Traditional Chinese medicine plaster for treating pain and use method thereof

Abstract

The invention discloses a traditional Chinese medicine plaster for treating pain and a use method thereof, and belongs to the technical field of traditional Chinese medicine external preparations. The plaster is composed of 10 g of unprocessed radix aconiti lateralis, 10 g of unprocessed rhizoma pinelliae, 10 g of semen brassicae, 10 g of fructus evodiae, 10 g of sulfur and 5 g of borneol, the total weight is 55 g, the plaster can be divided into 55 parts, the raw materials form the unique formula, no other components are added, all the raw materials are natural raw materials in specific production places and specific harvesting time, and the quality and purity are strictly guaranteed. The plaster is in an external application dosage form, and is uniform in texture, firm in application, small in irritation and long in shelf life. During use, after the skin of a painful part is cleaned up, 1 part of the plaster is smeared on sterile gauze and applied to the painful part once a day, seven days are taken as a course of treatment, and the number of courses of treatment is adjusted according to the degree of pains. The plaster can be used for effectively treating various pains such as muscular soreness, arthralgia, traumatic injury pains, rheumatic arthralgia and neuralgia, and is exact in treatment effect and safe and convenient to use.

Description

Technical Field

[0001] This invention relates to the field of external preparations of traditional Chinese medicine, specifically to a traditional Chinese medicine plaster for treating pain and its method of use. Background Technology

[0002] Pain is a common clinical symptom caused by various factors, such as muscle fatigue, joint disorders, sprains and strains, rheumatic pain, and neuropathy, significantly impacting patients' quality of life. Currently, there are many types of medications available for treating pain, including oral analgesics, topical patches, and injections. While oral analgesics have a rapid onset of action, long-term use may damage organs such as the gastrointestinal tract, liver, and kidneys, and carries a certain risk of addiction. Injectable medications are inconvenient to use and may cause adverse reactions such as injection site pain and infection.

[0003] Topical patches have attracted widespread attention due to their convenience, direct application to the affected area, and minimal systemic adverse reactions. However, existing topical herbal patches have diverse formulations, some with complex ingredients and excessive excipients or chemical additives, potentially increasing the risk of skin allergies. Inappropriate ingredient selection or improper proportions in some formulations lead to poor therapeutic effects. Furthermore, some patches suffer from problems such as poor adhesion, easy detachment, and significant irritation. Therefore, developing a simple, natural, effective, safe, and convenient herbal plaster for pain relief, along with its application method, is of significant practical importance. Summary of the Invention

[0004] In view of the problems of complex formulations, unnecessary ingredients, poor therapeutic effects, inadequate safety, and unsatisfactory application effects of existing topical pain treatment patches, this invention provides a traditional Chinese medicine plaster for pain treatment and its application method. It uses specific weight parts of natural Chinese herbal raw materials, without adding any other ingredients. The formula is scientific and reasonable, the therapeutic effect is definite, it is safe and convenient to use, it adheres firmly, and it has low irritation.

[0005] To achieve the above objectives, the present invention is implemented through the following technical solution: a traditional Chinese medicine plaster for treating pain and its method of use. The traditional Chinese medicine plaster for treating pain is composed of the following raw materials in parts by weight: 10 grams of raw aconite, 10 grams of raw pinellia, 10 grams of white mustard seed, 10 grams of evodia fruit, 10 grams of sulfur, and 5 grams of borneol, totaling 55 grams. The raw material composition of the plaster is a unique formula, without the addition of any other traditional Chinese medicine ingredients, chemical drug ingredients, or excipient ingredients. All the raw materials are natural raw materials, and the weight error of each raw material does not exceed ±0.5 grams, and the purity of each raw material is not less than 98%.

[0006] Furthermore, the plaster is a topical application form, in the form of a paste with a uniform texture and no obvious granular feel. The thickness of the paste is 0.5-1.0 cm, and the pH value of the plaster is 6.5-7.5. Under an environment of 25℃ and 60% relative humidity, the shelf life of the plaster is 12 months, and there are no signs of deterioration such as layering, mold, or odor during the shelf life. After application, it adheres tightly to the skin, is not easy to fall off, and has no obvious irritation.

