A triazole phosphorus pesticide, a preparation method and application thereof

Abstract

The present application relates to the technical field of pesticide preparation, in particular to a triazophos pesticide, a preparation method and application thereof, comprising triazophos and a stabilizer, the mass ratio of the triazophos to the stabilizer is 100:0.1-1, and the stabilizer is a weakly acidic organic substance. The present application also provides a preparation method of the triazophos pesticide, wherein the triazophos is mixed with the stabilizer, and stirred until uniform. The present application also provides application of the triazophos pesticide in preparing an insecticide for preventing and treating pests of rice or cotton. The present application also provides a triazophos pesticide composition, comprising the triazophos pesticide, and a pesticide-acceptable carrier and / or adjuvant. The present application uses a trace amount of weakly acidic organic substance as a stabilizer, which can significantly improve the stability of triazophos, thereby prolonging the shelf life of the product.

Description

Technical Field

[0001] This invention relates to the field of pesticide formulation technology, specifically to a triazophos pesticide, its preparation method, and its application. Background Technology

[0002] Triazophos insecticides are safe, highly effective, and easy to use, and are widely used on crops such as cotton and rice. However, triazophos is chemically unstable and easily decomposes over long periods of storage, leading to reduced efficacy and a shortened shelf life. Summary of the Invention

[0003] In order to overcome the shortcomings of the existing technology, the purpose of this invention is to provide a triazophos pesticide, its preparation method and application, which can significantly improve the stability of triazophos and thus improve the shelf life of the product.

[0004] To achieve the above objectives, the present invention adopts the following technical solution:

[0005] In a first aspect, the present invention provides a triazophos pesticide, comprising triazophos technical and a stabilizer, wherein the mass ratio of the triazophos technical to the stabilizer is 100:0.1 to 1, and the stabilizer is a weakly acidic organic compound.

[0006] Furthermore, the mass ratio of the triazophos technical to the stabilizer is 100:0.3-0.6.

[0007] Furthermore, the weakly acidic organic compound is any one of formic acid, acetic acid, propionic acid, and butyric acid.

[0008] Preferably, the weakly acidic organic compound is acetic acid.

[0009] Preferably, the mass ratio of the triazophos technical to the acetic acid is 100:0.45.

[0010] Furthermore, the mass concentration of the triazophos technical is 90-95%.

[0011] In a second aspect, the present invention provides a method for preparing triazophos pesticide according to any one of the above claims, wherein a stabilizer is added to triazophos technical material and stirred until the mixture is uniform.

[0012] Furthermore, the mixing step is carried out in a moisture-free environment.

[0013] Thirdly, the present invention provides the application of any one of the above-mentioned triazophos pesticides in the preparation of insecticides for controlling pests of rice or cotton.

[0014] Fourthly, the present invention provides a triazophos pesticide composition comprising any of the triazophos pesticides described above, and a pesticide-acceptable carrier and / or adjuvant.

[0015] Compared with the prior art, the present invention has the following beneficial effects:

[0016] (1) The present invention uses a small amount of weakly acidic organic matter as a stabilizer, which can significantly improve the stability of triazophos, thereby improving the shelf life of the product, ensuring that users can obtain the indicated efficacy when using it, and reducing the prevention and control failure and economic losses caused by product degradation;

[0017] (2) The decomposition rate of the triazophos pesticide of the present invention can be as low as 1.1% after being stored at 54℃±2℃ for 14 days, which significantly improves the stability of triazophos.

[0018] (3) The stabilizer used in this invention is inexpensive and widely available. It only needs to be added to the triazophos technical and stirred evenly. The process is simple and it is easy to achieve large-scale industrial production and promotion. The economic benefits are significant. Detailed Implementation

[0019] The technical solutions in the embodiments of the present invention will be clearly and completely described below. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0020] Unless otherwise specified, all raw materials used in the following examples and comparative examples are commercially available products.

[0021] Triazophos is a thiophosphate compound. Its ester and PS bonds are prone to hydrolysis under strong acid and strong base conditions, leading to the degradation of the active ingredient. Moreover, the hydrolysis rate under alkaline conditions is much greater than that under acidic conditions.

