Biopsy system and sampling device thereof

Abstract

The invention discloses a biopsy system and a sampling device thereof, and relates to the technical field of medical equipment. The biopsy sampling device comprises a sampling soft rod, a sampling column and biopsy forceps which are connected in sequence, the sampling column is rotationally connected with the sampling soft rod; the rotating axis of the sampling column coincides with the axis of the sampling column; the adjusting structure is arranged on the sampling column; during use, the adjusting structure is used for transmitting driving force to the sampling column, and the driving force is used for driving the sampling column to rotate. The sampling soft rod, the sampling column and the biopsy forceps are sequentially connected, and the sampling column and the sampling soft rod are designed to be of a coaxial rotating connection structure, so that the traditional mode of directly rotating the sampling soft rod to adjust the angle of the biopsy forceps is abandoned, and the problems that the sampling soft rod is insufficient in rigidity, large in friction with a sampling channel, irregular in resistance and high in sampling accuracy are fundamentally solved. And the angle regulation and control deviation of the biopsy forceps is large.

Description

Technical Field

[0001] This application relates to the field of medical device technology, specifically to a biopsy system and its sampling device. Background Technology

[0002] In the field of clinical endoscopy, biopsy is widely used and is currently the gold standard for confirming the nature of tissue lesions. During endoscopic examinations of the biliary tract, gastrointestinal tract, and other sites, clinicians can obtain tissue samples from lesions using biopsy forceps, cutting, clamping, or puncture. Pathological analysis of these tissue samples allows for precise determination of the nature, type, degree of differentiation, and extent of invasion of the lesion, thus clarifying the pathological diagnosis of the lesion.

[0003] Endoscopic biopsy requires inserting instruments into the target organ or tissue through natural body cavities or surgical incisions. During the procedure, the biopsy forceps, propelled by a sampling rod, travels through the endoscope's sampling channel to the intended lesion site. When retrieving foreign objects or diseased tissue, the angle of the biopsy forceps often needs to be adjusted to obtain the desired tissue. However, clinically used endoscopes are often over 1 meter long, and the sampling rod itself lacks rigidity. Furthermore, significant friction exists between the sampling rod and the endoscope's sampling channel, making it difficult for the operator to precisely control the angle of the biopsy forceps when rotating the sampling rod. This significantly increases the difficulty of adjusting the biopsy forceps angle during endoscopic biopsy procedures. Summary of the Invention

[0004] The purpose of this application is to provide a biopsy system and its sampling device to solve the technical problem that the angle of the biopsy forceps is difficult to precisely control in the prior art.

[0005] To achieve the above objectives, this application provides the following technical solution:

[0006] Firstly, this application proposes a technical solution for a biopsy sampling device. The biopsy sampling device includes: A sampling rod, a sampling column, and a biopsy forceps are connected in sequence; the sampling column and the sampling rod are rotatably connected; the rotation axis of the sampling column coincides with the center line of the sampling column. An adjustment structure is provided on the sampling column; in use, the adjustment structure is used to transmit a driving force to the sampling column, and the driving force is used to drive the sampling column to rotate.

[0007] As a specific solution in this application, the sampling rod has a liquid flow channel inside, the sampling column has a hollow cavity inside, and the liquid flow channel is connected to the hollow cavity; the adjustment structure includes a plurality of through holes disposed on the sampling column, each through hole being uniformly arrayed around the axis of the sampling column, and the axis of each through hole forming a straight line skew to the axis of the sampling column.

[0008] As a specific solution in this application, the spatial angle between the first direction and the second direction is an acute angle; the first direction is parallel to the axis of any through hole and points from the inlet to the outlet of the through hole; the second direction is parallel to the axis of the sampling column and points from the head end to the tail end of the sampling column.

[0009] As a specific solution in this application, the adjustment structure includes: The adjusting tube is movably sleeved on the outside of the sampling column, forming a sliding connection with the sampling column along the axial direction of the sampling column; The first control wire is connected to the regulating tube; An inclined groove is provided on the outer wall of the sampling column; A sliding block is disposed on the inner wall of the regulating tube, and the sliding block is adapted to the inclined groove.

[0010] Secondly, this application proposes a technical solution for a biopsy system. The biopsy system includes: Biopsy sampling device as described in any of the first aspects; An endoscope body and an endoscopic cannula are connected in sequence; the endoscopic cannula has a sampling channel inside, and the sampling channel is compatible with the biopsy sampling device; The camera module and lighting components are both located inside the endoscope body and the endoscopic cannula.

[0011] As a specific solution in this application, the camera module includes a signal plug, a transmission cable and an optical end connected in sequence; the inside of the endoscopic tube is also provided with a camera channel, which is adapted to the transmission cable and the optical end, and a transparent observation window is provided at the first end of the camera channel.

[0012] As a specific solution in this application, the endoscope body is provided with an injection tube, and the inside of the endoscopic cannula is also provided with an inlet channel, and the injection tube and the inlet channel are connected.

[0013] As a specific solution in this application, the end of the endoscopic cannula is further provided with a sampling groove, the inner diameter of which is larger than the inner diameter of the sampling channel, and the sampling groove is adapted to the biopsy forceps.

[0014] As a specific solution in this application, the tip of the endoscopic cannula is a flexible part, and the biopsy system further includes an adjustment component, which is used to adjust the deflection direction of the flexible part.

[0015] As a specific embodiment of the technical solution in this application, the adjustment component includes: a second control wire and a third control wire; both the second control wire and the third control wire are connected to the head end of the flexible part, and the second control wire and the third control wire are evenly distributed around the axial direction of the endoscopic cannula; The biopsy system further includes: a winding wheel; the winding wheel is rotatably mounted on the endoscope body; the tail end of the second control wire is connected to one side of the winding wheel; and the tail end of the third control wire is connected to the other side of the winding wheel.

