An anti-wrinkle repair composition based on elastin peptides, and a method for its preparation and use

Abstract

The present application relates to the technical field of health products, and discloses an anti-wrinkle repair composition based on elastin peptides, a preparation method and application thereof, the anti-wrinkle repair composition comprising the following components in parts by weight: 5-40 parts of elastin peptides, 5-30 parts of type I collagen peptides, 5-30 parts of type III collagen peptides, 1-5 parts of oat beta-glucan, 0.1-3 parts of hazel mushroom extract and 0.1-3 parts of bamboo yellow extract. The anti-wrinkle repair composition based on elastin peptides, the preparation method and the application thereof can inhibit the enzyme activity of MMP-1, reduce the destructive power of MMP-1 on collagen, thereby preventing the generation of wrinkles and achieving the purpose of anti-wrinkle and wrinkle removal.

Description

Technical Field

[0001] This invention relates to the field of health product technology, and in particular to an anti-wrinkle repair composition based on elastin peptides, its preparation method, and its application. Background Technology

[0002] As we age, the collagen in our skin gradually diminishes, and the reduction in subcutaneous fat leads to decreased skin elasticity, resulting in wrinkles and sagging. Furthermore, factors such as staying up late, irregular meals, or insufficient nutrition can also cause signs of aging in the skin. Additionally, sun exposure damages skin tissue, making the skin more prone to dryness and flaking, leading to discomfort. Researchers have investigated the causes of skin sagging, wrinkles, and damage, identifying the following main reasons: (1) age-related damage and loss of collagen and elastin; (2) slow collagen and elastin production; (3) photoaging caused by ultraviolet radiation, leading to increased metalloproteinases that damage collagen, or barrier damage and inflammation caused by ultraviolet radiation; and (4) expression lines caused by facial expressions. To slow the formation or worsening of wrinkles and to achieve firmer, smoother skin, consumers are increasingly demanding anti-wrinkle repair products.

[0003] Traditional anti-wrinkle repair products typically use active ingredients such as collagen, hyaluronic acid, and vitamin C to improve skin elasticity and firmness, reducing the appearance of wrinkles. However, single-component products have limited anti-wrinkle effects, while formulating multiple ingredients together can achieve multiple benefits. However, this approach relies heavily on the formulator's experience, has a low success rate, and the efficacy of combining multiple ingredients is often unclear. Therefore, improving anti-wrinkle repair effects remains a challenge.

[0004] Therefore, this invention proposes an anti-wrinkle repair composition based on elastin peptides and its preparation method. Summary of the Invention

[0005] The purpose of this invention is to provide an anti-wrinkle repair composition based on elastin peptides, its preparation method and application. The anti-wrinkle repair composition can inhibit MMP-1 enzyme activity and reduce the destructive power of MMP-1 enzyme on collagen, thereby preventing the formation of wrinkles and achieving the purpose of anti-wrinkle and wrinkle removal.

[0006] To achieve the above objectives, the present invention provides an anti-wrinkle repair composition based on elastin peptides, comprising the following components in parts by weight: 5-50 parts of elastin peptides, 10-40 parts of type I collagen peptides, 10-40 parts of type III collagen peptides, 1-5 parts of oat β-glucan, 0.1-3 parts of hazelnut mushroom extract, and 0.1-3 parts of bamboo extract.

[0007] Furthermore, an anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 40-50 parts of elastin peptides, 25-40 parts of type I collagen peptides, 20-40 parts of type III collagen peptides, 2-4 parts of oat β-glucan, 0.5-2 parts of hazelnut mushroom extract, and 0.5-2 parts of bamboo extract.

[0008] Furthermore, the molecular weight of the elastin peptide is less than 1000 Da, and the molecular weights of the type I collagen peptide and type III collagen peptide are less than 2000 Da.

