Herbal tooth powder containing bio-enzyme multi-effect factor and preparation method thereof

Abstract

The present application provides a kind of containing herbal dentifrice of bio-enzyme multiple effect factor, including by weight percentage: water-soluble emulsified base material 32-48%;Friction agent 22-32%;Bio-enzyme multiple effect factor 2-5%;Bacteriostatic component 3-6%;Inhibit the component of dyeing 3-6%;Fresh component 6-11%;Mucous membrane repair component 1-4%;Cleaning agent 1-3%;The rest is carrier and cosolvent.The present application also proposes the preparation method of the above-mentioned containing bio-enzyme multiple effect factor of herbal dentifrice.The present application realizes the quick microemulsion of amino acid emulsified powder, so as to be able to quickly wrap, emulsify, peel off tooth stain.The best cleaning effect is achieved.The carrier is the protective component of bio-enzyme multiple effect factor, so that bio-enzyme can maintain activity in dentifrice for a long time, maintain effective cleaning function.Bacteriostatic component and inhibit the component of dyeing can form synergistic effect with bio-enzyme multiple effect factor, with longer teeth protection function.

Description

Technical Field

[0001] This invention relates to the field of oral hygiene technology, and in particular to a herbal tooth-cleaning powder containing multiple bio-enzyme factors and its preparation method. Background Technology

[0002] Teeth cleaning powder is a type of dental cleaning product that is mainly in powder form. It is primarily used to clean extrinsic stains such as tobacco stains, tea stains, and coffee stains on the surface of teeth. It also helps to remove plaque and freshen breath. Its cleaning method is different from that of regular toothpaste, and it is more inclined to physical cleaning and stain removal by adsorption. The overall texture is dry and has a noticeable granular feel. When used, it usually produces much less foam than toothpaste.

[0003] The core working principle of teeth whitening powder is to gently abrade the tooth surface with fine abrasive particles during brushing, removing pigments and plaque attached to the teeth. Some formulas also add absorbent or chelating ingredients to further absorb pigments and prevent stains from re-adhering to the teeth. Compared to regular toothpaste, teeth whitening powder is not diluted with a large amount of water, resulting in a higher concentration of effective cleaning ingredients. Therefore, its stain removal effect is more noticeable, and it is particularly effective in improving yellowing and blackening of teeth caused by long-term tea drinking and smoking. However, it cannot dissolve tartar, nor can it improve intrinsic discoloration problems such as tetracycline staining or fluorosis.

[0004] In terms of composition, most dental cleaning powders are primarily composed of mild abrasives, such as hydrated silica, calcium carbonate, and nano-hydroxyapatite, which ensure cleaning power while minimizing wear on tooth enamel. The stain-removing portion often uses mild amino acid surfactants like sodium lauroyl sarcosinate, combined with small amounts of solubilizers and flavoring agents. This enhances the cleaning and emulsification effect, improves the taste, and reduces oral dryness and irritation. However, dental cleaning powders are relatively more abrasive and not suitable for frequent, long-term use like toothpaste. Otherwise, they may excessively wear down tooth enamel, leading to tooth sensitivity, roughened tooth surfaces, and increased susceptibility to staining.

[0005] Current teeth cleaning powders still have some problems when used. First, the powder has poor dispersibility when it comes into contact with water, making it difficult to quickly form an emulsion system. This results in a slow decomposition and removal of stains such as tooth stains, tea stains, and tobacco stains, thus limiting the cleaning effect. Second, in traditional teeth cleaning products with added biological enzymes, the enzymes are prone to deactivation under conventional processing and storage conditions, resulting in poor long-term stability and making it difficult to maintain a high cleaning effect over long-term use. Summary of the Invention

[0006] To address the shortcomings of existing technologies, this invention provides a herbal teeth cleaning powder containing multiple bio-enzyme factors and its preparation method, which solves the problems of limited cleaning effect and unsuitability for long-term use in existing technologies.

[0007] In a first aspect, the present invention provides a herbal teeth-cleaning powder containing multiple bio-enzyme factors, comprising the following components by weight percentage:

[0008] Water-soluble emulsion base material: 32-48%;

[0009] Friction agent: 22-32%;

[0010] Biological enzyme multi-effect factor: 2-5%;

[0011] Antibacterial component: 3-6%;

[0012] Stain-inhibiting and stain-dissolving components: 3-6%;

[0013] Refreshing ingredients: 6-11%;

[0014] Mucosal repair components: 1-4%;

[0015] Cleaning aid: 1-3%;

[0016] Carrier and cosolvent: balance.