[0007] Furthermore, strict limits were imposed on the origin, harvesting time, and properties of each raw material to ensure its quality and efficacy, as detailed below: Raw Aconitum carmichaelii: It is produced in Jiangyou, Sichuan Province, and is harvested from September to November each year. Its tuberous root is 2-5 cm in diameter, grayish-black or grayish-brown in color, with salt frost, and has a sunken bud scar at the top. There are nodular protruding lateral roots or lateral root scars around it. It has a firm texture, a horny cross-section, and is white or pale yellow. It has a slight odor and a pungent and numbing taste.

[0008] Raw Pinellia: It is produced in Xihe County, Gansu Province, and is harvested in August and September each year. The tuber is spherical, 1-2 cm in diameter, white or light yellow on the surface, with a sunken stem scar at the top and densely covered with dotted root scars around it. It is firm in texture, white in cross-section, rich in starch, has a slight odor, and tastes spicy, numbing and irritating to the throat.

[0009] White mustard seed: It is produced in Bozhou, Anhui Province, and is harvested in June and July each year. The seeds are spherical, 1.5-2.5 mm in diameter, grayish-white to pale yellow in color, with fine reticulations and obvious dotted hilum. The seed coat is thin and brittle, the endosperm is white and oily, with a slight odor and a spicy taste.

[0010] Evodia rutaecarpa: It is produced in Tongren, Guizhou Province, and is harvested in October and November each year. The fruit is spherical or slightly pentagonal flattened spherical, 2-5 mm in diameter. The surface is dark yellowish-green to brown, rough, with many dot-like protrusions or sunken oil dots. There is a five-pointed star-shaped crack at the top, and the base has a fruit stalk covered with yellow hairs. It is hard and brittle. The cross-section shows 5 locules of ovary, each containing 1 pale yellow seed. It has a strong aromatic odor and a spicy and bitter taste.

[0011] Sulfur: Originating in Yuncheng, Shanxi Province, it is naturally crystalline sulfur, in irregular lumps of varying sizes, with a yellow or brownish-yellow, glossy surface. It is brittle and easily broken, with a greasy luster on the cross-section. It is translucent, with a hardness of 1-2 and a specific gravity of 2.0-2.1. It has a faint odor and a bland taste.

[0012] Borneol: Originating in Guangzhou, Guangdong, it is a processed natural borneol product. It is in the form of translucent flakes, blocks or granules, with a diameter of 1-7 mm and a thickness of 0.5-1 mm. It is white or off-white with a glassy luster, loose and brittle texture, easy to break, fragrant aroma, spicy and cool taste, volatile, and produces thick smoke and a luminous flame when burned.

[0013] This invention also provides a method for using a traditional Chinese medicine plaster for treating pain. Before use, clean the patient's painful area with warm water, dry it, and ensure the skin is free of damage, inflammation, and allergies. Then, take one portion of the plaster (1 gram) and apply it evenly to sterile gauze. The application area should be adjusted according to the size of the painful area, generally 1.2-1.5 times the size of the painful area. Smoothly apply the gauze with the plaster to the painful area, securing the four corners with medical tape to ensure close contact between the plaster and the skin. The application time is 8-12 hours, once daily, for 7 days as one course of treatment. The number of courses can be adjusted according to the severity of the pain symptoms: 1-2 courses for mild pain, 2-3 courses for moderate pain, and 3-4 courses for severe pain.

[0014] Furthermore, during the application period, the application site should be kept dry and clean. Avoid getting the plaster wet, rained on, or swimming, which may cause it to fall off. Avoid strenuous exercise, which may cause the plaster to shift. If mild itching, redness, or other discomfort occurs at the application site, the application time can be reduced to 6-8 hours. If the discomfort worsens or allergic reactions such as rashes or blisters occur, the plaster should be removed immediately, the local skin should be washed with clean water, use should be discontinued, and medical attention should be sought promptly.

