A long-lasting mosquito repellent lacquer wood wax composite balm and a preparation method thereof

Abstract

This invention relates to the field of cosmetic products, specifically disclosing a long-lasting mosquito-repellent lacquerwood wax composite balm. This composite balm, by weight fraction, comprises 20-25 parts by weight of lacquerwood peel wax, 12-18 parts by weight of lemon eucalyptus oil, 3-8 parts by weight of catnip oil, 35-45 parts by weight of a temperature-controlled phase change regulating oil, 5-10 parts by weight of a hydrophobic plant-derived film-forming agent, 2-5 parts by weight of isosorbide dicaprylate, and 0.5-1 part by weight of a fat-soluble antioxidant. The long-lasting mosquito-repellent lacquerwood wax composite balm of this invention achieves a long-lasting and stable release of mosquito-repellent active ingredients, while also possessing suitable temperature-controlled phase change properties, a pleasant skin feel, synergistic mosquito-repellent effects, excellent hydrophobic and sweat-resistant capabilities, and stable storage of natural components.

Description

Technical Field

[0001] This invention relates to the field of cosmetic products, and more particularly to a long-lasting mosquito-repellent lacquerwood wax composite balm and its preparation method. Background Technology

[0002] Mosquito repellents, as an important component of personal protective equipment, play an irreplaceable role in preventing the spread of mosquito-borne infectious diseases such as dengue fever and malaria, and in improving the outdoor living experience. Currently, commercially available mosquito repellents are mainly divided into chemically synthesized and natural plant-derived types. Chemically synthesized mosquito repellents, represented by DEET and IR3535, have certain advantages in terms of mosquito-repelling efficacy and duration of protection. However, as consumers increasingly demand products with natural safety, biocompatibility, and environmental friendliness, the market demand for natural plant-derived mosquito repellent raw materials and formulations is gradually increasing.

[0003] However, existing natural plant-based mosquito repellents still have many inherent technical defects in practical applications, which restrict the user experience and protective performance of the products. These defects are specifically reflected in the following aspects:

[0004] First, natural plant-based mosquito repellent essential oils generally suffer from a short duration of protection. The active ingredients in plants with mosquito-repellent properties are mostly monoterpenes and sesquiterpenes, which have small molecular weights, high saturated vapor pressures, and are inherently volatile. Under the combined effects of high ambient temperatures and human body surface temperatures in summer, the active ingredients tend to evaporate rapidly within a short period, exhibiting a non-stable release characteristic: initially, the release concentration is too high and the odor is strong, but later the effective concentration quickly falls below the mosquito-repellent threshold, resulting in ineffectiveness. Existing conventional methods for extending the duration of effectiveness, such as encapsulation, mineral adsorption, and polymer film formation, generally suffer from complex preparation processes, the risk of solvent residue, or the contradiction of excessively binding the active ingredients, leading to a decrease in repellency efficiency. It is difficult to simultaneously achieve long-lasting controlled release and high mosquito-repellent activity.

[0005] Secondly, existing natural mosquito repellents struggle to simultaneously achieve a suitable physical form and a pleasant skin feel. Most current natural mosquito repellent products on the market are sprays or lotions. These formulations have weak film-forming ability and poor resistance to sweat rinsing, easily fading with sweat or rubbing off in sweaty or outdoor environments, resulting in insufficient protective stability. Traditional paste-like mosquito repellent carriers often use high-melting-point mineral waxes or ordinary beeswax as the matrix. The melting temperature of these matrices is far higher than human body temperature, resulting in a hard texture, poor spreadability, a sticky feel, poor breathability, and difficulty in forming a uniform and continuous protective film on the skin, leading to uneven distribution of the repellent ingredients and creating blind spots in protection.

[0006] Furthermore, existing mosquito repellent substrates generally lack the ability to regulate phase change in response to temperature. Mosquitoes primarily rely on carbon dioxide released by the human body, body heat, and volatile metabolites such as lactic acid and ammonia for location tracking. The risk of mosquito bites is higher in high-temperature environments or when the human body is sweating due to exercise, which correspondingly increases the requirements for the timeliness and intensity of mosquito repellent protection. However, the release of active ingredients in existing conventional mosquito repellent substrates mainly relies on concentration gradient diffusion, which cannot adaptively regulate with changes in human body surface temperature. It also cannot match the release rate according to actual protection needs, resulting in poor temperature control adaptability.

[0007] Furthermore, the chemical stability of natural plant-derived active ingredients is insufficient. Terpenes, aldehydes, and other plant-based mosquito-repellent components are highly sensitive to light, oxygen, and temperature, and are prone to oxidation, dehydrogenation, polymerization, and deterioration during storage and use, leading to problems such as darkening of color, development of odors, and decreased mosquito-repellent activity. In multi-component compound systems, how to constrain the molecular movement of volatile and easily oxidized components through matrix structure compatibility and intermolecular interactions to improve the overall physicochemical stability and shelf-life efficacy consistency is a technical challenge that current technologies struggle to adequately address.

