Reagent bottle and sample analysis apparatus

Abstract

The application discloses a reagent bottle and a sample analysis device. The reagent bottle comprises a bottle body and a bottle cap. The bottle body is a blow-molded part, and the bottle body is provided with a bottle opening. The bottle cap is an injection-molded part, and the bottle cap comprises a cap body and a shielding piece. The cap body is detachably connected with the bottle body to cover the bottle opening. The cap body is provided with a liquid suction hole, and the liquid suction hole is in communication with the bottle opening. The shielding piece is hingedly connected with the cap body. The shielding piece can be rotated to shield the liquid suction hole, so that the bottle cap seals the bottle opening. The shielding piece can be rotated to expose the liquid suction hole, so that an external device can perform liquid suction in the bottle body through the liquid suction hole. The reagent bottle has the advantages of low manufacturing cost.

Description

Technical Field

[0001] This application belongs to the field of medical device technology, and in particular relates to a reagent bottle and a sample analysis device. Background Technology

[0002] Sample analysis equipment is used in the medical diagnostic field to perform procedures such as aspiration, sample addition, mixing, and measurement. Through such analytical devices, at least one diagnostic reagent can be added manually or automatically to human or animal bodily fluids or other fluids containing analytes, and finally, biological, chemical, or physical principles are used to detect the amount of certain substances or a specific function within the body.

[0003] In related technologies, sample analysis equipment is equipped with reagent bottles to hold the test reagents. However, reagent bottles typically consist of many parts, resulting in high manufacturing costs. Summary of the Invention

[0004] This application provides a reagent bottle and a sample analysis device, which can reduce the manufacturing cost of the reagent bottle.

[0005] In a first aspect, embodiments of this application provide a reagent bottle, comprising:

[0006] Bottle body, wherein the bottle body is a blow-molded part, and the bottle body is provided with a bottle mouth; and,

[0007] A bottle cap, which is an injection-molded part, includes a cap body and a shielding member. The cap body is detachably connected to the bottle body to cover the bottle opening. The cap body has a liquid suction hole that communicates with the bottle opening. The shielding member is hinged to the cap body. The shielding member can rotate to block the liquid suction hole so that the bottle cap seals the bottle opening. The shielding member can also rotate to expose the liquid suction hole so that an external device can draw liquid from the bottle body through the liquid suction hole.

[0008] Secondly, embodiments of this application provide a reagent bottle, comprising:

[0009] Bottle body, the bottle body having a bottle mouth; and,

[0010] A bottle cap, which is a one-piece molded plastic part, includes a cap body, a blocking member, and a first elastic member. The cap body is detachably connected to the bottle body to cover the bottle opening. The cap body has a liquid suction hole that communicates with the bottle opening. The blocking member is movably connected to the cap body. The blocking member can move to block the liquid suction hole so that the bottle cap seals the bottle opening, and the blocking member can also move to expose the liquid suction hole so that an external device can draw liquid from the bottle body through the liquid suction hole. When the opening angle of the blocking member is less than a first preset value, the first elastic member can drive the blocking member to block the liquid suction hole. The opening angle of the blocking member is the angle between the blocking member and the plane where the opening of the liquid suction hole is located.

[0011] In a first aspect, embodiments of this application provide a sample analysis device, including:

[0012] A reagent containing mechanism for containing a reagent bottle as described above; and,

[0013] A reagent dispensing mechanism is used to move the reagents contained in the reagent bottle held by the reagent holding mechanism into the reaction vessel.

[0014] Technical effects of the embodiments of this application:

[0015] After the cap is placed on the bottle, the suction hole can be covered or exposed by rotating the shielding component. Covering the suction hole protects the reagent inside the bottle, while exposing it allows external equipment to perform suction operations. Furthermore, by using blow molding to manufacture the bottle body and injection molding to manufacture the cap, the number of parts in the reagent bottle is reduced, the manufacturing process is simplified, and the manufacturing cost of the reagent bottle is lowered. Attached Figure Description

[0016] The technical solution and its beneficial effects will become apparent from the following detailed description of specific embodiments of this application, in conjunction with the accompanying drawings.

[0017] Figure 1 This is a schematic diagram of the structure of the reagent bottle provided in an embodiment of this application.

[0018] Figure 2 for Figure 1 Partial sectional view of the bottle cap and bottle body shown.

[0019] Figure 3 for Figure 1 The diagram shows the first possible structure of the bottle cap.

[0020] Figure 4 4a, 4b, and 4c are respectively Figure 1 The diagram shows the reagent bottle in a sealed state, a slightly closed state, and an open state.

[0021] Figure 5 for Figure 1 The diagram shows a structural schematic of the bottle.

[0022] Figure 6 for Figure 1 The diagram shows the second structural design of the bottle cap.

[0023] Figure 7 for Figure 6 The image shows a cross-sectional view of the bottle cap.

[0024] Figure 8 This is a schematic diagram of the structure of a sample analysis device according to an embodiment of this application.

[0025] Figure 9 for Figure 8 The schematic diagram of the first opening device shown is as follows. Figure 1 .

[0026] Figure 10 for Figure 8 The schematic diagram of the first opening device shown is as follows. Figure 2 .

[0027] Figure 11 for Figure 8 The schematic diagram of the first opening device shown is as follows. Figure 3 .

[0028] Figure 12 In the diagrams 12a, 12b, 12c, 12d, 12e, 12f, 12g, and 12h, respectively, it is a schematic diagram of the state from the first step to the eighth step in the opening process of the first opening device of this application embodiment.

[0029] Figure 13 In the middle, 13a, 13b, 13c, 13d, 13e, 13f, 13g, and 13h are respectively Figure 12 Partial schematic diagrams of the pushers corresponding to 12a, 12b, 12c, 12d, 12e, 12f, 12g and 12h.

[0030] Figure 14 Figures 14a, 14b, 14c, and 14d are schematic diagrams of the first to fourth steps in the process of sealing the bottle opening with the driving shield of the first cap opening device according to an embodiment of this application.

[0031] Figure 15 for Figure 8 The schematic diagram of the second cover opening device shown is as follows. Figure 1 .

[0032] Figure 16 for Figure 8 The schematic diagram of the second cover opening device shown is as follows. Figure 2 .

[0033] Figure 17 Figures 17a, 17b, 17c, and 17d are schematic diagrams of the first to fourth steps in the working process of the second lid-opening device according to an embodiment of this application.

[0034] The labels in the diagram are as follows:

[0035] 100. Bottle body;

[0036] 11. Main body; 12. Bottle mouth; 121. Bottle mouth; 13. First limiting component;

[0037] 200. Bottle cap;

[0038] 21. Cover; 211. Liquid suction hole; 212. First side wall; 213. First top wall; 214. First sealing part; 215. Third sealing part; 216. Second connecting part; 22. Shielding member; 221. Second sealing part; 222. Second operating part; 223. First operating part; 23. First elastic member; 24. Hinge member; 241. First part; 242. Second part; 25. Second limiting member; 26. Third limiting member; 261. Abutment surface; 262. Guide slope; 263. Deformable slope;

[0039] 300. Reagent container;

[0040] 400. Reagent dispensing mechanism;

[0041] 41. First cap opening device; 411. First mounting bracket; 412. First drive unit; 413. Pushing component; 414. Buffer assembly; 4141. First rotating component; 4142. Second rotating component; 415. First mounting base; 416. Second drive unit; 417. Clamping assembly; 4171. Second mounting bracket; 4172. Clamping component; 4172a. Mounting part; 4172b. Clamping part; 4173. Second elastic component; 4174. Third elastic component; 4175. First reset component; 4176. Fourth elastic component; 42. Second cap opening device; 421. Third mounting bracket; 422. Third drive unit; 423. Pressing assembly; 4231. Pressing component; 424. Second mounting base; 425. Fourth drive unit; 43. Pipette;

[0042] 500, rack;

[0043] 51. Pre-opening cover position;

[0044] 600. Dispatch agency. Detailed Implementation

[0045] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0046] Please refer to Figure 1 and Figure 2 This application provides a reagent bottle, which includes a bottle body 100 and a bottle cap 200. The bottle body 100 has a bottle opening 121. The bottle cap 200 is installed on the bottle body 100 to seal the bottle opening 121.

[0047] In some embodiments, the bottle body 100 is a one-piece molded plastic part. For example, the bottle body 100 is a blow-molded part, which gives the bottle body 100 the advantages of being easy to mold and having low manufacturing costs.

[0048] In some embodiments, the bottle body 100 is made of polyethylene, which makes the bottle body 100 suitable for blow molding process and avoids the bottle body 100 reacting with the reagent, resulting in reagent denaturation or corrosion of the bottle body 100.

