A portable point-of-care device

Abstract

The application provides a portable instant inspection device, comprising: a shell for accommodating and protecting internal components; a temperature control bin for accommodating a sample to be measured and maintaining temperature; a temperature control unit for adjusting the temperature of the temperature control bin; a sample flow channel connected with the temperature control bin for inputting the sample to be measured into the temperature control bin; a detection sensor for detecting the concentration of substances in the sample to be measured; a control unit for processing feedback signals of the temperature control unit and the detection sensor; and a display screen for displaying detection data of the temperature control bin and the detection sensor; the control unit collects and processes signals from the detection sensor interface in real time, and calculates and updates the concentration-time curve and numerical value displayed on the display screen in real time based on the processed signals, so that the application can quickly, accurately and timely detect the concentration of substances in blood in a non-laboratory environment such as a bedside or a site.

Description

Technical Field

[0001] This invention relates to the field of medical testing technology, specifically to a portable point-of-care testing device. Background Technology

[0002] Currently, the most commonly used methods for lactate detection in hospitals rely on the analysis of ex vivo blood samples, specifically through automated biochemical analyzers or blood gas analyzers. While these methods offer high accuracy, they have several significant limitations: First, they require in vitro blood collection, and the process of sample transport, pretreatment, and analysis must be performed by professionals, making it cumbersome and time-consuming. Second, ex vivo samples are susceptible to changes in temperature, time, and operating conditions during storage and transportation, which can alter lactate concentrations and affect the accuracy of results. Third, this method is intermittent and cannot achieve continuous, dynamic monitoring of lactate levels, making it difficult to provide immediate data support for real-time assessment and treatment adjustments in critically ill patients.

[0003] In addition, electrochemical sensor technology based on lactate dehydrogenase catalysis can also be used for lactate detection, which relies on enzymatic reactions to convert lactate into an electrochemical signal. Although this method has potential advantages such as device miniaturization and fast detection speed, a series of problems still exist in practical clinical applications: enzyme activity is easily affected by environmental factors, and the stability and lifespan of the sensor face challenges; the detection process usually still requires manual intervention for sample introduction and signal reading, making it difficult to integrate into continuous monitoring systems; at the same time, repeatability, anti-interference ability, and integration with existing hospital information systems still need further optimization.

[0004] In summary, existing lactate detection technologies generally suffer from common shortcomings such as reliance on in vitro sampling, complex detection procedures, long processing times, and inability to achieve real-time continuous monitoring, which restrict their application in the medical field for real-time dynamic monitoring. Summary of the Invention

[0005] The present invention was made to solve the above-mentioned problems, and its purpose is to provide a portable point-of-care testing device.

[0006] This invention provides a portable point-of-care testing device, characterized by: a housing for housing and protecting internal components; a temperature control chamber disposed inside the housing for containing and maintaining the temperature of the sample to be tested; a temperature control unit disposed on the temperature control chamber for regulating the temperature of the temperature control chamber; a sample flow channel disposed inside the housing and connected to the temperature control chamber for inputting the sample to be tested into the temperature control chamber; a detection sensor disposed inside the housing and connected to the temperature control chamber for detecting the concentration of the substance in the sample; a control unit disposed on the housing and electrically connected to the temperature control chamber and the detection sensor for processing the feedback signals from the temperature control unit and the detection sensor; and a display screen disposed on the housing and connected to the control unit for displaying the detection data from the temperature control chamber and the detection sensor; the control unit acquires and processes signals from the detection sensor interface in real time, and calculates and updates the concentration-time curve and values ​​displayed on the display screen in real time based on the processed signals.

