Hydrogel two-component just-mix-inject device for repairing diabetic foot

Abstract

The embodiment of the application provides a hydrogel two-component preparation device for repairing diabetic foot, and relates to the field of medical equipment. The device comprises a mixing and conveying mechanism and a pressure coating mechanism. The pressure coating mechanism is installed at one end of the mixing and conveying mechanism. The mixing and conveying mechanism can convey the gel two-component to the pressure coating mechanism while mixing. The pressure coating mechanism is controlled to shrink the volume of the inner cavity, so that the internal gel is extruded. The mixing and conveying mechanism comprises a conveying cylinder, a first motor, an auger and an outlet. The first motor is installed at the end of the conveying cylinder. The auger is rotatably installed in the conveying cylinder, and one end of the auger is connected with the output end of the first motor. The outlet is installed at the end of the conveying cylinder away from the first motor. The device can ensure that the mixing and injection can be achieved every time, and there is no excessive mixed raw material remaining in the device. In addition, the device can realize multi-gear control and ensure that the second baffle is limited after being pressed.

Description

Technical Field

[0001] This invention relates to the field of pharmaceutical equipment, specifically to a two-component instant-mixing and instant-injection preparation device for diabetic foot repair using hydrogel. Background Technology

[0002] Diabetes is closely related to infection, which is one of its major complications. Studies have confirmed that diabetes significantly increases the risk of infection-related hospitalizations, with foot infections, exemplified by diabetic foot ulcers, being particularly prominent. Diabetic foot ulcers are chronic wounds caused by multiple factors. Peripheral neuropathy and arterial disease are the main early pathological manifestations, both of which reduce tissue repair and anti-infection capabilities, creating a vicious cycle of poor wound healing. This, coupled with factors such as abnormal enzyme activity, oxidative stress, and bacterial infection, leads to prolonged wound non-healing. In clinical treatment, ideal dressings are crucial for the healing of diabetic wounds.

[0003] Currently, using hydrogel as a dressing is the most common method. However, the current application equipment usually involves feeding the mixed hydrogel into the extrusion applicator. This method typically requires pre-mixing a certain amount of hydrogel, making it impossible to mix and apply immediately. If the remaining hydrogel remains for too long, it will affect the cleanliness of subsequent applications.

[0004] Based on this, the present invention is proposed. Summary of the Invention

[0005] According to embodiments of the present invention, a two-component, instant-mixing and injectable hydrogel preparation device for diabetic foot repair is provided. This addresses the problems existing in the prior art.

[0006] In a first aspect of the present invention, a two-component instant-mixing and instant-injection preparation device for hydrogel repair of diabetic foot is provided.

[0007] The device for preparing a two-component hydrogel for diabetic foot repair includes a mixing and conveying mechanism and a pressing and coating mechanism. The pressing and coating mechanism is installed at one end of the mixing and conveying mechanism, which can deliver the two-component hydrogel to the pressing and coating mechanism and mix them at the same time. The pressing and coating mechanism is controlled and can shrink the inner cavity volume to extrude the internal hydrogel. The mixing mechanism includes: a conveying cylinder, a first motor, an auger, and an outlet; The first motor is installed at the end of the conveying cylinder; the auger is rotatably installed inside the conveying cylinder, and one end of it is connected to the output end of the first motor; the outlet is installed at the end of the conveying cylinder away from the first motor. The pressure coating mechanism includes: a first baffle, an inlet, a material hopper, a second baffle, an application port, a first through groove, a second through groove, a limiting strip, and a locking tooth; The insertion port is located on the first baffle; the outlet is inserted into the insertion port; one side of the hopper is installed on one side of the first baffle; the second baffle is installed on the other side of the hopper; the application port is located on the side of the second baffle away from the hopper; the first through groove and the second through groove are respectively located on the second baffle and the first baffle, and they correspond to each other; one end of the limiting strip is rotatably installed in the first through groove, and the other end passes through the second through groove; there are several locking teeth, which are equidistantly installed on the side of the limiting strip away from the hopper; the locking teeth engage with the second through groove.

[0008] Preferably, the pressure coating mechanism further includes: a slide bar and a spring; The two ends of the slide rod slide through the first baffle and the second baffle respectively. There are two slide rods, which are symmetrically arranged with respect to the hopper. The spring is sleeved on the slide rod and is located between the first baffle and the second baffle.

