A plasma collection device for clinical medicine

By designing a plasma collection device that includes a mixer, a sentinel observation chamber, and electronic monitoring components, the problems of inaccurate metering and poor personalization adaptability of existing devices are solved. This device achieves uniform mixing, precise separation, and automated control of plasma, thereby improving the quality and safety of plasma collection.

CN122140250APending Publication Date: 2026-06-05TONGJI HOSPITAL ATTACHED TO TONGJI MEDICAL COLLEGE HUAZHONG SCI TECH
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Patent Information

Application Number
CN202610362062.X
Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-03-24
Publication Date
2026-06-05

AI Technical Summary

Technical Problem

Existing clinical plasma collection devices suffer from insufficient accuracy in measurement, poor personalization adaptability, and shortcomings in blood component protection, leading to inaccurate plasma collection, resource waste, and increased risk of blood component damage.

Method used

A plasma collection device was designed, consisting of a blood collection device, a first blood collection pump, a plasma mixing bag, an anticoagulant storage device, a centrifugal pump, a second blood collection pump, and a plasma storage bag. It is equipped with a mixer, a sentinel observation chamber, an electric valve, and an electronic monitoring component to achieve uniform mixing of blood and anticoagulant, precise separation of plasma, and automated control.

Benefits of technology

It achieves uniform plasma mixing, precise separation, and automated control, avoiding damage to blood components, ensuring the purity and quality of plasma collection, adapting to the personalized needs of different patients, and improving the accuracy and controllability of the collection process.

✦ Generated by Eureka AI based on patent content.

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Abstract

The application discloses a plasma collecting device for clinical medicine, and belongs to the technical field of clinical medicine. The device is mainly composed of a blood sampling device, a blood sampling pump, a plasma mixing bag, a centrifugal pump, a plasma storage bag and the like, is provided with a mixing device, a sentinel observation cavity, an electric valve and an electronic monitoring assembly in a matched mode, and various components are sequentially connected through a sampling and delivery hose. All functional components are controlled by the electronic monitoring assembly. The device realizes uniform mixing of blood samples and anticoagulants and avoids damage to blood components through a special roller mixing device. The device separates plasma with the help of a centrifugal pump, discriminates plasma, controls on-off through the cooperation of the sentinel observation cavity, the electric valve and the electronic monitoring assembly, realizes precise liquid delivery through the blood sampling pump, and is controlled by the electronic monitoring assembly throughout the process. The device adopts disposable blood sampling related tools, guarantees medical health, realizes the automation, precision and safety of plasma collection as a whole, and is suitable for clinical individual collection requirements.
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Description

Technical Field

[0001] This invention relates to the field of clinical medical technology, and in particular to a plasma collection device for clinical medicine. Background Technology

[0002] With the rapid development of society and the advancement of science and technology, the medical environment has been improved. Clinical plasma testing can be divided into general plasma testing, laboratory testing for hemolytic anemia, bone marrow cytology testing, blood typing and crossmatching tests. It can detect hematological signs of common blood diseases. By extracting patients' blood through plasma collection equipment, it is beneficial to grasp the patients' physical condition in a timely manner, which greatly improves work efficiency and medical quality.

[0003] The shortcomings of existing clinical plasma collection devices:

[0004] (1) Insufficient accurate measurement capability: The existing plasma collection system cannot accurately distinguish the volume of pure plasma and anticoagulant in the collected material. It can only use the total collection volume as the basis for stopping, which may result in the actual pure plasma collection volume not reaching the upper limit of medical standards, or due to individual differences, the plasma collection ratio of some patients is too low (e.g., only 23%), resulting in waste of resources.

[0005] (2) Poor personalization: Most devices only set the collection volume based on body weight and do not take into account individual differences in hematocrit, basal metabolism, etc., resulting in large fluctuations in the plasma collection ratio of different patients (23%-29%), which may cause unnecessary blood load to donors with special physical conditions.

[0006] (3) Shortcomings in blood component protection: Some devices cause significant mechanical damage to blood components such as red blood cells and platelets during the plasma separation process, which reduces the quality of reinfused blood and increases the risk of adverse reactions such as hemolysis and thrombocytopenia in the donor. Summary of the Invention

[0007] The present invention aims to provide a plasma collection device for clinical medicine to solve the problems mentioned in the background art.

