the reference monitoring temperature matches the target treatment type;

[0028] The absolute value of the difference between the reference monitoring temperature and the target temperature is calculated to obtain the temperature difference;

[0029] The target temperature control rate is calculated based on the temperature difference and the time limit information;

[0030] Based on the target temperature control rate, the temperature control module adjusts the temperature inside the treatment cap so that the temperature inside the treatment cap equals the target temperature.

[0031] In some embodiments, the temperature control module is a Peltier module, and the controller is configured to:

[0032] Calculate the target drive current based on the target temperature control rate;

[0033] The target driving current is controlled to be transmitted to the Peltier module in the direction of the target current corresponding to the target temperature control type, so that the temperature inside the treatment cap is equal to the target temperature.

[0034] In some embodiments, the controller is configured to:

[0035] In response to the target temperature control type being cooling type, the first current direction is determined as the target current direction;

[0036] In response to the target temperature control type being a rewarming type, the second current direction is determined as the target current direction, which is opposite to the first current direction.

[0037] In some embodiments, the controller is configured to:

[0038] Obtain a current library that matches the target treatment type, wherein the current library includes multiple temperature control rates and a current corresponding to each temperature control rate;

[0039] The current corresponding to the target temperature control rate is found in the current library and used as the target drive current.

[0040] In some embodiments, the controller is configured to:

[0041] The target rate range is determined based on the current pool, and the target rate range is jointly defined by the first temperature control rate and the second temperature control rate, wherein the target temperature control rate is within the target rate range.

[0042] The current corresponding to the first temperature control rate is determined as the first current, and the current corresponding to the second temperature control rate is determined as the second current;

[0043] A target linear function is generated based on a linear interpolation algorithm, the first temperature control rate, the second temperature control rate, the first current, and the second current. The target linear function is a function with the temperature control rate as the independent variable and the current as the dependent variable.

[0044] The target driving current is calculated based on the target linear function and the target temperature control rate.

[0045] In some embodiments, it also includes:

[0046] An intracranial pressure sensor is electrically connected to the controller; and / or,

[0047] An electroencephalogram (EEG) sensor is electrically connected to the controller; and / or,

[0048] The wireless communication module is electrically connected to the controller.

[0049] Unlike existing technologies, the cryotherapy system provided in this application includes: a treatment cap, comprising a protective layer, a cooling layer, and a skin-adhering layer stacked together; a temperature control module disposed between the cooling layer and the skin-adhering layer, configured to absorb or release heat; a heat exchange unit disposed between the skin-adhering layer and the temperature control module and in contact with the temperature control module, configured to lower or raise the internal temperature of the treatment cap based on heat transfer between the temperature control module and the heat exchange unit; an ice cap temperature sensor disposed on the side of the skin-adhering layer near the cooling layer, configured to detect the liquid temperature of the coolant transferred by the heat exchange unit; a body surface temperature sensor configured to detect the user's body surface temperature; an anal temperature sensor configured to detect the user's anal temperature; a display screen configured to receive a target temperature control type and a target treatment type; and a controller electrically connected to the temperature control module, the ice cap temperature sensor, the body surface temperature sensor, the anal temperature sensor, and the display screen, configured to: determine a target temperature control mode based on the target temperature control type and the target treatment type, and control the temperature control module based on the target temperature control mode.

[0050] The cryotherapy system provided in this application acquires temperature data through an ice cap temperature sensor, a body surface temperature sensor, and a rectal temperature sensor. Based on the temperature data, the patient's target temperature control type, and the target treatment type, a target temperature control mode is determined to control the temperature control module. This ensures the accuracy of cryotherapy, meets the user's need for continuous monitoring and intelligent adjustment of the treatment cap temperature, and protects the patient to the greatest extent possible. Attached Figure Description

[0051] To more clearly illustrate the technical solutions of the embodiments of this application, the drawings used in the description of the embodiments of this application will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort.

[0052] Figure 1 This is a schematic diagram of the structure of a cryotherapy system provided in some embodiments of this application;

[0053] Figure 2 Schematic diagrams of the structure of a cryotherapy system provided in other embodiments of this application;

[0054] Figure 3 A schematic flowchart illustrating the control method of a cryotherapy system provided in some embodiments of this application;

[0055] Figure 4 This application provides schematic diagrams of the control device for a cryotherapy system according to some embodiments.

[0056] Figure 5 This is a schematic diagram of the controller in a cryotherapy system provided in some embodiments of this application.

[0057] Explanation of reference numerals in the attached figures:

[0058] 100-Cryotherapy System;

[0059] 10-Therapeutic cap, 11-Protective layer, 12-Cooling layer, 13-Skin-adhesive layer;

[0060] 20-Temperature control module, 30-Heat exchange unit, 40-Ice cap temperature sensor, 50-Body surface temperature sensor, 60-Anal temperature sensor, 70-Display screen, 80-Controller, 90-Intracranial pressure sensor, 91-EEG sensor, 92-Wireless communication module. Detailed Implementation

[0061] To make the objectives, technical solutions, and advantages of this application clearer, the following detailed description is provided in conjunction with the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative and not intended to limit the scope of this application. All other embodiments obtained by those skilled in the art based on the embodiments in this application without inventive effort are within the scope of protection of this application.

[0062] It should be noted that, unless there is a conflict, the various features in the embodiments of this application can be combined with each other, all of which are within the protection scope of this application. Furthermore, although functional modules are divided in the device schematic diagram and a logical order is shown in the flowchart, in some cases, the steps shown or described can be executed in a different order than the module division in the device or the order in the flowchart. Moreover, the terms "first," "second," and "third" used in this application do not limit the data or execution order, but only distinguish identical or similar items with essentially the same function and effect.

[0063] Hypothermia therapy, as an important clinical approach, has made significant progress in reducing intracranial pressure and protecting neurology. Studies have shown that controlling the patient's core temperature to the sub-hypothermic range (32-36℃) can effectively reduce secondary damage after brain injury. Ice caps are mainly used for head cooling, which can effectively lower intracranial temperature, reduce brain cell metabolism and oxygen demand, improve brain cell tolerance to hypoxia, and prevent cerebral edema.

[0064] Hypothermia therapy has side effects such as cardiac arrhythmia, severe hypokalemia, coagulation disorders, pulmonary infection, chills, gastrointestinal dysfunction, and an increased risk of deep vein thrombosis. Among related technologies, selective brain cooling can be achieved using ordinary ice caps or nasal cooling devices, but these methods may be difficult to precisely control the temperature in practice, making it difficult to reach the target temperature at the appropriate time.