[0007] The portable point-of-care testing device provided by this invention may also have the following features: the temperature control unit includes: a heating unit disposed on the temperature control chamber for heating the temperature control chamber; a cooling unit disposed on the temperature control chamber for cooling the temperature control chamber; a heat dissipation unit disposed on the housing for dissipating heat from the cooling unit; a circulation pump disposed on the temperature control chamber and connected to the heating unit and the cooling unit respectively, for uniformly delivering the heat generated by the heating unit or the cold generated by the cooling unit to each part of the temperature control chamber to avoid local overheating or overcooling; and a temperature sensor disposed on the temperature control chamber for detecting the temperature of the temperature control chamber.

[0008] The portable instant testing device provided by the present invention may also have the following feature: wherein the temperature control unit generates control commands based on the preset target temperature value and the current temperature value fed back in real time by the temperature control chamber, and dynamically controls the working state of the heating unit or cooling unit and the heat dissipation unit, so that the temperature value in the temperature control chamber is stabilized within the range of the preset target temperature value ±1℃.

[0009] The portable point-of-care testing device provided by the present invention may also have the following features: wherein the heat dissipation unit includes: a heat sink, which is attached to the hot end of the cooling unit and is used to absorb the heat from the hot end of the cooling unit; and a heat exchange fan, which is connected to the heat sink and is used to dissipate the heat from the heat sink.

[0010] The portable point-of-care testing device provided by this invention may also have the following features: the heat transfer components of the heating unit, cooling unit, and circulating pump that are in contact with the fluid are made of copper or aluminum; the main frame of the shell is made of POM material, and the observation window is made of optically transparent material.

[0011] The portable point-of-care testing device provided by this invention may also include the following features: a sealing ring disposed on the housing for isolating the internal and external environments of the device; a sealing gasket disposed on the housing and connected to the sealing ring for cooperating with the sealing ring to isolate the internal and external environments of the device; and a waste liquid box detachably disposed inside the housing and connected to the sample flow channel for collecting the test sample after testing.

[0012] The portable point-of-care testing device provided by the present invention may also have the following features: a transparent glass plate is provided on the top of the housing, a temperature control chamber is located in the center of the housing, a temperature control unit is provided on the side of the housing and connected to the temperature control chamber, a control unit is provided on the other side of the housing, a temperature display screen is provided on the top of the housing, a waste liquid box is provided in the groove on the front of the housing, and a sealing ring and a sealing gasket are stacked on the top of the temperature control chamber.

[0013] The portable point-of-care testing device provided by this invention may also include the following features: physical buttons, disposed on the housing and connected to the display screen and the control unit respectively, for receiving user commands and transmitting them to the control unit; wherein the physical buttons include: a detection button, a delete button, a batch delete button and a data export button.

[0014] The portable point-of-care testing device provided by this invention may also have the following features: the control unit captures the original electrical signal through the sensor interface, and performs constant potential control, filtering, amplification and analog-to-digital conversion on the original electrical signal in sequence; based on the digital signal after analog-to-digital conversion, the concentration value of the substance to be tested is calculated according to a preset calibration curve or algorithm, and the display screen is controlled to display the concentration value in real time; when the concentration value of the substance to be tested exceeds a preset threshold, the display screen will issue an alarm prompt.

[0015] The portable point-of-care testing device provided by the present invention may also have the following feature: wherein the substance concentration values ​​of the sample to be tested are lactic acid concentration value and potassium ion concentration value.

[0016] The role and effect of invention

[0017] According to the present invention, a portable point-of-care testing device includes: a housing for housing and protecting internal components; a temperature control chamber disposed inside the housing for containing and maintaining the temperature of the sample to be tested; a temperature control unit disposed on the temperature control chamber for regulating the temperature of the temperature control chamber; a sample flow channel disposed inside the housing and connected to the temperature control chamber for inputting the sample to be tested into the temperature control chamber; a detection sensor disposed inside the housing and connected to the temperature control chamber for detecting the concentration of substances in the sample to be tested; a control unit disposed on the housing and electrically connected to the temperature control chamber and the detection sensor for processing the feedback signals from the temperature control unit and the detection sensor; and a display screen disposed on the housing and connected to the control unit for displaying the detection data from the temperature control chamber and the detection sensor. The control unit acquires and processes signals from the detection sensor interface in real time, and calculates and updates the concentration-time curve and values ​​displayed on the display screen in real time based on the processed signals. Therefore, the portable point-of-care testing device of the present invention can rapidly, accurately, and in real time detect the concentration of substances in blood in non-laboratory environments such as at the bedside or in the field. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the structure of a portable point-of-care testing device in an embodiment of the present invention.