[0008] Finally, existing natural mosquito repellent creams generally lack excellent surface hydrophobic protection mechanisms. Human sweat secretion not only accelerates the emulsification and loss of the oily matrix but also alters the distribution and volatilization kinetics of active ingredients at the skin interface, easily causing a rapid decline in mosquito repellent efficacy. Currently, there is a lack of mosquito repellent cream systems that simultaneously meet the requirements of being entirely plant-based, forming a stable hydrophobic protective film on the skin surface, and being suitable for complex scenarios involving high humidity and excessive sweating. This limits the product's environmental resistance and practical applicability.

[0009] In summary, existing natural plant-based mosquito repellents generally suffer from several technical shortcomings, including uncontrollable release of active ingredients, short duration of protection, poor skin feel, lack of temperature-responsiveness, easy oxidation and inactivation of active components, and weak resistance to sweat and environmental interference. These limitations make it difficult to simultaneously meet the application requirements of long-lasting mosquito repellency, comfortable use, stable physicochemical properties, and adaptability to various scenarios. Therefore, developing a plant-based composite mosquito repellent balm with a rationally formulated structure, capable of stable and long-lasting release of active ingredients, possessing suitable temperature-controlled phase change characteristics, a pleasant skin feel, high chemical stability, and hydrophobic and sweat-resistant properties is a pressing technical challenge in this field. Summary of the Invention

[0010] Based on this, the purpose of the present invention is to provide a long-lasting mosquito-repellent lacquer tree wax composite balm that can achieve long-term and stable release of mosquito-repellent active ingredients, and has suitable temperature control phase change performance, good skin feel, synergistic mosquito-repellent effect, excellent hydrophobic and sweat-resistant ability and storage stability of natural components.

[0011] The long-lasting mosquito-repellent lacquerwood wax composite balm of this invention is achieved through the following technical solution: A long-lasting mosquito-repellent lacquer tree wax compound balm, characterized in that, by mass fraction, it comprises: 20-25 parts by mass of lacquer fruit peel wax, 12-18 parts by mass of lemon eucalyptus leaf oil, 3-8 parts by mass of catnip oil, 35-45 parts by mass of temperature-controlled phase change regulating oil, 5-10 parts by mass of hydrophobic plant-derived film-forming agent, 2-5 parts by mass of isosorbide dicaprylate, and 0.5-1 parts by mass of fat-soluble antioxidant.

[0012] Compared to existing technologies, this invention effectively solves the technical problems of short-lasting mosquito repellent effect, poor sweat resistance, unstable physical properties, and easy volatility and inactivation of active ingredients in existing natural mosquito repellent balms through the scientific compatibility and synergistic effect of various functional components. The composite balm of this invention uses lacquer fruit peel wax as the core matrix, synergistically constructing a physical encapsulation matrix and hydrophobic barrier with a hydrophobic plant-derived film-forming agent, achieving efficient encapsulation of active ingredients and reducing sweat erosion; temperature-controlled phase change regulation modulates the phase change characteristics of the balm, balancing storage stability and skin feel; lemon eucalyptus oil and catnip oil synergistically form a dual-target mosquito repellent system, enhancing mosquito repellent efficacy; isosorbide dicaprylate enables long-term controlled release of active ingredients, and lipid-soluble antioxidants inhibit the oxidation of terpenoid components, ensuring storage stability. The synergistic effect of each component makes the composite balm superior to existing technologies in overall performance, and the raw materials are natural, highly safe, and have good industrial applicability.

[0013] Furthermore, the temperature-controlled phase change regulating oil is a natural plant oil that exhibits solid-liquid phase change characteristics within the range of 20°C to 30°C. By limiting the phase change temperature range of the temperature-controlled phase change regulating oil, it can be adapted to both room temperature storage and human body surface temperature, balancing the stability of the balm during room temperature storage with its skin-feeling properties, avoiding unnecessary loss of active ingredients, and improving upon the shortcomings of traditional wax-based balms.

[0014] Furthermore, the temperature-controlled phase change regulating oil is coconut oil or mango seed oil. The selection of coconut oil or mango seed oil satisfies the requirements for suitable phase change characteristics, has good compatibility with all components of the system, is natural, safe, and non-irritating, and can also help optimize the skin feel of the balm.

[0015] Furthermore, the hydrophobic plant-derived film-forming agent has a static contact angle greater than 90° at 25°C and can co-melt with the lacquer fruit peel wax to form a continuous hydrophobic barrier. By defining the characteristics of the hydrophobic plant-derived film-forming agent, it can synergistically form a hydrophobic protective film with the lacquer fruit peel wax, improving the product's resistance to sweat and high humidity, avoiding blind spots in protection, and solving the problem of diminished protective effect in sweaty environments.

