Optical detection device for fluorescence analyzer

By using a ring light source in the fluorescence analyzer, the problem of weak fluorescence caused by the optical detection module in the prior art can only emit a single beam, achieving a more efficient detection effect.

CN222748492UActive Publication Date: 2025-04-11苏州康医诺生物科技有限公司
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Patent Information

Application Number
CN202421056910.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-05-15
Publication Date
2025-04-11
Estimated Expiration
2034-05-15

AI Technical Summary

Technical Problem

The optical detection module of existing fluorescence analyzers can only emit a single detection beam, resulting in very weak excitation fluorescence, affecting the detection effect of the sample.

Method used

An optical detection device for a fluorescence analyzer is designed, using an annular light source and an LED light source are arranged along the circular annular trajectory of the light source shell, and the spot area covers the entire area to be detected to ensure a uniformity of more than 95%.

Benefits of technology

Through the design of the ring light source, it is possible to expose and capture clear and recognizable images in a short time, improving the detection sensitivity and detection speed.

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Abstract

The utility model discloses an optical detection device of a fluorescence analyzer, comprising a base and a reference bracket fixed on the base, a camera and an annular light source are installed on the reference bracket, the camera and the annular light source are arranged along the vertical direction of the reference bracket, the annular light source is located below the camera, the lens end of the camera passes through the inner ring of the annular light source and faces the detection area, the annular light source comprises a light source housing and a plurality of LED light sources, the plurality of LED light sources are arranged at an angle on the shell wall of the light source housing facing the detection area, and the plurality of LED light sources are arranged along the circular track of the light source housing. The light spot area of ​​the utility model can cover the entire detection area of ​​the fluorescence analyzer, and can capture clear and recognizable images in a short exposure time, thereby improving the detection sensitivity and detection speed.
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Description

Technical Field

[0001] The utility model relates to the technical field of fluorescence analyzer equipment, and more specifically, to an optical detection device of a fluorescence analyzer. Background Art

[0002] Immunofluorescence analyzer is an analytical instrument based on immunology and fluorescence technology. It has a wide range of applications in medical diagnosis, biological research and environmental monitoring. Immunofluorescence analyzer is an advanced instrument based on immunology and fluorescence technology. Immunology uses the specific recognition and binding mechanism of the immune system of organisms to detect specific biological molecules or pathogens through the specific binding of antibodies and antigens. Fluorescence technology uses the characteristics of fluorescent probes to emit fluorescent signals under the action of excitation light, and determines the presence and concentration of the substance to be detected by measuring the intensity of the fluorescent signal. The optical system plays a key role in the immunofluorescence analyzer, including components such as excitation light source, optical lens, filter and detector.

[0003] At present, due to the limitations of the structural design of existing fluorescence analyzers, the optical detection module in the existing fluorescence analyzers can often only emit a single detection light beam, resulting in very weak excited fluorescence, which greatly affects the detection effect of the sample.

[0004] Therefore, how to solve the deficiencies in the above-mentioned prior art has become a topic to be studied and solved in this application. Utility Model Content

[0005] In view of this, an object of the present utility model is to provide an optical detection device for a fluorescence analyzer.

[0006] In order to achieve the above purpose, the technical solution adopted by the utility model is:

[0007] An optical detection device for a fluorescence analyzer, comprising a base and a reference bracket fixed on the base, a camera and an annular light source are mounted on the reference bracket, the camera and the annular light source are both arranged along the vertical direction of the reference bracket, and the annular light source is located below the camera; the lens end of the camera passes through the inner ring of the annular light source and faces the area to be detected;

[0008] The annular light source comprises a light source housing and a plurality of LED light sources. The plurality of LED light sources are arranged at an angle on a shell wall of the light source housing facing the area to be detected, and the plurality of LED light sources are arranged along a circular track of the light source housing.

[0009] Furthermore, the lens end of the camera is coaxial with the area to be detected.

[0010] Furthermore, an adjustment platform is installed on the reference bracket, and the camera is installed on the adjustment platform.

[0011] Furthermore, a light shield is installed on the reference bracket, and the light shield is sleeved on the annular light source.

[0012] Furthermore, the light spot area of ​​the annular light source covers the area to be detected.

[0013] Furthermore, a cooling fan is installed on the reference bracket.

[0014] Furthermore, a light source controller is installed at the annular light source.

[0015] Compared with the prior art, the utility model has the following advantages: by setting up an annular light source, the light spot area can cover the entire area to be detected of the fluorescence analyzer; the LED light sources in the annular light source are arranged in a circle at a certain angle, and can achieve a uniformity of more than 95% in the effective light spot area; the power of the annular light source ensures that the weak luminescent substances in the reagent card of the fluorescence analyzer can capture clear and recognizable images within a short exposure time, thereby improving the sensitivity and speed of detection. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.

[0017] Figure 1 It is a schematic diagram of an exploded view of an embodiment of the utility model;

[0018] Figure 2 This is a schematic diagram of the structure of the annular light source of the utility model;

[0019] Figure 3 This is a cross-sectional view of the annular light source of the utility model;

[0020] Figure 4 This is the front view of the annular light source of the utility model.