[0019] Figure 2 This is a schematic diagram of the portable point-of-care testing device from another direction in an embodiment of the present invention.

[0020] Figure 3 This is a schematic diagram of the housing in an embodiment of the present invention.

[0021] Figure 4 This is a schematic diagram of the internal structure of the portable point-of-care testing device in an embodiment of the present invention.

[0022] Figure 5 This is a schematic diagram of the sealing ring in an embodiment of the present invention.

[0023] Figure 6 This is a schematic diagram of the sealing gasket structure in an embodiment of the present invention.

[0024] Figure 7 This is a schematic diagram of the display interface of the screen in an embodiment of the present invention. Detailed Implementation

[0025] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication between two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0026] To make the technical means, creative features, objectives and effects of the present invention easy to understand, the following embodiments, in conjunction with the accompanying drawings, provide a detailed description of a portable instant testing device of the present invention.

[0027] Example

[0028] Figure 1 This is a schematic diagram of the structure of a portable point-of-care testing device in an embodiment of the present invention.

[0029] Figure 2 This is a schematic diagram of the portable point-of-care testing device from another direction in an embodiment of the present invention.

[0030] like Figure 1 and Figure 2 As shown, this embodiment provides a portable point-of-care testing device 100, including: a housing 1, a temperature control chamber 2, a temperature control unit 3, a sample flow channel 4, a detection sensor 5, a control unit 6, a display screen 7, a sealing ring 8, a sealing gasket 9, a waste liquid box 10, and physical buttons 11.

[0031] Figure 3 This is a schematic diagram of the housing in an embodiment of the present invention.

[0032] like Figure 3 As shown, housing 1 is used to house and protect internal components. In this embodiment, the main frame of housing 1 is made of POM material, and the observation window is made of optically transparent material. The external dimensions are: length 310mm, width 200mm, height 145mm, and total weight 6.5kg.

[0033] Temperature control chamber 2 is located inside shell 1 and is used to contain the sample to be tested and maintain its temperature. Temperature control chamber 2 is a cubic cavity used to place the sample to be tested.

[0034] In this embodiment, the concentration values ​​of the sample to be tested are the lactic acid concentration and the potassium ion concentration. The corresponding detection sensor 5 can be replaced according to the detection requirements to achieve the detection of different substance concentrations.

[0035] Figure 4This is a schematic diagram of the internal structure of the portable point-of-care testing device in an embodiment of the present invention.

[0036] like Figure 4 As shown, the temperature control unit 3 is installed on the temperature control chamber 2 and is used to adjust the temperature of the temperature control chamber 2.

[0037] The temperature control unit 3 includes: a heating unit 31, a cooling unit 32, a heat dissipation unit 33, a circulating pump 34, and a temperature sensor 35.

[0038] The heating unit 31 is disposed on the temperature control chamber 2 and is used to heat the temperature control chamber 2. In this embodiment, the heating unit 31 is a magnesium-aluminum heating rod.

[0039] A cooling unit 32 is disposed on the temperature control chamber 2 and is used to cool the temperature control chamber 2. In this embodiment, the cooling unit 32 is a semiconductor cooling chip.

[0040] The heat dissipation unit 33 is disposed on the housing 1 and is used to dissipate heat from the cooling unit 32.

[0041] The heat dissipation unit 33 includes: heat sink 331 and heat exchange fan 332.

[0042] The heat sink 331 is attached to the hot end of the cooling unit 32 to absorb the heat from the hot end of the cooling unit 32.

