A soothing, penetration enhancing, moisturizing lip composition and method of making and using same

Abstract

This invention discloses a soothing, penetration-promoting, and moisturizing lip composition, its preparation method, and its application, belonging to the field of cosmetic technology. The composition, by weight, comprises 50.0-80.0 parts of base oil, 1.0-5.0 parts of ginger root oil, 0.2-1.0 parts of *Edelweiss* callus extract, 0.1-1.5 parts of bisabolol, 2.0-5.0 parts of polyglycerol-3 diisostearate, and 0.5-5.0 parts of hydrogenated lecithin. The components synergistically enhance each other, achieving excellent comprehensive performance in transdermal penetration promotion, moisturizing, and soothing. The composition is non-irritating to the lip mucosa, contains no traditional preservatives, and has good safety performance. The preparation process of this composition is simple, suitable for industrial production, and can be used to prepare various lip cosmetics.

Description

Technical Field

[0001] This invention relates to the field of cosmetic technology, and in particular to a soothing, moisturizing, and penetrating lip composition, its preparation method, and its application. Background Technology

[0002] Lip skin is one of the most unique skin tissues in the human body. It is only one-third the thickness of facial skin and lacks sebaceous and sweat glands, making it unable to secrete oil and sweat for self-moisturization and protection. Furthermore, the stratum corneum of lip skin is extremely thin, resulting in a weak barrier function, making it highly susceptible to external environmental factors (such as dryness, cold, ultraviolet radiation, and wind), leading to problems like dryness, peeling, cracking, redness, and stinging. In addition, frequent application of lipstick, lip gloss, and other makeup products, as well as bad habits like licking or biting the lips, further damage the lip skin barrier, causing recurring lip problems and seriously affecting consumers' quality of life.

[0003] Currently, most lip care products on the market are lip balms, whose core function is to reduce moisture loss by forming a physical protective film on the lip surface, achieving a basic moisturizing effect. However, traditional lip balms generally suffer from the following insurmountable technical defects: First, poor transdermal penetration; active ingredients struggle to penetrate the lip skin barrier and remain only on the surface, failing to provide deep repair and soothing effects. Second, high irritation; to enhance transdermal penetration, chemically synthesized penetration enhancers such as azone are often used, which are highly irritating to the delicate lip mucosa and easily cause allergic reactions. Third, poor soothing effect; most products only focus on surface moisturizing and lack effective anti-inflammatory and soothing ingredients, failing to quickly relieve discomfort such as redness, swelling, and stinging. Fourth, containing traditional preservatives; preservatives are a common cause of lip skin allergies, and long-term use can increase the burden on the skin and disrupt the lip's microecological balance.

[0004] To address the aforementioned issues, existing technologies have attempted some improvements. CN110025506A discloses a scrubbing color-changing lip balm and its preparation method, comprising the following components: thickener, binder, film-forming agent, moisturizer, emollient, emulsifier, colorant, scrub agent, preservative, and bisabolol as an antioxidant. This invention's scrubbing color-changing lip balm can repair damaged epidermis, enhance the stratum corneum barrier function, and has anti-inflammatory effects. It can also improve dry and dehydrated skin and is easy to use. However, this patent application does not solve the problem of poor transdermal penetration, making it difficult for active ingredients to penetrate deep into the lip skin to exert their effects, and the product still contains preservatives. CN105326671A discloses a natural nourishing lip balm oil. This lip balm oil uses a blend of various oils such as sunflower seed oil and jojoba seed oil to improve moisturizing effects. However, this patent application also has the problem of poor transdermal penetration and does not contain effective soothing ingredients, so it cannot relieve lip irritation symptoms. In addition, it also contains the preservative ingredient phenoxyethanol, which poses a risk of causing lip skin allergies.

[0005] Therefore, developing a soothing and moisturizing lip composition that has good transdermal penetration, excellent moisturizing and soothing effects, is safe and non-irritating, and does not contain traditional preservatives remains a technical problem that urgently needs to be solved in this field. Summary of the Invention

[0006] The technical problem this invention aims to solve is to overcome the shortcomings of existing lip care products, such as poor transdermal penetration, high irritation, and inadequate soothing effects. This invention provides a soothing, penetration-enhancing, and moisturizing lip composition, its preparation method, and its application. By scientifically compounding naturally derived soothing components, penetration-enhancing components, natural preservatives, and stabilizing components, this invention achieves a synergistic effect among the components. This significantly improves the skin penetration rate of active ingredients while effectively reducing product irritation, resulting in excellent moisturizing and soothing effects.

