Smoking device based on chronic obstructive pulmonary disease animal model

Abstract

The utility model relates to the technical field of animal model smoking devices, in particular to a chronic obstructive pulmonary disease-based animal model smoking device which comprises a test box, a sealing cover is hinged to the top end of the test box, a plurality of through holes are formed in the sealing cover, a machine shell is arranged on the rear side of the top end of the sealing cover, and a plurality of through holes are formed in the machine shell. An adjusting assembly is arranged in an inner cavity of the machine shell, a moving plate is arranged at the front end of the adjusting assembly, an adjusting plate is arranged at the front end of the moving plate, a plurality of telescopic rods are arranged on the rear side of the inner cavity of the machine shell, the front ends of the telescopic rods are fixedly connected with the moving plate, and a support is arranged at the bottom end of an inner cavity of the test box. The smoking device for the animal model based on the chronic obstructive pulmonary disease solves the problem that the smoking device for the animal model based on the chronic obstructive pulmonary disease in the prior art is limited in flexibility in the using process due to the fact that the smoke concentration is inconvenient to adjust according to experimental requirements in the actual using process of the smoking device for the animal model based on the chronic obstructive pulmonary disease.

Description

Technical Field

[0001] The utility model relates to the technical field of animal model fumigation devices, in particular to a fumigation device based on an animal model of chronic obstructive pulmonary disease. Background Art

[0002] Chronic obstructive pulmonary disease (COPD) is a disease associated with an abnormal inflammatory response in the lungs to harmful gases or particles, such as cigarette smoke, leading to chronic inflammation in the airways, lung parenchyma, pulmonary vasculature, and throughout the body. COPD has become the fourth leading cause of death worldwide, after cardiovascular disease, cerebrovascular disease, and acute respiratory infections, and tied with AIDS. It is also one of the fastest-growing diseases in developing countries, with the mortality rate of COPD doubling in the past 30 years. The WHO predicts that COPD will become the third leading cause of death worldwide by 2020. Due to the current lack of understanding of the exact pathogenesis of COPD, the establishment of a long-term, stable animal model that simulates human COPD provides an important technical tool for in-depth research on its pathogenesis and the exploration of prevention and treatment methods. However, the COPD animal models currently used both domestically and internationally rely on traditional fumigation methods.

[0003] However, the existing fumigation device based on an animal model of chronic obstructive pulmonary disease is not convenient for adjusting the smoke concentration according to experimental requirements during actual use, resulting in limited flexibility during use. To address this problem, a fumigation device based on an animal model of chronic obstructive pulmonary disease is provided. Utility Model Content

[0004] The purpose of the present invention is to provide a fumigation device based on an animal model of chronic obstructive pulmonary disease to solve the problems raised in the above-mentioned background technology. To achieve the above-mentioned purpose, the present invention provides the following technical solutions: a fumigation device based on an animal model of chronic obstructive pulmonary disease, comprising a test box, a sealing cover hinged at the top end of the test box, a plurality of through holes provided on the sealing cover, a shell provided at the rear side of the top end of the sealing cover, an adjustment component provided in the inner cavity of the shell, a movable plate provided at the front end of the adjustment component, an adjustment plate provided at the front end of the movable plate, a plurality of telescopic rods provided at the rear side of the inner cavity of the shell, the front ends of the plurality of telescopic rods being fixedly connected to the movable plate, a bracket provided at the bottom end of the inner cavity of the test box, a plurality of fixing holes provided on the bracket for fixing cigarettes, a fixing component provided in the inner cavity of the test box, a mesh box detachably placed at the bottom end of the inner cavity of the test box, and the mesh box being sleeved on the outside of the bracket.

[0005] Preferably, the fixing assembly includes a cylinder and a clamping plate, the two cylinders are respectively arranged on the left and right sides of the inner cavity of the test box, and the two clamping plates are respectively arranged at the output ends of the two cylinders.

[0006] Preferably, anti-slip edges are provided on the sides of the two clamping plates that are close to each other.

[0007] Preferably, the adjusting assembly includes a motor, a screw, a slider, a fixing seat, a connecting rod and a limit assembly. The motor is arranged at the right end of the casing, and the output end of the motor extends to the inner cavity of the casing. One end of the screw is rotatably connected to the left side of the inner cavity of the casing through a bearing, and the other end of the screw is fixedly connected to the output end of the motor. The two sliders are respectively screwed on the left and right sides of the outer wall of the screw, and the fixing seat is arranged on the rear side of the movable plate. One end of the two connecting rods is respectively hinged to the front end of the two sliders, and the other end of the two connecting rods is respectively hinged to the left and right sides of the rear end of the fixing seat. The limit assembly is arranged on the rear side of the inner cavity of the casing and is respectively fixedly connected to the two sliders.