[0043] The heat exchange fan 332 is connected to the heat sink 331 and is used to dissipate the heat from the heat sink 331. In this embodiment, the heat exchange fan 332 is a rugged fan.

[0044] A circulating pump 34 is disposed on the side of the temperature control chamber 2 and is connected to both the heating unit 31 and the cooling unit 32. It is used to evenly distribute the heat generated by the heating unit 31 or the cold energy generated by the cooling unit 32 to all parts of the temperature control chamber 2, preventing localized overheating or overcooling. In this embodiment, the circulating pump 34 is a silent peristaltic pump. The fluid in the circulating pump 34 is antifreeze.

[0045] Temperature sensor 35 is installed on temperature control chamber 2 to detect the temperature of temperature control chamber 2. Temperature control unit 3 generates control commands based on preset target temperature value and the current temperature value fed back by temperature control chamber 2 in real time, and dynamically controls the working state of heating unit 31 or cooling unit 32 and heat dissipation unit 33 to stabilize the temperature value in temperature control chamber 2 within the range of preset target temperature value ±1℃.

[0046] Among them, the heat transfer components of the heating unit 31, the cooling unit 32 and the circulating pump 34 that are in contact with the fluid are made of copper or aluminum.

[0047] The sample flow channel 4 is located inside the housing 1 and connected to the temperature control chamber 2, used to input the sample to be tested into the temperature control chamber 2. The sample flow channel 4 is also connected to the waste liquid box 10, used to discharge the sample after testing.

[0048] In this embodiment, a peristaltic pump and a microfluidic chip are provided in the sample flow channel 4. The sample to be tested is continuously drawn into the reaction chamber of the microfluidic chip, and the microcurrent generated by the enzyme reaction is transmitted to the control unit 6 for reading through the electrodes and circuit of the detection sensor 5.

[0049] The detection sensor 5 is located inside the housing 1 and connected to the temperature control chamber 2. Specifically, it is mounted on the microfluidic chip in the sample flow channel 4 and is used to detect the concentration of substances in the sample. In this embodiment, the detection sensor 5 is a lactate dehydrogenase electrochemical sensor. The detection sensor 5 converts the chemical reaction into a measurable electrical signal through electrodes. The detection sensor 5 can be replaced according to the detection requirements.

[0050] The control unit 6 is mounted on the housing and is electrically connected to the temperature control chamber 2 and the detection sensor 5. It is used to process the feedback signals from the temperature control unit 3 and the detection sensor 5.

[0051] In this embodiment, the control unit 6 is a circuit board, programmed in C language, debugged and verified according to actual needs, and integrated with the equipment operation process. Simultaneously developed application software (APP) can display the substance concentration in real time on the display screen 7. It can also accumulate test batches and has data export functionality.

[0052] The display screen 7 is mounted on the housing 1 and connected to the control unit 6. It is used to display the detection data of the temperature control chamber 2 and the detection sensor 5.

[0053] The control unit 6 collects and processes signals from the interface of the detection sensor 5 in real time, and calculates and updates the concentration-time curve and values ​​displayed on the display screen 7 in real time based on the processed signals.

[0054] The control unit 6 captures the original electrical signal through the interface of the detection sensor 5, and performs constant potential control, filtering, amplification and analog-to-digital conversion on the original electrical signal in sequence.

[0055] Based on the digital signal after analog-to-digital conversion, the concentration value of the substance to be tested is calculated according to the preset calibration curve or algorithm, and the display screen 7 is controlled to display the concentration value in real time. When the concentration value of the substance to be tested exceeds the preset threshold, the display screen 7 will issue an alarm prompt.

[0056] Figure 5 This is a schematic diagram of the sealing ring in an embodiment of the present invention.

[0057] Figure 6This is a schematic diagram of the sealing gasket structure in an embodiment of the present invention.

