Apparatus for small-area cooling of human body surface, refrigerant composition and refrigeration method

Abstract

This invention relates to a small-area cooling device, cooling composition, and cooling method for the human body. It includes a flexible substrate that conforms to human skin, an independently sealed water storage unit, a solid heat-absorbing unit, a dedicated triggering structure, and a flow-guiding structure. The solid heat-absorbing unit contains a solid cooling composition and is isolated from the water storage unit. The dedicated triggering structure is simply a press-to-pierce or easy-tear-off sealing film structure. The flow-guiding structure is located between the water storage unit and the solid heat-absorbing unit. The solid heat-absorbing agent is selected from a specific combination of substances. The cooling method achieves solid-liquid mixing by breaking the sealing film through the dedicated triggering structure, and the liquid is evenly diffused through the flow-guiding structure, achieving cooling through an endothermic reaction. This invention can accurately achieve instantaneous cooling of a small area on the human body surface. It is convenient to trigger, safe and comfortable to use, simple and portable in structure, and adaptable to various forms such as patches and adhesive bandages. It can be widely used in local cold compress care scenarios.

Description

Technical Field

[0001] This invention relates to the field of physical cold compresses on the human body surface, specifically to a cooling device, cooling composition, and cooling method for small areas of the human body surface. Background Technology

[0002] Natural ice is often used to cool the body surface, but its temperature is uncontrollable, it can easily cause frostbite, it cannot maintain a reasonable temperature range for cold compresses, and it is inconvenient to carry and is prone to melting and leakage.

[0003] Existing cold compress products mostly use rubbing, squeezing, electromagnetic induction and other triggering methods, which generally have problems such as uneven cooling, large temperature fluctuations and inability to maintain the target temperature zone stably in a short period of time.

[0004] Therefore, it is essential to provide a cooling device, cooling composition, and cooling method for small areas of the human body surface to solve the above-mentioned technical problems. Summary of the Invention

[0005] Based on the above description, the present invention provides a cooling device, a cooling composition, and a cooling method for small areas of the human body surface, in order to solve the problems of uneven cooling, large temperature fluctuations, and inability to stably maintain the target temperature range in a short period of time that are common in the prior art.

[0006] The technical solution of this invention to solve the above-mentioned technical problems is as follows: A small-area cooling device for the human body surface, comprising a flexible substrate that conforms to human skin, an independently sealed water storage unit, a solid heat absorption unit, a dedicated triggering structure, and a flow guiding structure, wherein the effective cooling area of ​​the flexible substrate that conforms to human skin is ≤5cm². 2 The independently sealed water storage unit releases 30μL to 150μL of water per trigger, and the water storage unit is equipped with a sealing isolation membrane; the solid heat-absorbing unit has a built-in solid refrigeration composition and is isolated from the water storage unit by the sealing isolation membrane; the dedicated triggering structure is only a press-to-puncture structure or an easy-tear-off sealing membrane structure, excluding rubbing, squeezing, electromagnetic, heating and all other triggering methods; the flow guiding structure is located between the independently sealed water storage unit and the solid heat-absorbing unit.

[0007] Furthermore, solid-liquid mixing cooling is achieved solely by breaking the sealing membrane through the exclusive trigger structure. After triggering, the body surface temperature is below 0°C within 0 to 30 seconds and stabilizes at -10°C to 15°C within 1 to 10 minutes.

[0008] Furthermore, the flow guiding structure is provided with one or more combinations of 1 to 20 microchannels, porous flow guiding membrane, capillary core, and absorbent nonwoven fabric.

[0009] Furthermore, the diameter of the microchannel is 0.1 mm to 1.0 mm.

[0010] Furthermore, the patch, dressing, cold compress, adhesive bandage, or portable cooling patch is composed of the flexible substrate that conforms to human skin, an independently sealed water storage unit, a solid heat absorption unit, a dedicated triggering structure, and a flow guiding structure.