[0008] To achieve the above objectives, the present invention provides the following technical solution:

[0009] A plasma collection device for clinical medicine comprises a blood collection device, a first blood collection pump, a plasma mixing bag, an anticoagulant storage device, a centrifugal pump, a second blood collection pump, and a plasma storage bag;

[0010] The plasma mixing bag is equipped with a mixer, a sentinel observation chamber and an electric valve are provided between the centrifugal pump and the second blood collection pump, and the overall device is also equipped with an electronic monitoring component.

[0011] The device is formed by sequentially connecting a blood collection device, a first blood collection pump, a plasma mixing bag, an anticoagulant storage device, a centrifugal pump, a second blood collection pump, and a plasma storage bag via a blood collection and delivery hose. The electronic monitoring component can detect and control the operation of each component in real time. A sentinel observation chamber and an electric valve are provided between the centrifugal pump and the second blood collection pump.

[0012] The first blood collection pump consists of a pump body, a rotor, rollers, and a blood collection motor. The pump body has a pipe assembly groove and a central assembly hole inside. The pipe assembly groove is used to fix and assemble the blood collection tubing. The pump body has an inlet end and an outlet end on the outside according to the direction of the blood collection tubing. The inlet end is connected to the blood collection device through the blood collection tubing, and the outlet end is connected to the plasma mixing bag through the blood collection tubing. A support bushing is installed in the central assembly hole. The blood collection motor is assembled on one side of the pump body. The output end of the blood collection motor passes through the support bushing. The rotor is fixedly assembled to the output end of the blood collection motor and fits against the support bushing. The rollers are assembled at both ends of the rotor.

[0013] The structure and function of the second blood collection pump are the same as those of the first blood collection pump;

[0014] The plasma mixing bag is placed on the mixer. The plasma mixing bag is provided with a first inlet, a second inlet and a first outlet. The first inlet is connected to the outlet end of the first blood collection pump through a collection and delivery hose. The second inlet is connected to the anticoagulant storage device through a collection and delivery hose. The first outlet is connected to the centrifugal pump through a collection and delivery hose.

[0015] Preferably, the mixer consists of a housing, rollers, and a mixing motor;

[0016] The number of rollers is several, and they are arranged in an array inside the housing. Each roller has pulleys on both sides, and the pulleys of each roller are connected by a belt. The mixing motor is mounted on the outside of the housing, and the output end of the mixing motor is connected to the first roller. The housing is also equipped with a clamp to clamp and fix the plasma mixing bag.

[0017] Preferably, the centrifugal pump is controlled by an electronic monitoring component, and the centrifugal pump is provided with an inlet and an outlet. The inlet is connected to the plasma mixing bag through a collection and delivery hose, and the outlet is connected to the second blood collection pump through a collection and delivery hose.

[0018] Preferably, a sentinel observation chamber and an electric valve are provided between the centrifugal pump and the second blood collection pump. The plasma output by the centrifugal pump will enter the sentinel observation chamber in advance and be monitored in real time by an electronic monitoring component. If the liquid entering the sentinel observation chamber is plasma, the electric valve is in the open state, and the second blood collection pump operates normally to receive plasma. If the liquid entering the sentinel observation chamber is not plasma, the electronic monitoring component issues a warning signal, the electric valve closes, and the centrifugal pump stops operating.

[0019] Preferably, the electronic monitoring component consists of an electronic monitoring head and a PC control center. The PC control center can control the operation of each component, and the electronic monitoring head can monitor the working status of each component in real time.

[0020] Preferably, the inlet end of the second blood collection pump is connected to a centrifugal pump, and the outlet end is connected to a plasma storage bag via a blood collection and delivery hose.

[0021] Preferably, the support bushing has a ball bearing at one end that fits the rotor component, and the ball bearing is a plurality of balls arranged in a circumferential array along the central axis of the support bushing.

[0022] Preferably, the roller is covered with a soft pad.

[0023] Preferably, the cross-section of the roller has an irregular structure with three circular protrusions arranged in an array along the central axis.

[0024] Preferably, the blood collection device, plasma mixing bag, blood collection tubing, and plasma storage bag are all disposable items.

[0025] Compared with the prior art, the present invention has the following beneficial effects:

[0026] (1) The blood is mixed evenly and the damage to blood components is avoided. The plasma mixing bag is equipped with a mixer with a roller with a special cross section. The blood and anticoagulant are fully and evenly mixed by the uniform peristaltic motion. At the same time, the design of the roller wrapped with a soft pad and the mixer moving at a uniform speed can effectively avoid mechanical damage to red blood cells, platelets and other components in the blood, ensure the quality of subsequent blood transfusions, and avoid the impact of component damage on the medical use effect.