[0009] Furthermore, the preparation method of hazel mushroom extract is as follows: The hazel mushrooms were washed, dried, and then pulverized to obtain hazel mushroom powder. The hazel mushroom powder was placed in a filter bag and extracted at room temperature for 2-3 hours using 95% ethanol aqueous solution as solvent. The extract was then filtered to obtain filtrate, which was freeze-dried to obtain hazel mushroom extract.

[0010] Furthermore, the ratio of hazel mushroom powder to 95% ethanol aqueous solution is 10-14g:100mL.

[0011] Furthermore, the preparation method of bamboo yellow extract is as follows: Bamboo yellow is washed, dried, and then pulverized to obtain bamboo yellow powder. The bamboo yellow powder is mixed with distilled water and extracted with water at 30-40℃ for 3-5 hours. The extract is filtered to obtain filtrate, and the filtrate is freeze-dried to obtain bamboo yellow extract.

[0012] Furthermore, the ratio of bamboo yellow powder to distilled water is 15-20g:100mL.

[0013] To achieve the above objectives, the present invention also provides a method for preparing the aforementioned anti-wrinkle and repair composition based on elastin peptides, comprising the following steps: ① Weigh out the elastin peptides, type I collagen peptides and type III collagen peptides according to the proportions, mix them evenly and set aside; ②Then add oat beta-glucan, hazelnut extract and bamboo extract and stir well.

[0014] The present invention also provides the application of an anti-wrinkle repair composition based on elastin peptides in the preparation of anti-wrinkle repair products, wherein the products are freeze-dried powders or solid beverages.

[0015] To achieve the above objectives, the present invention also provides an anti-wrinkle repair product, wherein the product is a freeze-dried powder or a solid beverage, comprising the above-mentioned anti-wrinkle repair composition.

[0016] The advantages and positive effects of the anti-wrinkle and repair composition based on elastin peptides, its preparation method, and its application described in this invention are as follows: 1. In this invention, elastin peptides and type I and III collagen peptides directly replenish collagen content and delay aging.

[0017] 2. In this invention, elastin peptides and type I and III collagen peptides work synergistically with hazel mushroom extract and bamboo extract to inhibit the formation of AGEs and the activity of MMP-1 enzyme, protecting the original collagen from damage and preventing new collagen from being glycated, thereby delaying the skin aging process and maintaining the healthy state of collagen.

[0018] The technical solution of the present invention will be further described in detail below through embodiments. Detailed Implementation

[0019] The technical solutions of the present invention are further illustrated below through embodiments. Unless otherwise defined, the technical or scientific terms used in this invention should be understood in their ordinary sense by those skilled in the art. Based on the embodiments of the present invention, all other embodiments obtained by those skilled in the art without inventive effort are within the scope of protection of the present invention. Experimental methods in the following embodiments that do not specify specific conditions are generally determined according to national standards. Experimental instruments, equipment, and reagents in the following embodiments that do not specify their sources are all commercially available raw materials.

[0020] Unless otherwise defined or stated, all technical and scientific terms used in this invention have the same meaning as those skilled in the art. Furthermore, any methods and materials similar to or equivalent to those described herein can be applied to the methods of this invention. It should be noted that, unless otherwise specified, the embodiments and features described in this invention can be combined with each other.

[0021] In this invention, hazel mushrooms and bamboo shoots were purchased from the market.

[0022] The preparation method of hazel mushroom extract in this invention is as follows: The hazel mushrooms were washed, dried, and then pulverized to obtain hazel mushroom powder. 12g of hazel mushroom powder was placed in a filter bag and extracted at room temperature for 2.5h using 100mL of 95% ethanol aqueous solution as solvent. The extract was filtered to obtain filtrate, and the filtrate was freeze-dried to obtain hazel mushroom extract.

[0023] The preparation method of bamboo extract in this invention is as follows: Bamboo yellow was washed, dried, and then pulverized to obtain bamboo yellow powder. 20g of bamboo yellow powder was mixed with 100mL of distilled water and extracted with water at 30-40℃ for 5h. The extract was filtered to obtain filtrate, and the filtrate was freeze-dried to obtain bamboo yellow extract.

