Methods, systems, and kits for assessing microplastic kinetics during blood purification processes
By collecting and detecting the difference in microplastic concentration before and after blood samples, and combining a dynamic evaluation model and a decision information optimization module, this approach solves the problem of the inability to quantify the dynamic net effect of microplastics during blood purification treatment in existing technologies. It provides optimized treatment plans, reduces the risk of iatrogenic exposure, and improves clearance efficiency.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Applications(China)
- Current Assignee / Owner
- 南方医科大学第五附属医院
- Filing Date
- 2026-05-12
- Publication Date
- 2026-07-17
AI Technical Summary
Existing methods for detecting and assessing microplastics cannot quantify the dynamic net effect during blood purification treatment, cannot guide clinical operations, and have not established a quantitative relationship between key treatment parameters and microplastic dynamics, thus failing to reduce iatrogenic exposure and improve clearance efficiency.
By collecting blood samples from patients before and after treatment, the difference in microplastic concentration was detected using thermal pyrolysis gas chromatography-mass spectrometry. Combined with a dynamic evaluation model construction module, a key variable analysis module, and a decision information optimization module, the net effect of microplastics was quantified, and an optimized treatment plan was generated.
This study enables quantitative assessment of microplastic dynamics during blood purification, provides clinical operation guidance, reduces the risk of iatrogenic exposure, improves clearance efficiency, and expands the scope of medical device biocompatibility assessment to include the risk of microplastic release.
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Figure CN122409902A_ABST