Liquid storage device, method for controlling the same, and sample testing apparatus

Abstract

This application discloses a liquid storage device and its control method, as well as a sample testing device. The reagent storage mechanism of the liquid storage device stores reagents required for testing by the sample testing device; a pressure storage mechanism provides positive pressure to the reagent storage mechanism; the inlet end of the power mechanism is connected to the reagent storage mechanism via a first pipeline, and the outlet end of the power mechanism is connected to the pressure storage mechanism via a second pipeline; wherein, when the first pipeline is open, the power mechanism provides negative pressure to the reagent storage mechanism, and / or, when the second pipeline is open, the power mechanism provides positive pressure to the pressure storage mechanism. The liquid storage device of this application can establish positive pressure using one port of the power mechanism, enabling the power mechanism to provide positive pressure to the pressure storage mechanism, and / or establish negative pressure using the other port of the power mechanism, thereby reducing the use of piping components, simplifying the structure, and effectively reducing the production cost of the liquid storage device.

Description

Technical Field

[0001] This application relates to the field of sample testing technology, and in particular to liquid storage devices and their control methods, and sample testing equipment. Background Technology

[0002] Existing sample testing equipment requires reagent storage via a reservoir to provide reagent support and ensure the reliability and stability of sample testing. This existing reservoir system utilizes two power mechanisms for both reagent storage and operation: one mechanism establishes negative pressure to drive reagents into the storage chamber, and the other establishes positive pressure to allow reagents to flow from the storage chamber into other components of the sample testing equipment for use, thus meeting the system's operational requirements.

[0003] When existing liquid storage devices use two power mechanisms to establish positive and negative pressure, each power mechanism requires its own matching pipeline components, resulting in a large number of pipeline components and a complex structure, which in turn leads to higher production costs for the liquid storage devices. Summary of the Invention

[0004] To address the aforementioned technical problems, this application provides a liquid storage device and its control method, as well as a sample testing device.

[0005] To address the aforementioned problems, this application provides a first technical solution: a liquid storage device applied to a sample testing equipment, the liquid storage device comprising a reagent storage mechanism, a pressure storage mechanism, and a power mechanism; the reagent storage mechanism for storing reagents required for testing by the sample testing equipment; the pressure storage mechanism for providing positive pressure to the reagent storage mechanism; the inlet end of the power mechanism connected to the reagent storage mechanism via a first pipeline, and the outlet end of the power mechanism connected to the pressure storage mechanism via a second pipeline; wherein, when the first pipeline is open, the power mechanism provides negative pressure to the reagent storage mechanism, and / or, when the second pipeline is open, the power mechanism provides positive pressure to the pressure storage mechanism.

[0006] Optionally, the above-mentioned liquid storage device further includes a first control valve, the first control end of the first control valve being connected to the reagent storage mechanism via a fourth pipeline, the second control end of the first control valve being connected to the pressure storage mechanism via a third pipeline, and the third control end of the first control valve being connected to the inlet end of the power mechanism via the first pipeline.

[0007] Optionally, the above-mentioned liquid storage device further includes a second control valve. The first control end of the second control valve is connected to the outlet end of the power mechanism via the second pipeline, the second control end of the second control valve is connected to the pressure storage mechanism via the second pipeline, and the third control end of the second control valve is connected to an external air source via a fifth pipeline. The first control valve controls the opening of the first pipeline, the second control valve controls the opening of the second pipeline, the inlet end of the power mechanism provides negative pressure to the reagent storage mechanism, and the outlet end of the power mechanism provides positive pressure to the pressure storage mechanism. Alternatively, the first control valve controls the opening of the first pipeline, the second control valve controls the opening of the fifth pipeline, the inlet end of the power mechanism provides negative pressure to the reagent storage mechanism, and the outlet end of the power mechanism discharges the positive pressure to the external air source.

[0008] Optionally, the liquid storage device further includes a pressure sensor connected to the pressure storage mechanism. The pressure sensor is used to detect the current pressure of the pressure storage mechanism. When the current pressure of the pressure storage mechanism is greater than a first preset threshold, the second control valve is used to control the fifth pipeline to open. When the current pressure of the pressure storage mechanism is less than or equal to the first preset threshold, the second control valve is used to control the second pipeline to open.

[0009] Optionally, the liquid storage device further includes a liquid level sensor connected to the reagent storage mechanism. The liquid level sensor is used to detect the current liquid level of the reagent storage mechanism. When the current liquid level of the reagent storage mechanism is greater than a second preset threshold, the first control valve is used to control the third pipeline to open, so that the pressure storage mechanism provides positive pressure to the reagent storage mechanism. When the current liquid level of the reagent storage mechanism is less than or equal to the second preset threshold, the first control valve is used to control the first pipeline to open, and the inlet end of the power mechanism is used to provide negative pressure to the reagent storage mechanism, so that the reagent storage mechanism can replenish reagents under negative pressure.

[0010] Optionally, the above-mentioned liquid storage device further includes a third control valve. The first control end of the third control valve is connected to the inlet end of the power mechanism via a sixth pipeline, the second control end of the third control valve is connected to an external air source via the sixth pipeline, and the third control end of the third control valve is connected to a sealed air source via the sixth pipeline. The first control valve controls the opening of the first pipeline, and the third control valve controls the connection between the inlet end of the power mechanism and the sealed air source. The power mechanism draws gas from the reagent storage mechanism to provide negative pressure to the reagent storage mechanism. Alternatively, the first control valve controls the opening of the third pipeline, and the third control valve controls the connection between the inlet end of the power mechanism and the external air source. The power mechanism draws gas from the external air source and provides positive pressure to the pressure storage mechanism, so that the pressure storage mechanism provides positive pressure to the reagent storage mechanism.