[0024] In this invention, the molecular weight of the elastin peptide is less than 1000 Da, and the molecular weight of the type I collagen peptide and the type III collagen peptide is less than 2000 Da.

[0025] Example 1 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 40 parts elastin peptides, 30 parts type I collagen peptides, 30 parts type III collagen peptides, 4 parts oat β-glucan, 0.5 parts hazelnut mushroom extract, and 0.5 parts bamboo extract.

[0026] The preparation method is as follows: Weigh out elastin peptides, type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan, hazel mushroom extract and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0027] Example 2 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 45 parts elastin peptides, 25 parts type I collagen peptides, 35 parts type III collagen peptides, 4 parts oat β-glucan, 2 parts hazelnut mushroom extract, and 2 parts bamboo extract.

[0028] The preparation method is as follows: Weigh out elastin peptides, type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan, hazel mushroom extract and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0029] Example 3 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 44 parts elastin peptides, 38 parts type I collagen peptides, 36 parts type III collagen peptides, 4 parts oat β-glucan, 1 part hazelnut mushroom extract, and 1 part bamboo extract.

[0030] The preparation method is as follows: Weigh out elastin peptides, type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan, hazel mushroom extract and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0031] Example 4 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 50 parts elastin peptides, 25 parts type I collagen peptides, 28 parts type III collagen peptides, 4 parts oat β-glucan, 0.5 parts hazelnut mushroom extract, and 1 part bamboo extract.

[0032] The preparation method is as follows: Weigh out elastin peptides, type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan, hazel mushroom extract and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0033] Example 5 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 42 parts elastin peptides, 39 parts type I collagen peptides, 40 parts type III collagen peptides, 4 parts oat β-glucan, 2 parts hazelnut mushroom extract, and 1 part bamboo extract.

[0034] The preparation method is as follows: Weigh out elastin peptides, type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan, hazel mushroom extract and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0035] Comparative Example 1 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 40 parts elastin peptides, 30 parts type I collagen peptides, 0 parts type III collagen peptides, 4 parts oat β-glucan, 0.5 parts hazelnut mushroom extract, and 0.5 parts bamboo extract.

[0036] The preparation method is as follows: Weigh out elastin peptides and type I collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan, hazel mushroom extract and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0037] Comparative Example 2 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 0 parts elastin peptides, 30 parts type I collagen peptides, 30 parts type III collagen peptides, 4 parts oat β-glucan, 0.5 parts hazelnut mushroom extract, and 0.5 parts bamboo extract.

[0038] The preparation method is as follows: Weigh out type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan, hazel mushroom extract and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0039] Comparative Example 3 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 45 parts elastin peptides, 25 parts type I collagen peptides, 35 parts type III collagen peptides, 4 parts oat β-glucan, 4 parts hazelnut mushroom extract, and 0 parts bamboo extract.

[0040] The preparation method is as follows: Weigh out elastin peptides, type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan and hazelnut mushroom extract and stir evenly to obtain anti-wrinkle repair composition 1.

[0041] Comparative Example 4 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 45 parts elastin peptides, 25 parts type I collagen peptides, 35 parts type III collagen peptides, 4 parts oat β-glucan, 0 parts hazelnut mushroom extract, and 4 parts bamboo extract.

[0042] The preparation method is as follows: Weigh out elastin peptides, type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0043] Comparative Example 5 An anti-wrinkle repair composition based on elastin peptides comprises the following components in parts by weight: 45 parts elastin peptides, 25 parts type I collagen peptides, 35 parts type III collagen peptides, 4 parts oat β-glucan, 2 parts shiitake mushroom extract, and 2 parts bamboo extract.

[0044] The preparation method is as follows: Weigh out elastin peptides, type I collagen peptides and type III collagen peptides in proportion, mix them evenly and set aside; then add oat β-glucan, shiitake mushroom extract and bamboo extract and stir evenly to obtain an anti-wrinkle repair composition.

