Drug delivery device for radiotherapy and chemotherapy

Abstract

The utility model provides a radiotherapy and chemotherapy dosing device, which comprises a main tube body, which is internally provided with a radiotherapy liquid channel and a chemotherapy liquid channel which are not communicated with each other; the radiotherapy assembly comprises a first liquid inlet assembly and a first storage bag, the first liquid inlet assembly is arranged at the first end of the main catheter body and communicated with the radiotherapy liquid channel, and the first storage bag is arranged at the second end of the main catheter body and communicated with the radiotherapy liquid channel; and the chemotherapy assembly comprises a second liquid inlet assembly, the second liquid inlet assembly is arranged at the first end of the main pipe body and communicates with the chemotherapy liquid channel, a first liquid outlet hole communicating with the chemotherapy liquid channel is formed in the second end of the main pipe body, and the first liquid outlet hole is exposed out of the outer side surface of the main pipe body and is staggered from the first storage bag. After the device is placed, accurate and effective radiotherapy and chemotherapy can be carried out at the tumor position, repeated operations are not needed, the risk that brain tissue of a patient is injured and infected is reduced, and the service life of the patient is prolonged.

Description

Technical Field

[0001] The utility model relates to the technical field of medical devices, in particular to a radiotherapy and chemotherapy drug delivery device. Background Art

[0002] In the relevant technologies, surgery, radiotherapy, and chemotherapy are currently commonly used to treat tumors in a coordinated manner. Radiotherapy generally involves placing a radioactive source into a human cavity or tumor tissue for close-range irradiation therapy. Replacing or removing the radioactive source often requires craniotomy. Chemotherapy, when performed via intravenous injection, is a common method for treating tumors. However, most chemotherapy drugs cannot penetrate the blood-brain barrier. By the time the chemotherapy solution reaches the tumor site, its concentration has been greatly reduced, resulting in poor efficacy. Increasing the drug dosage can lead to serious systemic toxic side effects, requiring multiple doses of both radiotherapy and chemotherapy, which can damage the patient's brain tissue and increase the risk of infection. Utility Model Content

[0003] The technical problem to be solved by the present invention is to provide a radiotherapy and chemotherapy drug delivery device, which aims to solve the problem in the related art that radiotherapy and chemotherapy may cause damage to the patient's brain tissue and the risk of infection due to repeated treatment.

[0004] In order to solve the above technical problems, the present invention provides a radiotherapy and chemotherapy drug delivery device, comprising:

[0005] A main body, having a radiotherapy fluid channel and a chemotherapy fluid channel that are not connected to each other, and the main body having a first end and a second end that are oppositely distributed along the length direction thereof;

[0006] a radiotherapy assembly comprising a first liquid inlet assembly and a first storage capsule, wherein the first liquid inlet assembly is disposed at a first end of the main body and communicates with the radiotherapy fluid channel, and the first storage capsule is disposed at a second end of the main body and communicates with the radiotherapy fluid channel; and

[0007] The chemotherapy component includes a second liquid inlet component, which is arranged at the first end of the main body and is connected to the chemotherapy liquid channel. The second end of the main body is provided with a first liquid outlet hole connected to the chemotherapy liquid channel. The first liquid outlet hole is exposed on the outer surface of the main body and is staggered with the first storage bag.

[0008] Optionally, the lengths of the radiotherapy fluid channel and the chemotherapy fluid channel both extend along the axial direction of the main body, and the radiotherapy fluid channel and the chemotherapy fluid channel are parallel to each other.

[0009] Optionally, a second liquid outlet is provided at the second end of the main body, and the second liquid outlet is connected to the radiotherapy fluid channel and the first storage bag respectively.

[0010] Optionally, the second liquid outlet is exposed on the outer surface of the main body, and the first storage bag covers the second liquid outlet.

[0011] Optionally, the first liquid inlet component includes:

[0012] a first branch tube body connected to a first end of the main tube body, the first branch tube body being provided with a first liquid inlet channel communicating with the radiotherapy fluid channel, the first liquid inlet channel including a first liquid inlet port formed in the first branch tube body; and

[0013] The first cap is connected to one end of the first branch pipe body away from the main pipe body, and the first cap covers the first liquid inlet.