[0007] To solve the above-mentioned technical problems, the present invention provides the following technical solution: In a first aspect, the present invention provides a soothing, penetration-promoting, and moisturizing lip composition, comprising, by weight, the following components: Base oil 50.0-80.0 parts; 1.0-5.0 parts ginger root oil; 0.2-1.0 parts of Edelweiss callus extract; Bisabolol 0.1-1.5 parts; 2.0-5.0 parts of polyglycerol-3 diisostearate; Hydrogenated lecithin 0.5-5.0 parts.

[0008] Preferably, the base oil is selected from one or more of jojoba seed oil, olive fruit oil, or sunflower seed oil, which is highly similar to human sebum and can form a continuous, breathable protective film on the surface of the lips, effectively reducing transepidermal water loss, while providing a good carrier for dissolving and dispersing other active ingredients.

[0009] Preferably, the base oil can be in the following weight proportions: 50.0 parts, 55.0 parts, 60.0 parts, 65.0 parts, 70.0 parts, 75.0 parts, or 80.0 parts; more preferably, it is 60.0-70.0 parts.

[0010] Ginger root oil contains a variety of active ingredients such as gingerol, gingerol, and gingerone. It has a broad-spectrum and highly effective inhibitory effect on common polluting microorganisms in cosmetics, such as Escherichia coli, Staphylococcus aureus, Candida albicans, and Aspergillus niger. It can completely replace traditional preservatives and extend the shelf life of products. At the same time, it has a gentle skin conditioning effect, can improve the microcirculation of the lip skin, and has a certain moisturizing effect as an oil.

[0011] Preferably, the ginger root oil can be in the following weight parts: 1.0 part, 2.0 part, 3.0 part, 4.0 part, or 5.0 part; more preferably, it is 2.0-4.0 parts.

[0012] The callus extract of Edelweiss is rich in flavonoids and phenolic acids such as chlorogenic acid, caffeic acid, and luteolin. It can reduce the release of pro-inflammatory factors such as IL-6 and TNF-α by inhibiting the NF-κB signaling pathway, thereby reducing the inflammatory response at its source and quickly relieving discomfort symptoms such as redness, swelling, stinging, and burning of the lips. At the same time, it has a strong antioxidant effect, which can eliminate free radicals, protect the skin of the lips from oxidative damage, and delay skin aging.

[0013] Preferably, the weight parts of the Edelweiss callus extract can be 0.2 parts, 0.4 parts, 0.6 parts, 0.8 parts, or 1.0 parts; more preferably, it is 0.4-0.8 parts.

[0014] Bisabolol is a natural sesquiterpene compound extracted from chamomile. It can inhibit the release of histamine and leukotrienes, reduce allergic reactions, and work synergistically with Edelweiss callus extract from different inflammatory pathways, significantly enhancing the soothing effect. It also has certain antibacterial and skin repair effects, promoting the healing of damaged skin.

[0015] Preferably, the weight parts of bisabolol can be 0.1 parts, 0.5 parts, 0.8 parts, 1.0 parts, or 1.5 parts; more preferably, it is 0.5-1.0 parts.

[0016] Polyglycerol-3 diisostearate has excellent emulsifying, stabilizing, thickening, and moisturizing effects. It can improve the viscosity and stability of the oil phase system and prevent the product from separating, separating oil, or crystallizing during storage. At the same time, it can improve the application feel of the product, making it smoother, easier to spread, and non-greasy.

[0017] Preferably, the weight parts of polyglycerol-3 diisostearate can be 2.0 parts, 3.0 parts, 3.5 parts, 4.0 parts, or 5.0 parts; more preferably, it is 3.0-4.0 parts.