[0049] Of course, in some other embodiments, the bottle body 100 may also be made of glass, metal, or alloy, and this application embodiment does not limit this.

[0050] The bottle cap 200 includes a cap body 21 and a blocking member 22. The cap body 21 is connected to the bottle body 100 to cover the bottle opening 121. The cap body 21 has a suction hole 211, which communicates with the bottle opening 121. The blocking member 22 is hinged to the cap body 21. The blocking member 22 can rotate to block the suction hole 211, so that the bottle cap 200 seals the bottle opening 121, and the blocking member 22 can also rotate to expose the suction hole 211, so that external equipment (such as a suction needle) can draw the reagent carried in the reagent bottle through the suction hole 211. Thus, the bottle opening 121 can be opened and closed simply by rotating the blocking member 22 to block or expose the suction hole 211, making the reagent bottle easy to use.

[0051] In some embodiments, the bottle cap 200 may be a one-piece molded plastic part, so that the bottle cap 200 has the advantages of being easy to mold and low cost.

[0052] For example, the bottle cap 200 can be an injection molded part, thereby integrally injection molding the cap body 21 and the shielding part 22 that are hinged to each other, so that the bottle cap 200 has the advantages of being easy to mold and having low manufacturing cost.

[0053] In some embodiments, the cap 200 is made of polypropylene, which makes the cap 200 suitable for injection molding process and avoids the cap 200 reacting with the reagent, which would cause the reagent to denature or the bottle body 100 to be corroded by the reagent.

[0054] Of course, in some other embodiments, the bottle cap 200 may also be made of glass, metal, or alloy, and this application embodiment does not limit this.

[0055] It is also understandable that when the bottle body 100 is a blow-molded part and the bottle cap 200 is an injection-molded part, the overall manufacturing cost of the reagent bottle may be lower.

[0056] In some embodiments, the bottle body 100 and the cap body 21 are detachably connected to facilitate the assembly and disassembly of the cap 200.

[0057] For example, the bottle body 100 and the cap 21 can be threaded together. Furthermore, the threads can be manufactured on the bottle body 100 by blow molding and on the cap 21 by injection molding, so as to achieve a detachable connection between the bottle body 100 and the cap 21 at low cost.

[0058] Please continue to refer to this. Figure 3 In some embodiments, the bottle cap 200 further includes a hinge 24 connected to both the cap body 21 and the shield 22, such that the cap body 21 and the shield 22 are hinged. For example, the hinge 24 may be connected to a first side of the cap body 21 in the circumferential direction.

[0059] For example, the hinge 24 may include a first part 241 and a second part 242. The first part 241 is connected to the shield 22, and the second part 242 is connected to the cover 21. The first part 241 and the second part 242 are connected, and the first part 241 can rotate about the connection between the first part 241 and the second part 242, thereby causing the shield 22 to rotate about the cover 21.

[0060] Therefore, when the bottle cap 200 is an integrally molded injection part, compared to the hinge 24, the cap body 21 and the shield 22, which are all independently assembled parts, the embodiments of this application can reduce the number of parts and assembly steps of the bottle cap 200, thereby reducing the manufacturing cost and manufacturing difficulty of the bottle cap 200.

[0061] like Figure 2 As shown, in some embodiments, the shielding member 22 is provided with a second sealing part 221, which is press-fitted with the inner circumferential surface of the liquid suction hole 211 so that the bottle cap 200 seals the bottle mouth 121.

[0062] Accordingly, please continue to refer to Figure 4During the rotation of the blocking member 22, it can have at least the following states:

[0063] The shielding member 22 can be in a sealed state. In the sealed state, the second sealing part 221 is inserted into the liquid suction hole 211 to seal the liquid suction hole 211, thereby sealing the bottle mouth 121.

[0064] The shielding member 22 can be in a slightly closed state, and can rotate from a sealed state to a slightly closed state towards exposing the suction hole 211. In the slightly closed state, the second sealing part 221 shields the suction hole 211. Furthermore, the contact area between the second sealing part 221 and the inner circumferential surface of the suction hole 211 in the slightly closed state is smaller than the contact area in the sealed state. At this time, there may or may not be a venting gap between the inner circumferential surface of the suction hole 211 and the second sealing part 221 that connects to the outside of the reagent bottle. This embodiment of the application does not limit this.

[0065] The shield 22 can also be in an open state, in which the shield 22 fully exposes the suction hole 211, so that external devices (such as suction needles) can draw the reagent carried in the reagent bottle through the suction hole 211.

[0066] like Figure 3 As shown, in some embodiments, at least one of the bottle body 100 and the bottle cap 200 is provided with a first elastic member 23. When the opening angle of the blocking member 22 is less than a first preset value, the first elastic member 23 can drive the blocking member 22 to block the liquid absorption hole 211. The opening angle of the blocking member 22 is the angle between the blocking member 22 and the plane where the opening of the liquid absorption hole 211 is located.

[0067] Therefore, during the use of the reagent bottle, the blocking member 22 can be driven by an external device to rotate to an opening angle less than a first preset value, thereby unsealing the bottle opening 121 (or the suction hole 211). When the force of the external device is removed, the first elastic member 23 drives the blocking member 22 to rotate in the opposite direction to a slightly closed state. This eliminates the need for the external device to precisely rotate the blocking member 22 to the slightly closed state, reducing the difficulty of opening the bottle. Furthermore, when the external device does not need to suction liquid, the first elastic member 23 can drive the blocking member 22 to block the suction hole 211, thus protecting the reagent inside the bottle 100.

[0068] In some embodiments, when the opening angle of the shield 22 is greater than a first preset value, the first elastic member 23 can drive the shield 22 to expose the suction hole 211. Thus, when suction is required, the external device rotates the shield 22 to a position greater than the first preset value, facilitating the rotation of the shield 22 by the first elastic member 23 and maintaining it in the open state, so that the external device can draw the reagent contained in the reagent bottle through the suction hole 211.

[0069] It is also understandable that by using a first elastic element 23, the drive shield 22 can be selectively rotated to a slightly closed state or an open state, and the bottle cap 200 has the advantages of simple structure and low manufacturing cost.

[0070] In some implementations, the first preset value can be 40° to 60°.

[0071] Understandably, on the one hand, if the first preset value is too small, a precise force is needed to drive the shield 22 during the process of rotating it to unseal the suction hole 211, so as to prevent the opening angle of the shield 22 from exceeding the first preset value. Only then can the first elastic member 23 drive the shield 22 to rotate to a slightly closed state, ultimately making it more difficult to open the external device. On the other hand, if the first preset value is too large, the shield 22 needs to be rotated to a larger opening angle so that the first elastic member 23 can drive the shield 22 to rotate to expose the suction hole 211. Therefore, the force applied to the external device and the stroke required to drive the shield 22 to rotate increase, ultimately making it more difficult to open the external device. Thus, the embodiments of this application make it easier and more convenient to control the rotation state of the shield 22 in the external device.

[0072] For example, the first preset value can be 40°, 43.4°, 45°, 46.7°, 48°, 50°, 52.3°, 54°, 55°, 57.8°, 59° or 60°, and this application embodiment does not limit it.

[0073] In some embodiments, one end of the first elastic member 23 is connected to the outer periphery of the cover 21, and the other end of the first elastic member 23 is connected to the shielding member 22. For example, the first elastic member 23 may be connected to the side surface of the shielding member 22 near the liquid absorption hole 211.

[0074] Therefore, when the bottle cap 200 is a one-piece molded plastic part, the number of parts in the bottle cap 200 can be reduced, and the manufacturing cost can be lower.

[0075] In some embodiments, the first elastic member 23 may be strip-shaped. When the opening angle of the blocking member 22 is equal to a first preset value, the first elastic member 23 is in a straight state; when the blocking member 22 is less than the first preset value, one end of the first elastic member 23 connected to the blocking member 22 bends toward the direction close to the suction hole 211, so as to drive the blocking member 22 to block the suction hole 211; when the opening angle of the blocking member 22 is greater than the first preset value, one end of the first elastic member 23 connected to the blocking member 22 bends toward the direction away from the suction hole 211, so as to drive the blocking member 22 to expose the suction hole 211.

[0076] In some embodiments, a second connecting portion 216 protrudes from the outer periphery of the cap 21. Both the hinge 24 and the first elastic member 23 are connected between the second connecting portion 216 and the blocking member 22. Thus, by connecting the hinge 24 and the first elastic member 23 to the same position on the cap 21, the integral molding of the bottle cap 200 is simplified.

[0077] In some embodiments, there are two hinges 24, with the first elastic member 23 located between the two hinges 24. Therefore, when the first elastic member 23 drives the blocking member 22 to rotate, the hinges 24 located on different sides of the first elastic member 23 can be subjected to more even force, so that the blocking member 22 can rotate more accurately and stably to block or expose the suction hole 211.