[0015] Furthermore, the pain includes muscle soreness, joint pain, sprains and strains, rheumatic pain, and neuralgia. Among them, muscle soreness is muscle fatigue soreness after exercise or muscle tension soreness caused by prolonged sitting or standing; joint pain is joint swelling and pain caused by osteoarthritis, rheumatoid arthritis, etc.; sprains and strains are local soft tissue pain caused by external impact, sprains, contusions, etc.; rheumatic pain is limb and joint pain, numbness, and difficulty in flexion and extension caused by wind, cold and dampness invading the body; and neuralgia is pain caused by peripheral nerve lesions such as trigeminal neuralgia and sciatica.

[0016] Furthermore, the plaster should be inspected before use to ensure that it is free from deterioration and odor, and that the plaster is uniform in consistency. If the plaster shows any abnormalities such as layering, mold, odor, or clumping, it should not be used. If the plaster falls off after application, it should be replaced with a new plaster and reapplied promptly. When replacing the plaster, the skin should be cleaned before reapplying to avoid residual plaster affecting the application effect.

[0017] Furthermore, this plaster is for external use only and should not be taken orally. It should not come into contact with the eyes, mouth, nose, or other mucous membranes. Pregnant women, breastfeeding women, children, and those with skin allergies should use it with caution. It should be used under the guidance of a physician. If the pain symptoms do not improve or worsen after one course of treatment, you should go to the hospital in time to adjust the treatment plan. The plaster should be stored in a sealed container in a cool, dry place, avoiding direct sunlight, high temperature and humidity. The storage temperature should be 5-25℃ and the relative humidity should not exceed 60%.

[0018] This invention provides a traditional Chinese medicine plaster for treating pain and its method of use, which has the following beneficial effects: The herbal plaster for treating pain of this invention uses specific weight proportions of natural Chinese herbal raw materials. The formula is simple and pure, without adding any other irrelevant ingredients, thus avoiding the risk of allergies and interference with efficacy caused by complex ingredients. Each raw material is selected from high-quality natural raw materials from specific producing areas and harvesting times, and the properties and purity of the raw materials are strictly limited to ensure the quality and efficacy stability of the raw materials. The plaster dosage form is reasonably designed, with a uniform texture, firm application, low irritation, and long shelf life. The method of use is simple and convenient, and clear usage plans have been formulated for different types of pain and different degrees of pain symptoms. The treatment effect is definite, which can effectively relieve various pain symptoms, improve the quality of life of patients, and is safe and reliable to use with no obvious systemic adverse reactions, and has broad application prospects. Detailed Implementation

[0019] How to use: Preparation before use: Before use, check the condition of the plaster to ensure that the plaster is uniform, without layering, mold, odor, lumps or other abnormalities. If any of the above abnormalities are present, do not use it. At the same time, confirm that the skin at the painful site is not broken, inflamed or ulcerated, and that the user has no history of allergies to the plaster's ingredients. Pregnant women, breastfeeding women, children, and people with skin allergies should use it under the guidance of a physician and avoid blind application.

[0020] Skin cleansing: Wash the painful area with warm water at 30-40℃. Avoid using irritating cleansing products such as soap and shower gel. Gently rub to remove dirt, oil and sweat from the skin surface. Then gently pat the skin dry with a clean, soft towel to ensure that the skin is dry, clean and free of moisture.

[0021] Application and application of the plaster: Take one portion (1 gram) of plaster each time according to the severity and size of the pain symptoms. Apply it evenly to a sterile gauze, keeping the thickness consistent, about 0.5-1.0 cm. The application area should be 1.2-1.5 times the actual area of ​​the pain, ensuring complete coverage of the painful area and the surrounding 1-2 cm. Avoid uneven application, which may lead to insufficient local efficacy or excessive irritation.

[0022] Application procedure: Apply the sterile gauze with the ointment to the treated painful area. Gently press the edges and center of the gauze with your fingers to expel air between the gauze and the skin, ensuring the ointment adheres tightly to the skin. Then, use medical breathable tape to secure the four corners and edges of the gauze to prevent the ointment from shifting or falling off due to movement after application.

[0023] Application duration and frequency: The application time for a single application is 8-12 hours. It is recommended to apply the patch at night while sleeping to reduce the impact of activities on the application effect. Apply the patch once a day for 7 consecutive days as one course of treatment. Do not interrupt the application at will.

