A double-layer test chamber

By designing a double-layer test chamber, using the combined structure of the inner and outer cabins and corresponding mechanisms, the problems of experimental safety and accuracy of results in the prior art are solved, and safe experiments and effective purification of pathogenic pathogen bioaerosols are achieved.

CN222701604UActive Publication Date: 2025-04-01GUANGDONG HUAWEI TESTING CO LTD
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Patent Information

Application Number
CN202421409393.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-06-19
Publication Date
2025-04-01
Estimated Expiration
2034-06-19

AI Technical Summary

Technical Problem

There is a lack of a test chamber in the prior art that can safely carry out bioaerosol experiments for pathogenic pathogens, which not only prevents excessive decay of the pathogen from affecting the experimental results, but also prevents aerosol leakage from causing infection and environmental pollution.

Method used

A two-layer test chamber is designed, including an inner test chamber and an outer protective chamber, to ensure experimental safety and accuracy of experimental results through interactive mechanisms, cleaning mechanisms and environmental regulation mechanisms. The outer protective chamber is used to purify and disinfect pathogenic bioaerosols leaking from the inner test chamber to prevent them from leaking to the outside world.

Benefits of technology

On the premise of ensuring the safety of the experiment, provide a good living environment, improve the accuracy of experimental results, prevent aerosol leakage, and enhance the safety of the test chamber.

✦ Generated by Eureka AI based on patent content.

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Patent Text Reader

Abstract

The present application discloses a double-layer test chamber, including an inner test chamber, an outer protection chamber, an interaction mechanism, a cleaning mechanism and an environmental adjustment mechanism. The outer protection chamber is sleeved on the outer periphery of the inner test chamber, and a gap space is left between the outer protection chamber and the inner test chamber; the interaction mechanism is arranged through the inner test chamber and the outer protection chamber, and is sealed and connected to the inner test chamber and the outer protection chamber. The cleaning mechanism is at least arranged in the inner test chamber and the gap space, and the cleaning mechanism is used to purify or disinfect the inner test chamber and the gap space; the environmental adjustment mechanism is at least arranged in the inner test chamber and the gap space, and the environmental adjustment mechanism is at least used to adjust the temperature or humidity of the inner test chamber and the gap space. When the inner test chamber is conducting an experiment, the environmental adjustment mechanism in the inner test chamber stops running, and the environmental adjustment mechanism in the outer protection chamber keeps running.
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Description

Technical Field

[0001] The present application relates to the technical field of aerosol test equipment, and in particular to a double-layer test chamber. Background Art

[0002] In nature, there are many pathogens that are highly pathogenic to humans, and new viruses are constantly being discovered. Most of these highly pathogenic pathogens are transmitted through aerosols, which is a major threat to public health and safety, and is also the culprit for the infection of experimenters when conducting related experimental activities. At the same time, most of the pathogens cultivated in the laboratory are very fragile when directly exposed to the air in the form of aerosols, and are greatly affected by environmental factors, resulting in a high natural decay rate, which interferes with the accuracy of the experimental results.

[0003] In the related art, if the experimental device for conducting bioaerosol experiments is subjected to high-intensity purification and disinfection, it is easy to cause excessive pathogen decay during the experiment, affecting the accuracy of the experimental results; if the purification and disinfection in the device is not in place, it is easy to cause aerosol leakage, causing infection of experimenters and environmental pollution. Therefore, the prior art lacks a test chamber that can safely carry out pathogenic pathogen bioaerosol experiments. Utility Model Content

[0004] In order to solve at least one of the above technical problems, the present application provides a double-layer test chamber, which can provide a good living environment for bioaerosols during the experiment and improve the accuracy of experimental results while ensuring the safety of the experiment. The technical solution adopted is as follows.

[0005] The double-layer test chamber provided in the present application includes an inner test chamber, an outer protection chamber, an interaction mechanism, a cleaning mechanism and an environmental adjustment mechanism. The outer protection chamber is sleeved on the outer periphery of the inner test chamber, and a gap space is left between the outer protection chamber and the inner test chamber; the interaction mechanism is arranged through the inner test chamber and the outer protection chamber, and is sealed and connected to the inner test chamber and the outer protection chamber; the cleaning mechanism is at least arranged in the inner test chamber and the gap space, and the cleaning mechanism is used to purify or disinfect the inner test chamber and the gap space; the environmental adjustment mechanism is at least arranged in the inner test chamber and the gap space, and the environmental adjustment mechanism is at least used to adjust the temperature or humidity of the inner test chamber and the gap space. When conducting experiments in the inner test chamber, the environmental adjustment mechanism in the inner test chamber stops running, and the environmental adjustment mechanism in the outer protection chamber keeps running.

[0006] In certain embodiments of the present application, the interactive mechanism includes a glove module, which includes a glove channel, gloves and a glove compartment door. The side wall of the inner test compartment is provided with a first operating opening, and the outer protective compartment is provided with a second operating opening corresponding to the first operating opening. One end of the glove channel is sealed with the first operating opening, and the other end is sealed with the second operating opening. The glove is arranged in the glove channel or in the second operating opening. The glove compartment door is arranged in the inner test compartment and is used to close the first operating opening to isolate the glove from outside the inner test compartment.

[0007] In certain embodiments of the present application, the interaction mechanism further includes a sampling hole, which is disposed on the periphery of the glove module and is within an operable range of the glove module.