[0065] Hypothermia therapy requires prolonged maintenance, typically lasting at least 24 to 72 hours, and the rewarming process must be slow to prevent intracranial pressure rebound and other complications. Excessive rewarming can lead to systemic vasodilation, hypotension, reduced cerebral blood flow, and impaired brain function. The duration of hypothermia and the rate of rewarming can vary significantly among different patients. Currently, traditional hypothermia therapy lacks a temperature feedback control mechanism, failing to provide timely feedback and automatic adjustment to changes in the patient's body temperature. This makes precise temperature control (including hypothermia treatment and rewarming) and real-time monitoring of treatment effectiveness impossible, potentially causing secondary harm to the patient.

[0066] In view of this, this application provides a cryotherapy system that acquires temperature data through an ice cap temperature sensor, a body surface temperature sensor, and a rectal temperature sensor, and determines a target temperature control mode based on the temperature data, the patient's target treatment type, and the target temperature control type, thereby controlling the temperature control module. This ensures the accuracy of cryotherapy, meets the user's need for continuous monitoring and intelligent adjustment of the treatment cap temperature, and protects the patient to the greatest extent possible.

[0067] Please see Figure 1 The cryotherapy system 100 includes a controller 80 and a treatment cap 10, a temperature control module 20, a heat exchange unit 30, and an ice cap temperature sensor 40, all electrically connected to the controller 80. The treatment cap 10 includes a protective layer 11, a cooling layer 12, and a skin-adhesive layer 13, which are stacked together.

[0068] The temperature control module 20 is disposed between the cooling layer 12 and the skin-contact layer 13. The temperature control module 20 is used to absorb heat or release heat, that is, to absorb heat from the heat exchange unit 30 to cool down the treatment cap 10 or to release heat to the heat exchange unit 30 to heat up the treatment cap 10.

[0069] The heat exchange unit 30 is disposed between the skin-contact layer 13 and the temperature control module 20, and is in contact with the temperature control module 20. The heat exchange unit 30 includes a circulating coolant, which can transfer heat with the temperature control module 20. The heat exchange unit 30 is used to reduce or increase the internal temperature of the treatment cap 10 based on the heat transfer between the temperature control module 20 and the circulating coolant in the heat exchange unit 30.

[0070] The ice cap temperature sensor 40 is disposed on the side of the skin-contact layer 13 near the cooling layer 12. The ice cap temperature sensor 40 is used to detect the liquid temperature of the circulating coolant transmitted in the heat exchange unit 30 and send the liquid temperature of the circulating coolant to the controller 80.

[0071] Please continue reading. Figure 1 The cryotherapy system 100 also includes a body surface temperature sensor 50, an anal temperature sensor 60, and a display screen 70, which are electrically connected to the controller 80.

[0072] The body surface temperature sensor 50 is used to detect the user's body surface temperature, and the anal temperature sensor 60 is used to detect the user's anal temperature. Understandably, the body surface temperature sensor 50 and the anal temperature sensor 60 can be placed on the corresponding parts of the human body in any suitable manner. For example, the anal temperature sensor 60 can be placed inside the anus, with an external lead connected to the anal temperature sensor 60 fixed around the anus. The anal temperature sensor 60 can transmit the measured anal temperature to the controller 80 through the external lead. Of course, the body surface temperature sensor 50 and the anal temperature sensor 60 can also be placed on the corresponding parts of the human body in other suitable ways; this embodiment does not limit this approach.

[0073] The display screen 70 is used to receive the user's target temperature control type and target treatment type. The user can manually input or select the target temperature control type and target treatment type via the display screen 70, allowing the display screen 70 to receive these information. Alternatively, the user can input or select the target temperature control type and target treatment type via a smartphone, tablet, or other device and send this information to the display screen 70, enabling the display screen 70 to receive these information. Of course, the display screen 70 can also be used to display real-time information such as the current temperature (including body surface temperature, rectal temperature, and the temperature inside the treatment cap 10), the target temperature (also including body surface temperature, rectal temperature, and the temperature inside the treatment cap 10), usage time, and working status. In some optional embodiments, the display screen 70 can be an LCD screen, which is simple to operate and user-friendly.

[0074] The controller 80 determines the target temperature control mode based on the target temperature control type and the target treatment type, and controls the temperature control module 20 based on the target temperature control mode to make the temperature of the treatment cap 10 reach the target temperature.

[0075] The controller 80 is the core control unit of the cryotherapy system 100. It is responsible for receiving data detected by various sensors and the user's target temperature control type and target treatment type received by the display screen 10, and adjusting the temperature of the treatment cap 10 according to the preset temperature curve or target temperature. In some embodiments, the controller 80 may be a microcontroller (e.g., AT89C51) or other suitable control unit, device, etc., and this application embodiment does not limit it in any way.

[0076] In some implementations, the controller 80 receives the target temperature control type and target treatment type from the display screen 70. Based on the target temperature control type and target treatment type, it determines the target temperature control mode corresponding to the target temperature control type and target treatment type. The target temperature control mode includes parameters such as target temperature, duration, and temperature change rate. Based on the target temperature control mode, the controller sends a command to the temperature control module 20 to control the temperature control module 20 to work in the required working state (i.e., cooling state or warming state), such as turning the temperature control module 20 on or off, adjusting the power output of the temperature control module 20 to achieve the required heating or cooling rate, so that the temperature inside the treatment cap 10 reaches the expected target temperature.

[0077] For example, in some embodiments, if the target treatment type is traumatic brain injury and the target temperature control type is cooling, then the corresponding target temperature control mode is determined based on the traumatic brain injury and the cooling type. The target temperature control mode includes: reducing the rectal temperature to 33°C within 3 hours, decreasing by 1°C every hour, and measuring the rectal temperature every 30 minutes; during the cooling treatment for traumatic brain injury, maintaining the rectal temperature between 33-35°C.

[0078] In some embodiments, if the target treatment type is traumatic brain injury and the target temperature control type is rewarming, then a corresponding target temperature control mode is determined based on the traumatic brain injury and the rewarming type. The target temperature control mode includes: maintaining a rewarming temperature control rate that increases by 1°C every 4 hours, and restoring the rectal temperature to 36-37°C after 12 hours.

[0079] It is understood that the correspondence between the target treatment type, the target temperature control type, and the target temperature control mode can be set by the designer based on experimental data and historical data, etc., and this application embodiment does not impose any limitations on this.

[0080] Please see Figure 2 In some embodiments, the cryotherapy system 100 further includes an intracranial pressure sensor 90, an electroencephalogram (EEG) sensor 91, and a wireless communication module 92, which are electrically connected to the controller 80.

[0081] In some embodiments, the wireless communication module 92 may employ Bluetooth, Wi-Fi, NFC, or other short-range wireless communication technologies to facilitate data interaction, remote monitoring, and control with smartphones, tablets, computers, or other devices.