[0009] Preferably, the pressure coating mechanism further includes: a slot, a sleeve, and a slider; The slot is formed on the outer wall of one end of the conveying cylinder, and the slot is an L-shaped device; the sleeve is slidably installed at the end of the conveying cylinder; the slider is installed on the inner wall of the sleeve, and the slider is slidably installed in the slot; the first baffle is rotatably installed on the sleeve.

[0010] Preferably, the coating mechanism further includes: a straight surface, an inclined surface, and a clamping surface; The locking teeth are arranged in right-angled triangles, with one side perpendicular to the limiting strip forming a straight surface and the other side inclined relative to the limiting strip forming a slope. The edge of the second through groove forms a locking surface, and the straight surface engages with the locking surface.

[0011] Preferably, the coating mechanism further includes: a leaf spring and a limiting buckle; The leaf spring is installed in the second through groove; the limiting buckle is installed on the outer wall of the sleeve, and the leaf spring is located inside the limiting buckle.

[0012] Preferably, the limiting strip is inclined outward from the first through groove towards the second through groove.

[0013] Preferably, the outlet is provided with a one-way valve, and the discharge direction of the one-way valve is towards the side away from the conveying cylinder.

[0014] Preferably, it also includes: a feeding mechanism; The feeding mechanism is installed at the end of the mixing and conveying mechanism away from the coating mechanism, and is used to push the gel two-component raw material into the mixing and conveying mechanism.

[0015] Preferably, the feeding mechanism includes: a connecting frame, a feeding pipe, a material cylinder, a cylinder cover, a first gear, a second gear, a second motor, a lead screw, a limiting groove, a push plate, a connecting plate, and a top plate; The connecting frame is installed at the end of the conveying cylinder away from the coating mechanism; there are two feeding pipes, one end of which is connected to the connecting frame and the other end of which is connected to the conveying cylinder; there are two cylinder covers, which are rotatably connected to the lower surface of the top plate; there are two material cylinders, the bottom end of which is placed on the top of the connecting frame and extends into the two feeding pipes; the two cylinder covers are screwed to the top ends of the two material cylinders; there are two first gears, which are rotatably installed on the upper surface of the top plate and mesh with each other; the second gear is rotatably installed on the upper surface of the top plate and meshes with one of the first gears; the second motor is installed on the lower surface of the top plate and the output end of the second motor is connected to the second gear; there are two lead screws, which are screwed to the two first gears respectively, and the bottom end of the lead screw extends into the material cylinder; the limiting groove is axially formed on the lead screw; the top plate is provided with a protrusion adapted to the limiting groove and the protrusion is installed in the limiting groove; the push plate is installed at the bottom end of the lead screw.

[0016] Preferably, the feeding mechanism further includes a blocking component; the blocking component includes: a rotating shaft, a cover plate, a torsion spring, and a mounting block; The mounting block is installed at the bottom end of the material cylinder, and the rotating shaft is rotatably connected to the mounting block; the cover plate is installed on the rotating shaft; and the torsion spring is installed between the cover plate and the mounting block.

[0017] One or more technical solutions provided in this application have at least the following technical effects or advantages: 1. The present invention provides a two-component instant-mix and instant-injection preparation device for diabetic foot repair using hydrogel. By pressing the second baffle, the hydrogel in the hopper can be squeezed out and applied to the affected area through the application port. Furthermore, through the cooperation of the locking teeth and the locking surface, multiple control can be achieved to ensure that the second baffle is limited after being pressed, so that the second baffle remains in a fixed state after being pressed, avoiding air backflow that may affect the subsequent medication effect.

[0018] 2. The feeding mechanism in this invention can separately feed the two hydrogel raw materials into the mixing mechanism. At the same time, the mixing mechanism mixes the raw materials and achieves directional conveying, thereby ensuring that all the mixed hydrogel is sent into the pressure coating mechanism, ensuring that it can be mixed and injected immediately each time it is used, and that there will be no excessive mixed raw material residue inside the equipment.

