Ultra-sensitive chemiluminescence kit detection device

Abstract

The utility model relates to the technical field of kit detection equipment, in particular to an ultra-sensitive chemiluminescence kit detection device which comprises a detection table, a detection mechanism is arranged on the detection table and comprises a supporting frame, an air cylinder is arranged on the supporting frame, a movable frame is fixedly connected to the tail end of an output shaft of the air cylinder, a detection cover is connected to the inner side of the movable frame, a detection spring is connected to the top end of the detection cover, and a pull pressure sensor is fixedly connected to the tail end of the detection spring. Detection operation is performed through the arranged detection cover similar to a to-be-detected reagent bottle in structure, and reagent bottles with similar heights and different structures can be accurately recognized through different limits of the reagent bottles with different shapes on movement of the detection cover, so that the detection effect on the reagent bottles is improved, and the detection efficiency is improved. Meanwhile, the tension and pressure sensor can be matched with the detection spring, stress of the detection cover in the detection process is displayed in a concrete mode, and an operator can be prompted conveniently.

Description

Technical Field

[0001] The utility model relates to the technical field of kit detection equipment, in particular to a super-sensitive chemiluminescence kit detection device. Background Technique

[0002] A chemiluminescence detection kit is a detection kit that emits fluorescence through a chemical reaction between the reagents in the kit and the horseradish peroxidase conjugated to the secondary antibody, so that the sample can be detected by pressing an X-ray film or other appropriate chemiluminescence imaging equipment. The super-sensitive chemiluminescence detection kit can have a good luminescence detection effect on low-abundance and difficult-to-detect target proteins through its own high sensitivity. The inside of the super-sensitive chemiluminescence detection kit includes a plurality of grooves for placing different reagent bottles. Usually, during the production process of the kit, the situation of missing or misloading reagent tubes is likely to occur. Therefore, a detection device is needed to detect whether the kit is missing or misloaded, so as to ensure the ex-factory quality of the kit. In the prior art, most of the detections of the kit are carried out through a simple contact detection method, and the reagent bottles inside the kit are detected by a moving columnar detection structure.

[0003] For example, a kit detection device disclosed in the patent No. CN220563705U. In this scheme, a downward-moving pushing mechanism drives four limiting components to contact the kit and then pushes the kit to move directly below a plurality of detection components. The downward-moving pushing mechanism drives a plurality of detection components to contact the parts to be detected inside the kit. The plurality of detection components in contact with the kit and the alarm component cooperate with each other to detect the kit. This device can not only position the kit but also detect whether it is missing or misloaded. It not only has simple operation but also improves the detection efficiency of the kit. The contact detection structure can only detect the absence or leakage of the reagent bottles inside the kit. When the reagent bottles inside the kit are misloaded, especially when the reagent bottles with similar heights are misloaded, the contact detection structure cannot accurately identify the misloaded reagent bottles, thus affecting the accuracy of the detection of the reagent bottles inside the kit. Content of the Utility Model

[0004] The purpose of the utility model is to provide a super-sensitive chemiluminescence kit detection device, which solves the problem that the detection structure in the prior art cannot accurately detect the misloaded reagent bottles.

[0005] To achieve the above purpose, the utility model provides the following technical solutions:

[0006] A super-sensitive chemiluminescence kit detection device includes a detection table;

[0007] A detection mechanism is provided on the detection table. The detection mechanism includes a support frame, a cylinder is provided on the support frame, a moving frame is fixedly connected to the end of the output shaft of the cylinder, a detection cover is connected inside the moving frame, a detection spring is connected to the top of the detection cover, and a tension and compression sensor is fixedly connected to the end of the detection spring.

[0008] A clamping mechanism is connected to the moving frame for clamping and positioning the reagent kit.

[0009] Preferably, a moving rod is movably connected to the top of the detection cover, a support sleeve is sleeved outside the moving rod, the detection spring is fixedly connected to the top of the moving rod, and the tension and compression sensor is fixedly connected to the inside of the moving frame.

[0010] Preferably, an air pump is fixedly connected to the moving frame, an exhaust pipe is fixedly connected to the air pump, the exhaust pipe is interconnected with the inside of the detection cover through a pipeline, and a sealing gasket is fixedly connected to the bottom end of the detection cover.