[0011] Optionally, the above-mentioned liquid storage device further includes a filter, the second control terminal of the third control valve is connected to the first control terminal of the filter through the sixth pipeline, the second control terminal of the filter is connected to the external air source, and the filter is used to filter the gas from the external air source.

[0012] Optionally, the above-mentioned liquid storage device further includes an external reagent assembly and a fourth control valve. The first control end of the fourth control valve is connected to the reagent storage mechanism through a seventh pipeline, and the second control end of the fourth control valve is connected to the external reagent assembly through the seventh pipeline. In this case, the reagent storage mechanism is under the negative pressure, the fourth control valve is open, and the reagent in the external reagent assembly enters the reagent storage mechanism through the seventh pipeline under the negative pressure.

[0013] To address the aforementioned issues, this application provides a second technical solution: a sample testing device comprising the above-mentioned liquid storage device and liquid path support assembly, wherein the reagent storage mechanism of the liquid storage device is used to store the reagents required for testing; and the liquid path support assembly is used to transfer the reagents from the reagent storage mechanism to a preset liquid application site.

[0014] To address the aforementioned problems, this application provides a third technical solution: a control method for a liquid storage device, applied to the aforementioned liquid storage device. The control method includes: acquiring the current pressure of the pressure storage mechanism and the current liquid level of the reagent storage mechanism; when the current pressure is greater than a first preset threshold and the current liquid level is less than or equal to a second preset threshold, controlling the inlet end of the power mechanism to connect with the reagent storage mechanism and controlling the outlet end of the power mechanism to connect with an external air source to provide negative pressure to the reagent storage mechanism; when the current pressure is less than or equal to the first preset threshold and the current liquid level is less than or equal to the second preset threshold, controlling the inlet end of the power mechanism to connect with the reagent storage mechanism and controlling the outlet end of the power mechanism to connect with the pressure storage mechanism to provide negative pressure to the reagent storage mechanism and positive pressure to the pressure storage mechanism; when the current pressure is less than or equal to the first preset threshold and the current liquid level is greater than the second preset threshold, controlling the inlet end of the power mechanism to connect with the external air source and controlling the outlet end of the power mechanism to connect with the pressure storage mechanism to provide positive pressure to the pressure storage mechanism.

[0015] This application provides a liquid storage device and its control method, as well as a sample testing device. The liquid storage device includes a reagent storage mechanism, a pressure storage mechanism, and a power mechanism. The reagent storage mechanism stores reagents required for testing by the sample testing device. The pressure storage mechanism provides positive pressure to the reagent storage mechanism. The inlet of the power mechanism is connected to the reagent storage mechanism via a first pipeline, and the outlet of the power mechanism is connected to the pressure storage mechanism via a second pipeline. Specifically, when the first pipeline is open, the power mechanism provides negative pressure to the reagent storage mechanism, and / or, when the second pipeline is open, the power mechanism provides positive pressure to the pressure storage mechanism. The liquid storage device of this application can establish positive pressure using one port of the power mechanism, allowing the power mechanism to provide positive pressure to the pressure storage mechanism, thereby providing positive pressure to the reagent storage mechanism when connected to it, ensuring the normal operation of the reagent storage mechanism. Alternatively, it can also establish negative pressure using the other port of the power mechanism, allowing the power mechanism to provide negative pressure to the reagent storage mechanism, thus replenishing the liquid in the reagent storage mechanism. Therefore, the liquid storage device of this application reduces the use of piping components, has a simple structure, and effectively reduces the production cost of the liquid storage device. Attached Figure Description

[0016] To more clearly illustrate the technical solutions in the embodiments of this application, the accompanying drawings used in the description of the embodiments will be briefly introduced below. Obviously, the drawings described below are only some embodiments of this application. For those skilled in the art, other drawings can be obtained based on these drawings without creative effort. Wherein:

[0017] Figure 1 This is a schematic diagram of the structure of an embodiment of the liquid storage device provided in this application;

[0018] Figure 2 This is a schematic diagram of the structure of an embodiment of the sample detection device provided in this application;

[0019] Figure 3 This is a schematic flowchart of an embodiment of the control method for the liquid storage device provided in this application.

[0020] Among them, 10 is the liquid storage device; 11 is the reagent storage mechanism; 12 is the pressure storage mechanism; 13 is the power mechanism; 14 is the first control valve; 15 is the second control valve; 16 is the third control valve; 17 is the fourth control valve; 18 is the pressure sensor; 19 is the filter; 20 is the external reagent assembly; 30 is the liquid circuit support assembly; 40 is the detection assembly; and 50 is the sample preparation assembly. Detailed Implementation

[0021] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of this application, and not all embodiments. Based on the embodiments of this application, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this application.

[0022] It should be noted that if the embodiments of this application involve directional indicators (such as up, down, left, right, front, back, etc.), the directional indicators are only used to explain the relative positional relationship and movement of the components in a certain specific posture (as shown in the figure). If the specific posture changes, the directional indicators will also change accordingly.

[0023] Furthermore, if the embodiments of this application involve descriptions such as "first" or "second," these descriptions are for descriptive purposes only and should not be construed as indicating or implying their relative importance or implicitly specifying the number of technical features indicated. Therefore, features defined with "first" or "second" may explicitly or implicitly include at least one of those features. Additionally, the technical solutions of various embodiments can be combined with each other, but this must be based on the ability of those skilled in the art to implement them. If the combination of technical solutions is contradictory or impossible to implement, it should be considered that such a combination of technical solutions does not exist and is not within the scope of protection claimed in this application.

