Natural Chinese herbal medicine hair-nourishing composition and preparation process thereof

Abstract

The invention discloses a natural Chinese herbal medicine hair nourishing composition and a preparation process thereof, and relates to the technical field of hair nourishing and caring, the composition comprises 8-12 parts of a targeted inhibition core Chinese herbal medicine group, 2-3 parts of a scalp conditioning and synergistic group, and 85-90 parts of a pharmaceutic adjuvant adaptation system; the targeted inhibition core Chinese herbal medicine group consists of the following components: 1.5-2 parts of a green tea polyphenol extract, 0.8-1 part of a rosemary supercritical CO2 extract, 0.5-1 part of a poria cocos triterpene purified product, 2-3 parts of a cacumen biotae ethanol extract, 1-1.5 parts of a glossy privet fruit ethanol extract, 0.8-1 part of a mulberry leaf extract and 0.8-1 part of a polygonum multiflorum ethanol extract; a function complementary hair nourishing formula system is constructed, all the components are reasonably matched, the activity of the raw materials is reserved after treatment, and a mild and effective foundation is laid for external hair nourishing; meanwhile, the preparation process is standardized, the quality control is strict, the product quality and safety are guaranteed in multiple links from preparation to storage, effective component retention, practicability and safety are considered, and the safe and effective hair nourishing requirements of users are met.

Description

Technical Field

[0001] This invention relates to the field of hair care technology, specifically to a natural Chinese herbal hair care composition and its preparation process. Background Technology

[0002] With the fast pace of life, changing environmental factors, and the impact of unhealthy lifestyle habits, scalp health problems are becoming increasingly prominent, making hair care a significant public concern. Traditional Chinese medicine has a long history of application in hair care, and its natural and gentle properties align with modern consumers' pursuit of safe hair care products. Compared to chemically synthesized ingredients, traditional Chinese medicine ingredients are more easily absorbed by the scalp and can regulate the scalp environment from the root. Therefore, natural traditional Chinese herbal hair care products have gradually become a hot topic in industry research and development and market consumption. External application of hair care products allows the effective ingredients to act directly on the scalp and hair roots, quickly exerting a conditioning effect, and has become the mainstream form of hair care products. The optimization and upgrading of related technologies are of great significance for improving hair care effects and ensuring safety of use, and also provide a broad technological space and market foundation for the research and development of natural traditional Chinese herbal hair care compositions.

[0003] Traditional Chinese herbal hair care products lack a scientific and systematic approach to formulation design. The combination of ingredients often relies on experience, failing to form a synergistic system of complementary functions. This results in insufficient utilization of the effective ingredients. In terms of extraction processes, the techniques are relatively simple, making it difficult to accurately preserve the active ingredients in Chinese herbs. Some processes may even damage the structure of the effective ingredients, affecting product efficacy. The lack of strict aseptic control and quality management standards during the preparation process makes it prone to problems such as excessive microorganisms and impurities, posing potential risks to users. At the same time, traditional products have poor scalp adaptability, and some products may irritate the scalp. Furthermore, the products lack stability and are prone to degradation and morphological changes of effective ingredients during storage. The convenience of use also fails to meet the needs of modern consumers, making it difficult to balance gentleness, effectiveness, and safety. Summary of the Invention

[0004] The purpose of this invention is to overcome the shortcomings of existing technologies and provide a natural herbal hair care composition and its preparation process. The core formula consists of a targeted inhibitory core herbal group, a scalp conditioning and synergistic group, and a pharmaceutical excipient adaptation system. It selects high-quality herbal raw materials from authentic producing areas and uses specialized extraction and purification techniques to retain the activity of effective components. The preparation process follows aseptic control, precise mixing, standardized drying and pulverization, and strict quality testing procedures to ensure that the product's physicochemical indicators, microbial limits, and safety meet standards. The product is in powder form, can be dissolved in water for external application, and combines gentleness and effectiveness. It can synergistically condition the scalp environment and meet hair care needs. This invention overcomes the shortcomings of traditional hair care products, such as unscientific formulations and non-standard processes, achieving a balance between the utilization of natural ingredients, product quality, and ease of use. It provides consumers with a safe and effective natural hair care option and promotes the standardized development of herbal hair care technology.

[0005] To solve the above-mentioned technical problems, the present invention provides the following technical solution: On one hand, a natural Chinese herbal hair-nourishing composition, by weight, comprising: 8-12 parts of a core Chinese herbal medicine group targeting inhibition, 2-3 parts of a scalp conditioning and synergistic group, and 85-90 parts of a pharmaceutical excipient adaptation system; the core Chinese herbal medicine group targeting inhibition is composed of the following components: 1.5-2 parts of green tea polyphenol extract, 0.8-1 parts of rosemary supercritical CO2 extract, 0.5-1 parts of purified poria triterpenoids, 2-3 parts of arborvitae leaf ethanol extract, 1-1.5 parts of privet fruit ethanol extract, and mulberry... The composition comprises: 0.8-1 parts leaf extract and 0.8-1 parts Polygonum multiflorum alcohol extract; the scalp conditioning and synergistic group consists of: 0.4-0.5 parts dipotassium glycyrrhizate, 0.1-0.2 parts menthol, 0.5-0.8 parts Sophora flavescens extract, and 0.8-1 parts Ligusticum chuanxiong extract; the pharmaceutical excipient formulation system consists of: 60-70 parts maltodextrin, 15-20 parts lactose, and 0.3-0.5 parts sodium dehydroacetate / potassium sorbate compound preservative; the total weight of all components is 100 parts. The composition is in powder form and is used for external hair care after dissolving in water.

[0006] Furthermore, the specifications of each component in the core Chinese herbal medicine group targeting inhibition are as follows: EGCG content of green tea polyphenol extract ≥90%, rosmarinic acid content of rosemary supercritical CO2 extract ≥20%, total triterpenoid content of Poria triterpenoid purified extract ≥80%, solid content of Platycladus orientalis leaf ethanol extract approximately 50%, solid content of Ligustrum lucidum ethanol extract approximately 45%, total flavonoid content of mulberry leaf extract ≥15%, and emodin content of Polygonum multiflorum ethanol extract 1.2%-1.5% and chrysophanol content ≤0.8%.

[0007] Furthermore, in the scalp conditioning and synergistic group, the total content of matrine and oxymatrine in the Sophora flavescens extract is ≥4.0%, and the content of ferulic acid in the Ligusticum chuanxiong extract is ≥1.0%; in the pharmaceutical excipient adaptation system, the mass ratio of sodium dehydroacetate / potassium sorbate compound preservative is 1:1, the DE value of maltodextrin is 10-20, and the purity of lactose is ≥99%.

[0008] Furthermore, the physicochemical properties of the composition are as follows: particle size ≤100μm, moisture content ≤5.0%, pH value after dissolution 5.5-6.0; microbial limits: total bacterial count ≤100CFU / g, total mold and yeast count ≤10CFU / g, pathogenic bacteria not detectable; total heavy metal content ≤10ppm.