[0078] like Figure 2 As shown, in some embodiments, the shield 22 further includes a second operating part 222, which protrudes from the outer periphery of the cover 21 to allow an external device to drive the shield 22 to rotate.

[0079] For example, the outer periphery of the cap 21 includes a first side and a second side facing different directions. The cap 21 is hinged to the shield 22 on the first side. The shield 22 is provided with a second sealing part 221 and a second operating part 222. The second sealing part 221 is interference-fitted with the inner peripheral surface of the liquid suction hole 211 so that the cap 200 seals the bottle mouth 121. The second operating part 222 protrudes from the second side and is used to be driven by an external force to rotate in a direction away from the cap 21, thereby driving the shield 22 to rotate in a direction that exposes the liquid suction hole 211, so as to unseal the bottle mouth 121.

[0080] Taking the first side and the second side as the right and left sides respectively, with the blocking member 22 located on the upper side of the cover 21 as an example, the second operating part 222 can be driven by an external force to rotate to the upper right, thereby driving the blocking member 22 to rotate in the direction of exposing the suction hole 211 (i.e., upper right). At this time, since the blocking member 22 is hinged to the right side of the cover 21, and the second operating part 222 is located on the left side of the cover 21, the lever arm of the external force acting on the second operating part 222 is longer, so as to drive the blocking member 22 to rotate in the direction of exposing the suction hole 211 (i.e., upper left) with less effort.

[0081] It should be noted that in actual use, the first side and the second side can be adjacent sides of the outer periphery of the cover 21, or they can be opposite sides. That is to say, the first side can be the left side of the cover 21 and the second side can be the front or rear side of the cover 21, or the first side can be the right side of the cover 21 and the second side can be the front, rear or left side of the cover 21. This application embodiment does not limit this.

[0082] It should also be noted that in this embodiment, the shielding member 22 rotates in the direction of exposing the suction hole 211 to unseal the bottle mouth 121. This can also be understood as the shielding member 22 rotating in the direction of exposing the suction hole 211 to release the seal between the second sealing part 221 and the suction hole 211, thereby unsealing the bottle mouth 121.

[0083] In some embodiments, the shielding member 22 includes a shielding part and a first operating part 223 connected together. The shielding part is used to shield the liquid suction hole 211. The first operating part 223 protrudes from the side of the circumferential hinge 24 of the cap body 21 (i.e., the first side). The first operating part 223 can receive external force and rotate in a direction closer to the bottle body 100 to drive the shielding part to rotate to expose the liquid suction hole 211.

[0084] For example, the shielding part may be the part of the shielding member 22 that has the above-mentioned second sealing part 221 protruding, and is connected between the first operating part 223 and the first operating part 223.

[0085] Continuing with the example of the shield 22 being located on the upper side of the cover 21, in the actual opening process, the shield 22 can be exposed by simply pushing the second operating part 222 upward, or by simply pressing the first operating part 223 downward, or by simultaneously pushing the second operating part 222 upward and pressing the first operating part 223 downward. Of course, pushing the second operating part 222 upward and pressing the first operating part 223 downward can also be done step by step. This application embodiment does not limit this, so that the shield 22 can meet the opening needs of more different scenarios.

[0086] Taking the upward pushing of the second operating part 222 and the downward pressing of the first operating part 223 as an example, which are performed in steps:

[0087] First, the second operating part 222 can be pushed upwards, thereby causing the blocking member 22 to rotate in the direction of exposing the suction hole 211. At this time, the blocking member 22 can directly rotate to the slightly closed state, or the blocking member 22 can be rotated in the opposite direction to the slightly closed state after rotating to unseal the bottle opening 121 (or unseal the suction hole 211), driven by the first elastic member 23. In the slightly closed state, the blocking member 22 can separate the inside and outside of the reagent bottle to prevent foreign objects from falling directly into the bottle body 100 from the suction hole 211 and contaminating the reagent, and can reduce the contact between the reagent in the reagent bottle and the outside air, thereby improving the stability and reliability of the reagent in the reagent bottle.

[0088] Then, when it is necessary to draw the reagent loaded in the reagent bottle from the suction hole 211 through an external device (such as a suction needle), the first operating part 223 can be pressed down to expose the suction hole 211, so that the shield 22 is in the open state, thereby allowing the suction needle to draw the reagent loaded in the reagent bottle.

[0089] Finally, when it is necessary to reseal the bottle opening 121, the middle part of the blocking member 22 or the second operating part 222 can be pressed to rotate the blocking member 22 to the second sealing part 221 to once again press against the inner circumferential surface of the suction hole 211 to achieve a sealed state.

[0090] Therefore, during the entire process of the shield 22 rotating from the sealed state to the open state, the shield 22 requires a large amount of kinetic energy when rotating from the sealed state to the slightly closed state, which can easily cause the reagent bottle to shake, resulting in the reagent inside the reagent bottle splashing out from the suction hole 211. In the actual operation of the reagent bottle in this embodiment, the shield 22 can be opened to the slightly closed state first by the second operating part 222. Then, whenever an external device (such as a suction needle) draws reagent from the reagent bottle through the suction hole 211, the shield 22 can be opened from the slightly closed state to the open state simply by the first operating part 223. This simplifies and saves effort during each subsequent suction operation by the external device, and also prevents the reagent bottle from shaking and splashing out during each suction operation.

[0091] In some embodiments, the first operating part 223 and the second operating part 222 are located at opposite ends of the shielding member 22.

[0092] Understandably, the shield 22 is hinged to the first side of the cap 21, so that the pivot point of the shield 22 (i.e., the hinge 24) is also located on the first side. The first operating part 223 protrudes from the first side of the cap 21, and the first operating part 223 and the second operating part 222 are located at opposite ends of the shield 22. This means that the second operating part 222 is away from the first side of the cap 21, so that the lever arm formed when the external device pushes the first operating part 223 upward is longer, so as to make it easier to unseal the bottle mouth 121 with less effort, and at the same time reduce the deformation of the first operating part 223.

[0093] Please continue to refer to this. Figure 5 and Figure 6 In some embodiments, the bottle body 100 is provided with a first limiting member 13 and the bottle cap 200 is provided with a second limiting member 25. The first limiting member 13 is used to abut against the second limiting member 25 to limit the travel of the cap body 21 in the tightening direction.

[0094] As mentioned above, the bottle body 100 and the cap 21 can be threaded together. Therefore, the cooperation of the first limiting member 13 and the second limiting member 25 can accurately control the angle of the cap 200 in the circumferential direction of the bottle opening 121 after it is screwed onto the bottle body 100, thereby positioning the first operating part 223 and the second operating part 222 at preset positions in the circumferential direction of the bottle opening 121. Thus, after the bottle body 100 is fixed to an external device, the external device can more accurately drive the first operating part 223 and the second operating part 222.

[0095] In some embodiments, the bottle cap 200 is further provided with a third limiting member 26, which abuts against the first limiting member 13 to limit the travel of the cap 21 in the unscrewing direction.

[0096] Therefore, after the cap 21 is tightened in place, the third limiting member 26 can prevent the cap 21 from loosening, thus avoiding vibration during the transport of the reagent bottle and causing the cap 21 to rotate in the loosening direction. This prevents the reagent inside the bottle 100 from leaking from the bottle opening 121, and also prevents the cap 21 from rotating and causing changes in the circumferential position of the first operating part 223 and the second operating part 222 at the bottle opening 121, ultimately preventing external equipment from accurately driving the first operating part 223 and the second operating part 222.

[0097] In some embodiments, the third limiting member 26 and the second limiting member 25 are spaced apart in the circumferential direction of the cap 21 to create space for engaging the first limiting member 13. Thus, after the cap 21 is tightened into place, the first limiting member 13 and the second limiting member 25 can provide a better positioning effect, ensuring the accuracy of the circumferential position of the first operating part 223 and the second operating part 222 at the bottle opening 121.

[0098] In some embodiments, the third limiting member 26 includes an abutment surface 261 and a guide ramp 262. The abutment surface 261 abuts against the first limiting member 13 to restrict the rotation of the cover 21 in the loosening direction. The guide ramp 262 is connected to the abutment surface 261 and is located on one side of the abutment surface 261 in the loosening direction. The guide ramp 262 guides the first limiting member 13 to the side where the abutment surface 261 of the third limiting member 26 is located during the tightening process of the cover 21. Thus, during the tightening process of the cover 21, the guide ramp 262 and the first limiting member 13 can provide a better guiding effect, making it easier for the first limiting member 13 to engage between the third limiting member 26 and the second limiting member 25.