[0058] like Figure 5 and Figure 6 As shown, the sealing ring 8 is disposed on the housing 1 to isolate the internal and external environments of the equipment. The sealing ring 8 is a square air cushion with a cavity inside.

[0059] A sealing gasket 9 is disposed on the housing 1 and connected to the sealing ring 8, used to cooperate with the sealing ring 9 to isolate the internal and external environments of the equipment. In this embodiment, the sealing ring 8 and the sealing gasket 9 can achieve an IP68 level of environmental contamination, facilitating storage, transportation and use in harsh environments.

[0060] The waste liquid box 10 is detachably installed inside the housing 1 and connected to the sample flow channel 4 for collecting the test sample after the test is completed.

[0061] The housing 1 includes a transparent glass cover 1a on top, which isolates the housing 1 from the outside world without obstructing the view. A temperature control chamber 2 is located at the center of the housing 1. A temperature control unit 3 is located on the side of the housing 1 and connected to the temperature control chamber 2. A control unit 6 is located on the other side of the housing 1. A temperature display screen 7 is located on the top of the housing 1. A waste liquid container 10 is located in a groove on the front of the housing 1. Two limiting buckles 1b are also provided on the front of the housing 1, which are used to fix the waste liquid container 10 in the groove by rotation. The limiting buckles 1b use miniature bearings and neodymium magnet magnetic positioning structures. The housing 1 also has a power interface and a USB interface 1c for connecting an external power source to supply power and transmit data to the entire portable point-of-care testing device 100. A sealing ring 8 and a sealing gasket 9 are stacked on top of the temperature control chamber 2.

[0062] Physical buttons 11 are disposed on the housing 1 and connected to the display screen 7 and the control unit 6 respectively, for receiving user commands and transmitting them to the control unit 6. In this embodiment, the physical buttons 11 include: a detection button, a delete button, a batch delete button, and a data export button.

[0063] When the housing 1 or the transparent glass cover 1a becomes dirty, it should be cleaned and wiped with a neutral cleaning agent.

[0064] Before using the portable point-of-care testing device 100 again after long-term storage, a check should be performed, including checking whether all bolts are loose (the recommended torque for re-tightening during the check is 1.2 Nm), wiping all gaps in the device with a clean paper towel, and checking for liquid stains. If the stains have an alcohol odor, further inspection of the internal pipelines is required to check for leaks.

[0065] After prolonged storage, the portable point-of-care testing device 100 needs to be powered on for verification before reuse to check whether the device software and screen can be opened and operated normally. It also needs to be powered on to check whether each button functions properly.

[0066] The antifreeze of the portable point-of-care testing device 100 should be changed at least once a year. When changing the antifreeze, first loosen the large cover plate on the housing 1, pump in the new antifreeze (75% alcohol and pure water mixture, 550mL recommended), and pump out the old liquid. After the filling is completed, reconnect the pipeline, install the large cover plate, and tighten it to a torque of 1.2N·m.

[0067] The working principle of the portable point-of-care testing device 100 is as follows: After the sample to be tested is input, the portable point-of-care testing device 100 is powered on and operates autonomously. The peristaltic pump in the sample flow channel 4 continuously draws the sample into the reaction chamber of the microfluidic chip. The microcurrent generated by the enzyme reaction is transmitted to the control unit 6 for reading through the electrodes and circuit of the detection sensor 5. The circulation pump 34 starts to circulate the antifreeze continuously, raising or lowering the temperature according to the preset temperature target. When a temperature increase is needed, the heating unit 31 starts to work, working with the antifreeze driven by the circulation pump 34 to uniformly raise the temperature of the device, gradually approaching the target temperature. When a cooling is needed, the cooling unit 32 and the heat dissipation unit 33 are turned on simultaneously, exchanging the heat energy of the cooling unit 32 with the outside environment. To ensure the lifespan of the cooling unit 32, the device has a cooling protection system. The temperature sensor 35 detects the temperature in real time and uploads the temperature value to the display screen 7 for the user to view.