[0011] On one hand, a refrigeration composition for instantaneous cooling of a small area on the human body surface is provided. The refrigeration composition is a solid-liquid separation system, wherein the dosage of the solid endothermic unit is 60mg–200mg, and the corresponding water volume is 30μL–150μL, with a dosage error... ; Solid endothermic agents are selected from one or more of the following: Combinations of ammonium salts and organic carboxylic acids; Urea, potassium chloride, magnesium chloride, potassium acetate, thiourea, guanidine nitrate, guanidine carbonate; Xylitol, erythritol, and sorbitol. Further, the dosage of the solid endothermic unit... Susceptible to frostbite, the dosage of the solid heat-absorbing unit is reduced. It cannot achieve instantaneous cooling below 0°C or exceeding 15°C within 10 minutes.

[0012] Furthermore, the refrigeration composition is selected from at least one of chemical reaction endothermic systems, physical dissolution endothermic systems, and solid-liquid phase change endothermic systems.

[0013] On the other hand, a cooling method for instantaneous cooling of a small area on the human body surface is provided, characterized by comprising: ≤5cm on the human body surface 2 The area uses a solid-liquid separation refrigeration composition, with a sealed isolation membrane between the solid and liquid components; Mixing is triggered solely by pressing to puncture the sealing film or by easily peeling off the sealing film; no other triggering methods are used. Uniform liquid diffusion is achieved through 1 to 20 microchannels or equivalent flow guiding structures; Refrigeration is achieved through heat absorption via chemical reaction or physical dissolution. To lower the body surface temperature below 0°C within 0 to 30 seconds, and stabilize it at -10°C to 15°C within 1 to 10 minutes; If the solid dosage deviates from ±10%, the above temperature effect cannot be achieved.

[0014] Compared with the prior art, the technical solution of this application has the following beneficial technical effects: 1. It is suitable for cooling needs of small areas on the human body surface. The flexible material can closely fit the skin to improve the comfort of use. At the same time, it can accurately control the cooling range to avoid unnecessary stimulation or damage to the skin caused by large-area cooling. It is suitable for local cold compresses, instant cooling care and other scenarios. 2. The independent sealing design prevents water leakage and ensures the stability of the device during storage and transportation; the precise control of water release ensures that the water reacts fully with the solid heat absorption unit to achieve a rapid cooling effect, while avoiding excessive or insufficient water that could lead to poor cooling or waste; the sealing membrane effectively separates the solid and liquid, ensuring that the device is in a stable state when not triggered, thus extending its storage life. 3. Solid-state refrigeration compositions are stable to store and easy to carry. The isolation design prevents premature contact between solid and liquid before use, ensuring that an endothermic reaction can occur quickly after triggering, providing stable power for instantaneous cooling. Furthermore, the solid form makes it easier to control the dosage, ensuring consistent cooling effect. 4. The triggering method is simple and convenient, requiring no additional tools, and can quickly trigger cooling; 5. It can guide the liquid released from the water storage unit to diffuse evenly and quickly to the solid heat absorption unit, so that the solid and liquid can fully contact and react evenly, avoiding uneven cooling and poor instantaneous cooling effect caused by insufficient local reaction. At the same time, it can accelerate the cooling reaction speed and help achieve the core requirement of "instant cooling". Attached Figure Description

[0015] Figure 1 A schematic diagram of a small-area cooling device for the human body surface provided in an embodiment of the present invention. Figure 1 ; Figure 2 A schematic diagram of a small-area cooling device for the human body surface provided in an embodiment of the present invention. Figure 2 .

[0016] The attached diagram lists the components represented by each number as follows: 1. Flexible substrate that conforms to human skin; 2. Independently sealed water storage unit; 3. Solid heat absorption unit; 4. Dedicated triggering structure; 5. Flow guiding structure; 6. Sealing isolation membrane. Detailed Implementation

[0017] To facilitate understanding of this application, a more complete description will be provided below with reference to the accompanying drawings, which illustrate embodiments of the present application. However, the present application can be implemented in many different forms and is not limited to the embodiments described herein. Rather, these embodiments are provided so that the disclosure of this application will be thorough and complete.

[0018] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the application.