[0009] On the other hand, a method for preparing a natural Chinese herbal hair-nourishing composition, the specific steps of which are as follows: S1, Targeted preparation and purification of extracts: Select traditional Chinese medicinal materials from authentic producing areas, remove impurities and crush them, and prepare each traditional Chinese medicinal material extract using corresponding extraction and purification techniques. After passing the test, weigh them for later use. S2, Raw material mixing and dispersion: In a sterile mixing tank, maltodextrin and lactose from the pharmaceutical excipient adaptation system are added in sequence, followed by the extracts of the core Chinese herbal medicine group for targeted inhibition and the components of the scalp conditioning and synergistic group. Stirring is started and the mixture is mixed evenly. Then, an appropriate amount of deionized water is slowly added and stirred to form a uniform suspension. S3, Drying and Shaping: The suspension obtained in step S2 is dried by spray drying or freeze drying to remove moisture and obtain solid particles; S4, Grinding and sieving: Transfer the solid particles obtained in step S3 into a sterile grinding device for grinding. After grinding, pass them through an 80-100 mesh standard sieve and collect the powder that passes through the sieve. S5, Post-processing and warehousing: The sieved powder is sterilized, and the particle size, moisture content and microbial limits are tested. After passing the sampling inspection, it is sealed and packaged in a clean environment and stored in the warehouse.

[0010] Furthermore, the particle size of the pulverized Chinese herbal raw materials is controlled as follows: rosemary leaves, tender branches and leaves of arborvitae, and dried roots of sophora flavescens ≤450μm, processed Polygonum multiflorum slices ≤300μm, and dried rhizome of Ligusticum chuanxiong ≤250μm; the microbial limits of each extract are: total bacterial count ≤100CFU / g, total mold and yeast count ≤10CFU / g, and pathogenic bacteria not detectable. After passing the test, the extracts are stored at 4-8℃ for storage for ≤72 hours.

[0011] Furthermore, the corresponding extraction and purification technique is as follows: Supercritical CO2 extract of rosemary: Dried rosemary leaves were pulverized and passed through a 40-mesh sieve, then fed into a supercritical CO2 extraction vessel. 95% ethanol (15% by weight of the raw material) was added as an entrainer. The extraction pressure was 28 MPa ± 0.5 MPa, the temperature was 45℃ ± 1℃, and the CO2 flow rate was 25 kg / h ± 2 kg / h. Dynamic extraction was performed for 2.5 hours ± 5 minutes. The separation vessel was then set at a pressure of 6 MPa ± 0.3 MPa and a temperature of 35℃ ± 1℃, and the extract was collected. Purified Poria triterpenoids: After pulverizing Poria cocos slices, add 8 times the amount of 75% ethanol solution and extract three times under ultrasonic assistance at 50℃±2℃ and 300W±20W for 30 minutes±2 minutes each time. Combine the extracts and recover the ethanol under reduced pressure to obtain a concentrated extract. Disperse the extract with deionized water and load it onto an AB-8 macroporous adsorption resin column. First, elute with 5 column volumes of deionized water at a flow rate of 2 BV / h to remove impurities, and then elute with a gradient of 6 column volumes of 85% ethanol at a flow rate of 1.5 BV / h. Collect the eluent, concentrate under reduced pressure, and spray dry. Green tea polyphenol extract: Green tea powder was extracted with deionized water at 80℃±2℃ using countercurrent circulation. After impurities were removed by a tubular centrifuge, the extract was transferred to a low-temperature membrane separation system at ≤10℃. It was concentrated by an ultrafiltration membrane with a molecular weight cutoff of 1000Da±50Da, and then further concentrated by a nanofiltration membrane with a molecular weight cutoff of 200Da±20Da. Nitrogen protection was maintained throughout the process. Ethanol extract of Platycladus orientalis leaves: The dried tender branches and leaves of Platycladus orientalis were pulverized and passed through a 40-mesh sieve. Eight times the amount of 70% ethanol was added, and the mixture was refluxed twice at 80℃±2℃ for 1.5 hours±5 minutes each time. The extracts were combined and concentrated under reduced pressure to a relative density of 1.20-1.25 (60℃). Ligustrum lucidum ethanol extract: After pulverizing dried and mature privet fruit, add 10 times the amount of 60% ethanol, and extract three times with ultrasonic assistance at 50℃±2℃ and 400W, each time for 40 minutes±3 minutes. After filtering the extract, recover the ethanol under reduced pressure and concentrate to a solid content of 45%. Mulberry leaf extract: After drying and pulverizing mulberry leaves, add 12 times the amount of deionized water and reflux at 90℃±2℃ for 2 hours±5 minutes. After cooling the extract, add 95% ethanol to the system ethanol concentration of 70%±1% and let stand for 24 hours±1 hour for alcohol precipitation. Remove the supernatant by siphon, filter the lower precipitate and concentrate under reduced pressure. Polygonum multiflorum alcohol extract: Processed Polygonum multiflorum slices were pulverized and passed through a 50-mesh sieve. Nine times the amount of 75% ethanol was added, and the mixture was refluxed at 85℃±2℃ twice, each time for 2 hours±5 minutes. The extracts were combined and concentrated under reduced pressure. Sophora flavescens extract: The dried root of Sophora flavescens was pulverized and passed through a 40-mesh sieve. 10 times the amount of 65% ethanol was added, and the extract was extracted three times at 55℃±2℃ and 350W ultrasonic assisted extraction for 35 minutes±3 minutes each time. The extract was centrifuged, filtered, and concentrated under reduced pressure. Ligusticum chuanxiong extract: The dried rhizome of Ligusticum chuanxiong was pulverized and passed through a 60-mesh sieve. Eight times the amount of 70% ethanol was added, and the extract was refluxed twice at 80℃±2℃ for 2 hours±5 minutes each time. The combined extracts were loaded onto an AB-8 macroporous adsorption resin column. First, impurities were removed by elution with 5 column volumes of deionized water at a flow rate of 2 BV / h. Then, a gradient elution was performed with 6 column volumes of 70% ethanol at a flow rate of 1.5 BV / h. The eluent was collected and concentrated under reduced pressure.

[0012] Furthermore, in step S2, during the stirring and mixing: the initial mixing speed is 500 rpm ± 50 rpm, and the mixing time is 15 minutes ± 2 minutes; after adding deionized water, the stirring speed of the suspension is 800 rpm ± 100 rpm, and the stirring time is 20 minutes ± 3 minutes; the solid content of the suspension is controlled to be 30%-40%, the conductivity of the deionized water is ≤5 μS / cm, and the total heavy metal content is ≤1 ppm.

[0013] Furthermore, the spray drying process specifically includes: inlet air temperature 160℃±5℃, outlet air temperature 70℃±3℃, atomization pressure 0.3MPa±0.05MPa, and feed rate 50mL / min±5mL / min; the freeze drying process specifically includes: pre-freezing temperature -40℃±5℃, pre-freezing time 4 hours±0.5 hours, sublimation drying temperature -10℃±2℃, desorption drying temperature 30℃±2℃, vacuum degree 0.01MPa±0.002MPa, and total drying time 24 hours±2 hours.

