Dopamine-modified alginate polysaccharide and polysaccharide derivatives, hydrogels prepared therefrom, and applications thereof
By dual modification of seaweed polysaccharides to form a synergistic dynamic network of borate ester bonds and metal-polyphenol coordination bonds, the shortcomings of existing hydrogels in terms of mechanical strength and intelligent responsiveness are solved, and a dopamine-modified seaweed polysaccharide hydrogel with high adhesion strength and intelligent responsiveness is prepared for application in the biomedical field.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- OCEAN UNIV OF CHINA
- Filing Date
- 2026-06-16
- Publication Date
- 2026-07-17
AI Technical Summary
Existing hydrogels struggle to achieve multifunctional integration in terms of excellent shear-thinning/self-healing rheological properties, intelligent responsiveness, and bioactivity. In particular, hydrogels based on dynamic covalent and non-covalent bonds are deficient in mechanical strength and tissue integration and repair capabilities.
By dual modification of seaweed polysaccharides, dopamine and phenylboronic acid groups are introduced to form a synergistic dynamic network of borate ester bonds and metal-polyphenol coordination bonds. Combined with a metal-polyphenol complexing crosslinking agent, a dual dynamic network is constructed to prepare dopamine-modified seaweed polysaccharide hydrogels.
The prepared hydrogel has good injectability, smart responsiveness and biocompatibility, and significantly improves adhesion strength and mechanical properties, making it suitable for medical adhesives, wound dressings and tissue engineering.
Smart Images
Figure CN122404592A_ABST