Biological filtration anti-pollution separation device

Abstract

The utility model discloses a biological filtration anti-pollution separation device which comprises a filtration component and a deep hole plate, the deep hole plate is arranged above the filtering part; and the deep hole plate can be assembled with the filtering part to form a closed filtering space. The biological filtration anti-pollution separation device is simple in overall structural design, so that the biological filtration anti-pollution separation device is more convenient to install, use and maintain, and the operation difficulty is reduced; meanwhile, the design of double-layer filter cotton is adopted in the device, so that the filtering effect is improved, most impurities and particles are removed in the filtering process of the sample, and a purer sample is obtained; and finally, the design of the double-layer filter cotton can prevent waste liquid from flowing back, so that secondary pollution of the waste liquid to the sample is avoided, and the quality and purity of the sample are ensured to the greatest extent.

Description

Technical Field

[0001] The utility model belongs to the technical field of cell supernatant filtration, and particularly relates to a biological filtration anti-pollution separation device. Background Art

[0002] During the process of cell culture, experimental non-essential substances such as cell debris and impurities will be generated, and the clarification of cell supernatant is the first step in downstream purification of biopharmaceutical processes.

[0003] In order to obtain clarified cell supernatant, a centrifuge is usually used at present. Through the action of centrifugal force, cells, cell debris and other impurities are separated into precipitates, and the supernatant is removed to achieve the purpose of obtaining clarified supernatant. However, the traditional separation device is lacking in ensuring the filtration effect and preventing the backflow of waste liquid. The traditional separation device generally uses a simple valve to control the discharge of waste liquid, but these valves may have problems with poor sealing and are prone to waste liquid backflow. Summary of the Utility Model

[0004] Purpose of the utility model: In order to overcome the above deficiencies, the purpose of the utility model is to provide a biological filtration anti-pollution separation device, the overall structure of which is designed simply, making it more convenient in the installation, use and maintenance processes, reducing the operation difficulty; at the same time, a double-layer filter cotton design is adopted inside, improving the filtration effect, ensuring that most of the impurities and particles are removed from the sample during the filtration process, and obtaining a purer sample; finally, the double-layer filter cotton design can prevent the backflow of waste liquid, avoiding the secondary pollution of the sample caused by the waste liquid, and ensuring the quality and purity of the sample to the greatest extent.

[0005] Technical solution: In order to achieve the above purpose, the utility model provides a biological filtration anti-pollution separation device, which includes a filtration component and a deep well plate; the deep well plate is arranged above the filtration component; the deep well plate can be assembled with the filtration component to form a closed filtration space.

[0006] Further, the filtration component includes a filtration inner core and a housing; the filtration inner core is arranged inside the housing. The filtration inner core is used to complete the separation of removing the supernatant.

[0007] Further, the filtration inner core includes a first filter cotton, an inner frame and a second filter cotton; the first filter cotton is arranged above the inner frame; the second filter cotton is arranged below the inner frame. The double-layer filter cotton prevents the backflow of waste liquid and ensures the sample quality.

[0008] Furthermore, the inner frame includes a main frame and a soft rubber ring; the main frame is made of hard rubber and is provided with a number of hollow grids inside; a circular protrusion is provided on the peripheral surface of the upper part of the main frame, and a number of buckles are provided on the upper side of the four peripheral edges; the buckles are used to cooperate with the outer shell for fixation; the soft rubber ring is arranged on the peripheral surface of the main frame and outside the buckles, and is assembled in cooperation with the protrusion on the peripheral surface of the main frame. Both the main frame and the soft rubber ring are designed with flexible material frames, which facilitate the disassembly and assembly of the filtering space.

[0009] Furthermore, a number of support columns are provided at the lower part of the main frame to ensure that the inner frame can be stably placed in the outer shell.

[0010] Furthermore, the lower ends of the protrusions on the peripheral surface of the main frame are flush with the lower ends of the soft rubber ring, and the two cooperate with each other to ensure the filtering quality.

[0011] Furthermore, a number of limiting protrusions are provided on the upper part of the inner side wall of the outer shell, and the limiting protrusions cooperate with the buckles provided on the main frame to complete the assembly. The cooperation setting of a number of buckles and limiting protrusions prevents the inner frame from falling off and ensures the stability of the inner frame.

[0012] Furthermore, a number of limiting platforms are provided on the lower part of the inner side wall of the outer shell, and the limiting platforms cooperate with the soft rubber ring and the lower ends of the protrusions on the peripheral surface of the main frame to complete the sealing assembly. The cooperation of the limiting platforms with the soft rubber ring and the lower ends of the protrusions on the peripheral surface of the main frame ensures the tightness of the filtering space.