[0016] Furthermore, the hydrophobic plant-derived film-forming agent is hydrogenated soybean oil glycerides or glycerol rod oil esters. The selection of hydrogenated soybean oil glycerides or glycerol rod oil esters meets the requirements for hydrophobic film formation, exhibits good eutectic properties with the system components, is natural and safe, and balances hydrophobic protection with operational stability.

[0017] Furthermore, the lipid-soluble antioxidant can inhibit the oxidative dehydrogenation of terpenoids. By limiting the function of the lipid-soluble antioxidant, the active ingredients of terpenoids can be specifically protected, preventing their oxidative inactivation, extending the shelf life of the balm, and ensuring consistent efficacy.

[0018] Furthermore, the lipid-soluble antioxidant is tocopherol or tocopherol acetate. Tocopherol or tocopherol acetate is chosen because it has good lipid solubility and compatibility, can effectively inhibit terpene oxidation, is safe and non-irritating, and is widely available and easy to produce industrially.

[0019] The present invention also provides a method for preparing the above-mentioned long-lasting mosquito-repellent lacquerwood wax composite balm, comprising the following steps: S1: Mix lacquer fruit peel wax, temperature-controlled phase change regulating oil and hydrophobic plant-derived film-forming agent evenly, heat until completely melted, and obtain oil phase matrix; S2: Cool the oil phase matrix obtained in step S1, and add isosorbide dioctanoate, lemon eucalyptus oil, catnip oil and fat-soluble antioxidants under stirring conditions, and mix well; S3: Fill the container while hot, and after cooling, you will get the lacquerwood wax composite perfume.

[0020] The preparation method is simple and convenient to operate, making it easy for industrial production. The steps are reasonably designed to avoid high-temperature loss of active ingredients, ensure the stability of the balm's performance, and improve the encapsulation effect and long-lasting controlled-release performance of active ingredients.

[0021] Furthermore, this invention also seeks to protect the use of the above-mentioned long-lasting mosquito-repellent lacquerwood wax composite balm in the preparation of mosquito-repellent products.

[0022] The present invention also provides a mosquito repellent product, comprising the above-mentioned long-lasting mosquito repellent lacquerwood wax compound balm. Detailed Implementation

[0023] To better understand the present invention, the present invention will be further described below with reference to specific serial numbers. The terminology used in the serial numbers is for describing specific embodiments and does not constitute a limitation on the scope of protection of the present invention.

[0024] In the specific implementation methods, unless otherwise specified, the experimental methods used are all conventional methods, and the materials and reagents used are all commercially available unless otherwise specified.

[0025] In this invention, the lacquer tree wax refers to the wax of lacquer (RHUSVERNICIFLUA) fruit peel.

[0026] In this invention, lemon eucalyptus leaf oil refers to lemon eucalyptus (EUCALYPTUSCITRIODORA) leaf oil.

[0027] In the present invention, catnip oil refers to the oil of Nepeta cataria; the official Chinese name of Nepeta cataria is Nepeta cataria.

[0028] In the present invention, schizonepeta oil refers to the oil of Schizonepeta tenuifolia; the official Chinese name of Schizonepeta tenuifolia is Schizonepeta tenuifolia.

[0029] Example 1 A long-lasting mosquito-repellent lacquer tree wax composite balm, by mass fraction, comprises 20 parts by mass of lacquer fruit wax, 12 parts by mass of lemon eucalyptus oil, 3 parts by mass of catnip oil, 35 parts by mass of coconut oil, 5 parts by mass of hydrogenated soybean oil glycerides, 2 parts by mass of isosorbide dicaprylate and 0.5 part by mass of tocopherol.

[0030] The lacquer tree wax composite balm of this example is prepared by the following preparation method: S1 Preparation of oil phase: Add lacquer fruit wax, coconut oil, and hydrogenated soybean oil glycerides to a stainless steel reaction kettle, heat to 75 °C, and continuously stir until all components are completely melted to form a uniform and transparent oil phase matrix.

[0031] S2 Mixing of active components: Cool the oil phase matrix obtained in step S! to 52 °C, and sequentially add isosorbide dicaprylate, lemon eucalyptus oil, catnip oil, and tocopherol under stirring at 200 rpm, and continue to stir for 10 minutes to make them evenly mixed.

[0032] S3 Filling and curing: Keep it at 50 °C and fill it into a container while it is hot, and then place it in a 5 °C cooling tunnel to quickly cool for 15 minutes, so that the lacquer fruit wax quickly precipitates dense microcrystals to form a balm with a flat surface.

[0033] Example 2 A long-lasting mosquito-repellent lacquer tree wax composite balm, different from Example 1 in that the mass fractions of each component are different. The lacquer tree wax composite balm of this example, by mass fraction, comprises 23 parts by mass of lacquer fruit wax, 16 parts by mass of lemon eucalyptus oil, 5.5 parts by mass of catnip oil, 45 parts by mass of coconut oil, 6 parts by mass of hydrogenated soybean oil glycerides, 3 parts by mass of isosorbide dicaprylate and 0.5 part by mass of tocopherol.

