A selective photodisruption system for the prevention and treatment of after cataract

The selective photoremoval system utilizes high-resolution imaging and adaptive energy-controlled laser technology to selectively remove lens epithelial cells and fibers, solving the problems of prevention and treatment of polymorphic keratitis (PCO) in existing technologies, reducing the incidence of PCO and avoiding structural damage and complications, thus providing non-invasive treatment.

CN122398534APending Publication Date: 2026-07-17THE EYE HOSPITAL OF WENZHOU MEDICAL UNIVERSITY +1

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
THE EYE HOSPITAL OF WENZHOU MEDICAL UNIVERSITY
Filing Date
2026-05-15
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing technologies for the prevention and treatment of secondary cataracts (PCO) suffer from poor preventive effects and excessively high treatment costs. In particular, Nd:YAG laser posterior capsulotomy carries unavoidable risks of structural damage and complications, while pharmacological interventions have risks of cytotoxicity and insufficient target specificity. Materials science improvements have not been able to effectively prevent the occurrence of PCO.

Method used

The selective photoremoval system includes a high-resolution imaging module, a pulsed laser source, and an adaptive energy control module. It identifies target tissue through high-resolution imaging, generates a three-dimensional laser scanning path, and uses pulsed laser to selectively remove lens epithelial cells and proliferating fibers, ensuring that the integrity of the posterior lens capsule structure is not damaged, while controlling the energy within the energy window.

Benefits of technology

It achieves selective removal of diseased tissue without damaging the lens capsule structure, fundamentally prevents PCO, reduces the incidence, avoids the risks of Nd:YAG laser, and provides truly non-invasive treatment results.

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Abstract

一种用于预防与治疗后发性白内障的选择性光清除系统,能够在不损伤晶状体囊膜结构的前提下,清除眼内的靶向病变组织,通过将脉冲激光的能量精确控制在高于病变组织清除阈值、但低于囊膜损伤阈值内,可实现对病变组织的选择性清除,同时确保囊膜结构完整无损,本发明可实现根源性预防及真正的无创治疗。在术中对LECs的彻底清除,从源头上极大降低PCO发生率。术后治疗模式通过清除纤维混浊层而非切开囊膜来恢复视力,革命性地保留了后囊膜的完整性,彻底规避了Nd:YAG激光的诸多风险。
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