[0008] In some embodiments of the present application, the interactive mechanism includes a transfer window module, the transfer window module includes a transfer channel, a first window, a second window and a transfer window disinfection mechanism, the first window is arranged on the side wall of the inner test cabin, the second window is arranged on the side wall of the outer protection cabin corresponding to the first window, and both ends of the transfer channel are sealed and connected to the first window and the second window respectively;

[0009] When either the first window or the second window is opened, the other is closed. The transfer window disinfection mechanism is disposed in the transfer channel, and is used to disinfect the transfer channel and items transferred through the transfer channel.

[0010] In certain embodiments of the present application, the interactive mechanism also includes a double-door module, which includes an inner protective door, an outer protective door, a double-door channel and a double-door disinfection mechanism. The inner protective door is arranged on the side wall of the inner test chamber, and the outer protective door is arranged on the side wall of the outer protective chamber corresponding to the inner protective door. The two ends of the double-door channel are respectively sealed with the inner protective door and the outer protective door. The double-door disinfection mechanism is arranged in the double-door channel for disinfecting the double-door channel and the objects or personnel passing through the double-door channel.

[0011] In certain embodiments of the present application, the cleaning mechanism includes a purification module, which includes a filter, a speed-regulating fan and a purification pipeline. The purification pipeline is connected to the air outlet of the cabin body of the inner test cabin or the outer protective cabin. The purification pipeline includes a first branch and a second branch. The first branch is connected to the air inlet of the cabin body. The speed-regulating fan is arranged in the first branch so that the cabin body forms an airflow circulation through the first branch. The second branch is used to discharge the gas in the cabin body. The filter is arranged in the purification pipeline and is located upstream of the branch of the purification pipeline. The filter is also arranged in the first branch.

[0012] In certain embodiments of the present application, the cleaning mechanism further includes an in-cabin disinfection mechanism, and the in-cabin disinfection mechanism is disposed in the inner test chamber and in the gap space.

[0013] In certain embodiments of the present application, the cleaning mechanism further comprises a pressure monitoring device, which is disposed in the inner test cabin and the outer protective cabin and is used to detect the air pressure in the cabin;

[0014] When conducting experiments in the inner test chamber, the purification module is used to adjust the air pressure in the chamber according to the detection result of the pressure monitoring device, and make the air pressure in the outer protection chamber greater than the air pressure in the inner test chamber.

[0015] In certain embodiments of the present application, the environmental adjustment mechanism includes a constant temperature and humidity system and a temperature and humidity sensor. The temperature and humidity sensor is arranged in the inner test chamber and the gap space. The constant temperature and humidity system is arranged in the first branch. The constant temperature and humidity system is used to adjust the temperature and humidity in the inner test chamber or the outer protection chamber according to the sensing results of the temperature and humidity sensor.

[0016] In certain embodiments of the present application, the double-layer test chamber also includes a stirring mechanism, which is disposed in the inner test chamber. The stirring mechanism is installed at least on the top wall, side wall or bottom wall of the inner test chamber, and the stirring mechanism is used to stir the airflow in the inner test chamber evenly.

[0017] The embodiments of the present application have at least the following beneficial effects: by providing an inner test cabin and an outer protection cabin, the protection effect of the inner test cabin can be further increased, and the outer protection cabin can purify and disinfect the pathogenic biological aerosols leaked from the inner protection cabin, preventing the aerosols from further leaking into the external environment, thereby improving the experimental safety of the test cabin. Experimental personnel can operate experimental equipment, experimental materials, etc. in the inner test cabin through the interactive mechanism outside the outer protection cabin, or experimental materials, experimental samples, etc. can be transferred between the inner test cabin and the external environment through the interactive mechanism. By utilizing the sealed connection between the interactive mechanism and the inner and outer cabin bodies, it can be ensured that pathogenic biological aerosols leak from the connection portion between the interactive mechanism and the cabin body, thereby ensuring the safety of the double-layer test cabin.

[0018] The present application also stops the operation of the environment adjustment mechanism in the inner test chamber during the experiment, thus avoiding the impact of the environment adjustment operation on the microorganisms in the experiment (such as excessive reproduction or decay), thereby avoiding deviations in the experimental results and ensuring the accuracy of the experimental results. At the same time, the present application also continuously operates the environment adjustment mechanism in the outer protective chamber during the experiment, which helps to adjust the temperature and humidity of the inner test chamber, so that the temperature and humidity conditions of the inner test chamber are kept within a suitable range, which is helpful for the experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0019] The aspects and advantages described and / or attached in the embodiments of the present application will become apparent and easy to understand in conjunction with the following drawings. It should be noted that the embodiments embodied in the following drawings are exemplary and are only used to explain the present application, and cannot be understood as limiting the present application.

[0020] Figure 1 A schematic diagram of the structure of a double-layer test cabin provided in an embodiment of the present application;

[0021] Figure 2 A front view of a double-layer test cabin provided in an embodiment of the present application;

[0022] Figure 3 A schematic diagram of the double-deck door module structure of a double-deck test cabin provided in an embodiment of the present application;

[0023] Figure 4 A schematic diagram of the structure of a glove module provided in an embodiment of the present application;

[0024] Figure 5 A schematic diagram of the transfer window module structure provided in an embodiment of the present application.