[0022] To address the above problems, this embodiment provides a triazophos pesticide, comprising triazophos technical and a stabilizer, wherein the mass ratio of the triazophos technical to the stabilizer is 100:0.1-1, and the stabilizer is a weakly acidic organic compound.

[0023] This embodiment adds a trace amount of weakly acidic organic matter to triazophos technical grade. On the one hand, the addition of the weakly acidic organic matter can neutralize trace alkaline impurities that may be introduced into the triazophos technical grade during production and storage, stabilizing the pH of the system within a relatively stable neutral or weakly acidic range, thus minimizing the hydrolysis rate of triazophos. On the other hand, the carboxyl groups contained in the weakly acidic organic matter can form hydrogen bond networks with ester bonds and other bonds in the triazophos group, preventing water molecules from approaching the easily hydrolyzed chemical bonds in the triazophos molecule, thereby reducing the hydrolysis reaction rate. Through the synergistic effect of creating the most stable conditions and spatially increasing the energy barrier of the hydrolysis reaction, the stability of triazophos is significantly improved, thereby extending the product's shelf life, ensuring that users obtain the labeled efficacy during use, and reducing the prevention and control failures and economic losses caused by product degradation.

[0024] Furthermore, the mass ratio of the triazophos technical to the stabilizer is 100:0.3-0.6. By designing the mass ratio of triazophos technical to stabilizer to be 100:0.3-0.6, a better effect on improving the stability of the triazophos technical is ensured. When the mass ratio of stabilizer to triazophos technical exceeds 1:100, the excess stabilizer will trigger acid-catalyzed hydrolysis of triazophos, which will actually increase the hydrolysis rate.

[0025] Furthermore, the weakly acidic organic compound is any one of formic acid, acetic acid, propionic acid, and butyric acid. Formic acid, acetic acid, propionic acid, and butyric acid not only have sufficient acidity to effectively adjust the pH of the system, but also have small molecular weights and low steric hindrance, allowing them to rapidly diffuse around the triazole phosphorus molecule and form a hydrogen bond network.

[0026] Preferably, the weakly acidic organic compound is acetic acid. When the mass ratio of triazophos technical to stabilizer is the same, acetic acid exhibits better stabilizing effect on triazophos compared to formic acid, propionic acid, and butyric acid.

[0027] Preferably, the mass ratio of the triazophos technical grade to the acetic acid is 100:0.45. At this mass ratio, the decomposition rate of the active ingredient of triazophos pesticide after accelerated heat storage at 54℃±2℃ for 14 days can be reduced to about 1.1%, exhibiting the best stabilizing effect on triazophos.

[0028] Furthermore, the mass concentration of the triazophos technical is 90-95%, that is, the mass percentage of the effective component of triazophos in the triazophos technical is preferably 90-95%.

[0029] This embodiment also provides a method for preparing the triazophos pesticide described in any of the above embodiments, comprising adding a stabilizer to the triazophos technical material and stirring until the mixture is homogeneous. This preparation method is simple and easily scalable for large-scale industrial production and widespread application.

[0030] Furthermore, the mixing step is carried out in a moisture-free environment. That is, the steps of "adding stabilizer to triazophos technical material, stirring until uniformly mixed" are all carried out in a moisture-free environment, which is either an inert gas (such as nitrogen or argon) protective environment or a vacuum environment.

[0031] This embodiment also provides the application of the triazophos pesticide described in any one of the above embodiments in the preparation of an insecticide for controlling pests of rice or cotton. The rice or cotton pests are pests that harm rice or cotton; specifically, rice pests include, but are not limited to, rice stem borers and rice leaf rollers, and cotton pests include, but are not limited to, cotton bollworms.

[0032] This embodiment also provides a triazophos pesticide composition comprising any one of the triazophos pesticides described above, and a pesticide-acceptable carrier and / or adjuvant. The triazophos pesticide comprises 1-50% by mass in the composition, and the formulation of the composition can be a conventional formulation in the art, such as an emulsifiable concentrate, microemulsion, water-in-oil emulsion, or soluble concentrate.