[0024] Treatment course adjustment: For patients with mild pain (pain score of 3 or below, visual analog scale), use 1-2 courses of treatment. Use can be stopped after the pain symptoms are completely relieved. For patients with moderate pain (pain score of 4-6), use 2-3 courses of treatment. During this period, the pain relief should be observed. If the symptoms do not improve significantly after 2 courses of treatment, consult a doctor to adjust the usage method. For patients with severe pain (pain score of 7 or above), use 3-4 courses of treatment. The efficacy should be evaluated after each course of treatment, and the subsequent usage plan should be adjusted according to the changes in symptoms.

[0025] Care during application: Keep the application area dry and clean during the application period. Avoid getting it wet, rained on, or swimming, which may cause the plaster to become wet and fall off. Avoid strenuous exercise or heavy physical labor to prevent the gauze from shifting. Do not tear or press the application area to avoid the plaster falling off or damaging the skin.

[0026] Management of discomfort: If mild itching or redness occurs at the application site without other abnormalities, the application time can be reduced to 6-8 hours per application, and the symptoms should be observed. If the itching or redness worsens, or if allergic reactions such as rash, blisters, or stinging occur, the gauze should be removed immediately, the local skin should be gently cleaned with water to remove any residual ointment, the use of the ointment should be discontinued, and medical consultation should be sought promptly. If any other physical discomfort occurs during use, use should also be discontinued and medical attention sought.

[0027] Contraindications and precautions: This ointment is for external use only and must not be taken orally. Avoid contact with eyes, mouth, nose, or other mucous membranes. If other topical medications are used simultaneously, allow at least 4 hours between applications, or consult a physician before use. If pain symptoms do not improve or even worsen after one course of treatment, seek medical attention promptly to change the treatment plan.

[0028] Storage and usage guidelines: Unused plasters should be sealed and stored in a cool, dry place at a temperature of 5-25℃ and a relative humidity of no more than 60%. Avoid direct sunlight and high temperature and humidity environments to prevent the plaster from deteriorating. When taking out plasters, use sterile tools and avoid direct contact with the plaster with your hands to prevent contamination of the plaster and affect its effectiveness and safety.

[0029] Example: Example 1: Preparation of a traditional Chinese medicine plaster for treating pain The raw materials are weighed according to the following proportions: 10g of raw aconite root, 10g of raw pinellia tuber, 10g of white mustard seed, 10g of evodia fruit, 10g of sulfur, and 5g of borneol. The weight error of each raw material is controlled within ±0.5g, and the purity of each raw material is not less than 98%. Among them, the raw aconite root is produced in Jiangyou, Sichuan, and the harvest time is October; the raw pinellia tuber is produced in Xihe, Gansu, and the harvest time is August; the white mustard seed is produced in Bozhou, Anhui, and the harvest time is June; the evodia fruit is produced in Tongren, Guizhou, and the harvest time is October; the sulfur is produced in Yuncheng, Shanxi; and the borneol is produced in Guangzhou, Guangdong.

[0030] The raw aconite, raw pinellia, white mustard seed, evodia fruit, and sulfur are pulverized into 100-120 mesh powder. Then, the powders are mixed evenly, and an appropriate amount of natural plant oil (used only as a base, without adding other ingredients) is added. The mixture is stirred evenly and heated to 60-80℃. The mixture is kept warm and stirred for 30-40 minutes to fully integrate the ingredients. Then, borneol powder is added, and the mixture is stirred for another 15-20 minutes. After cooling to room temperature, a paste-like traditional Chinese medicine plaster for treating pain is obtained. The thickness of the plaster is controlled at 0.5-1.0 cm, and the pH value is 6.5-7.5.

[0031] Example 2: Use of a traditional Chinese medicine plaster for treating pain One hundred patients with pain were selected, including 20 patients with muscle soreness, 20 patients with joint pain, 20 patients with sprains and strains, 20 patients with rheumatic pain, and 20 patients with neuralgia. Among the patients of each type, mild, moderate, and severe pain accounted for a certain proportion.

[0032] The herbal plaster prepared in Example 1 was used as follows: First, the patient's painful area was cleaned with warm water and dried to ensure that the skin was free of damage, inflammation, and allergies. Then, one portion of the plaster (1 gram) was taken and evenly applied to sterile gauze, covering an area 1.2-1.5 times the size of the painful area. The gauze with the plaster was then applied smoothly to the painful area, and the four corners of the gauze were secured with medical tape to ensure close contact between the plaster and the skin. The application time was 8-12 hours, once a day, for 7 days as one course of treatment.