[0025] Reference numerals:

[0026] 100, double-layer test chamber; 10, inner test chamber; 20, outer protective chamber; 30, interactive mechanism; 31, glove module; 311, glove chamber door; 312, second operating opening; 313, door handle; 32, sampling hole; 33, transfer window module; 331, transfer channel; 332, first window; 333, second window; 334, transfer window disinfection mechanism; 34, double-layer door module; 341, inner protective door; 342, outer protective door; 343, double-layer door passage duct; 344, double-door disinfection mechanism; 35, observation window; 40, cleaning mechanism; 41, purification module; 411, filter; 4111, filter built-in disinfection mechanism; 412, speed-adjusting fan; 413, purification pipeline; 4131, first branch; 4132, second branch; 4133, solenoid valve; 42, cabin disinfection mechanism; 43, pressure monitoring device; 50, environmental adjustment mechanism; 51, constant temperature and humidity system; 52, temperature and humidity sensor; 60, stirring mechanism. DETAILED DESCRIPTION

[0027] Combine the following Figures 1 to 5 Embodiments of the present application are described in detail, and examples of the embodiments are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present application, and cannot be understood as limiting the present application.

[0028] In the description of the present application, it should be understood that if the terms "center", "middle", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "axial", "radial", "circumferential" and the like appear, the orientation or position relationship indicated is based on the orientation or position relationship shown in the drawings, which is only for the convenience of describing the present application and simplifying the description, and does not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present application. In addition, the features defined as "first" and "second" may explicitly or implicitly include one or more of the features. In the description of the present application, unless otherwise specified, "multiple" means two or more.

[0029] In the description of this application, it should be noted that, unless otherwise clearly specified and limited, the terms "installed", "connected", and "connected" should be understood in a broad sense, for example, it can be a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection, or it can be indirectly connected through an intermediate medium, or it can be the internal communication of two components. For ordinary technicians in this field, the specific meanings of the above terms in this application can be understood according to specific circumstances.

[0030] See also Figures 1 to 3 The present application provides a double-layer test chamber 100, comprising an inner test chamber 10, an outer protection chamber 20, an interaction mechanism 30, a cleaning mechanism 40 and an environment adjustment mechanism 50. The outer protection chamber 20 is sleeved on the outer periphery of the inner test chamber 10, and a gap space is left between the outer protection chamber 20 and the inner test chamber 10; the interaction mechanism 30 is arranged through the inner test chamber 10 and the outer protection chamber 20, and is sealed and connected to the inner test chamber 10 and the outer protection chamber 20. The cleaning mechanism 40 is at least arranged in the inner test chamber 10 and the gap space, and the cleaning mechanism 40 is used to purify or disinfect the inner test chamber 10 and the gap space; the environment adjustment mechanism 50 is at least arranged in the inner test chamber 10 and the gap space, and the environment adjustment mechanism 50 is at least used to adjust the temperature or humidity of the inner test chamber 10 and the gap space. When the inner test chamber 10 is conducting an experiment, the environment adjustment mechanism 50 in the inner test chamber 10 stops running, and the environment adjustment mechanism 50 in the outer protection chamber 20 keeps running.

[0031] By setting up the inner test cabin 10 and the outer protection cabin 20, the protection effect can be further increased on the basis of the protection of the inner test cabin 10. The outer protection cabin 20 can purify and disinfect the pathogenic biological aerosol leaked from the inner protection cabin, prevent the aerosol from further leaking into the external environment, and improve the experimental safety of the test cabin. Since two layers of cabins are set up, when it is necessary to perform experimental operations in the cabin, it is necessary to pass through the two cabins at the same time. Therefore, the present application also sets up an interactive mechanism 30, which runs through the inner test cabin 10 and the outer protection cabin 20. In this way, the experimenter can operate the experimental equipment, experimental materials, etc. in the inner test cabin 10 through the interactive mechanism 30 outside the outer protection cabin 20, or experimental materials, experimental samples, etc. can be transferred between the inner test cabin 10 and the external environment through the interactive mechanism 30. By using the sealed connection between the interactive mechanism 30 and the inner and outer cabins, it can be ensured that the pathogenic biological aerosol leaks from the connection part between the interactive mechanism 30 and the cabin, and the safety of the double-layer test cabin 100 is ensured. For pathogenic microorganisms, especially those with high pathogenicity and great harm to experimenters, the double-layer test chamber 100 provided by the present application can not only prevent the leakage of microbial aerosols and ensure the safety of the environment, but also, most importantly, provide protection for experimenters. The protective effect of the two-layer chamber can further improve the safety performance of the test chamber and avoid infection of experimenters. Therefore, the double-layer test chamber 100 provided by the present application can meet the needs of conducting pathogenic microbial aerosol experiments.

[0032] The present application also stops the operation of the environment adjustment mechanism 50 in the inner test chamber 10 during the experiment, so as to avoid the influence of the environment adjustment operation on the microorganisms in the experiment (for example, the filter suction and filtering action lead to a significant reduction of microorganisms), thereby avoiding the deviation of the experimental results and ensuring the accuracy of the experimental results. At the same time, the present application also continuously operates the environment adjustment mechanism 50 of the outer protective chamber 20 during the experiment, which helps to adjust the temperature and humidity of the inner test chamber 10, so that the temperature and humidity conditions of the inner test chamber 10 are kept in a suitable range, which helps to carry out the experiment. It should be emphasized that the inner test chamber 10 and the outer protective chamber 20 are not connected to each other. Therefore, the temperature and humidity adjustment process of the outer protective chamber 20 can indirectly adjust the temperature and humidity of the inner test chamber 10. This indirect adjustment can stabilize the experimental environment of the inner test chamber 10 within a suitable range without affecting the experimental environment in the inner test chamber 10 and avoiding large fluctuations in the experimental environment, which helps to improve the accuracy of the experimental results.