[0027] (2) The plasma collection accuracy is high. The centrifugal pump and the second blood collection pump are connected in series with the sentinel observation chamber and electric valve, and are equipped with electronic monitoring components to realize real-time monitoring and on / off control. It can accurately identify whether the liquid in the sentinel observation chamber is plasma. If it is not plasma, it will immediately issue an alarm and shut down the relevant components to prevent non-plasma liquid from entering the collection process. It ensures the purity of the collected plasma from the process and meets the clinical medical needs for the precise use of plasma.

[0028] (3) The entire collection process is automated and precisely controlled. It is equipped with an electronic monitoring component consisting of an electronic monitoring head and a PC control center. It is electrically connected to all functional components of the device. According to the clinical needs of different patients, the core indicators such as blood collection volume, pump operating parameters, and mixer peristalsis speed can be preset. At the same time, the working status of each component is monitored in real time, and the blood collection volume of the blood pump and the start and stop of each component are precisely controlled. It replaces manual control and realizes the automation of the entire plasma collection process, improving the accuracy and controllability of the collection process.

[0029] (4) Accurate blood collection measurement: The first and second blood collection pumps drive the rollers to squeeze the collection and delivery tubing to achieve one-way liquid delivery. The liquid delivery volume can be accurately calculated by the cross-sectional area and extrusion length of the collection and delivery tubing. The electronic monitoring component can control the collection volume in real time and accurately, and can flexibly adjust the blood collection volume according to the specific conditions of different patients to accurately match the personalized plasma collection needs of clinical patients. Attached Figure Description

[0030] Figure 1 This is a schematic diagram of the overall structure of a plasma collection device for clinical medicine.

[0031] Figure 2 This is a schematic diagram of the internal structure of the first blood collection pump;

[0032] Figure 3 This is a side sectional view of the first blood collection pump;

[0033] Figure 4 A schematic diagram of the structure supporting the bushing;

[0034] Figure 5 This is a schematic diagram of the structure of a plasma mixing bag;

[0035] Figure 6 This is a schematic diagram of the mixer.

[0036] Figure 7 This is a schematic diagram of the cross-section of the roller.

[0037] The reference numerals in the accompanying drawings include:

[0038] 1. Blood collection device; 101. Puncture needle; 102. Blood collection docking end; 2. First blood collection pump; 201. Pump body; 202. Rotor; 203. Roller; 204. Blood collection motor; 205. Support bushing; 206. Ball bearing; 207. Soft pad; 208. Pipe assembly groove; 209. Inlet end; 2010. Outlet end; 2011. Central assembly hole; 3. Blood collection and delivery tubing; 4. Plasma mixing bag; 401. First inlet; 402. Second inlet; 403. First outlet 5. Anticoagulant storage unit; 6. Mixer; 601. Housing; 602. Roller; 603. Mixing motor; 604. Pulley; 605. Belt; 606. Clamp; 607. Circular protrusion; 7. Centrifugal pump; 701. Centrifugal pump body; 702. Inlet; 703. Outlet; 8. Sentinel observation chamber; 9. Electric valve; 10. Second blood collection pump; 11. Plasma storage bag; 12. Electronic monitoring component; 1201. Electronic monitoring head; 1202. PC control center. Detailed Implementation

[0039] The present invention will now be described in further detail with reference to the accompanying drawings and embodiments:

[0040] like Figure 1 As shown, the present invention provides a plasma collection device for clinical medicine, which mainly consists of a blood collection device 1, a first blood collection pump 2, a plasma mixing bag 4, an anticoagulant storage device 5, a centrifugal pump 7, a second blood collection pump 10, and a plasma storage bag 11. A mixer 6 is provided at the plasma mixing bag 4. A sentinel observation chamber 8 and an electric valve 9 are provided between the centrifugal pump 7 and the second blood collection pump 10. The whole device is also equipped with an electronic monitoring component 12.