[0019] It is understood that spatial relation terms such as "below," "under," "below," "below," "above," "over," etc., can be used here to describe the relationship between one element or feature shown in the figure and other elements or features. It should be understood that, in addition to the orientation shown in the figure, spatial relation terms also include different orientations of the device in use and operation. For example, if the device in the figure is flipped, the element or feature described as "below" or "under" or "below" of the other element or feature will be oriented "over" the other element or feature. Therefore, the exemplary terms "below" and "under" can include both upper and lower orientations. Furthermore, the device may also include other orientations, such as being rotated 90 degrees or other orientations, and the spatial descriptive terms used herein will be interpreted accordingly.

[0020] It should be noted that when one element is considered to be "connected" to another element, it can be directly connected to the other element or connected to the other element through an intermediary element. In the following embodiments, "connection" should be understood as "electrical connection," "communication connection," etc., if the connected circuits, modules, units, etc., have the transmission of electrical signals or data between them.

[0021] When used herein, the singular forms of “a,” “an,” and “the” may also include the plural forms unless the context clearly indicates otherwise. It should also be understood that the terms “comprising,” “including,” or “having,” etc., specify the presence of the stated feature, whole, step, operation, component, part, or combination thereof, but do not preclude the possibility of the presence or addition of one or more other features, wholes, steps, operations, components, parts, or combinations thereof.

[0022] like Figures 1 to 2 As shown, a small-area cooling device for the human body surface includes a flexible substrate 1 that conforms to human skin, an independently sealed water storage unit 2, a solid heat absorption unit 3, a dedicated triggering structure 4, and a flow guiding structure 5. The effective cooling area of ​​the flexible substrate 1 conforming to human skin is ≤5cm². 2 The independently sealed water storage unit 2 releases water in a single triggering action of 30μL to 150μL, and the water storage unit is equipped with a sealing isolation membrane 6; the solid heat absorption unit 3 has a built-in solid refrigeration composition and is isolated from the water storage unit by the sealing isolation membrane 6; the dedicated triggering structure 4 is only a press-to-puncture structure or an easy-tear-off sealing membrane structure, excluding rubbing, squeezing, electromagnetic, heating and all other triggering methods; the flow guiding structure 5 is located between the independently sealed water storage unit 2 and the solid heat absorption unit 3.

[0023] In some embodiments, solid-liquid mixing cooling is achieved by breaking the sealing membrane only through the dedicated trigger structure 4. After triggering, the body surface temperature is below 0°C within 0 to 30 seconds and stabilizes at -10°C to 15°C within 1 to 10 minutes.

[0024] In some embodiments, the flow guiding structure 5 is provided with one or more combinations of 1 to 20 microchannels, porous flow guiding membrane, capillary core, and absorbent nonwoven fabric.

[0025] In some embodiments, the diameter of the microchannel is 0.1 mm to 1.0 mm.

[0026] In some embodiments, the flexible substrate 1 that conforms to human skin, the independently sealed water storage unit 2, the solid heat absorption unit 3, the dedicated triggering structure 4, and the flow guiding structure 5 constitute a patch, dressing, cold compress, adhesive bandage, or portable cooling patch.

[0027] On one hand, a refrigeration composition for instantaneous cooling of a small area on the human body surface is provided. The refrigeration composition is a solid-liquid separation system, wherein the dosage of the solid heat-absorbing unit 3 is 60mg–200mg, and the corresponding water volume is 30μL–150μL, with a dosage error... ; Solid endothermic agents are selected from one or more of the following: Combinations of monoammonium salts with organic carboxylic acids; 2. Urea, potassium chloride, magnesium chloride, potassium acetate, thiourea, guanidine nitrate, guanidine carbonate; 3. Xylitol, erythritol, sorbitol.

[0028] In some embodiments, the dose of the solid heat-absorbing unit 3 Susceptible to frostbite, the dose of the solid heat-absorbing unit 3 is reduced. It cannot achieve instantaneous cooling below 0°C or exceeding 15°C within 10 minutes.

[0029] In some embodiments, the refrigeration composition is selected from at least one of chemical reaction endothermic systems, physical dissolution endothermic systems, and solid-liquid phase change endothermic systems.

