Titration device for drug inspection

Abstract

The utility model relates to the technical field of medicine inspection equipment, in particular to a titration device for medicine inspection. According to the technical scheme, the burette comprises a support and further comprises a burette movably installed on the support, the bottom of the burette is connected with a titration bottom head, and the end, connected with the burette, of the titration bottom head is connected with a rotary piston; and the rotary piston is provided with a connecting mechanism for preventing liquid pollution during inspection of different medicines after the connecting end of the burette and the titration bottom head is quickly disassembled and assembled. Through the cooperation of structures such as the burette, the titration bottom head, the rotary piston, the connecting mechanism and the reset mechanism, a new rotary piston can be quickly replaced after a detected medicine is replaced, and the replaced new rotary piston not only can ensure that different medicines cannot be subjected to cross contamination, avoids impurity residues influencing an experiment result, but also can be used for quickly replacing the new rotary piston. The deviation caused by the influence of residual substances in the last experiment can be avoided, and the data accuracy and reliability of each experiment are ensured.

Description

Technical Field

[0001] The utility model relates to the technical field of pharmaceutical inspection equipment, in particular to a titration device for pharmaceutical inspection. Background Art

[0002] Titration is a commonly used analytical chemistry technique that can be used to accurately determine the content of a certain component in a drug. Through titration, according to the chemical equation of the reaction and the change of the end-point indicator, the concentration of the target component in the drug can be accurately calculated. Titration is a widely accepted standardized analytical method with high precision and reliability, and is applicable to various types of drug component analysis and inspection. The titration device used for drug inspection is provided with a burette, and the burette is provided with a rotary piston, which can adjust the size of the orifice at the bottom of the burette by rotation, so as to control the flow rate of the liquid. In addition, the burette is usually made of glass or plastic, with a relatively simple structure and no excessive hidden parts, which is convenient for cleaning.

[0003] However, the rotary piston structure on some burettes is complex. After cleaning, the drug inspection liquid used last time will remain in the rotary piston, and when reacting with the newly added reagent during the next use, it will cause deviation in the experimental results. And replacing the entire burette requires a certain amount of time to recalibrate and adapt, and the experiment cannot be resumed quickly to maintain the continuity of the experiment. Content of the Utility Model

[0004] The purpose of the utility model is to solve the problem that the rotary piston structure on some burettes is complex, the drug inspection liquid used last time will remain in the rotary piston after cleaning, and when reacting with the newly added reagent during the next use, it will cause deviation in the experimental results. And replacing the entire burette requires a certain amount of time to recalibrate and adapt, and the experiment cannot be resumed quickly to maintain the continuity of the experiment, and a titration device for pharmaceutical inspection is proposed.

[0005] The technical solution of the utility model: A titration device for pharmaceutical inspection, including a bracket, further including: a burette movably installed on the bracket, a titration bottom head connected to the bottom of the burette, a rotary piston connected to the connection end of the titration bottom head and the burette, and a connection mechanism provided on the rotary piston to prevent liquid contamination during different drug inspections after the quick disassembly and assembly of the connection end of the burette and the titration bottom head; a reset mechanism provided on the burette and the titration bottom head to keep the distance between the burette and the titration bottom head unchanged before and after replacing the rotary piston.

[0006] Optionally, the connecting mechanism includes a connecting top pipe and a connecting bottom pipe fixedly connected above and below the rotary piston. The top end of the connecting top pipe is fixedly sleeved with a sealed connecting top sleeve. One end of the sealed connecting top sleeve away from the connecting top pipe is movably sleeved with the bottom end of the burette. The bottom end of the connecting bottom pipe is fixedly sleeved with a sealed connecting bottom sleeve. One end of the sealed connecting bottom sleeve away from the connecting bottom pipe is movably sleeved with the top end of the burette bottom head.

[0007] Optionally, the reset mechanism includes a first support frame and a second support frame. The first support frame is fixedly sleeved with the bottom end of the burette. The second support frame is fixedly sleeved with the top end of the burette bottom head. The opposite surfaces of the first support frame and the second support frame are fixedly connected with upper and lower corresponding first telescopic insertion rods and second telescopic insertion rods. The proximal ends of the first telescopic insertion rod and the second telescopic insertion rod are sleeved with a main sleeve rod. A reset spring is arranged inside the main sleeve rod. The two ends of the reset spring are fixedly connected with the opposite ends of the first telescopic insertion rod and the second telescopic insertion rod.

