Isolator injection nozzle

By designing the isolator injection nozzle and utilizing the annularly distributed pore structure to improve airflow diffusion, the problem of incomplete purification from below the HEPA filter to above the flow equalization membrane in the isolator is solved, thus enhancing the isolator's aseptic control capability.

CN223475266UActive Publication Date: 2025-10-28TOT BIOPHARM CO LTD
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Patent Information

Application Number
CN202422647442.7
Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2024-10-31
Publication Date
2025-10-28
Estimated Expiration
2034-10-31

AI Technical Summary

Technical Problem

In existing isolators, the purification effect from the bottom of the high-efficiency filter to the top of the flow-equalizing membrane is poor, resulting in incomplete purification of the isolator and increasing the risk of product sterility.

Method used

Design an isolator injection nozzle. The nozzle body is a rotating structure with an internal air chamber. The assembly plate divides the nozzle body into upper and lower air outlet sections, and sets annularly distributed air holes on the air outlet sections to increase the air outlet path and improve the airflow diffusion capability.

Benefits of technology

The purification capacity in the isolator is improved, the purification effect from the area above the equalizing membrane to the area below the high-efficiency filter is ensured, and the risk of product sterility is reduced.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an isolator injection nozzle, and relates to the field of isolator disinfection. The isolator injection nozzle comprises a nozzle body and an assembly disc, an air cavity is formed in the nozzle body, and the nozzle body is divided into an upper air outlet section and a lower air outlet section by the assembly disc; a first air hole, a second air hole and a third air hole which penetrate through the upper air outlet section and are communicated with the air cavity are formed in the upper air outlet section. The multiple first air holes, the multiple second air holes and the multiple third air holes are used for increasing the air outlet path of the upper air outlet section so as to improve the air outlet circulation amount of the upper air outlet section, and the first air holes, the second air holes and the third air holes which are annularly distributed are beneficial for airflow guided out to be distributed towards the surrounding environment and circulate in a balanced mode. The diffusivity of purified gas in the isolator is improved, the distribution effect of vaporized hydrogen peroxide from the position above the flow equalizing membrane to the position below the efficient filter is improved, and the purification effect is guaranteed. According to the utility model, the purification capacity in the isolator can be enhanced, and the sterile control of products in the isolator is improved.
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Description

Technical Field

[0001] This utility model relates to the field of isolator disinfection, specifically to an isolator injection nozzle. Background Technology

[0002] Vaporized hydrogen peroxide (VHP) sterilization technology utilizes the advantage that hydrogen peroxide in its gaseous state is more effective at killing sporozoites than in its liquid state at room temperature. It generates free hydroxyl groups that attack cellular components, including lipids, proteins, and DNA, achieving complete sterilization. It is commonly used for sterilizing enclosed spaces such as isolation rooms and isolators. Vaporized hydrogen peroxide (VHP) sterilization is dry, rapid, non-toxic, leaves no residue, and has good material compatibility.

[0003] Currently, VHP (Vacuum Hydrogen Peroxide) is a commonly used method for space and surface purification within isolators. Specifically, gaseous hydrogen peroxide is continuously introduced into the isolator to maintain a certain concentration and time, thereby achieving space and surface purification. The isolator chamber is divided into upper and lower chambers by a high-efficiency particulate filter (HEPA filter). The production work area is located in the lower chamber, which is purified by the VHP. To overcome the differences in airflow velocity caused by variations in HEPA filters, a flow equalization membrane is usually placed below the HEPA filter to stabilize the airflow. However, because the flow equalization membrane itself also affects the diffusion of hydrogen peroxide, in related technologies, most of the hydrogen peroxide gas output from the injection nozzle tends to remain below the flow equalization membrane, resulting in poor purification from above the flow equalization membrane to below the HEPA filter. This leads to incomplete purification by the isolator and significantly increases the risk of product sterility issues. Utility Model Content

[0004] To address the technical problems mentioned above, this utility model provides an isolator injection nozzle, comprising:

[0005] The nozzle body is configured as a rotating structure, and an air chamber is provided inside the nozzle body, which extends along the axial direction of the nozzle body;

[0006] An assembly plate is fitted and fixed to the outer periphery of the nozzle body, and the assembly plate divides the nozzle body into an upper air outlet section and a lower air outlet section; each air outlet section is provided with an air hole structure.

[0007] The upper air outlet section is provided with a first air hole and a second air hole that pass through the upper air outlet section and communicate with the air cavity. The first air hole and the second air hole are spaced apart. The first air hole is distributed in a ring on the upper air outlet section, and the second air hole is distributed in a ring on the upper air outlet section.

[0008] As a preferred technical solution, the upper air outlet section is configured as a cylindrical structure, the lower air outlet section is configured as a cylindrical structure, and the inner cavity of the upper air outlet section and the inner cavity of the lower air outlet section together constitute the air chamber.