[0030] On the other hand, a cooling method for instantaneous cooling of a small area on the human body surface is provided, characterized by comprising: ≤5cm on the human body surface 2 The region uses a solid-liquid separation refrigeration composition, with a sealed isolation membrane 6 between the solid and liquid components; Mixing is triggered solely by pressing to puncture the sealing film or by easily peeling off the sealing film; no other triggering methods are used. Uniform liquid diffusion is achieved through 1 to 20 microchannels or equivalent flow guiding structures; Refrigeration is achieved through heat absorption via chemical reaction or physical dissolution. To lower the body surface temperature below 0°C within 0 to 30 seconds, and stabilize it at -10°C to 15°C within 1 to 10 minutes; If the solid dosage deviates from ±10%, the above temperature effect cannot be achieved.

[0031] Example 2: Cooling area 2.5cm 2 The solid composition is a mixture of ammonium bicarbonate and citric acid monohydrate (80 mg) and citric acid monohydrate (50 μL). It uses 5 microchannels and is triggered by a press-and-puncture method. After triggering, the temperature drops to -3°C in 20 seconds and is maintained at -3°C to 12°C for 1 to 10 minutes.

[0032] Example 3: Cooling area 3cm 2 The solid is 100mg of urea and 60μL of water. It is guided by non-woven fabric and triggered by easy-tear peeling. After triggering, the temperature drops to -1℃ in 30 seconds and is maintained at -1℃ to 14℃ for 1 to 10 minutes.

[0033] Example 4: Cooling area 2cm 2 The solid is 120 mg xylitol, the water volume is 70 μL, and there are 10 microchannels. It is triggered by pressing. After triggering, the temperature drops to -2℃ in 25 seconds and is maintained at -2℃ to 13℃ for 1 to 10 minutes.

[0034] Example 5: The solid is a mixture of urea, ammonium bicarbonate and citric acid monohydrate (90 mg), with a water volume of 55 μL. It uses a porous membrane for flow and is easy to trigger. After triggering, the temperature drops to -4°C in 20 seconds and is maintained at -4°C to 11°C for 1 to 10 minutes.

[0035] Example 6: Example of a urea + ammonium chloride compound refrigeration composition (optimal example): This embodiment provides a refrigeration composition for instantaneous cooling of a small area on the human body surface. The refrigeration composition, by mass percentage, consists of a mixture of 60% urea and 40% ammonium chloride. The corresponding refrigeration device adopts the 5×5cm sealed flexible soft-pack structure described in this invention. The device's interior is divided by a sealed isolation membrane 6 into an independently sealed water storage unit 2 and a solid heat-absorbing unit 3. The solid heat-absorbing unit 3 is filled with the urea-ammonium chloride composite refrigeration composition described in this embodiment, and the independently sealed water storage unit 2 is encapsulated with purified water.

[0036] The cooling method corresponding to this embodiment is as follows: During use, pressing the pinch-to-break trigger structure 4 punctures the sealing membrane 6 between the two cavities. The pure water inside the water storage unit 2 diffuses evenly to the solid heat-absorbing unit 3 via the flow guiding structure 5, fully contacting the internal urea and ammonium chloride mixed powder, resulting in a dissolution and endothermic reaction. At an ambient temperature of 25℃, the temperature of the cooling zone can drop to -8℃ to -12℃ within one minute after material mixing, and subsequently maintain a stable low temperature around -10℃ for 10 to 12 minutes. The stable cooling time is close to that of traditional ammonium nitrate cold packs. All raw materials used in this embodiment are non-regulated chemical raw materials. The overall composition is non-toxic and non-irritating, the raw materials are readily available, the production cost is low, and no toxic or harmful substances are released throughout the process, making it perfectly suited for the needs of small-area cold compresses and instantaneous cooling on the human body.