[0034] The preparation method of the lacquer tree wax composite balm of this example is the same as that of Example 1.

[0035] Example 3 A long-lasting mosquito-repellent lacquer tree wax compound balm, comprising, by weight, 25 parts lacquer fruit peel wax, 18 parts lemon eucalyptus oil, 8 parts catnip oil, 45 parts mango seed oil, 10 parts glyceryl rosinate, 5 parts isosorbide dicaprylate and 1 part tocopheryl acetate.

[0036] S1 oil phase preparation: Add lacquer fruit peel wax, mango seed oil, and glycerol rosinate to a stainless steel reactor, heat to 75°C, and stir continuously until all components are completely melted to form a uniform and transparent oil phase matrix.

[0037] S2 Active Component Mixing: Cool the oil phase matrix obtained in step S1 to 52°C, and add isosorbide dioctanoate, lemon eucalyptus oil, catnip oil and tocopheryl acetate in sequence under stirring at 200 rpm, and continue stirring for 10 minutes to mix evenly.

[0038] S3 Filling and Curing: Fill the container while it is still hot at 50℃, then place it in a 5℃ cooling tunnel for rapid cooling for 15 minutes to allow the lacquer peel wax to quickly precipitate into dense microcrystals, forming a smooth balm.

[0039] Comparative Example 1 A long-lasting mosquito-repellent compound balm, differing from Example 1 in that this comparative compound balm does not contain catnip oil; this comparative compound balm comprises, by weight, 20 parts of lacquer fruit peel wax, 15 parts of lemon eucalyptus oil, 35 parts of coconut oil, 5 parts of hydrogenated soybean oil glycerides, 2 parts of isosorbide dicaprylate and 0.5 parts of tocopherol.

[0040] The above-mentioned compound perfume balm is prepared by the following method: S1 oil phase preparation: Add lacquer fruit peel wax, coconut oil, and hydrogenated soybean oil glycerides to a stainless steel reactor, heat to 75°C, and stir continuously until all components are completely melted to form a uniform and transparent oil phase matrix.

[0041] S2 Active Component Mixing: Cool the oil phase matrix obtained in step S1 to 52°C, and add isosorbide dioctanoate, lemon eucalyptus oil and tocopherol sequentially under stirring at 200 rpm, and continue stirring for 10 minutes to mix evenly.

[0042] S3 Filling and Curing: Fill the container while it is still hot at 50℃, then place it in a 5℃ cooling tunnel for rapid cooling for 15 minutes to allow the lacquer peel wax to quickly precipitate into dense microcrystals, forming a smooth balm.

[0043] Comparative Example 2 A long-lasting mosquito-repellent compound balm differs from Example 1 in that this comparative compound balm does not contain lemon eucalyptus oil; this comparative compound balm comprises, by weight parts, 20 parts of lacquer fruit peel wax, 15 parts of catnip oil, 35 parts of coconut oil, 5 parts of hydrogenated soybean oil glycerides, 2 parts of isosorbide dicaprylate and 0.5 parts of tocopherol.

[0044] The above-mentioned compound perfume balm is prepared by the following method: S1 oil phase preparation: Add lacquer fruit peel wax, coconut oil, and hydrogenated soybean oil glycerides to a stainless steel reactor, heat to 75°C, and stir continuously until all components are completely melted to form a uniform and transparent oil phase matrix.

[0045] S2 Active Component Mixing: Cool the oil phase matrix obtained in step S1 to 52°C, and add isosorbide dioctanoate, catnip oil and tocopherol sequentially under stirring at 200 rpm, and continue stirring for 10 minutes to mix evenly.

[0046] S3 Filling and Curing: Fill the container while it is still hot at 50℃, then place it in a 5℃ cooling tunnel for rapid cooling for 15 minutes to allow the lacquer peel wax to quickly precipitate into dense microcrystals, forming a smooth balm.

[0047] Comparative Example 3 A long-lasting mosquito-repellent compound balm differs from Example 1 in that this comparative compound balm uses catnip oil instead of the original lemon eucalyptus oil and catnip oil; this comparative compound balm comprises, by weight parts, 20 parts of lacquer fruit peel wax, 15 parts of catnip oil, 35 parts of coconut oil, 5 parts of hydrogenated soybean oil glycerides, 2 parts of isosorbide dicaprylate and 0.5 parts of tocopherol.

[0048] The above-mentioned compound perfume balm is prepared by the following method: S1 oil phase preparation: Add lacquer fruit peel wax, coconut oil, and hydrogenated soybean oil glycerides to a stainless steel reactor, heat to 75°C, and stir continuously until all components are completely melted to form a uniform and transparent oil phase matrix.

[0049] S2 Active Component Mixing: Cool the oil phase matrix obtained in step S1 to 52°C, and add isosorbide dioctanoate, catnip oil and tocopherol sequentially under stirring at 200 rpm, and continue stirring for 10 minutes to mix evenly.