[0019] It should be understood that the description in the Summary of the Invention is not intended to limit the key or essential features of the embodiments of the present invention, nor is it intended to restrict the scope of the invention. Other features of the invention will become readily apparent from the following description. Attached Figure Description

[0020] The above and other features, advantages, and aspects of the various embodiments of the present invention will become more apparent from the accompanying drawings and the following detailed description. In the drawings, the same or similar reference numerals denote the same or similar elements, wherein: Figure 1 A schematic diagram of the structure of a two-component instant-mix and instant-injection preparation device for diabetic foot repair according to an embodiment of the present invention is shown; Figure 2 An exploded structural diagram of a two-component instant-mix and instant-injection preparation device for diabetic foot repair according to an embodiment of the present invention is shown. Figure 3 An exploded structural diagram of a two-component instant-mix and instant-injection preparation device for diabetic foot repair according to an embodiment of the present invention is shown from another direction. Figure 4 A side view of a two-component instant-mix and instant-injection preparation device for diabetic foot repair according to an embodiment of the present invention is shown. Figure 5 A bottom view of the feeding mechanism of a two-component instant-mix and instant-injection preparation device for diabetic foot repair hydrogel according to an embodiment of the present invention is shown. Figure 6 A top cross-sectional view of the pressure coating mechanism of a two-component instant-mix and instant-injection preparation device for diabetic foot repair hydrogel according to an embodiment of the present invention is shown. Figure 7 A cross-sectional view of the feeding mechanism of a two-component instant-mix and instant-injection preparation device for diabetic foot repair hydrogel according to an embodiment of the present invention is shown. Figure 8 An enlarged view of section A is shown of a two-component instant-mix and instant-injection preparation device for diabetic foot repair according to an embodiment of the present invention. Figure 9 A magnified view at point B shows a two-component instant-mix and instant-injection preparation device for diabetic foot repair hydrogel according to an embodiment of the present invention. Figure 10 A magnified view at point C is shown of a two-component instant-mix and injectable hydrogel preparation device for diabetic foot repair according to an embodiment of the present invention.

[0021] The attached figures are labeled as follows: 1. Conveying cylinder; 2. First motor; 3. Screw; 4. Outlet; 5. Slot; 6. Sleeve; 7. Slider; 8. First baffle; 9. Insert; 10. Hopper; 11. Second baffle; 12. Slide rod; 13. Spring; 14. Application port; 15. First through groove; 16. Second through groove; 17. Limiting strip; 18. Clamping tooth; 19. Straight surface; 20. Inclined surface; 21. Clamping surface; 22. Leaf spring; 23. Limiting buckle; 24. Connecting frame; 25. Feed pipe; 26. Cylinder; 27. Cylinder cover; 28. First gear; 29. ​​Second gear; 30. Second motor; 31. Lead screw; 32. Limiting groove; 33. Push plate; 34. Connecting plate; 35. Top plate; 36. Rotating shaft; 37. Cover plate; 38. Torsion spring; 39. Mounting block. Detailed Implementation

[0022] To make the objectives, technical solutions, and advantages of the embodiments of the present invention clearer, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only some embodiments of the present invention, and not all embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of the present invention.

[0023] Furthermore, the term "and / or" in this article is merely a description of the relationship between related objects, indicating that three relationships can exist. For example, A and / or B can represent: A existing alone, A and B existing simultaneously, or B existing alone. Additionally, the character " / " in this article generally indicates that the preceding and following related objects have an "or" relationship.

[0024] like Figure 1 and Figure 2 As shown, this hydrogel two-component instant mixing and dispensing preparation device for diabetic foot repair includes: a mixing and conveying mechanism, a pressing and coating mechanism, and a feeding mechanism. The pressing and coating mechanism is installed at one end of the mixing and conveying mechanism, which simultaneously delivers the internal hydrogel two-components to the pressing and coating mechanism for mixing. The pressing and coating mechanism is used to temporarily store the mixed gel. The pressing and coating mechanism is controlled and can shrink its internal volume, thereby extruding the internal gel for application to the affected area. The feeding mechanism is installed at the end of the mixing and conveying mechanism away from the pressing and coating mechanism, and is used to push the hydrogel two-component raw material into the mixing and conveying mechanism.