[0033] Patients with mild pain should use 1-2 courses of treatment, those with moderate pain should use 2-3 courses, and those with severe pain should use 3-4 courses. Keep the application site dry and clean during the treatment period, and avoid contact with water and strenuous exercise.

[0034] Treatment results showed that more than 90% of patients experienced significant relief from pain symptoms. The cure rate for mild pain was 95%, the cure rate for moderate pain was 85%, and the effective rate for severe pain was 80%. No serious allergic reactions or other adverse reactions were observed in any patient during use. Only a few patients experienced mild skin itching, which was relieved by reducing the application time.

[0035] Although embodiments of the invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A traditional Chinese medicine composition plaster for treating pain and a method of using the same, characterized in that: This plaster is composed of the following ingredients in parts by weight: 10g raw aconite, 10g raw pinellia, 10g white mustard, 10g evodia, 10g sulfur, and 5g borneol, totaling 55g. This plaster has a unique formula and does not contain any other traditional Chinese medicine ingredients, chemical drug ingredients, or excipients. All ingredients are natural. Raw aconite is the unprocessed raw aconite root; raw pinellia is the unprocessed raw pinellia; white mustard is the dried mature seed of white mustard (a plant in the Brassicaceae family); evodia is the dried nearly mature fruit of evodia, schizonepeta, or sparsely hairy evodia (all plants in the Rutaceae family); sulfur is natural sulfur (a natural element mineral); and borneol is a processed resin or chemically synthesized product of borneol (a plant in the Dipterocarpaceae family). The weight error of each ingredient does not exceed ±0.5g, and the purity of each ingredient is not less than 98%. ​ 2. The herbal plaster for treating pain according to claim 1 and its method of use, characterized in that: The plaster is a topical application form, in the form of a paste with a uniform texture and no obvious granular feel. The thickness of the paste is 0.5-1.0 cm, and the pH value of the plaster is 6.5-7.

5. Under an environment of 25℃ and 60% relative humidity, the shelf life of the plaster is 12 months, and there are no signs of deterioration such as layering, mold, or odor during the shelf life. After application, it adheres tightly to the skin, is not easy to fall off, and has no obvious irritation.

3. The herbal plaster for treating pain according to claim 1 and its method of use, characterized in that: The raw aconite root is produced in Jiangyou, Sichuan, and is harvested from September to November each year. Its tuber diameter is 2-5 cm, the surface is grayish-black or grayish-brown, with salt frost, the top has a sunken bud scar, and there are nodular protruding lateral roots or lateral root scars around it. It is firm in texture, the cross-section is horny, white or light yellow, has a slight odor, and tastes spicy and numbing to the tongue. The raw pinellia tuber is produced in Xihe, Gansu, and is harvested from August to September each year. The tuber is spherical, 1-2 cm in diameter, the surface is white or light yellow, the top has a sunken stem scar, and there are densely dotted root scars around it. It is firm in texture, the cross-section is white, rich in starch, has a slight odor, and tastes spicy, numbing to the tongue and irritating to the throat.

4. The herbal plaster for treating pain according to claim 1 and its method of use, characterized in that: The white mustard seed is produced in Bozhou, Anhui Province, and is harvested in June and July each year. The seeds are spherical, 1.5-2.5 mm in diameter, with a grayish-white to pale yellow surface, fine reticulations, and obvious dotted hilum. The seed coat is thin and brittle, the endosperm is white, oily, has a slight odor, and a pungent taste. The Evodia rutaecarpa is produced in Tongren, Guizhou Province, and is harvested in October and November each year. The fruit is spherical or slightly pentagonal flattened spherical, 2-5 mm in diameter, with a dark yellowish-green to brown, rough surface, with numerous dotted protrusions or sunken oil dots, a pentagonal star-shaped fissure at the top, and a fruit stalk covered with yellow hairs remaining at the base. It is hard and brittle, and the cross-section shows a 5-locular ovary, with one pale yellow seed in each locule. It has a strong aromatic odor and a pungent and bitter taste.

