Centrifugal machine roller for toad peptide extraction
By designing a multi-layer structure centrifuge roller, efficient multi-stage centrifugal separation of toad peptides is achieved, solving the problems of inefficiency and inconvenience in cleaning in the prior art.
Patent Information
- Application Number
- CN202421527573.5
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-07-01
- Publication Date
- 2025-04-25
- Estimated Expiration
- 2034-07-01
AI Technical Summary
The existing single-layer structure centrifuge rollers are inefficient during centrifugal separation of toad peptides, and the existing centrifugal filtration devices are inconvenient for cleaning.
A multi-layer structure centrifuge drum is designed, including a plurality of nested separation barrels arranged concentrically. By driving the rotating discs, the first centrifugal barrel, the second centrifugal barrel, the third centrifugal barrel and the filter barrel are realized simultaneously, and the installation and separation of the centrifugal barrel is facilitated by threaded connection of the fixed block.
Multi-stage separation of different precipitates of toad peptide and its mixture in single centrifugal separation is achieved, reducing the time required for multiple centrifugal separations and facilitating the cleaning of centrifugal barrels.
Smart Images

Figure CN222789462U_ABST
Abstract
Description
Technical Field
[0001] The utility model belongs to the technical field of toad peptide production equipment, and particularly relates to a centrifuge drum for toad peptide extraction. Background Art
[0002] Bufotoxin is a bioactive peptide typically derived from glandular secretions in the skin of toads. It possesses antibacterial and antiviral properties and is widely studied in the medical field for drug development and treatment.
[0003] During the production process of toad peptide, it is necessary to collect the glandular secretions of toad skin. Generally, the glandular secretions are stimulated by massaging the back of the toad skin, and the glandular secretions are dissolved in an acidic solution to extract the toad peptide. The acidic conditions help to break down proteins and make the toad peptide easier to dissolve. The extract is then centrifuged to precipitate the toad peptide.
[0004] During use, the existing centrifuge drums are mostly single-layer structures, which can only achieve a preliminary state for the centrifugal separation of toad peptides. Multiple subsequent centrifugal separations are required to extract the toad peptides, which is a waste of time. In addition, after use, the existing centrifugal filtration devices are mostly fixedly connected to the centrifuge barrel and the separation tank, making it inconvenient to remove the centrifuge barrel from the inside of the separation tank for cleaning. Utility Model Content
[0005] The technical problem to be solved by the utility model is that the existing centrifuge drum with a single separation barrel cannot meet the centrifugal separation requirements of toad peptides during the extraction of secretions from toads, and it is inconvenient to remove the internal centrifuge barrel of the existing centrifugal filtration device for cleaning after use.
[0006] To solve the above technical problems, the technical solution provided by the present utility model is as follows: A centrifuge drum for extracting toad peptides, including a separation tank. A bracket is provided at the bottom of the separation tank. A buckle cover is buckled on the top of the separation tank. The separation tank and the buckle cover are connected by multiple lock buckles. The bottom of the separation tank is an inclined slope. A discharge port is provided at one side of the bottom of the separation tank. A support plate is provided above the interior of the separation tank. A fixing frame is inserted on the support plate. A first centrifuge barrel is rotatably connected inside the fixing frame through a bearing. A drive motor is provided below the bracket at the bottom of the separation tank. The drive motor is connected with a rotating disc at the bottom of the separation tank. The bottom of the first centrifuge barrel is inserted into the rotating disc. A first support platform is provided above the interior of the first centrifuge barrel. A second centrifuge barrel is inserted into the bottom of the first support platform. A third centrifuge barrel is inserted inside the second centrifuge barrel through a second support platform. A filter barrel is inserted inside the third centrifuge barrel through a third support platform. A fixing block is screwed above the interior of the first support platform at the upper part of the second centrifuge barrel, the third centrifuge barrel and the filter barrel. A feed pipe is provided at the top of the buckle cover. A limiting plate which abuts against the upper part of the fixing frame is provided inside the buckle cover.
[0007] As an improvement, the slope matches the shape of the bottom of the separation tank. The discharge port is located at the lower end of the slope, and a valve is provided on the discharge port.
[0008] As an improvement, the support plate is an overall annular table surface, and multiple positioning holes are provided at the edge of the middle annular shape of the support plate. Corresponding multiple positioning columns are provided at the bottom of the fixing frame at the positions of the multiple positioning holes, and the multiple positioning columns and the multiple positioning holes are inserted and fixed.