[0025] refer to Figure 1 , Figure 2 , Figure 3 and Figure 4The mixing and conveying mechanism includes: a conveying cylinder 1, a first motor 2, an auger 3, and an outlet 4. The conveying cylinder 1 is a cylindrical hollow structure. The first motor 2 is installed at the end of the conveying cylinder 1. The auger 3 is rotatably installed inside the conveying cylinder 1, with one end connected to the output end of the first motor 2. Turning on the first motor 2 drives the auger 3 to rotate around its own axis, thereby achieving directional movement of the material. When the hydrogel bicomponent is injected into the conveying cylinder 1, the auger 3's rotation achieves mixing and directional conveying of the hydrogel. The outlet 4 is installed at the end of the conveying cylinder 1 furthest from the first motor 2. It is worth noting that in this embodiment, the method of driving the auger 3 is not limited to using the first motor 2; one end of the auger 3 extends out of the conveying cylinder 1 and is configured in a spline shape. In use, the auger 3 can be manually driven to rotate without using the first motor 2 by rotating this spline.

[0026] refer to Figure 1 , Figure 2 , Figure 3 , Figure 6 , Figure 8 and Figure 9The coating mechanism includes: a slot 5, a sleeve 6, a slider 7, a first baffle 8, an insertion port 9, a material hopper 10, a second baffle 11, a sliding rod 12, a spring 13, a coating port 14, a first through groove 15, a second through groove 16, a limiting strip 17, a locking tooth 18, a straight surface 19, an inclined surface 20, a locking surface 21, a leaf spring 22, and a limiting buckle 23. The slot 5 is located on the outer wall of one end of the conveying cylinder 1. The slot 5 is L-shaped, with a long groove along the axial direction of the conveying cylinder 1, a short groove connected to the long groove and along the circumference of the conveying cylinder 1, and the long groove opening towards one end of the conveying cylinder 1. The sleeve 6 is slidably mounted on the end of the conveying cylinder 1. The slider 7 is mounted on the inner wall of the sleeve 6 and slidably mounted within the slot 5. The sleeve 6 slides along the axial direction of the conveying cylinder 1 at its end. During this time, the slider 7 slides into the long slot of the slot 5. Then, the sleeve 6 is rotated, causing the slider 7 to slide into the short slot of the slot 5. At this point, the sleeve 6 is limited and will not move along the axial direction of the conveying cylinder 1 and fall off. The first baffle 8 is rotatably mounted on the sleeve 6, and the insertion port 9 is opened on the first baffle 8. The outlet 4 can be inserted into the insertion port 9. The outlet 4 is equipped with a one-way valve, and the discharge direction of the one-way valve is towards the side away from the conveying cylinder 1. One side of the hopper 10 is installed on the side of the first baffle 8 away from the sleeve 6, and the hopper 10 is a bellows. The second baffle 11 is installed on the other side of the hopper 10. Compressing the distance between the first baffle 8 and the second baffle 11 can compress the internal space of the hopper 10. The application port 14 is located on the side of the second baffle 11 away from the hopper 10 and is used to apply hydrogel to the affected area. The two ends of the slide rod 12 slide through the first baffle 8 and the second baffle 11 respectively, and nuts for limiting the position are installed at both ends of the slide rod 12. There are two slide rods 12, which are symmetrically arranged with respect to the hopper 10. The spring 13 is sleeved on the slide rod 12 and is located between the first baffle 8 and the second baffle 11. The first through groove 15 and the second through groove 16 are respectively opened on the second baffle 11 and the first baffle 8, and they correspond to each other. One end of the limiting strip 17 is rotatably installed in the first through groove 15, and the other end passes through the second through groove 16. The limiting strip 17 is inclined outward from the first through groove 15 towards the second through groove 16. There are several locking teeth 18, which are equally spaced and installed on the side of the limiting strip 17 away from the hopper 10. The retaining tooth 18 is a right-angled triangle, with one side perpendicular to the limiting strip 17 forming a straight surface 19, and the other side inclined relative to the limiting strip 17 forming a bevel 20. The edge of the second through groove 16 forms a retaining surface 21, and the straight surface 19 engages with the retaining surface 21. The leaf spring 22 is installed in the second through groove 16. The limiting buckle 23 is installed on the outer wall of the sleeve 6, and the leaf spring 22 is located inside the limiting buckle 23. The limiting buckle 23 ensures that the leaf spring 22 can stably undergo relative displacement when deformed, preventing it from detaching.