[0050] S3 Filling and Curing: Fill the container while it is still hot at 50℃, then place it in a 5℃ cooling tunnel for rapid cooling for 15 minutes to allow the lacquer peel wax to quickly precipitate into dense microcrystals, forming a smooth balm.

[0051] Comparative Example 4 A long-lasting mosquito-repellent compound balm differs from Example 1 in that this comparative compound balm does not contain hydrogenated soybean oil glycerides; this comparative compound balm comprises, by weight, 20 parts of lacquer fruit peel wax, 12 parts of lemon eucalyptus oil, 3 parts of catnip oil, 40 parts of coconut oil, 2 parts of isosorbide dicaprylate and 0.5 parts of tocopherol.

[0052] The above-mentioned compound perfume balm is prepared by the following method: S1 oil phase preparation: Add lacquer fruit peel wax and coconut oil to a stainless steel reactor, heat to 75°C, and continue stirring until all components are completely melted to form a uniform and transparent oil phase matrix.

[0053] S2 Active Component Mixing: Cool the oil phase matrix obtained in step S1 to 52°C, and add isosorbide dioctanoate, lemon eucalyptus oil, catnip oil and tocopherol sequentially under stirring at 200 rpm, and continue stirring for 10 minutes to mix evenly.

[0054] S3 Filling and Curing: Fill the container while it is still hot at 50℃, then place it in a 5℃ cooling tunnel for rapid cooling for 15 minutes to allow the lacquer peel wax to quickly precipitate into dense microcrystals, forming a smooth balm.

[0055] Comparative Example 5 A long-lasting mosquito-repellent compound balm differs from Example 1 in that this comparative compound balm does not contain lacquer fruit peel wax or hydrogenated soybean oil glycerides; this comparative compound balm comprises, by weight, 12 parts lemon eucalyptus oil, 3 parts catnip oil, 60 parts coconut oil, 2 parts isosorbide dicaprylate and 0.5 parts tocopherol.

[0056] The above-mentioned compound perfume balm is prepared by the following method: S1 oil phase preparation: Coconut oil is added to a stainless steel reactor, heated to 75°C, and continuously stirred until all components are completely melted to form a uniform and transparent oil phase matrix.

[0057] S2 Active Component Mixing: Cool the oil phase matrix obtained in step S1 to 52°C, and add isosorbide dioctanoate, lemon eucalyptus oil, catnip oil and tocopherol sequentially under stirring at 200 rpm, and continue stirring for 10 minutes to mix evenly.

[0058] S3 Filling and Curing: Fill the container while it is still hot at 50°C, then place it in a 5°C cooling tunnel for rapid cooling for 15 minutes to obtain the perfume balm.

[0059] Comparative Example 6 A long-lasting mosquito-repellent compound balm differs from Example 1 in that beeswax is used instead of lacquer fruit peel wax in this comparative compound balm. This comparative compound balm comprises, by weight, 20 parts beeswax, 12 parts lemon eucalyptus oil, 3 parts catnip oil, 35 parts coconut oil, 5 parts hydrogenated soybean oil glycerides, 2 parts isosorbide dicaprylate, and 0.5 parts tocopherol.

[0060] The above-mentioned lacquerwood wax composite perfume is prepared by the following method: S1 oil phase preparation: Beeswax, coconut oil, and hydrogenated soybean oil glycerides are added to a stainless steel reactor, heated to 75°C, and continuously stirred until all components are completely melted to form a uniform and transparent oil phase matrix.

[0061] S2 Active Component Mixing: Cool the oil phase matrix obtained in step S1 to 52°C, and add isosorbide dioctanoate, lemon eucalyptus oil, catnip oil and tocopherol sequentially under stirring at 200 rpm, and continue stirring for 10 minutes to mix evenly.

[0062] S3 Filling and Curing: Fill the container while it is still hot at 50℃, then place it in a 5℃ cooling tunnel for rapid cooling for 15 minutes to allow the beeswax to quickly precipitate into dense microcrystals, forming a smooth balm.

[0063] Comparative Example 7 A long-lasting mosquito-repellent lacquerwood wax compound balm, differing from Example 1 in that this comparative compound balm does not contain isosorbide dicaprylate; this comparative compound balm comprises, by weight parts, 20 parts of lacquerwood peel wax, 12 parts of lemon eucalyptus oil, 3 parts of catnip oil, 37 parts of coconut oil, 5 parts of hydrogenated soybean oil glycerides, and 0.5 parts of tocopherol.

[0064] The above-mentioned lacquerwood wax composite perfume is prepared by the following method: S1 oil phase preparation: Add lacquer fruit peel wax, coconut oil, and hydrogenated soybean oil glycerides to a stainless steel reactor, heat to 75°C, and stir continuously until all components are completely melted to form a uniform and transparent oil phase matrix.