[0017] Preferably, the water-soluble emulsified substrate includes one of sodium lauroyl sarcosinate, acyl glutamate, and acyl glycinate.

[0018] Preferably, the friction agent includes one of hydroxyapatite, fluorapatite, tricalcium phosphate, and dicalcium hydrogen phosphate.

[0019] Preferably, the bioenzyme multifunctional factor includes one or more of lysozyme, glucose oxidase, and amylase, or a mixture thereof.

[0020] Preferably, the antibacterial component comprises a mixture of tea polyphenols, honeysuckle extract, and clove extract.

[0021] Preferably, the stain-inhibiting and stain-dissolving component comprises a mixture of zinc citrate and papain in a mass ratio of 2 to 4:1.

[0022] Preferably, the refreshing component comprises a mixture of peppermint extract, spearmint extract and β-cyclodextrin.

[0023] Preferably, the mucosal repair component includes one or a mixture of two of dipotassium glycyrrhizate and aloe vera powder.

[0024] Preferably, the cleaning aid comprises a complex of sodium phytate and pigment ions, the carrier comprises xylitol, and the cosolvent comprises a mixture of sorbitol and glycerol in a mass ratio of 1 to 2:1.

[0025] Secondly, the present invention provides a method for preparing the above-mentioned herbal teeth-cleaning powder containing multiple bio-enzyme factors, comprising the following steps:

[0026] S1. Add the water-soluble emulsion substrate, carrier, and co-solvent into the mixer and stir at 5℃-20℃ for 10-15 minutes;

[0027] S2. Add abrasive and cleaning agent, and continue mixing for 15-20 minutes;

[0028] S3. Add antibacterial components, refreshing components, and mucosal repair components, and mix for 15-20 minutes.

[0029] S4. Control the system temperature at 25℃-35℃, add the bio-enzyme multi-effect factor and stain-inhibiting and stain-dissolving components, and mix lightly for 10-12 minutes.

[0030] S5. After mixing evenly, pass through a 100-120 mesh sieve; aseptically dispense, seal, and store in the dark to obtain the finished product.

[0031] Compared with the prior art, the present invention has the following beneficial effects:

[0032] 1. This invention utilizes amino acid emulsifying powder. Upon contact with water, its hydrophilic heads (carboxylate salts and amino acid residues) rapidly form hydrogen bonds and an ion hydration layer with water molecules. The surfactant monomers quickly dissolve and disperse in the water, rapidly exceeding the critical micelle concentration (CMC), thus preventing localized aggregation and delayed dissolution. Simultaneously, the co-solvent (polyol) contained in this invention dissolves concurrently, reducing system viscosity, accelerating surfactant diffusion, adjusting water polarity, enhancing surfactant solubility in the aqueous phase, and assisting in solubilizing the oil phase, eliminating the "dissolution bottleneck." This achieves rapid microemulsification of the amino acid emulsifying powder, enabling rapid encapsulation, emulsification, and removal of dental stains, resulting in optimal cleaning performance.

[0033] 2. The carrier in this invention serves as a protective component for the multifunctional factor of biological enzymes. It covers the surface of the enzyme protein with hydrogen bonds, replaces water molecules, and forms a "hydration protective layer" to prevent the structural collapse caused by surfactant insertion and high temperature / drying. This allows the biological enzymes to maintain their activity in the dental cleaning powder for a long time and maintain effective cleaning function.

[0034] 3. The antibacterial and stain-dissolving components of the present invention can form a synergistic effect with the multi-effect factor of biological enzymes. After the biological enzymes break down the dental plaque biofilm, the teeth are then subjected to stain-dissolving and plaque removal as well as long-lasting antibacterial effects, which has a longer-lasting tooth protection function compared with traditional teeth cleaning.

[0035] 4. The refreshing component in this invention is a combination of peppermint extract, spearmint extract and β-cyclodextrin. The loose and porous structure of β-cyclodextrin fully absorbs the peppermint extract and spearmint extract, so that the fragrance is released slowly and the refreshing fragrance lasts longer.

[0036] 5. This invention precisely controls the ratio of zinc citrate to papain in the stain-inhibiting and stain-dissolving components, so that the stain-inhibiting effect is at its best, while not reducing the stability of the powder itself, thus ensuring long-term maintenance of effective stain-inhibiting ability. Detailed Implementation

[0037] The technical solutions of the present invention will be further described below with reference to the embodiments.

