A titration device for pharmaceutical development analysis

By integrating the clamping and mixing components, the shortcomings of the titration device in terms of dynamic stability and mixing efficiency are solved, enabling real-time attitude adjustment of the burette and efficient mixing of the reaction vessel, thereby improving the accuracy and safety of drug research and analysis.

CN224317588UActive Publication Date: 2026-06-02SICHUAN SUNNYHOPE PHARM CO LTD

Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SICHUAN SUNNYHOPE PHARM CO LTD
Filing Date
2025-04-08
Publication Date
2026-06-02

AI Technical Summary

Technical Problem

Existing titration devices have shortcomings in terms of dynamic stability and mixing efficiency. The burette is easily displaced by external forces, making it difficult to guarantee the uniformity of mixing, and the operation is cumbersome.

Method used

The device employs a clamping assembly in conjunction with a mounting ring and a mixing assembly. It utilizes an electric push rod, an adjusting motor, and a gyroscope to achieve real-time fine-tuning of the burette's attitude and adaptive clamping. Combined with anti-slip pads and drive teeth, it enhances the mixing efficiency and fixation safety of the reaction vessel.

Benefits of technology

Ensure the burette is vertically balanced to prevent misalignment, improve mixing efficiency, and enhance operational stability and safety.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model provides a kind of titration device for drug research and development, it is related to the field of pharmaceutical processing equipment, it includes: bottom plate, bottom plate top is used to place conical flask;Stand, bottom plate top is equipped with stand, stand one side is equipped with mounting ring, for the clamping fixation of burette;Clamping assembly, clamping assembly is equipped on the inner wall of mounting ring, for the clamping fixation of burette;And mixing assembly, mixing assembly is equipped on the top of bottom plate, for the mixing of conical flask.This kind of device cooperates through the synergistic effect of clamping assembly, realizes the real-time posture fine adjustment and self-adaptive clamping of burette, adjusts motor based on gyroscope feedback data dynamic control mounting ring angle, offset caused by compensating external force disturbance, ensure that burette is always in vertical equilibrium state;The integrated design of mixing assembly in combination with antiskid component improves the mixing efficiency and fixed safety of reaction vessel.
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Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical processing equipment, specifically a titration device for pharmaceutical research and analysis. Background Technology

[0002] In the field of pharmaceutical research and analysis, titration apparatuses are core equipment in laboratories used for precise control of liquid addition and quantitative analysis of chemical reactions. Traditional titration apparatuses typically consist of a support structure, a burette fixing mechanism, and a reaction vessel, with their functions focused on the stable clamping of the burette and the positioning of the reaction vessel. However, as drug development demands increasing experimental precision and operational efficiency, existing apparatuses have gradually become insufficient in terms of dynamic stability, anti-interference capabilities, and mixing effects, making it difficult to meet the precise control requirements of complex experimental scenarios.

[0003] Most common titration apparatuses currently employ a rigid clamping structure with a fixed support frame, using mechanical locking to achieve vertical positioning of the burette. The reaction vessel is typically placed on a static platform, relying on manual shaking or an external stirring device for mixing. While this design can accomplish basic titration operations, it has significant drawbacks in practical applications: the burette clamp lacks adaptive adjustment capabilities and is prone to displacement due to external forces; the reaction vessel fixation method is limited, and mixing efficiency is restricted by the operator's skill; furthermore, most apparatuses lack integrated anti-slip cushioning design, easily leading to vessel slippage or burette damage.

[0004] However, in actual use, the existing device has the following shortcomings: First, poor dynamic stability: the traditional clamping mechanism lacks real-time attitude adjustment function, and the burette is easily tilted by environmental vibration or operation, resulting in liquid level reading error; Second, low mixing efficiency: the reaction vessel relies on manual shaking or additional stirring equipment, making it difficult to guarantee the uniformity of mixing, and the operation is cumbersome. Utility Model Content

[0005] The present invention aims to overcome the shortcomings of the prior art by using a clamping component to hold the burette and keep it stable, while using a mixing component to fix and mechanically mix the conical flask above, thus preventing damage caused by inefficient mixing.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a titration apparatus for pharmaceutical research and analysis, comprising:

[0007] A base plate, the top of which is used to place the conical flask;

[0008] The base plate has a column at the top and a mounting ring on one side for clamping and fixing the burette.