[0082] In some embodiments, an intracranial pressure sensor 90 is used to record fVEP signals. The intracranial pressure sensor 90 is a specific sensor used to acquire intracranial pressure signals. The intracranial pressure sensor 90 includes subcutaneous needle electrodes or implanted cranial electrodes to ensure accurate capture of the N2 wave latency. When diffuse non-modal flash stimulation is applied to the retina, these light signals are conducted through structures such as the optic nerve, optic chiasm, optic tract, and optic radiation to the primary visual cortex (V1 area) of the brain, generating potential changes in this region, which are recorded at specific locations on the scalp (usually the occipital region). The main waveforms of the fVEP signal include the N2 wave and the P2 wave, where the latency of the N2 wave is positively correlated with intracranial pressure. Therefore, this characteristic can be used to non-invasively monitor changes in intracranial pressure. When intracranial pressure increases, it can lead to damage to the visual pathway nerves, ischemia and hypoxia of neurons and fibers, metabolic disorders, and blockage of nerve electrical signal conduction, resulting in a prolonged latency of the fVEP signal peak (mainly the N2 wave), with the prolongation time being proportional to the intracranial pressure value.

[0083] The brainwave sensor 91 captures spontaneous bioelectric potentials from the cerebral cortex on the scalp. The brainwave sensor 91 can be a device similar to SenzeBand 2 and Xmuse. The brainwave sensor 91 simply needs to be attached to the scalp to detect brainwaves and can transmit the brainwave data to a smartphone, tablet, or computer for analysis via a wireless communication module 92 (e.g., Bluetooth or other wireless methods).

[0084] The ice cap temperature sensor 40, body surface temperature sensor 50, and anal temperature sensor 60 are used to monitor the temperature of the treatment cap and the human body in real time. The temperature data from the ice cap temperature sensor 40, body surface temperature sensor 50, and anal temperature sensor 60 can be transmitted via wireless communication module 92 to remote monitoring devices, smartphones, tablets, computers, etc. A lower temperature alarm value can also be set (e.g., anal temperature cannot be lower than 32°C), and an automatic alarm will sound when the body temperature is lower than or equal to the lower alarm value. For anal temperature measurement, in some embodiments, a position sensor similar to an anal suppository can be used.

[0085] Temperature control types include cooling type and reheating type, and temperature control modes include cooling mode and reheating mode.

[0086] In some embodiments, the controller 80 responds to the target temperature control type as a cooling type and determines the cooling mode that matches the target treatment type as the target temperature control mode from a plurality of preset cooling modes.

[0087] In some embodiments, the controller 80 responds to the target temperature control type as a rewarming type and determines the rewarming mode that matches the target treatment type as the target temperature control mode among a plurality of preset rewarming modes.

[0088] In some implementations, the controller 80 determines the target temperature control type as a cooling type, and based on the target treatment type, determines the cooling mode that matches the target treatment type from among a number of pre-set cooling modes as the target temperature control mode.

[0089] In some implementations, the controller 80 determines the target temperature control type as a rewarming type, and based on the target treatment type, determines the cooling mode that matches the target treatment type from among a number of pre-set rewarming modes as the target temperature control mode.

[0090] In some embodiments, the treatment type corresponds to the injury or illness to be treated. The injury or illness to be treated includes, but is not limited to, brain protection during cardiac surgery cardiopulmonary bypass, traumatic brain injury related to decreased cerebral perfusion pressure, post-CPR encephalopathy, neonatal hypoxic-ischemic encephalopathy, traumatic brain injury (e.g., traumatic brain injury, cerebral edema following extensive cerebral contusion and laceration hemorrhage, etc.), acute status epilepticus, ischemic stroke, cerebral hemorrhage, subarachnoid hemorrhage, and various febrile states (e.g., central febrile illness, febrile seizures, encephalitis, etc.).

[0091] In some embodiments, if the user inputs or selects the target treatment type as febrile seizure and the target temperature control type as the cooling type, the cooling mode that matches the febrile seizure can be determined as the target temperature control mode from a plurality of preset cooling modes, based on the target treatment type of febrile seizure.

[0092] In some embodiments, if the user inputs or selects a target treatment type of traumatic brain injury and a target temperature control type of rewarming, the target temperature control mode can be determined from a plurality of pre-set rewarming modes based on the target treatment type of traumatic brain injury.

[0093] In some embodiments, the controller 80 determines temperature control information corresponding to the target temperature control mode, the temperature control information including the target temperature.

[0094] In some embodiments, the controller 80 performs filtering on multiple body surface temperatures and multiple anal temperatures based on the Kalman filter algorithm to obtain the target body surface temperature and the target anal temperature.

[0095] In some embodiments, the controller 80 determines a temperature that matches the target treatment type as the target monitoring temperature between the target body surface temperature and the target anal temperature.

[0096] In some embodiments, the controller 80 controls the temperature control module based on the target temperature and the target monitored temperature.

[0097] In some implementations, the controller 80 extracts the corresponding temperature control information from the target temperature control mode that matches the target treatment type and the target temperature control type. The temperature control information includes the target temperature, which is the temperature that the treatment cap 10 is controlled to reach.

[0098] The Kalman filter algorithm is a mathematical algorithm used to estimate the state of a dynamic system. It combines a predictive model of the system with actual observation data; that is, it performs continuous weighted calculations based on the optimal estimate from the previous moment and the measured value at the current moment, progressively updating the estimated system state. The Kalman filter algorithm primarily combines measured values ​​from temperature sensors with theoretical values ​​to solve for the true temperature value, effectively filtering out data noise during the data acquisition process to obtain more accurate target body surface temperature and target rectal temperature more quickly.

[0099] In some implementations, the controller 80 filters multiple body surface temperatures based on a Kalman filter algorithm to obtain the target body surface temperature:

[0100] 1) Set the state variable Xt to represent the actual body surface temperature value at the current time t, and Zt to represent the body surface temperature measurement value obtained by the body surface temperature sensor 50 at the current time t (i.e., temperature data with noise).

[0101] 2) Initialize the parameters of the Kalman filter, including initializing the state estimate X0, error covariance P0, noise covariance Q, and measurement noise covariance R. The state estimate X0 can be initialized using the first measurement value (i.e., the first body surface temperature measurement value) or its average value (i.e., the average value of body surface temperature measurements). The error covariance P0 is set to a large value to represent the uncertainty of the initial estimate X0. The noise covariance Q can be set according to the characteristics of the measured temperature data to represent the uncertainty of the process model. The measurement noise covariance R is determined experimentally to represent the noise level of the measured value.

[0102] 3) Prediction phase: In each time step t, X is estimated based on the state of the previous time step. t-1 Perform state prediction to obtain the predicted state estimate X at the current time step t. t|t-1 Wherein, the predicted state estimate X at the current time step t|t-1 =State estimate of the previous time step X t-1 Based on the error covariance P of the previous time step t-1 The error covariance is predicted by combining the noise covariance Q, and the prediction error covariance P at the current time step t is obtained. t|t-1 Wherein, the predicted state estimate P at the current time step t|t-1 = Error covariance P of the previous time step t-1 +noise covariance Q.