[0014] Furthermore, the pulverizing speed is 10000rpm±1000rpm, the pulverizing time is 5 minutes±1 minute, the sieve mesh size is 90 mesh±10 mesh, and the particle size of the powder passing through the sieve is ≤100μm; the sterilization treatment is carried out by gamma irradiation with an irradiation dose of 5kGy-8kGy; the packaging container is a sterilized aluminum foil sealed bag, the storage environment temperature is 15-25℃, the relative humidity is ≤65%, and the shelf life is ≤24 months.

[0015] Compared with existing technologies, this natural Chinese herbal hair care composition and its preparation process have the following beneficial effects: I. This invention constructs a complementary hair care formula system by rationally combining a core Chinese herbal medicine group for targeted inhibition, a scalp conditioning and enhancement group, and a pharmaceutical excipient adaptation system. The core Chinese herbal medicine group for targeted inhibition integrates multiple Chinese herbal extracts to exert targeted hair care effects. The scalp conditioning and enhancement group assists in regulating the scalp microenvironment and enhances overall efficacy. The pharmaceutical excipient adaptation system provides a stable carrier for the active ingredients, ensuring that each component works synergistically. The raw materials are selected from authentic producing areas of Chinese herbs, which undergo strict impurity removal, pulverization, and specialized extraction and purification techniques to retain the activity of the active ingredients to the greatest extent. The combination of each component takes into account both targeted effects and scalp adaptability, avoiding irritation, and laying a gentle and effective ingredient foundation for external hair care. At the same time, it is suitable for external dissolution application, allowing the active ingredients to act more smoothly on the scalp, meeting the dual needs of scalp health care and hair care.

[0016] II. This invention ensures product quality and safety through standardized preparation processes and strict quality control. Starting with the targeted preparation and purification of extracts, the entire process is carried out in a sterile environment, including raw material mixing and dispersion, drying and shaping, pulverizing and sieving. Appropriate drying and pulverizing processes are used to ensure uniform product form, facilitating subsequent dissolution and use. Simultaneously, multi-stage sterilization treatment and comprehensive indicator testing cover multiple dimensions such as microorganisms, heavy metals, and physicochemical properties, strictly controlling product quality and avoiding harmful impurities. Environmental control during storage further maintains the stability of the product within its shelf life, ensuring that the active ingredients can function stably during use. The entire preparation process balances the preservation of active ingredients, product usability, and safety, giving the product reliable quality assurance and convenient usage to achieve synergistic effects of scalp conditioning and hair care, meeting users' needs for safe and effective hair care products.

[0017] Other advantages, objectives and features of the invention will be set forth in part in the description which follows, and in part will be apparent to those skilled in the art from the following examination or study, or may be learned from the practice of the invention. Attached Figure Description

[0018] To more clearly illustrate the technical solutions in the embodiments of the present invention or the prior art, the accompanying drawings used in the description of the embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are merely some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without any creative effort.

[0019] Figure 1 This is a flowchart illustrating the preparation method of a natural Chinese herbal hair care composition. Detailed Implementation

[0020] To further illustrate the technical means and effects of the present invention in achieving its intended purpose, the following detailed description of the specific implementation methods, structures, features, and effects of the present invention, in conjunction with the accompanying drawings and preferred embodiments, is provided below.

[0021] Example 1: The specific steps for preparing the natural Chinese herbal hair-nourishing powder composition are as follows: Figure 1 As shown.

[0022] Raw material preparation and pretreatment: We strictly select traditional Chinese medicinal herbs from their authentic producing areas. All raw materials are manually sorted to remove impurities, moldy parts, and non-medicinal components, and then pulverized using a WFJ-15 micro pulverizer. The pulverized raw materials are then packed into aluminum foil composite bags, sealed, and stored in a dry and ventilated raw material warehouse. The warehouse temperature is controlled between 15 and 25°C, and the relative humidity is ≤65% to prevent the raw materials from absorbing moisture and deteriorating.

[0023] Targeted preparation and purification of extracts: Green tea polyphenol extract: Take 10 kg of pulverized green tea powder and put it into a 50 L countercurrent extraction tank. Add 30 L of deionized water at 80℃±5℃, turn on the stirrer, set the stirring speed to 300 rpm, and extract countercurrently for 2 hours. After extraction, transfer the extract to a GF105 tubular centrifuge and centrifuge at 8000 rpm for 15 minutes to remove impurities. Collect the supernatant. Transfer the supernatant to a low-temperature membrane separation system, with the system temperature controlled at ≤10℃. First, pass it through an ultrafiltration membrane with a molecular weight cutoff of 1000 Da and concentrate it to one-fifth of its original volume under a pressure of 0.3 MPa. Then, pass it through a nanofiltration membrane with a molecular weight cutoff of 200 Da and further concentrate it to a relative density of 1.18 under a pressure of 0.5 MPa. Nitrogen protection is maintained throughout the concentration process to prevent oxidation of the active ingredients. The concentrated extract was transferred to an LGJ-10 vacuum freeze dryer and freeze-dried at -50℃ and 0.01MPa for 24 hours to obtain 1.2 kg of green tea polyphenol extract powder. High-performance liquid chromatography (HPLC) analysis showed an EGCG content of 92.5%. Microbiological testing showed a total bacterial count of 85 CFU / g, a total mold and yeast count of 6 CFU / g, and no detectable pathogens. The powder was packaged into sterile sealed bottles and refrigerated at 4℃ for later use.

[0024] Supercritical CO2 Extract of Rosemary: 5 kg of dried rosemary leaves were pulverized using a universal grinder and passed through a 40-mesh standard sieve. The pulverized leaves were then added to a 10 L supercritical CO2 extraction vessel. 750 mL of 95% ethanol (15% of the raw material weight) was added as an entrainer. The extraction vessel was closed, and the extraction pressure was set to 28 MPa ± 0.5 MPa, the extraction temperature to 45℃ ± 1℃, and the CO2 flow rate to 25 kg / h. Dynamic extraction was performed for 2 hours and 30 minutes. After extraction, the pressure in the separation vessel was adjusted to 6 MPa ± 0.3 MPa, and the temperature to 35℃ ± 1℃. The separated extract was collected, yielding 320 g of a pale yellow oily extract. The rosmarinic acid content was found to be 23.1%, and the microbial indicators met the standards. The extract was then packaged into a brown sterile bottle and refrigerated at 4℃ for later use.