[0045] The components of the products prepared in Examples 1-5 and Comparative Examples 1-5 are shown in Table 1 (the remaining components in the table are the same): Table 1. Product components / parts by weight for Examples 1-5 and Comparative Examples 1-5

[0046] Effect test: In vitro experiments were conducted to inhibit MMP-1 in the products prepared in Examples 1-5 and Comparative Examples 1-5. Matrix metalloproteinases (MMPs) are a class of proteolytic enzymes capable of degrading the extracellular matrix. MMP-1 is a member of the MMP family and primarily degrades type I collagen. Increased MMP-1 activity leads to excessive degradation of the extracellular matrix, damaging skin structure and causing wrinkles. If a certain active ingredient can effectively inhibit MMP-1 activity, it can reduce the damage and loss of the extracellular matrix, prevent wrinkles, and achieve the purpose of anti-wrinkle and wrinkle removal. Therefore, in vitro experiments to inhibit MMP-1 were conducted to verify the anti-wrinkle effect of the products prepared in this invention.

[0047] The testing steps are as follows: 1. Solvent preparation: (1) Prepare buffer solution (50 mmol / L HEPES, 0.12 mol / L NaCl, 10 mmol / L CaCl2, 20 μmol / L ZnSO4, 0.05% Brij-35, pH=7.5).

[0048] (2) Dilute the MMP-1 proenzyme with buffer gradient to 0.22 μg / 100 μL for later use.

[0049] (3) Dilute the fluorescent substrate DQ-gelatin with buffer gradient to 0.20 μg / 100 μL for later use.

[0050] (4) Add 30 mmol of proenzyme activator APMA to 1 L of 0.1 mol / L NaOH solution to form APMA stock solution (30 mmol / L) for later use.

[0051] (5) Take the products prepared in Examples 1-5 and Comparative Examples 1-5, add distilled water to prepare a test sample solution with a concentration of 100 μg / μL for later use.

[0052] 2. Activation of MMP-1 prozymogen: MMP-1 prozymogen solution (0.22 μg / 100 μL) and APMA solution (30 mmol / L) were mixed at a volume ratio of 10:1 (MMP:APMA) and incubated at 37°C for 45 min for activation.

[0053] 3. Sample addition: Add 40 μL of activated MMP-1 solution (0.20 μg / 100 μL) to a 96-well microplate, then add 8 μL of the test solution and 52 μL of the fluorescent substrate DQ-gelatin solution (0.20 μg / 100 μL), bringing the final reaction volume to 100 μL. The sample addition system is shown in Table 2: Table 2 Sampling System

[0054] 4. Incubation at constant temperature: Place the reaction system with the added sample in a 37°C incubator for 600 seconds.

[0055] Before the reaction, the fluorescence intensity of the sample solution was detected under the detection conditions of excitation wavelength of 460 nm and emission wavelength of 520 nm. Immediately after the reaction was stopped, the fluorescence intensity of the entire reaction system was detected by a fluorescence microplate reader with excitation wavelength of 460 nm and emission wavelength of 520 nm.

[0056] MMP-1 inhibition rate (%) = [1 - (A1 - A2) / A0] × 100%; A1 represents the fluorescence intensity of the group with added plant-based active ingredients that inhibit fluorescence; A2 represents the fluorescence intensity of the active ingredient in the tested plant; A0 represents the fluorescence intensity of the blank control group.

[0057] The experiment was repeated three times, and the average was calculated. The results are shown in Table 3. Table 3 MMP-1 Inhibition Rate / %

[0058] As shown in Table 3, the MMP-1 inhibition rate of the products prepared in Examples 1-5 is all above 95%, indicating that the anti-wrinkle repair composition prepared in this invention has a significant high MMP-1 inhibition rate. This indicates that the anti-wrinkle repair composition can reduce the damage and loss of extracellular matrix, prevent the formation of wrinkles, and achieve the purpose of anti-wrinkle and wrinkle removal.

