Infrared spectroscopy-based tumor organoid detection imaging analysis method

By integrating multi-dimensional feature data through infrared spectroscopy detection and imaging analysis, the problem of interference factors in existing technologies has been solved, enabling high-precision non-destructive detection and quantitative analysis of tumor organoids and providing a unified quantitative basis.

CN122409554APending Publication Date: 2026-07-17KIRIN (SHANDONG) PHARM TECH CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
KIRIN (SHANDONG) PHARM TECH CO LTD
Filing Date
2026-04-23
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing infrared spectroscopy detection technology is susceptible to interference from background scattering, instrument system errors, and macromolecular crowding effects in tumor organoid detection. It cannot achieve non-destructive, multi-dimensional visualization of molecular distribution, and lacks a unified quantitative analysis method, resulting in insufficient accuracy of detection results.

Method used

An infrared spectroscopy-based imaging and analysis method for tumor organoid detection is adopted. Through multimodal data acquisition, correction analysis, distribution analysis, and tumor assessment units, multidimensional feature data are integrated to output pixel-level molecular abundance, molecular spatial heterogeneity index, and comprehensive malignancy score, thereby achieving multidimensional imaging and detection analysis.

Benefits of technology

It achieves high-precision molecular distribution imaging, quantitatively reflects the clonal diversity and invasive potential of tumor organoids, provides a unified quantitative basis for benign and malignant grading and biological behavior determination, and avoids inconsistencies in manual interpretation.

✦ Generated by Eureka AI based on patent content.

Smart Images

  • Figure CN122409554A_ABST
    Figure CN122409554A_ABST
Patent Text Reader

Abstract

本发明公开了基于红外光谱的肿瘤类器官检测成像分析方法,本发明涉及检测成像分析技术领域,包括多模态数据采集模块、检测成像计算模块和检测成像分析模块,检测成像计算模块包括校正分析单元、分布情况单元和肿瘤评估单元,检测成像分析模块包括检测成像结果单元和检测分析结果单元。本发明的校正分析单元经多维度校正输出像素级分子定量数据,从源头保障定量与成像结果准确,分布情况单元输出分子空间异质性指数,填补现有红外类器官检测盲区,呈现侵袭潜能相关结构信息,肿瘤评估单元输出恶性程度综合评分,为良恶性判定、药物筛选及临床预后指导提供统一量化依据。
Need to check novelty before this filing date? Find Prior Art