[0025] Purified Poria cocos triterpenoids: Take 8 kg of Poria cocos slices, pulverize them, and put them into a 50 L ultrasonic extraction vessel. Add 64 L of 75% ethanol solution (8 times the volume of the extract). Set the extraction temperature to 50℃±2℃ and the ultrasonic power to 300W±20W. Extract three times, each time for 30 minutes. After each extraction, let stand for 10 minutes and collect the supernatant. Combine the three extracts and transfer them to a vacuum concentration vessel. Recover the ethanol under reduced pressure at 60℃-0.08 MPa to obtain 1.2 kg of concentrated extract. Disperse the extract with 5 L of deionized water. Load the dispersion onto an AB-8 macroporous adsorption resin column pre-equilibrated with 75% ethanol and activated with deionized water. First, elute with 5 column volumes of deionized water at a flow rate of 2 BV per hour to remove impurities, then elute with a gradient of 6 column volumes of 85% ethanol at a flow rate of 1.5 BV per hour. The eluent was collected and concentrated in a vacuum concentrator until it reached a thick paste state. It was then dried using an LPG-5 spray dryer to obtain 180 grams of purified Poria cocos triterpenoid powder. Testing showed that the total triterpenoid content was 83.7%. After meeting the microbial standards, it was refrigerated at 4°C for later use.

[0026] Ethanol extract of Platycladus orientalis leaves: Take 6 kg of dried young branches and leaves of Platycladus orientalis, pulverize them, pass them through a 40-mesh sieve, and put them into a 50 L reflux extraction tank. Add 48 L of 70% ethanol solution (8 times the volume of the extract). Set the extraction temperature to 80℃±2℃, and reflux extract twice, each time for 1 hour and 30 minutes, stirring once every 20 minutes during the extraction. Combine the two extracts and transfer them to a vacuum concentration tank. Concentrate to a relative density of 1.23 under the conditions of 65℃-0.09 MPa, yielding 850 g of brown extract. The solid content was tested and found to be 50.3%. After the microbial content met the standards, store at 4℃ for later use.

[0027] Ethanol extract of Ligustrum lucidum: Take 4 kg of dried, mature Ligustrum lucidum fruit, crush it, and put it into a 50 L ultrasonic extraction tank. Add 40 L of 60% ethanol solution (10 times the volume of the extract). Set the extraction temperature to 50℃±2℃ and the ultrasonic power to 400W. Extract three times, 40 minutes each time. After filtering the extract through a plate and frame filter, transfer it to a vacuum concentration tank to recover the ethanol. Concentrate to a solid content of 45%, obtaining 1.2 L of brownish-red concentrated solution. After the microbial content meets the standards, refrigerate at 4℃ for later use.

[0028] Mulberry leaf extract: Take 5 kg of dried mulberry leaves, pulverize them, and put them into a 50 L reflux extraction tank. Add 60 L of deionized water (12 times the volume). Set the extraction temperature to 90℃±2℃ and reflux for 2 hours. After the extract cools to room temperature, slowly add 95% ethanol to adjust the ethanol concentration to 70%. Stir well and let stand for 24 hours for alcohol precipitation. Remove the supernatant by siphoning. Filter the lower precipitate through a plate and frame filter, wash twice with a small amount of 70% ethanol, and then transfer to a vacuum concentration tank to concentrate to a thick paste, yielding 420 g of mulberry leaf extract. The total flavonoid content was found to be 16.8%. After meeting the microbial standards, refrigerate at 4℃ for later use.

[0029] Polygonum multiflorum ethanol extract: Take 3 kg of processed Polygonum multiflorum slices, pulverize and pass through a 50-mesh sieve, put into a 50 L reflux extraction tank, and add 27 L of 75% ethanol solution (9 times the volume). Set the extraction temperature to 85℃±2℃, and reflux extract twice, 2 hours each time. Combine the extracts and transfer to a vacuum concentration tank to concentrate to a relative density of 1.20, obtaining 580 g of brownish-black extract. The content of rhein was 1.35% and the content of chrysophanol was 0.62%. After the microbial content met the standards, it was refrigerated at 4℃ for later use.

[0030] Sophora flavescens extract: Take 4 kg of dried Sophora flavescens root, pulverize it, pass it through a 40-mesh sieve, and put it into a 50-liter ultrasonic extraction tank. Add 40 liters of 65% ethanol solution (10 times the volume of the extract). Set the extraction temperature to 55℃±2℃ and the ultrasonic power to 350W. Extract three times, 35 minutes each time. After centrifuging and filtering with a tubular centrifuge, transfer the extract to a vacuum concentration tank and concentrate it to a thick paste, obtaining 360 g of Sophora flavescens extract. The total content of matrine and oxymatrine was found to be 4.3%. After meeting the microbial standards, store at 4℃ for later use.

[0031] Ligusticum chuanxiong extract: Take 3 kg of dried rhizome of Ligusticum chuanxiong, pulverize it, pass it through a 60-mesh sieve, and put it into a 50 L reflux extraction tank. Add 24 L of 70% ethanol solution (8 times the volume of the extract). Set the extraction temperature to 80℃±2℃, and reflux extract twice, 2 hours each time. Combine the extracts and load them onto an AB-8 macroporous adsorption resin column. First, elute with 5 column volumes of deionized water at a flow rate of 2 BV per hour to remove impurities, and then elute with a gradient of 6 column volumes of 70% ethanol at a flow rate of 1.5 BV per hour. Collect the eluent, concentrate it under reduced pressure to a thick paste, and obtain 210 g of Ligusticum chuanxiong extract. The ferulic acid content was found to be 1.2%. After the microbial content met the standards, it was refrigerated at 4℃ for later use. The shelf life of all extracts was strictly controlled within 72 hours; if the shelf life was exceeded, it was prepared again.

[0032] Raw material mixing and dispersion: A 10L sterile mixing tank was selected, and the inner wall was wiped with 75% ethanol beforehand and sterilized with ultraviolet light for 30 minutes. The ingredients were precisely added according to weight: 65 parts maltodextrin, 18 parts lactose, and 0.4 parts a compound preservative of sodium dehydroacetate and potassium sorbate (mass ratio 1:1). The stirrer was started, with an initial mixing speed of 500 rpm, and mixed for 15 minutes to ensure even dispersion of the excipients. Then, the following components of the targeted inhibition core herbal group were added sequentially: 1.8 parts green tea polyphenol extract, 0.9 parts rosemary supercritical CO2 extract, 0.8 parts Poria triterpenoid purified extract, 2.5 parts Platycladus orientalis leaf ethanol extract, 1.2 parts privet fruit ethanol extract, 0.9 parts mulberry leaf extract, and 0.9 parts Polygonum multiflorum alcohol extract. Stirring was continued for 10 minutes. Next, the following components of the scalp conditioning and synergistic group were added: 0.4 parts dipotassium glycyrrhizate, 0.15 parts menthol, 0.6 parts Sophora flavescens extract, and 0.95 parts Ligusticum chuanxiong extract. Stirring was continued for 5 minutes to ensure all solid components were evenly mixed. Slowly add deionized water with a conductivity of 3.2 μS / cm and a total heavy metal content of 0.8 ppm. Adjust the solid content of the suspension to 33%, increase the stirring speed to 800 rpm, and continue stirring for 20 minutes to form a uniform suspension without agglomeration or precipitation.