[0099] In some embodiments, the guide ramp 262 includes a first guide ramp, the distance between the first guide ramp and the peripheral surface of the cover 21 increasing along the tightening direction. Thus, during the tightening of the cover 21, the first limiting member 13 can slide relative to the second limiting member 25 along the first guide ramp.

[0100] In some embodiments, the guide ramp 262 includes a second guide ramp, the distance between the second guide ramp and the opening of the suction hole 211 increasing along the tightening direction. Alternatively, it can be understood that the distance between the second guide ramp and the blocking member 22 increases. Thus, during the tightening of the cover 21, the first limiting member 13 can slide relative to the second limiting member 25 along the second guide ramp.

[0101] In some embodiments, the third limiting member 26 further includes a deformable inclined surface 263. When the blocking member 22 seals the bottle opening 121, the deformable inclined surface 263 is located on the side of the third limiting member 26 away from the blocking member 22. Along the tightening direction, the distance between the deformable inclined surface 263 and the opening of the suction hole 211 increases, thereby thinning the end of the third limiting member 26 near the second limiting member 25. Therefore, during the tightening of the cap 21, the end of the third limiting member 26 near the second limiting member 25 can deform more easily, allowing the first limiting member 13 to more easily engage between the third limiting member 26 and the second limiting member 25.

[0102] In some embodiments, the bottle body 100 includes a main body portion 11 and a bottle mouth portion 12. The bottle mouth portion 12 protrudes from one side of the main body portion 11, and the end of the bottle mouth portion 12 away from the main body portion 11 forms a bottle mouth 121.

[0103] Therefore, the main body 11 can be used to fix the bottle 100 for external devices. Thus, when the external device drives the shielding member 22, it can fix the bottle 100 through the main body 11 to reduce or even avoid shaking of the bottle 100, thereby preventing the reagent carried in the reagent bottle from splashing out from the suction hole 211.

[0104] In some embodiments, the bottle neck 12 and the first limiting member 13 protrude from the same side of the main body 11 so as to cooperate with the second limiting member 25 and the third limiting member 26 on the cap 21.

[0105] Correspondingly, the second limiting member 25 and the third limiting member 26 can be disposed on the outer periphery of the cover 21, and this embodiment does not limit this.

[0106] Of course, in some other embodiments, the second limiting member 25 and the third limiting member 26 may also be disposed on the inner periphery of the cover 21, and this application embodiment does not limit this.

[0107] In some embodiments, the outer periphery of the bottle mouth 12 is provided with external threads for threaded connection with the cap 21.

[0108] Please continue to refer to this. Figure 7 In some embodiments, the cover 21 includes a first top wall 213 and a first side wall 212. The first side wall 212 is connected around the outer periphery of the first top wall 213 and is threadedly connected to the bottle body 100 so that the first top wall 213 covers the bottle mouth 121.

[0109] For example, the bottle mouth 12 of the bottle body 100 may be provided with external threads, and the first side wall 212 may be provided with internal threads to be screwed onto the bottle mouth 12, thereby giving the cap 21 the advantage of being easy to disassemble and assemble.

[0110] In some embodiments, the cap 21 further includes a first sealing portion 214. The first sealing portion 214 protrudes from the side of the first top wall 213 away from the bottle mouth 121, and the inner peripheral surface of the first sealing portion 214 forms a liquid absorption hole 211. The inner peripheral surface of the first sealing portion 214 is press-fitted with the shielding member 22 to seal the liquid absorption hole 211.

[0111] It is understandable that during the threaded connection between the cap 21 and the bottle body 100 via the first side wall 212, the first side wall 212 is prone to significant deformation when the cap 21 is tightened, and this deformation is easily transmitted directly to the first top wall 213. If the first top wall 213 directly forms the suction hole 211, it can easily cause significant deformation of the inner circumferential surface of the suction hole 211, thereby affecting the sealing of the suction hole 211 by the blocking member 22. In contrast, this embodiment forms the suction hole 211 by protruding the first sealing portion 214 on the first top wall 213, making the suction hole 211 far away from the first side wall 212. Therefore, the deformation at the first side wall 212 is difficult to transmit to the first sealing portion 214, thereby reducing or even eliminating the deformation at the suction hole 211 when the cap 21 is tightened, ultimately improving the sealing effect of the bottle cap 200.

[0112] The first sealing part 214 can be an annular protrusion, so that the inner peripheral surface of the first sealing part 214 forms a liquid suction hole 211.

[0113] In some embodiments, the shielding member 22 is provided with a second sealing part 221, the outer peripheral surface of the second sealing part 221 being press-fitted with the inner peripheral surface of the liquid suction hole 211 (i.e. the inner peripheral surface of the first sealing part 214) to seal the liquid suction hole 211.

[0114] In some embodiments, the second sealing portion 221 may be an annular protrusion, or the second sealing portion 221 may be a solid structure; the embodiments of this application do not limit this.

[0115] In some embodiments, the cap 21 further includes a third sealing portion 215. The third sealing portion 215 protrudes from the side of the first top wall 213 facing the bottle opening 121, and the outer peripheral surface of the third sealing portion 215 is press-fitted with the inner peripheral surface of the bottle opening 121 to seal the bottle opening 121.

[0116] As can be understood, as mentioned above, during the threaded connection between the cap 21 and the bottle body 100 via the first side wall 212, the first side wall 212 is prone to deformation when the cap 21 is tightened, and this deformation is easily transmitted to the first top wall 213. In this case, if a seal is formed between the first side wall 212 and the outer circumferential surface of the bottle mouth 12 of the bottle body 100, or between the first top wall 213 and the opening end face of the bottle mouth 121, the seal is likely to fail due to excessive deformation of the first side wall 212 and the first top wall 213. In contrast, this embodiment uses a third sealing part 215 protruding from the first top wall 213 to press-fit the inner circumferential surface of the bottle mouth 121 to seal the bottle mouth 121. This makes it difficult for the deformation at the first side wall 212 to be transmitted to the third sealing part 215, thereby reducing or even eliminating the deformation at the third sealing part 215 when the cap 21 is tightened, thus improving the sealing effect at the bottle mouth 121.

[0117] It is also understandable that by forming a third sealing part 215 in the cap 21 to achieve a seal between the cap 21 and the bottle mouth 121, the reagent bottle does not need to be sealed with a sealing ring between the first side wall 212 and the bottle mouth 12, thus reducing the manufacturing cost of the reagent bottle.

[0118] This application embodiment also provides a reagent bottle, including a bottle body 100 and a bottle cap 200. The bottle body 100 has a bottle opening 121. The bottle cap 200 is an integrally molded plastic part, and the bottle cap 200 includes a cap body 21, a blocking member 22, and a first elastic member 23. The cap body 21 is detachably connected to the bottle body 100 to cover the bottle opening 121. The cap body 21 has a liquid suction hole 211, which communicates with the bottle opening 121. The shielding member 22 is movably connected to the cap 21. The shielding member 22 can move to shield the suction hole 211 so that the cap 200 seals the bottle mouth 121. The shielding member 22 can also move to expose the suction hole 211 so that external devices can draw the reagent carried in the bottle 100 through the suction hole 211. When the opening angle of the shielding member 22 is less than a first preset value, the first elastic member 23 can drive the shielding member 22 to shield the suction hole 211. The opening angle of the shielding member 22 is the angle between the shielding member 22 and the plane where the opening of the suction hole 211 is located.

[0119] It is understood that in this embodiment, the bottle cap 200 can easily and conveniently open and close the bottle opening 121 by rotating the blocking member 22; and when the opening angle of the blocking member 22 is less than a first preset value, the blocking member 22 can be automatically driven by the first elastic member 23 to block the liquid absorption hole 211, thereby protecting the reagent carried inside the bottle body 100. Based on this, by integrally molding the cap body 21, the blocking member 22, and the first elastic member 23 into the bottle cap 200, the bottle cap 200 has the advantage of low manufacturing cost, thus giving the reagent bottle as a whole the advantage of low manufacturing cost.

[0120] In some embodiments, the specific structures of the bottle body 100 and the bottle cap 200 can be referred to the specific structures of the bottle body 100 and the bottle cap 200 described above, and will not be repeated here in the embodiments of this application.

[0121] The above is a description of the reagent bottles in the embodiments of this application.

[0122] Please continue to refer to this. Figure 8 This application also provides a sample analysis device, which includes a reagent holding mechanism 300 and a reagent dispensing mechanism 400. The reagent holding mechanism 300 is used to hold the reagent bottle as described above. The reagent dispensing mechanism 400 is used to transfer the reagent carried by the reagent bottle held in the reagent holding mechanism 300 to the reaction vessel. Thus, the reagent dispensing function can be realized through the sample analysis device.