[0011] Preferably, the clamping mechanism includes a fixing groove, the fixing groove is opened in the middle of the top end of the detection table, a clamping frame is slidably connected to the inside of the fixing groove, one end of the clamping frame passes through the detection table, a clamping roller is rotatably connected to the side of the clamping frame, and a clamping spring is fixedly connected to the side of the clamping frame away from the clamping roller.

[0012] Preferably, a driving groove is opened on the detection table, the driving groove is interconnected with the fixing groove, a driving frame is slidably connected to the inside of the driving groove, and the end of the clamping spring is fixedly connected to the driving frame.

[0013] Preferably, a driving rod is rotatably connected to the top end of the driving frame, and the end of the driving rod is rotatably connected to the side of the moving frame.

[0014] Preferably, a top plate is slidably connected to the bottom end inside the fixing groove, the bottom end of the side of the top plate abuts against a connecting rod, the connecting rod is rotatably connected to the bottom end inside the detection table, and the other end of the connecting rod abuts against a control rod, and the top end of the control rod passes through the detection table.

[0015] By means of the above technical solution, the present utility model provides a detection device for an ultrasensitive chemiluminescence reagent kit, which at least has the following beneficial effects:

[0016] (1). The present utility model performs detection operations through the detection cover with a structure similar to that of the reagent bottle to be detected. Due to the different restrictions on the movement of the detection cover by reagent bottles of different shapes, reagent bottles with similar heights but different structures can be accurately identified, improving the detection effect on the reagent bottle. At the same time, the tension and compression sensor can cooperate with the detection spring to visually display the force on the detection cover during the detection process, facilitating the prompt for the operator.

[0017] (2) The utility model can facilitate the storage of the reagent kit during the detection process through the set fixing groove structure. The detection table wall on the side of the fixing groove can block the reagent kit, thereby reducing the contact time of the reagent bottle inside the reagent kit with light in the external environment during the detection process, and thus reducing the influence of light on the reagent inside the reagent bottle during the detection process. Description of the Drawings

[0018] The drawings described herein are used to provide a further understanding of the utility model and form a part of this application:

[0019] Figure 1 Structural schematic of the utility model Figure 1 ;

[0020] Figure 2 Structural schematic of the utility model Figure 2 ;

[0021] Figure 3 Internal structural schematic of the utility model;

[0022] Figure 4 Internal structural schematic of the mobile rack of the utility model;

[0023] Figure 5 Internal structural schematic of the detection cover of the utility model.

[0024] In the figure: 1, detection table; 2, detection mechanism; 201, support frame; 202, cylinder; 203, mobile rack; 204, detection cover; 205, detection spring; 206, tension and compression sensor; 207, mobile rod; 208, support sleeve; 209, air pump; 210, exhaust pipe; 211, gasket; 3, clamping mechanism; 301, fixing groove; 302, clamping frame; 303, clamping roller; 304, clamping spring; 305, driving groove; 306, driving frame; 307, driving rod; 308, ejector plate; 309, connecting rod; 310, control rod. Detailed Embodiment

[0025] Next, the technical solutions in the embodiments of the utility model will be clearly and completely described in conjunction with the drawings in the embodiments of the utility model. Obviously, the described embodiments are only a part of the embodiments of the utility model, rather than all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by those of ordinary skill in the art without making creative efforts shall fall within the protection scope of the utility model.

[0026] Embodiment 1

[0027] A highly sensitive chemiluminescent reagent kit detection device, as Figures 1 - 5As shown in the figure, it includes a detection table 1; a detection mechanism 2 is provided on the detection table 1. The detection mechanism 2 can perform detection operations on the reagent bottles inside the ultrasensitive chemiluminescence kit, and conveniently identify missing or misaligned reagent bottles, thereby improving the detection effect of the kit.