[0024] Please see Figure 1 , Figure 1 This is a schematic diagram of an embodiment of the liquid storage device provided in this application. Figure 1As shown, the liquid storage device 10 is applied to a sample testing device, which is an analytical device used to test samples such as blood, urine, and feces. For example, the sample testing device can be a blood cell analyzer, a blood analyzer, a urine analyzer, etc. The liquid storage device 10 is used to provide reagent support for the sample testing device to ensure the normal operation of the sample testing device.

[0025] The liquid storage device 10 includes a reagent storage mechanism 11, a pressure storage mechanism 12, and a power mechanism 13. The reagent storage mechanism 11 is used to store reagents required for the sample detection equipment. The pressure storage mechanism 12 is used to provide positive pressure to the reagent storage mechanism 11. The inlet end of the power mechanism 13 is connected to the reagent storage mechanism 11 through a first pipeline, and the outlet end of the power mechanism 13 is connected to the pressure storage mechanism 12 through a second pipeline. Wherein, when the first pipeline is open, the power mechanism 13 is used to provide negative pressure to the reagent storage mechanism 11, and / or when the second pipeline is open, the power mechanism 13 is used to provide positive pressure to the pressure storage mechanism 12.

[0026] Specifically, the reagents stored in the reagent storage mechanism 11 can be changed based on the detection requirements of the sample testing equipment. For example, the reagents in the reagent storage mechanism 11 can be, but are not limited to, diluents, cleaning solutions, hemolysins, eluents, and other reagents required for testing. The pressure storage mechanism 12 provides positive pressure to the reagent storage mechanism 11 by storing positive pressure. The power mechanism 13 can be, but is not limited to, air pumps, air compressors, and other components that can generate positive and negative pressure by compressing air.

[0027] The inlet of the power mechanism 13 is connected to the reagent storage mechanism 11 via a first pipeline, and the outlet of the power mechanism 13 is connected to the pressure storage mechanism 12 via a second pipeline. Therefore, when the first pipeline is open, a negative pressure is generated at the inlet of the power mechanism 13, resulting in negative pressure within the reagent storage mechanism 11. Under this negative pressure, the reagent storage mechanism 11 can draw reagents from other components and replenish them, ensuring that the reagent quantity in the reagent storage mechanism 11 meets the requirements of the sample detection equipment. When the second pipeline is open, a positive pressure is generated at the outlet of the power mechanism 13, resulting in positive pressure within the pressure storage mechanism 12. When the reagent storage mechanism 11 and the pressure storage mechanism 12 are connected, the reagent storage mechanism 11 can utilize the positive pressure of the pressure storage mechanism 12 to transfer its reagents to other components of the sample detection equipment under positive pressure.

[0028] Understandably, the aforementioned first and / or second pipeline connection can specifically include the following situations: The first pipeline between the reagent storage mechanism 11 and the power mechanism 13 is connected, whereby the inlet of the power mechanism 13 draws gas from the reagent storage mechanism 11, creating a negative pressure within the reagent storage mechanism 11, and the outlet of the power mechanism 13 can discharge the drawn gas to the liquid storage device 10 or other parts of the sample detection equipment; the second pipeline between the pressure storage mechanism 12 and the power mechanism 13 is connected, whereby the inlet of the power mechanism 13 draws gas from the liquid storage device 10 or other parts of the sample detection equipment. The gas in other parts of the preparation is discharged through the outlet end to the pressure storage mechanism 12, so that positive pressure is generated in the pressure storage mechanism 12; the first pipeline between the reagent storage mechanism 11 and the power mechanism 13 and the second pipeline between the pressure storage mechanism 12 and the power mechanism 13 are connected. The inlet end of the power mechanism 13 draws gas from the reagent storage mechanism 11 and discharges it through the outlet end of the power mechanism 13 to the pressure storage mechanism 12, so that negative pressure is generated in the reagent storage mechanism 11 during the operation of the power mechanism 13, and positive pressure is simultaneously replenished to the pressure storage mechanism 12.

[0029] In this embodiment, the liquid storage device 10 can establish positive pressure using one port of the power mechanism 13, allowing the power mechanism 13 to provide positive pressure to the pressure storage mechanism 12. This positive pressure is then provided to the reagent storage mechanism 11 via the connection between the pressure storage mechanism 12 and the reagent storage mechanism 11, ensuring the normal operation of the reagent storage mechanism 11. Alternatively, a negative pressure can be established using the other port of the power mechanism 13, allowing the power mechanism 13 to provide negative pressure to the reagent storage mechanism 11, thus replenishing the liquid in the reagent storage mechanism 11. Therefore, the liquid storage device 10 in this embodiment can achieve both negative pressure supply to the reagent storage mechanism 11 and positive pressure replenishment to the pressure storage mechanism 12 through a single power mechanism 13, reducing the use of piping components, simplifying the structure, and effectively reducing the production cost of the liquid storage device 10.

[0030] In one embodiment, the liquid storage device 10 further includes a first control valve 14. The first control end of the first control valve 14 is connected to the reagent storage mechanism 11 through a fourth pipeline, the second control end of the first control valve 14 is connected to the pressure storage mechanism 12 through a third pipeline, and the third control end of the first control valve 14 is connected to the inlet end of the power mechanism 13 through a first pipeline.

[0031] Specifically, the first control valve 14 is a valve control device with one inlet and two outlets. The first control end of the first control valve 14 is the inlet, and the second and third control ends of the first control valve 14 are the outlets. The first control valve 14 is used to switch the gas connection pipeline of the reagent storage mechanism 11. The first control valve 14 can be used to control the reagent storage mechanism 11 to be connected to the power mechanism 13 through the first pipeline to provide negative pressure to the reagent storage mechanism 11. Alternatively, the first control valve 14 can also be used to control the reagent storage mechanism 11 to be connected to the pressure storage mechanism 12 through the third pipeline to provide positive pressure to the reagent storage mechanism 11.