[0059] Compared with Example 1, Comparative Examples 1 and 2 showed significantly lower MMP-1 inhibition rates. Type I and Type III collagen peptides inhibited MMP-1 activity and production, while elastin peptides protected elastic fibers, synergistically inhibiting MMP-1 enzyme activity and reducing the destructive power of MMP-1 enzyme on collagen, thus achieving comprehensive protection of the core extracellular matrix (collagen network and elastic network) of the dermis.

[0060] Compared with Example 2, Comparative Examples 3 and 4 showed significantly lower MMP-1 inhibition rates, indicating that the single hazelnut extract or bamboo extract had limited inhibitory effects on MMP-1. Example 1 included both hazelnut extract and bamboo extract. Hazelnut extract, rich in polyphenols and flavonoids, possesses strong antioxidant capabilities, effectively scavenging free radicals and downregulating MMP-1 expression. Bamboo extract, a natural glycation inhibitor, inhibits MMP-1 expression by blocking glycation reactions. In Comparative Example 5, replacing hazelnut extract with shiitake mushroom extract further reduced the MMP-1 inhibition rate, demonstrating that hazelnut extract and bamboo extract synergistically inhibit MMP-1 expression, thereby suppressing MMP-1 activity, preventing wrinkle formation, and achieving anti-wrinkle effects.

[0061] Human trial: Human trials were conducted using the products prepared in Examples 1-5 and Comparative Examples 1-4. Before the trials began, a cell CCK-8 assay was performed. The results showed that the products prepared in Examples 1-5 and Comparative Examples 1-4 had no significant cytotoxicity.

[0062] Because the experimental period for edible use is relatively long, we chose to apply the composition directly to the face for rapid testing and effect analysis.

[0063] (1) Volunteer selection: 90 volunteers were selected and randomly divided into 9 groups of 10 people each. Each group of volunteers tried the products of Examples 1-5 and Comparative Examples 1-4 respectively.

[0064] The inclusion criteria for volunteers are: ① female aged 20-5 years; ② those who have not used hormone drugs or immunosuppressants in the past month; ③ those who have not participated in other clinical trials at the test site in the past 30 days; ④ those who can cooperate well with the trial; ④ those who can read and understand all the contents of the informed consent form and voluntarily sign the informed consent form; ⑤ those who agree not to use any products, drugs and health products that may affect the results during the trial.

[0065] Exclusion criteria: ① Women planning pregnancy, pregnant, breastfeeding, or within 6 months postpartum; ② Those with open wounds or erosions; ③ Those with severe allergies; ④ Those with a history of allergies; ⑤ Those with severe heart, liver, or kidney dysfunction or severe immunodeficiency; ⑥ Those with mental illness, severe endocrine disorders, or those taking oral contraceptives; ⑦ Those who have participated in drug clinical trials or other trials within the past 30 days, or those who have systematically used drugs that may affect the test results within the past week; ⑧ Those who have taken orally or topically any cosmetic products that may affect the test results within the past 2 weeks; ⑨ Those deemed unsuitable for this test by the researchers.

[0066] (2) Test method: The lyophilized powder composition was dissolved in water to prepare a lyophilized powder solution (2g / mL). Volunteers cleansed their faces with water every morning and evening, and then applied a face towel (soaked in the lyophilized powder solution) to their entire face for 7 consecutive days. The R2 value of the periorbital area (the same location before and after the test) was measured using a skin elasticity tester before and after the use. The average value was taken after 3 measurements. The R2 value is the ratio of the skin's rebound amount without negative pressure to the maximum stretch amount with negative pressure. The closer the R2 value is to 1, the better the anti-wrinkle effect. The test results are shown in Table 4.

[0067] Table 4

[0068] As shown in Table 4, the R2 increase of the anti-wrinkle repair compositions prepared in Examples 1-5 is greater than 85%, and the R2 value after use is close to 1. Compared with Examples 1-5, Comparative Examples 1-4 show a lower R2 increase, and the R2 value after use is not significantly close to 1, indicating that the compositions prepared in Examples 1-5 have better anti-wrinkle effects.