[0028] Specifically, the detection mechanism 2 includes a support frame 201. The structure of the support frame 201 can support the entire detection mechanism 2. A cylinder 202 is provided on the support frame 201. The structure of the cylinder 202 can drive the detection structure, enabling the detection structure to perform lifting and adjustment operations. The end of the output shaft of the cylinder 202 is fixedly connected to a moving frame 203. The structure of the moving frame 203 can support the detection components. At the same time, the moving frame 203 can move up and down under the drive of the cylinder 202 and drive the detection components to move synchronously. The inner side of the moving frame 203 is connected to a detection cover 204. The detection cover 204 is the main detection component, which can perform precise detection operations on the reagent bottles inside the kit, so as to prompt the operator when there is a missing reagent bottle or the reagent bottle is placed misaligned. The internal structure of the detection cover 204 corresponds to the top structure of the reagent bottle to be detected. Therefore, when reagent bottles with different shapes are placed misaligned, the force on the detection cover 204 is different, realizing the detection operation of the misaligned reagent bottle. A detection spring 205 is connected to the top of the detection cover 204. The detection spring 205 can convert the force on the detection cover 204 into elastic deformation of the detection spring 205. The end of the detection spring 205 is fixedly connected to a tensile and compressive force sensor 206. The tensile and compressive force sensor 206 can convert the elastic force of the detection spring 205 into data, so as to compare the detection data with the preset data and prompt the operator when the data is different.

[0029] A moving rod 207 is movably connected to the top of the detection cover 204. The movably connected moving rod 207 facilitates the installation and disassembly operations of the detection cover 204, so as to replace the detection cover 204. When performing detection operations on different kits, the detection cover 204 can be replaced according to the shape of the reagent bottles inside the kit, thereby improving the detection accuracy. A support sleeve 208 is sleeved on the outside of the moving rod 207. The detection spring 205 is fixedly connected to the top of the moving rod 207. The tensile and compressive force sensor 206 is fixedly connected inside the moving frame 203. The structure of the support sleeve 208 can support and guide the moving rod 207, enabling the moving rod 207 to only move and adjust inside the support sleeve 208. At the same time, the detection spring 205 fixed to the top of the moving rod 207 can be restricted by the support sleeve 208, preventing the detection spring 205 from bending sideways when being squeezed. At the same time, the detection spring 205 is connected to the moving rod 207, which facilitates the connection of the detection spring 205 with different detection covers 204 and performs detection operations.

[0030] An air pump 209 is fixedly connected to the mobile frame 203, and an exhaust pipe 210 is fixedly connected to the air pump 209. The exhaust pipe 210 is interconnected with the inside of the detection cover 204 through a pipeline. The air pump 209 can extract the gas inside the detection cover 204 through the connected pipeline, so that a negative pressure environment is formed inside the detection cover 204. A sealing pad 211 is fixedly connected to the bottom end of the detection cover 204. The sealing pad 211 structure can block the gap at the connection when the detection cover 204 abuts against the top of the reagent bottle, and cooperates with the air pump 209 to form a suction cup structure for the detection cover 204, so that the reagent bottle can be driven to rise synchronously when the detection cover 204 rises, so as to detect the weight inside the reagent bottle, so that the reagent bottles that are missing or have different weights can be quickly identified, and the detection effect of the reagent kit can be improved.

[0031] Example 2

[0032] like Figure 1 , Figure 3 As shown, on the basis of Example 1, the mobile frame 203 is connected with a clamping mechanism 3, which can clamp and fix the reagent kit to be tested, thereby improving the stability of the reagent kit during the testing process and the detection accuracy of the detection mechanism 2 on the reagent kit.

[0033] In this embodiment, the clamping mechanism 3 includes a fixed groove 301, which is opened in the middle of the top of the detection platform 1. The fixed groove 301 structure can place the test kit, and the fixed groove 301 can shade the test kit through the side wall of the detection platform 1, thereby reducing the contact time of the reagent bottle with the bright environment during the test. The inner side of the fixed groove 301 is slidably connected with a clamping frame 302, one end of the clamping frame 302 is set through the detection platform 1, and the side of the clamping frame 302 is rotatably connected with a clamping roller 303, and the side of the clamping frame 302 away from the clamping roller 303 is fixedly connected with a clamping spring 304, and the clamping frame 302 structure can support the clamping roller 303, and clamp the test kit through the vertically placed clamping roller 303, and the rotating connected clamping roller 303 does not affect the adjustment of the test kit in the horizontal direction while clamping and fixing the test kit, so that the test kit can be moved to the center of the fixed groove 301 during the clamping process, thereby improving the positioning effect of the test kit.