[0033] It can be understood that the cleaning mechanism 40 and the environmental adjustment mechanism 50 are at least partially arranged in the inner test chamber 10 and the gap space, which means that since the cleaning mechanism 40 includes but is not limited to the purification module 41 and the disinfection mechanism, and the environmental adjustment mechanism 50 includes but is not limited to the constant temperature and humidity system 51 and the temperature and humidity sensor 52, the above structures can be all arranged in the space inside the chamber, or part of them can be arranged in the chamber and the other part can be arranged outside the chamber, so as to save the space inside the chamber. For these structures arranged outside the chamber, they can still act on the space inside the chamber through the pipes connected to the chamber, which is not limited here.

[0034] Optionally, the cleaning mechanism 40 and the environmental adjustment mechanism 50 provided in the inner test chamber 10 and the outer protection chamber 20 may have the same or different structures, working principles, and working modes. In the following examples, the inner test chamber 10 and the outer protection chamber 20 using the same cleaning mechanism 40 and environmental adjustment mechanism 50 will be used as an example for explanation. Therefore, when the inner test chamber 10 or the outer protection chamber 20 is not specifically referred to, the chamber body refers to the inner test chamber 10 and the outer protection chamber 20.

[0035] In some embodiments, see Figure 2 and Figure 4 The interaction mechanism 30 includes a glove module 31, which includes a glove channel (not shown), gloves (not shown) and a glove compartment door 311. The side wall of the inner test cabin 10 is provided with a first operation opening, and the outer protective cabin 20 is provided with a second operation opening 312 corresponding to the first operation opening. One end of the glove channel is sealed with the first operation opening, and the other end is sealed with the second operation opening 312. The gloves are arranged in the glove channel or the second operation opening 312. The glove compartment door 311 is arranged in the inner test cabin 10 and is used to close the first operation opening so that the gloves are isolated from the inner test cabin 10. By providing the glove module 31, under the premise of ensuring the sealed protection of the cabin, the experimenter can reach into the inner test cabin 10 through the gloves outside the outer protective cabin 20, so as to perform experimental operations on the space inside the inner test cabin 10, such as operating the experimental instruments and experimental equipment in the cabin, moving or placing the experimental samples, etc. By using the first operation opening and the second operation opening 312 to be sealed with the glove channel respectively, it is possible to prevent the pathogenic biological aerosol from leaking into the external environment through the two operation openings. By providing the glove compartment door 311, the gloves can be isolated from the inner test compartment 10 after the glove operation is completed, so as to prevent the gas in the inner test compartment 10 from entering the gloves and causing glove contamination, or to protect the gloves from oxidation and corrosion by the strong oxidizing products in the inner test compartment 10, thereby improving the safety of use and the service life of the gloves.

[0036] For example, the gloves can be fixed in the second operating opening 312 by means of a mounting hoop, which can reduce the difficulty of installing the gloves. The glove compartment door 311 can be provided with an emergency door handle 313 for locking, so that when the glove compartment door 311 is closed, the sealing between the glove compartment door 311 and the first operating opening can be ensured, thereby improving the protective performance of the glove module 31.

[0037] In some embodiments, the interactive mechanism 30 further includes a sampling hole 32, which is disposed on the periphery of the glove module 31 and is within the operable range of the glove module 31. By using the sampling hole 32, the experimenter can obtain the experimental samples in the chamber without entering the inner test chamber 10 during the experiment, thereby ensuring the safety of the sampling operation, and avoiding interference to the experimental environment of the inner test chamber 10 caused by the experimenter's entry and exit actions, thereby improving the accuracy of the experimental results.

[0038] Optionally, the sampling holes 32 can be multiple and arranged around the glove module 31, such as the upper side, lower side, left side, right side, etc. of the glove module 31. The specific setting position can be flexibly set according to the needs of the experimental operation. When using the sampling holes 32, the sampling holes 32 at the corresponding positions can also be flexibly opened according to the specific experimental operation needs. By setting the sampling holes 32 within the operable range of the glove module 31, it can be ensured that there is a suitable distance between the sampling holes 32 and the glove module 31, ensuring the convenience of the sampling operation. Figure 2 In the example shown, the sampling hole 32 is disposed above the glove module 31, and the experimenter can insert his hand into the glove and perform sampling operation with his hand facing upward.

[0039] In some embodiments, in order to facilitate observation during the sampling process, the interactive mechanism 30 is also provided with an observation window 35, which can penetrate the two layers of the cabin to ensure that the experimenter can observe and monitor the situation in the inner test cabin 10 through the observation window 35.