[0008] Optionally, a pair of snap rings for clamping the first telescopic insertion rod and the second telescopic insertion rod to insert into the main sleeve rod are fixedly connected inside the main sleeve rod.

[0009] Optionally, the reset mechanism is used to prevent the rotary piston, the bottom end of the burette, and the top end of the burette bottom head from falling off.

[0010] Optionally, a perforation for the reset spring to pass through movably is formed in the middle of the snap ring.

[0011] Optionally, one end of the sealed connecting top sleeve connected to the bottom end of the burette can expand or contract according to the caliber of the bottom end of the burette, and one end of the sealed connecting bottom sleeve connected to the burette bottom head can expand or contract according to the caliber of the top end of the burette bottom head. The materials of the sealed connecting top sleeve and the sealed connecting bottom sleeve are both rubber.

[0012] Compared with the prior art, the utility model has the following beneficial technical effects:

[0013] The utility model utilizes the cooperation of structures such as a burette, a burette bottom head, a rotary piston, a connecting mechanism, and a reset mechanism. After replacing the medicine to be tested, a new rotary piston can be quickly replaced. Replacing the new rotary piston can not only ensure that there is no cross-contamination between different medicines and avoid the residual impurities that affect the experimental results. Further, it can also avoid the deviation caused by the influence of the residual substances from the previous experiment, ensuring the data accuracy and reliability of each experiment. BRIEF DESCRIPTION OF THE DRAWINGS

[0014] Figure 1 A structural schematic diagram of a titration device for medicine inspection according to the utility model is given;

[0015] Figure 2 It is Figure 1 an enlarged schematic view of part A in

[0016] Figure 3 It is Figure 2 a schematic view of a partially disassembled structure in

[0017] Figure 4 It is Figure 2 a schematic cross-sectional structure view of the main sleeve rod in

[0018] Reference numerals: 1, support; 2, burette; 21, first support frame; 22, first telescopic insertion rod; 3, burette bottom head; 31, second support frame; 32, second telescopic insertion rod; 4, rotary piston; 41, connecting top pipe; 42, sealed connecting top sleeve; 43, connecting bottom pipe; 44, sealed connecting bottom sleeve; 5, main sleeve rod; 51, snap ring; 52, return spring. Detailed implementation manners

[0019] Next, the technical solutions of the present invention will be clearly and completely described in conjunction with the accompanying drawings. Obviously, the described embodiments are some, but not all, of the embodiments of the present invention.

[0020] Generally, the components of the embodiments of the present invention described and shown in the drawings here can be arranged and designed in various different configurations. Therefore, the following detailed description of the embodiments of the present invention provided in the drawings is not intended to limit the scope of the claimed present invention, but merely represents the selected embodiments of the present invention.

[0021] All other embodiments obtained by those of ordinary skill in the art based on the embodiments of the present invention without creative efforts shall fall within the scope of protection of the present invention.

[0022] In the description of the present invention, it should be noted that the orientation or positional relationship indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. is based on the orientation or positional relationship shown in the drawings, and is only for the convenience of describing the present invention and simplifying the description, rather than indicating or implying that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of the present invention. In addition, the terms "first", "second", "third" are only used for descriptive purposes and cannot be construed as indicating or implying relative importance.

[0023] It should be noted that the term "including", "comprising" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device including a series of elements not only includes those elements, but also includes other elements not expressly listed, or elements inherent to such process, method, article or device. In this specification, the schematic representation of the above terms does not necessarily refer to the same embodiment or example. Moreover, the specific features, structures, materials or characteristics described may be combined in any one or more embodiments or examples in a suitable manner.

[0024] In the description of the present utility model, it should be noted that, unless otherwise clearly specified and defined, the terms "installed", "connected" and "coupled" should be understood in a broad sense. For example, it may be a fixed connection, a detachable connection or an integral connection; it may be a mechanical connection or an electrical connection; it may be directly connected or indirectly connected through an intermediate medium, and it may be the communication inside two elements. For those of ordinary skill in the art, the specific meanings of the above terms in the present utility model can be understood according to specific circumstances.