[0027] In use, the above structure involves connecting the sleeve 6 to the conveying cylinder 1, inserting the slider 7 into the slot 5, and simultaneously connecting the outlet 4 to the insertion port 9. The hydrogel is then pushed into the hopper 10 via the mixing and conveying mechanism. Subsequently, the second baffle 11 is pushed towards the first baffle 8 to expel excess gas from the hopper 10. After the gas is expelled, the hydrogel can be squeezed out through the application port 14 and applied to the affected area. During this process, whenever the second baffle 11 is pushed, the inclined surface 20 is limited by the locking surface 21, causing the limiting strip 17 to swing. This simultaneously drives the leaf spring 22 to undergo elastic deformation, and the spring 13 is compressed. When the locking tooth 18 passes the second through slot 16, the elastic force of the leaf spring 22 drives the limiting strip 17 to swing in the opposite direction, causing the straight surface 19 to engage with the locking surface 21. At this time, the elastic force of the spring 13 ensures that the second baffle 11 tends to move away from the first baffle 8, thereby ensuring a stable engagement between the straight surface 19 and the locking surface 21, thus guaranteeing structural stability. In this design, the setting of several locking teeth 18 ensures that the second baffle 11 can be effectively braked every time it moves a small distance, thereby ensuring that the same amount of hydrogel is squeezed out each time. This helps to provide intermittent hydrogel output to different affected areas and ensures that no hydrogel is output when the second baffle 11 is not squeezed.

[0028] refer to Figure 1 , Figure 2 , Figure 3 , Figure 5 , Figure 7 and Figure 10The feeding mechanism includes: a connecting frame 24, a feeding pipe 25, a material cylinder 26, a cylinder cover 27, a first gear 28, a second gear 29, a second motor 30, a lead screw 31, a limiting groove 32, a push plate 33, a connecting plate 34, and a top plate 35. The connecting frame 24 is installed at the end of the conveying cylinder 1 furthest from the coating mechanism. There are two feeding pipes 25, one end connected to the connecting frame 24 and the other end connected to the conveying cylinder 1. There are two cylinder covers 27, each rotatably connected to the lower surface of the top plate 35. There are two material cylinders 26, the bottom end of which is placed on the top of the connecting frame 24 and extends into the two feeding pipes 25. The bottom end of the material cylinder 26 has an outlet for the hydrogel raw material. The two cylinder covers 27 are screwed to the top ends of the two material cylinders 26 respectively. There are two first gears 28, each rotatably mounted on the upper surface of the top plate 35, and the two first gears 28 mesh with each other. The second gear 29 is rotatably mounted on the upper surface of the top plate 35 and meshes with one of the first gears 28. When the second gear 29 rotates, it drives the meshing first gear 28 to rotate, thereby causing the two first gears 28 to rotate synchronously in opposite directions. The second motor 30 is mounted on the lower surface of the top plate 35, and the output end of the second motor 30 is connected to the second gear 29. There are two lead screws 31, which are screwed to the two first gears 28 respectively. The bottom end of the lead screw 31 extends into the feed cylinder 26. A limiting groove 32 is axially formed on the lead screw 31. The top plate 35 is provided with a protrusion that matches the limiting groove 32, and the protrusion is installed in the limiting groove 32. By using the protrusion to limit the limiting groove 32, it can be ensured that the lead screw 31 only moves in the axial direction and avoids rotation. The threads of the two lead screws 31 are connected, thus ensuring that when the two first gears 28 rotate in opposite directions, they can drive the two lead screws 31 to move synchronously upward or downward. A pusher plate 33 is mounted at the bottom end of the lead screw 31, and its surface is provided with a rubber pad for pushing the hydrogel material in the barrel 26. It also includes a sealing component, comprising: a rotating shaft 36, a cover plate 37, a torsion spring 38, and a mounting block 39. The mounting block 39 is mounted at the bottom end of the barrel 26, and the rotating shaft 36 is rotatably connected to the mounting block 39. The cover plate 37 is mounted on the rotating shaft 36 and is used to block the hydrogel material outlet at the bottom end of the barrel 26. The torsion spring 38 is installed between the cover plate 37 and the mounting block 39. It is worth noting that in this embodiment, the method of starting the rotation of the second gear 29 is not limited to using the second motor 30; the bottom end of the rotating shaft of the second gear 29 passes through the top plate 35 and is configured in a spline form. In use, the rotation of the second gear 29 can be achieved by rotating this spline, thus enabling manual rotation of the second gear 29 without using the second motor 30 as a driving force.