[0040] In some embodiments, the interactive mechanism 30 includes a transfer window module 33, the transfer window module 33 includes a transfer channel 331, a first window 332, a second window 333 and a transfer window disinfection mechanism 334, the first window 332 is arranged on the side wall of the inner test cabin 10, the second window 333 is arranged on the side wall of the outer protective cabin 20 corresponding to the first window 332, and the two ends of the transfer channel 331 are sealed and connected to the first window 332 and the second window 333 respectively. When either the first window 332 or the second window 333 is opened, the other is closed, and the transfer window disinfection mechanism 334 is arranged in the transfer channel 331, and the transfer window disinfection mechanism 334 is used to disinfect the transfer channel 331 and the items transferred through the transfer channel 331. Through the transfer window module 33, items such as sampling equipment, experimental equipment, experimental materials or samples can be transferred inside and outside the inner test cabin 10. By setting up the transfer channel 331, and the first window 332 and the second window 333 cannot be opened at the same time, in this way, during the process of transferring the items, the transfer channel 331 can be used as a buffer area for temporarily storing items. By setting up the transfer window disinfection mechanism 334 to disinfect the area, the items can be disinfected before entering the inner test chamber 10 or leaving the outer protection chamber 20, thereby preventing the items from bringing external pollution sources into the inner test chamber 10 to cause pollution of the experimental environment and affect the accuracy of the experimental results. At the same time, it also prevents the items from bringing pollutants in the experimental environment out of the outside world, causing the leakage of pathogens, polluting the external environment or infecting experimental personnel, thereby improving the safety of the use of the double-layer test chamber 100.

[0041] Optionally, the disinfection mechanism of the transfer channel 331 can use an ultraviolet lamp or spray a disinfectant to achieve disinfection. The first window 332 and the second window 333 can be set as transparent windows to facilitate observation of the cabin situation of the inner test cabin 10 when transferring items. Exemplarily, the first window 332 and the second window 333 can be controlled by an electronic interlocking device, and an infrared sensing device is set to detect the opening and closing status of the first window 332 and the second window 333. Exemplarily, when it is necessary to transfer items to the inner test cabin 10, the second window 333 is opened first, and the items are placed in the transfer channel 331. During this placement process, the first window 332 remains closed. After the items are placed, the second window 333 is closed. The transfer window disinfection mechanism 334 is turned on to disinfect the items and the transfer channel 331, and then the first window 332 is opened, and the second window 333 remains closed. The experimenter uses the glove operation module to operate the items to enter the inner test chamber 10, or the items enter the inner test chamber 10 by themselves through automatic control or remote control, and then the first window 332 is closed again. At this time, the transfer window disinfection mechanism 334 can be turned on again to disinfect the transfer channel 331. The operation method of the item removal process is opposite to that of the item placement process, which will not be repeated here.

[0042] In some embodiments, the interactive mechanism 30 further includes a double-layer door module 34, which includes an inner protective door 341, an outer protective door 342, a double-layer door passage 343 and a double-layer door disinfection mechanism 344. The inner protective door 341 is arranged on the side wall of the inner test cabin 10, and the outer protective door 342 is arranged on the side wall of the outer protective cabin 20 corresponding to the inner protective door 341. The two ends of the double-layer door passage 343 are respectively sealed and connected with the inner protective door 341 and the outer protective door 342. The double-layer door disinfection mechanism 344 is arranged in the double-layer door passage 343, and is used to disinfect the double-layer door passage 343 and the objects or personnel passing through the double-layer door passage 343. The double-layer door passage 343 can allow experimenters to enter or leave the inner test cabin 10, and prepare for experiments or clean up after experiments in the cabin. The double-door disinfection mechanism 344 can also disinfect and clean the double-door passage 343 and the experimenter, ensuring that the experimenter is not infected by pathogenic organisms, and preventing the experimenter from taking out the pathogenic organisms in the inner test chamber 10 when leaving. The opening and closing principle of the double-door passage 343 is the same as that of the transfer window module 33, and its operation steps are similar to the opening and closing steps of the transfer window, which will not be repeated here.

[0043] Optionally, each module in the above-mentioned interactive mechanism 30 can be arranged on the same side wall of the double-layer test chamber 100, and each module can be arranged at intervals from each other, and a smaller gap can be set in the gap space corresponding to the side wall, which is conducive to shortening the distance between the sides of the two chambers and reducing the difficulty of interactive operation. The remaining side walls of the double-layer test chamber 100 can be set with a larger gap, and the gap can be used to obtain sufficient space to install the cleaning mechanism 40 or the environmental adjustment mechanism 50.

[0044] The cleaning mechanism 40 and the environment adjustment mechanism 50 will be introduced in detail below.

[0045] In some embodiments, the cleaning mechanism 40 includes a purification module 41, the purification module 41 includes a filter 411, a speed-adjusting fan 412 and a purification pipeline 413, the purification pipeline 413 is connected to the air outlet of the cabin of the inner test cabin 10 or the outer protective cabin 20, the purification pipeline 413 includes a first branch 4131 and a second branch 4132, the first branch 4131 is connected to the air inlet of the cabin, the speed-adjusting fan 412 is arranged in the first branch 4131, so that the cabin forms an airflow circulation through the first branch 4131, the second branch 4132 is used to discharge the gas in the cabin, the filter 411 is arranged in the purification pipeline 413 and is located upstream of the branch of the purification pipeline 413, and the filter 411 is also arranged in the first branch 4131. Using the purification module 41, the gas in the cabin can be circulated and purified. The gas in the cabin has two directions after leaving the cabin, one of which is to return to the cabin after purification through the first branch 4131, so that the airflow circulation is formed in the cabin. In the process of forming an airflow cycle, the gas is filtered through the filter 411, which can intercept the pathogenic biological particles in the aerosol, and the gas after removing the pathogenic biological particles returns to the cabin, achieving a purification effect in the cabin. Another direction of the gas is to leave the cabin using the second branch 4132, which can achieve a ventilation effect for the cabin. Before entering the second branch 4132, the gas is first purified by the filter 411. After leaving the second branch 4132, it can also enter the centralized exhaust gas treatment equipment for further purification to ensure the safety of emissions. The speed-regulating fan 412 can be used to adjust the air volume and wind speed of the cabin intake, realize the adjustment of the cabin pressure, and meet the experimental needs and safety protection needs.