[0041] The device is formed by connecting the blood collection device 1, the first blood collection pump 2, the plasma mixing bag 4, the anticoagulant storage device 5, the centrifugal pump 7, the second blood collection pump 10, and the plasma storage bag 11 in sequence through the blood collection and transportation hose 3, thus ensuring basic functions. A mixer 6 is provided at the plasma mixing bag 4 to ensure that the collected blood and anticoagulant are mixed evenly. An electronic monitoring component 12 is provided to detect and control the operation of each component in real time. A sentinel observation chamber 8 and an electric valve 9 are provided between the centrifugal pump 7 and the second blood collection pump 10. When used in conjunction with the electronic monitoring component 12, they can accurately control the collection of plasma after separation by the centrifugal pump 7.

[0042] Specifically, the blood collection device 1 consists of a puncture needle 101 and a blood collection docking end 102. The blood collection docking end 102 of the blood collection device 1 is connected to the first blood collection pump 2 through the blood collection and delivery tubing 3. Thus, after the puncture needle 101 enters the human body, the first blood collection pump 2 can be started to perform blood collection.

[0043] like Figures 2-3As shown, the first blood collection pump 2 consists of a pump body 201, a rotor 202, a roller 203, and a blood collection motor 204. The pump body 201 has an internal pipe assembly groove 208 and a central assembly hole 2011. The pipe assembly groove 208 is used to fix the blood collection tubing 3. The pump body 201 has an inlet end 209 and an outlet end 2010 on its outer side according to the direction of the blood collection tubing 3. The inlet end 209 connects to the blood collection device 1 via the blood collection tubing 3, and the outlet end 2010 connects to the plasma mixing bag 4 via the blood collection tubing 3. A support bushing 205 is installed in the central assembly hole 2011. The blood collection motor 204 is mounted on one side of the pump body 201. The output end of the 4 passes through the support bushing 205. The rotor 202 is fixedly mounted on the output end of the blood collection motor 204 and fits against the support bushing 205. The rollers 203 are mounted at both ends of the rotor 202. Thus, by starting the blood collection motor 204, the rotor 202 is driven to rotate. At this time, the rollers 203 fit against and squeeze the blood collection tubing 3 to squeeze out the blood in one direction along the rotation direction. At the same time, the amount squeezed out at one time is the product of the cross-sectional area of ​​the blood collection tubing 3 and the extrusion length. Therefore, the specific collection volume can be set and the real-time collection volume of the first blood collection pump 2 can be precisely controlled by the electronic monitoring component 12. The structure and function of the second blood collection pump 10 are the same as those of the first blood collection pump 2.

[0044] like Figure 5 As shown, the plasma mixing bag 4 is placed on the mixer 6. The plasma mixing bag 4 is provided with a first inlet 401, a second inlet 402 and a first outlet 403. The first inlet 401 is connected to the outlet end 2010 of the first blood collection pump 2 through the collection and delivery hose 3. The second inlet 402 is connected to the anticoagulant storage device 5 through the collection and delivery hose 3. The first outlet 403 is connected to the centrifugal pump 7 through the collection and delivery hose 3. In this way, after receiving blood from the first blood collection pump 2, it also receives anticoagulant from the anticoagulant storage device 5. The mixer 6 moves the plasma mixing bag 4 at a constant speed to make the blood and anticoagulant evenly mixed. Finally, the centrifugal pump 7 is started to extract the mixed blood from the plasma mixing bag 4. During operation, the mixer 6, the centrifugal pump 7 and the anticoagulant storage device 5 are all controlled by the electronic monitoring component 12.

[0045] like Figure 6As shown, the mixer 6 consists of a housing 601, rollers 602, and a mixing motor 603. Several rollers 602 are arrayed and assembled inside the housing 601. Each roller 602 has pulleys 604 on both sides, and the pulleys 604 of each roller 602 are connected by a belt 605. The mixing motor 603 is mounted on the outside of the housing 601, and its output end is connected to the first roller 602. A clamp 606 is also provided on the housing 601 to clamp and fix the plasma mixing bag 4. By starting the mixing motor 603, the rollers 602 rotate, and the several rollers 602 achieve uniform peristalsis on the plasma mixing bag 4, ensuring uniform mixing of blood and anticoagulant. Simultaneously, the uniform peristalsis effectively avoids mechanical damage to blood components such as red blood cells and platelets, thereby preventing a reduction in the quality of subsequent blood transfusions.

[0046] Centrifugal pump 7 is controlled by electronic monitoring component 12. Centrifugal pump 7 is provided with inlet 702 and outlet 703. Inlet 702 is connected to plasma mixing bag 4 through collection and delivery hose 3. Outlet 703 is connected to second blood collection pump 10 through collection and delivery hose 3. By starting centrifugal pump 7, mixed blood in plasma mixing bag 4 is drawn, plasma is separated and pumped out through outlet 703.