[0016] Compared with the prior art, the beneficial effects of this application are: This application addresses the technical problems of insufficient rigidity of the sampling rod, high friction with the sampling channel, and irregular resistance, which lead to large deviations in the angle adjustment of the biopsy forceps, by sequentially connecting the sampling rod, sampling column, and biopsy forceps, and designing the sampling column and sampling rod as a coaxial rotating connection. Simultaneously, an adjustment structure is incorporated into the sampling column, directly transmitting driving force and causing the column to rotate around its own axis. The fixed connection between the sampling column and the biopsy forceps allows the rotation of the sampling column to synchronously adjust the angle of the biopsy forceps. This reduces friction between the sampling column and the sampling channel and makes it easier to control, achieving precise angle control of the biopsy forceps. This reduces the operational difficulty of angle adjustment in endoscopic biopsy procedures and is suitable for clinical biopsy procedures in the biliary tract, gastrointestinal tract, and other areas. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the structure of a biopsy system proposed in an embodiment of this application; Figure 2 This is a schematic diagram of the structure of a camera module proposed in an embodiment of this application; Figure 3 A biopsy system proposed in the embodiments of this application is based on Figure 1 Schematic diagram of the cross section of line AA; Figure 4 A biopsy system proposed in the embodiments of this application is based on Figure 3 Schematic diagram of the cross section of the middle BB line; Figure 5 This is a schematic diagram of the structure of a biopsy sampling device proposed in an embodiment of this application; Figure 6This is a schematic diagram of the structure of another biopsy sampling device proposed in the embodiments of this application; Figure 7 This is a schematic diagram of the structure of an adjustment component proposed in an embodiment of this application.

[0018] In the diagram: 1. Endoscope body; 21. Sampling rod; 22. Sampling column; 221. Inclined slide; 222. Through hole; 23. Biopsy forceps; 3. Endoscopic cannula; 31. Camera channel; 32. Sampling channel; 33. Sampling groove; 34. Transparent observation window; 35. Liquid inlet channel; 36. Flexible part; 4. Adjustment structure; 41. First control wire; 42. Adjustment tube; 421. Sliding block; 5. Camera module; 51. Optical end; 52. Transmission cable; 53. Signal plug; 6. Adjustment assembly; 61. Second control wire; 62. Third control wire; 63. Winding wheel; 7. Injection tube; 8. Illumination assembly. Detailed Implementation

[0019] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0020] It should be noted that in the description of this application, the terms "upper", "lower", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inner", "outer", etc., indicate the orientation or positional relationship based on the orientation or positional relationship shown in the accompanying drawings. They are only for the convenience of describing this application and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation. Therefore, they should not be construed as limitations on this application.

[0021] Furthermore, it should be understood that, for ease of description, the dimensions of the various components shown in the accompanying drawings are not drawn to actual scale; for example, the thickness or width of some layers may be exaggerated relative to other layers.

[0022] It should be noted that similar labels and letters in the following figures indicate similar items. Therefore, once an item is defined or described in one figure, it will not need to be discussed or described in detail in the description of the subsequent figures.

[0023] It should be noted that the structures used to guide fluid (e.g., physiological saline or mannitol as described below) in this application (e.g., inlet channel 35 and through hole 222, etc.) all have inlets and outlets. An inlet refers to the opening through which fluid enters the structure during use, while an outlet refers to the opening through which fluid flows out of the structure during use. In other words, in the embodiments of this application, during use, the fluid always flows from the inlet to the outlet of a certain structure.

[0024] It should be noted that the components used for insertion into the human body in this application (e.g., endoscopic cannula 3, sampling soft rod 21, and sampling column 22) all have a head end and a tail end. The head end refers to the end of the component that first enters the human body during use; the tail end refers to the end of the component that enters the human body after the head end or does not enter the human body during use.

[0025] It is important to understand that in this embodiment, the reason why it is difficult to precisely control the angle of the biopsy forceps by rotating the sampling rod is as follows: Since the sampling rod is often over one meter long and lacks sufficient rigidity, there is significant friction between the outer wall of the sampling rod and the inner wall of the sampling channel when the rod moves within the endoscope's sampling channel. The magnitude of this friction is greatly influenced by the shape of the sampling rod within the sampling channel and is highly random. This increases the difficulty for the operator to rotate the sampling rod, leading to a significant deviation between the actual rotation angle of the biopsy forceps and the operator's expected angle (for example, rotating the tail end of the sampling rod 10 times is expected to rotate the biopsy forceps 90°, but the forceps actually rotate 180°; changing the rotation from 10 times to 9 times is expected to rotate the forceps 45°, but the forceps do not actually rotate).

[0026] To address the technical problem mentioned in the background art regarding the difficulty in precisely controlling the angle of biopsy forceps, this application proposes an embodiment of a biopsy sampling device. Specifically, the biopsy sampling device includes a sampling rod 21, a sampling column 22, biopsy forceps 23, and an adjustment structure 4. For example... Figure 5 and Figure 6 As shown, the sampling rod 21, sampling column 22, and biopsy forceps 23 are connected in sequence. The sampling column 22 and the sampling rod 21 are rotatably connected, and the rotation axis of the sampling column 22 coincides with the center line of the sampling column 22. An adjustment structure 4 is provided on the sampling column 22; in use, the adjustment structure 4 is used to transmit driving force to the sampling column 22, and the driving force is used to drive the sampling column 22 to rotate.