[0123] For example, the reagent dispensing mechanism 400 may include a cap opening / closing device and a pipetting device 43. The cap opening / closing device is used to drive the blocking member 22 to move, so as to block or expose the suction hole 211. The pipetting device 43 is used to draw the reagent carried in the bottle 100 through the suction hole 211 and transfer it to the reaction vessel.

[0124] Therefore, when it is necessary to aspirate the reagent from the reagent bottle, the reagent dispensing mechanism 400 can drive the reagent bottle to expose the suction hole 211 through the cap opening and closing device, and the pipetting device 43 can then aspirate the reagent carried in the bottle 100 through the suction hole 211 and transfer it to the reaction vessel. When the transfer of reagent into the reaction vessel is finished, the reagent dispensing mechanism 400 can drive the reagent bottle to cover the suction hole 211 through the cap opening and closing device to protect the reagent inside the reagent bottle.

[0125] The pipetting device 43 may include a suction needle, which can be inserted into the bottle 100 through the suction port 211 to aspirate the reagent carried in the reagent bottle. The pipetting device 43 may also include a robotic arm, which drives the suction needle to move between the reagent holding mechanism 300 and the corresponding reaction container, so that after the suction needle aspirates the reagent at the reagent holding mechanism 300, it can be driven to the corresponding reaction container to transfer the reagent carried in the bottle 100 to the reaction container.

[0126] In some embodiments, the cap opening and closing device includes a first cap opening device 41 and a second cap opening device 42. The first cap opening device 41 is used to drive the blocking member 22 to rotate to a first preset angle along the direction of exposing the liquid suction hole 211, and the second cap opening device 42 is used to drive the blocking member 22 to rotate to a second preset angle along the direction of exposing the liquid suction hole 211, the second preset angle being greater than the first preset angle.

[0127] Thus, the first opening device 41 and the second opening device 42 can be used to control the rotation of the blocking member 22 to different opening angles.

[0128] For example, the first cap opening device 41 is used to drive the shielding member 22 to rotate, so as to unseal the bottle opening 121; the second cap opening device 42 is used to drive the shielding member 22 to rotate, so as to selectively expose the suction hole 211 so that the pipetting device 43 can draw the reagent carried in the bottle.

[0129] Therefore, considering that the shielding element 22 can have a sealed state, a slightly closed state, and an open state, as mentioned above, the working process of the opening and closing device can be as follows:

[0130] First, the first cap opening device 41 pushes the second operating part 222 upward, thereby causing the blocking member 22 to rotate in the direction of exposing the liquid suction hole 211 until the opening angle of the blocking member 22 is less than the first preset value, so as to unseal the bottle mouth 121 (or unseal the liquid suction hole 211).

[0131] Then, the first opening device 41 leaves the reagent bottle, and the first elastic element 23 drives the blocking element 22 to reverse a certain angle to a slightly closed state. In the slightly closed state, the blocking element 22 can separate the inside and outside of the reagent bottle to prevent foreign objects from falling directly into the bottle body 100 from the liquid suction hole 211 and contaminating the reagent, and can reduce the contact between the reagent in the reagent bottle and the outside air, thereby improving the stability and reliability of the reagent in the reagent bottle.

[0132] Next, when it is necessary to draw the reagent loaded in the reagent bottle from the suction hole 211 through the pipetting device 43, the first operating part 223 can be pressed down by the second capping device 42 to expose the suction hole 211, so that the shielding member 22 is in the open state, thereby allowing the suction needle to draw the reagent loaded in the reagent bottle.

[0133] Finally, when it is necessary to reseal the bottle opening 121, the second cap opening device 42 can push the blocking member 22 to an opening angle less than the first preset value, and then the first elastic member 23 drives the blocking member 22 to rotate to a slightly closed state. The first cap opening device 41 then presses the blocking member from the slightly closed state to the sealed state, that is, the first cap opening device 41 presses the middle part of the blocking member 22 or the second operating part 222, so that the blocking member 22 rotates to the second sealing part 221 and once again presses against the inner circumferential surface of the liquid suction hole 211 to be in a sealed state.

[0134] It is understandable that during the entire process of the shield 22 rotating from the sealed state to the open state, the shield 22 requires a large amount of kinetic energy when rotating from the sealed state to the slightly closed state, which can easily cause the reagent bottle to shake, resulting in the reagent inside the reagent bottle splashing out from the suction hole 211. Therefore, in the actual operation of the reagent bottle in this embodiment, the first opening device 41 can first open the shield 22 to the slightly closed state through the second operating part 222. Then, whenever the pipetting device 43 needs to draw reagent from the reagent bottle through the suction hole 211, the second opening device 42 can simply open the shield 22 from the slightly closed state to the open state through the first operating part 223. This makes it simpler and less strenuous for the pipetting device 43 to draw liquid each time, and also avoids the reagent bottle shaking and splashing out during each subsequent drawing of liquid by the pipetting device 43.

[0135] For example, when the first capping device 41 drives the blocking member 22 to rotate to a first preset angle in the direction of exposing the suction hole 211, the opening angle of the blocking member 22 is less than the first preset value. Therefore, the first capping device 41 can drive the blocking member 22 to rotate first, and then after the first capping device 41 separates from the blocking member 22, the first elastic member 23 can drive the blocking member 22 to rotate in the direction of blocking the suction hole 211 to a slightly closed state. Then, when the pipetting device 43 needs to aspirate the reagent carried in the reagent bottle, the second capping device 42 can drive the blocking member 22 to rotate from the slightly closed state to fully expose the suction hole 211.

[0136] In some embodiments, when the second capping device 42 drives the blocking member 22 to rotate to a second preset angle along the direction exposing the suction hole 211, the opening angle of the blocking member 22 is greater than the second preset value. Therefore, after the second capping device 42 drives the blocking member 22 to rotate to the second preset angle, the second capping device 42 can be moved away from the reagent bottle to avoid interference between the second capping device 42 and the pipetting device 43.

[0137] In some embodiments, the sample analysis device further includes a rack 500 on which a reagent holding mechanism 300 is mounted. The rack 500 has a pre-opening cap position 51 located outside the reagent holding mechanism 300 and used to hold reagent bottles.

[0138] The first capping device 41 is used to drive the shielding member 22 of the reagent bottle located at the pre-opening position 51 to rotate. The second capping device 42 is used to drive the shielding member 22 of the reagent bottle located in the reagent holding mechanism 300 to rotate. The pipetting device 43 is used to transfer the reagent carried by the reagent bottle in the reagent holding mechanism 300 to the reaction vessel.

[0139] Furthermore, on the one hand, it can avoid the first opening device 41 occupying too much space in the reagent holding mechanism 300; on the other hand, it also allows the sample analyzer to first rotate the shielding member 22 to the pre-opening position 51 outside the reagent holding mechanism 300, and then the second opening device 42 can easily and smoothly drive the shielding member 22 to expose the liquid suction hole 211 for liquid suction inside the reagent holding mechanism 300, so as to avoid the large kinetic energy generated during the process of the shielding member 22 unsealing from the sealed state affecting the stability and normal operation of the reagent holding mechanism 300.

[0140] Accordingly, the sample analyzer may also include a scheduling mechanism 600 for scheduling reagent bottles. For example, the scheduling mechanism 600 may be used to schedule the movement of reagent bottles between the pre-open cap position 51 and the reagent holding mechanism 300.

[0141] Of course, in actual use, the first opening device 41 and the second opening device 42 can also be used to achieve liquid aspiration operation of the shielding member 22 at two different opening angles, namely the first preset angle and the second preset angle, so as to meet the diverse liquid aspiration needs of the sample analyzer. This application embodiment does not limit this.

[0142] The technical solution of the embodiments of this application will be described below in conjunction with the specific structure of the first opening device 41.

[0143] Please continue to refer to this. Figure 9 The first opening device 41 may include a first mounting bracket 411, a first drive unit 412, and a pusher 413. The first drive unit 412 is mounted on the first mounting bracket 411. The pusher 413 is drively connected to the first drive unit 412, and the first drive unit 412 can drive the second operating part 222 to rotate away from the cover body 21, thereby causing the blocking member 22 to rotate in the direction of exposing the suction hole 211. Therefore, the seal at the suction hole 211 can be released.

[0144] In some embodiments, the first driving unit 412 can also drive the second operating part 222 to rotate toward the cover 21 so that the second sealing part 221 of the shielding member 22 seals the liquid suction hole 211, thereby achieving a seal at the liquid suction hole 211.

[0145] For example, when the second sealing part 221 seals the suction hole 211, thus sealing the bottle opening 121, the pusher 413 can push the second operating part 222 from bottom to top to unseal the bottle opening 121 (or the suction hole 211). When the blocking part 22 is in a slightly closed state, the pusher 413 can push the second operating part 222 from top to bottom, thus sealing the second sealing part 221 and the suction hole 211, thereby sealing the bottle opening 121.