[0047] A sentinel observation chamber 8 and an electric valve 9 are provided between the centrifugal pump 7 and the second blood collection pump 10. The plasma output from the centrifugal pump 7 will enter the sentinel observation chamber 8 in advance and be monitored in real time by the electronic monitoring component 12. If the liquid entering the sentinel observation chamber 8 is plasma, the electric valve 9 is in the open state, and the second blood collection pump 10 will operate normally to receive plasma. If the liquid entering the sentinel observation chamber 8 is not plasma, the electronic monitoring component 12 will issue a warning signal, the electric valve 9 will close, and the centrifugal pump 7 will stop operating. This can further accurately control the collection of plasma and effectively prevent non-plasma liquids from mixing in, ensuring the smooth progress of subsequent medical work.

[0048] The inlet end 209 of the second blood collection pump 10 is connected to the centrifugal pump 7, and the outlet end 2010 is connected to the plasma storage bag 11 through the collection and delivery hose 3. The second blood collection pump 10 outputs the final precisely separated plasma to the plasma storage bag 11 to complete the entire plasma collection work.

[0049] The electronic monitoring component 12 consists of an electronic monitoring head 1201 and a PC control center 1202. The PC control center 1202 can control the operation of each component, and the electronic monitoring head 1201 can monitor the working status of each component in real time. For example, the preset blood collection volume can be achieved by controlling the first blood collection pump 2. The precise control of plasma separation can be achieved by controlling and monitoring the centrifugal pump 7, the sentinel observation chamber 8, and the electric valve 9. In this way, the blood collection volume can be precisely controlled according to different patients to ensure the plasma needs of subsequent medical work.

[0050] Furthermore, such as Figure 4 As shown, the support bushing 205 has a ball bearing 206 at one end that fits the rotor 202. The ball bearing 206 is a number of balls arranged in a circular array along the central axis of the support bushing 205. This ensures that the rotor 202 rotates more smoothly and ensures the accuracy of the pumped blood volume.

[0051] Furthermore, the roller 203 is covered with a soft pad 207 to avoid mechanical damage to blood components such as red blood cells and platelets, thereby avoiding a reduction in the quality of subsequent blood transfusions.

[0052] Furthermore, such as Figure 7 As shown, the cross-section of roller 602 is an irregular structure with three circular protrusions 607 distributed along the central axis, which ensures that the blood and anticoagulant are mixed evenly.

[0053] Furthermore, the blood collection device 1, plasma mixing bag 4, blood collection and delivery tubing 3, and plasma storage bag 11 are all disposable items to ensure that they are not reused and to guarantee hygiene and safety in medical work.

[0054] The specific implementation process is as follows:

[0055] The main body of this device consists of a blood collection device 1, a first blood collection pump 2, a plasma mixing bag 4, an anticoagulant storage unit 5, a centrifugal pump 7, a second blood collection pump 10, and a plasma storage bag 11. To ensure the plasma mixing effect and collection accuracy, a mixer 6 is installed at the plasma mixing bag 4. A sentinel observation chamber 8 and an electric valve 9 are connected in series between the centrifugal pump 7 and the second blood collection pump 10. An electronic monitoring component 12 is also configured to achieve centralized control and real-time monitoring of all components of the device. All components are connected via a blood collection and delivery tubing 3. The main body of the device is formed by sequentially connecting the sentinel observation chamber 8, the electric valve 9, the second blood collection pump 10, and the plasma storage bag 11. The anticoagulant storage component 5 is independently connected to the plasma mixing bag 4. The electronic monitoring component 12 is electrically connected to all the above functional components, realizing automated and precise control of the entire plasma collection process. The plasma collection work of this device relies on the electronic monitoring component 12 for full control. All components are connected and cooperate in a preset order through the collection and delivery tubing 3. The overall use process is carried out in the following steps: preliminary preparation, blood collection and mixing, plasma separation, precise collection, and collection and storage. The specific operation is as follows:

[0056] (1) Preliminary preparation: Connect the blood collection device 1, the first blood collection pump 2, the plasma mixing bag 4, the anticoagulant storage device 5, the centrifugal pump 7, the sentinel observation chamber 8, the electric valve 9, the second blood collection pump 10, and the plasma storage bag 11 in sequence through the blood collection and delivery hose 3 to complete the main assembly of the device; clamp and fix the plasma mixing bag 4 to the housing 601 of the mixer 6 through the clamp 606 to ensure that all connection parts are sealed and leak-free; and preset the blood collection volume, the peristaltic speed of the mixer 6, etc. according to the actual situation of the patient through the PC control center of the electronic monitoring component 12.