[0014] Optionally, the second end of the main body extends to the outside of the first storage bag, and the first liquid outlet is provided at the portion of the main body extending to the outside of the first storage bag.

[0015] Optionally, the second liquid inlet component includes:

[0016] a second branch tube body connected to the first end of the main tube body, the second branch tube body being provided with a second liquid inlet channel communicating with the radiotherapy fluid channel, the second liquid inlet channel including a second liquid inlet port formed in the second branch tube body; and

[0017] The second cap is connected to one end of the second branch pipe body away from the main pipe body, and the second cap covers the second liquid inlet.

[0018] Optionally, the second liquid inlet component further includes a second storage bag, which is respectively connected to the first end of the main pipe body and the second branch pipe body, and the second storage bag is respectively connected to the chemotherapy fluid channel and the second liquid inlet channel.

[0019] Optionally, the second liquid inlet component includes:

[0020] a second storage bag connected to the first end of the main body, and the second storage bag is in communication with the chemotherapy fluid channel;

[0021] A second branch tube body is connected to the second storage bag, the second branch tube body is provided with a second liquid inlet channel communicating with the second storage bag, the second liquid inlet channel includes a second liquid inlet port formed in the second branch tube body; and

[0022] The second cap is connected to one end of the second branch pipe body away from the main pipe body, and the second cap covers the second liquid inlet.

[0023] Optionally, the radiotherapy and chemotherapy drug delivery device further includes a guide needle, which can be inserted into the second liquid inlet channel and the radiotherapy fluid channel, and can extend out of the second end of the main body.

[0024] Compared with related technologies, the radiotherapy and chemotherapy drug delivery device of the present invention has the following advantages: by providing mutually unconnected radiotherapy and chemotherapy fluid channels within the main body, radiotherapy or chemotherapy can be performed independently, or radiotherapy and chemotherapy can be performed in combination. After the device is placed, precise and effective radiotherapy and chemotherapy can be performed at the tumor location, eliminating the need for repeated surgeries, reducing the risk of brain tissue damage and infection, and prolonging the patient's lifespan. Moreover, the main body and the first storage capsule are relatively small, thus minimizing damage to the patient's brain tissue. The first and second liquid inlet components are disposed externally, making operation convenient, and the injection operation is not restricted by time or space. BRIEF DESCRIPTION OF THE DRAWINGS

[0025] In order to more clearly illustrate the technical solutions in the embodiments of the present invention or related technologies, the following briefly introduces the drawings required for use in the embodiments or related technical descriptions. Obviously, the drawings described below are only some embodiments of the present invention. For those skilled in the art, other drawings can be obtained based on these drawings without creative work.

[0026] Figure 1 This is a cross-sectional view of a radiotherapy and chemotherapy drug delivery device provided by one embodiment of the present invention;

[0027] Figure 2 yes Figure 1 Sectional view of detail A;

[0028] Figure 3 yes Figure 1 Sectional view of detail B;

[0029] Figure 4 This is a cross-sectional view of a radiotherapy and chemotherapy drug delivery device provided by another embodiment of the present invention;

[0030] Figure 5 It is a structural schematic diagram of the guide needle in the embodiment of the present utility model.

[0031] In the accompanying drawings, each reference numeral represents:

[0032] 1. Main body; 11. Radiotherapy fluid channel; 12. Chemotherapy fluid channel; 13. First liquid outlet; 14. Second liquid outlet; 2. Radiotherapy assembly; 21. First storage capsule; 22. First branch tube; 221. First liquid inlet; 2211. First liquid inlet; 2212. First liquid outlet; 23. First cover cap; 3. Chemotherapy assembly; 31. Second storage capsule; 32. Second branch tube; 321. Second liquid inlet; 3211. Second liquid inlet; 3212. Second liquid outlet; 322. Third liquid outlet; 33. Second cover cap; 4. Guide needle; 41. Grip. DETAILED DESCRIPTION

[0033] The following describes in detail embodiments of the present invention, examples of which are shown in the accompanying drawings, wherein the same or similar reference numerals throughout represent the same or similar elements or elements having the same or similar functions. The embodiments described below with reference to the accompanying drawings are exemplary and are intended to be used to explain the present invention, and should not be construed as limiting the present invention. All other embodiments obtained by persons of ordinary skill in the art based on the embodiments of the present invention without creative effort are within the scope of protection of the present invention.