[0146] The first drive unit 412 can be an electric motor, a cylinder, etc., and this application embodiment does not limit it.

[0147] In some embodiments, the first opening device 41 further includes a buffer assembly 414. The buffer assembly 414 is mounted on the first mounting bracket 411 and is located on the path of the shield 22 as it rotates under the drive of the pusher 413, to provide cushioning as the shield 22 moves toward exposing the suction hole 211.

[0148] As mentioned above, the shielding member 22 generates significant kinetic energy during its rotation from a sealed state to the unsealed bottle opening 121. Therefore, the buffer assembly 414 buffers the unsealing of the bottle opening 121 (or the suction hole 211) by the shielding member 22, effectively absorbing the large kinetic energy generated by the shielding member 22. This makes the unsealing of the suction hole 211 smoother and prevents reagents from splashing out of the bottle body 100.

[0149] For example, the cushioning assembly 414 includes a first rotating member 4141 and a fifth elastic member (not shown). The first rotating member 4141 is rotatably mounted to a first mounting bracket 411. The fifth elastic member is mounted to the first mounting bracket 411 and is used to drive the first rotating member 4141 to rotate toward the pusher 413 to abut against the shield 22 of the reagent bottle to provide cushioning.

[0150] The fifth elastic element can be a torsion spring, compression spring, disc spring, etc., and the embodiments of this application do not limit it.

[0151] In some embodiments, the buffer assembly 414 further includes a second rotating member 4142, which is rotatably mounted on the first mounting bracket 411. The second rotating member 4142 and the pusher 413 are located on opposite sides of the first rotating member 4141. Specifically, when the first rotating member 4141 drives the blocking member 22 to move towards exposing the suction hole 211 to a first preset angle, the second rotating member 4142 contacts the first rotating member 4141 and drives the first rotating member 4141 to move away from the pusher 413.

[0152] For example, the second rotating member 4142 can be a bearing, and the first rotating member 4141 has a curved surface that mates with the second rotating member 4142. When the blocking member 22 of the pre-opened cap position 51 moves to a first preset angle in the direction of exposing the suction hole 211, the torque applied by the second rotating member 4142 to the first rotating member 4141 drives the first rotating member 4141 to rotate away from the pushing member 413. At this time, the pushing member 413 stops pushing the blocking member 22 to rotate, so that the pushing member 413 and the first rotating member 4141 can release the blocking member 22, so as to remove the reagent bottle or drive the pushing member 413 and the first rotating member 4141 away from the reagent bottle.

[0153] In some embodiments, the pusher 413 is provided with a first reset part (not shown in the figure), and the first rotating member 4141 is provided with a second reset part (not shown in the figure), the second reset part being located on the rotation path of the first reset part. When the pusher 413 moves toward the drive shield 22 in the direction of shielding the liquid suction hole 211, the first reset part can push the second reset part, so that the first rotating member 4141 rotates toward the pusher 413 to reset.

[0154] For example, the second reset part can be disposed in the reset groove of the first rotating member 4141, and the first reset part can be a push rod movably disposed in the reset groove. When the pusher 413 pushes the blocking member 22 to rotate to the first preset angle along the direction of exposing the liquid suction hole 211, the push rod moves in the reset groove; when the pusher 413 resets, the push rod first moves to abut against the groove wall of the reset groove, and then drives the second rotating member 4142 to reset by pushing the groove wall of the reset groove.

[0155] In some embodiments, the sample analysis device includes a pre-opening cap position 51 for holding reagent bottles. A first cap opening device 41 drives the shielding member 22 of the reagent bottle located at the pre-opening cap position 51 to rotate. Correspondingly, the first cap opening device 41 may also include a first mounting base 415 and a second drive unit 416. The first mounting base 415 is slidably connected to a first mounting frame 411, allowing the first mounting frame 411 to move towards or away from the pre-opening cap position 51. The second drive unit 416 is mounted on the first mounting base 415 and is drively connected to the first mounting frame 411 for driving the first mounting frame 411 to slide.

[0156] Therefore, when the bottle opening 121 of the reagent bottle in the pre-opening cap position 51 needs to be unsealed or resealed, the second drive unit 416 can drive the first mounting bracket 411 to slide, so that the pusher 413 and the buffer assembly 414 on the first mounting bracket 411 move toward the pre-opening cap position 51 to unseal or reseal the bottle opening 121; after the bottle opening 121 of the reagent bottle is unsealed or resealed, the second drive unit 416 can drive the first mounting bracket 411 to move away from the pre-opening cap position 51 to achieve avoidance.

[0157] In some implementations, the corresponding support seat of the frame 500 may have a pre-opening cover position 51.

[0158] In some implementations, the second drive unit 416 may be an electric motor, a cylinder, etc., but this application embodiment does not limit this.

[0159] In some embodiments, the first opening device 41 further includes a clamping assembly 417. The clamping assembly 417 is used to clamp or loosen the bottle body 100 of the reagent bottle. It is understood that, as mentioned above, a large amount of kinetic energy is generated during the process of the blocking member 22 moving from a sealed state to unsealing the bottle opening 121. Therefore, the clamping assembly 417 can effectively prevent the bottle body 100 from shaking, thereby preventing the reagent inside the bottle body 100 from splashing out.

[0160] Please refer to this as well. Figure 9 and Figure 10 For example, the clamping assembly 417 may include a second mounting bracket 4171 and a clamping member 4172. The second mounting bracket 4171 is mounted on a first mounting base 415. The clamping member 4172 includes a mounting portion 4172a and a clamping portion 4172b. The mounting portion 4172a is rotatably mounted on the second mounting bracket 4171, and the clamping portion 4172b is located on the side of the mounting portion 4172a near the pre-opening cap position 51. Thus, the clamping member 4172 can use the mounting portion 4172a as a pivot point to rotate to the clamping portion 4172b to clamp or loosen the bottle body 100 of the reagent bottle.

[0161] In some embodiments, the clamping part 4172b can be used to clamp or loosen the main body 11 of the bottle body 100.

[0162] In some embodiments, the clamping member 4172 abuts against the first mounting bracket 411. When the first mounting bracket 411 moves toward the pre-opening cap position 51, it allows the clamping part 4172b to rotate toward the pre-opening cap position 51, thereby clamping the bottle body 100 of the reagent bottle. When the first mounting bracket 411 moves away from the pre-opening cap position 51, it pushes the clamping part 4172b to rotate away from the pre-opening cap position 51, thereby releasing the bottle body 100 of the reagent bottle.

[0163] For example, the portion of the clamping member 4172 located between the mounting portion 4172a and the clamping portion 4172b may abut against the first mounting bracket 411.

[0164] Furthermore, the movement of the first mounting bracket 411 can be driven by the second drive unit 416 to control the clamping member 4172 to clamp or loosen the bottle body 100 of the reagent bottle, so that the overall structure of the first cap opening device 41 is simpler.

[0165] It is understood that when the first mounting bracket 411 moves toward the pre-opening position 51, allowing the clamping part 4172b to rotate toward the pre-opening position 51, the clamping part 4172b may rotate downwards under its own weight to clamp the bottle body 100 of the reagent bottle, or the clamping part 4172b may rotate to clamp the bottle body 100 of the reagent bottle driven by other forces. This application embodiment does not limit this.

[0166] For example, the clamping assembly 417 further includes a second elastic element 4173, which is mounted on the second mounting bracket 4171 or the first mounting base 415. The second elastic element 4173 is used to drive the clamping part 4172b to rotate toward the pre-opening cover position 51.

[0167] Understandably, by driving the clamping part 4172b to rotate towards the pre-opening cap position 51 via the second elastic element 4173, the clamping part 4172b can both clamp the bottle body 100 of the reagent bottle and prevent the clamping part 4172b from rotating too far towards the pre-opening cap position 51, thus avoiding damage to the bottle body 100. Of course, this also allows the clamping part 4172b to be applicable to clamping reagent bottles of different heights, thereby improving the versatility of the clamping assembly 417.

[0168] In addition, the second elastic element 4173 can reduce the number of drive units required for the first opening device 41, thereby reducing the cost of the first opening device 41 and the entire sample analyzer.

[0169] The second elastic element 4173 can be a torsion spring, compression spring, pressure spring, disc spring, etc., and the embodiments of this application do not limit it.

[0170] In some embodiments, the second mounting bracket 4171 is slidably mounted on the first mounting base 415 so that the second mounting bracket 4171 can move toward or away from the pre-opened cover position 51.