[0032] In the above manner, the liquid storage device 10 of this embodiment can be switched by the control of the first control valve 14 to provide positive and negative pressure to the reagent storage mechanism 11 through a power mechanism 13, which can effectively reduce the use of pipeline components, simplify the structure, and further reduce the production cost of the liquid storage device 10.

[0033] Optionally, the liquid storage device 10 further includes a second control valve 15. The first control end of the second control valve 15 is connected to the outlet end of the power mechanism 13 through a second pipeline, the second control end of the second control valve 15 is connected to the pressure storage mechanism 12 through a second pipeline, and the third control end of the second control valve 15 is connected to an external air source through a fifth pipeline.

[0034] The second control valve 15 is a valve control device with one inlet and two outlets. The first control end of the second control valve 15 is the inlet, and the second and third control ends are the outlets. The second control valve 15 is used to switch the pipeline at the outlet end of the power mechanism 13 so that the gas drawn in by the power mechanism 13 can be discharged through the outlet end to the pressure storage mechanism 12 or the external air source. Here, the external air source can be understood as an open gas environment at normal atmospheric pressure.

[0035] In one embodiment, a first control valve 14 controls the opening of a first pipeline, a second control valve 15 controls the opening of a second pipeline, the inlet of the power mechanism 13 provides negative pressure to the reagent storage mechanism 11, and the outlet of the power mechanism 13 provides positive pressure to the pressure storage mechanism 12. Specifically, the power mechanism 13 can utilize the negative pressure resources established during operation to provide negative pressure to the reagent storage mechanism 11, allowing the reagent storage mechanism 11 to replenish reagents using negative pressure, and utilize the positive pressure resources established during operation to provide positive pressure to the pressure storage mechanism 12, allowing the pressure storage mechanism 12 to serve as a positive pressure reserve for the reagent storage mechanism 11, facilitating the subsequent provision of positive pressure to the reagent storage mechanism 11. Through this method, the utilization rate of the power mechanism 13 can be significantly improved, enabling the power mechanism 13 to simultaneously meet the negative and positive pressure requirements of the liquid storage device 10, reducing resource waste and further lowering the operating cost of the liquid storage device 10.

[0036] In another embodiment, the first control valve 14 is used to control the opening of the first pipeline, the second control valve 15 is used to control the opening of the fifth pipeline, the inlet end of the power mechanism 13 is used to provide negative pressure to the reagent storage mechanism 11, and the outlet end of the power mechanism 13 is used to discharge positive pressure to the outside air source. Specifically, when the pressure of the pressure storage mechanism 12 meets the usage requirements, that is, when the current pressure of the pressure storage mechanism 12 is greater than the first preset threshold, the first control valve 14 can control the opening of the first pipeline, and the second control valve 15 can control the opening of the fifth pipeline, so that the power mechanism 13 can discharge the gas absorbed by the reagent storage mechanism 11 to the outside air source, ensuring the negative pressure environment of the reagent storage mechanism 11 while reducing the impact of the positive pressure generated by the power mechanism 13 on other components, and improving the reliability of the liquid storage device 10.

[0037] In other embodiments, when the reagent storage mechanism 11 does not require reagent replenishment and the positive pressure of the pressure storage mechanism 12 is sufficient, the first pipeline can be opened by the first control valve 14, so that the reagent storage mechanism 11 is in a positive pressure environment, which can effectively reduce the gas evolution in the reagent of the reagent storage mechanism 11, reduce or avoid the generation of bubbles, and improve the reliability of the reagent storage mechanism 11.

[0038] Furthermore, the liquid storage device 10 also includes a pressure sensor 18, which is connected to the pressure storage mechanism 12 and is used to detect the current pressure of the pressure storage mechanism 12. When the current pressure of the pressure storage mechanism 12 is greater than a first preset threshold, the second control valve 15 is used to control the fifth pipeline to open; when the current pressure of the pressure storage mechanism 12 is less than or equal to the first preset threshold, the second control valve 15 is used to control the second pipeline to open.

[0039] Specifically, in this embodiment, the pressure sensor 18 can monitor the current pressure of the pressure storage mechanism 12. When the current pressure of the pressure storage mechanism 12 is greater than a first preset threshold, it is determined that the positive pressure environment of the pressure storage mechanism 12 can provide positive pressure support for the reagent storage mechanism 11. The first control valve 14 is used to control the opening of the first pipeline, and the second control valve 15 is used to control the opening of the fifth pipeline, so that the positive pressure generated by the power mechanism 13 can be discharged to the external air source. When the current pressure of the pressure storage mechanism 12 is less than or equal to the first preset threshold, it is determined that the positive pressure of the pressure storage mechanism 12 is insufficient, and the pressure storage mechanism 12 needs to be supplemented with positive pressure. The first control valve 14 is used to control the opening of the first pipeline, and the second control valve 15 is used to control the opening of the second pipeline, so that the positive pressure generated by the power mechanism 13 can supplement the pressure storage mechanism 12. The first preset threshold for pressure of the pressure storage mechanism 12 can be selected based on the reagent dispensing amount, reagent dispensing frequency, dispensing speed, reagent type, etc. of the reagent storage mechanism 11, and is not specifically limited here.

[0040] In the above manner, the pressure sensor 18 can ensure that the pressure storage mechanism 12 is stable in a preset positive pressure environment, so as to provide positive pressure support for the reagent storage mechanism 11 and avoid the positive pressure of the pressure storage mechanism 12 being too high due to excessive positive pressure replenishment, which would affect the accuracy of subsequent sample detection equipment when calling the positive pressure of the pressure storage mechanism 12.