[0009] As an improvement, the cross-section of the fixing frame is a "匚"-shaped annular structure.
[0010] As an improvement, the bearing is composed of an upper pressure plate, a lower pressure plate and a ball plate. Multiple rotatable balls are arranged in an annular array on the ball plate. The ball plate is located between the upper pressure plate and the lower pressure plate. Guide grooves matching the shape at the positions of the balls are provided inside the upper pressure plate and the lower pressure plate. The inner side of the ball plate is fixedly connected with the first centrifuge barrel.
[0011] As an improvement, the middle of the first support platform is an inverted cone structure. The edge of the second centrifuge barrel is erected on the first support platform. The edge of the third centrifuge barrel is erected on the second support platform. The edge of the filter barrel is erected on the third support platform. Multiple limiting grooves are provided inside the first support platform, the second support platform and the third support platform. Corresponding multiple limiting blocks are provided at the outer sides of the second centrifuge barrel, the third centrifuge barrel and the filter barrel at the positions of the multiple limiting grooves. [[ID=***16]]
[0012] As an improvement, the first centrifugal bucket, the second centrifugal bucket, the third centrifugal bucket and the filter bucket are concentrically arranged, and the diameters of the holes on the first centrifugal bucket, the second centrifugal bucket, the third centrifugal bucket and the filter bucket gradually increase from the outside to the inside.
[0013] As an improvement, the upper end surfaces of the second centrifugal bucket, the third centrifugal bucket and the filter bucket are located on the same plane, and rubber sealing gaskets are provided between the upper end surfaces of the second centrifugal bucket, the third centrifugal bucket and the filter bucket and the fixed block. The fixed block matches the shape of the inner side of the first support platform, and a discharge port matching the diameter of the filter bucket is provided between the fixed block and the rubber sealing gasket. The fixed block is located at the discharge port and has an inverted cone structure. A power assist ring is provided above the fixed block and on the outside of the discharge port.
[0014] As an improvement, a plurality of plug-in blocks are provided above the rotating disk, and corresponding plug-in slots are provided at the bottom of the first centrifugal bucket at the plurality of plug-in blocks.
[0015] The advantages of this utility model compared with the prior art are:
[0016] 1. The centrifuge drum is equipped with multiple nested separation barrels concentrically, which can separate different precipitates in toad peptides and their mixtures during a single centrifugation, thereby achieving the purpose of multi-stage separation in a single pass and reducing the time wasted by multiple centrifugations.
[0017] 2. The centrifuge drum is buckled with the inside of the separation tank through the bearing and the fixing frame on the outside of the first centrifugal bucket, and is plugged into the bottom of the first centrifugal bucket through the rotating disk at the bottom, ensuring the position of the first centrifugal bucket while providing power for the rotation of the first centrifugal bucket and the second centrifugal bucket, the third centrifugal bucket and the filter bucket inside. The threaded connection of the fixing block facilitates the installation and separation of the first centrifugal bucket, the second centrifugal bucket, the third centrifugal bucket and the filter bucket, thereby achieving the purpose of cleaning the centrifugal bucket. BRIEF DESCRIPTION OF THE DRAWINGS
[0018] Figure 1 This is a structural diagram of a centrifuge drum for extracting toad peptides in the utility model.
[0019] Figure 2 This is a cross-sectional three-dimensional structural diagram of a centrifuge drum for extracting toad peptides according to the present invention.
[0020] Figure 3 This is a diagram of the internal explosion structure of the first separation barrel of a centrifuge drum for extracting toad peptides in the utility model.
[0021] Figure 4 This is a structural diagram of the connection between the first separation barrel and the rotating disk of a centrifuge drum for extracting toad peptides according to the utility model.
[0022] Figure 5 This is an exploded structural diagram of the fixed frame of the centrifuge drum for extracting toad peptides in the utility model.