[0027] In this embodiment, through the addition and structural design of the sampling column 22, the sampling rod 21 and the biopsy forceps 23 form a separate coaxial rotating connection structure. This design optimizes the force and transmission logic of the angle adjustment of the biopsy forceps 23 from a structural perspective, improving the shortcomings of the traditional adjustment method. In the traditional method, when directly rotating the sampling rod 21 to adjust the angle, a large frictional force is generated between the sampling rod 21 and the sampling channel 32, and this frictional force is highly uncontrollable: because the length of the sampling rod 21 required for biopsy operations is mostly over 1 meter, the placement of the long sampling rod 21 in the slender sampling channel 32 is completely unpredictable, resulting in an irregular contact area between the sampling rod 21 and the sampling channel 32. Since the magnitude of the frictional force is directly related to the contact area, the frictional force between the sampling rod 21 and the sampling channel 32 is not only numerically large, but also highly random and unpredictable, greatly hindering precise adjustment. In contrast, the sampling column 22 is a short columnar structure, and its contact with the sampling channel 32 is a regular local contact with a basically constant and controllable contact area. Therefore, the frictional force generated between the sampling column 22 and the sampling channel 32 is much smaller than that between the sampling rod 21 and the sampling channel 32, and the resistance value is stable and easier for the operator to control. At the same time, this embodiment has a special adjustment structure 4 on the sampling column 22. This structure can directly transmit a precise rotational driving force to the sampling column 22. This rotational driving force can directly drive the sampling column 22 to complete a stable rotation around its own axis. Since the sampling column 22 and the biopsy forceps 23 are fixedly connected and there is no relative rotation between them, the rotational movement of the sampling column 22 will be transmitted synchronously and without deviation to the biopsy forceps 23, driving the biopsy forceps 23 to complete the corresponding angle adjustment, thereby achieving precise and controllable adjustment of the angle of the biopsy forceps 23.

[0028] In this embodiment, to facilitate control of the sampling rod 21, such as... Figure 1 As shown, a control handle can also be provided at the end of the sampling rod 21 to facilitate the operator's control of the sampling rod 21.

[0029] It should be clear that in the application of endoscopic biopsy, both the sampling rod 21 and the biopsy forceps 23 are mature technologies, and will not be elaborated here.

[0030] In this embodiment, the shape and structure of the sampling column 22 are not limited. For example, the sampling column 22 can be cylindrical. To avoid the sampling column 22 scratching human organs or tissues, the sampling column 22 can also be as follows: Figure 5 As shown, it is a columnar shape with rounded ends.

[0031] In this embodiment, no restrictions are placed on the adjustment structure 4, as long as the adjustment structure 4 can transmit driving force to the sampling column 22 to cause the sampling column 22 to rotate. For example, the adjustment structure 4 can be as shown in Embodiment 1 and Embodiment 2 below.

[0032] Example 1 of the adjustment structure In this embodiment, the adjustment structure 4 includes a first control wire 41 and an adjustment tube 42. Wherein, as... Figure 5 As shown, the adjusting tube 42 is movably sleeved on the outside of the sampling column 22, and the adjusting tube 42 and the sampling column 22 form a sliding connection along the axial direction of the sampling column 22. The first control wire 41 is connected to the adjusting tube 42. The outer wall of the sampling column 22 is provided with an inclined groove 221, and the inner wall of the adjusting tube 42 is provided with a sliding block 421, and the sliding block 421 and the inclined groove 221 are adapted to each other.

[0033] In this embodiment, the matching of the sliding block 421 and the inclined groove 221 means that the outer dimensions of the sliding block 421 match the inner groove dimensions of the inclined groove 221. The sliding block 421 can be completely embedded in the inner space of the inclined groove 221, and the sliding block 421 can slide smoothly along the extension direction of the inclined groove 221 without jamming or looseness. At the same time, the contact surface between the sliding block 421 and the inclined groove 221 can achieve effective force transmission. When the adjusting tube 42 is displaced along the axial direction of the sampling column 22, the sliding block 421 can apply a rotational driving force to the sampling column 22 through contact with the inclined groove 221, thereby driving the sampling column 22 to complete the rotation around its own axis.

[0034] In this embodiment, if it is necessary to adjust the angle of the biopsy forceps 23, the first control wire 41 can be pushed or pulled so that the front end of the first control wire 41 can drive the adjustment tube 42 and the sampling column 22 to generate an axial relative displacement. If an axial relative displacement occurs between the adjustment tube 42 and the sampling column 22, the sliding block 421 on the inner wall of the adjustment tube 42 will slide smoothly along the inclined groove 221 on the outer wall of the sampling column 22. During the sliding process of the sliding block 421 along the inclined groove 221, the sliding block 421 will apply a rotational driving force to the sampling column 22 through contact with the inclined groove 221. This rotational driving force will directly drive the sampling column 22 to complete the rotation action around its own axis. Since the sampling column 22 and the biopsy forceps 23 are fixedly connected, the rotation action of the sampling column 22 will synchronously drive the biopsy forceps 23 to rotate at the same angle, and finally achieve precise adjustment of the angle of the biopsy forceps 23.

[0035] In other embodiments of this application, the sliding block 421 may be disposed on the outer wall of the sampling column 22, and the inclined groove 221 may be disposed on the inner wall of the adjusting tube 42.

[0036] Example 2 of the adjustment structure In this embodiment, as Figure 6 As shown, the sampling rod 21 has a liquid flow channel inside, and the sampling column 22 has a hollow cavity inside, with the liquid flow channel connected to the hollow cavity. The adjustment structure 4 includes multiple through holes 222 disposed on the sampling column 22. Each through hole 222 is uniformly arrayed around the axis of the sampling column 22, and the axis of each through hole 222 forms a straight line that is not in the same plane as the axis of the sampling column 22.

[0037] In this embodiment, if the angle of the biopsy forceps 23 needs to be adjusted, fluid at a preset pressure (e.g., 10 kPa or 0.05 MPa) can be injected into the liquid channel inside the sampling rod 21. The fluid can enter the hollow cavity inside the sampling column 22 along the liquid channel of the sampling rod 21 and flow outward from each through hole 222 on the sampling column 22. Since the axis of each through hole 222 is a straight line skew to the axis of the sampling column 22, the fluid will generate a reaction force on the inner wall of the through hole 222 as it flows out of the through hole 222. This reaction force can be decomposed into a component force along the axial direction of the sampling column 22 and a rotational component force around the axis of the sampling column 22. The component force along the axial direction of the sampling column 22 will not drive the sampling column 22 to rotate, while the rotational component force around the axis of the sampling column 22 will directly act as a driving force on the sampling column 22. Meanwhile, the through holes 222 are evenly arrayed around the axis of the sampling column 22, which allows the rotational components generated by each through hole 222 to be superimposed to form a stable rotational resultant force. This rotational resultant force can continuously and stably drive the sampling column 22 to complete the rotation around its own axis. Since the sampling column 22 and the biopsy forceps 23 are fixedly connected, the rotation of the sampling column 22 will synchronously drive the biopsy forceps 23 to rotate at the same angle, ultimately achieving precise adjustment of the angle of the biopsy forceps 23.