[0069] Therefore, the present invention employs the above-mentioned anti-wrinkle repair composition based on elastin peptide, its preparation method and application. The anti-wrinkle repair composition can inhibit MMP-1 enzyme activity and reduce the destructive power of MMP-1 enzyme on collagen, thereby preventing the formation of wrinkles and achieving the purpose of anti-wrinkle and wrinkle removal.

[0070] Finally, it should be noted that the above embodiments are only used to illustrate the technical solutions of the present invention and not to limit them. Although the present invention has been described in detail with reference to preferred embodiments, those skilled in the art should understand that modifications or equivalent substitutions can still be made to the technical solutions of the present invention, and these modifications or equivalent substitutions cannot cause the modified technical solutions to deviate from the spirit and scope of the technical solutions of the present invention.

Claims

1. An anti-wrinkle repair composition based on elastin peptides, characterized in that, It includes the following components by weight: 5-50 parts elastin peptide, 10-40 parts type I collagen peptide, 10-40 parts type III collagen peptide, 1-5 parts oat β-glucan, 0.1-3 parts hazelnut mushroom extract, and 0.1-3 parts bamboo extract.

2. The anti-wrinkle and repair composition based on elastin peptides according to claim 1, characterized in that, It includes the following components by weight: 40-50 parts elastin peptide, 25-40 parts type I collagen peptide, 20-40 parts type III collagen peptide, 2-4 parts oat β-glucan, 0.5-2 parts hazelnut mushroom extract, and 0.5-2 parts bamboo extract.

3. The anti-wrinkle and repair composition based on elastin peptides according to claim 1, characterized in that: The elastin peptides have a molecular weight of less than 1000 Da, and the type I and type III collagen peptides have a molecular weight of less than 2000 Da.

4. The anti-wrinkle and repair composition based on elastin peptides according to claim 1, characterized in that, The preparation method of hazel mushroom extract is as follows: The hazel mushrooms were washed, dried, and then pulverized to obtain hazel mushroom powder. The hazel mushroom powder was placed in a filter bag and extracted at room temperature for 2-3 hours using 95% ethanol aqueous solution as solvent. The extract was then filtered to obtain filtrate, which was freeze-dried to obtain hazel mushroom extract.

5. The anti-wrinkle repair composition based on elastin peptides according to claim 4, characterized in that: The ratio of hazel mushroom powder to 95% ethanol aqueous solution is 10-14g:100mL.

6. The anti-wrinkle repair composition based on elastin peptides according to claim 1, characterized in that, The preparation method of bamboo shavings extract is as follows: Bamboo yellow is washed, dried, and then pulverized to obtain bamboo yellow powder. The bamboo yellow powder is mixed with distilled water and extracted with water at 30-40℃ for 3-5 hours. The extract is filtered to obtain filtrate, and the filtrate is freeze-dried to obtain bamboo yellow extract.

7. The anti-wrinkle repair composition based on elastin peptides according to claim 6, characterized in that: The ratio of bamboo yellow powder to distilled water is 15-20g:100mL.

8. A method for preparing an anti-wrinkle repair composition based on elastin peptides according to any one of claims 1-7, characterized in that, Includes the following steps: ① Weigh out the elastin peptides, type I collagen peptides and type III collagen peptides according to the proportions, mix them evenly and set aside; ②Then add oat beta-glucan, hazelnut extract and bamboo extract and stir well.

9. The use of the anti-wrinkle repair composition based on elastin peptides according to any one of claims 1-7 in the preparation of anti-wrinkle repair products, characterized in that: The product is freeze-dried powder or solid beverage.

10. An anti-wrinkle repair product, characterized in that: The product includes an anti-wrinkle repair composition based on elastin peptides as described in any one of claims 1-7, wherein the product is a freeze-dried powder or a solid beverage.

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