[0037] Example 7: Example of a urea + potassium nitrate compound refrigeration composition (secondary example): This embodiment provides a refrigeration composition for instantaneous cooling of a small area on the human body surface. The refrigeration composition, by mass percentage, consists of a mixture of 70% urea and 30% potassium nitrate. The corresponding refrigeration device uses the 5×5cm sealed flexible soft-pack structure described in this invention. The device's interior is divided by a sealed isolation membrane 6 into an independently sealed water storage unit 2 and a solid heat-absorbing unit 3. The solid heat-absorbing unit 3 is filled with the urea-potassium nitrate composite refrigeration composition described in this embodiment, while the independently sealed water storage unit 2 is encapsulated with purified water.

[0038] The refrigeration method in this embodiment is as follows: During use, pressing the pinch-to-break trigger structure 4 punctures the sealing isolation membrane 6, allowing the pure water in the water storage unit to come into contact with and mix with the composite powder in the solid heat-absorbing unit, resulting in a dissolution and endothermic reaction. At an ambient temperature of 25°C, the temperature of the refrigeration area after the mixing reaction can drop to -7°C to -10°C, and the low-temperature stability is maintained for 10 minutes. The material dissolution process in this embodiment is gentle and gradual, with small temperature fluctuations throughout the refrigeration process and excellent temperature control stability. It is suitable for small-area refrigeration scenarios requiring stable low temperatures and high-precision temperature control on the human body surface. All raw materials used are non-regulated, non-toxic, and readily available.

[0039] Example 8: Example of a single-component refrigeration composition using pure urea (simplest structural example) This embodiment provides a refrigeration composition for instantaneous cooling of a small area on the human body surface. The refrigeration composition is a single-component material of pure urea, without any additional compounding additives. The corresponding refrigeration device adopts the 5×5cm sealed flexible soft package structure described in this invention. The device is internally divided into an independently sealed water storage unit 2 and a solid heat absorption unit 3 by a sealing isolation membrane 6. The solid heat absorption unit 3 is filled with pure urea powder, and the independently sealed water storage unit 2 is encapsulated with pure water.

[0040] The refrigeration method in this embodiment is as follows: During use, pressing the pinch-to-break trigger structure 4 punctures the sealing membrane 6, allowing pure water to come into contact with the urea powder and undergo a dissolution and endothermic reaction. At an ambient temperature of 25°C, the temperature of the refrigeration zone after material mixing can drop to -5°C to -8°C, and the low-temperature stability is maintained for 8 to 10 minutes. This embodiment features the simplest formula structure, a single component, and uses completely non-regulated, non-toxic materials as raw materials. The processing and preparation process is extremely simple, resulting in the lowest cost. It is suitable for basic refrigeration scenarios involving small areas of the human body with mild low-temperature requirements and simple operation.

[0041] Compared with the prior art, the technical solution of this application has the following beneficial technical effects: 1. It is suitable for cooling needs of small areas on the human body surface. The flexible material can closely fit the skin to improve the comfort of use. At the same time, it can accurately control the cooling range to avoid unnecessary stimulation or damage to the skin caused by large-area cooling. It is suitable for local cold compresses, instant cooling care and other scenarios. 2. The independent sealing design prevents water leakage and ensures the stability of the device during storage and transportation; the precise control of water release ensures that the water reacts fully with the solid heat absorption unit to achieve a rapid cooling effect, while avoiding excessive or insufficient water that could lead to poor cooling or waste; the sealing membrane effectively separates the solid and liquid, ensuring that the device is in a stable state when not triggered, thus extending its storage life. 3. Solid-state refrigeration compositions are stable to store and easy to carry. The isolation design prevents premature contact between solid and liquid before use, ensuring that an endothermic reaction can occur quickly after triggering, providing stable power for instantaneous cooling. Furthermore, the solid form makes it easier to control the dosage, ensuring consistent cooling effect. 4. The triggering method is simple and convenient, requiring no additional tools, and can quickly trigger cooling; 5. It can guide the liquid released from the water storage unit to diffuse evenly and quickly to the solid heat absorption unit, so that the solid and liquid can fully contact and react evenly, avoiding uneven cooling and poor instantaneous cooling effect caused by insufficient local reaction. At the same time, it can accelerate the cooling reaction speed and help achieve the core requirement of "instant cooling".