[0025] Embodiment

[0026] As Figures 1-4 shown, a titration device for drug inspection proposed by the present utility model includes a bracket 1, and further includes: a burette 2 movably installed on the bracket 1, a titration bottom head 3 connected to the bottom of the burette 2, a rotary piston 4 connected to the connection end of the titration bottom head 3 and the burette 2, and a connection mechanism provided on the rotary piston 4 to avoid liquid contamination during different drug inspections after the quick disassembly and assembly of the connection end of the burette 2 and the titration bottom head 3; a reset mechanism provided on the burette 2 and the titration bottom head 3 to keep the distance between the burette 2 and the titration bottom head 3 unchanged before and after replacing the rotary piston 4, and the reset mechanism is used to prevent the rotary piston 4 from falling off the bottom end of the burette 2 and the top end of the titration bottom head 3.

[0027] Further, the connection mechanism includes a connection top pipe 41 and a connection bottom pipe 43 fixedly connected above and below the rotary piston 4, and the connection top pipe 41 and the connection bottom pipe 43 are made of glass tubes. A sealing connection top sleeve 42 is fixedly sleeved on the top end of the connection top pipe 41, and one end of the sealing connection top sleeve 42 away from the connection top pipe 41 is movably sleeved on the bottom end of the burette 2. A sealing connection bottom sleeve 44 is fixedly sleeved on the bottom end of the connection bottom pipe 43, and the sealing connection top sleeve 42 and the sealing connection bottom sleeve 44 are made of rubber, and their functions are to make the connection between the connection top pipe 41 and the burette 2 tight to avoid liquid leakage. At the same time, the connection between the connection bottom pipe 43 and the titration bottom head 3 is also made tight to avoid liquid leakage. One end of the sealing connection bottom sleeve 44 away from the connection bottom pipe 43 is movably sleeved on the top end of the titration bottom head 3.

[0028] Among them, the reset mechanism includes a first support frame 21 and a second support frame 31. The first support frame 21 is fixedly sleeved with the bottom end of the burette 2, and the second support frame 31 is fixedly sleeved with the top end of the burette bottom head 3. The opposite surfaces of the first support frame 21 and the second support frame 31 are fixedly connected with corresponding upper and lower first telescopic insertion rods 22 and second telescopic insertion rods 32. The proximal ends of the first telescopic insertion rod 22 and the second telescopic insertion rod 32 are sleeved with a main sleeve rod 5. A pair of snap rings 51 for clamping the first telescopic insertion rod 22 and the second telescopic insertion rod 32 into the main sleeve rod 5 are fixedly connected inside the main sleeve rod 5. The function of the snap ring 51 is to prevent the first telescopic insertion rod 22 and the second telescopic insertion rod 32 from being inserted into the main sleeve rod 5 too much or too little, resulting in the rotary piston 4 not being properly installed with the burette 2 and the burette bottom head 3. A through hole for the reset spring 52 to pass through movably is formed in the middle of the snap ring 51. A reset spring 52 is arranged inside the main sleeve rod 5. The function of the reset spring 52 is to pull the first telescopic insertion rod 22 and the second telescopic insertion rod 32 to abut against the corresponding snap rings 51, so that the rotary piston 4 is properly installed with the burette 2 and the burette bottom head 3. The two ends of the reset spring 52 are fixedly connected to the opposite ends of the first telescopic insertion rod 22 and the second telescopic insertion rod 32.

[0029] Furthermore, one end of the sealing connection top sleeve 42 connected to the bottom end of the burette 2 can expand or contract according to the caliber of the bottom end of the burette 2, and one end of the sealing connection bottom sleeve 44 connected to the top end of the burette bottom head 3 can expand or contract according to the caliber of the top end of the burette bottom head 3. The materials of the sealing connection top sleeve 42 and the sealing connection bottom sleeve 44 are both rubber.

[0030] In this embodiment, when a titration device is needed for different drug tests, the corresponding number of rotary pistons 4 are prepared according to the types of drugs. When testing one of the drugs, the test can be quickly completed through the titration device. When it is necessary to test another drug, only one hand holds the rotary piston 4, and then the other hand pulls the second support frame 31 in the direction away from the burette 2. The second support frame 31 slides telescopically along the main sleeve rod 5 through the second telescopic insertion rod 32 thereon, so that the top end of the titration bottom head 3 can be disengaged from the sealed connection bottom sleeve 44. Then the other hand fixes the burette 2, and one hand pulls the rotary piston 4 in the direction of the titration bottom head 3, so that the bottom end of the burette 2 can be disengaged from the sealed connection top sleeve 42. Finally, the new rotary piston 4 is reversed in the above operation, which will not be elaborated here, and it can be installed at the connection end of the burette 2 and the titration bottom head 3, thus avoiding the deviation of the experimental results caused by the unclean washing of the rotary piston 4. After the new rotary piston 4 is installed at the connection end of the burette 2 and the titration bottom head 3, by squeezing the first support frame 21 and the second support frame 31, the first telescopic insertion rod 22 and the second telescopic insertion rod 32 both abut against the snap ring 51 in the main sleeve rod 5, so that the bottom end of the burette 2 is closely attached to the top end of the connecting top pipe 41, avoiding the generation of gaps between the burette 2 and the sealed connection top sleeve 42. At the same time, the top end of the titration bottom head 3 is also closely attached to the bottom end of the connecting bottom pipe 43, avoiding the generation of gaps between the titration bottom head 3 and the connecting bottom pipe 43, so as to ensure that the volume of the solution poured into the burette 2 corresponds to its scale.