[0041] Furthermore, the liquid storage device 10 also includes a liquid level sensor connected to the reagent storage mechanism 11. The liquid level sensor is used to detect the current liquid level of the reagent storage mechanism 11. In one embodiment, the liquid level sensor includes, but is not limited to, a float-type liquid level sensor, a pressure-type liquid level sensor, a capacitive liquid level sensor, a photoelectric liquid level sensor, an ultrasonic liquid level sensor, etc., to detect the liquid level of the reagent storage mechanism 11. In another embodiment, the liquid level sensor can also obtain the current liquid level of the reagent storage mechanism 11 by measuring the volume of the reagent storage mechanism 11 and converting the volume into the liquid level of the reagent storage mechanism 11. The specific principle of liquid level detection is not limited here.

[0042] When the current liquid level of the reagent storage mechanism 11 is greater than the second preset threshold, the first control valve 14 is used to control the opening of the third pipeline so that the pressure storage mechanism 12 provides positive pressure to the reagent storage mechanism 11; when the current liquid level of the reagent storage mechanism 11 is less than or equal to the second preset threshold, the first control valve 14 is used to control the opening of the first pipeline, and the inlet end of the power mechanism 13 is used to provide negative pressure to the reagent storage mechanism 11 so that the reagent storage mechanism 11 can replenish reagents under negative pressure.

[0043] Specifically, in this embodiment, the current liquid level of the reagent storage mechanism 11 can be monitored by a liquid level sensor. When the current liquid level of the reagent storage mechanism 11 is greater than a second preset threshold, meaning the current liquid level of the reagent storage mechanism 11 can meet the current reagent usage requirements, the first control valve 14 is used to control the opening of the third pipeline, so that the pressure storage mechanism 12 is connected to the reagent storage mechanism 11, allowing the reagent storage mechanism 11 to transfer reagents to other liquid-using parts of the sample detection equipment under positive pressure. When the current liquid level of the reagent storage mechanism 11 is less than or equal to the second preset threshold, meaning the amount of reagent in the reagent storage mechanism 11 is insufficient to meet the current reagent usage requirements, the first control valve 14 is used to control the opening of the first pipeline, so that the power mechanism 13 can provide negative pressure to the reagent storage mechanism 11 and allow the reagent storage mechanism 11 to replenish reagents under negative pressure. The second preset threshold for the liquid level of the reagent storage mechanism 11 can be selected based on the amount of reagent used by the reagent storage mechanism 11, the frequency of reagent use, the detection items of the sample detection equipment, and the detection requirements, etc., and is not specifically limited here.

[0044] Optionally, the liquid storage device 10 also includes a third control valve 16. The first control end of the third control valve 16 is connected to the inlet end of the power mechanism 13 through a sixth pipeline, the second control end of the third control valve 16 is connected to an external air source through a sixth pipeline, and the third control end of the third control valve 16 is connected to a sealed air source through a sixth pipeline.

[0045] Understandably, the aforementioned closed air source can be understood as a closed gas environment. For example, a closed gas environment can be formed at the third control terminal of the third control valve 16 by blocking the third control terminal with a mechanical component; or, the closed device can be connected to the third control terminal of the third control valve 16 through a sixth pipeline, so that the third control terminal of the third control valve 16, the sixth pipeline, and the closed device together form a closed gas environment. No specific limitations are made on the structure for forming the closed air source here.

[0046] The first control valve 14 is used to control the opening of the first pipeline, and the third control valve 16 is used to control the inlet end of the power mechanism 13 to be connected to the sealed air source. The power mechanism 13 is used to draw gas from the reagent storage mechanism 11 to provide negative pressure to the reagent storage mechanism 11. The first control valve 14 is used to control the opening of the third pipeline, and the third control valve 16 is used to control the inlet end of the power mechanism 13 to be connected to the external air source. The power mechanism 13 is used to draw gas from the external air source and provide positive pressure to the pressure storage mechanism 12 so that the pressure storage mechanism 12 provides positive pressure to the reagent storage mechanism 11.

[0047] Specifically, the third control valve 16 is a valve control device with one inlet and two outlets. The first control end of the third control valve 16 is the inlet, and the second and third control ends are the outlets. The third control valve 16 is used to switch the inlet pipeline of the power mechanism 13. When the first and second control ends of the third control valve 16 are connected, the power mechanism 13 can draw gas from the external air source through the inlet end, so that the outlet end of the power mechanism 13 can provide positive pressure to the pressure storage mechanism 12. Alternatively, when the first and third control ends of the third control valve 16 are connected, since the third control end of the third control valve 16 is connected to the sealed air source, the inlet end of the power mechanism 13 cannot draw gas from the sealed air source. Therefore, the power mechanism 13 can draw gas from the reagent storage mechanism 11 through the inlet end to provide negative pressure to the reagent storage mechanism 11.

[0048] Through the above method, the liquid storage device 10 of this embodiment can switch the third control valve 16 so that the power mechanism 13 can selectively draw gas from the external air source or the reagent storage mechanism 11, so that the liquid storage device 10 can independently provide negative pressure to the reagent storage mechanism 11 and positive pressure to the pressure storage mechanism 12, making the liquid storage device 10 of this embodiment applicable to a variety of usage scenarios and effectively improving the practicality of the liquid storage device 10.

[0049] Furthermore, the liquid storage device 10 also includes a filter 19. The second control terminal of the third control valve 16 is connected to the first control terminal of the filter 19 through a sixth pipeline. The second control terminal of the filter 19 is connected to an external air source. The filter 19 is used to filter the gas from the external air source.