[0033] Drying and shaping: An LPG-5 spray dryer was used. The equipment pipelines were pre-cleaned with deionized water and sterilized with hot air for 30 minutes. The process parameters were set as follows: inlet air temperature 160℃±5℃, outlet air temperature 70℃±3℃, atomization pressure 0.3MPa±0.05MPa, and feed rate 50mL / min±5mL / min. The suspension was fed into the spray dryer at a uniform rate using a feed pump. The spray pattern and output were observed in real time during the drying process. The dried solid particles were collected; they were pale yellow, without scorching or clumping.

[0034] Grind and sieve: The dried solid particles were transferred to a WFJ-15 aseptic pulverizer, which was pre-sterilized with ultraviolet light for 30 minutes. The pulverizing speed was set to 10,000 rpm, and the pulverizing time was 5 minutes. The pulverized material was graded through a 90-mesh standard sieve, with a vibrating screen used for assisted sieving. The undersized powder was collected and measured by a laser particle size analyzer, with a particle size of 90 micrometers.

[0035] Post-processing and warehousing: The sieved powder was transferred to a cobalt-60 gamma-ray irradiation device with an irradiation dose of 6 kGy for sterilization. After sterilization, samples were tested: moisture content 3.5%, pH 5.6 after dissolution, total bacterial count 75 CFU / g, total mold and yeast count 4 CFU / g, no detectable pathogenic bacteria, and total heavy metal content 7 ppm. All indicators met the requirements. In a Class 100 cleanroom, an automatic quantitative filling machine was used to seal the qualified powder into aluminum foil bags sterilized at 121℃ for 30 minutes, with each bag containing 20 grams of net content. After sealing, labels were affixed indicating the product name, batch number, production date, shelf life, and storage conditions. After packaging, the products were stored in a finished goods warehouse at 15-25℃ and relative humidity ≤65%, with periodic random checks on the quality of the inventory.

[0036] Example 2: Verification of the effect of extract specifications on the performance of powder compositions.

[0037] Experimental Design: Three parallel experiments were set up, with 1 kg of powder composition prepared in each group. During the experiment, only the extract specifications were changed, while the other raw material types, feeding ratios, and preparation process parameters were completely consistent with those in Example 1. The focus was on investigating the effect of extract specifications on product performance.

[0038] The qualified group: All indicators of the selected extracts met the preset standards. Among them, the EGCG content of green tea polyphenol extract was 92.5%, the rosmarinic acid content of rosemary supercritical CO2 extract was 23.1%, the total triterpenoid content of poria triterpenoid purified product was 83.7%, the solid content of arborvitae leaf ethanol extract was 50.3%, the solid content of privet fruit ethanol extract was 45%, the total flavonoid content of mulberry leaf extract was 16.8%, the emodin content of Polygonum multiflorum alcohol extract was 1.35%, the rhein content was 0.62%, the total content of matrine and oxymatrine of Sophora flavescens extract was 4.3%, and the ferulic acid content of Ligusticum chuanxiong extract was 1.2%.

[0039] Low-standard group: All indicators of the selected extracts were lower than the preset standards. Among them, the EGCG content of green tea polyphenol extract was 70%, the rosmarinic acid content of rosemary supercritical CO2 extract was 15%, the total triterpenoid content of poria triterpenoid purified extract was 60%, the solid content of arborvitae leaf ethanol extract was 35%, the solid content of privet fruit ethanol extract was 30%, the total flavonoid content of mulberry leaf extract was 10%, the emodin content of Polygonum multiflorum alcohol extract was 0.8%, the rhein content was 1.0%, the total content of matrine and oxymatrine of Sophora flavescens extract was 3.0%, and the ferulic acid content of Ligusticum chuanxiong extract was 0.8%.

[0040] The group exceeding the standard: The content of rhein in the selected Polygonum multiflorum alcohol extract was 1.6%, exceeding the preset standard range. The indicators of other extracts were also higher than the preset standards, including: EGCG content of green tea polyphenol extract 95%, rosmarinic acid content of supercritical CO2 extract of rosemary 25%, total triterpenoid content of purified Poria cocos triterpenoids 85%, solid content of Platycladus orientalis leaf ethanol extract 60%, solid content of Ligustrum lucidum ethanol extract 55%, total flavonoid content of mulberry leaf extract 20%, rhein content of Polygonum multiflorum alcohol extract 0.6%, total content of matrine and oxymatrine of Sophora flavescens extract 4.5%, and ferulic acid content of Ligusticum chuanxiong extract 1.5%.

[0041] Performance testing methods: Retention rate of active ingredients: Detected using high-performance liquid chromatography (HPLC). One gram of each of the three sample groups was accurately pipetted, added to 50 mL of methanol, and dissolved by sonication for 30 minutes. The solutions were then filtered through a 0.45 μm filter and injected into the HPLC instrument. Chromatographic conditions: C18 column, column temperature 30℃; mobile phase: methanol and water; flow rate 1.0 mL / min; detection wavelengths: EGCG 278 nm, rosmarinic acid 330 nm, total triterpenes 254 nm, matrine 220 nm. The content of each active ingredient was calculated based on the peak area, and the retention rate was calculated in conjunction with the feed amount.

[0042] Physicochemical and safety indicators: Powder particle size was measured using a laser particle size analyzer; moisture content was measured using a Karl Fischer moisture analyzer; 1 gram of powder was added to 50 ml of deionized water, stirred and dissolved, and the pH value was measured using a precision pH meter; the total bacterial count, mold and yeast counts were measured using the plate count method according to the standard method for microbiological testing, and pathogenic bacteria were detected using selective culture media; the total heavy metal content was measured using inductively coupled plasma mass spectrometry.

[0043] Practical indicators: Add 1 gram of powder to 50 ml of deionized water, stir at room temperature, record the time required for complete dissolution, and observe whether there is precipitation or stratification after dissolution; use the fixed funnel method to determine the angle of repose of the powder and evaluate its flowability.

[0044] Results and Analysis: Retention rate of active ingredients: In the compliant group, the retention rates of all key active ingredients were above 90%, with EGCG retention rate at 91.8%, rosmarinic acid retention rate at 90.7%, total triterpenoid retention rate at 90.2%, and matrine retention rate at 91.3%. In the low-compliant group, the retention rates of all active ingredients were only between 67% and 71%, with EGCG retention rate at 67%, rosmarinic acid retention rate at 68%, total triterpenoid retention rate at 69%, and matrine retention rate at 71%. Furthermore, due to excessive levels of emodin in the Polygonum multiflorum alcohol extract, the emodin content in the finished product reached 0.86%. In the non-compliant group, the retention rates of all active ingredients were above 92%, with EGCG retention rate at 92.3%, rosmarinic acid retention rate at 93.1%, total triterpenoid retention rate at 92.5%, and matrine retention rate at 92.8%. However, due to excessive levels of emodin in the Polygonum multiflorum alcohol extract, the emodin content in the finished product reached 1.39%.