[0034] In the description of the present invention, it should be understood that the terms "center", "longitudinal", "lateral", "length", "width", "thickness", "up", "down", "front", "back", "left", "right", "vertical", "horizontal", "top", "bottom", "inside", "outside", "clockwise", "counterclockwise", "axial", "circumferential", "radial", etc., indicating the orientation or position relationship, are based on the orientation or position relationship shown in the accompanying drawings, and are only for the convenience of describing the present invention and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, be constructed and operated in a specific orientation, and therefore cannot be understood as a limitation on the present invention.

[0035] Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance or implicitly specifying the number of the technical features being referred to. Thus, a feature specified as "first" or "second" may explicitly or implicitly include one or more of such features. In the description of this utility model, "plurality" means two or more, unless otherwise specifically defined.

[0036] Example:

[0037] See also Figures 1 to 5The embodiment of the present invention provides a radiotherapy and chemotherapy drug delivery device, comprising a main body 1, a radiotherapy component 2 and a chemotherapy component 3. The main body 1 is provided with a radiotherapy fluid channel 11 and a chemotherapy fluid channel 12 which are not connected to each other. The main body 1 is provided with a first end and a second end which are relatively distributed along its length direction, wherein the first end is the proximal end of the main body 1 and the second end is the distal end of the main body 1. After the device is placed, the first end is located outside the body and the second end is located at the tumor resection position inside the body. The radiotherapy component 2 includes a first liquid inlet component and a first storage capsule 21. The first liquid inlet component is provided at the first end of the main body 1 and is connected to the radiotherapy fluid channel 11. The first storage capsule 21 is provided at the second end of the main body 1 and is connected to the radiotherapy fluid channel 11. The radiotherapy fluid first passes through the first liquid inlet component. The injection flows into the radiotherapy fluid channel 11, and then flows into the first storage capsule 21 to be stored. The radiotherapy fluid performs close-range irradiation treatment on the tumor tissue; the chemotherapy component 3 includes a second liquid inlet component, which is arranged at the first end of the main body 1 and is connected to the chemotherapy fluid channel 12. The second end of the main body 1 is provided with a first liquid outlet 13 connected to the chemotherapy fluid channel 12. The first liquid outlet 13 is exposed on the outer surface of the main body 1 and is staggered with the first storage capsule 21. The chemotherapy fluid is injected into the chemotherapy fluid channel 12 through the second liquid inlet component, and then flows into the tumor tissue through the first liquid outlet 13 for chemical drug treatment.

[0038] By providing mutually unconnected radiotherapy fluid channels 11 and chemotherapy fluid channels 12 within the main body 1, radiotherapy or chemotherapy can be performed independently, or both can be performed in tandem. Once the device is in place, precise and effective radiotherapy and chemotherapy can be performed at the tumor site, eliminating the need for repeated surgeries, reducing the risk of brain damage and infection, and prolonging the patient's lifespan. Furthermore, the main body 1 and first storage capsule 21 are relatively small, minimizing damage to the patient's brain tissue. The first and second liquid inlet assemblies are externally located, making operation convenient and the injection process unrestricted by time and space.

[0039] It should be noted that since the first liquid outlet 13 is exposed on the outer surface of the main body 1 and is staggered with the first storage capsule 21, the chemotherapy liquid can be prevented from flowing into the first storage capsule 21 through the first liquid outlet 13, thereby ensuring that the chemotherapy liquid can flow into the tumor tissue through the first liquid outlet 13.

[0040] See also Figure 1 、 Figure 3 and Figure 4The lengths of the radiotherapy fluid channel 11 and the chemotherapy fluid channel 12 both extend along the axial direction of the main body 1, and the radiotherapy fluid channel 11 and the chemotherapy fluid channel 12 are parallel to each other, ensuring that the radiotherapy fluid channel 11 and the chemotherapy fluid channel 12 are not connected to each other. If practical needs are met, the radiotherapy fluid channel 11 and the chemotherapy fluid channel 12 can be arranged adjacent to each other, which is beneficial for reducing the volume of the main body 1.