5. A traditional Chinese medicine plaster for treating pain according to claim 1 and its method of use, characterized in that: The sulfur is from Yuncheng, Shanxi Province. It is a naturally crystalline sulfur, in irregular lumps of varying sizes, with a yellow or brownish-yellow, glossy surface. It is brittle and easily broken, with a greasy luster on the cross-section. It is translucent, with a hardness of 1-2 and a specific gravity of 2.0-2.

1. It has a faint odor and a bland taste. The borneol is from Guangzhou, Guangdong Province. It is a processed natural borneol product, in translucent flakes, lumps, or granules, with a diameter of 1-7 mm and a thickness of 0.5-1 mm. It is white or off-white, with a glassy luster. It is loose and brittle, easily broken, with a fragrant aroma and a pungent, cool taste. It is volatile and produces thick smoke and a luminous flame when ignited.

6. A traditional Chinese medicine plaster for treating pain according to any one of claims 1-5 and its method of use, characterized in that: Before use, clean the patient's painful area with warm water and dry it, ensuring the skin is free of damage, inflammation, and allergies. Then, take one portion (1 gram) of the above-mentioned herbal plaster and apply it evenly to a sterile gauze. The application area should be adjusted according to the size of the painful area, generally 1.2-1.5 times the size of the painful area. Smoothly apply the gauze with the plaster to the painful area and secure the four corners of the gauze with medical tape to ensure close contact between the plaster and the skin. The application time is 8-12 hours, once a day, for 7 days as one course of treatment. The number of courses of treatment can be adjusted according to the severity of the pain symptoms. Patients with mild pain need 1-2 courses of treatment, patients with moderate pain need 2-3 courses of treatment, and patients with severe pain need 3-4 courses of treatment.

7. A traditional Chinese medicine plaster for treating pain according to claim 6 and its method of use, characterized in that: During application, keep the application area dry and clean. Avoid getting the plaster wet, rained on, or swimming, as this may cause it to fall off. Avoid strenuous exercise, which may cause the plaster to shift. If mild itching, redness, or other discomfort occurs at the application site, reduce the application time to 6-8 hours. If the discomfort worsens or allergic reactions such as rashes or blisters occur, remove the plaster immediately, wash the affected area with clean water, discontinue use, and seek medical attention promptly.

8. A traditional Chinese medicine plaster for treating pain according to claim 6 and its method of use, characterized in that: The pain includes muscle soreness, joint pain, sprains and strains, rheumatic pain, and neuralgia. Among them, muscle soreness is muscle fatigue soreness after exercise or muscle tension soreness caused by prolonged sitting or standing; joint pain is joint swelling and pain caused by osteoarthritis, rheumatoid arthritis, etc.; sprains and strains are local soft tissue pain caused by external impact, sprains, contusions, etc.; rheumatic pain is limb and joint pain, numbness, and difficulty in flexion and extension caused by wind, cold and dampness invading the body; and neuralgia is pain caused by peripheral nerve lesions such as trigeminal neuralgia and sciatica.

9. A traditional Chinese medicine plaster for treating pain according to claim 6 and its method of use, characterized in that: Before use, the plaster should be inspected to ensure that it is free from deterioration and odor, and that the plaster is uniform in consistency. If the plaster shows any abnormalities such as layering, mold, odor, or clumping, it should not be used. If the plaster falls off after application, it should be replaced with a new plaster immediately. When replacing the plaster, the skin should be cleaned before reapplying to avoid residual plaster affecting the application effect.

10. A traditional Chinese medicine plaster for treating pain according to claim 6 and its method of use, characterized in that: This plaster is for external use only and should not be taken orally. Avoid contact with eyes, mouth, nose, or other mucous membranes. Pregnant women, breastfeeding women, children, and those with skin allergies should use with caution. Use under the guidance of a physician. If pain symptoms do not improve or worsen after one course of treatment, consult a doctor promptly to adjust the treatment plan. The plaster should be stored in a sealed container in a cool, dry place, away from direct sunlight, high temperature, and humidity. The storage temperature should be 5-25℃, and the relative humidity should not exceed 60%.