[0045] Physicochemical and safety indicators: The compliant group had a powder particle size of 88 micrometers, a moisture content of 3.3%, and a pH of 5.5 after dissolution; microbiological testing showed a total bacterial count of 75 CFU / g, a total mold and yeast count of 4 CFU / g, and no detectable pathogens; the total heavy metal content was 7 ppm. All indicators met the preset requirements. The low-standard group had a powder particle size of 95 micrometers, a moisture content of 4.9%, and a pH of 5.4 after dissolution; microbiological testing showed a total bacterial count of 130 CFU / g, exceeding the preset limit, a total mold and yeast count of 8 CFU / g, and no detectable pathogens; the total heavy metal content was 8 ppm, and other indicators were close to the preset upper limit. The exceeding group had a powder particle size of 85 micrometers, a moisture content of 3.1%, and a pH of 5.6 after dissolution; all microbiological testing indicators met the requirements; the total heavy metal content was 9.7 ppm, close to the preset upper limit, but it did not meet safety requirements due to excessive levels of emodin in Polygonum multiflorum.

[0046] Practical Indicators: The compliant group of powder dissolves quickly in water, completely within 30 seconds, producing a homogeneous solution without sedimentation or stratification; the angle of repose is 29 degrees, indicating excellent flowability and ease of application. The low-compliant group of powder dissolves more slowly, with a small amount of undissolved particles remaining after 45 seconds, and slight sedimentation at the bottom after 10 minutes of standing; the angle of repose is 36 degrees, indicating poor flowability and requiring repeated stirring during use. The excessive group of powder dissolves quickly, completely within 28 seconds, producing a homogeneous solution; the angle of repose is 28 degrees, indicating excellent flowability, but due to excessive components, it cannot be used as a qualified product.

[0047] Conclusion: The comparison of the three sets of experimental results shows that only by selecting extracts that meet the preset standards can the powder composition simultaneously meet the requirements of safe compliance in terms of active ingredient retention rate and ease of use. Extracts with low standards will result in low active ingredient retention rate, excessive microbial levels, and poor performance; while extracts with excessive standards may improve the retention rate of some active ingredients, they pose safety risks. Therefore, extracts that meet the specified standards must be selected for composition preparation.

[0048] Example 3: Optimization and verification of the effect of drying process on the properties of powder composition.

[0049] Experimental Design: Using the retention rate of active ingredients, physicochemical stability, and practicality as the core evaluation indicators, two groups of different drying methods were set up. 800 grams of powder composition were prepared in each group. Other raw material pretreatment and preceding processes remained consistent with Example 1. The focus was on investigating the effects of spray drying and freeze drying on product performance. Specific process parameters are shown in the table below:

[0050] Performance testing methods: Retention rate of active ingredients: The total triterpenoid content of EGCG rosmarinic acid was detected by high performance liquid chromatography for the two finished products and after 6 months of storage. The retention rate of each component was calculated as follows: retention rate = content after storage ÷ initial content × 100%.

[0051] Physicochemical properties: Powder particle size was measured using a laser particle size analyzer; moisture content was measured using a Karl Fischer moisture analyzer; 1 gram of powder was added to 50 ml of deionized water, and the time required for complete dissolution was recorded; the angle of repose was measured using the fixed funnel method to evaluate flowability.

[0052] Stability: After sealing the two components, store them in a constant temperature and humidity chamber at 25℃ and 65% relative humidity. Observe the appearance of the powder every 3 months and record whether clumping or discoloration occurs. Test the microbial limit after 6 months to determine whether it meets the requirements.

[0053] Results and Analysis: Retention rates of active ingredients: For the spray-dried product, the retention rates of EGCG (91.5%), rosmarinic acid (90.3%), and total triterpenes (89.8%) were as follows: After 6 months of storage, the retention rates of EGCG (88.1%), rosmarinic acid (87.2%), and total triterpenes (86.5%) were as follows. For the freeze-dried product, the retention rates of EGCG (93.2%), rosmarinic acid (92.5%), and total triterpenes (91.4%) were as follows: After 6 months of storage, the retention rates of EGCG (89.8%), rosmarinic acid (89.1%), and total triterpenes (88.0%) were as follows: The data show that the retention rates of active ingredients in the freeze-dried group are slightly higher than those in the spray-dried group, but the difference is not significant, and both groups effectively retain the active ingredients.

[0054] Physicochemical properties: Spray-dried powder: particle size 86 micrometers, moisture content 3.4%, complete dissolution time 26 seconds, angle of repose 28 degrees; powder is uniformly pale yellow, without lumps or impurities. Freeze-dried powder: particle size 93 micrometers, moisture content 2.7%, complete dissolution time 42 seconds, angle of repose 32 degrees; powder is also pale yellow, but the particles are slightly coarser. The comparison shows that the spray-dried product has better solubility and flowability, better meeting the needs of topical products for immediate dissolution and easy application.

[0055] Stability: After 6 months of storage, the spray-dried powder showed no clumping, no moisture absorption, and maintained a uniform pale yellow color, consistent with its initial state. Microbiological testing showed a total bacterial count of 72 CFU / g, a total mold and yeast count of 5 CFU / g, and no detectable pathogenic bacteria, meeting the requirements. The freeze-dried powder showed slight clumping, which could be dispersed into powder by gentle hand grinding, with no significant color change. Microbiological testing indicators also met the requirements, but the clumping affected ease of use.

[0056] In conclusion, considering the overall physicochemical properties and stability of the active ingredient retention rate, spray drying is more suitable for the large-scale production of the powder composition of this invention. Although the freeze-dried group has a slightly higher active ingredient retention rate, the spray-dried group's products have better solubility and flowability, better meeting the needs of immediate dissolution for external use. Furthermore, it offers higher production efficiency and lower cost, while achieving the designed standards for active ingredient retention rate and stability.

[0057] Example 4: Optimization of the effect of mixing parameters on the uniformity of powder composition.

[0058] Experimental Design: Using component uniformity and solubility as the core evaluation indicators, three different combinations of stirring parameters were set up for the raw material mixing and dispersion process. 600 grams of powder composition were prepared for each combination, with other process steps remaining consistent with Example 1. The focus was on investigating the impact of initial mixing speed and suspension stirring time on product performance. Specific parameters are shown in the table below:

[0059] Performance testing methods: Component uniformity: 10 samples were randomly selected from each group, each weighing 1 gram. The EGCG content in each sample was detected by high performance liquid chromatography. The relative standard deviation of the EGCG content of the 10 samples was calculated. A relative standard deviation ≤ 3% was considered to be of excellent uniformity.

[0060] Solubility: Take 1 gram of each sample and add 50 ml of deionized water. Stir at room temperature and observe the dispersion state after dissolution. Check for any precipitation or agglomeration. Score according to the following standards: 10 points: completely dissolved with no precipitation or agglomeration; 7 points: basically dissolved with a small amount of fine precipitation; 4 points: partially dissolved with obvious precipitation or agglomeration.