[0171] Therefore, when the bottle opening 121 of the reagent bottle in the pre-opening cap position 51 needs to be unsealed or resealed, the second mounting bracket 4171 slides to the pre-opening cap position 51 so that the clamping member 4172 on the second mounting bracket 4171 can rotate to press the bottle body 100 of the reagent bottle in the pre-opening cap position 51; after the bottle opening 121 of the reagent bottle is unsealed or resealed, the second mounting bracket 4171 slides away from the pre-opening cap position 51 to achieve avoidance.

[0172] Please continue to refer to this. Figure 11 In some embodiments, the clamping assembly 417 further includes a third elastic element 4174, which is mounted on the first mounting base 415. The third elastic element 4174 is used to drive the second mounting bracket 4171 to move toward the pre-opening position 51. Thus, the third elastic element 4174 can reduce the drive unit required for the sliding of the first opening device 41, thereby reducing the cost of the first opening device 41 and the entire sample analysis equipment.

[0173] The third elastic element 4174 can be a torsion spring, compression spring, disc spring, etc., and this application embodiment does not limit it.

[0174] In some embodiments, the clamping assembly 417 further includes a first reset member 4175. The first reset member 4175 is disposed on the second mounting bracket 4171, and the first reset member 4175 is located on a path in which the first mounting bracket 411 slides away from the pre-opening position 51, so that when the first mounting bracket 411 moves away from the pre-opening position 51, it can drive the second mounting bracket 4171 to move away from the pre-opening position 51.

[0175] For example, the first reset member 4175 may include a reset rod, which is mounted on the first mounting bracket 411 and located on the side of the first mounting bracket 411 opposite to the pre-opening cover position 51.

[0176] Therefore, on the one hand, when the first mounting bracket 411 moves away from the pre-opening cover position 51, the first mounting bracket 411 will push the first reset member 4175 and its connected second mounting bracket 4171 to move away from the pre-opening cover position 51. On the other hand, when the first mounting bracket 411 moves towards the pre-opening cover position 51, the third elastic member 4174 can drive the second mounting bracket 4171 to also move towards the pre-opening cover position 51.

[0177] In some embodiments, the clamping assembly 417 further includes a fourth elastic element 4176. The fourth elastic element 4176 is mounted on the first mounting base 415 and is used to drive the second mounting bracket 4171 to move away from the pre-opened cover position 51. The elastic coefficient of the fourth elastic element 4176 is less than that of the third elastic element 4174.

[0178] Therefore, even if the second drive unit 416 is accidentally powered off during the operation of the sample analyzer, and the third elastic element 4174 drives the second mounting bracket 4171 to slide towards the pre-opening position 51, the fourth elastic element 4176 can provide buffering to prevent the first mounting bracket 411 from moving quickly to the pre-opening position 51 and hitting the reagent bottle at the pre-opening position 51.

[0179] Please refer to this as well. Figure 12 and Figure 13 Based on the above structure, one opening process of the first opening device 41 can be as follows:

[0180] The first step is to place the reagent bottle in the pre-opened cap position 51.

[0181] In the second step, the second drive unit 416 drives the first mounting bracket 411 to move toward the pre-opening cap position 51; at the same time, the third elastic member 4174 drives the second mounting bracket 4171 to move toward the pre-opening cap position 51, and the second elastic member 4173 drives the pressing part 4172b of the pressing member 4172 to rotate toward the pre-opening cap position 51, so that the pressing part 4172b of the pressing member 4172 presses the bottle body 100 of the reagent bottle.

[0182] In the third step, the second drive unit 416 continues to drive the first mounting bracket 411 to move toward the pre-opening position 51, so that the shield 22 of the reagent bottle is located between the pusher 413 and the buffer assembly 414.

[0183] In the fourth step, the first driving unit 412 starts to drive the pusher 413 to push the shield 22 of the reagent bottle upward (such as the second operating part 222 of the shield 22) to unseal the bottle opening 121 (or the suction hole 211) of the reagent bottle. At this time, the buffer assembly 414 provides buffer for the shield 22 to avoid the reagent bottle shaking and causing the reagent inside the reagent bottle to splash out at the moment when the shield 22 unseals the bottle opening 121 (or the suction hole 211).

[0184] In the fifth step, the first driving unit 412 continues to drive the pusher 413 to push the blocking member 22 of the reagent bottle upward, so that the first rotating member 4141 and the second rotating member 4142 of the buffer assembly 414 come into contact.

[0185] In the sixth step, the first driving unit 412 continues to drive the pusher 413 to push the reagent bottle's blocking member 22 upward, causing the blocking member 22 to rotate to a first preset angle. At this time, the second rotating member 4142 drives the first rotating member 4141 to rotate away from the pusher 413, so that the first rotating member 4141 and the pusher 413 switch from the state of clamping the blocking member 22 to the state of releasing the blocking member 22.

[0186] In the seventh step, the second drive unit 416 drives the first mounting bracket 411 to move away from the pre-opening position 51. The first mounting bracket 411 then pushes the second mounting bracket 4171 to move away from the pre-opening position 51 through the first reset member 4175, so that the first opening device 41 can avoid the position. Then, the blocking member 22 can rotate to a slightly closed state under the drive of the first elastic member 23.

[0187] In the eighth step, the first driving unit 412 drives the pusher 413 to reset, and the pusher 413 then drives the buffer assembly 414 to reset.

[0188] Please refer to this as well. Figure 14 Based on the above structure, one possible process for the drive shield 22 of the first cap opening device 41 to seal the bottle opening 121 (or the liquid suction hole 211) can be as follows:

[0189] The first step is to place the reagent bottle in the pre-opened cap position 51, and the first drive unit 412 drives the pusher 413 to rotate in the direction of pushing the shield 22 to expose the suction hole 211.

[0190] In the second step, the second drive unit 416 drives the first mounting bracket 411 to move toward the pre-opening cap position 51; at the same time, the third elastic member 4174 drives the second mounting bracket 4171 to move toward the pre-opening cap position 51, and the second elastic member 4173 drives the pressing part 4172b of the pressing member 4172 to move toward the pre-opening cap position 51, so that the pressing part 4172b of the pressing member 4172 presses the bottle body 100 of the reagent bottle.

[0191] Third, the second drive unit 416 continues to drive the first mounting bracket 411 to move toward the pre-opening position 51, so that the shield 22 of the reagent bottle is located below the pusher 413.

[0192] In the fourth step, the first driving unit 412 drives the pusher 413 to push the blocking member 22 so that the blocking member 22 rotates until the second sealing part 221 is inserted into the liquid suction hole 211 to seal the liquid suction hole 211, thereby achieving the sealing of the bottle mouth 121.

[0193] The above is an explanation of the first opening device 41 in the embodiments of this application. The technical solution of the embodiments of this application will be further described below in conjunction with the second opening device 42.

[0194] As mentioned above, the shield 22 may also include a first operating part 223. The first operating part 223 and the second operating part 222 protrude from opposite sides of the cover 21. Then, the second opening device 42 may be used to push the first operating part 223 of the shield 22 to drive the shield 22 to rotate.

[0195] Please refer to this as well. Figure 15 and Figure 16 In some embodiments, the second opening device 42 includes a third mounting bracket 421, a third drive unit 422, and a pressing assembly 423. The third drive unit 422 is mounted on the third mounting bracket 421. The pressing assembly 423 is driveably connected to the third drive unit 422 so that the third drive unit 422 can drive the pressing assembly 423 to push the blocking member 22, for example, to push the first operating part 223 of the blocking member 22 to rotate toward the cover 21.

[0196] The third drive unit 422 can be an electric motor, a cylinder, etc., and this application embodiment does not limit it.

[0197] In some embodiments, the pressing assembly 423 includes at least two pressing members 4231, at least some of which are used to push the first operating part 223 of different reagent bottles. This allows the second capping device 42 to complete the capping operation of at least two reagent bottles at a time, thereby improving the working efficiency of the second capping device 42 and the entire sample analysis equipment.

[0198] In some embodiments, the second opening device 42 further includes a second mounting base 424 and a fourth drive unit 425. The second mounting base 424 is movably connected to the third mounting bracket 421. The fourth drive unit 425 is mounted on the second mounting base 424 or the third mounting bracket 421, and is used to drive the third mounting bracket 421 to move, so that the third mounting bracket 421 drives the pressing assembly 423 to push the blocking member 22 toward blocking the liquid suction hole 211.

[0199] In some embodiments, the third mounting bracket 421 is rotatably mounted on the second mounting base 424. The second mounting base 424 is provided with a first gear. The fourth drive unit 425 includes a motor mounted on the third mounting bracket 421, and the motor output shaft of the fourth drive unit 425 is provided with a second gear. The second gear meshes with the first gear.