[0038] In this embodiment, there are no major restrictions on the fluid injected into the liquid channel, as long as the fluid will not cause harm to human organs or tissues. For example, the fluid can be sterile saline, sterile water for injection, low-concentration mannitol injection, sterile medical lubricant, or other commonly used harmless medical fluids.

[0039] In this embodiment, since the rotational resultant force formed by the fluid acting on the sampling column 22 is positively correlated with the fluid pressure in the liquid channel inside the sampling rod 21 (i.e., the greater the fluid pressure, the greater the rotational resultant force, and the faster the sampling column 22 rotates), in actual use, the operator can determine the optimal fluid pressure that drives the sampling column 22 to rotate slowly by gradually increasing the fluid pressure injected into the liquid channel inside the sampling rod 21. This optimal fluid pressure allows the sampling column 22 to maintain a slow and stable rotation, and can simultaneously drive the biopsy forceps 23 to perform smooth angle adjustment. This not only meets the core operational requirement of precise angle control of the biopsy forceps 23 in endoscopic biopsy surgery, but also avoids deviation in the angle adjustment of the biopsy forceps 23 caused by excessively rapid rotation of the sampling column 22, and also prevents unnecessary damage to internal organs or tissues caused by excessively rapid rotation of the sampling column 22.

[0040] It should be noted that in the medical field, adjusting the pressure of the fluid in the flow channel is a mature technology. For example, a conventional method of using a medical precision injection pump with a pressure regulating valve can be adopted. By adjusting the fluid delivery rate of the injection pump or directly controlling the opening of the pressure regulating valve, the fluid pressure flowing into the liquid flow channel of the sampling rod 21 can be precisely changed, and the driving force that drives the sampling column 22 to rotate can be matched as needed.

[0041] It should be noted that in applications where the friction between the sampling column 22 or biopsy forceps 23 and the endoscopic cannula 3 is high, a higher fluid pressure is required to rotate the sampling column 22. If the fluid pressure is high, the fluid jet ejected from the through-hole 222 will have a higher velocity. To avoid damage to human organs or tissues from these fluid jets, in one embodiment of this application, the first direction (i.e., as...) Figure 6 The direction shown is D) and the second direction (i.e., as shown) Figure 6 The spatial angle between directions C and C is an acute angle. The first direction is parallel to the axis of any through hole 222 and points from the inlet to the outlet of the through hole 222; the second direction is parallel to the axis of the sampling column 22 and points from the head to the tail of the sampling column 22.

[0042] In this embodiment, since the spatial angle between the first and second directions is acute, the main jet direction of the fluid flowing out of the through-hole 222 will be biased towards the axial direction of the sampling column 22 and extend towards the tail end of the sampling column 22. It will not directly face the human organs or tissues around the sampling column 22. Even if the fluid pressure is high, resulting in a high jet velocity of the fluid jet from the through-hole 222, the fluid jet is unlikely to directly impact the human organs and tissues around the sampling column 22, effectively avoiding impact damage to the internal organs or tissues of the human body caused by the high-speed fluid jet. In particular, in the scenario where the biopsy forceps 23 extends out of the sampling channel 32 or the sampling groove 33 (hereinafter referred to as the sampling slot 33), while each through-hole 222 is still inside the sampling channel 32 or the sampling groove 33 (hereinafter referred to as the sampling slot 33), the fluid jetting from the through-hole 222 will directly act on the inner wall of the sampling channel 32 or the sampling groove 33, without directly contacting the diseased tissue and surrounding normal organs and tissues of the human body, fundamentally avoiding the problem of impact damage to the internal tissues of the human body caused by the high-speed fluid jet.

[0043] This concludes the description of Embodiment 2 of the adjustment structure.

[0044] The embodiments of the biopsy sampling device proposed in this application, by sequentially connecting the sampling rod, sampling column, and biopsy forceps, and designing the sampling column and sampling rod as a coaxial rotating connection, abandon the traditional method of directly rotating the sampling rod to adjust the angle of the biopsy forceps. This fundamentally solves the technical problems of insufficient rigidity of the sampling rod, high friction with the sampling channel, and irregular resistance, which lead to large deviations in the angle adjustment of the biopsy forceps. At the same time, an adjustment structure is set in the sampling column, which can directly transmit driving force to the sampling column and drive the sampling column to rotate around its own axis. The fixed connection between the sampling column and the biopsy forceps allows the rotation of the sampling column to synchronously drive the biopsy forceps to complete the angle adjustment. The friction between the sampling column and the sampling channel is smaller and easier to control, achieving precise control of the angle of the biopsy forceps, reducing the operational difficulty of angle adjustment in endoscopic biopsy surgery, and adapting to the needs of biopsy operations in clinical biliary tract, gastrointestinal tract, and other sites.

[0045] Having described the biopsy sampling device proposed in the embodiments of this application, the following describes a biopsy system proposed in this application. This biopsy system includes an endoscope body 1, an endoscopic cannula 3, a camera module 5, an illumination assembly 8, and a biopsy sampling device. In this embodiment, the biopsy sampling device in the biopsy system is the biopsy sampling device proposed in any of the above embodiments. For example... Figure 1 As shown, the endoscope body 1 and the endoscopic cannula 3 are connected in sequence. The endoscopic cannula 3 has a sampling channel 32 inside, which is adapted to the biopsy sampling device. The camera module 5 and the illumination component 8 are both located inside the endoscope body 1 and the endoscopic cannula 3.