[0042] The present invention and its embodiments have been described above. This description is not restrictive, and the accompanying drawings are only one embodiment of the present invention; the actual structure is not limited thereto. In conclusion, if those skilled in the art are inspired by this description and design similar structures and embodiments without departing from the spirit of the invention, such designs should fall within the protection scope of the present invention.

Claims

1. A cooling device for a small area of ​​the human body surface, characterized in that, include: Flexible substrate (1) that conforms to human skin, with an effective cooling area ≤ 5cm² 2 ; The independent sealed water storage unit (2) has a single trigger release volume of 30μL to 150μL and the water storage unit is equipped with a sealed isolation membrane. The solid heat absorption unit (3) has a built-in solid refrigeration composition and is isolated from the water storage unit by a sealed isolation membrane (6); The exclusive triggering structure (4) is only a press-to-puncture structure or an easy-tear-off sealing film structure, excluding rubbing, squeezing, electromagnetic, heating and all other triggering methods; A flow guiding structure (5) is provided between the independently sealed water storage unit (2) and the solid heat absorption unit (3).

2. The cooling device for a small area of ​​the human body surface according to claim 1, characterized in that, Solid-liquid mixing refrigeration is achieved by breaking the sealing film through the exclusive trigger structure (4). After triggering, the body surface temperature is below 0°C within 0 to 30 seconds and stabilizes at -10°C to 15°C within 1 to 10 minutes.

3. The cooling device for a small area of ​​the human body surface according to claim 1, characterized in that, The flow guiding structure (5) is provided with 1 to 20 microchannels, porous flow guiding membrane, capillary core, absorbent nonwoven fabric or a combination thereof.

4. The cooling device for a small area of ​​the human body surface according to claim 3, characterized in that, The diameter of the microchannel is 0.1 mm to 1.0 mm.

5. The cooling device for a small area of ​​the human body surface according to claim 1, characterized in that, The patch, dressing, cold compress, bandage or portable cooling patch is composed of the flexible substrate (1) that fits the human skin, the independently sealed water storage unit (2), the solid heat absorption unit (3), the dedicated triggering structure (4) and the flow guiding structure (5).

6. A refrigeration composition for instantaneous cooling of a small area of ​​the human body surface, characterized in that, The refrigeration composition is a solid-liquid separation system. The dosage of the solid heat-absorbing unit (3) is 60mg to 200mg, and the corresponding water volume is 30μL to 150μL. The dosage error is... ; Solid endothermic agents are selected from one or more of the following: (1) Combinations of ammonium salts and organic carboxylic acids; (2) Urea, potassium chloride, magnesium chloride, potassium acetate, thiourea, guanidine nitrate, guanidine carbonate; (3) Xylitol, erythritol, sorbitol.

7. The refrigeration composition for instantaneous cooling of a small area of ​​the human body surface according to claim 6, characterized in that, The dose of the solid heat-absorbing unit (3) Susceptible to frostbite, the dose of the solid heat-absorbing unit (3) is reduced. It cannot achieve instantaneous cooling below 0°C or exceeding 15°C within 10 minutes.

8. The refrigeration composition for instantaneous cooling of a small area of ​​the human body surface according to claim 6, characterized in that, The refrigeration composition is selected from at least one of the following: chemical reaction endothermic system, physical dissolution endothermic system, and solid-liquid phase change endothermic system.

9. A refrigeration method for instantaneous cooling of a small area of ​​the human body surface, characterized in that, include: ≤5cm on the human body surface 2 The area uses a solid-liquid separation refrigeration composition with a sealed isolation membrane (6) between the solid and liquid; mixing is triggered only by pressing to puncture the sealing membrane or by easily tearing off the sealing membrane, without using any other triggering method; Uniform liquid diffusion is achieved through 1 to 20 microchannels or equivalent flow guiding structures; Refrigeration is achieved through heat absorption via chemical reaction or physical dissolution. To lower the body surface temperature below 0°C within 0 to 30 seconds, and stabilize it at -10°C to 15°C within 1 to 10 minutes; If the solid dosage deviates from ±10%, the above temperature effect cannot be achieved.

Images