[0008] Preferably, the limiting assembly includes a limiting slot and a limiting block, the limiting slot is opened on the rear side of the inner cavity of the casing, and the two limiting blocks can be slidably embedded in the inner cavity of the limiting slot and fixedly connected to the two sliders.

[0009] Preferably, the inner cavity of the limiting groove and the outer wall of the limiting block are matched and both are dovetail-shaped.

[0010] Preferably, the threads on the left and right sides of the outer wall of the screw rod are arranged opposite to each other.

[0011] Compared with the prior art, the present invention has the following beneficial effects:

[0012] 1. By inserting the cigarette into the fixing hole, sleeve-mounting the mesh cage on the outside of the bracket, and extending the output end of the cylinder, the two clamps fix the mesh cage to the bottom end of the inner cavity of the test chamber, thereby preventing the animal from coming into contact with the cigarette. The smoke can be discharged through the provision of the through hole. The adjustment component drives the movable plate and the adjustment plate to slide to cover the through hole, thereby adjusting the speed of smoke discharge, so that the smoke in the inner cavity of the test chamber can be kept at different concentrations. This solves the problem that the existing smoke fumigation device based on the chronic obstructive pulmonary disease animal model is not convenient for adjusting the smoke concentration according to experimental requirements during actual use, resulting in limited flexibility during use. BRIEF DESCRIPTION OF THE DRAWINGS

[0013] Figure 1 It is a schematic diagram of the three-dimensional structure of the utility model;

[0014] Figure 2 This is a main sectional view of the test box of the utility model;

[0015] Figure 3 This is a structural diagram of the utility model cage;

[0016] Figure 4 This is a top sectional view of the housing of the utility model;

[0017] Figure 5 For this utility model Figure 4 Enlarged view of point A.

[0018] In the figure: 1. Test box; 2. Sealing cover; 3. Casing; 4. Telescopic rod; 5. Moving plate; 6. Adjusting plate; 7. Through hole; 8. Bracket; 9. Fixing hole; 10. Net box; 11. Cylinder; 12. Clamp; 13. Motor; 14. Screw; 15. Slider; 16. Fixing seat; 17. Connecting rod; 18. Limiting groove; 19. Limiting block. DETAILED DESCRIPTION

[0019] The following will be combined with the drawings in the embodiments of the present invention to clearly and completely describe the technical solutions in the embodiments of the present invention. Obviously, the embodiments described are only part of the embodiments of the present invention, not all of the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by ordinary technical personnel in this field without making creative efforts shall fall within the scope of protection of the present invention.

[0020] See also Figures 1 to 5 The utility model provides a technical solution: a smoking device based on an animal model of chronic obstructive pulmonary disease, comprising a test box 1, a sealing cover 2 hinged at the top of the test box 1, a plurality of through holes 7 being opened on the sealing cover 2, a shell 3 being arranged on the rear side of the top of the sealing cover 2, an inner cavity of the shell 3 being arranged with an adjustment component, a movable plate 5 being arranged at the front end of the adjustment component, an adjustment plate 6 being arranged at the front end of the movable plate 5, a plurality of telescopic rods 4 being arranged on the rear side of the inner cavity of the shell 3, the front ends of the plurality of telescopic rods 4 being fixedly connected to the movable plate 5, a bracket 8 being arranged at the bottom end of the inner cavity of the test box 1, a plurality of fixing holes 9 being opened on the bracket 8 for fixing cigarettes, a fixing component being arranged in the inner cavity of the test box 1, a mesh box 10 being detachably placed at the bottom end of the inner cavity of the test box 1, the mesh The box 10 is sleeved on the outside of the bracket 8. By inserting the cigarette into the fixing hole 9, the net box 10 is sleeved on the outside of the bracket 8, and the output end of the cylinder 11 is extended, the two clamps 12 fix the net box 10 to the bottom end of the inner cavity of the test box 1, which can prevent the animal from coming into contact with the cigarette. The smoke can be discharged by setting the through hole 7. The movable plate 5 and the adjustment plate 6 are driven by the adjustment component to slide to cover the through hole 7, and then the speed of smoke discharge can be adjusted, so that the smoke in the inner cavity of the test box 1 can be at different concentrations, which solves the problem that the existing technology of the chronic obstructive pulmonary disease animal model fumigation device is not convenient to adjust the smoke concentration according to experimental requirements during actual use, resulting in limited flexibility during use.