[0046] In this embodiment, the compatibility of the sampling channel 32 with the biopsy sampling device means that the inner diameter of the sampling channel 32 needs to match the outer diameter of the sampling rod 21, sampling column 22, and biopsy forceps 23 of the biopsy sampling device. This ensures that the sampling rod 21, sampling column 22, and biopsy forceps 23 can smoothly advance and retract along the axial direction of the sampling channel 32 without excessive looseness or jamming. For example, the outer diameter of the sampling channel 32 can be greater than or equal to the outer diameter of the sampling rod 21, sampling column 22, and the retracted biopsy forceps 23.

[0047] In this embodiment, the endoscope body 1 is the part of the biopsy system that is exposed outside the human body during use, and the endoscopic cannula 3 is the part of the biopsy system that is inserted into the human body during use. In use, if a biopsy system is needed to obtain a sample of lesion tissue from a patient's body, the endoscopic cannula 3 must first be inserted gradually through the body's natural cavities or surgical incision to the vicinity of the target lesion. Simultaneously, the illumination component 8 is activated to provide continuous illumination to the operating area at the tip of the endoscopic cannula 3. The camera module 5, through its optical end 51, works with the endoscopic cannula 3 to capture real-time images of the target area. This image information is then transmitted sequentially via the transmission cable 52 and signal plug 53 to an external display device (e.g., a display screen or monitor). The operator can clearly observe the actual condition of the target lesion through the external display device. Further, the operator needs to gradually advance the sampling rod 21, sampling column 22, and biopsy forceps 23 of the biopsy sampling device through the sampling channel 32 of the endoscopic cannula 3 until the biopsy forceps 23 extends out of the endoscopic cannula 3 and is positioned beside the target lesion tissue. Further, the operator needs to adjust the sampling column 22... The adjustment structure 4 precisely adjusts the angle of the biopsy forceps 23. If the adjustment structure 4 includes a first control wire 41, the first control wire 41 can be pushed or pulled to adjust the angle of the biopsy forceps 23. If the adjustment structure 4 includes a through hole 222, a medically safe fluid with a preset pressure can be injected into the liquid channel inside the sampling rod 21 to adjust the angle of the biopsy forceps 23 until the clamping end of the biopsy forceps 23 is precisely aligned with the preset sampling position of the target lesion tissue. Furthermore, the operator can manipulate the biopsy forceps 23 to complete the clamping operation of the target lesion tissue, ensuring that the lesion tissue sample is stably clamped at the clamping end of the biopsy forceps 23. After the lesion tissue sample is clamped, the sampling rod 21, sampling column 22, and biopsy forceps 23 of the biopsy sampling device need to be gradually retracted backward through the sampling channel 32 of the endoscopic cannula 3 until the entire biopsy sampling device is completely removed from the endoscopic cannula 3. Then, the clamped lesion tissue sample can be removed from the biopsy forceps 23.

[0048] In this embodiment, the endoscope portion of the biopsy system (i.e., the portion excluding the biopsy sampling device) can be reused. It is important to note that while traditional reusable endoscopes have undergone continuous technological innovation, their inherent drawbacks have not been completely resolved: on the one hand, even with strict adherence to cleaning and disinfection protocols, the risk of cross-infection from reusable endoscopes remains difficult to completely eliminate, posing a potential threat to clinical safety; on the other hand, the daily maintenance and replacement of parts for the endoscope's associated disinfection and cleaning equipment incurs long-term and ongoing operating costs. Against this industry backdrop, disposable endoscopes, with their innovative "one endoscope per person, use and discard" application model, have achieved a breakthrough in both technology and application. This not only physically eliminates the risk of cross-infection from reuse at its source, but also has significant clinical value in controlling the spread of multidrug-resistant bacteria, while saving on the high and ongoing costs associated with purchasing disinfection equipment, hiring professional cleaning personnel, and annual equipment maintenance. In this embodiment, the camera module 5, as the core component of the biopsy system for realizing visualized sampling operations, is extremely expensive. Therefore, its reusability is crucial to the overall cost of controlling the equipment in one-off application scenarios. To enable the camera module 5 to be reused in one-off application scenarios, in one embodiment of this application, as follows... Figure 2 As shown, the camera module 5 includes a signal plug 53, a transmission cable 52, and an optical end 51 connected in sequence. Figure 4 As shown, the endoscopic cannula 3 is also equipped with a camera channel 31 inside. The camera channel 31 is adapted to the transmission cable 52 and the optical end 51. A transparent observation window 34 is provided at the beginning of the camera channel 31.

[0049] In this embodiment, the compatibility of the camera channel 31 with the transmission cable 52 and the optical end 51 means that the inner diameter of the camera channel 31 matches the outer diameter of the transmission cable 52 and the optical end 51. This ensures that the optical end 51 and the transmission cable 52 can be smoothly inserted, removed, and moved along the axial direction of the camera channel 31 without excessive looseness or jamming. For example, the inner diameter of the camera channel 31 can be greater than or equal to the outer diameter of the transmission cable 52 and the optical end 51.

[0050] In use, if it is necessary to observe the condition of diseased tissues or organs in a patient's body through the camera module 5 and camera channel 31, the optical end 51 of the camera module 5 and the transmission cable 52 need to be pushed forward along the camera channel 31 of the endoscope 3 until the optical end 51 reaches the transparent observation window 34 at the beginning of the camera channel 31 (this step can be performed before the endoscope 3 is inserted into the patient's body). Then, the camera module 5 is activated, allowing the optical end 51 to capture real-time image information of the target area in the patient's body through the transparent observation window 34. The captured real-time image information is then transmitted sequentially via the transmission cable 52 and signal plug 53 to an external display device. If necessary, the illumination component 8 can be turned on to provide continuous illumination to the operating area at the front end of the endoscope 3, improving the clarity of the images captured by the optical end 51. In endoscope applications, both the camera module 5 and the illumination component 8 are mature technologies and will not be elaborated upon here.