[0057] (2) Blood collection and mixing: The puncture needle 101 of the blood collection device 1 is inserted into the blood collection site of the human body. The first blood collection pump 2 is started through the PC control center. The blood collection motor 204 drives the rotor 202 to rotate. The rollers 203 at both ends of the rotor 202 fit and squeeze the blood collection and delivery tube 3, squeezing the human blood in one direction and delivering it to the plasma mixing bag 4 through the blood collection and delivery tube 3. The collection volume of the first blood collection pump 2 is controlled in real time and accurately by the electronic monitoring component 12. While the first blood collection pump 2 delivers blood to the plasma mixing bag 4, the anticoagulant storage component 5 inputs anticoagulant into the plasma mixing bag 4. The electronic monitoring component 12 starts the mixer 6. The mixing motor 603 drives the first roller 602 to rotate. Each roller 602 is linked by the belt 605. The plasma mixing bag 4 is moved at a uniform speed by the roller 602 with a special cross section, so that the blood and anticoagulant are fully and evenly mixed. The uniform peristalsis can avoid damage to red blood cells, platelets and other components in the blood.

[0058] (3) Plasma separation: After the blood and anticoagulant are mixed, the electronic monitoring component 12 starts the centrifugal pump 7. The centrifugal pump 7 draws the mixed blood from the plasma mixing bag 4 through the inlet 702, centrifuges the mixed blood and separates the plasma. The separated plasma is transported to the sentinel observation chamber 8 through the outlet 703 of the centrifugal pump 7.

[0059] (4) Accurate collection: The electronic monitoring component 12 monitors the liquid in the sentinel observation chamber 8 in real time through the electronic monitoring head 1201. If the liquid is plasma, the electric valve 9 remains open and the plasma can continue to be transported. If the liquid is non-plasma, the electronic monitoring component 12 immediately issues a warning signal, and at the same time closes the electric valve 9 and stops the centrifugal pump 7 to prevent non-plasma liquid from mixing into the subsequent collection process.

[0060] (5) Collection and storage: When the sentinel observation chamber 8 is monitored as plasma and the electric valve 9 is open, the electronic monitoring component 12 starts the second blood collection pump 10. The second blood collection pump 10 draws the plasma in the sentinel observation chamber 8 and delivers it through the collection and delivery hose 3 to the plasma storage bag 11, thus completing the accurate collection and storage of plasma.

[0061] Finally, after completing the plasma collection from the patient, remove the blood collection device 1, plasma mixing bag 4, collection and delivery tubing 3, plasma storage bag 11 and other disposable equipment and dispose of them in accordance with medical waste regulations to complete this plasma collection work.

[0062] The above descriptions are merely embodiments of the present invention, and common knowledge such as specific technical solutions and / or characteristics are not described in detail here. It should be noted that those skilled in the art can make various modifications and improvements without departing from the technical solutions of the present invention, and these should also be considered within the scope of protection of the present invention. These modifications and improvements will not affect the effectiveness of the implementation of the present invention or the practicality of the patent. The scope of protection claimed in this application should be determined by the content of its claims, and the specific embodiments described in the specification can be used to interpret the content of the claims.