[0050] Specifically, filter 19 can be used to remove dust, foreign matter, and other impurities from the external air source to ensure the quality of the gas drawn in by the power mechanism 13 through the inlet, reduce or avoid wear and tear on components such as pipelines, valves, and pumps due to air impurities, and improve the service life and reliability of the liquid storage device 10. The filter 19 can be, but is not limited to, a mechanical filter 19, an adsorption filter 19, a particulate filter 19, or a composite filtration system. The selection of filter 19 can be based on the operating environment of the liquid storage device 10 and the sample testing equipment, and no specific limitations are made here.

[0051] In one embodiment, the liquid storage device 10 further includes an external reagent assembly 20 and a fourth control valve 17. The first control end of the fourth control valve 17 is connected to the reagent storage mechanism 11 through a seventh pipeline, and the second control end of the fourth control valve 17 is connected to the external reagent assembly 20 through a seventh pipeline. When the reagent storage mechanism 11 is under negative pressure, the fourth control valve 17 is open, and the reagent in the external reagent assembly 20 enters the reagent storage mechanism 11 through the seventh pipeline under the action of negative pressure.

[0052] Specifically, the fourth control valve 17 is a valve device with one inlet and one outlet. The first control end of the fourth control valve 17 is connected to the reagent storage mechanism 11 through the seventh pipeline, and the second control end of the fourth control valve 17 is connected to the external reagent assembly 20 through the seventh pipeline. When the fourth control valve 17 is turned on, the reagent in the external reagent assembly 20 enters the reagent storage mechanism 11 through the seventh pipeline under the negative pressure of the reagent storage mechanism 11, so as to replenish the reagent storage mechanism 11.

[0053] Understandably, when the current liquid level of the reagent storage mechanism 11 is monitored by the liquid level sensor, when the current liquid level of the reagent storage mechanism 11 is less than or equal to the second preset threshold, the first control valve 14 controls the first pipeline to open, the fourth control valve 17 controls the fourth control valve to open, and the power component to work, so that the reagent storage mechanism 11 is under negative pressure and the reagent of the external reagent component 20 can enter the reagent storage mechanism 11 through the seventh pipeline.

[0054] Therefore, the liquid storage device 10 in this embodiment can provide negative pressure to the reagent storage device 11 through the power mechanism 13 and control the pipeline connection between the reagent storage device 11 and the external reagent assembly 20 to achieve reagent replenishment of the reagent storage device 11. The method is simple and easy to implement, and can effectively reduce the assembly difficulty and production cost of the liquid storage device 10.

[0055] In one embodiment, the first, second, third, fourth, fifth, and sixth pipelines mentioned above are all gas pipelines. The first, second, third, fourth, fifth, sixth, and seventh pipelines defined above are only used to indicate the pipeline positions between various components. The pipelines of the first, second, third, fourth, fifth, and sixth pipelines may partially overlap or be set independently, and no specific limitation is made here.

[0056] In one embodiment, the pressure storage mechanism 12 of the liquid storage device 10 of this embodiment can also provide a positive pressure environment for other components, which is not specifically limited here.

[0057] This application also provides a sample detection device; please refer to [link to relevant documentation]. Figure 2 , Figure 2 This is a schematic diagram of the structure of one embodiment of the sample detection device provided in this application. Figure 2 As shown, the sample testing device includes a liquid path support component 30 and a liquid storage device 10 as described in any of the above embodiments. The reagent storage mechanism 11 of the liquid storage device 10 is used to store the reagents required for testing. The liquid path support component 30 is used to transfer the reagents from the reagent storage mechanism 11 to a preset liquid application site.

[0058] Specifically, the preset liquid application areas include, but are not limited to, the detection area of ​​the sample detection device, the tubing components related to the detection area, and the components related to sample collection, transfer, and sample preparation. For example, the sample detection device may also include a detection component 40, which is connected to a liquid path support component 30. When the pressure storage mechanism 12 provides positive pressure to the reagent storage mechanism 11, the liquid path support component 30 can be used to provide the reagents from the reagent storage mechanism 11 to the detection area for use. The sample detection device may also include a sample preparation component 50, which is connected to the liquid path support component 30. When the pressure storage mechanism 12 provides positive pressure to the reagent storage mechanism 11, the liquid path support component 30 can be used to provide the reagents from the reagent storage mechanism 11 to the sample preparation component 50, so that sample preparation, cleaning, and other steps can be performed within the sample preparation component 50.

[0059] This application also provides a sample testing device, which includes an external reagent assembly and a liquid storage device 10 as described in any of the above embodiments. The reagent storage mechanism 11 of the liquid storage device 10 is connected to the external reagent assembly via a seventh pipeline. The external reagent assembly is used to store the reagents required for testing and replenishes the reagents to the reagent storage mechanism 11 via the seventh pipeline. The reagent storage capacity of the external reagent assembly is greater than the reagent storage capacity of the reagent storage mechanism 11; for example, the external reagent assembly can be a reagent container, a large-capacity reagent pool, etc.

[0060] Specifically, the detection component 40 is connected to the reagent storage mechanism 11 via a liquid path support component 30. The liquid path support component 30 provides reagents from the reagent storage mechanism 11 to the detection area of ​​the detection component 40, enabling the detection component 40 to perform detection on the sample. When the reagent level in the reagent storage mechanism 11 is insufficient, the fourth control valve 17 can be opened to allow reagents from the external reagent component to enter the reagent storage mechanism 11 through the seventh pipeline, replenishing the reagents and ensuring that the detection component 40 can continuously perform detection.

