A phenylhydrazine compound, application and pesticide bactericide thereof
By designing and synthesizing hydrazone fragment compounds, the resistance problem of SDHI fungicide was solved, achieving efficient control of a variety of plant diseases, providing a new fungicide molecular skeleton, and showing excellent potential for commercial application.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- NANJING AGRICULTURAL UNIVERSITY
- Filing Date
- 2024-12-25
- Publication Date
- 2026-06-26
AI Technical Summary
Long-term use of a single type of SDHI fungicide has led to an increase in resistant strains, necessitating the development of new varieties of highly efficient and broad-spectrum fungicides. Furthermore, the application of existing hydrazone fragments in agrochemicals has not been fully utilized.
A class of compounds containing hydrazone fragments was designed and synthesized. Compound 1aa-1bl was prepared through a specific structural synthetic route and applied to inhibit the function of succinate dehydrogenase (SDH) in pathogens to prevent and control various plant diseases.
The compounds exhibit extremely high inhibitory activity against rice sheath blight and tomato gray mold, with some compounds showing better inhibitory effects than existing commercial agents at low concentrations, overcoming the problem of pathogen resistance. They are also simple in structure and easy to prepare.
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Figure CN122277441A_ABST