[0018] Hydrogenated lecithin has a molecular structure that is highly similar to the lipid bilayer of the skin on the lips. It can insert into the lipid bilayer, increase the fluidity of the lipid bilayer, open the skin penetration channels, and promote the deep penetration of active ingredients. At the same time, it can replenish skin lipids, repair damaged skin barriers, and reduce transepidermal water loss, thus having both penetration-promoting and moisturizing effects.

[0019] Preferably, the hydrogenated lecithin can be in the following weight proportions: 0.5 parts, 2.0 parts, 2.8 parts, 3.5 parts, or 5.0 parts; more preferably, it is 2.0-3.5 parts.

[0020] In a preferred embodiment of the present invention, firstly, hydrogenated lecithin opens penetration channels through interaction with the lipid bilayer of lip skin, and polyols further expand these channels by increasing skin hydration. The synergistic effect of these two components significantly enhances the skin penetration of Edelweiss callus extract and bisabolol, allowing the active ingredients to penetrate deep into the lip skin to exert their effects. Secondly, Edelweiss callus extract exerts anti-inflammatory effects by inhibiting the NF-κB signaling pathway, while bisabolol exerts anti-allergic effects by inhibiting histamine release. The synergistic effect of these two components through different pathways results in a significantly better soothing effect than a single ingredient. Thirdly, the natural antibacterial properties of ginger root oil combined with the auxiliary antibacterial effects of polyols form a broad-spectrum, highly effective natural preservative system. Simultaneously, the skin-conditioning properties of ginger root oil enhance the resistance of lip skin, working together with the soothing components to repair damaged skin. Finally, polyglycerol-3 diisostearate improves the stability of the oil phase system, ensuring that all active ingredients remain uniformly dispersed during product storage, preventing layering, oil separation, or other phenomena, thus guaranteeing the product's performance stability throughout its shelf life. In addition, the base oil not only provides a carrier for all active ingredients, but also forms a protective film on the surface of the lips, reducing the damage of external stimuli to the lip skin and creating a favorable environment for the active ingredients to exert their effects.

[0021] More preferably, the polyol is selected from one or more of 1,2-pentanediol, 1,3-propanediol, and glycerin, which can increase the hydration of the stratum corneum, cause the keratinocytes to swell and the intercellular spaces to increase, and assist hydrogenated lecithin in further enhancing the transdermal effect; at the same time, it has certain moisturizing and antibacterial effects, which can enhance the moisturizing performance and antiseptic ability of the product.

[0022] More preferably, the moisturizer is selected from sodium hyaluronate or trehalose, which can absorb moisture from the air, increase the moisture content of the lip skin, and form a moisturizing film on the skin surface for long-lasting moisture retention, keeping the lips moisturized.

[0023] More preferably, the thickener is selected from one or more of sunflower seed wax, beeswax, and carnauba wax, which can increase the viscosity of the composition, improve the formability and spreadability of the product, make the product less likely to fall off the lips, and prolong the action time.

[0024] More preferably, the antioxidant is selected from tocopheryl acetate or ascorbate tetraisopalmitate, which can prevent the oxidation and deterioration of oils and active ingredients, extend the shelf life of the product, and also have a certain antioxidant skin care effect.

[0025] Secondly, the present invention provides a method for preparing the above-mentioned soothing, penetration-promoting, and moisturizing lip composition, comprising the following steps: S1. Heat and stir the base oil, ginger root oil, and optional thickener until homogeneous to obtain an oil-wax matrix; S2 Hydrogenated lecithin, Edelweiss callus extract and optional polyol are premixed under heating conditions and stirred until a uniform slurry is formed to obtain hydrogenated lecithin dispersion; S3. The hydrogenated lecithin dispersion is added to the oil and wax matrix, and stirred at a constant temperature until it is completely and evenly dispersed to obtain an oil and wax system containing hydrogenated lecithin. S4. Polyglycerol-3 diisostearate, optional humectant, and optional antioxidant are added to the oil-wax system containing hydrogenated lecithin, and the mixture is kept warm and stirred until homogeneous to obtain the base lipstick matrix. S5. Add bisabolol to the base lipstick matrix and stir until homogeneous to obtain the soothing, penetrating, and moisturizing lip composition.