[0021] Reference numerals and component descriptions in the drawings:

[0022] 1. Base; 2. Reference bracket; 3. Adjustment platform; 4. Camera; 5. Ring light source; 51. Light source housing; 52. LED light source. DETAILED DESCRIPTION

[0023] The technical solution of the utility model will be clearly and completely described below through specific implementation methods. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of them. Based on the embodiments of the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.

[0024] See attached Figures 1 to 4 As shown, the present application is an optical detection device of a fluorescence analyzer, comprising a base 1 and a reference bracket 2 fixed on the base 1, the base 1 and the reference bracket 2 are used to ensure the verticality and coaxiality of the entire optical detection device and the area to be detected of the fluorescence analyzer, so that the captured image will not be distorted. The reference bracket 2 is arranged along the vertical direction, an adjustment platform 3 is installed at the upper position of the reference bracket 2, a camera 4 is installed on the adjustment platform 3, and an annular light source 5 is also installed on the reference bracket 2, the annular light source 5 is located below the camera 4, and the camera 4 and the annular light source 5 are arranged along the vertical direction of the reference bracket 2. The camera 4 in the present application is a high-definition fixed-focus industrial camera. By adjusting the adjustment platform 3, the distance between the camera 4 and the area to be detected of the fluorescence analyzer can be accurately adjusted in the vertical direction, thereby improving the imaging clarity of the camera 4. When the adjustment platform 3 adjusts the camera 4 to a suitable position, it is locked by a screw. In this way, the vertical distance between the camera 4 and the area to be detected of the fluorescence analyzer can be fine-tuned, and the central axes of the camera 4 and the area to be detected of the fluorescence analyzer will not be offset, so that the imaging will not be displaced, and a higher quality image can be obtained. After the entire optical path detection device is adjusted and locked, there are no moving parts, which increases the stability of the instrument.

[0025] Among them, the lens end of the camera 4 passes through the inner ring of the annular light source 5 and faces the area to be detected. The annular light source 5 includes a light source housing 51 and a plurality of LED light sources 52. The plurality of LED light sources 52 are tilted and arranged on the shell wall of the light source housing 51 facing the area to be detected. The plurality of LED light sources 52 are arranged along the circular track of the light source housing 51. The wavelength of the LED light source 52 is 365nm. The spot area of ​​the LED light source 52 covers the entire area to be detected. Each LED light source 52 is arranged in a circle at a certain angle, and can achieve a uniformity of more than 95% in the effective spot area. The power of the annular light source 5 ensures that the weak luminescent material in the reagent card of the fluorescence analyzer can be exposed in a short time to capture a clear and recognizable image, thereby improving the sensitivity and detection speed of the detection. Since the annular light source 5 is turned on for a long time, the heat generated is high, which affects the service life of the annular light source 5. By setting a light source controller to control the opening time, it is only turned on when the camera 4 is shooting, which greatly reduces the heat generated by the annular light source 5 and prolongs the service life of the annular light source 5.

[0026] Preferably, a light shield is installed on the reference bracket 2 in this embodiment, and the light shield is mounted on the annular light source 5. Since the 365nm wavelength light of the annular light source 5 is harmful to the human body to a certain extent, most of the light is enclosed in the instrument through the light shield and the instrument housing. Combined with the opening method of the annular light source 5, the damage of light to the human body is minimized.

[0027] Preferably, in this embodiment, cooling fans are installed on the side of the light shield and the rear side of the reference bracket 2, which greatly reduces the heat dissipated by the annular light source 5.

[0028] The above description of the disclosed embodiments enables professionals in the field to implement or use the utility model. Various modifications to these embodiments will be apparent to professionals in the field, and the general principles defined herein may be implemented in other embodiments without departing from the spirit or scope of the utility model. Therefore, the utility model will not be limited to the embodiments shown herein, but will conform to the widest range consistent with the principles and novel features disclosed herein.

Claims

1. An optical detection device for a fluorescence analyzer, characterized in that: It comprises a base and a reference bracket fixed on the base, a camera and an annular light source are installed on the reference bracket, the camera and the annular light source are both arranged along the vertical direction of the reference bracket, and the annular light source is located below the camera; the lens end of the camera passes through the inner ring of the annular light source and faces the area to be inspected; The annular light source comprises a light source housing and a plurality of LED light sources. The plurality of LED light sources are arranged at an angle on a shell wall of the light source housing facing the area to be detected, and the plurality of LED light sources are arranged along a circular track of the light source housing.

2. The optical detection device of a fluorescence analyzer according to claim 1, characterized in that: The lens end of the camera is coaxial with the area to be detected.

3. The optical detection device of a fluorescence analyzer according to claim 1, characterized in that: An adjustment platform is installed on the reference bracket, and the camera is installed on the adjustment platform.

4. The optical detection device of a fluorescence analyzer according to claim 1, characterized in that: A light shield is installed on the reference bracket, and the light shield is sleeved on the annular light source.

5. The optical detection device of a fluorescence analyzer according to claim 1, characterized in that: The light spot area of ​​the annular light source covers the area to be detected.

6. The optical detection device of a fluorescence analyzer according to claim 1, characterized in that: A heat dissipation fan is installed on the reference bracket.

7. The optical detection device of a fluorescence analyzer according to claim 1, characterized in that: A light source controller is installed at the annular light source.

Citation Information

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