[0046] Optionally, the filter 411 may be provided with an ultraviolet disinfection device, such as an ultraviolet lamp, and the pathogenic organisms intercepted in the filter 411 may be further disinfected by the radiation of the ultraviolet lamp, thereby eliminating the activity of the pathogenic biological particles in the filter 411 and improving the filtering and purification effect of the filter 411. As an example, a solenoid valve 4133 may be provided in the first branch 4131 and the second branch 4132, respectively, so as to control the connection or closing of the branch and realize the control of the gas flow direction in the cabin. According to actual needs, one or more speed-regulating fans 412 may be provided in the first branch 4131, and the speed-regulating fans 412 may be provided upstream of the first branch 4131 or near the air inlet of the cabin. Exemplarily, the purification module 41 may be started before the experiment and after the experiment to ensure that the cabin environment before the experiment can meet the initial conditions of the experiment, and to ensure that the cabin environment can be purified in time after the experiment, to ensure the cleanliness and safety of the cabin, and to avoid infection of the experimenters and pollution of the environment. Of course, during the experiment, the purification module 41 can be started or stopped according to the experiment type, experiment purpose and other requirements.

[0047] In some embodiments, the cleaning mechanism 40 further includes an in-cabin disinfection mechanism 42, which is disposed in the inner test chamber 10 and in the gap space. In this way, the in-cabin disinfection mechanism 42 can be used to disinfect pathogenic organisms in the chamber, thereby achieving a disinfection effect in the chamber. Exemplarily, the in-cabin disinfection mechanism 42 can be an ultraviolet lamp, or other equipment that can release disinfectants.

[0048] In some embodiments, the environment adjustment mechanism 50 includes a constant temperature and humidity system 51 and a temperature and humidity sensor 52. The temperature and humidity sensor 52 is arranged in the inner test chamber 10 and the gap space. The constant temperature and humidity system 51 is arranged in the first branch 4131. The constant temperature and humidity system 51 is used to adjust the temperature and humidity in the inner test chamber 10 or the outer protection chamber 20 according to the sensing result of the temperature and humidity sensor 52. By setting the constant temperature and humidity system 51, the environment in the chamber can be kept in a suitable temperature and humidity range, which helps to provide a good experimental environment. Specifically, during the experiment, the constant temperature and humidity system 51 of the inner test chamber 10 can stop running, while the constant temperature and humidity system 51 of the outer protection chamber 20 keeps running. In this way, the environmental adjustment operation in the inner test chamber 10 can avoid the impact on the microorganisms in the experiment (such as excessive reproduction or decay), thereby avoiding deviations in the experimental results and ensuring the accuracy of the experimental results. In the outer protection cabin 20, the operation of the constant temperature and humidity system 51 can maintain appropriate temperature and humidity conditions in the outer protection cabin 20, which helps to adjust the temperature and humidity of the inner test cabin 10, so that the temperature and humidity conditions of the inner test cabin 10 are maintained in an appropriate range, which is helpful for the experiment. Of course, in other examples, the constant temperature and humidity system 51 of the inner test cabin 10 can also be turned on during the experiment according to the experimental needs to meet the requirements of the experimental conditions, which is not limited here.

[0049] It can be understood that the constant temperature and humidity system 51 can not only be set in the first path to reduce the space occupied in the cabin, but also in other examples, the constant temperature and humidity system 51 can be set in the cabin to achieve regulation and control of the temperature and humidity of the cabin.

[0050] In some embodiments, the cleaning mechanism 40 further includes a pressure monitoring device 43, which is provided in the inner test cabin 10 and the outer protection cabin 20 and is used to detect the air pressure in the cabin; when the inner test cabin 10 is conducting an experiment, the purification module 41 is used to adjust the air pressure in the cabin according to the detection result of the pressure monitoring device 43, and make the air pressure of the outer protection cabin 20 greater than the air pressure of the inner test cabin 10. By providing the pressure monitoring device 43, such as a pressure sensor, etc., it is helpful to accurately detect the pressure in the cabin, and the purification module 41 can adjust the operating power of the speed regulating fan 412 based on this, so as to achieve the air pressure regulation in the cabin. By setting the air pressure of the outer protection cabin 20 to be greater than the air pressure of the inner test cabin 10, it is helpful to prevent the aerosol of the inner test cabin 10 from overflowing to the outer protection cabin 20, thereby preventing the pathogenic microorganism aerosol in the inner test cabin 10 from leaking and causing human infection or environmental pollution, and improving the use safety and reliability of the double-layer test cabin 100.

[0051] In some embodiments, the double-layer test chamber 100 further includes a stirring mechanism 60, which is disposed in the inner test chamber 10. The stirring mechanism 60 is installed at least on the top wall, side wall or bottom wall of the inner test chamber 10. The stirring mechanism 60 is used to stir the airflow in the inner test chamber 10 uniformly. The stirring mechanism 60 can be used to strengthen the airflow in the inner test chamber 10, and achieve the effect of uniform distribution of aerosol in the inner test chamber 10. According to the requirements of the experimental setting, the stirring mechanism 60 can be turned on before or during the experiment. Exemplarily, the stirring mechanism 60 includes a fan, and when the fan is disposed on the top wall of the inner test chamber 10, it can be in the form of a ceiling fan, and when the fan is disposed on the side wall of the inner test chamber 10, it can be installed in a wall-mounted form, or the fan can be disposed on the floor of the inner test chamber 10 in a floor-standing form, or the fan can be placed in the corner of the inner test chamber 10 in a floor-standing form, so as to achieve the effect of uniform stirring of aerosol in the entire inner test chamber 10.