[0026] Preferably, in step S1, the heating temperature is 75-85℃, the stirring speed is 100-300 r / min, and the stirring time is 10-20 min; In step S2, the heating temperature is 65-75℃, the premixing stirring speed is 200-500 r / min, and the stirring time is 15-30 min; In step S3, the heat preservation temperature is 65-75℃, the stirring speed is 300-600 r / min, and the stirring time is 20-40 min; In step S4, the heat preservation temperature is 65-75℃, the stirring speed is 200-400 r / min, and the stirring time is 10-20 min; In step S5, the temperature is 55-65℃, the stirring speed is 100-300 r / min, and the stirring time is 15-30 min.

[0027] Thirdly, the present invention provides the application of the above-mentioned soothing, penetration-promoting, and moisturizing lip composition in the preparation of lip cosmetics, including but not limited to lipsticks, lip glosses, lip balms, lip stains, and lip masks.

[0028] Compared with the prior art, the beneficial effects of the present invention are as follows: This invention provides a soothing, penetration-enhancing, and moisturizing lip composition, its preparation method, and its applications. By scientifically compounding soothing, penetration-enhancing, natural preservative, and stabilizing components, this invention achieves a synergistic effect among the components. This significantly improves the skin penetration rate of the active ingredients while effectively reducing product irritation, resulting in excellent comprehensive performance of transdermal penetration enhancement, moisturizing, and soothing. Furthermore, it eliminates the need for traditional preservatives, further improving product safety. The preparation process of this composition is simple, suitable for industrial production, and can be used to prepare various lip cosmetics. Detailed Implementation

[0029] The present invention will now be described in detail with reference to specific embodiments. These embodiments will help those skilled in the art to further understand the present invention, but do not limit the invention in any way. It should be noted that those skilled in the art can make various modifications and improvements without departing from the concept of the present invention, and these modifications and improvements all fall within the scope of protection of the present invention. Unless otherwise specified, the raw materials, reagents, etc., used in the embodiments and comparative examples of the present invention are commercially available.

[0030] Examples 1-9 Examples 1-9 are soothing, penetration-promoting, and moisturizing lip compositions as shown in Table 1. All components are expressed in parts by weight.

[0031] Table 1 Components Example 1 Example 2 Example 3 Example 4 Example 5 Example 6 Example 7 Example 8 Example 9 Jojoba seed oil 76.5 - - 30 20 - - - - olive fruit oil - 53.4 - 35 20 - - - - Sunflower seed oil - - 65 - 25 68.5 68 65.5 72 Ginger root oil 1 5 3 3 3 3 3 3 3 Edelweiss callus extract 0.2 1 0.6 0.6 0.6 0.6 0.6 0.6 0.6 Bisabolol 0.1 1.5 0.8 0.8 0.8 0.8 0.8 0.8 0.8 Polyglycerol-3 diisostearate 2 5 3.5 3.5 3.5 3.5 3.5 3.5 3.5 Hydrogenated lecithin 0.5 5 2.8 2.8 2.8 2.8 2.8 2.8 2.8 1,2-Pentanediol 2 - - 1.5 1 - - - - 1,3-Propanediol - 5 - 2 1 - - - - glycerin - - 3.5 - 1.5 - 3.5 3.5 - Sodium hyaluronate 1 - 3 - 1.5 3 - 3 - Trehalose - 5 - 3 1.5 - - - - Sunflower seed wax 0.5 - - 0.5 0.4 - - - - beeswax - 2 - 0.7 0.4 - - - - Brazilian carnauba wax - - 1.2 - 0.4 1.2 1.2 1.2 1.2 Tocopheryl acetate 0.1 - 0.5 - 0.25 0.5 0.5 - - Ascorbate tetraisopalmitate - 1 - 0.5 0.25 - - - - Example 1: The preparation method of the soothing, penetration-promoting, and moisturizing lip composition includes the following steps: S1 Add jojoba seed oil, ginger root oil and sunflower seed wax to the reaction vessel, heat to 80°C, stir at 200 r / min for 15 min, stir evenly to obtain the oil and wax matrix; S2 Hydrogenated lecithin, Edelweiss callus extract and 1,2-pentanediol were added to another reaction vessel, heated to 70°C, and premixed by stirring at 350 r / min for 22 min until a uniform slurry was formed, thus obtaining hydrogenated lecithin dispersion; S3. The hydrogenated lecithin dispersion is slowly added to the oil and wax matrix, kept at 70°C, and stirred at 450 r / min for 30 min until it is completely dispersed and uniform, thus obtaining an oil and wax system containing hydrogenated lecithin. S4. Polyglycerol-3 diisostearate, sodium hyaluronate, and tocopheryl acetate were added to the oil and wax system containing hydrogenated lecithin, kept at 70°C, and stirred at 300 r / min for 15 min until homogeneous to obtain the base lipstick matrix. S5. Add bisabolol to the base lipstick matrix, cool to 60°C, and stir at 200 r / min for 22 min until homogeneous to obtain the soothing, penetrating, and moisturizing lip composition.