[0068] Figure 7 This is a schematic diagram of the display interface of the screen in an embodiment of the present invention.

[0069] like Figure 7 As shown, after the device is powered on, the display screen 7 first shows the startup screen. After the startup screen ends, a data coordinate graph, as well as the data and status bars below, are displayed. During startup detection, data changes will be visually displayed in the data coordinate graph. In this embodiment, the measured substance concentrations are potassium ion concentration and lactic acid concentration. Below the data coordinate graph, there are numerical bars for potassium ion and lactic acid, allowing the user to visually see the data values. When the lactic acid concentration or potassium ion concentration exceeds the threshold, an alarm is triggered. The device also has physical buttons 11. When the detection button is pressed, the device will perform a detection and display the result on the screen. When the delete button is pressed, the device will delete the previous detection result. When the batch delete button is pressed, the device will delete the data in the current batch. When the data export button is pressed, the locally stored data will be sent to the host computer.

[0070] The role and effect of the embodiments

[0071] A portable point-of-care testing device according to this embodiment includes: a housing for housing and protecting internal components; a temperature control chamber disposed inside the housing for housing the sample to be tested and maintaining its temperature; a temperature control unit disposed on the temperature control chamber for adjusting the temperature of the temperature control chamber; a sample flow channel disposed inside the housing and connected to the temperature control chamber for inputting the sample to be tested into the temperature control chamber; a detection sensor disposed inside the housing and connected to the temperature control chamber for detecting the concentration of substances in the sample to be tested; a control unit disposed on the housing and electrically connected to the temperature control chamber and the detection sensor for processing the feedback signals from the temperature control unit and the detection sensor; and a display screen disposed on the housing and connected to the control unit for displaying the detection data from the temperature control chamber and the detection sensor. The control unit acquires and processes signals from the detection sensor interface in real time, and calculates and updates the concentration-time curve and values ​​displayed on the display screen in real time based on the processed signals. Therefore, the portable point-of-care testing device of this invention can rapidly, accurately, and in real time detect the concentration of substances in blood in non-laboratory environments such as at the bedside or on-site.

[0072] This portable point-of-care testing device simplifies the complex biochemical testing process into a minimally invasive operation: simply place the sample and press the button to test. By integrating temperature control, detection, and display into one unit, and providing clearly defined physical function keys, it significantly reduces the operational threshold and reliance on professional personnel, enabling non-laboratory staff to quickly and reliably complete tests.

[0073] The portable point-of-care testing device in this embodiment also has data storage and export functions. Users can view the results on-site and also upload historical data to the host computer via the data export button, which facilitates the formation of electronic records, long-term trend analysis, or inclusion in the medical information system, solving the problem of traditional bedside testing data being difficult to save and manage.

[0074] This embodiment adopts a modular structure, which meets the maintenance requirements for long-term use and extends the service life and reliability of the equipment in harsh environments.

[0075] This embodiment also uses a combination of sealing rings and sealing gaskets to achieve an IP68-level structural seal.

[0076] Those skilled in the art should understand that this invention is not limited to the above embodiments. The embodiments and descriptions in the specification are merely illustrative of the principles of the invention. Various changes and modifications can be made to this invention without departing from its spirit and scope, and all such changes and modifications fall within the scope of the invention as claimed. The scope of protection of this invention is defined by the appended claims and their equivalents.

Claims

1. A portable point-of-care device, characterized in that, include: A housing, used to contain and protect internal components; A temperature control chamber, located inside the housing, is used to contain the sample to be tested and maintain its temperature; A temperature control unit is disposed on the temperature control chamber and is used to adjust the temperature of the temperature control chamber; A sample flow channel, located inside the housing and connected to the temperature control chamber, is used to input the sample to be tested into the temperature control chamber. A detection sensor, located inside the housing and connected to the temperature control chamber, is used to detect the concentration of substances in the sample to be tested. A control unit, disposed on the housing, is electrically connected to the temperature control chamber and the detection sensor, and is used to process the feedback signals from the temperature control unit and the detection sensor; A display screen, mounted on the housing and connected to the control unit, is used to display the detection data of the temperature control chamber and the detection sensor; The control unit acquires and processes signals from the detection sensor interface in real time, and calculates and updates the concentration-time curve and values ​​displayed on the screen in real time based on the processed signals.