[0103] 4) Update phase: Based on the prediction error covariance P at the current time step t t|t-1 And measure the noise covariance R, calculate the Kalman gain Kt, where Kt = prediction error covariance P at the current time step t. t|t-1 / (Prediction error covariance P at current time step t) t|t-1 +Measurement noise covariance R); Estimate X based on Kalman gain Kt and the predicted state at the current time step t. t|t-1 The body surface temperature measurement Zt at the current time step t is used to update the state estimate X at the current time step t. t Wherein, the state estimate X at the current time step t t =Predicted state estimate X at current time step t t|t-1 +Kalman gain Kt*(surface temperature measurement at current time step t Zt - predicted state estimate at current time step t X) t|t-1 Based on the Kalman gain Kt and the prediction error covariance P at the current time step t t|t-1 Update the error covariance P at the current time step t. t Wherein, the error covariance P at the current time step t t = (1 - Kalman gain Kt) * prediction error covariance P at current time step t t|t-1 .

[0104] 5) Determining the stage: State estimation X at the last time step t This refers to the target body surface temperature obtained after filtering.

[0105] Similarly, the controller 80 can also filter multiple anal temperatures based on the Kalman filter algorithm in the above manner to obtain the target anal temperature. The embodiments of this application will not be described in detail here.

[0106] In some implementations, the controller 80 determines the target body surface temperature or the target anal temperature as the target monitoring temperature between the target body surface temperature and the target anal temperature, based on the target treatment type. In other words, the target monitoring temperature for specific monitoring and adjustment is determined to be the target body surface temperature or the target anal temperature.

[0107] For example, in some embodiments, rectal temperature needs to be monitored in the user's target treatment type (e.g., traumatic brain injury) to accurately control the temperature for hypothermia treatment and rewarming. Therefore, when the target treatment type is traumatic brain injury, the target rectal temperature is the target monitoring temperature; that is, the specific monitoring and adjustment target temperature is the target rectal temperature.

[0108] In some implementations, the controller 80 subtracts the target monitoring temperature from the target temperature to obtain a temperature difference. Based on this temperature difference, the controller controls the operating state of the temperature control module 20, such as turning the module on or off, or adjusting its power output to achieve the desired heating or cooling rate. Specifically, if the temperature difference is greater than 0, it indicates that the target temperature is higher than the target monitoring temperature, requiring heating; if the temperature difference is less than 0, it indicates that the target temperature is lower than the target monitoring temperature, requiring cooling; and if the temperature difference is equal to 0, it indicates that the target temperature is equal to the target monitoring temperature, maintaining the target monitoring temperature unchanged.

[0109] In some embodiments, to avoid frequent switching and adjustment of the temperature control module 20, a temperature control threshold β can be set to define when the temperature control module 20 needs to be adjusted. Specifically, when the absolute value of the temperature difference is greater than the temperature control threshold β, it indicates that the temperature control module 20 needs to be adjusted for temperature regulation; when the absolute value of the temperature difference is less than or equal to the temperature control threshold β, it indicates that the temperature control module 20 does not need to be adjusted, and the temperature control module 20 maintains its current operating state.

[0110] Temperature control information also includes temperature maintenance time, which refers to the duration for which the treatment cap 10 needs to be maintained at the target temperature.

[0111] In some embodiments, the controller 80 determines whether the target monitoring temperature is equal to the target temperature.

[0112] In some embodiments, if the temperature is equal to the target temperature, the controller 80 controls the temperature control module to maintain the temperature inside the treatment cap at the target temperature according to the temperature maintenance time.

[0113] In some embodiments, if the temperature is not equal to the target temperature, the controller 80 controls the temperature control module to adjust the temperature inside the treatment cap so that the temperature inside the treatment cap is equal to the target temperature.

[0114] In some implementations, the controller 80 compares the target monitored temperature with the target temperature to determine whether the target monitored temperature is equal to the target temperature. For example, in some embodiments, if the target monitored temperature is a target body surface temperature, the target body surface temperature is compared with the target temperature to determine whether the target body surface temperature is equal to the target temperature.

[0115] In some implementations, if the comparison determines that the target monitoring temperature is equal to the target temperature, the controller 80 does not adjust the temperature control module 20 and controls the temperature control module 20 to maintain its current working state, so as to maintain the temperature inside the treatment cap 10 equal to the target temperature, until the time for maintaining the temperature inside the treatment cap 10 equal to the target temperature reaches the temperature maintenance time.

[0116] Understandably, designers can set the temperature maintenance time according to different patients, different treatment types, and different temperature control types. For example, in some embodiments, the target treatment type is acute epilepsy. After the patient's epileptic seizures stop, the body surface temperature needs to be lowered to the target temperature of 31-35°C and maintained at this target temperature for 24-48 hours. In this case, the temperature maintenance time is set to any time value within 24-48 hours.

[0117] In some implementations, if the target monitoring temperature is not equal to the target temperature, the controller 80 dynamically adjusts the heating or cooling power output of the temperature control module 20 based on the difference between the target temperature and the current temperature inside the treatment cap 10, so that the temperature inside the treatment cap 10 is equal to the target temperature.

[0118] The temperature control information also includes time limit information for the temperature inside the treatment cap to reach the target temperature, that is, the temperature control module 20 needs to be controlled to heat up or cool down to the target temperature within a limited time.

[0119] In some embodiments, the controller 80 determines a reference monitoring temperature before the user wears the treatment cap, wherein the reference monitoring temperature matches the target treatment type;

[0120] In some embodiments, the controller 80 calculates the absolute value of the difference between the reference monitoring temperature and the target temperature to obtain the temperature difference.

[0121] In some embodiments, the controller 80 calculates the target temperature control rate based on temperature difference and time limit information.

[0122] In some embodiments, the controller 80 controls the temperature control module to adjust the temperature inside the treatment cap based on the target temperature control rate, so that the temperature inside the treatment cap is equal to the target temperature.

[0123] In some implementations, before the user puts on the treatment cap 10, the controller 80 determines a reference monitoring temperature in the treatment cap 10 that matches the current target treatment type, based on the current target treatment type.

[0124] For example, in some embodiments, the current target treatment type of the treatment cap 10 is encephalitis, where the reference monitoring temperature matching encephalitis is 31-34°C. Therefore, it can be determined that the reference monitoring temperature before the user wears the treatment cap is the monitoring temperature of 31-34°C matching encephalitis.

[0125] In some implementations, the controller 80 calculates the difference between the reference monitoring temperature and the target temperature to obtain a temperature difference value, and then takes the absolute value of the temperature difference value to obtain the temperature difference between the reference monitoring temperature and the target temperature, wherein the temperature difference is a positive value or a zero value.