[0031] The preferred embodiments of the above utility model are only used to help illustrate the utility model. The preferred embodiments do not describe all the details in detail, nor limit the utility model to the specific embodiments only. Obviously, according to the content of this specification, many modifications and changes can be made. This specification selects and specifically describes these embodiments to better explain the principle and practical application of the utility model, so that those skilled in the technical field can well understand and utilize the utility model. The utility model is only limited by the claims and their full scope and equivalents.

Claims

1. A titration device for drug inspection, comprising a bracket (1), characterized in that, It further includes: A burette (2) movably installed on the bracket (1), a burette bottom head (3) is connected to the bottom of the burette (2), a rotary piston (4) is connected to the connecting end of the burette bottom head (3) and the burette (2), and a connecting mechanism is provided on the rotary piston (4) to prevent liquid contamination during different drug inspections after the quick disassembly and assembly of the connecting end of the burette (2) and the burette bottom head (3); A reset mechanism is arranged on the burette (2) and the burette bottom head (3) to keep the distance between the burette (2) and the burette bottom head (3) unchanged before and after replacing the rotary piston (4).

2. The titration device for drug inspection according to claim 1, characterized in that, The connecting mechanism includes a connecting top pipe (41) and a connecting bottom pipe (43) fixedly connected above and below the rotary piston (4). A sealed connecting top sleeve (42) is fixedly sleeved at the top end of the connecting top pipe (41). One end of the sealed connecting top sleeve (42) away from the connecting top pipe (41) is movably sleeved with the bottom end of the burette (2). A sealed connecting bottom sleeve (44) is fixedly sleeved at the bottom end of the connecting bottom pipe (43). One end of the sealed connecting bottom sleeve (44) away from the connecting bottom pipe (43) is movably sleeved with the top end of the burette bottom head (3).

3. The titration device for drug inspection according to claim 1, characterized in that, The reset mechanism includes a first support frame (21) and a second support frame (31). The first support frame (21) is fixedly sleeved with the bottom end of the burette (2), and the second support frame (31) is fixedly sleeved with the top end of the burette bottom head (3). The opposite surfaces of the first support frame (21) and the second support frame (31) are fixedly connected with corresponding first telescopic insertion rods (22) and second telescopic insertion rods (32) up and down. The proximal ends of the first telescopic insertion rod (22) and the second telescopic insertion rod (32) are sleeved with a main sleeve rod (5). A reset spring (52) is arranged inside the main sleeve rod (5), and both ends of the reset spring (52) are fixedly connected with the opposite ends of the first telescopic insertion rod (22) and the second telescopic insertion rod (32).

4. A titration device for drug inspection according to claim 3, characterized in that, A pair of snap rings (51) are fixedly connected inside the main sleeve rod (5) for clamping the first telescopic insertion rod (22) and the second telescopic insertion rod (32) to insert into the main sleeve rod (5).

5. A titration device for drug inspection according to claim 1, characterized in that, The reset mechanism is used to prevent the rotary piston (4) from falling off the bottom end of the burette (2) and the top end of the burette bottom head (3).

6. A titration device for drug inspection according to claim 4, characterized in that, A perforation for the reset spring (52) to pass through movably is provided in the middle of the snap ring (51).

7. A titration device for drug inspection according to claim 2, characterized in that, One end of the sealed connecting top sleeve (42) connected to the bottom end of the burette (2) can expand or contract according to the diameter of the bottom end of the burette (2), and one end of the sealed connecting bottom sleeve (44) connected to the burette bottom head (3) can expand or contract according to the diameter of the top end of the burette bottom head (3). The materials of the sealed connecting top sleeve (42) and the sealed connecting bottom sleeve (44) are both rubber.

Images