[0041] See also Figure 1 、 Figure 3 and Figure 4 The second end of the main body 1 is provided with a second liquid outlet 14, which connects the radiotherapy fluid channel 11 and the first storage capsule 21. The radiotherapy fluid in the radiotherapy fluid channel 11 can flow into the first storage capsule 21 through the second liquid outlet 14, thereby performing brachytherapy on the tumor tissue in the first storage capsule 21. The second liquid outlet 14 is exposed on the outer surface of the main body 1, and the first storage capsule 21 covers the second liquid outlet 14. Multiple second liquid outlets 14 can be provided, and the multiple second liquid outlets 14 are evenly distributed on the outer surface of the main body 1.

[0042] See also Figure 1 、 Figure 2 and Figure 4 The first liquid inlet assembly includes a first branch tube 22 and a first cap 23. The first branch tube 22 is connected to the first end of the main tube 1. The first branch tube 22 is provided with a first liquid inlet channel 221 that communicates with the radiotherapy fluid channel 11. The first liquid inlet channel 221 includes a first liquid inlet port 2211 formed therein. Radiotherapy fluid is injected into the first liquid inlet channel 221 through the first liquid inlet port 2211. The first cap 23 is connected to the end of the first branch tube 22 away from the main tube 1. The first cap 23 covers the first liquid inlet port 2211 to provide sealing protection for the first liquid inlet channel 221. Among them, the first branch tube body 22 is arranged at the fork position of the main body 1, and the first cap 23 and the first branch tube body 22 are flexibly connected, which facilitates the first cap 23 to cover the first liquid inlet 2211 or detach from the first liquid inlet 2211; the first liquid inlet channel 221 also includes a first liquid outlet 2212 formed with the first branch tube body 22, and the first liquid outlet 2212 and the first liquid inlet 2211 are respectively located at the two ends of the first branch tube body 22, and the first liquid outlet 2212 is connected to the radiotherapy fluid channel 11.

[0043] During radiotherapy, the first cap 23 is opened and radiotherapy fluid is injected into the first liquid inlet channel 221 through the first liquid inlet 2211. The radiotherapy fluid in the first liquid inlet channel 221 flows into the radiotherapy fluid channel 11 through the first liquid outlet 2212, and then flows into the first storage capsule 21 through the second liquid outlet 14. The radiotherapy fluid is stored in the first storage capsule 21 and performs brachytherapy on the tumor tissue. It should be understood that the first cap 23, the first liquid inlet 2211, the first liquid inlet channel 221, the first liquid outlet 2212, the radiotherapy fluid channel 11, the second liquid outlet 14, and the first storage capsule 21 form a completely enclosed channel, thereby preventing adverse effects caused by leakage of the radiotherapy fluid.

[0044] See also Figure 1 、 Figure 3 and Figure 4 The second end of the main body 1 extends outside the first storage capsule 21. The first liquid outlet 13 is provided in the portion of the main body 1 extending outside the first storage capsule 21. This prevents the chemotherapy fluid from flowing into the first storage capsule 21 through the first liquid outlet 13, ensuring that the chemotherapy fluid can flow into the tumor tissue through the first liquid outlet 13. If necessary, the length of the radiotherapy fluid channel 11 at the second end of the main body 1 can be longer than the length of the chemotherapy fluid channel 12 at the second end of the main body 1.

[0045] See also Figure 1 and Figure 3 In some embodiments, the second liquid inlet assembly includes a second branch tube 32 and a second cap 33. The second branch tube 32 is connected to the first end of the main tube 1. The second branch tube 32 is provided with a second liquid inlet channel 321 that communicates with the radiotherapy fluid channel 11. The second liquid inlet channel 321 includes a second liquid inlet port 3211 formed in the second branch tube 32. The chemotherapy fluid is injected into the second liquid inlet channel 321 through the second liquid inlet port 3211. The second cap 33 is connected to the end of the second branch tube 32 away from the main tube 1. The second cap 33 covers the second liquid inlet port 3211 to provide sealing protection for the second liquid inlet channel 321. Among them, the first branch tube body 22 can be set integrally with the main body 1 to simplify the structure of the device; the length of the radiotherapy fluid channel 11 at the first end of the main body 1 is shorter than the length of the chemotherapy fluid channel 12 at the first end of the main body 1, and the second cap 33 is flexibly connected to the second branch tube body 32, which facilitates the second cap 33 to cover the second liquid inlet 3211 or detach from the second liquid inlet 3211.

