Salt of reduced beta-nicotinamide mononucleotide and method of making same

By preparing reduced β-nicotinamide mononucleotides (β-nicotinamide mononucleotides) in the form of divalent metal salts (excluding calcium salts), potassium salts, and ammonium salts, the deliquescence problem of reduced β-nicotinamide mononucleotides has been solved, and the stability and flowability have been improved, making it suitable for various applications such as food and nutritional supplements.

CN122422334APending Publication Date: 2026-07-17KANEKA CORP
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
KANEKA CORP
Filing Date
2024-12-23
Publication Date
2026-07-17

AI Technical Summary

Technical Problem

The existing disodium salt of reduced β-nicotinamide mononucleotide has deliquescence problems during storage and distribution, making it difficult to manage stably.

Method used

Stable reduced β-nicotinamide mononucleotide salts were prepared by using divalent metal salts (excluding calcium salts), potassium salts, and ammonium salts, which were mixed with reduced β-nicotinamide mononucleotide in an aqueous solvent and extracted using anion exchange resin. Subsequently, the salts were reacted with an aqueous mixed organic solvent to precipitate and separate the salts.

Benefits of technology

The prepared salt is non-hygroscopic, which improves its storage stability and ease of distribution, making it suitable for a variety of uses.

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Abstract

本公开的目的在于，针对可期待优异的抗老化效果的还原型β‑烟酰胺单核苷酸(NMNH)，提供容易流通及处理的新型NMNH的盐、以及上述新型的NMNH的盐的制造方法。本实施方式之一是一种还原型β‑烟酰胺单核苷酸的盐，其为选自除钙盐以外的二价金属盐、钾盐及铵盐中的至少1种盐。
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