[0023] As shown in the figure: 1. Separation tank; 2. Bracket; 3. Buckle cover; 4. Multiple locks; 5. Slope; 6. Discharge port; 7. Support plate; 8. Fixed frame; 9. Bearing; 10. First centrifugal bucket; 11. Driving motor; 12. Rotating disk; 13. First support platform; 14. Second centrifugal bucket; 15. Second support platform; 16. Third centrifugal bucket; 17. Third support platform; 18. Filter bucket; 19. Fixed block; 20. Limit plate; 21. Valve; 22. Multiple positioning holes; 23. Multiple positioning columns; 24. Upper pressure plate; 25. Lower pressure plate; 26. Ball plate; 27. Ball; 28. Guide groove; 29. Multiple limiting grooves; 30. Multiple limiting blocks; 31. Rubber sealing gasket; 32. Discharge port; 33. Power ring; 34. Multiple plug-in blocks; 35. Plug-in groove; 36. Feed pipe DETAILED DESCRIPTION
[0024] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technicians in this field without making creative efforts are within the scope of protection of the present invention.
[0025] In the description of the utility model, it should be noted that, unless otherwise expressly specified or limited, the terms "installed," "provided with," "connected," etc. should be understood in a broad sense. For example, "connected" can mean a fixed connection, a detachable connection, or an integral connection; it can be a mechanical connection or an electrical connection; it can be a direct connection or an indirect connection through an intermediate medium, or it can be internal communication between two components. Those skilled in the art will understand the specific meanings of the above terms in this utility model based on the specific circumstances.
[0026] Example 1:
[0027] As the instruction manual Figure 1-2As shown, a centrifuge drum for extracting toad peptides comprises a separation tank 1, a bracket 2 is provided at the bottom of the separation tank 1, a buckle cover 3 is buckled on the top of the separation tank 1, the separation tank 1 and the buckle cover 3 are buckled and connected by multiple lock buckles 4, the bottom of the separation tank 1 is an inclined slope 5, a discharge port 6 is provided on one side of the bottom of the separation tank 1, the slope 5 matches the shape of the bottom of the separation tank 1, the discharge port 6 is located at the lower end of the slope 5, and a valve 21 is provided on the discharge port 6, a support plate 7 is provided on the upper part of the interior of the separation tank 1, and a fixing frame 8 is plugged into the support plate 7. The support plate 7 is an annular table as a whole, and a plurality of positioning holes 22 are provided at the annular edge in the middle of the support plate 7. The bottom of the fixing frame 8 is located at the plurality of positioning holes 22 and is provided with a corresponding plurality of positioning columns 23, and the plurality of positioning columns 23 and the plurality of positioning holes 22 are plugged and fixed. The interior of the fixing frame 8 is rotatably connected to the first centrifugal bucket 10 through the bearing 9. The bottom of the separation tank 1 is located below the bracket 2 and is provided with a drive motor 11. The drive motor 11 is located at the bottom of the separation tank 1 and is connected to a rotating disk 12. The bottom of the first centrifugal bucket 10 is plugged into the rotating disk 12.
[0028] Correspondingly, a feed pipe 36 is provided on the top of the buckle cover 3 , and a limit plate 20 is provided on the inner side of the buckle cover 3 to abut against the upper side of the fixing frame 8 .
[0029] As the instruction manual Figure 2-3 As shown, a first support platform 13 is provided above the interior of the first centrifugal bucket 10, a second centrifugal bucket 14 is plugged into the bottom of the first support platform 13, a third centrifugal bucket 16 is plugged into the inner side of the second centrifugal bucket 14 through a second support platform 15, a filter bucket 18 is plugged into the inner side of the third centrifugal bucket 16 through a third support platform 17, and a fixing block 19 is threadedly connected to the inner side of the first support platform 13 above the second centrifugal bucket 14, the third centrifugal bucket 16 and the filter bucket 18.
[0030] Correspondingly, the middle of the first support platform 13 is an inverted cone structure, the edge of the second centrifugal bucket 14 is mounted on the first support platform 13, the edge of the third centrifugal bucket 16 is mounted on the second support platform 15, and the edge of the filter bucket 18 is mounted on the third support platform 17. The inner sides of the first support platform 13, the second support platform 15 and the third support platform 17 are all provided with multiple limiting grooves 29, and the outer sides of the second centrifugal bucket 14, the third centrifugal bucket 16 and the filter bucket 18 are located at the multiple limiting grooves 29 and are provided with corresponding multiple limiting blocks 30.
[0031] Accordingly, the first centrifugal bucket 10, the second centrifugal bucket 14, the third centrifugal bucket 16 and the filter bucket 18 are concentrically arranged, and the diameters of the holes therein gradually increase from the outside to the inside.