[0038] Example 1:

[0039] Sodium lauroyl sarcosinate: 32%;

[0040] Basic apatite: 27%;

[0041] Lysozyme: 5%;

[0042] A mixture of equal proportions of tea polyphenols, honeysuckle extract, and clove extract: 6%;

[0043] A mixture of zinc citrate and papain in a mass ratio of 2:1: 6%;

[0044] A mixture of peppermint extract, spearmint extract and β-cyclodextrin in equal proportions: 11%;

[0045] Dipotassium glycyrrhizate: 4%;

[0046] The complex of sodium phytate with white pigment ions: 3%;

[0047] The balance is a mixture of xylitol, sorbitol and glycerol in equal proportions.

[0048] The preparation method of the above-mentioned teeth cleaning powder includes the following steps:

[0049] S1. Add the water-soluble emulsion substrate, carrier, and co-solvent into the mixer and stir at 5°C for 10 minutes.

[0050] S2. Add abrasive and cleaning agent, and continue mixing for 15 minutes;

[0051] S3. Add antibacterial components, refreshing components, and mucosal repair components, and mix for 15 minutes.

[0052] S4. Control the system temperature at 25℃, add the bio-enzyme multi-effect factor and the stain-inhibiting and stain-dissolving components, and mix lightly for 10 minutes.

[0053] S5. After mixing evenly, pass through a 100-mesh sieve; aseptically dispense, seal, and store in the dark to obtain the finished product.

[0054] Example 2:

[0055] Acylglutamate: 40%;

[0056] Fluorapatite: 32%;

[0057] A mixture of lysozyme and glucose oxidase in equal proportions: 2%;

[0058] A mixture of equal parts tea polyphenols, honeysuckle extract, and clove extract: 3%;

[0059] A mixture of zinc citrate and papain in a mass ratio of 3:1: 3%;

[0060] A mixture of peppermint extract, spearmint extract, and β-cyclodextrin in equal proportions: 6%;

[0061] Aloe vera powder: 1%;

[0062] The complex of sodium phytate and green pigment ions: 1%;

[0063] The remainder is half xylitol and half sorbitol and glycerol in a mass ratio of 1.5:1.

[0064] The preparation method of the above-mentioned teeth cleaning powder includes the following steps:

[0065] S1. Add the water-soluble emulsion substrate, carrier, and co-solvent into the mixer and stir at 10°C for 12 minutes.

[0066] S2. Add abrasive and cleaning agent, and continue mixing for 18 minutes;

[0067] S3. Add antibacterial components, refreshing components, and mucosal repair components, and mix for 18 minutes.

[0068] S4. Control the system temperature at 30℃, add the bio-enzyme multi-effect factor and the stain-inhibiting and stain-dissolving components, and mix lightly for 11 minutes.

[0069] S5. After mixing evenly, pass through a 110-mesh sieve; aseptically dispense, seal, and store in the dark to obtain the finished product.

[0070] Example 3:

[0071] Acylglycine salt: 48%;

[0072] Calcium hydrogen phosphate: 22%;

[0073] Amylase: 4%;

[0074] A mixture of equal parts tea polyphenols, honeysuckle extract, and clove extract: 5%;

[0075] A mixture of zinc citrate and papain in a mass ratio of 4:1: 5%;

[0076] A mixture of peppermint extract, spearmint extract and β-cyclodextrin in equal proportions: 8%;

[0077] A mixture of dipotassium glycyrrhizate and aloe vera powder in equal proportions: 3%;

[0078] The complex of sodium phytate and blue pigment ions: 2%;

[0079] The remainder is half xylitol and the other half a mixture of sorbitol and glycerol in a mass ratio of 2:1.

[0080] The preparation method of the above-mentioned teeth cleaning powder includes the following steps:

[0081] S1. Add the water-soluble emulsion substrate, carrier, and co-solvent into the mixer and stir at 20°C for 15 minutes.

[0082] S2. Add abrasive and cleaning agent, and continue mixing for 20 minutes.

[0083] S3. Add antibacterial components, refreshing components, and mucosal repair components, and mix for 20 minutes.

[0084] S4. Control the system temperature at 35℃, add the bio-enzyme multi-effect factor and the stain-inhibiting and stain-dissolving components, and mix lightly for 12 minutes.

[0085] S5. After mixing evenly, pass through a 120-mesh sieve; aseptically dispense, seal, and store in the dark to obtain the finished product.

