Infrared spectroscopy-based tumor organoid detection imaging analysis method
By integrating multi-dimensional feature data through infrared spectroscopy detection and imaging analysis, the problem of interference factors in existing technologies has been solved, enabling high-precision non-destructive detection and quantitative analysis of tumor organoids and providing a unified quantitative basis.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- KIRIN (SHANDONG) PHARM TECH CO LTD
- Filing Date
- 2026-04-23
- Publication Date
- 2026-07-17
AI Technical Summary
Existing infrared spectroscopy detection technology is susceptible to interference from background scattering, instrument system errors, and macromolecular crowding effects in tumor organoid detection. It cannot achieve non-destructive, multi-dimensional visualization of molecular distribution, and lacks a unified quantitative analysis method, resulting in insufficient accuracy of detection results.
An infrared spectroscopy-based imaging and analysis method for tumor organoid detection is adopted. Through multimodal data acquisition, correction analysis, distribution analysis, and tumor assessment units, multidimensional feature data are integrated to output pixel-level molecular abundance, molecular spatial heterogeneity index, and comprehensive malignancy score, thereby achieving multidimensional imaging and detection analysis.
It achieves high-precision molecular distribution imaging, quantitatively reflects the clonal diversity and invasive potential of tumor organoids, provides a unified quantitative basis for benign and malignant grading and biological behavior determination, and avoids inconsistencies in manual interpretation.
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