[0029] In actual use, the material for the hydrogel is pre-filled into the material cylinder 26. Then, the pusher plate 33 is aligned with the material cylinder 26, and the cylinder cover 27 is screwed on. The two material cylinders 26 are selected according to different sizes, and a suitable pusher plate 33 is selected based on the model, so that the pusher plate 33 can push out the corresponding amount of hydrogel material after moving. In this embodiment, the two material cylinders 26 are respectively filled with oxidized hyaluronic acid (OHA) substrate and glucose oxidase (GOx+) hydrogen peroxide (H2O2) initiator, but it is not limited to these types; the selection can be made according to actual needs. Then, the second motor 30 is turned on, driving the second gear 29 and the first gear 28 to rotate. At this time, the lead screw 31 moves downward, thereby using the pusher plate 33 to push the hydrogel material. The material pushes open the cover plate 37, allowing the material to enter the mixing and conveying mechanism.

[0030] The specific embodiments described above do not constitute a limitation on the scope of protection of this invention. Those skilled in the art should understand that various modifications, combinations, sub-combinations, and substitutions can be made according to design requirements and other factors. Any modifications, equivalent substitutions, and improvements made within the spirit and principles of this invention should be included within the scope of protection of this invention.

Claims

1. A two-component, ready-to-mix and injectable preparation device for diabetic foot repair using hydrogel, characterized in that, include: A mixing and conveying mechanism and a pressure coating mechanism; the pressure coating mechanism is installed at one end of the mixing and conveying mechanism, which can convey the two gel components to the pressure coating mechanism and mix them at the same time. The pressure coating mechanism is controlled and can shrink the inner cavity volume to extrude the internal gel. The mixing mechanism includes: a conveying cylinder (1), a first motor (2), an auger (3), and an outlet (4); The first motor (2) is installed at the end of the conveying cylinder (1); the auger (3) is rotatably installed inside the conveying cylinder (1), and one end of it is connected to the output end of the first motor (2); the outlet (4) is installed at the end of the conveying cylinder (1) away from the first motor (2); The pressure coating mechanism includes: a first baffle (8), an inlet (9), a material hopper (10), a second baffle (11), a coating inlet (14), a first through groove (15), a second through groove (16), a limiting strip (17), and a locking tooth (18). The insertion port (9) is opened on the first baffle (8); the outlet (4) is inserted into the insertion port (9); one side of the hopper (10) is installed on one side of the first baffle (8); the second baffle (11) is installed on the other side of the hopper (10); the application port (14) is located on the side of the second baffle (11) away from the hopper (10); the first through groove (15) and the second through groove (16) are respectively opened on the second baffle (11) and the first baffle (8), and they correspond to each other; one end of the limiting strip (17) is rotatably installed in the first through groove (15), and the other end passes through the second through groove (16); there are several locking teeth (18), which are equidistantly installed on the side of the limiting strip (17) away from the hopper (10); the locking teeth (18) are engaged with the second through groove (16).

2. The two-component, ready-to-mix and injectable hydrogel preparation device for diabetic foot repair according to claim 1, characterized in that, The pressure coating mechanism further includes: a slide bar (12) and a spring (13); The two ends of the slide rod (12) slide through the first baffle (8) and the second baffle (11) respectively. There are two slide rods (12), which are symmetrically arranged relative to the hopper (10). The spring (13) is sleeved on the slide rod (12) and is located between the first baffle (8) and the second baffle (11).