[0021] In this embodiment, the fixing assembly includes a cylinder 11 and a clamp 12. The two cylinders 11 are respectively arranged on the left and right sides of the inner cavity of the test box 1, and the two clamps 12 are respectively arranged at the output ends of the two cylinders 11. When the cylinder 11 is started, the output end of the cylinder 11 is extended, and then the two clamps 12 clamp the net box 10 to prevent animals from overturning the net box 10 and damaging the cigarettes.

[0022] In this embodiment, anti-slip edges are provided on the sides of the two clamping plates 12 that are close to each other, which can increase the roughness of the outer walls of the clamping plates 12 and further increase the friction between the clamping plates 12 and the mesh box 10.

[0023] In this embodiment, the adjustment assembly includes a motor 13, a screw rod 14, a slider 15, a fixing seat 16, a connecting rod 17 and a limit assembly. The motor 13 is arranged at the right end of the casing 3, and the output end of the motor 13 extends to the inner cavity of the casing 3. One end of the screw rod 14 is rotatably connected to the left side of the inner cavity of the casing 3 through a bearing, and the other end of the screw rod 14 is fixedly connected to the output end of the motor 13. The two sliders 15 are respectively screwed on the left and right sides of the outer wall of the screw rod 14. The fixing seat 16 is arranged on the rear side of the movable plate 5. One end of the two connecting rods 17 is respectively hinged to the front end of the two sliders 15, and the other end of the two connecting rods 17 is respectively hinged to the left and right sides of the rear end of the fixing seat 16. The limit assembly is arranged on the rear side of the inner cavity of the casing 3 and is respectively fixed to the two sliders 15 Connect and start the motor 13, so that the motor 13 drives the screw rod 14 to rotate, and then the opposite threads on the left and right sides of the outer wall of the screw rod 14 generate relative thread rotation force, so that the two sliders 15 slide toward the middle of the screw rod 14 at the same time under the limiting action of the limiting groove 18 and the limiting block 19, so that the two connecting rods 17 push the movable plate 5 and the adjustment plate 6 to slide along a straight line under the limiting action of multiple telescopic rods 4 to cover the through hole 7, and then the speed of smoke discharge can be adjusted, so that the smoke in the inner cavity of the test box 1 can be at different concentrations, which solves the problem that the existing technology of the fumigation device based on the chronic obstructive pulmonary disease animal model is not convenient to adjust the smoke concentration according to experimental requirements during actual use, resulting in limited flexibility during use.

[0024] In this embodiment, the limiting assembly includes a limiting groove 18 and a limiting block 19. The limiting groove 18 is opened on the rear side of the inner cavity of the casing 3. The two limiting blocks 19 can be slidably embedded in the inner cavity of the limiting groove 18 and fixedly connected to the two sliders 15. Under the joint action of the limiting groove 18 and the limiting block 19, the slider 15 can be prevented from rotating with the screw rod 14 when the screw rod 14 rotates, thereby improving the stability of the adjustment assembly during use.

[0025] In this embodiment, the inner cavity of the limiting groove 18 is adapted to the outer wall of the limiting block 19 and both are dovetail-shaped, so that one end of the limiting block 19 can always remain embedded in the inner cavity of the limiting groove 18, thereby improving the stability of the limiting assembly during use.

[0026] In this embodiment, the threads on the left and right sides of the outer wall of the screw rod 14 are arranged relative to each other, so that when the screw rod 14 rotates, the left and right sides of its outer wall generate relative thread rotation forces, thereby causing the two sliders 15 to slide relative to each other at the same time under the limiting action of the limiting groove 18 and the limiting block 19.

[0027] The usage and advantages of this utility model: When in use, the working process is as follows:

[0028] Insert a lit cigarette into the fixing hole 9, place the net box 10 at the bottom of the inner cavity of the test box 1 and sleeve it on the outside of the bracket 8, start the cylinder 11, extend the output end of the cylinder 11, and then make the two clamps 12 clamp the net box 10, place the test animal into the inner cavity of the test box 1 and cover the sealing cover 2 tightly. Through the setting of the through hole 7, the smoke can be discharged, start the motor 13, and make the motor 13 drive the screw rod 14 to rotate, so that the opposite threads on the left and right sides of the outer wall of the screw rod 14 generate relative thread rotation force, so that the two sliders 15 are in the limit position. Under the limiting action of the groove 18 and the limit block 19, they slide toward the middle of the screw rod 14 at the same time, so that the two connecting rods 17 push the movable plate 5 and the adjustment plate 6 to slide along a straight line under the limiting action of multiple telescopic rods 4 to cover the through hole 7, thereby adjusting the speed of smoke exhaust, so that the smoke in the inner cavity of the test box 1 can be at different concentrations, which solves the problem that the existing technology of the fumigation device based on the chronic obstructive pulmonary disease animal model is not convenient to adjust the smoke concentration according to experimental requirements during actual use, resulting in limited flexibility during use.