[0065] S2 Active Component Mixing: Cool the oil phase matrix obtained in step S1 to 52°C, and add lemon eucalyptus oil, catnip oil and tocopherol sequentially under stirring at 200 rpm, and continue stirring for 10 minutes to mix evenly.

[0066] S3 Filling and Curing: Fill the container while it is still hot at 50℃, then place it in a 5℃ cooling tunnel for rapid cooling for 15 minutes to allow the lacquer peel wax to quickly precipitate into dense microcrystals, forming a smooth balm.

[0067] Performance testing 1. Test subjects: Compound perfumes of Examples 1-3 and Comparative Examples 1-7.

[0068] 2. Testing Method: The static contact angle of each composite fragrance was tested according to GB / T30693-2014 "Surface Chemical Contact Angle Measurement Method" to verify the film-forming hydrophobicity. The effective protective time of each compound balm was tested in accordance with GB / T13917.9-2009 "Field Efficacy Determination and Evaluation of Sanitary Insecticides - Part 9: Repellents". Referring to the test methods in GB / T13917.9-2009 "Field Efficacy Determination and Evaluation of Sanitary Insecticides - Part 9: Repellents", and according to the formula: mosquito repellency rate (%) = (CT) / C × 100%, the 4-hour mosquito repellency rate of each compound balm was calculated. Wherein C (control group): refers to the number of mosquito bites (or landings) in the skin area without any mosquito repellent product within a specified time; T (test area): refers to the number of mosquito bites (or landings) in the skin area with mosquito repellent product within the same time period. The phase transition temperatures of each compound fragrance were determined in accordance with GB / T19466.3-2004 "Differential Scanning Calorimetry (DSC) for Plastics - Part 3: Determination of Melting and Crystallization Temperatures and Enthalpy".

[0069] 3. Test results: as shown in Table 1 below.

[0070] Table 1. Performance test results of compound perfumes in Examples 1-3 and Comparative Examples 1-7

[0071] According to the test results in Table 1, the composite balms of Examples 1-3 of this invention exhibit stable performance in terms of static contact angle, effective protection time, 4-hour mosquito repellency rate, and phase transition temperature range. Among these, the three core indicators—static contact angle, effective protection time, and 4-hour mosquito repellency rate—are superior to those of the comparative groups, demonstrating the scientific and rational formulation of this invention. By comparing the test data of Example 1 with those of the comparative groups, the functional roles of each component in the composite balm and the synergistic effects between components can be clearly identified, as detailed below: The composite balms of Comparative Examples 1 and 2, lacking the catnip oil and lemon eucalyptus oil of Example 1, showed a significant decrease in their mosquito-repellent properties (effective protection time and 4-hour mosquito repellency rate). Specifically, Comparative Example 1 had an effective protection time of 4.2 hours and a 4-hour mosquito repellency rate of 75.6%, while Comparative Example 2 had an effective protection time of 3.5 hours and a 4-hour mosquito repellency rate of 62.4%, both lower than the 6.8 hours and 98.5% of Example 1. This is because the catnip oil and lemon eucalyptus oil in the composite balm of this invention can synergistically form a dual mosquito-repellent defense system: lemon eucalyptus oil, through its volatile components, constructs an olfactory shielding layer on the skin surface, interfering with mosquitoes' sensing of human chemotactic signals; nepetalactone in catnip oil can specifically activate mosquito avoidance receptors, achieving mosquito repulsion. The synergistic effect of the two ensures the mosquito-repellent effect of the composite balm. Comparative Examples 1 and 2, lacking one of the essential oils respectively, could not construct a complete dual mosquito repellent defense system and could only achieve a single-mode mosquito repellent effect. Therefore, their mosquito repellent performance was significantly inferior to that of Example 1.

[0072] Comparative Example 3, using catnip oil instead of catnip and lemon eucalyptus oil in Example 1, showed a further decrease in repellency compared to Comparative Examples 1 and 2, with an effective protection time of only 2.1 hours and a 4-hour mosquito repellency rate of only 45%. The main active ingredients of the catnip oil used in Comparative Example 3 are pulegone, nepetaside, and menthone. These substances can interfere with mosquitoes' perception of human sweat odors (lactic acid, ammonia, etc.) through their own scent, thus achieving a certain mosquito-repelling effect. However, these active substances are highly volatile and evaporate rapidly after application, leading to a decrease in the concentration of effective ingredients on the skin surface and preventing sustained mosquito-repelling action. Therefore, the repellency of Comparative Example 3, due to the rapid decay of active substances, cannot achieve the protective durability of the composite balm in Example 1.