[0032] Example 2: The preparation method of the soothing, penetration-promoting, and moisturizing lip composition includes the following steps: S1. Olive fruit oil, ginger root oil and beeswax are added to the reaction vessel, heated to 75°C, and stirred at 300r / min for 10min until uniform, to obtain the oil and wax matrix. S2 Hydrogenated lecithin, Edelweiss callus extract and 1,3-propanediol were added to another reaction vessel, heated to 65°C, and premixed by stirring at 500 r / min for 15 min until a uniform slurry was formed, thus obtaining hydrogenated lecithin dispersion; S3. The hydrogenated lecithin dispersion is slowly added to the oil and wax matrix, kept at 65°C, and stirred at 600 r / min for 20 min until it is completely dispersed and uniform, to obtain an oil and wax system containing hydrogenated lecithin. S4. Polyglycerol-3 diisostearate, trehalose, and ascorbate tetraisopalmitate were added to the oil and wax system containing hydrogenated lecithin, kept at 65°C, and stirred at 400 r / min for 10 min until uniformly mixed to obtain the base lipstick matrix. S5. Add bisabolol to the base lipstick matrix, cool to 55°C, and stir at 300 r / min for 15 min until homogeneous to obtain the soothing, penetrating, and moisturizing lip composition.

[0033] Example 3: The preparation method of the soothing, penetration-promoting, and moisturizing lip composition includes the following steps: S1. Add sunflower seed oil, ginger root oil and carnauba wax to a reaction vessel, heat to 85°C, stir at 100 r / min for 20 min, stir evenly to obtain the oil and wax matrix; S2 Hydrogenated lecithin, Edelweiss callus extract and glycerin were added to another reaction vessel, heated to 75°C, and premixed by stirring at 200 r / min for 30 min until a uniform slurry was formed, thus obtaining hydrogenated lecithin dispersion; S3. The hydrogenated lecithin dispersion is slowly added to the oil and wax matrix, kept at 75°C, and stirred at 300 r / min for 40 min until it is completely dispersed and uniform, thus obtaining an oil and wax system containing hydrogenated lecithin. S4. Polyglycerol-3 diisostearate, sodium hyaluronate, and tocopheryl acetate were added to the oil and wax system containing hydrogenated lecithin, kept at 75°C, and stirred at 200 r / min for 20 min until uniform, to obtain the base lipstick matrix. S5. Add bisabolol to the base lipstick matrix, cool to 65°C, stir at 100 r / min for 30 min until homogeneous, and obtain the soothing, penetrating and moisturizing lip composition.

[0034] Examples 4-9: The preparation method of the soothing, penetration-promoting and moisturizing lip composition is the same as that of Example 1 above (the base oil, thickener, polyol, moisturizer and antioxidant are adapted according to Table 1).

[0035] Comparative Examples 1-7 The weight parts of the raw materials used in Comparative Examples 1-7 are shown in Table 2. The preparation method is the same as that in Example 1 above (the base oil, thickener, polyol, moisturizer, and antioxidant are adjusted according to Table 2).