[0029] The above shows and describes the basic principles, main features, and advantages of the present invention. Persons skilled in the art should understand that the present invention is not limited to the above-described embodiments. The above-described embodiments and descriptions are merely preferred examples of the present invention and are not intended to limit the present invention. Various changes and improvements may be made to the present invention without departing from the spirit and scope of the present invention, and such changes and improvements fall within the scope of the present invention. The scope of protection claimed in the present invention is defined by the appended claims and their equivalents.

Claims

1. A fumigation device for an animal model of chronic obstructive pulmonary disease, comprising a test chamber (1), characterized in that: The top of the test box (1) is hinged with a sealing cover (2), and a plurality of through holes (7) are provided on the sealing cover (2). A housing (3) is provided at the rear side of the top of the sealing cover (2), and an adjustment component is provided in the inner cavity of the housing (3). A movable plate (5) is provided at the front end of the adjustment component, and an adjustment plate (6) is provided at the front end of the movable plate (5). A plurality of telescopic rods (4) are provided at the rear side of the inner cavity of the housing (3), and the front ends of the plurality of telescopic rods (4) are fixedly connected to the movable plate (5). A bracket (8) is provided at the bottom end of the inner cavity of the test box (1), and a plurality of fixing holes (9) are provided on the bracket (8) for fixing cigarettes. The inner cavity of the test box (1) is provided with a fixing component, and a mesh box (10) is detachably placed at the bottom end of the inner cavity of the test box (1), and the mesh box (10) is sleeved on the outside of the bracket (8).

2. The fumigation device for the animal model of chronic obstructive pulmonary disease according to claim 1, characterized in that: The fixing assembly comprises a cylinder (11) and a clamping plate (12), wherein the two cylinders (11) are respectively arranged on the left and right sides of the inner cavity of the test box (1), and the two clamping plates (12) are respectively arranged at the output ends of the two cylinders (11).

3. The fumigation device for the animal model of chronic obstructive pulmonary disease according to claim 2, characterized in that: Anti-slip edges are provided on the sides of the two clamping plates (12) that are close to each other.

4. The fumigation device for the animal model of chronic obstructive pulmonary disease according to claim 1, characterized in that: The adjusting assembly comprises a motor (13), a screw rod (14), a slider (15), a fixing seat (16), a connecting rod (17) and a limit assembly. The motor (13) is arranged at the right end of the casing (3). The output end of the motor (13) extends to the inner cavity of the casing (3). One end of the screw rod (14) is rotatably connected to the left side of the inner cavity of the casing (3) through a bearing. The other end of the screw rod (14) is fixedly connected to the output end of the motor (13). The two sliders (15) are respectively screwed on the left and right sides of the outer wall of the screw rod (14). The fixing seat (16) is arranged on the rear side of the movable plate (5). One end of the two connecting rods (17) is respectively hinged to the front end of the two sliders (15). The other end of the two connecting rods (17) is respectively hinged to the left and right sides of the rear end of the fixing seat (16). The limit assembly is arranged on the rear side of the inner cavity of the casing (3) and is respectively fixedly connected to the two sliders (15).

5. The fumigation device for the animal model of chronic obstructive pulmonary disease according to claim 4, characterized in that: The limiting assembly comprises a limiting groove (18) and a limiting block (19), wherein the limiting groove (18) is provided at the rear side of the inner cavity of the housing (3), and the two limiting blocks (19) are both slidably embedded in the inner cavity of the limiting groove (18) and fixedly connected to the two sliders (15).

6. The fumigation device for the animal model of chronic obstructive pulmonary disease according to claim 5, characterized in that: The inner cavity of the limiting groove (18) and the outer wall of the limiting block (19) are adapted to each other and both are dovetail-shaped.

7. The fumigation device for the animal model of chronic obstructive pulmonary disease according to claim 4, characterized in that: The threads on the left and right sides of the outer wall of the screw rod (14) are arranged opposite to each other.

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