Methods, apparatus, and systems for making a vector that competitively inhibits a pathogen in a host

Functionalized nano or micron-sized carriers manufactured using microfluidic technology can mimic pathogen protrusions and competitively inhibit pathogens from entering host cells, solving the problem of pathogen entry into host cells and achieving effective targeted prevention and treatment.

CN122206418APending Publication Date: 2026-06-12FINCURY GMBH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
FINCURY GMBH
Filing Date
2024-09-06
Publication Date
2026-06-12

AI Technical Summary

Technical Problem

Existing technologies are insufficient to effectively inhibit pathogens such as viruses and bacteria from entering host cells, leading to the spread of infection and disease.

Method used

By using microfluidic technology to manufacture nano- or micron-sized carriers, functionalized protrusions can be used to mimic the natural protrusions of pathogens, bind to the host's target region, and competitively inhibit the binding of pathogens to host cells.

Benefits of technology

It effectively reduces the likelihood of pathogens entering host cells, reduces the risk of infection and disease, and provides targeted treatment and preventive measures.

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Abstract

According to some embodiments, a method of manufacturing nanometer and / or micrometer scale materials for use in competitive inhibition of pathogens using a microfluidic device is provided. A method of manufacturing a carrier includes forming a core using a microfluidic device; combining the core with at least one protrusion; maintaining the core and the at least one protrusion at a temperature of about 3 °C to about 5 °C; and functionalizing the core by affixing the at least one protrusion to the core. Devices and systems for manufacturing a carrier are also described.
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