[0046] See also Figure 1 and Figure 2The second liquid inlet assembly further includes a second storage capsule 31, which is connected to the first end of the main body 1 and the second branch tube 32, respectively. The second storage capsule 31 is connected to the chemotherapy fluid channel 12 and the second liquid inlet channel 321, respectively. The second storage capsule 31 can temporarily store the chemotherapy fluid, allowing the chemotherapy fluid to slowly flow out of the first liquid outlet 13. A third liquid outlet 322 is provided on the outside of the second branch tube 32. Multiple third liquid outlets 322 can be provided. The third liquid outlets 322 connect the second liquid inlet channel 321 and the second storage capsule 31, respectively, so that the chemotherapy fluid in the second liquid inlet channel 321 flows through the third liquid outlet 322 into the second storage capsule 31.

[0047] It should be understood that the second storage capsule 31 is connected to the first end of the main body 1 and the second branch tube 32 respectively, and the first branch tube 22 and the main body 1 are integrally arranged, which can improve the connection firmness of the second storage capsule 31.

[0048] During chemotherapy, the second cap 33 is opened and chemotherapy fluid is injected into the second liquid inlet channel 321 through the second liquid inlet 3211. The radiotherapy fluid flows from the second liquid inlet channel 321 through the third liquid outlet 322 into the second storage capsule 31 and is temporarily stored in the second storage capsule 31. The chemotherapy fluid in the second storage capsule 31 flows into the chemotherapy fluid channel 12 and then flows into the tumor tissue through the first liquid outlet 13, thereby providing chemotherapy treatment to the tumor tissue. It should be understood that the second cap 33, the second liquid inlet 3211, the second liquid inlet channel 321, the third liquid outlet 322, the second storage capsule 31, the chemotherapy fluid channel 12, and the first liquid outlet 13 form a semi-enclosed channel to ensure that the chemotherapy fluid can flow into the tumor tissue.

[0049] See also Figure 4In other embodiments, the second liquid inlet assembly includes a second storage capsule 31, a second branch tube body 32, and a second cap 33. The second storage capsule 31 is connected to the first end of the main body 1, and the second storage capsule 31 is communicated with the chemotherapy liquid channel 12; the second branch tube body 32 is connected to the second storage capsule 31, and the second branch tube body 32 is provided with a second liquid inlet channel 321 communicated with the second storage capsule 31, and the second liquid inlet channel 321 includes a second liquid inlet 3211 formed in the second branch tube body 32; wherein the second branch tube body 32 and the main body 1 are separated, and the second liquid inlet channel 321 also includes a second liquid inlet port 3211 formed in the second branch tube body 32. Two liquid outlets 3212, the second liquid outlet 3212 and the second liquid inlet 3211 are respectively located at the two ends of the second branch tube body 32, and the second liquid outlet 3212 is connected to the second storage capsule 31, so there is no need to set a liquid outlet hole on the second branch tube body 32 to connect with the second storage capsule 31, which facilitates the chemotherapy liquid to flow from the second liquid inlet channel 321 into the second storage capsule 31; the second cap 33 is connected to the end of the second branch tube body 32 away from the main body 1, and the second cap 33 covers the second liquid inlet 3211.

[0050] See also Figure 5 The chemoradiotherapy device also includes a guide needle 4, which can be inserted into the second liquid inlet channel 321 and the radiotherapy liquid channel 11 and extend beyond the second end of the main body 1. Guided and supported by the guide needle 4, the main body 1 can be precisely placed at the tumor location and can be removed before treatment. A grip 41 is provided at one end of the guide needle 4 to facilitate insertion and removal.