[0009] A clamping assembly, disposed on the inner wall of the mounting ring, is used to clamp and fix the burette; and

[0010] A mixing component, located on top of the base plate, is used for mixing the conical flask.

[0011] Furthermore, the clamping assembly includes:

[0012] The mounting plate is disposed on the inner wall of the mounting ring, and the mounting plate is arranged in an arc shape.

[0013] An electric push rod is disposed on the inner wall of the mounting ring, and the end of the electric push rod is connected to the mounting plate.

[0014] Furthermore, the hybrid component includes:

[0015] A placement platform is rotatably connected to the top of the base plate, and the bottom edge of the placement platform is provided with multiple drive teeth;

[0016] A drive motor is located inside the base plate. The top of the drive motor is connected to a drive wheel via a drive shaft, and the drive wheel is meshed with the placement platform via drive teeth.

[0017] Furthermore, an adjustment motor is provided inside the column, and one side of the adjustment motor is connected to the mounting ring via a drive shaft. A gyroscope is provided inside the mounting ring, and the gyroscope is signal-connected to the adjustment motor.

[0018] Furthermore, the inner wall of the mounting plate is provided with a mounting air cushion, and the mounting air cushion is filled with air.

[0019] Furthermore, the top of the placement platform is provided with a clamping groove, and a clamping block is slidably connected inside the clamping groove. A clamping plate is provided on the top of the clamping block. A clamping rod is rotatably connected inside the clamping groove, and one end of the clamping rod protrudes from the surface of the placement platform. A threaded structure is provided on the surface of the clamping rod, and the clamping rod is engaged with the clamping block through the threaded structure.

[0020] Furthermore, the top of the placement platform is provided with an anti-slip mat, and the top of the anti-slip mat is provided with an anti-slip strip, and both the anti-slip mat and the anti-slip strip are made of rubber material.

[0021] Furthermore, a push switch is provided on one side of the base plate, and the push switch is electrically connected to the drive motor, the adjustment motor, the gyroscope and the electric push rod respectively.

[0022] This invention provides a titration device for pharmaceutical research and analysis, which has the following advantages:

[0023] The advantages of this invention are that, through the synergistic effect of the clamping components, real-time attitude fine-tuning and adaptive clamping of the burette are achieved, the adjusting motor dynamically controls the angle of the mounting ring based on gyroscope feedback data, compensates for the offset caused by external force interference, and ensures that the burette is always in a vertically balanced state; the integrated design of the mixing component and the anti-slip component improves the mixing efficiency and fixing safety of the reaction vessel. Attached Figure Description

[0024] Figure 1 This is a schematic diagram of the overall structure of this utility model.

[0025] Figure 2 This is a cross-sectional view of the overall structure of this utility model.

[0026] Figure 3 This is a schematic diagram of the mounting ring structure of this utility model.

[0027] Figure 4 This is a schematic diagram of the placement platform structure of this utility model.

[0028] Figure 5 This is a schematic diagram of the mounting plate structure of this utility model.

[0029] Figure 6 For the present utility model Figure 2 Enlarged schematic diagram of the structure at point A in the diagram.

[0030] Figure 1-6 Components: 1-Base plate; 101-Placement platform; 101a-Clamping slot; 101b-Clamping rod; 101c-Clamping block; 101d-Clamping plate; 102-Anti-slip mat; 103-Anti-slip pad strip; 104-Drive teeth; 105-Drive motor; 106-Drive wheel; 2-Column; 201-Mounting ring; 202-Adjusting motor; 203-Gyroscope; 204-Electric push rod; 205-Mounting plate; 206-Mounting air cushion; 3-Push switch. Detailed Implementation

[0031] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0032] The following disclosure provides many different embodiments or examples for implementing different structures of this application. To simplify the disclosure, specific examples of components and arrangements are described below. Of course, these are merely examples and are not intended to limit the scope of this application. Furthermore, reference numerals and / or letters may be repeated in different examples; such repetition is for simplification and clarity and does not in itself indicate a relationship between the various embodiments and / or arrangements discussed. In addition, various specific examples of processes and materials are provided in this application, but those skilled in the art will recognize the application of other processes and / or the use of other materials.