[0061] This application also provides a control method for the liquid storage device 10. Please refer to [link to relevant documentation]. Figure 3 , Figure 3 This is a schematic flowchart of an embodiment of the control method for the liquid storage device provided in this application. Figure 3 As shown, the control method of this embodiment may include the following steps:

[0062] Step S10: Obtain the current pressure of the pressure storage mechanism 12 and the current liquid level of the reagent storage mechanism 11.

[0063] Specifically, the reagent storage mechanism 11 is used to store the reagents required for the test, and the current liquid level of the reagent storage mechanism 11 is used to indicate the amount of reagent liquid in the reagent storage mechanism 11; the pressure storage mechanism 12 is used to store positive pressure gas and provide pressure to the reagent storage mechanism 11, and the current pressure of the pressure storage mechanism 12 can be used to indicate the pressure intensity of the positive pressure gas in the pressure storage mechanism 12.

[0064] Step S20: When the current pressure is greater than the first preset threshold and the current liquid level is less than or equal to the second preset threshold, control the inlet end of the power mechanism 13 to be connected to the reagent storage mechanism 11, and control the outlet end of the power mechanism 13 to be connected to the external air source to provide negative pressure for the reagent storage mechanism 11.

[0065] When the current pressure is greater than the first preset threshold, it means that the positive pressure environment of the pressure storage mechanism 12 can provide positive pressure support for the reagent storage mechanism 11, and the pressure storage mechanism 12 does not need to be replenished with positive pressure. However, since the current liquid level is less than or equal to the second preset threshold, the reagent quantity in the reagent storage mechanism 11 is insufficient to meet the current reagent usage requirements, and the reagent storage mechanism 11 needs to be replenished. At this time, by controlling the inlet end of the power mechanism 13 to be connected to the reagent storage mechanism 11 and controlling the outlet end of the power mechanism 13 to be connected to an external air source, negative pressure can be provided to the reagent storage mechanism 11 without affecting the pressure environment of the pressure storage mechanism 12. Therefore, the negative pressure environment of the reagent storage mechanism 11 can be guaranteed while reducing the impact of the positive pressure generated by the power mechanism 13 on the pressure storage mechanism 12, thus improving the reliability of the liquid storage device 10.

[0066] Step S30: When the current pressure is less than or equal to the first preset threshold and the current liquid level is less than or equal to the second preset threshold, control the inlet end of the power mechanism 13 to be connected to the reagent storage mechanism 11, and control the outlet end of the power mechanism 13 to be connected to the pressure storage mechanism 12, so as to provide negative pressure to the reagent storage mechanism 11 and positive pressure to the pressure storage mechanism 12.

[0067] Specifically, when the current pressure is less than or equal to a first preset threshold and the current liquid level is less than or equal to a second preset threshold, it indicates that the pressure storage mechanism 12 needs positive pressure replenishment and the reagent storage mechanism 11 needs reagent replenishment. At this time, by controlling the inlet of the power mechanism 13 to connect with the reagent storage mechanism 11 and the outlet of the power mechanism 13 to connect with the pressure storage mechanism 12, negative pressure can be provided to the reagent storage mechanism 11 for reagent replenishment while positive pressure replenishment is provided to the pressure storage mechanism 12. Therefore, the utilization rate of the power mechanism 13 can be significantly improved, enabling the power mechanism 13 to simultaneously meet the negative and positive pressure requirements of the liquid storage device 10, reducing resource waste and further lowering the operating cost of the liquid storage device 10.

[0068] Step S40: When the current pressure is less than or equal to the first preset threshold and the current liquid level is greater than the second preset threshold, control the inlet end of the power mechanism 13 to be connected to the external air source, and control the outlet end of the power mechanism 13 to be connected to the pressure storage mechanism 12, so as to provide positive pressure to the pressure storage mechanism 12.

[0069] When the current pressure is less than or equal to the first preset threshold and the current liquid level is greater than the second preset threshold, it means that the pressure storage mechanism 12 needs to be replenished with positive pressure and the reagent storage mechanism 11 does not need to be replenished with reagents. At this time, the inlet end of the power mechanism 13 can be connected to the external air source, and the outlet end of the power mechanism 13 can be connected to the pressure storage mechanism 12, so as to provide positive pressure to the pressure storage mechanism 12 without affecting the pressure environment of the reagent storage mechanism 11, thus ensuring the normal use of the reagent storage mechanism 11.

[0070] In this embodiment, the control method of the liquid storage device 10 can control the conduction status of the power mechanism 13 under different conditions of the pressure storage mechanism 12 and the reagent storage mechanism 11. For example, when the pressure storage mechanism 12 needs positive pressure replenishment, the power mechanism 13 can be controlled to provide positive pressure to the pressure storage mechanism 12 alone; when the reagent storage mechanism 11 needs reagent replenishment, the power mechanism 13 can be controlled to provide negative pressure to the reagent storage mechanism 11 alone; and when both the pressure storage mechanism 12 and the reagent storage mechanism 11 need replenishment, the power mechanism 13 can be controlled to provide positive pressure to the pressure storage mechanism 12 and negative pressure to the reagent storage mechanism 11 simultaneously. Therefore, the control method is diverse, making the liquid storage device 10 applicable to various usage scenarios and effectively improving the practicality of the liquid storage device 10.

[0071] The above description is merely an embodiment of this application and does not limit the patent scope of this application. Any equivalent structural or procedural transformations made using the content of this application's specification and drawings, or direct or indirect applications in other related technical fields, are similarly included within the patent protection scope of this application.