[0126] In some implementations, the controller 80 divides the temperature difference by the time limit information (how long it takes to control the temperature inside the treatment cap 10 to reach the target temperature) to obtain the target temperature control rate, wherein the unit of the target temperature control rate may be temperature change per minute (e.g., °C / min), temperature change per hour (e.g., °C / h), or other suitable temperature change representation.

[0127] It is understandable that when the temperature difference is zero, the target temperature control rate is zero. Therefore, it is not necessary to control the temperature control module 20 to adjust the temperature inside the treatment cap based on the target temperature control rate. It is only necessary to maintain the current working state of the temperature control module 20 unchanged.

[0128] In some implementations, if the target temperature is higher than the reference monitoring temperature, the controller 80 controls the temperature control module 20 to heat the inside of the treatment cap 10 at the target temperature control rate, so that the temperature inside the treatment cap 10 reaches the target temperature, and maintains the temperature inside the treatment cap 10 at the target temperature; if the target temperature is lower than the reference monitoring temperature, the controller 80 controls the temperature control module 20 to cool the inside of the treatment cap 10 at the target temperature control rate, so that the temperature inside the treatment cap 10 reaches the target temperature, and maintains the temperature inside the treatment cap 10 at the target temperature.

[0129] In some embodiments, the temperature control module 20 is a Peltier module, also known as a thermoelectric cooler, which is a device that uses the thermoelectric effect for cooling or heating. A Peltier module is composed of two different semiconductor materials (typically N-type and P-type) to conduct electrons and holes, respectively. When a direct current is applied to the Peltier module, electrons migrate from a high energy level to a low energy level in the N-type semiconductor material, and holes migrate from a high energy level to a low energy level in the P-type semiconductor material. In the N-type semiconductor material, the migration of electrons causes one side to absorb heat, making it cooler; while in the P-type semiconductor material, the migration of holes causes the other side to release heat, making it hotter, resulting in one side of the Peltier module absorbing heat and the other side releasing heat. By controlling the direction of the current, cooling or heating can be achieved; that is, changing the direction of the current interchanges the cold and hot sides of the Peltier module, thereby achieving different temperature control effects.

[0130] In some embodiments, the controller 80 calculates the target drive current based on the target temperature control rate.

[0131] In some embodiments, the controller 80 controls the target drive current to be transmitted to the Peltier module in the direction of the target current corresponding to the target temperature control type, so that the temperature inside the treatment cap is equal to the target monitoring temperature.

[0132] In some implementations, the controller 80 obtains the magnitude of the target drive current based on the system characteristics and the heat conduction equation. The target drive current I = proportional coefficient K * target temperature control rate R. The proportional coefficient K is a proportional constant related to the system characteristics (e.g., the thermal performance of the Peltier module), which can be set by the designer according to the system characteristics. This application embodiment does not limit it in any way.

[0133] In some implementations, the controller 80 determines the direction of the target current, i.e. the direction of the target drive current, according to the target temperature control type, and applies the target drive current in the target current direction to the Peltier module, thereby transmitting the target drive current in the target current direction to the Peltier module, so that the Peltier module operates to heat up or cool down according to the target current direction, and by adjusting the magnitude of the target drive current, the temperature inside the treatment cap 10 reaches the target temperature, and after reaching the target temperature, the temperature inside the treatment cap 10 is maintained at the target temperature.

[0134] In some embodiments, if the target temperature control type is cooling type, the target drive current should be positive (i.e., positive current direction), indicating that the Peltier module is operating in cooling mode; if the target temperature control type is heating type, the target drive current should be negative (i.e., negative current direction), indicating that the Peltier module is operating in heating mode.

[0135] In some embodiments, the controller 80 responds to the target temperature control type as cooling type and determines the first current direction as the target current direction.

[0136] In some embodiments, the controller 80 responds to the target temperature control type being the rewarming type and determines the second current direction as the target current direction, the second current direction being opposite to the first current direction.

[0137] In some implementations, the controller 80 sets the logical representation of the current direction. For example, it sets the cooling type as the first current direction, and the first current direction is a positive current direction (positive value). When the target temperature control type is determined to be cooling, the first current direction is determined to be the target current direction. At this time, the Peltier module operates in cooling mode.

[0138] In some implementations, the controller 80 sets the rewarming type to the second current direction, and this second current direction is a negative current direction (negative value). Clearly, the second current direction is opposite to the first current direction. When the target temperature control type is rewarming, the second current direction is determined as the target current direction. At this time, the Peltier module operates in heating mode. Through the above method, the current direction is determined according to the target temperature control type to control the Peltier module to operate correctly in cooling and rewarming modes.

[0139] In some embodiments, the controller 80 acquires a current library that matches the target treatment type, wherein the current library includes a plurality of temperature control rates and a current corresponding to each temperature control rate.

[0140] In some embodiments, the controller 80 finds the current corresponding to the target temperature control rate in the current library as the target drive current.

[0141] It is understood that designers can design and determine multiple temperature control rates and corresponding currents for each temperature control rate to form a current pool, based on different patients, different treatment types, and different temperature control types. This application does not impose any limitations on this. Specifically, to facilitate the acquisition of the current pool and rapid temperature adjustment, several current pools corresponding to several target treatment types are designed, with the target treatment type as a design objective.

[0142] For example, in some embodiments, if the target treatment type is post-CPR encephalopathy, then multiple temperature control rates and corresponding currents for each temperature control rate can be designed to obtain a current library corresponding to post-CPR encephalopathy. For example, the current library corresponding to post-CPR encephalopathy includes: four temperature control rates, namely 1℃ / 30min, 1℃ / 120min, 1.5℃ / 6h, and 2℃ / 24h, wherein the current magnitudes corresponding to 1℃ / 30min, 1℃ / 120min, 1.5℃ / 6h, and 2℃ / 24h are 80mA, 50mA, 10mA, and 5mA, respectively.

[0143] In some implementations, the controller 80 obtains a current library matching the target treatment type, resulting in multiple temperature control rates and a current corresponding to each temperature control rate. Each target treatment type corresponds to one current library.

[0144] In some implementations, the controller 80 traverses the temperature control rates in the current library based on the previously calculated target temperature control rate, searches for the current corresponding to the target temperature control rate in the current library that matches the target treatment type, and after finding the current corresponding to the target temperature control rate, uses the current as the target driving current and transmits it to the temperature control module 20 to control the temperature control module 20 to work and adjust the temperature inside the treatment cap 10 to equal the target temperature.

[0145] In some embodiments, if no current corresponding to the target temperature control rate is found in the current library, a linear function can be determined using a relevant algorithm based on the temperature control rate in the current library and the current corresponding to the temperature control rate. Then, the target driving current can be calculated using the linear function based on the target temperature control rate.