[0033] This application provides a titration device for pharmaceutical research and analysis. This device achieves real-time fine-tuning and adaptive clamping of the burette through the synergistic action of the clamping components. The adjusting motor dynamically controls the angle of the mounting ring based on gyroscope feedback data, compensating for offsets caused by external forces and ensuring the burette remains in a vertically balanced state. The integrated design of the mixing component and anti-slip component improves the mixing efficiency and fixation safety of the reaction vessel. The following provides a detailed description of this titration device for pharmaceutical research and analysis. It should be noted that the order of description in the following embodiments is not intended to limit the preferred order of the embodiments.

[0034] The present application will now be described in detail with reference to the accompanying drawings and specific embodiments.

[0035] Example 1

[0036] Please see Figure 1-6 This embodiment provides a titration device for pharmaceutical research and analysis, comprising: a base plate 1 with a conical flask placement area at the top; a column 2 vertically fixed to the top of the base plate 1; and a mounting ring 201 on the side of the column 2 for fixing a burette; a clamping assembly disposed on the inner wall of the mounting ring 201 for clamping and fixing the burette; and a mixing assembly disposed at the top of the base plate 1 for mixing the conical flask.

[0037] During use, the clamping assembly, together with the mounting ring 201, clamps and fixes the burette, while the mixing assembly, together with the conical flask placed on top of the base plate 1, fixes and drives the flask to rotate, thereby mixing and stirring the material inside the conical flask.

[0038] The clamping assembly is located on the inner wall of the mounting ring 201 and includes an arc-shaped mounting plate 205 and an electric push rod 204. The end of the electric push rod 204 is connected to the mounting plate 205. The extension and retraction of the electric push rod 204 controls the movement of the mounting plate 205. The moving mounting plate 205 applies pressure to both sides of the burette, and the pressure is used to clamp the burette.

[0039] The column 2 integrates an adjustment motor 202, whose drive shaft is connected to the mounting ring 201. The mounting ring 201 has an embedded gyroscope 203, which establishes a signal linkage with the adjustment motor 202 to dynamically adjust the attitude of the mounting ring. When the burette deviates, the gyroscope 203 will control the adjustment motor 202 to control the mounting ring 201 to rotate and fine-tune. The fine-tuning effect will keep the burette balanced and prevent the burette from tilting and making it difficult to read the value accurately.

[0040] The inner wall of the mounting plate 205 is provided with an inflatable mounting air cushion 206, which is filled with air to provide cushioning and prevent excessive clamping pressure on the burette during the clamping process, which could cause damage.

[0041] The base plate 1 has a push switch 3 on its side, which is electrically connected to the drive motor 105, the adjustment motor 202, the gyroscope 203 and the electric push rod 204 through the circuit.

[0042] Example 2

[0043] Please see Figure 1-6 In the process, the mixing component includes a placement platform 101 with multiple drive teeth 104 on its bottom edge, which mesh with the drive motor 105 inside the base plate 1 through drive wheels 106 to achieve rotation of the placement platform 101. During use, when the user presses the switch 3, the drive motor 105 can be started, which drives the placement platform 101 above to rotate. The rotation of the placement platform 101 will drive the conical flask to rotate and stir and soften the material inside, preventing the material from being difficult to mix.