Claims

1. A liquid storage device, characterized by, The liquid storage device, used in sample testing equipment, includes: A reagent storage facility for storing reagents required for the sample detection equipment. A pressure storage mechanism for providing positive pressure to the reagent storage mechanism; The power mechanism has its inlet end connected to the reagent storage mechanism via a first pipeline, and its outlet end connected to the pressure storage mechanism via a second pipeline. Wherein, the first pipeline is open, and the power mechanism is used to provide negative pressure to the reagent storage mechanism, and / or, the second pipeline is open, and the power mechanism is used to provide positive pressure to the pressure storage mechanism.

2. The liquid storage device of claim 1, wherein, The liquid storage device further includes a first control valve, the first control end of which is connected to the reagent storage mechanism via a fourth pipeline, the second control end of which is connected to the pressure storage mechanism via a third pipeline, and the third control end of which is connected to the inlet end of the power mechanism via the first pipeline.

3. The liquid storage device according to claim 2, characterized in that, The liquid storage device further includes a second control valve, the first control end of which is connected to the outlet end of the power mechanism through the second pipeline, the second control end of which is connected to the pressure storage mechanism through the second pipeline, and the third control end of which is connected to an external air source through the fifth pipeline. Wherein, the first control valve is used to control the opening of the first pipeline, the second control valve is used to control the opening of the second pipeline, the inlet end of the power mechanism is used to provide negative pressure to the reagent storage mechanism, and the outlet end of the power mechanism is used to provide positive pressure to the pressure storage mechanism; or, the first control valve is used to control the opening of the first pipeline, the second control valve is used to control the opening of the fifth pipeline, the inlet end of the power mechanism is used to provide negative pressure to the reagent storage mechanism, and the outlet end of the power mechanism is used to discharge the positive pressure to the external air source.

4. The liquid storage device according to claim 3, characterized in that, The liquid storage device also includes a pressure sensor connected to the pressure storage mechanism, which is used to detect the current pressure of the pressure storage mechanism. When the current pressure of the pressure storage mechanism is greater than a first preset threshold, the second control valve is used to control the fifth pipeline to open; When the current pressure of the pressure storage mechanism is less than or equal to the first preset threshold, the second control valve is used to control the second pipeline to open.

5. The liquid storage device according to claim 3, characterized in that, The liquid storage device also includes a liquid level sensor, which is connected to the reagent storage mechanism and is used to detect the current liquid level of the reagent storage mechanism. When the current liquid level in the reagent storage mechanism is greater than the second preset threshold, the first control valve is used to control the third pipeline to open, so that the pressure storage mechanism provides positive pressure to the reagent storage mechanism; When the current liquid level of the reagent storage mechanism is less than or equal to the second preset threshold, the first control valve is used to control the opening of the first pipeline, and the inlet end of the power mechanism is used to provide negative pressure to the reagent storage mechanism so that the reagent storage mechanism can replenish reagents under negative pressure.

6. The liquid storage device according to claim 2, characterized in that, The liquid storage device also includes a third control valve. The first control end of the third control valve is connected to the inlet end of the power mechanism through a sixth pipeline. The second control end of the third control valve is connected to an external air source through the sixth pipeline. The third control end of the third control valve is connected to a sealed air source through the sixth pipeline. Wherein, the first control valve is used to control the opening of the first pipeline, and the third control valve is used to control the inlet end of the power mechanism to be connected to the sealed air source. The power mechanism is used to draw gas from the reagent storage mechanism to provide negative pressure to the reagent storage mechanism; the first control valve is used to control the opening of the third pipeline, and the third control valve is used to control the inlet end of the power mechanism to be connected to the external air source. The power mechanism is used to draw gas from the external air source and provide positive pressure to the pressure storage mechanism, so that the pressure storage mechanism provides positive pressure to the reagent storage mechanism.

7. The liquid storage device according to claim 6, characterized in that, The liquid storage device also includes a filter. The second control terminal of the third control valve is connected to the first control terminal of the filter through the sixth pipeline. The second control terminal of the filter is connected to the external air source. The filter is used to filter the gas from the external air source.

8. The liquid storage device according to claim 1, characterized in that, The liquid storage device also includes an external reagent assembly and a fourth control valve. The first control end of the fourth control valve is connected to the reagent storage mechanism through a seventh pipeline, and the second control end of the fourth control valve is connected to the external reagent assembly through the seventh pipeline. The reagent storage mechanism is under negative pressure, the fourth control valve is open, and the reagent from the external reagent assembly enters the reagent storage mechanism through the seventh pipeline under the negative pressure.

9. A sample testing device, characterized in that, include: The liquid storage device according to any one of claims 1-8, wherein the reagent storage mechanism of the liquid storage device is used to store reagents required for detection; A liquid flow support component is used to transfer reagents from the reagent storage mechanism to a preset liquid application site.

10. A control method for a liquid storage device, characterized in that, The control method, applied to the liquid storage device as described in any one of claims 1-8, comprises: Obtain the current pressure of the pressure storage mechanism and the current liquid level of the reagent storage mechanism; When the current pressure is greater than a first preset threshold and the current liquid level is less than or equal to a second preset threshold, the inlet end of the power mechanism is connected to the reagent storage mechanism, and the outlet end of the power mechanism is connected to an external air source to provide negative pressure to the reagent storage mechanism. When the current pressure is less than or equal to a first preset threshold and the current liquid level is less than or equal to a second preset threshold, the inlet end of the power mechanism is connected to the reagent storage mechanism, and the outlet end of the power mechanism is connected to the pressure storage mechanism, so as to provide negative pressure to the reagent storage mechanism and positive pressure to the pressure storage mechanism. When the current pressure is less than or equal to a first preset threshold and the current liquid level is greater than a second preset threshold, the inlet end of the power mechanism is connected to the external air source, and the outlet end of the power mechanism is connected to the pressure storage mechanism to provide positive pressure to the pressure storage mechanism.

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