[0146] In some embodiments, the controller 80 determines a target rate range based on the current pool, the target rate range being jointly defined by a first temperature control rate and a second temperature control rate, and the target temperature control rate being within the target rate range.

[0147] In some embodiments, the controller 80 determines the current corresponding to the first temperature control rate as the first current and the current corresponding to the second temperature control rate as the second current.

[0148] In some embodiments, the controller 80 generates a target linear function based on a linear interpolation algorithm, a first temperature control rate, a second temperature control rate, a first current, and a second current. The target linear function is a function with the temperature control rate as the independent variable and the current as the dependent variable.

[0149] In some embodiments, the controller 80 calculates the target drive current based on the target linear function and the target temperature control rate.

[0150] In some implementations, the controller 80 searches the current library for a first temperature control rate and a second temperature control rate that are closest to the target temperature control rate. Based on the magnitude of the first and second temperature control rates, the controller 80 defines a target rate range by combining the first and second temperature control rates. This target rate range is either from the first temperature control rate to the second temperature control rate (when the first temperature control rate is less than the second temperature control rate), or from the second temperature control rate to the first temperature control rate (when the first temperature control rate is greater than the second temperature control rate). Clearly, the target temperature control rate falls within the target rate range, i.e., between the first and second temperature control rates or between the second and first temperature control rates.

[0151] In some implementations, the controller 80 determines the current corresponding to the first temperature control rate from the current library as the first current based on the first temperature control rate; and determines the current corresponding to the second temperature control rate from the current library as the second current based on the second temperature control rate.

[0152] In some implementations, the controller 80 constructs a linear interpolation formula, wherein the linear interpolation formula is:

[0153]

[0154] In the above formula, R1 refers to the first temperature control rate, R2 refers to the second temperature control rate, I1 refers to the first current corresponding to the first temperature control rate, I2 refers to the second current corresponding to the second temperature control rate, and f(R) refers to the objective linear function. Given the temperature control rate R, the current value at the temperature control rate R can be calculated through the objective linear function f(R).

[0155] Substituting the first temperature control rate, the second temperature control rate, the first current, and the second current into the above formula, the target linear function f(R) is generated. The target linear function f(R) is a function with the temperature control rate R as the independent variable and the current value I as the dependent variable.

[0156] In some implementations, the controller 80 sets the target temperature control rate R. C Substituting into the objective linear function f(R) above, the current value I = f(R) is calculated. C That is, the target driving current is the current value I = f(R). C ).

[0157] This application also provides a control method for a cryotherapy system. This control method is applied to the cryotherapy system 100 described in the above embodiments. Please refer to [link / reference]. Figure 3 The control method of the cryotherapy system includes the following steps:

[0158] S31: Determine the target temperature control mode based on the target temperature control type and the target treatment type.

[0159] S32: Temperature control module based on target temperature control mode.

[0160] In some embodiments, the temperature control type includes a cooling type and a rewarming type, and the temperature control mode includes a cooling mode and a rewarming mode. Determining the target temperature control mode based on the target temperature control type and the target treatment type includes: responding to the target temperature control type being a cooling type, determining the cooling mode that matches the target treatment type from a plurality of preset cooling modes as the target temperature control mode; or, responding to the target temperature control type being a rewarming type, determining the rewarming mode that matches the target treatment type from a plurality of preset rewarming modes as the target temperature control mode.

[0161] In some embodiments, controlling the temperature control module based on the target temperature control mode includes: determining temperature control information corresponding to the target temperature control mode, the temperature control information including a target temperature; filtering multiple body surface temperatures and multiple anal temperatures based on a Kalman filter algorithm to obtain a target body surface temperature and a target anal temperature; determining a temperature between the target body surface temperature and the target anal temperature that matches the target treatment type as a target monitoring temperature; and controlling the temperature control module according to the target temperature and the target monitoring temperature.

[0162] In some embodiments, the temperature control information further includes a temperature maintenance time. The temperature control module is controlled according to the target temperature and the target monitoring temperature, including: determining whether the target monitoring temperature is equal to the target temperature; if they are equal, controlling the temperature control module to maintain the temperature inside the treatment cap at the target temperature according to the temperature maintenance time; if they are not equal, controlling the temperature control module to adjust the temperature inside the treatment cap so that the temperature inside the treatment cap is equal to the target temperature.

[0163] In some embodiments, the temperature control information also includes time limit information for the temperature inside the treatment cap to reach the target temperature. The control method of the cryogenic treatment system further includes: determining a reference monitoring temperature before the user wears the treatment cap, wherein the reference monitoring temperature matches the target treatment type, calculating the absolute value of the difference between the reference monitoring temperature and the target temperature to obtain the temperature difference, calculating the target temperature control rate based on the temperature difference and the time limit information, and controlling the temperature control module to adjust the temperature inside the treatment cap based on the target temperature control rate so that the temperature inside the treatment cap is equal to the target temperature.

[0164] In some embodiments, the temperature control module is a Peltier module. Controlling the temperature control module to adjust the temperature inside the treatment cap based on the target temperature control rate so that the temperature inside the treatment cap is equal to the target temperature includes: calculating the target drive current based on the target temperature control rate, and controlling the target drive current to be transmitted to the Peltier module in the direction of the target current corresponding to the target temperature control type so that the temperature inside the treatment cap is equal to the target temperature.

[0165] In some embodiments, the control method of the cryotherapy system further includes: responding to a target temperature control type of cooling, determining a first current direction as a target current direction, responding to a target temperature control type of warming, determining a second current direction as a target current direction, wherein the second current direction is opposite to the first current direction.

[0166] In some embodiments, calculating the target drive current based on the target temperature control rate includes: obtaining a current library that matches the target treatment type, wherein the current library includes multiple temperature control rates and a current corresponding to each temperature control rate, and finding the current corresponding to the target temperature control rate in the current library as the target drive current.

[0167] In some embodiments, finding the current corresponding to the target temperature control rate in the current library as the target driving current includes: determining a target rate range based on the current library, the target rate range being jointly defined by a first temperature control rate and a second temperature control rate, the target temperature control rate being within the target rate range; determining the current corresponding to the first temperature control rate as the first current and the current corresponding to the second temperature control rate as the second current; generating a target linear function based on a linear interpolation algorithm, the first temperature control rate, the second temperature control rate, the first current, and the second current, the target linear function being a function with the temperature control rate as the independent variable and the current as the dependent variable; and calculating the target driving current based on the target linear function and the target temperature control rate.

[0168] This application embodiment also provides a control device for a cryotherapy system, which is connected to a controller 80 for controlling the cryotherapy system 100. Alternatively, the control device for the cryotherapy system can be configured within the controller 80 to control the cryotherapy system 100.