3. The two-component, ready-to-mix and injectable hydrogel preparation device for diabetic foot repair according to claim 2, characterized in that, The pressure coating mechanism further includes: a slot (5), a sleeve (6), and a slider (7); The slot (5) is formed on the outer wall of one end of the conveying cylinder (1), and the slot (5) is an L-shaped device; the sleeve (6) is slidably installed on the end of the conveying cylinder (1); the slider (7) is installed on the inner wall of the sleeve (6), and the slider (7) is slidably installed in the slot (5); the first baffle (8) is rotatably installed on the sleeve (6).

4. The two-component, ready-to-mix and injectable hydrogel preparation device for diabetic foot repair according to claim 3, characterized in that, The coating mechanism further includes: a straight surface (19), an inclined surface (20), and a card surface (21); The locking teeth (18) are set in right-angled triangles, with one side perpendicular to the limiting strip (17) forming a straight surface (19) and the other side inclined relative to the limiting strip (17) forming a slope (20). The edge of the second through groove (16) forms a locking surface (21), and the straight surface (19) engages with the locking surface (21).

5. The two-component, ready-to-mix and injectable hydrogel preparation device for diabetic foot repair according to claim 4, characterized in that, The coating mechanism also includes: leaf spring (22) and limit buckle (23); The leaf spring (22) is installed in the second through groove (16); the limiting buckle (23) is installed on the outer wall of the sleeve (6), and the leaf spring (22) is located inside the limiting buckle (23).

6. The two-component, ready-to-mix and injectable hydrogel preparation device for diabetic foot repair according to claim 5, characterized in that, The limiting strip (17) is inclined outward from the first through groove (15) towards the second through groove (16).

7. The two-component, ready-to-mix and injectable hydrogel preparation device for diabetic foot repair according to claim 6, characterized in that, The outlet (4) is equipped with a one-way valve, and the discharge direction of the one-way valve is towards the side away from the conveying cylinder (1).

8. The two-component, ready-to-mix and injectable hydrogel preparation device for diabetic foot repair according to claim 1, characterized in that, Also includes: Feeding mechanism; The feeding mechanism is installed at the end of the mixing and conveying mechanism away from the coating mechanism, and is used to push the gel two-component raw material into the mixing and conveying mechanism.

9. The two-component, ready-to-mix and injectable preparation device for diabetic foot repair using hydrogel according to any one of claims 1-8, characterized in that, The feeding mechanism includes: a connecting frame (24), a feeding pipe (25), a material cylinder (26), a cylinder cover (27), a first gear (28), a second gear (29), a second motor (30), a lead screw (31), a limiting groove (32), a push plate (33), a connecting plate (34), and a top plate (35); The connecting frame (24) is installed at the end of the conveying cylinder (1) away from the coating mechanism; there are two discharge pipes (25), one end of which is connected to the connecting frame (24) and the other end of which is connected to the conveying cylinder (1); there are two cylinder covers (27), which are rotatably connected to the lower surface of the top plate (35); there are two material cylinders (26), the bottom end of which is placed on the top of the connecting frame (24) and extends into the two discharge pipes (25); the two cylinder covers (27) are screwed to the top of the two material cylinders (26); there are two first gears (28), which are rotatably installed on the upper surface of the top plate (35) and the two first gears (28) mesh with each other; The second gear (29) is rotatably mounted on the upper surface of the top plate (35) and meshes with one of the first gears (28); the second motor (30) is mounted on the lower surface of the top plate (35) and the output end of the second motor (30) is connected to the second gear (29); there are two lead screws (31), which are screwed to the two first gears (28) respectively, and the bottom end of the lead screw (31) extends into the material cylinder (26); the limiting groove (32) is axially opened on the lead screw (31); the top plate (35) is provided with a protrusion that matches the limiting groove (32) and the protrusion is installed in the limiting groove (32); the push plate (33) is installed at the bottom end of the lead screw (31).

10. The two-component, ready-to-mix and injectable hydrogel preparation device for diabetic foot repair according to claim 9, characterized in that, The feeding mechanism also includes a blocking component; the blocking component includes: a rotating shaft (36), a cover plate (37), a torsion spring (38), and a mounting block (39). The mounting block (39) is installed at the bottom of the material cylinder (26), and the rotating shaft (36) is rotatably connected to the mounting block (39); the cover plate (37) is installed on the rotating shaft (36); and the torsion spring (38) is installed between the cover plate (37) and the mounting block (39).

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