[0032] Correspondingly, the upper end surfaces of the second centrifugal barrel 14, the third centrifugal barrel 16 and the filter barrel 18 are located on the same plane, and a rubber gasket 31 is provided between the upper end surfaces of the second centrifugal barrel 14, the third centrifugal barrel 16 and the filter barrel 18 and the fixing block 19. The fixing block 19 is matched with the shape inside the first support platform 13. A material discharging port 32 matching the diameter of the filter barrel 18 is provided between the fixing block 19 and the rubber gasket 31. The fixing block 19 is of an inverted conical structure at the material discharging port 32, and a boosting ring 33 is provided outside the material discharging port 32 above the fixing block 19.
[0033] As shown in the attached Figure 4 specification, as shown in the figure, a plurality of plug-in blocks 34 are provided above the rotating disk 12, and corresponding plug-in grooves 35 are provided at the bottom of the first centrifugal barrel 10 at the positions of the plurality of plug-in blocks 34 for plugging when the first centrifugal barrel 10 is placed on the rotating disk 12, so that the rotating disk 12 drives the first centrifugal barrel 10 to rotate.
[0034] As shown in the attached Figure 5 specification, as shown in the figure, the cross section of the fixing frame 8 is a "C"-shaped annular structure. The bearing 9 is composed of an upper pressing plate 24, a lower pressing plate 25 and a ball plate 26. A plurality of rotatably connected spheres 27 are arranged in an annular array on the ball plate 26. The ball plate 26 is located between the upper pressing plate 24 and the lower pressing plate 25, and guide grooves 28 matching the shape at the positions of the spheres 27 are provided inside the upper pressing plate 24 and the lower pressing plate 25. The inner side of the ball plate 26 is fixedly connected to the first centrifugal barrel 10.
[0035] During the specific implementation of the present invention, the mixture of toad peptide and acidic solution is directly fed into the filter barrel 18 through the feed pipe through the discharge port 32 on the fixed block 19, and the impurities in the mixture are filtered by the filter barrel 18. The filtered mixture drips into the interior of the third centrifugal barrel 16 on the outside, and the rotating disk 12 is driven to rotate by the driving motor 11, and then the first centrifugal barrel 10 is driven to rotate by the multiple plug-in blocks 34 on the rotating disk 12 and the plug-in grooves 35 at the bottom of the first centrifugal barrel 10. During the rotation of the first centrifugal barrel 10, the second centrifugal barrel 14, the third centrifugal barrel 16 and the filter barrel 18 fixed by the first support platform 13, the second support platform 15 and the third support platform 17 all rotate synchronously, and the upper part of the fixed frame 8 is fixed by the limiting plate 20 under the buckle cover 3, and the multiple positioning columns 23 at the bottom of the fixed frame 8 and the support The multiple positioning holes 22 on the support plate 7 are plugged in to ensure that the position of the fixing frame 8 is fixed, so that the first centrifugal bucket 10 rotates at high speed between the upper pressure plate 24 and the lower pressure plate 25 inside the fixing frame 8 with the ball plate 26. The toad peptide centrifugally separated from the third centrifugal bucket 16 is gradually separated into the second centrifugal bucket 14, the first centrifugal bucket 10 and the separation tank 1 as the holes shrink, and moves from the inner wall of the separation tank 1 to the slope 5, and is discharged from the discharge port 6 as the slope 5 is tilted; after the separation is completed, the buckle cover 3 is opened through the multiple lock buckles 4, and the fixing frame 8 is picked up to take out the connected first centrifugal bucket 10, and the fixing block 19 is removed from the first support platform 13 in the first centrifugal bucket 10 through the assistant ring on the fixing block 19, so that the second centrifugal bucket 14, the third centrifugal bucket 16 and the filter bucket 18 fixed inside can be taken out for cleaning, which is convenient and quick.
[0036] The above description of the present invention and its embodiments is non-limiting. The specific embodiments shown in the specific embodiments are only one embodiment of the present invention, and the actual structure is not limited thereto. In short, if a person skilled in the art is inspired by the above, and does not deviate from the purpose of the present invention, without creatively designing a structure and embodiment similar to the technical solution, they shall fall within the scope of protection of the present invention.
