Method for quantifying metabolic chamber animal behavior phenotypes

By using an RGB-D side-view acquisition system and deep learning algorithms, the problems of anti-interference and accuracy in the complex environment of the metabolic chamber were solved, and high-precision behavior quantification and automated analysis were achieved.

CN122415536APending Publication Date: 2026-07-17SHANGHAI UNIV OF MEDICINE & HEALTH SCI
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-04-23
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

In the complex environment of the metabolic chamber, existing technologies have weak anti-interference capabilities, limited spatial resolution, and insufficient accuracy in motion state measurement, leading to deviations in behavior quantification results.

Method used

An RGB-D side-view acquisition system is used, combined with deep learning algorithms, to segment animal target images through a multi-level filtering algorithm with depth threshold and region constraints. High-precision behavior recognition is achieved by automatically analyzing the key points of three-dimensional skeletons and posture features.

Benefits of technology

It achieves millimeter-level precision in physical space motion quantization, significantly improves anti-interference capabilities, accurately identifies fine behaviors in complex environments, and realizes full-process automation and high-precision analysis.

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Abstract

本发明涉及计算机视觉与图像处理技术领域,公开了一种代谢箱动物行为表型量化方法,包括:搭建侧视RGB‑D采集环境,划定笼体、跑轮、食槽及水瓶的感兴趣区域并构建静态背景模型;利用深度差分、最小面积阈值及ROI位置约束进行多级滤波,实时分割获取去背景的动物目标图像;将目标图像输入姿态估计网络提取解剖学骨骼关键点,并融合深度信息与针孔成像模型反投影重建关键点的三维物理空间坐标;构建时空特征序列,利用深度学习网络识别包括直立、进食、饮水等在内的精细行为;计算多维运动学参数与昼夜节律指标并生成可视化报表;本发明解决了现有技术中在代谢箱复杂实验环境下存在抗干扰能力弱、空间分辨率受限及运动状态测量精度不足的问题。
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