[0051] This embodiment, through the setting of the camera channel 31 and the transparent observation window 34, ensures that the camera module 5 does not directly contact the patient without affecting the acquisition of image information inside the patient's body. This avoids contamination caused by direct contact between the camera module and the patient's internal tissues and fluids, eliminating the risk of cross-infection caused by the camera module 5 contacting the patient at the source. Simultaneously, it protects the precision components of the camera module 5, such as the optical end 51, from contamination, wear, or corrosion by the human physiological environment, ensuring stable imaging performance. In this embodiment, the endoscope body 1 and the endoscopic cannula 3 can be designed as disposable consumables, which can be discarded after use. The camera module 5 can be completely removed from the camera channel 31 of the endoscopic cannula 3 and reassembled into the camera channel 31 of a new endoscopic cannula 3 for continued use. Furthermore, the optical end 51 of the camera module 5 can stably capture real-time image information inside the patient's body through the transparent observation window 34, and its imaging function is not affected by insertion, removal, and reuse. This achieves the reuse of the camera module 5, thereby controlling the overall usage cost of the biopsy system.

[0052] It should be clear that in some application scenarios, it is necessary to rinse the diseased organ or tissue in order to observe the lesion of the diseased organ or tissue clearly using the camera module 5. In order to facilitate the observation of the diseased organ, in one embodiment of this application, the endoscope body 1 is provided with an injection tube 7, and the endoscopic cannula 3 is also provided with an inlet channel 35. The injection tube 7 and the inlet channel 35 are connected.

[0053] When in use, if it is necessary to clean the patient's organ for easier observation, the cleaning solution (such as physiological saline or medical lubricant mentioned above) can be injected into the inlet channel 35 through the injection tube 7 using the injection device. The cleaning solution flowing out of the inlet channel 35 can then clean the organ or tissue.

[0054] In the embodiments of this application, the injection device can be any device capable of injecting cleaning fluid into the injection tube 7, such as a syringe or a syringe pump.

[0055] As mentioned earlier, the inner diameter of the sampling channel 32 needs to be greater than or equal to the maximum outer diameter of the sampling rod 21, sampling column 22, and biopsy forceps 23. This ensures that the biopsy sampling device can smoothly perform movements such as advancement and retraction within the sampling channel 32. Among the sampling rod 21, sampling column 22, and biopsy forceps 23, the outer diameter of the biopsy forceps 23 is generally the largest. This is because the structural design of the biopsy forceps 23 needs to meet the clinical requirements of stably gripping and obtaining a sufficient amount of lesion tissue samples. The structural dimensions of the gripping end of the biopsy forceps 23 determine that the outer diameter of the biopsy forceps 23 cannot be excessively reduced. This also means that the inner diameter of the sampling channel 32 needs to be designed to match the outer diameter of the biopsy forceps 23. However, on the other hand, the overall structure of the endoscopic cannula 3 needs to have sufficient mechanical strength to ensure that the endoscopic cannula 3 can be smoothly inserted into the target site inside the human body to complete the biopsy operation. If the inner diameter of the sampling channel 32 is increased simply to accommodate the outer diameter of the biopsy forceps 23, it will directly cause the overall outer diameter of the endoscopic cannula 3 to increase accordingly. When the outer diameter of the endoscopic cannula 3 is too large, without increasing or widening the surgical incision or performing additional dilation procedures, the endoscopic cannula 3 will have difficulty entering the lesion area of ​​human organs or tissues with relatively narrow lumens, such as the bile duct or uterine cavity. This makes the biopsy system unsuitable for biopsy procedures in such narrow cavities in clinical practice. To solve this problem, in one embodiment of this application, such as Figure 4 As shown, the end of the endoscopic cannula 3 is also provided with a sampling groove 33. The inner diameter of the sampling groove 33 is larger than the inner diameter of the sampling channel 32, and the sampling groove 33 is compatible with the biopsy forceps 23.

[0056] In this embodiment, the sampling slot 33 is compatible with the biopsy forceps 23, meaning that the inner diameter, axial length and internal contour of the sampling slot 33 match the shape and working stroke of the biopsy forceps 23, so that it can fully accommodate the retracted biopsy forceps 23, and the biopsy forceps 23 can be smoothly moved in and out of the sampling slot 33 by pushing or pulling the sampling rod 21.

[0057] In this embodiment, since the sampling slot 33 is adapted to the biopsy forceps 23, and the outer diameter of the biopsy forceps 23 is larger than the outer diameter of the sampling column 22, there is a large gap between the sampling column 22 and the sampling slot 33 after the biopsy forceps 23 is pushed out of the sampling slot 33. If the gap between the sampling column 22 and the sampling slot 33 is large, the friction between the sampling column 22 and the sampling slot 33 is small, which makes it easier for the operator to rotate the sampling column 22 by adjusting the structure 4, and also makes it easier to adjust the angle of the biopsy forceps 23.

[0058] In use, if it is necessary to collect lesion tissue samples using biopsy forceps 23, the biopsy forceps 23 can be pushed out from inside the sampling slot 33 using the sampling lever 21 and positioned beside the target lesion tissue. Further, the angle of the biopsy forceps 23 is precisely adjusted using the adjustment structure 4 set in the sampling column 22 until the clamping end of the biopsy forceps 23 is precisely aligned with the preset sampling position of the target lesion tissue. After the angle of the biopsy forceps 23 is adjusted, the operator needs to manipulate the biopsy forceps 23 to complete the clamping operation on the target lesion tissue, ensuring that the lesion tissue sample is stably clamped at the clamping end of the biopsy forceps 23. Further, the biopsy forceps 23 is retracted to the sampling slot 33 using the sampling lever 21. Further, the endoscopic cannula 3 is withdrawn from the body. Finally, the clamped lesion tissue sample can be removed from the biopsy forceps 23 in the sampling slot 33, completing the entire lesion tissue sample collection operation.