[0073] The compound balm in Comparative Example 4 lacked the hydrogenated soybean oil glycerides (hydrophobic plant-derived film-forming agents) found in Example 1. This component's function is to form a continuous, hydrophobic film on the skin surface after the balm liquefies. Table 1 shows that the static contact angle of Comparative Example 4 was only 72.3°, significantly lower than the 98.6° of Example 1. This weakened its resistance to sweat rinsing, resulting in a reduction in effective protection time to 3.8 hours and a 4-hour mosquito repellency rate to 68.2%. These results indicate that sweat rinsing and emulsification are significant environmental factors leading to the loss of effective components in natural essential oil preparations and the loss of mosquito-repellent effects. The addition of hydrogenated soybean oil glycerides can effectively improve the balm's anti-sweat properties and ensure the stability of its mosquito-repellent effect.

[0074] Compared to Comparative Example 4, Comparative Example 5's composite balm further lacked lacquer fruit peel wax, resulting in significant deterioration in all its properties: the static contact angle decreased to 65.4°, the effective protection time was only 1.5 hours, the 4-hour mosquito repellency rate was 32.5%, the phase transition temperature range shifted to 22.0~24.8℃, and the physical stability decreased. These results indicate that lacquer fruit peel wax is fundamental to maintaining the physical structural stability and controlled-release function of the composite balm of this invention. It can synergistically enhance the film-forming hydrophobicity of the balm with hydrogenated soybean oil glycerides, while simultaneously constructing a microcrystalline structure to achieve physical anchoring and slow controlled release of the mosquito-repellent active ingredients, ensuring the overall performance of the balm.

[0075] Comparative Example 6 used beeswax instead of the lacquer fruit peel wax in Example 1. Its static contact angle was 82.1° and its effective protection time was 4.8 hours, both of which were lower than those of Example 1. This is because the microcrystalline structure arrangement of lacquer fruit peel wax and beeswax differs. The microcrystalline network structure formed by beeswax is less dense and stable than that of lacquer fruit peel wax, resulting in a weaker physical locking ability and sustained-release effect for the mosquito-repellent active ingredients. This, in turn, reduces the hydrophobicity of the balm and accelerates the evaporation rate of the mosquito-repellent active ingredients, ultimately leading to a lower static contact angle and effective protection time than in Example 1. Furthermore, the phase transition temperature of Comparative Example 6 was increased to 35.5-42.0℃, exceeding the normal human body surface temperature range. The matrix could not achieve a smooth, stable liquid-phase transition using body surface temperature, failing to achieve the instant-melting spreading effect upon contact with the skin. The balm texture was harder, resulting in poorer application uniformity, a sticky feel, and reduced breathability. It also disrupted the original temperature control compatibility of the composite system, further weakening the actual user experience and outdoor suitability of the product.

[0076] Compared to Example 1, the composite balm in Comparative Example 7 lacked isosorbide dicaprylate, resulting in a 4-hour mosquito repellency rate of 80.2% and a correspondingly shorter effective protection time. This result indicates that isosorbide dicaprylate can form intermolecular interactions with the balm matrix components, thereby regulating the saturated vapor pressure of the mosquito-repellent active ingredients and slowing their volatilization rate, thus extending the effective mosquito-repellent duration of the balm. It is an important auxiliary component in the composite balm of this invention for achieving long-lasting mosquito repellency.

[0077] Compared to existing technologies, this invention, through the scientific compatibility and synergistic effect of its functional components, constructs a composite balm system that combines mosquito-repellent efficacy, controlled-release performance, usage stability, and storage stability. This effectively solves the technical problems of existing natural mosquito-repellent balms, such as short mosquito-repellent duration, poor sweat resistance, unstable physical properties, and easy volatilization and inactivation of active ingredients. The synergistic effect principle and technical advantages of its components are as follows: This invention uses lacquer fruit peel wax as the core matrix component. Its unique triglyceride microcrystalline network structure can synergistically interact with hydrophobic plant-derived film-forming agents (hydrogenated soybean oil glycerides or glycerol rosinate): on the one hand, the two work together to construct a dense physical encapsulation matrix, achieving efficient encapsulation and physical anchoring of volatile mosquito-repellent active ingredients such as lemon eucalyptus oil and catnip oil; on the other hand, the two work together to form a continuous hydrophobic film-forming system, improving the hydrophobicity of the balm after film formation and reducing the emulsification and loss of active ingredients by skin sweat. Simultaneously, by introducing a specific proportion of temperature-controlled phase change regulating oils (coconut oil or mango seed oil), which synergistically regulate the melting range of the composite matrix with lacquer fruit peel wax and hydrophobic plant-derived film-forming agents, the three form a composite matrix system with excellent compatibility. This system can remain stable in a solid state under normal temperature storage conditions, effectively avoiding oil leakage and unnecessary loss of active ingredients. Once in contact with human skin, the temperature-controlled phase change regulating oils can quickly absorb heat to trigger a solid-liquid phase change in the matrix, causing the lacquer fruit peel wax and hydrophobic plant-derived film-forming agents to liquefy simultaneously, achieving an instant "melt-on-skin" spreading effect. This synergistic phase change characteristic not only ensures the uniformity of application but also effectively overcomes the technical defects of traditional wax-based balms, such as hard texture, stickiness, and poor breathability, while providing stable matrix support for hydrophobic film formation and controlled release of active ingredients.