[0061] Results and Analysis: Component uniformity: The relative standard deviation of EGCG content in the 10 samples of Group 1 was 4.1%, exceeding the excellent standard of 3%, indicating that the initial mixing speed was too low and the stirring time of the suspension was too short, resulting in uneven mixing of the components, with some areas having higher EGCG content and others lower. The relative standard deviation of EGCG content in the 10 samples of Group 2 was 2.4%, meeting the excellent standard, indicating that the mixing parameters of this group can fully disperse the components and achieve good powder uniformity. The relative standard deviation of EGCG content in the 10 samples of Group 3 was 2.2%, with slightly better uniformity than Group 2, but the difference was minimal.

[0062] Solubility: After dissolving, the sample in Group 1 showed a small amount of fine precipitate, which increased slightly after standing for 10 minutes, resulting in a solubility score of 7.3. The sample in Group 2 dispersed completely after dissolving, with no precipitate or agglomeration, and the solution was a uniform pale yellow, resulting in a solubility score of 9.1. The solubility of the sample in Group 3 was similar to that of Group 2, with a score of 9.2. However, the stirring time for the suspension in Group 3 was 3 minutes longer than that in Group 2, leading to increased production time per batch, reduced production efficiency, and no significant improvement in uniformity or solubility.

[0063] In conclusion, considering the overall uniformity of components, solubility, and production efficiency, the optimal mixing parameters are an initial mixing speed of 500 rpm and an initial mixing time of 15 minutes, and a suspension stirring speed of 800 rpm and a suspension stirring time of 20 minutes. This combination of parameters ensures thorough mixing of all components and excellent powder uniformity while achieving good solubility, and avoids a decrease in production efficiency due to excessive stirring time, making it suitable for industrial production.

[0064] Example 5: Product storage condition stability verification.

[0065] Experimental Design: The qualified finished product prepared in Example 1 was selected and divided into three groups, with 20 bags per group and 20 grams per bag. These were placed in different storage environments for a period of 24 months. Various performance indicators of the product were periodically tested, and the effects of storage temperature and relative humidity on product stability were investigated. Specific storage parameters are shown in the table below.

[0066] Performance testing methods: Appearance observation: Observe the appearance of the powder every 3 months and record whether there is clumping, moisture absorption and discoloration. Use a standard colorimetric card to compare the color changes. A difference of ≤0.5 indicates no obvious color change, and a difference >1.0 indicates a significant darkening of the color.

[0067] Physicochemical indicators: The particle size, moisture content, and pH value after dissolution are tested every 6 months. The change in the initial value is compared with the change in the pH value. The change in the pH value is ≤5% and the indicator is considered stable.

[0068] Active ingredients and microorganisms: The content of EGCG matrine was detected by high performance liquid chromatography every 6 months, and the content change rate was calculated as follows: change rate = (initial content - content after storage) ÷ initial content × 100%; the total number of bacteria, molds and yeasts and pathogens were detected according to the standard method for microbial testing.

[0069] Results and Analysis: Appearance Changes: Group 1: During the 24-month storage period, the powder remained loose, without clumping or moisture absorption; the color remained a uniform pale yellow, with a color difference of 0.4 compared to the initial state, showing no significant change. Group 2: After 6 months of storage, the powder began to show slight moisture absorption, feeling sticky to the touch; after 12 months, moisture absorption worsened, with noticeable clumping, the clumps being quite hard and requiring vigorous grinding to disperse; after 24 months, the color deepened significantly, with a color difference of 1.4, and a slight odor appeared. Group 3: After 24 months of storage, the powder showed no clumping or discoloration, with a color difference of 0.3. However, after being removed from the refrigerated environment, due to the increase in temperature and changes in ambient humidity, moisture easily condensed on the powder surface, resulting in temporary moisture absorption. It must be opened and used immediately, otherwise moisture absorption will worsen.

[0070] Physicochemical indicators: Group 1, after 24 months of storage, had a particle size of 90 micrometers (initial particle size 88 micrometers), a change of 2.3%; a moisture content of 3.7% (initial moisture content 3.5%), a change of 5.7%; and a pH value of 5.5 (initial pH value 5.6), a change of 1.8%. All indicators showed minimal changes and good stability. Group 2, after 24 months of storage, had a particle size of 118 micrometers, a change of 34.1%; a moisture content of 5.6%, exceeding the initial moisture content of 3.5% and the standard of ≤5.0%; and a pH value of 5.2, a change of 7.1%. All physicochemical indicators showed significant abnormalities. Group 3, after 24 months of storage, had a particle size of 89 micrometers, a change of 1.1%; a moisture content of 3.5%, a change of 0%; and a pH value of 5.6, with no change. The stability of the physicochemical indicators was similar to Group 1, but the moisture absorption issue affected the user experience.

[0071] Active Ingredients and Microorganisms: In Group 1, after 24 months of storage, the EGCG content changed by 5.6%, and the matrine content changed by 5.1%, indicating good retention of active ingredients. Microbiological testing showed a total bacterial count of 70 CFU / g, a total mold and yeast count of 4 CFU / g, and no detectable pathogens, meeting the requirements. In Group 2, after 24 months of storage, the EGCG content changed by 13.2%, and the matrine content changed by 12.5%, indicating significant degradation of active ingredients. Microbiological testing showed a total bacterial count of 145 CFU / g, exceeding the standard of ≤100 CFU / g, a total mold and yeast count of 12 CFU / g, and no detectable pathogens, increasing the risk of microbial contamination. In Group 3, after 24 months of storage, the EGCG content changed by 5.0%, and the matrine content changed by 4.7%, with a slightly better retention rate of active ingredients than Group 1. Microbiological testing indicators met the requirements, but the moisture absorption problem limited its application scenarios, making it unsuitable for frequent opening after long-term storage.

[0072] In conclusion, considering the overall appearance, physicochemical properties, active ingredient retention rate, and microbial stability, the optimal storage conditions for the powder composition of this invention are a dry environment at room temperature with a relative humidity of ≤65% and a temperature of 15-25°C. Under these storage conditions, the product maintains stable performance within its 24-month shelf life, effectively preventing clumping, moisture absorption, and discoloration, reducing active ingredient degradation, controlling the risk of microbial contamination, and eliminating the need for pre-conditioning to adapt to the temperature before use, thus avoiding condensation and moisture absorption. This meets the storage and usage requirements for external use products. High temperature and high humidity environments accelerate product deterioration, while low temperature refrigeration, although better preserving active ingredients, carries the risk of moisture absorption; neither is recommended for long-term storage.

[0073] The above description is merely a preferred embodiment of the present invention and is not intended to limit the present invention in any way. Although the present invention has been disclosed above with reference to preferred embodiments, it is not intended to limit the present invention. Any person skilled in the art can make some modifications or alterations to the above-disclosed technical content to create equivalent embodiments without departing from the scope of the present invention. Any simple modifications, equivalent changes and alterations made to the above embodiments based on the technical essence of the present invention without departing from the scope of the present invention shall still fall within the scope of the present invention.