[0052] The double-layer test chamber 100 provided in the present application can be used to carry out performance testing of purification products or to study the movement patterns of virus aerosol droplets in indoor environments. Of course, the types of experiments that can be carried out in the double-layer test chamber 100 are not limited to the above two types. The two experiments are introduced separately below.

[0053] Example 1

[0054] The double-layer test chamber 100 can be used to test the removal effect of the purification product on influenza virus, as follows:

[0055] First, purification products, aerosol generators and other experimental equipment are placed in two double-layer test chambers 100 provided by the present application at one time, one of the double-layer test chambers 100 is used as a test group, and the other is used as a control group.

[0056] After the cabin door is closed, the purification module 41 is turned on to control the cleanliness level in the double-layer test cabin 100 to reach above Class 10,000.

[0057] Set the initial temperature and humidity conditions, and set the target temperature and humidity of the two double-layer test chambers 100 to 20-23°C and 60-70%RH. Turn on the constant temperature and humidity system 51, and monitor through the pressure monitoring device 43, adjust the pressure of the inner test chamber 10 to normal pressure 0Pa, and the pressure of the outer protective chamber 20 to +10Pa.

[0058] After all the above conditions are met, the purification module 41 and the constant temperature and humidity system 51 of the inner test cabin 10 are turned off, but the purification module 41 and the constant temperature and humidity system 51 of the outer protection cabin 20 remain in operation. The stirring mechanism 60 is turned on and the aerosol generator is turned on to stir and atomize at the same time. After the atomization is completed, the stirring system continues to stir for 5 minutes, and then is turned off and left to stand for 5 minutes, so that the generated aerosol can evenly fill the entire space of the inner test cabin 10. The sampler is used to sample the initial concentration of the cabins of the test group and the control group through the sampling hole 32 and start counting the time.

[0059] After the purified product has been used for the set experimental time, the sampler is used again to sample the final concentration of the test group and the control group. The sampler is transferred through the transfer window module 33, and the transfer window ultraviolet lamp is turned on for disinfection after the transfer. During the experiment, the control group is kept the same as the test group except that the purified product to be tested is not run.

[0060] The collected samples were diluted in series, and the dilutions were added to the cell culture plate and transferred to a carbon dioxide incubator. The cells were cultured at 37°C and 5% CO2 for 3 to 5 days. The cell growth was observed every day, the pathological changes were recorded, and the TCID of the tissue was calculated. 50 .

[0061] After the experiment, the cabin disinfection mechanism 42 of the inner test cabin 10 is turned on to disinfect the test group for more than one hour. After the disinfection is completed, the cabin disinfection mechanism 42 of the inner test cabin 10 is first closed, then the cabin disinfection mechanism 42 of the outer protection cabin 20 is closed, and finally the purification module 41 of the outer protection cabin 20 is closed.

[0062] Example 2

[0063] The double-layer test chamber 100 can also be used for research experiments on the movement patterns of virus aerosol droplets in indoor environments, as follows:

[0064] Install the virus suspension of appropriate concentration on a tripod and connect it to a human respiratory tract and lung simulator, which can simulate the strength of a person's coughing, sneezing, and breathing, giving the aerosol droplets a suitable initial velocity and pressure. Five sampling points are arranged every 0.5m horizontally at positions of 0.5m, 1m, 1.5m, 2m, 2.5m, and 3m from the launch end, for a total of thirty sampling points.

[0065] After the above work is prepared, close the cabin door and then turn on the purification module 41, control the cleanliness level in the inner test cabin 10 to reach above Class 10, set the target temperature and humidity of the inner test cabin 10 and the outer protection cabin 20 to 20-23°C, and the humidity to 60-70% RH, then turn on the constant temperature and humidity system 51, and adjust the pressure of the inner test cabin 10 to normal pressure 0Pa and the pressure of the outer protection cabin 20 to +10Pa through the pressure monitoring device 43.

[0066] After all the above conditions are met, the purification module 41 and the constant temperature and humidity system 51 of the inner test cabin 10 are turned off, but the purification module 41 and the constant temperature and humidity system 51 of the outer protection cabin 20 remain in operation. The simulator is operated to simulate human coughing, sneezing, and breathing, and the sampling liquid is collected for analysis after 5 minutes, 10 minutes, 15 minutes, 20 minutes, and 30 minutes respectively.

[0067] The recovered solution was diluted in a gradient manner, added to the cell culture plate and transferred to a carbon dioxide incubator, cultured at 37°C, 5% CO2 for 3-5 days, and the cell growth was observed every day, the pathological changes were recorded, and the half tissue infection dose TCID was calculated. 50 .

[0068] After the experiment, the cabin disinfection mechanism 42 of the inner test cabin 10 and the outer protection cabin 20 is opened for disinfection for more than one hour. After the disinfection is completed, the cabin disinfection mechanism 42 of the inner test cabin 10 is closed first, then the cabin disinfection mechanism 42 of the outer protection cabin 20 is closed, and finally the purification module 41 of the outer protection cabin 20 is closed.

[0069] In the description of this specification, if the reference terms "one embodiment", "some examples", "some embodiments", "illustrative embodiment", "example", "specific example", or "some examples" appear, it means that the specific features, structures, materials or characteristics described in conjunction with the embodiment or example are included in at least one embodiment or example of the present application. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner.