[0086] Comparative Example 1:

[0087] The rest of this comparative example is the same as that of Example 1, except that it does not contain the biological enzyme multi-effect factor.

[0088] Comparative Example 2:

[0089] The rest of this comparative example is the same as that of Example 1, except that it does not contain the stain-inhibiting and stain-dissolving component formed by zinc citrate and papain in a mass ratio of 2 to 4:1.

[0090] Comparative Example 3:

[0091] The rest of this comparative example is the same as that in Example 1, except that the refreshing component does not contain β-cyclodextrin.

[0092] Comparative Example 4:

[0093] The rest of this comparative example is the same as that of Example 1, except that it does not contain mucosal repair components.

[0094] The products prepared in Examples 1-3 and Comparative Examples 1-4 were compared in a comparative experiment. Mucosal irritation was measured using the HET-CAM test, and enzyme activity retention was tested after 90 days of storage at room temperature. The results are shown in Table 1.

[0095]

[0096] Table 1

[0097] As shown in Table 1, Comparative Example 1, lacking the bio-enzyme multi-effect factor, experienced a significant decrease in antibacterial rate and a partial decrease in stain removal rate; Comparative Example 2, lacking specific stain-inhibiting and stain-dissolving components, experienced a significant decrease in stain removal rate; Comparative Example 3, lacking β-cyclodextrin, resulted in a much shorter maximum fragrance retention time compared to the examples; Comparative Example 4, lacking mucosal repair components, led to an increase in mucosal irritation to mild irritation. The above data comparisons fully demonstrate the technical efficacy of the embodiments of the present invention.

[0098] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit it. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the spirit and scope of the technical solutions of the present invention, and all such modifications or substitutions should be covered within the scope of the claims of the present invention.

Claims

1. A herbal teeth-cleaning powder containing multiple bio-enzyme factors, characterized in that, Includes the following components, calculated as a percentage by weight: Water-soluble emulsion base material: 32-48%; Friction agent: 22-32%; Biological enzyme multi-effect factor: 2-5%; Antibacterial component: 3-6%; Stain-inhibiting and stain-dissolving components: 3-6%; Refreshing ingredients: 6-11%; Mucosal repair components: 1-4%; Cleaning aid: 1-3%; Carrier and cosolvent: balance.

2. The herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in claim 1, characterized in that: The water-soluble emulsified substrate includes one of sodium lauroyl sarcosinate, acyl glutamate, and acyl glycine.

3. The herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in claim 1, characterized in that: The friction agent includes one of hydroxyapatite, fluorapatite, tricalcium phosphate, and dicalcium hydrogen phosphate.

4. The herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in claim 1, characterized in that: The bioenzyme multi-effect factor includes one or more of lysozyme, glucose oxidase, and amylase, or a mixture thereof.

5. The herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in claim 1, characterized in that: The antibacterial component includes a mixture of tea polyphenols, honeysuckle extract, and clove extract.

6. The herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in claim 1, characterized in that: The stain-inhibiting and stain-dissolving component comprises a mixture of zinc citrate and papain in a mass ratio of 2 to 4:

1.

7. The herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in claim 1, characterized in that: The refreshing components include a mixture of peppermint extract, spearmint extract, and β-cyclodextrin.

8. The herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in claim 1, characterized in that: The mucosal repair component includes one or a mixture of two of the following: dipotassium glycyrrhizate and aloe vera powder.

9. The herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in claim 1, characterized in that: The cleaning aid comprises a complex of sodium phytate and pigment ions, the carrier comprises xylitol, and the solubilizer comprises a mixture of sorbitol and glycerol in a mass ratio of 1 to 2:

1.

10. The method for preparing the herbal teeth-cleaning powder containing multiple bio-enzyme factors as described in any one of claims 1-9, characterized in that, Includes the following steps: S1. Add the water-soluble emulsion substrate, carrier, and co-solvent into the mixer and stir at 5℃-20℃ for 10-15 minutes; S2. Add abrasive and cleaning agent, and continue mixing for 15-20 minutes; S3. Add antibacterial components, refreshing components, and mucosal repair components, and mix for 15-20 minutes. S4. Control the system temperature at 25℃-35℃, add the bio-enzyme multi-effect factor and stain-inhibiting and stain-dissolving components, and mix lightly for 10-12 minutes. S5. After mixing evenly, pass through a 100-120 mesh sieve; aseptically dispense, seal, and store in the dark to obtain the finished product.

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