[0169] Please see Figure 4 , Figure 4 A schematic diagram of the structure of the control device 200 of the cryotherapy system provided in an embodiment of this application is shown.

[0170] like Figure 4 As shown, the control device 200 of the cryotherapy system includes:

[0171] Module 210 is used to determine the target temperature control mode based on the target temperature control type and the target treatment type;

[0172] Control module 220 is used to control the temperature control module based on the target temperature control mode.

[0173] In some embodiments, the temperature control type includes cooling type and reheating type, and the temperature control mode includes cooling mode and reheating mode. The determining module 210 is specifically used for:

[0174] If the target temperature control type is cooling, the target temperature control mode is selected from multiple preset cooling modes to match the target treatment type; or,

[0175] If the target temperature control type is rewarming, the rewarming mode that matches the target treatment type will be selected as the target temperature control mode from among several preset rewarming modes.

[0176] In some embodiments, the control module 220 is further configured to:

[0177] Determine the temperature control information corresponding to the target temperature control mode, including the target temperature;

[0178] Based on the Kalman filter algorithm, multiple body surface temperatures and multiple anal temperatures are filtered to obtain the target body surface temperature and the target anal temperature.

[0179] Determine the target monitoring temperature as the temperature that matches the target treatment type between the target body surface temperature and the target anal temperature;

[0180] The temperature control module is controlled based on the target temperature and the target monitored temperature.

[0181] In some embodiments, the temperature control information further includes a temperature maintenance time, and the control module 220 is specifically used for:

[0182] Determine if the monitored temperature is equal to the target temperature.

[0183] If the temperature is equal to the target temperature, the temperature control module will maintain the temperature inside the treatment cap at the target temperature according to the temperature maintenance time.

[0184] If the temperature is not equal to the target temperature, the temperature control module will adjust the temperature inside the treatment cap to make the temperature inside the treatment cap equal to the target temperature.

[0185] In some embodiments, the temperature control information further includes time limit information for the temperature inside the treatment cap to reach the target temperature, and the control module 220 is further configured to:

[0186] Determine the reference monitoring temperature before the user puts on the treatment cap, where the reference monitoring temperature matches the target treatment type;

[0187] The absolute value of the difference between the reference monitoring temperature and the target temperature is used to obtain the temperature difference.

[0188] The target temperature control rate is calculated based on temperature difference and time-limited information;

[0189] The temperature control module adjusts the temperature inside the treatment cap based on the target temperature control rate, so that the temperature inside the treatment cap is equal to the target temperature.

[0190] In some embodiments, the temperature control module is a Peltier module, and the control module 220 is further used for:

[0191] Calculate the target drive current based on the target temperature control rate;

[0192] The target drive current is transmitted to the Peltier module in the direction of the target current corresponding to the target temperature control type, so that the temperature inside the treatment cap is equal to the target temperature.

[0193] In some embodiments, the control module 220 is further configured to:

[0194] The target temperature control type is cooling, and the first current direction is determined to be the target current direction.

[0195] The target temperature control type is a rewarming type, and the direction of the second current is determined to be the target current direction. The direction of the second current is opposite to the direction of the first current.

[0196] In some embodiments, the control module 220 is further configured to:

[0197] Obtain a current library that matches the target treatment type, wherein the current library includes multiple temperature control rates and the current corresponding to each temperature control rate;

[0198] Find the current in the current library that corresponds to the target temperature control rate as the target drive current.

[0199] In some embodiments, the control module 220 is further configured to:

[0200] The target rate range is determined based on the current pool. The target rate range is jointly defined by the first temperature control rate and the second temperature control rate. The target temperature control rate is within the target rate range.

[0201] The current corresponding to the first temperature control rate is determined as the first current, and the current corresponding to the second temperature control rate is determined as the second current;

[0202] Based on the linear interpolation algorithm, a target linear function is generated using the first temperature control rate, the second temperature control rate, the first current, and the second current. The target linear function is a function with the temperature control rate as the independent variable and the current as the dependent variable.

[0203] The target drive current is calculated based on the target linear function and the target temperature control rate.

[0204] It is understood that the control device 200 of the cryotherapy system provided in the embodiments of this application can be a software module. The software module includes several instructions, which are stored in a memory. The processor can access the memory and call the instructions to execute them in order to complete the control method of the cryotherapy system described in the above embodiments.

[0205] In some implementations, the control device 200 of the cryotherapy system can also be constructed from hardware devices. For example, the control device 200 of the cryotherapy system can be constructed from one or more chips, which can work in coordination to complete the control method of the cryotherapy system described in the above embodiments. As another example, the control device 200 of the cryotherapy system can also be constructed from various logic devices, such as general-purpose processors, digital signal processors (DSPs), application-specific integrated circuits (ASICs), field-programmable gate arrays (FPGAs), microcontrollers, ARM (Acorn RISC Machine) or other programmable logic devices, discrete gate or transistor logic, discrete hardware components, or any combination of these components.

[0206] It should be noted that the control device 200 of the aforementioned cryotherapy system can execute the control method of the cryotherapy system provided in the embodiments of this application, and has the corresponding functional modules and beneficial effects for executing the method. Technical details not described in detail in the embodiments of the control device 200 of the cryotherapy system can be found in the control method of the cryotherapy system provided in the embodiments of this application.

[0207] This application also provides a controller that can be used in a cryotherapy system 100. See also... Figure 5 , Figure 5 A schematic diagram of the controller 80 in the cryotherapy system 100 provided in this application embodiment is shown.

[0208] like Figure 5 As shown, the controller 80 includes one or more processors 801 and a memory 802. The memory 802 is connected to one or more processors 801, for example, via a bus.

[0209] Processor 801 is configured to support controller 80 in performing the corresponding functions in the methods described in the above method embodiments. Processor 801 may be a central processing unit (CPU), a network processor (NP), a hardware chip, or any combination thereof. The aforementioned hardware chip may be an application-specific integrated circuit (ASIC), a programmable logic device (PLD), or a combination thereof. The aforementioned PLD may be a complex programmable logic device (CPLD), a field-programmable gate array (FPGA), a generic array logic (GAL), or any combination thereof.

[0210] Memory 802 is used to store program code, etc. Memory 802 may include volatile memory (VM), such as random access memory (RAM); memory 802 may also include non-volatile memory (NVM), such as read-only memory (ROM), flash memory, hard disk drive (HDD), or solid-state drive (SSD); memory may also include combinations of the above types of memory.

[0211] The memory 802 can be used to store non-volatile software programs, non-volatile computer-executable programs, and modules, such as the program instructions / modules corresponding to the control method of the cryotherapy system in the embodiments of this application. The processor 801 executes the control method of the cryotherapy system and various functional applications and data processing of the control device 200 of the cryotherapy system by running the non-volatile software programs, instructions, and modules stored in the memory 802, thereby realizing the control method of the cryotherapy system and the functions of the control device 200 of the cryotherapy system provided in the above method embodiments.