2. The portable point-of-care testing device according to claim 1, characterized in that, in, The temperature control unit includes: A heating unit is installed on the temperature control chamber and is used to heat the temperature control chamber; A refrigeration unit is installed on the temperature control chamber and is used to refrigerate the temperature control chamber. A heat dissipation unit is disposed on the housing and is used to dissipate heat from the cooling unit; A circulating pump is installed on the temperature control chamber and connected to the heating unit and the cooling unit respectively. It is used to evenly transport the heat generated by the heating unit or the cold generated by the cooling unit to each part of the temperature control chamber to avoid local overheating or overcooling. A temperature sensor is installed on the temperature control chamber to detect the temperature of the temperature control chamber.

3. The portable point-of-care testing device according to claim 2, characterized in that: in, The temperature control unit generates control commands based on the preset target temperature value and the current temperature value fed back in real time by the temperature control chamber, and dynamically controls the working state of the heating unit or the cooling unit and the heat dissipation unit, so that the temperature value in the temperature control chamber is stabilized within the range of the preset target temperature value ±1℃.

4. The portable point-of-care testing device according to claim 2, Its features are: The heat dissipation unit includes: A heat sink is attached to the hot end of the cooling unit to absorb heat from the hot end of the cooling unit. A heat exchange fan, connected to the heat sink, is used to dissipate the heat from the heat sink.

5. The portable point-of-care testing device according to claim 2, characterized in that: in, The heat transfer components of the heating unit, the cooling unit, and the circulating pump that are in contact with the fluid are made of copper or aluminum. The main frame of the housing is made of POM material, and the observation window is made of optically transparent material.

6. The portable point-of-care testing device according to claim 1, characterized in that, Also includes: A sealing ring is provided on the housing to isolate the internal and external environments of the equipment; A sealing gasket is disposed on the housing and connected to the sealing ring, and is used to cooperate with the sealing ring to isolate the internal and external environments of the equipment. The waste liquid box is detachably installed inside the housing and connected to the sample flow channel for collecting the test sample after the test is completed.

7. The portable point-of-care testing device according to claim 1, characterized in that: in, The top of the housing is also provided with a transparent glass plate. The temperature control chamber is located in the center of the housing. The temperature control unit is located on the side of the housing and connected to the temperature control chamber. The control unit is located on the other side of the housing. The temperature display screen is located on the top of the housing. The waste liquid box is located in the groove on the front of the housing. The sealing ring and the sealing gasket are stacked on the top of the temperature control chamber.

8. The portable point-of-care testing device according to claim 1, characterized in that, Also includes: Physical buttons are disposed on the housing and connected to the display screen and the control unit respectively, for receiving user commands and transmitting them to the control unit; wherein, the physical buttons include: a detection button, a delete button, a batch delete button, and a data export button.

9. The portable point-of-care testing device according to claim 8, Its features are: The control unit captures the original electrical signal through the detection sensor interface and performs constant potential control, filtering, amplification and analog-to-digital conversion on the original electrical signal in sequence. Based on the digital signal after analog-to-digital conversion, the concentration value of the substance in the sample to be tested is calculated according to a preset calibration curve or algorithm, and the display screen is controlled to display the concentration value in real time. When the concentration value of the substance in the sample to be tested exceeds a preset threshold, the display screen will issue an alarm.

10. The portable point-of-care testing device according to claim 9, characterized in that: in, The concentration values ​​of the substances in the sample to be tested are lactic acid concentration and potassium ion concentration.

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