Method and system for brain tumor segmentation based on missing modality MRI using a full modality training framework reuse

By reusing the full-modal training framework, the model is divided into a Common model and a Barebone model. The representation and segmentation are optimized by aligning with the homologous mask, which solves the robustness and stability problem of MRI brain tumor segmentation under missing modalities and achieves high-efficiency segmentation performance under limited complete modal samples.

CN122415649APending Publication Date: 2026-07-17HANGZHOU DIANZI UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Filing Date
2026-05-14
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

Existing multimodal MRI brain tumor segmentation methods exhibit performance degradation under missing modal conditions, struggle to be trained collaboratively with a large number of missing modal samples under limited complete modal sample conditions, and suffer from inconsistencies between generated results and real data distribution.

Method used

A full-modal training framework reuse method is adopted, dividing the model into a Common model and a Barebone model. The Common model reuses the full modality learning capability during the training phase, while the Barebone model handles the missing modalities during the inference phase. Co-optimization of representation-level constraints and segmentation supervision is achieved through homogeneous mask alignment, thereby improving robustness and generalization ability.

Benefits of technology

This improved the clinical applicability and deployment stability of the missing modality MRI brain tumor segmentation model, reduced the distribution bias caused by pseudo-missing samples or pseudo-modal generation, and enhanced the model's stability and generalization ability under multiple combinations of real modal missingness.

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Abstract

基于全模态训练框架复用的缺失模态MRI脑肿瘤分割方法和系统,方法包括获取完整模态样本子集和缺失模态样本子集;对全模态分割框架进行模型分区,构建缺失模态脑肿瘤分割框架,其中,Common模型用于在训练阶段复用全模态训练框架中的完整模态学习能力;Barebone模型用于在推理阶段接收缺失模态样本并输出脑肿瘤分割结果;Barebone模型的参数集合包含于Common模型的参数集合;基于完整模态样本生成缺失模态组合子任务;利用缺失模态组合子任务对Common模型进行多缺失组合平衡预训练,生成平衡初始化参数;执行模型分区;基于同源掩码对齐执行Common模型与Barebone模型的协同训练。
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