[0013] Furthermore, a number of limiting plates are provided at the bottom of the outer shell. The limiting plates limit the second filter cotton to prevent the second filter cotton from being too loose and affecting the filtering effect.

[0014] From the above technical solutions, it can be seen that the present utility model has the following beneficial effects:

[0015] The purpose of the present utility model is to provide a biological filtration anti-pollution separation device, the overall structure design of which is simple, making it more convenient in the installation, use and maintenance processes, reducing the operation difficulty; at the same time, a double-layer filter cotton design is adopted inside, improving the filtering effect, ensuring that most of the impurities and particles are removed from the sample during the filtering process, and obtaining a purer sample; finally, the double-layer filter cotton design can prevent the waste liquid from flowing back, avoiding the secondary pollution of the waste liquid to the sample, and ensuring the quality and purity of the sample to the greatest extent. BRIEF DESCRIPTION OF THE DRAWINGS

[0016] Figure 1 is a structural schematic diagram of a biological filtration anti-pollution separation device described in the present utility model;

[0017] Figure 2 is a framework schematic diagram of a biological filtration anti-pollution separation device described in the present utility model;

[0018] Figure 3 Partial enlarged schematic view of the limit protrusion of a biological filtration anti-pollution separation device according to the present utility model;

[0019] Figure 4 Partial enlarged schematic view of the limit platform of a biological filtration anti-pollution separation device according to the present utility model;

[0020] Figure 5 Partial enlarged schematic view of the limit plate of a biological filtration anti-pollution separation device according to the present utility model;

[0021] In the figure:

[0022] 1 - Filter component; 11 - Inner filter core; 12 - Outer shell; 111 - First filter cotton; 112 - Inner frame; 113 - Second filter cotton; 1121 - Main frame; 1122 - Soft rubber ring;

[0023] 2 - Deep hole plate. Specific implementation manner

[0024] The embodiments of the present utility model will be described in detail below. The examples of the embodiments are shown in the accompanying drawings, where the same or similar reference numerals represent the same or similar elements or elements with the same or similar functions from beginning to end. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to explain the present utility model and should not be construed as a limitation to the present utility model.

[0025] Embodiment 1

[0026] In this embodiment, as Figure 1 , the present utility model discloses a biological filtration anti-pollution separation device, including: a filter component 1 and a deep hole plate 2; the deep hole plate 2 is arranged above the filter component 1; the deep hole plate 2 can be assembled with the filter component 1 to form a closed filtration space. The filter component 1 is a housing assembly with a filtration function.

[0027] Embodiment 2

[0028] On the basis of Embodiment 1, in this embodiment, as Figure 1 and Figure 2 , the present utility model discloses a biological filtration anti-pollution separation device, the filter component 1 includes a filter inner core 11 and an outer shell 12; the filter inner core 11 is arranged inside the outer shell 12. The outer shell 12 plays a protective role, and the filter inner core 11 is used to complete the filtration operation.

[0029] In this embodiment, as Figure 1 and Figure 2, the filter inner core 11 includes a first filter cotton 111, an inner frame 112 and a second filter cotton 113; the first filter cotton 111 is arranged above the inner frame 112; the second filter cotton 113 is arranged below the inner frame 112. The first filter cotton 111, the inner frame 112 and the second filter cotton 113 are stacked in sequence to form the filter inner core 11, ensuring the filtering effect and preventing the backflow of waste liquid.

[0030] In this embodiment, as Figure 1 and Figure 2 , the inner frame 112 includes a main frame 1121 and a soft rubber ring 1122; the main frame 1121 is made of hard rubber and is provided with a plurality of hollow grids therein; a circle of protrusions is provided on the upper peripheral surface of the main frame 1121, and a plurality of buckles are provided on the upper side of the four peripheral edges; the buckles are used for cooperating with the outer shell 12 for fixing; the soft rubber ring 1122 is arranged on the peripheral surface of the main frame 1121 and outside the buckles, and is assembled in cooperation with the protrusions on the peripheral surface of the main frame 1121. Both the main frame 1121 and the soft rubber ring 1122 are designed with flexible material frames, facilitating the disassembly and assembly of the filtering space.

[0031] In this embodiment, as Figure 2 , a plurality of support columns are provided at the lower part of the main frame 1121 to ensure that the inner frame can be stably placed in the outer shell 12.