[0044] The top of the placement platform 101 has a clamping groove 101a, in which a clamping block 101c is slidably connected. A clamping plate 101d is fixed on the top of the clamping block. A clamping rod 101b engages with the clamping block 101c through a threaded structure. One end of the clamping rod 101b extends out of the surface of the placement platform for manual adjustment. During the rotation of the clamping rod 101b, the clamping rod 101b will drive the clamping block 101c and the clamping plate 101d to move, and the clamping plate 101d is used to clamp and fix the conical bottle.

[0045] The top of the placement platform 101 is covered with a rubber anti-slip mat 102, and the surface is provided with raised anti-slip strips 103. The two together form an anti-slip interface. Both the anti-slip mat 102 and the anti-slip strips 103 are made of rubber material. In this way, the anti-slip mat 102 and the anti-slip strips 103 can prevent tilting, sliding and shaking.

[0046] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0047] The above provides a detailed description of a titration apparatus for pharmaceutical research and analysis provided in the embodiments of this application. Specific examples have been used to illustrate the principles and implementation methods of this application. The descriptions of the above embodiments are only for the purpose of helping to understand the technical solutions and core ideas of this application. Those skilled in the art should understand that modifications can still be made to the technical solutions described in the foregoing embodiments, or equivalent substitutions can be made to some of the technical features. These modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. A titration apparatus for pharmaceutical research and analysis, characterized in that, include: A base plate (1), the top of which is used to place a conical flask; The base plate (1) is provided with a column (2) and a mounting ring (201) is provided on one side of the column (2) for clamping and fixing the burette. A clamping assembly is disposed on the inner wall of the mounting ring (201) for clamping and fixing the burette; and A mixing component, which is located on top of the base plate (1), is used to mix the conical flask; The column (2) is equipped with an adjustment motor (202), and one side of the adjustment motor (202) is connected to the mounting ring (201) via a drive shaft. The mounting ring (201) is equipped with a gyroscope (203), and the gyroscope (203) is connected to the adjustment motor (202) via a signal. The clamping assembly includes: Mounting plate (205), the mounting plate (205) is disposed on the inner wall of the mounting ring (201), and the mounting plate (205) is arranged in an arc shape; An electric push rod (204) is provided on the inner wall of the mounting ring (201), and the end of the electric push rod (204) is connected to the mounting plate (205).

2. The titration apparatus for pharmaceutical research and analysis according to claim 1, characterized in that, The hybrid component includes: Placement platform (101) is rotatably connected to the top of the base plate (1), and the bottom edge of the placement platform (101) is provided with a plurality of drive teeth (104). A drive motor (105) is located inside the base plate (1). The top of the drive motor (105) is connected to a drive wheel (106) via a drive shaft. The drive wheel (106) is meshed with the placement platform (101) via the drive teeth (104).

3. The titration apparatus for pharmaceutical research and analysis according to claim 1, characterized in that, The mounting plate (205) has an mounting air cushion (206) on its inner wall, and the mounting air cushion (206) is filled with air.

4. The titration apparatus for pharmaceutical research and analysis according to claim 2, characterized in that, The top of the placement platform (101) is provided with a clamping groove (101a), and a clamping block (101c) is slidably connected inside the clamping groove (101a). The top of the clamping block (101c) is provided with a clamping plate (101d). A clamping rod (101b) is rotatably connected inside the clamping groove (101a), and one end of the clamping rod (101b) protrudes from the surface of the placement platform (101). The surface of the clamping rod (101b) is provided with a threaded structure, and the clamping rod (101b) is meshed with the clamping block (101c) through the threaded structure.

5. The titration apparatus for pharmaceutical research and analysis according to claim 2, characterized in that, The top of the placement platform (101) is provided with an anti-slip mat (102), and the top of the anti-slip mat (102) is provided with an anti-slip strip (103). Both the anti-slip mat (102) and the anti-slip strip (103) are made of rubber material.

6. The titration apparatus for pharmaceutical research and analysis according to claim 2, characterized in that, A push switch (3) is provided on one side of the base plate (1), and the push switch (3) is electrically connected to the drive motor (105), the adjustment motor (202), the gyroscope (203) and the electric push rod (204).