[0059] In this embodiment, the sampling slot 33 eliminates the need for the sampling channel 32 to be designed to match the outer diameter of the biopsy forceps 23. This effectively reduces the inner diameter of the sampling channel 32, thereby allowing for reasonable control of the overall outer diameter of the endoscopic cannula 3. This enables the endoscopic cannula 3 to smoothly enter narrow cavities such as the bile duct and uterine cavity, meeting the biopsy requirements for these narrow cavities. Furthermore, the sampling slot 33 provides suitable space for the biopsy forceps 23 to move. After the biopsy forceps 23 is extended out of the sampling slot 33, a larger gap is formed between the sampling column 22 and the sampling slot 33, reducing the friction between them. This allows the adjustment structure 4 to drive the sampling column 22 to rotate more smoothly, further improving the accuracy of the angle adjustment of the biopsy forceps 23 and ensuring the smooth operation of lesion tissue sampling.

[0060] It should be noted that in some application scenarios, the orientation of the tip of the endoscopic cannula 3 needs to be adjusted so that the operator can clearly observe the condition of various parts of the patient's body with the help of the camera module 5 and obtain lesion tissue samples from the required locations through the biopsy sampling device. To facilitate the adjustment of the orientation of the tip of the endoscopic cannula 3, in one embodiment of this application, the tip of the endoscopic cannula 3 can be a flexible part 36, and the biopsy system also includes an adjustment component 6, which is used to adjust the deflection direction of the flexible part 36.

[0061] In this embodiment, the flexible part 36 refers to the structure at the tip of the endoscopic cannula 3 that has flexible deformation capability. This structure can undergo controllable elastic deflection under the action of external force, and can change its deflection direction under the drive of the adjustment component 6.

[0062] In this embodiment, the material of the flexible part 36 is not subject to many restrictions. As long as the material of the flexible part 36 is elastic, will not irritate the internal organs or tissues of the human body, and can withstand the physiological environment inside the human body without material degradation or deformation, it is acceptable. For example, the flexible part 36 can be made of medical-grade food-grade silicone, polyurethane elastomer, or medical-grade fluororubber.

[0063] In this embodiment, the advantage of providing the flexible part 36 is that, on the one hand, the elastic flexible part 36 is easy to deflect under the control of the adjustment component 6, which can drive the end of the endoscope tube 3 to flexibly adjust its orientation, allowing the camera module 5 to clearly capture tissue images at different locations inside the human body, and enabling the biopsy sampling device to accurately target lesions in different directions, meeting the needs of multi-directional observation and sampling operations in clinical practice; on the other hand, compared with the relatively rigid end of the endoscope tube 3, the more flexible end of the endoscope tube 3 can better adapt to the curvature of the human body's natural cavities during insertion, and can adapt to the shape of the cavity with flexible deformation, without causing hard compression and scraping to the inner wall of the human body cavity, thereby reducing the risk of mechanical damage to internal organs or tissues during the insertion and advancement of the endoscope tube 3.

[0064] In this embodiment, the adjustment component 6 can be any component capable of adjusting the deflection direction of the flexible part 36. For example, the adjustment component 6 can be the control part disclosed in patent application document CN119867621A, entitled "A Control Part and its Endoscope" (hereinafter referred to as Prior Art 1). The control part in Prior Art 1 has a complex structure and high manufacturing cost, making it unsuitable for single-use applications. Therefore, in one embodiment of this application, the adjustment component 6 may include a second control wire 61 and a third control wire 62. Both the second control wire 61 and the third control wire 62 are connected to the head end of the flexible part 36, and as shown... Figure 3 As shown, the second control wire 61 and the third control wire 62 are evenly distributed around the axial direction of the endoscopic cannula 3.

[0065] When in use, if the second control wire 61 and the third control wire 62 are not pushed or pulled, the flexible part 36 will be as follows: Figure 1The wire is shown in a straight position. If the tail end of the second control wire 61 is pulled and the tail end of the third control wire 62 is pushed, the length of the portion of the second control wire 61 located in the flexible portion 36 will shorten, and the length of the portion of the third control wire 62 located in the flexible portion 36 will lengthen. Since the beginning ends of both the second control wire 61 and the third control wire 62 are connected to the beginning end of the flexible portion 36, if the length of the portion of the second control wire 61 located in the flexible portion 36 shortens and the length of the portion of the third control wire 62 located in the flexible portion 36 lengthens, the beginning end of the flexible portion 36 will definitely deflect towards the side closer to the second control wire 61. Similarly, if the tail end of the second control wire 61 is pushed and the tail end of the third control wire 62 is pulled, the beginning end of the flexible portion 36 will definitely deflect towards the side closer to the third control wire 62. That is to say, in the embodiments of this application, the deflection direction of the tail end of the flexible portion 36 can be adjusted by pushing or pulling the tail end of the second control wire 61 or the tail end of the third control wire 62.

[0066] In this embodiment, there are no restrictions on the materials of the second control wire 61 and the third control wire 62, as long as the second control wire 61 and the third control wire 62 can control the corresponding deflection of the head end of the flexible part 36. For example, the second control wire 61 and the third control wire 62 can be made of plastic (e.g., polyamide or polycarbonate) or metal (e.g., iron or steel). The same applies to the first control wire 41 mentioned above, which will not be described in detail here.

[0067] In this embodiment, the deflection direction of the flexible part can be adjusted by pushing or pulling the second or third control wire. It has a simple structure, low manufacturing cost, and is suitable for single-use applications.

[0068] As described above, in the embodiments of this application, during use, by pushing one of the second control wire 61 and the third control wire 62, and then pulling the other, the lengths of the second control wire 61 and the third control wire 62 within the flexible portion 36 change, thereby causing the head end of the flexible portion 36 to deflect. That is, in this embodiment, at least two actions are required to deflect the head end of the flexible portion 36. To simplify the above operation steps, in one embodiment of this application, such as... Figure 7 As shown, the biopsy system also includes a winding wheel 63. The winding wheel 63 is rotatably mounted on the endoscope body 1, and the tail end of the second control wire 61 is connected to one side of the winding wheel 63; the tail end of the third control wire 62 is connected to the other side of the winding wheel 63.