[0051] In some embodiments, the main body 1, the first branch tube 22, the second branch tube 32, the first storage bag 21 and the second storage bag 31 can be made of elastic materials such as silicone, and the first cap 23 and the second cap 33 can be made of elastic materials such as plastic and silicone.

[0052] The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention. Any modifications, equivalent replacements and improvements made within the spirit and principles of the present invention should be included in the scope of protection of the present invention.

Claims

1. A radiotherapy and chemotherapy drug delivery device, characterized in that: include: a main body, in which a radiotherapy fluid channel and a chemotherapy fluid channel are formed, which are not connected to each other, and the main body is provided with a first end and a second end which are oppositely distributed along the length direction thereof; a radiotherapy assembly comprising a first liquid inlet assembly and a first storage capsule, wherein the first liquid inlet assembly is disposed at a first end of the main body and communicates with the radiotherapy fluid channel, and the first storage capsule is disposed at a second end of the main body and communicates with the radiotherapy fluid channel; and The chemotherapy component includes a second liquid inlet component, which is arranged at the first end of the main body and is connected to the chemotherapy liquid channel. The second end of the main body is provided with a first liquid outlet hole connected to the chemotherapy liquid channel. The first liquid outlet hole is exposed on the outer surface of the main body and is staggered with the first storage bag.

2. The radiotherapy and chemotherapy drug delivery device according to claim 1, characterized in that: The lengths of the radiotherapy fluid channel and the chemotherapy fluid channel both extend along the axial direction of the main body, and the radiotherapy fluid channel and the chemotherapy fluid channel are parallel to each other.

3. The radiotherapy and chemotherapy drug delivery device according to claim 1, characterized in that: A second liquid outlet is provided at the second end of the main body, and the second liquid outlet is connected to the radiotherapy fluid channel and the first storage bag respectively.

4. The radiotherapy and chemotherapy drug delivery device according to claim 3, characterized in that: The second liquid outlet is exposed on the outer surface of the main body, and the first storage bag covers the second liquid outlet.

5. The radiotherapy and chemotherapy drug delivery device according to claim 1, characterized in that: The first liquid inlet component comprises: a first branch tube body connected to a first end of the main tube body, the first branch tube body being provided with a first liquid inlet channel communicating with the radiotherapy fluid channel, the first liquid inlet channel including a first liquid inlet port formed in the first branch tube body; and The first cap is connected to one end of the first branch pipe body away from the main pipe body, and the first cap covers the first liquid inlet.

6. The radiotherapy and chemotherapy drug delivery device according to claim 1, characterized in that: The second end of the main body extends out of the first storage bag, and the first liquid outlet is provided at the portion of the main body extending out of the first storage bag.

7. The radiotherapy and chemotherapy drug delivery device according to claim 1, characterized in that: The second liquid inlet component comprises: a second branch tube body connected to the first end of the main tube body, the second branch tube body being provided with a second liquid inlet channel communicating with the radiotherapy fluid channel, the second liquid inlet channel including a second liquid inlet port formed in the second branch tube body; and The second cap is connected to one end of the second branch pipe body away from the main pipe body, and the second cap covers the second liquid inlet.

8. The radiotherapy and chemotherapy drug delivery device according to claim 7, characterized in that: The second liquid inlet component further includes a second storage bag, which is respectively connected to the first end of the main pipe body and the second branch pipe body, and the second storage bag is respectively connected to the chemotherapy fluid channel and the second liquid inlet channel.

9. The radiotherapy and chemotherapy drug delivery device according to claim 1, characterized in that: The second liquid inlet component comprises: a second storage bag connected to the first end of the main body, and the second storage bag is in communication with the chemotherapy fluid channel; A second branch tube body is connected to the second storage bag, the second branch tube body is provided with a second liquid inlet channel communicating with the second storage bag, the second liquid inlet channel includes a second liquid inlet port formed in the second branch tube body; and The second cap is connected to one end of the second branch pipe body away from the main pipe body, and the second cap covers the second liquid inlet.

10. The radiotherapy and chemotherapy drug delivery device according to claim 7 or 9, characterized in that: The radiotherapy and chemotherapy drug delivery device further includes an introducer needle, which can be inserted into the second liquid inlet channel and the radiotherapy fluid channel, and can extend out of the second end of the main body.

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