[0036] Table 2 Components Comparative Example 1 Comparative Example 2 Comparative Example 3 Comparative Example 4 Comparative Example 5 Comparative Example 6 Comparative Example 7 Sunflower seed oil 68 65.6 65.8 68.5 67.8 66.4 71.3 Ginger root oil - 3 3 3 3 3 3 Edelweiss callus extract 0.6 - 0.6 0.6 0.6 - 0.6 Bisabolol 0.8 0.8 - 0.8 0.8 - 0.8 Polyglycerol-3 diisostearate 3.5 3.5 3.5 - 3.5 3.5 3.5 Hydrogenated lecithin 2.8 2.8 2.8 2.8 - 2.8 - glycerin 3.5 3.5 3.5 3.5 3.5 3.5 - Sodium hyaluronate 3 3 3 3 3 3 3 Brazilian carnauba wax 1.2 1.2 1.2 1.2 1.2 1.2 1.2 Tocopheryl acetate 0.5 0.5 0.5 0.5 0.5 0.5 0.5 Effect test 1. Skin irritation test Human patch tests were conducted in accordance with the "Cosmetic Safety Technical Specifications (2015 Edition)". The compositions prepared in Examples 1-9 were selected as experimental products. Thirty healthy subjects were selected, half male and half female. Closed patch tests were performed on the inner forearm and behind the ear of the subjects. The test patch was removed after 24 hours. The skin was observed for irritation reactions such as erythema, edema, papules, and vesicles at 30 minutes, 24 hours and 48 hours after removal.

[0037] The experimental results showed that the patch test results of all 30 subjects were negative, with no irritation reactions such as erythema, edema, papules, or vesicles. This indicates that the composition prepared in the embodiments of the present invention has no obvious irritant or sensitizing effect on the human body and has good safety performance.

[0038] 2. In vitro transdermal permeation enhancement effect test A Franz diffusion cell was used. Pig skin (simulating human skin) was fixed between the supply and receiving chambers of the diffusion cell. The compositions prepared in Examples 1-9 and Comparative Examples 1-7 (each prepared as a 20 wt% solution with deionized water) were added to the supply chamber. A pH 7.4 phosphate buffer solution was added to the receiving chamber as the receiving solution. The mixture was stirred at a constant temperature of 32°C at a speed of 300 rpm for 24 hours. The content of bisabolol in the receiving solution was determined by high-performance liquid chromatography (HPLC), and the skin permeability was calculated. Higher skin permeability indicates a better transdermal penetration enhancement effect.

[0039] 3. Moisturizing efficacy test Five healthy volunteers were selected and placed in each group. Under conditions of 25°C and 45% relative humidity, the compositions prepared in Examples 1-9 and Comparative Examples 1-7 were applied to the volunteers' lips. Transepidermal water loss (TEWL) values ​​were measured before application and 8 hours after application using a transepidermal water loss meter. The average value for each group was taken, and the TEWL reduction rate before and after application was calculated. A smaller TEWL reduction rate indicates better moisturizing efficacy.

[0040] 4. Soothing efficacy test Five healthy volunteers with no history of cosmetic allergies were selected and placed in each group. The compositions prepared in Examples 1-9 and Comparative Examples 1-7 were applied to the volunteers' lips at 25°C and 45% relative humidity. After 5 minutes, the soothing score was recorded according to the following scoring criteria, and the average score was taken. A lower score indicated a better soothing effect.

[0041] Table 3 Scoring Criteria for Soothing Efficacy Test Score Scoring Criteria 0 points No itching, stinging, burning or other discomfort. 1 point Very slight discomfort, no obvious sensation 2 points Mild discomfort, perceptible but tolerable 3 points Moderate discomfort, with noticeable itching / tingling sensation. 4 points Significant discomfort, intense itching / stirring sensation 5 points Extreme discomfort, intolerable 5. Accelerated stability test The compositions prepared in Example 3 and Comparative Example 1 were subjected to accelerated stability testing in a constant temperature and humidity chamber at 40℃±2℃ and 75%±5% relative humidity for 3 months. Samples were taken at the beginning of the test, and at the first, second, and third months after the start of the test to test the appearance, odor, pH value, and microbiological indicators (total bacterial count, total mold and yeast count). Microbiological indicator testing was conducted in accordance with the "Cosmetic Safety Technical Specifications (2015 Edition)".