[0069] In this embodiment, since the tail end of the second control wire 61 is connected to one side of the winding wheel 63, and the tail end of the third control wire 62 is connected to the other side of the winding wheel 63, if the winding wheel 63 rotates, the lengths of the second control wire 61 and the third control wire 62 within the flexible portion 36 will necessarily change in opposite directions. For example, if the winding wheel 63 rotates forward to tighten the second control wire 61 (i.e., the length of the second control wire 61 within the flexible portion 36 becomes shorter), the third control wire 62 will necessarily be released (i.e., the length of the third control wire 62 within the flexible portion 36 becomes longer); if the winding wheel 63 rotates in the opposite direction to release the second control wire 61, the third control wire 62 will necessarily be tightened. In other words, in this embodiment, only one action—rotating the winding wheel 63—is needed to cause the tail end of the flexible portion 36 to deflect, making the operation simple.

[0070] The embodiments of the biopsy system proposed in this application, by sequentially connecting the sampling rod, sampling column, and biopsy forceps, and designing the sampling column and sampling rod as a coaxial rotating connection, abandon the traditional method of directly rotating the sampling rod to adjust the angle of the biopsy forceps. This fundamentally solves the technical problems of insufficient rigidity of the sampling rod, high friction with the sampling channel, and irregular resistance, which lead to large deviations in the angle adjustment of the biopsy forceps. At the same time, an adjustment structure is set in the sampling column, which can directly transmit driving force to the sampling column and drive the sampling column to rotate around its own axis. The fixed connection between the sampling column and the biopsy forceps allows the rotation of the sampling column to synchronously drive the biopsy forceps to complete the angle adjustment. The friction between the sampling column and the sampling channel is smaller and easier to control, achieving precise control of the angle of the biopsy forceps, reducing the operational difficulty of angle adjustment in endoscopic biopsy surgery, and adapting to the needs of biopsy operations in clinical biliary tract, gastrointestinal tract, and other sites.

[0071] Although embodiments of this application have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of this application, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A biopsy sampling device, characterized in that, include: The sampling rod (21), sampling column (22), and biopsy forceps (23) are connected in sequence; the sampling column (22) and the sampling rod (21) are rotatably connected; the rotation axis of the sampling column (22) coincides with the center line of the sampling column (22); An adjustment structure (4) is provided on the sampling column (22); in use, the adjustment structure (4) is used to transmit driving force to the sampling column (22), and the driving force is used to drive the sampling column (22) to rotate.

2. The biopsy sampling device according to claim 1, characterized in that, The sampling rod (21) has a liquid flow channel inside, and the sampling column (22) has a hollow cavity inside. The liquid flow channel is connected to the hollow cavity. The adjustment structure (4) includes a plurality of through holes (222) disposed on the sampling column (22). Each through hole (222) is uniformly arrayed around the axis of the sampling column (22), and the axis of each through hole (222) forms a straight line with the axis of the sampling column (22).

3. The biopsy sampling device according to claim 2, characterized in that, The spatial angle between the first direction and the second direction is an acute angle; the first direction is parallel to the axis of any through hole (222) and points from the inlet of the through hole (222) to the outlet; the second direction is parallel to the axis of the sampling column (22) and points from the head end of the sampling column (22) to the tail end.

4. The biopsy sampling device according to claim 1, characterized in that, The adjustment structure (4) includes: The regulating tube (42) is movably sleeved on the outside of the sampling column (22) and forms a sliding connection with the sampling column (22) along the axial direction of the sampling column (22); The first control wire (41) is connected to the regulating tube (42); Inclined groove (221) is provided on the outer wall of the sampling column (22); A sliding block (421) is disposed on the inner wall of the regulating tube (42), and the sliding block (421) is adapted to the inclined groove (221).

5. A biopsy system, characterized in that, include: The biopsy sampling device as described in any one of claims 1 to 4; An endoscope body (1) and an endoscope cannula (3) are connected in sequence; the endoscope cannula (3) is provided with a sampling channel (32) inside, and the sampling channel (32) is adapted to the biopsy sampling device; The camera module (5) and the lighting component (8) are both located inside the endoscope body (1) and the endoscope cannula (3).

6. The biopsy system according to claim 5, characterized in that, The camera module (5) includes a signal plug (53), a transmission cable (52) and an optical end (51) connected in sequence; the endoscope tube (3) is also provided with a camera channel (31), which is adapted to the transmission cable (52) and the optical end (51), and the head end of the camera channel (31) is provided with a transparent observation window (34).

7. The biopsy system according to claim 5, characterized in that, The endoscope body (1) is provided with an injection tube (7), and the endoscope cannula (3) is also provided with an inlet channel (35). The injection tube (7) and the inlet channel (35) are connected.

8. The biopsy system according to claim 5, characterized in that, The end of the endoscopic cannula (3) is also provided with a sampling groove (33), the inner diameter of the sampling groove (33) is larger than the inner diameter of the sampling channel (32), and the sampling groove (33) is adapted to the biopsy forceps (23).

9. The biopsy system according to claim 5, characterized in that, The end of the endoscopic cannula (3) is a flexible part (36), and the biopsy system also includes an adjustment component (6) for adjusting the deflection direction of the flexible part (36).

10. The biopsy system according to claim 9, characterized in that, The adjustment assembly (6) includes a second control wire (61) and a third control wire (62); the second control wire (61) and the third control wire (62) are both connected to the head end of the flexible part (36), and the second control wire (61) and the third control wire (62) are evenly distributed around the axial direction of the endoscopic cannula (3); The biopsy system further includes: a winding wheel (63); the winding wheel (63) is rotatably mounted on the endoscope body (1); the tail end of the second control wire (61) is connected to one side of the winding wheel (63); the tail end of the third control wire (62) is connected to the other side of the winding wheel (63).

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