[0032] In this embodiment, as Figure 4 , the lower end of the protrusion on the peripheral surface of the main frame 1121 is flush with the lower end of the soft rubber ring 1122.

[0033] In this embodiment, as Figure 3 , a plurality of limit protrusions are provided on the upper part of the inner side wall of the outer shell 12, and the limit protrusions cooperate with the buckles provided on the main frame 1121 to complete the assembly, preventing the inner frame from falling off and ensuring the stability of the inner frame.

[0034] In this embodiment, as Figure 4 , a plurality of limit platforms are provided on the lower part of the inner side wall of the outer shell 12, and the limit platforms cooperate with the soft rubber ring 1122 and the lower end of the protrusion on the peripheral surface of the main frame 1121 to complete the sealing assembly, ensuring the sealing of the filtering space.

[0035] In this embodiment, as Figure 5 , a plurality of limit plates are provided at the bottom of the outer shell 12. The limit plates limit the second filter cotton 113 to prevent the second filter cotton 113 from being too loose and affecting the filtering effect.

[0036] The working principle of the above embodiment is:

[0037] The utility model discloses a biological filtration anti-pollution separation device. First, the first filter cotton 111, the inner frame 112, and the second filter cotton 113 are stacked in sequence and placed inside the outer shell 12. Sealed assembly is completed through the cooperation of several limiting protrusions on the upper part of the inner side wall of the outer shell 12 with the buckles provided on the main frame 1121, several limiting platforms on the lower part of the inner side wall of the outer shell 12 with the soft rubber ring 1122, and the lower end of the protrusion on the circumferential surface of the main frame 1121. Then, the liquid to be detected is added to the deep well plate 2. Next, the deep well plate 2 is assembled with the filtering component 1 to form a closed filtering space. Finally, the assembled product is placed in a centrifugal device, and the liquid is filtered and separated by centrifugal force to obtain the required sample.

[0038] The above are only the preferred embodiments of the utility model. It should be noted that for those of ordinary skill in the art in this technical field, several improvements can be made without departing from the principle of the utility model, and these improvements should also be regarded as the protection scope of the utility model.

Claims

1. A biological filtration anti-pollution separation device, characterized in that: include: A filter component (1) and a deep hole plate (2), wherein the deep hole plate (2) is arranged above the filter component (1); the deep hole plate (2) can be assembled with the filter component (1) to form a closed filter space.

2. The biofiltration anti-pollution separation device according to claim 1, characterized in that: The filter component (1) comprises a filter inner core (11) and an outer shell (12), wherein the filter inner core (11) is arranged inside the outer shell (12).

3. The biofiltration anti-pollution separation device according to claim 2, characterized in that: The filter inner core (11) comprises a first filter cotton (111), an inner frame (112) and a second filter cotton (113); The first filter cotton (111) is arranged above the inner frame (112); and the second filter cotton (113) is arranged below the inner frame (112).

4. The biofiltration anti-pollution separation device according to claim 3, characterized in that: The inner frame (112) comprises a main frame (1121) and a soft rubber ring (1122); The main frame (1121) is made of hard rubber and is provided with a plurality of hollow grids therein; a circle of protrusions is provided on the upper circumference of the main frame (1121), and a plurality of buckles are provided on the upper sides of the surrounding edges; the buckles are used to cooperate and fix with the outer shell (12); the soft rubber ring (1122) is provided on the circumference of the main frame (1121) and on the outside of the buckles, and is assembled with the protrusions on the circumference of the main frame (1121).

5. The biofiltration anti-pollution separation device according to claim 4, characterized in that: A plurality of support columns are provided at the lower part of the main frame (1121).

6. The biofiltration anti-pollution separation device according to claim 4, characterized in that: The lower end of the protrusion on the peripheral surface of the main frame (1121) is flush with the lower end of the soft rubber ring (1122).

7. The biofiltration anti-pollution separation device according to claim 4, characterized in that: A plurality of limiting protrusions are provided on the upper portion of the inner side wall of the housing (12), and the limiting protrusions cooperate with snap-fits provided on the main frame (1121) to complete assembly.

8. The biofiltration anti-pollution separation device according to claim 6, characterized in that: A plurality of limit platforms are provided at the lower portion of the inner side wall of the housing (12), and the limit platforms cooperate with the soft rubber ring (1122) and the lower end of the convex surface of the main frame (1121) to complete the sealing assembly.

9. The biofiltration anti-pollution separation device according to claim 2, characterized in that: A plurality of limiting plates are provided at the bottom of the housing (12).

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