[0042] Test Results The results of in vitro transdermal permeation enhancement, moisturizing efficacy, and soothing efficacy tests of the compositions prepared in Examples 1-9 and Comparative Examples 1-7 are shown in Table 4.

[0043] Table 4 Sample number Bisabolol skin penetration rate (%) TEWL reduction rate (%) Relief score (points) Example 1 44.3 27.5 0.8 Example 2 45.7 26.8 0.9 Example 3 47.2 25.3 0.7 Example 4 46.8 25.7 0.8 Example 5 46.5 26.1 0.8 Example 6 40.6 28.9 0.9 Example 7 46.1 30.2 0.7 Example 8 47.0 25.2 0.8 Example 9 39.9 31.8 0.9 Comparative Example 1 43.9 28.2 0.9 Comparative Example 2 46.6 26.2 2.8 Comparative Example 3 / 26.5 2.5 Comparative Example 4 45.8 32.9 0.9 Comparative Example 5 21.5 35.7 1.8 Comparative Example 6 / 27.8 4.0 Comparative Example 7 12.3 38.4 2.1 The accelerated stability tests of the compositions prepared in Example 3 and Comparative Example 1 are shown in Table 5.

[0044] Table 5 sample time Appearance odor pH value Total bacterial count (CFU / g) Total number of mold and yeast cells (CFU / g) Example 3 initial Pale yellow, uniform paste Natural plant fragrance 6.2 <10 <10 Example 3 1 month Pale yellow, uniform paste Natural plant fragrance 6.1 <10 <10 Example 3 2 months Pale yellow, uniform paste Natural plant fragrance 6.1 <10 <10 Example 3 3 months Pale yellow, uniform paste Natural plant fragrance 6.0 <10 <10 Comparative Example 1 initial Pale yellow, uniform paste grease smell 6.2 <10 <10 Comparative Example 1 1 month Pale yellow, uniform paste Slight rancid smell 6.0 120 <10 Comparative Example 1 2 months Pale yellow, uniform paste A distinct rancid smell 5.8 850 30 Comparative Example 1 3 months Pale yellow, uniform paste Strong rancid smell 5.5 2300 120 This invention scientifically combines soothing, penetration-enhancing, natural preservative, and stabilizing components to create a synergistic effect. This significantly improves the skin penetration rate of active ingredients while effectively reducing product irritation, achieving excellent comprehensive performance in transdermal penetration, moisturizing, and soothing. More specifically, bisabolol achieves a skin penetration rate (%) ≥39.9%, a TEWL reduction rate (%) ≤31.8%, and a soothing score ≤0.9, significantly superior to the comparative examples. After storage at 40℃ and 75% relative humidity for 3 months, the composition obtained in this invention showed no significant changes in appearance, odor, or pH value, and all microbiological indicators met the requirements of the "Cosmetic Safety Technical Specifications (2015 Edition)".

[0045] The main function of ginger root oil is antibacterial and preservative. As an oil, it also has a certain moisturizing effect. Compared with Example 3, Comparative Example 1 did not add ginger root oil, and the TEWL reduction rate decreased.

[0046] Edelweiss callus extract and bisabolol are the core soothing components. Compared with Example 3, the absence of either component in Comparative Examples 2 and 3 would lead to a significant decrease in the soothing effect, while the absence of both components in Comparative Example 6 would result in the product basically losing its soothing function, proving that the two have a significant synergistic effect.

[0047] Hydrogenated lecithin is the core penetration-enhancing component. Compared with Example 3, Comparative Example 5, without the addition of hydrogenated lecithin, will significantly reduce the penetration rate of bisabolol, and at the same time affect the moisturizing and soothing effects. Comparative Example 7, without the addition of hydrogenated lecithin and polyol, the transdermal penetration, moisturizing and soothing effects are all significantly reduced.

[0048] Polyglycerol-3 diisostearate mainly improves the stability of the system and the moisturizing effect. Compared with Example 3, Comparative Example 4 does not contain polyglycerol-3 diisostearate, and the moisturizing effect is reduced.