Claims

1. A natural Chinese herbal hair care composition, characterized in that, By weight, the composition comprises: 8-12 parts of a core herbal medicine group targeting inhibition, 2-3 parts of a scalp conditioning and synergistic group, and 85-90 parts of a pharmaceutical excipient adaptation system; the core herbal medicine group targeting inhibition is composed of the following components: 1.5-2 parts of green tea polyphenol extract, 0.8-1 parts of rosemary supercritical CO2 extract, 0.5-1 parts of purified poria triterpenoids, 2-3 parts of arborvitae leaf ethanol extract, 1-1.5 parts of privet fruit ethanol extract, 0.8-1 parts of mulberry leaf extract, and 0.5-1 parts of Polygonum multiflorum alcohol extract. 8-1 parts; the scalp conditioning and synergistic group consists of the following components: dipotassium glycyrrhizate 0.4-0.5 parts, menthol 0.1-0.2 parts, sophora flavescens extract 0.5-0.8 parts, chuanxiong extract 0.8-1 parts; the pharmaceutical excipient formulation system consists of the following components: maltodextrin 60-70 parts, lactose 15-20 parts, sodium dehydroacetate / potassium sorbate compound preservative 0.3-0.5 parts; the sum of the weight parts of each component is 100 parts, the composition is in powder form, and is used for external hair care after being dissolved in water.

2. The natural herbal hair-nourishing composition according to claim 1, characterized in that, The specifications of each component in the core Chinese herbal medicine group for targeted inhibition are as follows: EGCG content of green tea polyphenol extract ≥90%, rosmarinic acid content of rosemary supercritical CO2 extract ≥20%, total triterpenoid content of Poria triterpenoid purified extract ≥80%, solid content of Platycladus orientalis leaf ethanol extract approximately 50%, solid content of Ligustrum lucidum ethanol extract approximately 45%, total flavonoid content of mulberry leaf extract ≥15%, and emodin content of Polygonum multiflorum ethanol extract 1.2%-1.5% and chrysophanol content ≤0.8%.

3. The natural herbal hair-nourishing composition according to claim 1, characterized in that, In the scalp conditioning and synergistic group, the total content of matrine and oxymatrine in Sophora flavescens extract is ≥4.0%, and the content of ferulic acid in Ligusticum chuanxiong extract is ≥1.0%; in the pharmaceutical excipient adaptation system, the mass ratio of sodium dehydroacetate / potassium sorbate compound preservative is 1:1, the DE value of maltodextrin is 10-20, and the purity of lactose is ≥99%.

4. The natural herbal hair-nourishing composition according to claim 1, characterized in that, The physicochemical properties of the composition are as follows: particle size ≤100μm, moisture content ≤5.0%, pH value after dissolution 5.5-6.0; microbial limits: total bacterial count ≤100CFU / g, total mold and yeast count ≤10CFU / g, pathogenic bacteria not detectable; total heavy metal content ≤10ppm.

5. A method for preparing a natural herbal hair-nourishing composition, wherein the method is used to prepare the natural herbal hair-nourishing composition according to any one of claims 1-4, characterized in that, The specific steps of this preparation method are as follows: S1, Targeted preparation and purification of extracts: Select traditional Chinese medicinal materials from authentic producing areas, remove impurities and crush them, and prepare each traditional Chinese medicinal material extract using corresponding extraction and purification techniques. After passing the test, weigh them for later use. S2, Raw material mixing and dispersion: In a sterile mixing tank, maltodextrin and lactose from the pharmaceutical excipient adaptation system are added in sequence, followed by the extracts of the core Chinese herbal medicine group for targeted inhibition and the components of the scalp conditioning and synergistic group. Stirring is started and the mixture is mixed evenly. Then, an appropriate amount of deionized water is slowly added and stirred to form a uniform suspension. S3, Drying and Shaping: The suspension obtained in step S2 is dried by spray drying or freeze drying to remove moisture and obtain solid particles; S4, Grinding and sieving: Transfer the solid particles obtained in step S3 into a sterile grinding device for grinding. After grinding, pass them through an 80-100 mesh standard sieve and collect the powder that passes through the sieve. S5, Post-processing and warehousing: The sieved powder is sterilized, and the particle size, moisture content, and microbial limits are tested. After passing the sampling inspection, it is sealed and packaged in a clean environment and stored in the warehouse.

6. The method for preparing a natural herbal hair-nourishing composition according to claim 5, characterized in that, In step S1, the particle size of the pulverized Chinese herbal raw materials is controlled as follows: rosemary leaves, tender branches and leaves of arborvitae, and dried roots of sophora flavescens ≤450μm, processed Polygonum multiflorum slices ≤300μm, and dried rhizome of Ligusticum chuanxiong ≤250μm; the microbial limits of each extract are: total bacterial count ≤100CFU / g, total mold and yeast count ≤10CFU / g, and pathogenic bacteria not detectable. After passing the test, the extracts are stored at 4-8℃ for storage for ≤72 hours.

7. The method for preparing a natural herbal hair-nourishing composition according to claim 5, characterized in that, In step S1, the corresponding extraction and purification techniques are as follows: rosemary is extracted using supercritical CO2 extraction, Poria cocos is purified using ultrasound-assisted alcohol extraction-AB-8 type macroporous adsorption resin, green tea is concentrated using low-temperature membrane separation, Platycladus orientalis leaves and Ligusticum chuanxiong are extracted using ethanol reflux extraction, Ligustrum lucidum and Sophora flavescens are extracted using ultrasound alcohol extraction, mulberry leaves are extracted using water extraction and alcohol precipitation, and Polygonum multiflorum is extracted using ethanol reflux extraction.

8. The method for preparing a natural herbal hair-nourishing composition according to claim 5, characterized in that, In step S2, during the stirring and mixing: the initial mixing speed is 500 rpm ± 50 rpm, and the mixing time is 15 minutes ± 2 minutes; after adding deionized water, the suspension is stirred at a speed of 800 rpm ± 100 rpm for 20 minutes ± 3 minutes.

9. The method for preparing a natural herbal hair-nourishing composition according to claim 5, characterized in that, In step S3, the spray drying process specifically includes: inlet air temperature 160℃±5℃, outlet air temperature 70℃±3℃, atomization pressure 0.3MPa±0.05MPa, and feed rate 50mL / min±5mL / min; the freeze drying process specifically includes: pre-freezing temperature -40℃±5℃, pre-freezing time 4 hours±0.5 hours, sublimation drying temperature -10℃±2℃, desorption drying temperature 30℃±2℃, vacuum degree 0.01MPa±0.002MPa, and total drying time 24 hours±2 hours.

10. The method for preparing a natural herbal hair-nourishing composition according to claim 5, characterized in that, In step S4, the pulverizing speed is 10000rpm±1000rpm and the pulverizing time is 5 minutes±1 minute; in step S5, the sterilization treatment is carried out by gamma irradiation with an irradiation dose of 5kGy-8kGy; the packaging container is a sterilized aluminum foil sealed bag.

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