Claims
1. A centrifuge drum for extracting toad peptides, comprising a separation tank, a bracket is provided at the bottom of the separation tank, a buckle cover is buckled on the top of the separation tank, and the separation tank and the buckle cover are buckled and connected by a plurality of lock buckles, characterized in that: The bottom of the separation tank is an inclined slope. A discharge port is arranged on one side of the bottom of the separation tank. A support plate is arranged above the interior of the separation tank. A fixing frame is inserted on the support plate. A first centrifugal barrel is rotatably connected to the interior of the fixing frame through a bearing. A driving motor is arranged below the support of the bottom of the separation tank. The driving motor is connected with a rotating disc at the bottom of the separation tank. The bottom of the first centrifugal barrel is inserted into the rotating disc. A first support platform is arranged above the interior of the first centrifugal barrel. A second centrifugal barrel is inserted into the bottom of the first support platform. A third centrifugal barrel is inserted into the inner side of the second centrifugal barrel through a second support platform. A filter barrel is inserted into the inner side of the third centrifugal barrel through a third support platform. A fixing block is connected by thread to the inner side of the first support platform above the second centrifugal barrel, the third centrifugal barrel and the filter barrel. A feed pipe is arranged at the top of the cover. A limiting plate which abuts against the upper part of the fixing frame is arranged on the inner side of the cover.
2. The centrifuge drum for extracting toad peptides according to claim 1, characterized in that: The slope matches the shape of the bottom of the separation tank. The discharge port is located at the lower end of the slope, and a valve is arranged on the discharge port.
3. The centrifuge drum for extracting toad peptides according to claim 1, characterized in that: The support plate is an overall annular tabletop, and a plurality of positioning holes are arranged at the edge of the middle annular part of the support plate. A plurality of corresponding positioning columns are arranged at the positions of the plurality of positioning holes at the bottom of the fixing frame, and the plurality of positioning columns are inserted and fixed with the plurality of positioning holes.
4. The centrifuge drum for extracting toad peptides according to claim 1, characterized in that: The cross section of the fixing frame is a "C"-shaped annular structure.
5. The centrifuge drum for extracting toad peptides according to claim 1, characterized in that: The bearing is composed of an upper pressure plate, a lower pressure plate and a ball plate. A plurality of rotatably connected balls are arranged in an annular array on the ball plate. The ball plate is located between the upper pressure plate and the lower pressure plate, and guide grooves which match the shape at the positions of the balls are arranged on the inner sides of the upper pressure plate and the lower pressure plate. The inner side of the ball plate is fixedly connected with the first centrifugal barrel.
6. The centrifuge drum for extracting toad peptides according to claim 1, characterized in that: The middle of the first support platform is an inverted cone structure. The edge of the second centrifugal barrel is erected on the first support platform. The edge of the third centrifugal barrel is erected on the second support platform. The edge of the filter barrel is erected on the third support platform. A plurality of limiting grooves are arranged on the inner sides of the first support platform, the second support platform and the third support platform. A plurality of corresponding limiting blocks are arranged at the positions of the plurality of limiting grooves on the outer sides of the second centrifugal barrel, the third centrifugal barrel and the filter barrel.
7. The centrifuge drum for extracting toad peptides according to claim 1, characterized in that: The first centrifugal barrel, the second centrifugal barrel, the third centrifugal barrel and the filter barrel are concentrically arranged, and the diameters of the holes on the first centrifugal barrel, the second centrifugal barrel, the third centrifugal barrel and the filter barrel gradually increase from outside to inside.
8. The centrifuge drum for extracting toad peptides according to claim 1, characterized in that: The upper end surfaces of the second centrifugal barrel, the third centrifugal barrel and the filter barrel are on the same plane. A rubber gasket is arranged between the upper end surfaces of the second centrifugal barrel, the third centrifugal barrel and the filter barrel and the fixing block. The fixing block matches the shape of the inner side of the first support platform. A blanking port which matches the diameter of the filter barrel is arranged in the middle of the fixing block and the rubber gasket. The fixing block is of an inverted cone structure at the blanking port. A boosting ring is arranged outside the blanking port above the fixing block.
9. The centrifuge drum for extracting toad peptides according to claim 1, characterized in that: A plurality of insertion blocks are arranged above the rotating disc. A plurality of corresponding insertion grooves are arranged at the positions of the plurality of insertion blocks at the bottom of the first centrifugal barrel.