[0212] The memory 802 may include a program storage area and a data storage area, wherein the program storage area may store the operating system and application programs required for at least one function. The data storage area may store data created based on the use of the control device 200 of the cryotherapy system. In some embodiments, the memory may optionally include memory remotely located relative to the processor, which can be connected to the control device 200 of the cryotherapy system via a network. Examples of such networks include, but are not limited to, the Internet, intranets, local area networks, mobile communication networks, and combinations thereof.

[0213] One or more modules are stored in memory 802. When executed by one or more processors 801, they execute the control method of the cryotherapy system in any of the above method embodiments. For example, they execute the method steps described in the above method embodiments to realize the functions of the modules described in the above device embodiments.

[0214] This application also provides a computer-readable storage medium storing a computer program, which includes program instructions. When the program instructions are executed by the controller 80, the controller 80 performs the control method of the cryotherapy system as described in the foregoing method embodiments.

[0215] It should be noted that in the above embodiments, there is no necessarily a certain order between the steps. Those skilled in the art can understand from the description of the embodiments of this application that the above steps may have different execution orders in different embodiments, that is, they may be executed in parallel or in turn, etc.

[0216] Those skilled in the art will understand that all or part of the processes in the above embodiments can be implemented by a computer program instructing related hardware. The program can be stored in a computer-readable storage medium, and when executed, it can include the processes of the embodiments of the above methods. The storage medium can be a magnetic disk, optical disk, read-only memory (ROM), or random access memory (RAM), etc.

[0217] The above-disclosed embodiments are merely preferred embodiments of this application and should not be construed as limiting the scope of this application. Therefore, any equivalent variations made in accordance with the claims of this application shall still fall within the scope of this application.

Claims

1. A cryotherapy system, characterized in that, include: The treatment cap includes a layered protective layer, a cooling layer, and a skin-adhesive layer; A temperature control module is disposed between the cooling layer and the skin-contact layer and is configured to absorb or release heat. A heat exchange unit is disposed between the skin-contact layer and the temperature control module and is in contact with the temperature control module. It is configured to reduce or increase the temperature inside the treatment cap based on the heat transfer between the temperature control module and the heat exchange unit. An ice cap temperature sensor is disposed on the side of the skin-contact layer near the cooling layer and is configured to detect the liquid temperature of the coolant transferred by the heat exchange unit; A body surface temperature sensor is configured to detect the user's body surface temperature; An anal temperature sensor is configured to detect the user's anal temperature; The display screen is configured to receive the target temperature control type and the target treatment type. The controller, which is electrically connected to the temperature control module, the ice cap temperature sensor, the body surface temperature sensor, the anal temperature sensor, and the display screen, is configured to: determine a target temperature control mode based on the target temperature control type and the target treatment type, and control the temperature control module based on the target temperature control mode.

2. The cryotherapy system according to claim 1, characterized in that, Temperature control types include cooling type and reheating type, and temperature control modes include cooling mode and reheating mode. The controller is configured as follows: In response to the target temperature control type being a cooling type, the cooling mode matching the target treatment type is determined from a set of preset cooling modes as the target temperature control mode; or, In response to the target temperature control type being a rewarming type, the rewarming mode that matches the target treatment type is determined as the target temperature control mode from among a plurality of preset rewarming modes.

3. The cryotherapy system according to claim 2, characterized in that, The controller is configured to: Determine the temperature control information corresponding to the target temperature control mode, wherein the temperature control information includes the target temperature; Based on the Kalman filter algorithm, the multiple body surface temperatures and multiple anal temperatures are filtered to obtain the target body surface temperature and the target anal temperature. A temperature matching the target treatment type is determined between the target body surface temperature and the target anal temperature as the target monitoring temperature; The temperature control module is controlled based on the target temperature and the target monitored temperature.

4. The cryotherapy system according to claim 3, characterized in that, The temperature control information also includes the temperature maintenance time, and the controller is configured to: Determine whether the target monitored temperature is equal to the target temperature; If the temperature is equal to the target temperature, then the temperature control module will maintain the temperature inside the treatment cap at the target temperature according to the temperature maintenance time. If the temperature is not equal to the target temperature, the temperature control module is controlled to adjust the temperature inside the treatment cap so that the temperature inside the treatment cap is equal to the target temperature.

5. The cryotherapy system according to claim 4, characterized in that, The temperature control information also includes time limit information for the temperature inside the treatment cap to reach the target temperature, and the controller is configured to: Determine a reference monitoring temperature before the user wears the treatment cap, wherein the reference monitoring temperature matches the target treatment type; The absolute value of the difference between the reference monitoring temperature and the target temperature is calculated to obtain the temperature difference; The target temperature control rate is calculated based on the temperature difference and the time limit information; Based on the target temperature control rate, the temperature control module adjusts the temperature inside the treatment cap so that the temperature inside the treatment cap equals the target temperature.

6. The cryotherapy system according to claim 5, characterized in that, The temperature control module is a Peltier module, and the controller is configured as follows: Calculate the target drive current based on the target temperature control rate; The target driving current is controlled to be transmitted to the Peltier module in the direction of the target current corresponding to the target temperature control type, so that the temperature inside the treatment cap is equal to the target temperature.

7. The cryotherapy system according to claim 6, characterized in that, The controller is configured to: In response to the target temperature control type being cooling type, the first current direction is determined as the target current direction; In response to the target temperature control type being a rewarming type, the second current direction is determined as the target current direction, which is opposite to the first current direction.

8. The cryotherapy system according to claim 6, characterized in that, The controller is configured to: Obtain a current library that matches the target treatment type, wherein the current library includes multiple temperature control rates and a current corresponding to each temperature control rate; The current corresponding to the target temperature control rate is found in the current library and used as the target drive current.

9. The cryotherapy system according to claim 8, characterized in that, The controller is configured to: The target rate range is determined based on the current pool, and the target rate range is jointly defined by the first temperature control rate and the second temperature control rate, wherein the target temperature control rate is within the target rate range. The current corresponding to the first temperature control rate is determined as the first current, and the current corresponding to the second temperature control rate is determined as the second current; A target linear function is generated based on a linear interpolation algorithm, the first temperature control rate, the second temperature control rate, the first current, and the second current. The target linear function is a function with the temperature control rate as the independent variable and the current as the dependent variable. The target driving current is calculated based on the target linear function and the target temperature control rate.

10. The cryotherapy system according to any one of claims 1 to 9, characterized in that, Also includes: An intracranial pressure sensor is electrically connected to the controller; and / or, An electroencephalogram (EEG) sensor is electrically connected to the controller. And / or, The wireless communication module is electrically connected to the controller.

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