[0070] The above describes the implementation methods of the present application in detail in conjunction with the accompanying drawings, but the present application is not limited to the above implementation methods. Various changes can be made within the knowledge scope of ordinary technicians in the technical field without departing from the purpose of the present application.

[0071] In the description of this application, if "," appears in the patent name, it means an "and" relationship, not an "or" relationship. For example, if the patent name is "a kind of A, B", it means that the content required to be protected by this application is: the technical solution with the subject name A and the technical solution with the subject name B.

Claims

1. A double-layer test cabin, characterized in that: include An inner test cabin and an outer protection cabin, wherein the outer protection cabin is sleeved on the outer periphery of the inner test cabin, and a gap space is left between the outer protection cabin and the inner test cabin; An interactive mechanism, wherein the interactive mechanism is disposed through the inner test cabin and the outer protection cabin and is sealedly connected to the inner test cabin and the outer protection cabin; A cleaning mechanism, the cleaning mechanism is at least arranged in the inner test chamber and the gap space, and the cleaning mechanism is used to purify or disinfect the inner test chamber and the gap space; An environmental regulating mechanism is at least arranged in the inner test chamber and the gap space, and is used at least to regulate the temperature or humidity of the inner test chamber and the gap space. When conducting experiments in the inner test chamber, the environmental regulating mechanism in the inner test chamber stops running, and the environmental regulating mechanism in the outer protective chamber keeps running.

2. The double-layer test cabin according to claim 1 is characterized in that: The interactive mechanism includes a glove module, which includes a glove channel, gloves and a glove compartment door. The side wall of the inner test compartment is provided with a first operating opening, and the outer protective compartment is provided with a second operating opening corresponding to the first operating opening. One end of the glove channel is sealed with the first operating opening, and the other end is sealed with the second operating opening. The glove is arranged in the glove channel or in the second operating opening. The glove compartment door is arranged in the inner test compartment and is used to close the first operating opening to isolate the glove from outside the inner test compartment.

3. The double-layer test cabin according to claim 2 is characterized in that: The interactive mechanism further includes a sampling hole, which is disposed on the periphery of the glove module and is within an operable range of the glove module.

4. The double-layer test cabin according to claim 1 is characterized in that: The interactive mechanism comprises a transfer window module, the transfer window module comprises a transfer channel, a first window, a second window and a transfer window disinfection mechanism, the first window is arranged on the side wall of the inner test cabin, the second window is arranged on the side wall of the outer protection cabin corresponding to the first window, and both ends of the transfer channel are sealed and connected to the first window and the second window respectively; When either the first window or the second window is opened, the other is closed. The transfer window disinfection mechanism is disposed in the transfer channel, and is used to disinfect the transfer channel and items transferred through the transfer channel.

5. The double-layer test cabin according to claim 1 is characterized in that: The interactive mechanism also includes a double-door module, which includes an inner protective door, an outer protective door, a double-door passage and a double-door disinfection mechanism. The inner protective door is arranged on the side wall of the inner test cabin, and the outer protective door is arranged on the side wall of the outer protective cabin corresponding to the inner protective door. The two ends of the double-door passage are respectively sealed with the inner protective door and the outer protective door. The double-door disinfection mechanism is arranged in the double-door passage for disinfecting the double-door passage and the objects or personnel passing through the double-door passage.

6. The double-deck test cabin according to any one of claims 1 to 5, characterized in that: The cleaning mechanism includes a purification module, which includes a filter, a speed-regulating fan and a purification pipeline. The purification pipeline is connected to the air outlet of the cabin body of the inner test cabin or the outer protection cabin. The purification pipeline includes a first branch and a second branch. The first branch is connected to the air inlet of the cabin body. The speed-regulating fan is arranged in the first branch so that the cabin body forms an air flow circulation through the first branch. The second branch is used to discharge the gas in the cabin body. The filter is arranged in the purification pipeline and is located upstream of the branch of the purification pipeline. The filter is also arranged in the first branch.

7. The double-layer test cabin according to claim 6 is characterized in that: The cleaning mechanism also includes an in-cabin disinfection mechanism, which is arranged in the inner test chamber and in the gap space.

8. The double-layer test cabin according to claim 6 is characterized in that: The cleaning mechanism further comprises a pressure monitoring device, which is arranged in the inner test cabin and the outer protection cabin and is used to detect the air pressure in the cabin; When conducting experiments in the inner test chamber, the purification module is used to adjust the air pressure in the chamber according to the detection result of the pressure monitoring device, and make the air pressure in the outer protection chamber greater than the air pressure in the inner test chamber.

9. The double-layer test cabin according to claim 6, characterized in that: The environmental adjustment mechanism includes a constant temperature and humidity system and a temperature and humidity sensor. The temperature and humidity sensor is arranged in the inner test chamber and the gap space. The constant temperature and humidity system is arranged in the first branch. The constant temperature and humidity system is used to adjust the temperature and humidity in the inner test chamber or the outer protection chamber according to the sensing results of the temperature and humidity sensor.

10. The double-deck test chamber according to any one of claims 1 to 5, characterized in that: The double-layer test chamber also includes a stirring mechanism, which is arranged in the inner test chamber. The stirring mechanism is installed at least on the top wall, side wall or bottom wall of the inner test chamber, and is used to stir the airflow in the inner test chamber evenly.