[0078] Lemon eucalyptus oil and catnip oil are synergistic mosquito-repellent components. Their mechanisms of action are complementary, forming a dual-target mosquito-repellent system: lemon eucalyptus oil forms an olfactory shielding layer on the skin surface through its volatile components, interfering with mosquitoes' recognition and sensing of human chemotactic signals; catnip oil contains nepetalactone, which can specifically activate mosquitoes' avoidance receptors, enabling mosquitoes to avoid it. The synergistic effect of the two not only improves the mosquito-repellent efficacy but also reduces the amount of each single component required, while broadening the protective compatibility with different mosquito species.

[0079] Isosorbide dicaprylate, as a sustained-release and stabilizing auxiliary component, forms intermolecular interactions with the lacquer fruit wax microcrystalline matrix. By regulating the saturated vapor pressure of the mosquito-repellent active ingredient, it slows down the volatilization rate of the active ingredient, achieving a long-lasting and stable controlled release of the active ingredient and extending the effective protection time of the balm. At the same time, it works synergistically with fat-soluble antioxidants (tocopherol or tocopheryl acetate) to inhibit the oxidative dehydrogenation reaction of terpenoids in natural essential oils, preventing the inactivation of active ingredients, product discoloration, and off-odors, and ensuring the consistency of efficacy and chemical stability of the balm during long-term storage.

[0080] In summary, the components in this invention are not simply superimposed, but form an organic whole that supports each other and enhances their synergistic effect. The synergistic effect of the components makes the composite balm of this invention superior to the prior art in terms of long-lasting mosquito repellency, resistance to environmental interference, physical property stability and chemical stability. Moreover, the raw materials are all from natural sources, have high safety, and have good industrial applicability.

[0081] The embodiments described above are merely examples of several implementations of the present invention, and while the descriptions are relatively specific and detailed, they should not be construed as limiting the scope of the invention. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and the present invention also intends to include these modifications and variations.

Claims

1. A long-lasting mosquito-repellent lacquerwood wax composite balm, characterized in that, By weight fraction, it includes: 20-25 parts by weight of lacquer fruit peel wax, 12-18 parts by weight of lemon eucalyptus oil, 3-8 parts by weight of catnip oil, 35-45 parts by weight of temperature-controlled phase change regulating oil, 5-10 parts by weight of hydrophobic plant-derived film-forming agent, 2-5 parts by weight of isosorbide dicaprylate, and 0.5-1 parts by weight of fat-soluble antioxidant.

2. The long-lasting mosquito-repellent lacquerwood wax composite balm according to claim 1, characterized in that: The temperature-controlled phase change regulating oil is a natural plant oil that has solid-liquid phase change characteristics within the range of 20℃ to 30℃.

3. The long-lasting mosquito-repellent lacquerwood wax composite balm according to claim 2, characterized in that: The temperature-controlled phase change regulating oil is coconut oil or mango seed oil.

4. The long-lasting mosquito-repellent lacquerwood wax composite balm according to claim 1, characterized in that: The hydrophobic plant-derived film-forming agent has a static contact angle greater than 90° at 25°C and can co-melt with the lacquer fruit peel wax to form a continuous hydrophobic barrier.

5. The long-lasting mosquito-repellent lacquerwood wax composite balm according to claim 4, characterized in that: The hydrophobic plant-derived film-forming agent is a hydrogenated soybean oil glyceride or a glycerol rosinate.

6. The long-lasting mosquito-repellent lacquerwood wax composite balm according to claim 1, characterized in that: The fat-soluble antioxidant can inhibit the oxidative dehydrogenation of terpenoids.

7. The long-lasting mosquito-repellent lacquerwood wax composite balm according to claim 6, characterized in that: The fat-soluble antioxidant is tocopherol or tocopherol acetate.

8. The method for preparing the long-lasting mosquito-repellent lacquerwood wax composite balm according to any one of claims 1 to 7, characterized in that, Includes the following steps: S1: Mix lacquer fruit peel wax, temperature-controlled phase change regulating oil and hydrophobic plant-derived film-forming agent evenly, heat until completely melted, and obtain oil phase matrix; S2: Cool the oil phase matrix obtained in step S1, and add isosorbide dioctanoate, lemon eucalyptus oil, catnip oil and fat-soluble antioxidants under stirring conditions, and mix well; S3: Fill the container while hot, and after cooling, you will get the lacquerwood wax composite perfume.

9. The use of the long-lasting mosquito-repellent lacquerwood wax compound balm according to any one of claims 1 to 7 in the preparation of mosquito-repellent products.

10. A mosquito repellent product, characterized in that: The lacquerwood wax compound balm with long-lasting mosquito repellency as described in any one of claims 1 to 7.

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