[0034] A driving slot 305 is provided on the detection table 1, and the driving slot 305 is communicated with the fixed slot 301. A driving frame 306 is slidably connected inside the driving slot 305, and the end of the clamping spring 304 is fixedly connected to the driving frame 306. The driving frame 306 structure can drive the clamping spring 304 and the clamping frame 302 to make the clamping frame 302 approach or move away from the test kit, and when approaching the test kit, the test kit is clamped by the elasticity of the compressed clamping spring 304.

[0035] The top end of the driving frame 306 is rotatably connected to a driving rod 307, and the end of the driving rod 307 is rotatably connected to the side surface of the moving frame 203. The structure of the driving rod 307 can link the driving frame 306 and the moving frame 203. When detecting, the downward movement of the moving frame 203 drives the driving frame 306 to move inward synchronously to clamp the reagent kit.

[0036] A top plate 308 is slidably connected to the inner bottom end of the fixing groove 301. The structure of the top plate 308 facilitates the removal of the reagent kit that has completed the detection. The bottom end of the side surface of the top plate 308 abuts against a connecting rod 309. The connecting rod 309 is rotatably connected to the inner bottom end of the detection table 1. The other end of the connecting rod 309 abuts against a control rod 310. The top end of the control rod 310 passes through the detection table 1. The structure of the connecting rod 309 can transmit the movement of the control rod 310 to the top plate 308, so that the operator can conveniently drive the top plate 308 through the control rod 310.

[0037] When the ultra-sensitive chemiluminescent reagent kit detection device of the utility model is used, the ultra-sensitive chemiluminescent reagent kit to be detected is first placed inside the fixed groove 301, and the cylinder 202 is started after the box cover of the reagent kit is opened, and the cylinder 202 then drives the mobile frame 203 to move downward. The driving rod 307 on the side of the mobile frame 203 then drives the driving frame 306 to move inward, and the clamping spring 304 on the inner side of the driving frame 306 and the clamping frame 302 then continue to approach the reagent kit. After the clamping roller 303 contacts the reagent kit, the clamping frame 302 stops moving, and the driving frame 306 that continues to approach compresses the clamping spring 304, and the clamping spring 304 continuously pushes the clamping frame 302 and the clamping roller 303 toward the reagent kit through elasticity and clamps and fixes the reagent kit. The detection cover 204 at the bottom of the mobile frame 203 continues to descend with the mobile frame 203, and the detection cover 204 then moves to the inside of the opened reagent kit. When the detection cover 204 moves to contact with the corresponding reagent bottle, there is still a small distance between the movable frame 203 and the lowest end of the descent. After the movable frame 203 continues to descend, the detection cover 204 in contact with the corresponding reagent bottle compresses the detection spring 205 under the restriction of the reagent bottle, and the compressed detection spring 205 squeezes the pull pressure sensor 206, and obtains a pressure value through the pull pressure sensor 206. The pressure value of the detection cover 204 when detecting a normal reagent bottle is close to the preset value. When the reagent bottle is misplaced, the pressure value of the detection cover 204 when contacting a reagent bottle with a large volume is greater than the preset value. When the detection cover 204 detects a missing position or loads a reagent bottle with a smaller volume, the detection cover 204 cannot be restricted by the reagent bottle or is less restricted by the reagent bottle. At this time, the detected pressure value is less than the preset value. By comparing the values, the missing or misplaced reagent bottles inside the test kit can be conveniently detected. Then the air pump 209 is started and the air inside the detection cover 204 is extracted, and a negative pressure environment is formed inside the detection cover 204. At the same time, the cylinder 202 drives the mobile frame 203 to continue to rise. The detection cover 204 sealed by the sealing pad 211 drives the reagent bottle upward synchronously after rising. When the bottom of the reagent bottle is separated from the inner bottom of the test kit, the reagent bottle stretches the detection spring 205 under the weight of the internal reagent, and the tension pressure sensor 206 can obtain the tension value. The operator can detect the reagent bottles of different weights according to the tension value detected. After completing the detection operation, the air pump 209 is turned off, and the gas flows back to the inside of the detection cover 204, and the reagent bottle falls into the inside of the test kit.While the moving frame 203 moves away from the detection table 1, the driving frame 306 is moved outward by the driving rod 307, and the clamping force on the reagent kit is reduced accordingly. After closing the lid of the reagent kit, the control rod 310 is pressed downward. The control rod 310 then presses one end of the connecting rod 309 downward, and the other end of the connecting rod 309 drives the ejector plate 308 upward to eject the reagent kit, facilitating the operator to take the reagent kit.