Claims

1. A plasma collection device for clinical medicine, characterized in that: The device consists of a blood collection device (1), a first blood collection pump (2), a plasma mixing bag (4), an anticoagulant storage device (5), a centrifugal pump (7), a second blood collection pump (10), and a plasma storage bag (11); A mixer (6) is provided at the plasma mixing bag (4), a sentinel observation chamber (8) and an electric valve (9) are provided between the centrifugal pump (7) and the second blood collection pump (10), and the overall device is also provided with an electronic monitoring component (12). The device is formed by connecting the blood collection device (1), the first blood collection pump (2), the plasma mixing bag (4), the anticoagulant storage device (5), the centrifugal pump (7), the second blood collection pump (10), and the plasma storage bag (11) in sequence through the blood collection tubing (3). The electronic monitoring component (12) can detect and control the operation of each component in real time. A sentinel observation chamber (8) and an electric valve (9) are provided between the centrifugal pump (7) and the second blood collection pump (10). The first blood collection pump (2) consists of a pump body (201), a rotor (202), a roller (203), and a blood collection motor (204). The pump body (201) has a pipe assembly groove (208) and a central assembly hole (2011) inside. The pipe assembly groove (208) is used to fix the blood collection tubing (3). The pump body (201) has an inlet end (209) and an outlet end (2010) on the outside according to the direction of the blood collection tubing (3). The inlet end (209) is connected to the blood collection tubing (3) for blood collection. The device (1) has an outlet end (2010) that is connected to a plasma mixing bag (4) via a collection and delivery hose (3). A support bushing (205) is installed in the middle assembly hole (2011). The blood collection motor (204) is mounted on one side of the pump body (201). The output end of the blood collection motor (204) passes through the support bushing (205). The rotor (202) is fixedly mounted on the output end of the blood collection motor (204) and fits against the support bushing (205). The roller (203) is mounted at both ends of the rotor (202). The structure and function of the second blood collection pump (10) are the same as those of the first blood collection pump (2); The plasma mixing bag (4) is placed on the mixer (6). The plasma mixing bag (4) is provided with a first inlet (401), a second inlet (402) and a first outlet (403). The first inlet (401) is connected to the outlet end (2010) of the first blood collection pump (2) through the collection and delivery hose (3). The second inlet (402) is connected to the anticoagulant storage device (5) through the collection and delivery hose (3). The first outlet (403) is connected to the centrifuge pump (7) through the collection and delivery hose (3).

2. The plasma collection device for clinical medicine according to claim 1, characterized in that: The mixer (6) consists of a housing (601), rollers (602) and a mixing motor (603); The number of rollers (602) is several, and they are arranged in an array inside the housing (601). Each roller (602) has a pulley (604) on both sides. The pulleys (604) of each roller (602) are connected to each other by a belt (605). The mixing motor (603) is assembled on the outside of the housing (601), and the output end of the mixing motor (603) is connected to the first roller (602). The housing (601) is also provided with a clamp (606) to clamp and fix the plasma mixing bag (4).

3. The plasma collection device for clinical medicine according to claim 1, characterized in that: The centrifugal pump (7) is controlled by an electronic monitoring component (12). The centrifugal pump (7) is provided with an inlet (702) and an outlet (703). The inlet (702) is connected to the plasma mixing bag (4) through a collection and delivery hose (3). The outlet (703) is connected to the second blood collection pump (10) through the collection and delivery hose (3).

4. A clinical medical plasma collection device according to claim 3, characterized in that: A sentinel observation chamber (8) and an electric valve (9) are provided between the centrifugal pump (7) and the second blood collection pump (10). The plasma output by the centrifugal pump (7) will enter the sentinel observation chamber (8) in advance and be monitored in real time by the electronic monitoring component (12). If the liquid entering the sentinel observation chamber (8) is plasma, the electric valve (9) is in the open state, and the second blood collection pump (10) will run normally to receive plasma. If the liquid entering the sentinel observation chamber (8) is not plasma, the electronic monitoring component (12) will issue a warning signal, the electric valve (9) will close, and the centrifugal pump (7) will stop running.

5. A clinical medical plasma collection device according to claim 1, characterized in that: The electronic monitoring component (12) consists of an electronic monitoring head (1201) and a PC control center (1202). The operation of each component can be controlled through the PC control center (1202), and the working status of each component can be monitored in real time through the electronic monitoring head (1201).

6. A plasma collection device for clinical medicine according to claim 1, characterized in that: The inlet end (209) of the second blood collection pump (10) is connected to the centrifugal pump (7), and the outlet end (2010) is connected to the plasma storage bag (11) through the blood collection tubing (3).

7. A clinical medical plasma collection device according to claim 1, characterized in that: The support bushing (205) has a ball bearing (206) at one end that fits the rotor (202). The ball bearing (206) is a plurality of balls arranged in a circular array along the central axis of the support bushing (205).

8. A plasma collection device for clinical medicine according to claim 1, characterized in that: The roller (203) is covered with a soft pad (207).

9. A plasma collection device for clinical medicine according to claim 1, characterized in that: The roller (602) has an irregular cross-section with three circular protrusions (607) arranged in an array along the central axis.

10. A clinical medical plasma collection device according to claim 1, characterized in that: The blood collection device (1), plasma mixing bag (4), blood collection tubing (3) and plasma storage bag (11) are all disposable items.