[0033] The stability of the pesticide of the present invention will be described in detail below through the following examples.

[0034] Comparative Example

[0035] Take 10.00 g of triazophos technical with a mass concentration of 90%, add it to an ampoule and seal it. Then place it in a constant temperature oven at 54℃±2℃ and store it for 14 days. After that, take it out and determine that the content of triazophos technical has become 78% and its decomposition rate is 13%.

[0036] Example 1

[0037] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.02g of propionic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 85%, and its relative decomposition rate was 5.6%.

[0038] Example 2

[0039] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.02g of butyric acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 86%, and its relative decomposition rate was 4.5%.

[0040] Implementation Three

[0041] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.02g of formic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 85%, and its relative decomposition rate was 5.6%.

[0042] Example 4

[0043] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.02g of acetic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 87%, and its relative decomposition rate was 3.3%.

[0044] Example 5

[0045] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.01g of acetic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 86%, and its relative decomposition rate was 4.5%.

[0046] Example 6

[0047] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.03g of acetic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 88%, and its relative decomposition rate was 2.2%.

[0048] Example 7

[0049] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.045g of acetic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 89%, and its relative decomposition rate was 1.1%.

[0050] Example 8

[0051] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.06g of acetic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 88%, and its relative decomposition rate was 2.2%.

[0052] Example 9

[0053] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.08g of acetic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 87%, and its relative decomposition rate was 3.3%.

[0054] Example 10

[0055] Take 10.00g of triazophos technical with a mass concentration of 90%, add 0.1g of acetic acid, stir until evenly mixed, place in an ampoule and seal, then place in a constant temperature oven at 54℃±2℃, store for 14 days, and take it out. The content of triazophos technical was determined to be 86%, and its relative decomposition rate was 4.5%.

[0056] Compared with the comparative examples, Examples 1 to 10 significantly reduced the thermal decomposition rate of triazophos by adding trace amounts of weakly acidic organic matter.

[0057] Comparing Examples 1 to 4, it can be seen that using acetic acid as a stabilizer has a more prominent stabilizing effect on triazophos.

[0058] Comparing Examples 4 to 10, it can be seen that when the mass ratio of triazophos technical to acetic acid is 100:0.45, acetic acid has the best stabilizing effect on triazophos.

[0059] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent substitutions, improvements, etc., made within the spirit and principles of the present invention should be included within the protection scope of the present invention.

Claims

1. A triazophos pesticide, characterized in that: It includes triazophos technical and a stabilizer, wherein the mass ratio of the triazophos technical to the stabilizer is 100:0.1 to 1, and the stabilizer is a weakly acidic organic compound.

2. The triazophos pesticide as described in claim 1, characterized in that: The mass ratio of the triazophos technical grade to the stabilizer is 100:0.3-0.

6.

3. The triazophos pesticide as described in claim 1, characterized in that: The weakly acidic organic compound is any one of formic acid, acetic acid, propionic acid, and butyric acid.

4. The triazophos pesticide as described in claim 3, characterized in that: The weakly acidic organic compound is acetic acid.

5. The triazophos pesticide as described in claim 4, characterized in that: The mass ratio of the triazophos technical grade to the acetic acid is 100:0.

45.

6. The triazophos pesticide as described in claim 1, characterized in that: The mass concentration of the triazophos technical grade is 90-95%.

7. A method for preparing the triazophos pesticide according to any one of claims 1-6, characterized in that: Add the stabilizer to the triazophos technical grade and stir until the mixture is homogeneous.

8. The preparation method according to claim 7, characterized in that: The mixing step is carried out in an environment isolated from moisture.

9. The use of the triazophos pesticide according to any one of claims 1-6 in the preparation of an insecticide for controlling pests of rice or cotton.

10. A triazophos pesticide composition, characterized in that: It comprises the triazophos pesticide according to any one of claims 1-6, and a pesticide-acceptable carrier and / or adjuvant.