[0200] Therefore, the second gear and the first gear can form a planetary gear pair. When the fourth drive unit 425 drives the second gear to rotate, the second mounting base 424 can remain fixed, while the fourth drive unit 425 and the second gear rotate around the circumference of the first gear.

[0201] In some embodiments, both the first mounting base 415 and the second mounting base 424 can be fixed to the frame 500.

[0202] Please continue to refer to this. Figure 17 Based on the above structure, one possible working process of the second opening device 42 is as follows:

[0203] In the first step, the third drive unit 422 drives the pressing component 423 to move downward, so that the pressing component 423 pushes the first operating part 223 of the blocking member 22 of the reagent bottle to rotate downward, thereby causing the blocking member 22 to rotate to expose the suction hole 211, so that the pipetting device 43 can draw the reagent carried in the reagent bottle.

[0204] In the second step, the third drive unit 422 drives the pressing component 423 to move upward, and the fourth drive unit 425 drives the third mounting bracket 421 and the pressing component 423 to rotate in the forward direction, so that the pressing component 423 rotates and rises, thereby pushing the blocking member 22 to move in the direction of blocking the liquid suction hole 211.

[0205] In the third step, the third drive unit 422 continues to drive the pressing component 423 to move upward, and the fourth drive unit 425 continues to drive the third mounting bracket 421 and the pressing component 423 to rotate in the forward direction, so that the pressing component 423 continues to rotate and rise until it pushes the blocking member 22 to rotate to an opening angle less than the first preset value, and then the first elastic member 23 also synchronously drives the blocking member 22 to rotate to a slightly closed state.

[0206] In the fourth step, the fourth drive unit 425 continues to drive the pressing component 423 to move upward to reset, and the fourth drive unit 425 drives the third mounting bracket 421 and the pressing component 423 to rotate in the opposite direction and reset.

[0207] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0208] The reagent bottles and sample analysis equipment provided in the embodiments of this application have been described in detail above. Specific examples have been used to illustrate the principles and implementation methods of this application. The description of the above embodiments is only for the purpose of helping to understand the method and core ideas of this application. At the same time, for those skilled in the art, there will be changes in the specific implementation methods and application scope based on the ideas of this application. Therefore, the content of this specification should not be construed as a limitation of this application.

Claims

1. A reagent bottle, characterized in that, include: The bottle body is a blow-molded part, and the bottle body is provided with a bottle mouth; and, A bottle cap, which is an injection-molded part, includes a cap body and a shielding member. The cap body is detachably connected to the bottle body to cover the bottle opening. The cap body has a liquid suction hole that communicates with the bottle opening. The shielding member is hinged to the cap body. The shielding member can rotate to block the liquid suction hole so that the bottle cap seals the bottle opening. The shielding member can also rotate to expose the liquid suction hole so that an external device can draw liquid from the bottle body through the liquid suction hole.

2. The reagent bottle according to claim 1, characterized in that, The bottle body and the cap body are threaded together.

3. The reagent bottle according to claim 2, characterized in that, The bottle body is provided with a first limiting member, and the bottle cap is provided with a second limiting member. The first limiting member is used to abut against the second limiting member to limit the travel of the cap body in the tightening direction.

4. The reagent bottle according to claim 3, characterized in that, The bottle cap is also provided with a third limiting member, which is used to abut against the first limiting member to limit the travel of the cap in the unscrewing direction.

5. The reagent bottle according to claim 4, characterized in that, The third limiting member includes: A contact surface, the contact surface being used to abut against the first limiting member to restrict the cover from rotating along the loosening direction; and, A guide ramp is connected to the abutment surface and is located on one side of the abutment surface along the loosening direction. The guide ramp is used to guide the first limiting member to move to the side where the abutment surface of the third limiting member is located during the tightening process of the cover.

6. The reagent bottle according to claim 4, characterized in that, The third limiting member and the second limiting member are spaced apart in the circumferential direction of the cover to create space for engaging the first limiting member; and / or, The bottle body includes a main body and a bottle mouth. The bottle mouth and the first limiting member protrude from the same side of the main body. The bottle mouth is formed at the end of the bottle mouth away from the main body. The outer periphery of the bottle mouth is provided with an external thread for threaded connection with the cap.

7. The reagent bottle according to claim 2, characterized in that, The cap includes a first top wall and a first side wall. The first side wall is connected to the outer periphery of the first top wall and is threaded to the bottle body so that the first top wall covers the bottle mouth. The cover further includes at least one of a first sealing part and a third sealing part; The first sealing part protrudes from the side of the first top wall away from the bottle opening, and the liquid absorption hole is formed on the inner peripheral surface of the first sealing part. The inner peripheral surface of the first sealing part is press-fitted with the shielding member to seal the liquid absorption hole. The third sealing part protrudes from the side of the first top wall facing the bottle opening, and the outer peripheral surface of the third sealing part is interference-fitted with the inner peripheral surface of the bottle opening to seal the bottle opening.

8. The reagent bottle according to any one of claims 1 to 7, characterized in that, The bottle cap also includes a hinge, which is connected to both the cap body and the shielding member, so that the cap body and the shielding member are hinged together.

9. The reagent bottle according to claim 8, characterized in that, The shielding member includes a shielding part and a first operating part connected together. The shielding part is used to shield the liquid absorption hole. The first operating part protrudes from the side of the hinge in the circumferential direction of the cap body. The first operating part can receive external force and rotate in the direction closer to the bottle body to drive the shielding part to rotate to expose the liquid absorption hole.

10. The reagent bottle according to claim 8, characterized in that, At least one of the bottle body and the bottle cap is provided with a first elastic element. When the opening angle of the blocking element is less than a first preset value, the first elastic element can drive the blocking element to block the liquid absorption hole. The opening angle of the blocking element is the angle between the blocking element and the plane where the opening of the liquid absorption hole is located.

11. The reagent bottle according to claim 10, characterized in that, When the opening angle of the blocking member is greater than the first preset value, the first elastic member can drive the blocking member to expose the liquid absorption hole; and / or, The first preset value is 40° to 60°.

12. The reagent bottle according to claim 11, characterized in that, One end of the first elastic element is connected to the outer periphery of the cover, and the other end of the first elastic element is connected to the shielding element.

13. The reagent bottle according to claim 12, characterized in that, The outer periphery of the cover is provided with a second connecting portion, and both the hinge and the first elastic member are connected between the second connecting portion and the blocking member; and / or The number of hinges is two, and the first elastic element is located between the two hinges.

14. The reagent bottle according to any one of claims 1 to 7, characterized in that, The bottle body is made of polyethylene, and the bottle cap is made of polypropylene.

15. A reagent bottle, characterized in that, include: Bottle body, wherein the bottle body is provided with a bottle mouth; and, A bottle cap, which is a one-piece molded plastic part, includes a cap body, a blocking member, and a first elastic member. The cap body is detachably connected to the bottle body to cover the bottle opening. The cap body has a liquid suction hole that communicates with the bottle opening. The blocking member is movably connected to the cap body. The blocking member can move to block the liquid suction hole so that the bottle cap seals the bottle opening, and the blocking member can also move to expose the liquid suction hole so that an external device can draw liquid from the bottle body through the liquid suction hole. When the opening angle of the blocking member is less than a first preset value, the first elastic member can drive the blocking member to block the liquid suction hole. The opening angle of the blocking member is the angle between the blocking member and the plane where the opening of the liquid suction hole is located.

16. The reagent bottle according to claim 15, characterized in that, When the opening angle of the blocking member is greater than the first preset value, the first elastic member can drive the blocking member to expose the liquid absorption hole; and / or, The first preset value is 40° to 60°.

17. The reagent bottle according to claim 16, characterized in that, One end of the first elastic element is connected to the outer periphery of the cover, and the other end of the first elastic element is connected to the shielding element.

18. The reagent bottle according to claim 17, characterized in that, The bottle cap also includes a hinge, which is connected to both the cap body and the shielding member, so that the cap body and the shielding member are hinged together. The cover has a second connecting portion protruding from its outer periphery, and both the hinge and the first elastic member are connected between the second connecting portion and the shielding member; and / or, there are two hinges, and the first elastic member is located between the two hinges.

19. A sample analysis device, characterized in that, include: A reagent containing mechanism for containing a reagent bottle as described in any one of claims 1 to 18; and, A reagent dispensing mechanism is used to move the reagents contained in the reagent bottle held by the reagent holding mechanism into the reaction vessel.

20. The sample analysis device according to claim 19, characterized in that, The reagent dispensing mechanism includes: An opening and closing device, wherein the opening and closing device is used to drive the blocking member to move, so as to block or expose the liquid suction hole; and, A pipetting device for drawing reagents carried in the bottle through the suction port and transferring them to the reaction vessel.

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