[0049] Accelerated stability testing results showed that the composition prepared in the embodiments of the present invention with added ginger root oil showed no significant changes in appearance, odor, or pH value after storage for 3 months at 40°C and 75% relative humidity, and all microbiological indicators met the requirements of the "Cosmetic Safety Technical Specifications (2015 Edition)". In contrast, the comparative sample (Sample 1) without added ginger root oil showed excessive microbial levels after 3 months of storage, with the number of microorganisms increasing dramatically with prolonged storage time, and exhibiting obvious rancidity. This demonstrates that ginger root oil has excellent natural preservative effects and can effectively extend the shelf life of the product.

[0050] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and are not intended to limit the scope of protection of the present invention. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can be made to the technical solutions of the present invention without departing from the essence and scope of the technical solutions of the present invention.

Claims

1. A soothing, penetration enhancing, moisturizing lip composition characterized in that, Based on parts by weight, it includes the following components: Base oil 50.0-80.0 parts; 1.0-5.0 parts ginger root oil; 0.2-1.0 parts of Edelweiss callus extract; Bisabolol 0.1-1.5 parts; 2.0-5.0 parts of polyglycerol-3 diisostearate; Hydrogenated lecithin 0.5-5.0 parts.

2. The soothing penetration enhancing moisturizing lip composition of claim 1, wherein, It may also optionally include one or more of the following components: Polyols 2.0-5.0 parts; Moisturizer 1.0-5.0 parts; Thickener 0.5-2.0 parts; Antioxidant 0.1-1.0 parts.

3. The soothing penetration enhancing moisturizing lip composition according to claim 1 or 2, characterized in that, The base oil is selected from one or more of jojoba seed oil, olive fruit oil, or sunflower seed oil.

4. The soothing penetration enhancing moisturizing lip composition of claim 2, wherein The polyol is selected from one or more of 1,2-pentanediol, 1,3-propanediol, and glycerol.

5. The soothing penetration enhancing moisturizing lip composition of claim 2, wherein The moisturizer is selected from sodium hyaluronate or trehalose.

6. The soothing penetration enhancing moisturizing lip composition of claim 2, wherein The thickener is selected from one or more of sunflower seed wax, beeswax, and carnauba wax.

7. The soothing penetration enhancing moisturizing lip composition of claim 2, wherein The antioxidant is selected from tocopheryl acetate or ascorbate tetraisopalmitate.

8. A method of preparing a soothing, penetration enhancing, moisturizing lip composition according to any one of claims 1-7, characterized in that, Includes the following steps: S1. Heat and stir the base oil, ginger root oil, and optional thickener until homogeneous to obtain an oil-wax matrix; S2 Hydrogenated lecithin, Edelweiss callus extract and optional polyol are premixed under heating conditions and stirred until a uniform slurry is formed to obtain hydrogenated lecithin dispersion; S3. The hydrogenated lecithin dispersion is added to the oil and wax matrix, and stirred at a constant temperature until it is completely and evenly dispersed to obtain an oil and wax system containing hydrogenated lecithin. S4. Polyglycerol-3 diisostearate, optional humectant, and optional antioxidant are added to the oil-wax system containing hydrogenated lecithin, and the mixture is kept warm and stirred until homogeneous to obtain the base lipstick matrix. S5. Add bisabolol to the base lipstick matrix and stir until homogeneous to obtain the soothing, penetrating, and moisturizing lip composition.

9. The preparation method according to claim 8, characterized in that, In step S1, the heating temperature is 75-85℃, the stirring speed is 100-300 r / min, and the stirring time is 10-20 min; In step S2, the heating temperature is 65-75℃, the premixing stirring speed is 200-500 r / min, and the stirring time is 15-30 min; In step S3, the heat preservation temperature is 65-75℃, the stirring speed is 300-600 r / min, and the stirring time is 20-40 min; In step S4, the heat preservation temperature is 65-75℃, the stirring speed is 200-400 r / min, and the stirring time is 10-20 min; In step S5, the temperature is 55-65℃, the stirring speed is 100-300 r / min, and the stirring time is 15-30 min.

10. The use of a soothing, penetration-enhancing, and moisturizing lip composition as described in any one of claims 1-7 in the preparation of lip cosmetics, characterized in that, The cosmetics for the lips include, but are not limited to, lipsticks, lip glosses, lip balms, lip stains, and lip masks.