[0038] It should be noted that in this text, relational terms such as first and second are only used to distinguish one entity or operation from another entity or operation, and do not necessarily require or imply any actual relationship or order between these entities or operations. Moreover, the term "comprising", "including" or any other variant thereof is intended to cover non-exclusive inclusion, so that a process, method, article or device comprising a series of elements not only includes those elements, but also includes other elements not expressly listed, or elements inherent to such process, method, article or device.

[0039] Although the embodiments of the present invention have been shown and described, for those of ordinary skill in the art, it can be understood that various changes, modifications, substitutions and variations can be made to these embodiments without departing from the principles and spirit of the present invention. The scope of the present invention is defined by the appended claims and their equivalents.

Claims

1. An ultrasensitive chemiluminescence kit detection device, comprising a detection table (1), characterized in that: A detection mechanism (2) is provided on the detection table (1). The detection mechanism (2) includes a support frame (201). A cylinder (202) is provided on the support frame (201). The end of the output shaft of the cylinder (202) is fixedly connected to a moving frame (203). A detection cover (204) is connected inside the moving frame (203). A detection spring (205) is connected to the top of the detection cover (204). The end of the detection spring (205) is fixedly connected to a tension and compression sensor (206). A clamping mechanism (3) is connected to the moving frame (203) for clamping and positioning the reagent kit.

2. The detection device for an ultrasensitive chemiluminescence kit according to claim 1, wherein: A moving rod (207) is movably connected to the top of the detection cover (204). A support sleeve (208) is sleeved outside the moving rod (207). The detection spring (205) is fixedly connected to the top of the moving rod (207). The tension and compression sensor (206) is fixedly connected inside the moving frame (203).

3. The ultrasensitive chemiluminescence kit detection device according to claim 1, characterized in that: An air pump (209) is fixedly connected to the moving frame (203). An exhaust pipe (210) is fixedly connected to the air pump (209). The exhaust pipe (210) is interconnected with the inside of the detection cover (204) through a pipe. A sealing gasket (211) is fixedly connected to the bottom end of the detection cover (204).

4. The ultrasensitive chemiluminescence kit detection device according to claim 1, wherein: The clamping mechanism (3) includes a fixing groove (301). The fixing groove (301) is opened in the middle of the top end of the detection table (1). A clamping frame (302) is slidably connected inside the fixing groove (301). One end of the clamping frame (302) passes through the detection table (1). A clamping roller (303) is rotatably connected to the side of the clamping frame (302). A clamping spring (304) is fixedly connected to the side of the clamping frame (302) away from the clamping roller (303).

5. The super-sensitive chemiluminescence kit detection device according to claim 4, characterized in that: A driving groove (305) is opened on the detection table (1). The driving groove (305) is interconnected with the fixing groove (301). A driving frame (306) is slidably connected inside the driving groove (305). The end of the clamping spring (304) is fixedly connected to the driving frame (306).

6. The detection device of an ultrasensitive chemiluminescence kit according to claim 5, characterized in that: A driving rod (307) is rotatably connected to the top of the driving frame (306). The end of the driving rod (307) is rotatably connected to the side of the moving frame (203).

7. The detection device of an ultrasensitive chemiluminescence kit according to claim 4, characterized in that: A top plate (308) is slidably connected to the bottom end inside the fixing groove (301). The bottom end of the side of the top plate (308) abuts against a connecting rod (309). The connecting rod (309) is rotatably connected to the bottom end inside the detection table (1). The other end of the connecting rod (309) abuts against a control rod (310). The top end of the control rod (310) passes through the detection table (1).

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