[0009] As a preferred technical solution, at least one set of third air holes is also constructed on the upper air outlet section. The third air holes pass through the upper air outlet section and are connected to the air cavity. The set of third air holes are distributed in a ring on the upper air outlet section. The third air holes are spaced apart in the direction away from the second air hole and away from the first air hole.

[0010] As a preferred technical solution, the first air hole, the second air hole, and the third air hole are arranged at equal intervals in a direction parallel to the upper air outlet section; and / or

[0011] The first vent has six vents; the second vent has six vents; and the third vent has six vents.

[0012] As a preferred technical solution, the first vent is configured as a cylindrical vent; the central angle formed by the central axes of two adjacent first vents is set to 20 degrees; and / or

[0013] The second vent is configured as a cylindrical vent, and the central angle between the central axes of two adjacent second vents is set to 20 degrees; and / or

[0014] The third vent is configured as a cylindrical vent, and the central angle between the central axes of two adjacent third vents is set to 20 degrees.

[0015] As a preferred technical solution, the lower air outlet section is provided with a fourth air hole that passes through the upper air outlet section and communicates with the air cavity. The fourth air hole is located in the outer peripheral region of the lower air outlet section away from the upper air outlet section, and the fourth air hole is distributed in a ring on the lower air outlet section.

[0016] As a preferred technical solution, the nozzle body includes an interface portion, which is fixedly connected to the upper air outlet section. The interface portion is recessed on the side opposite to the upper air outlet section, and a connecting hole communicating with the air chamber is provided on the interface portion.

[0017] As a preferred technical solution, the nozzle body further includes a frustum portion, which is disposed at the end of the lower air outlet section away from the upper air outlet section, and the frustum portion and the lower air outlet section are coaxially arranged; in the direction of the lower air outlet section away from the upper air outlet section, the radial dimension of the frustum portion is set to decrease.

[0018] The frustum portion has a gas distribution chamber that connects to the gas chamber; the frustum portion is provided with a fifth gas hole and a sixth gas hole, the fifth gas hole is distributed in a ring on the frustum portion and is connected to the gas distribution chamber of the frustum portion, the sixth gas hole extends along the central axis of the frustum portion and is connected to the gas distribution chamber of the frustum portion.

[0019] As a preferred technical solution, the assembly plate is provided with a plurality of assembly holes, the assembly holes are configured as blind holes, and the assembly holes are arranged on the end face of the assembly plate near the upper air outlet section.

[0020] The assembly disk is configured as a rotating body structure, and the assembly holes are arranged in a ring on the assembly disk.

[0021] As a preferred technical solution, the nozzle body and the assembly plate are integrally formed; or

[0022] An assembly cavity is provided on the assembly plate, and the nozzle body is installed in the assembly cavity.

[0023] The technical solution provided by this utility model has the following advantages:

[0024] The isolator injection nozzle provided by this utility model includes a nozzle body and an assembly plate. The nozzle body is configured as a rotating body structure, and an air chamber is provided inside the nozzle body, extending along the axial direction of the nozzle body. The assembly plate is sleeved and fixed on the outer periphery of the nozzle body, dividing the nozzle body into an upper air outlet section and a lower air outlet section. An air hole structure is provided on either air outlet section. The upper air outlet section is constructed with a first air hole and a second air hole that pass through the upper air outlet section and communicate with the air chamber. The first air hole and the second air hole are arranged alternately, with the first air hole and the second air hole being distributed in a ring on the upper air outlet section.

[0025] This isolator injection nozzle has an air chamber inside the nozzle body connected to an external drive air supply device. An assembly plate is fitted and fixed to the outer periphery of the nozzle body, providing a fixed base. The upper air outlet section of the nozzle body is equipped with annularly arranged first and second air holes. Multiple first and second air holes increase the air outlet path of the upper air outlet section, thereby improving the airflow. The annular distribution of the first and second air holes also facilitates a balanced distribution of the outgoing airflow towards the surrounding environment. This design effectively improves the diffusion capacity of the purified gas within the isolator. Therefore, when a flow equalization membrane is installed inside the isolator, it reduces the obstruction of the flow equalization membrane on the purified gas distributed from above the flow equalization membrane to below the high-efficiency filter, ensuring the purification effect in this area. The isolator injection nozzle provided by this invention enhances the purification capacity within the isolator and improves the aseptic control of products within the isolator. Attached Figure Description

[0026] To more clearly illustrate the specific embodiments of this utility model or the technical solutions in the prior art, the drawings used in the description of the specific embodiments or the prior art will be briefly introduced below. Obviously, the drawings described below are some embodiments of this utility model. For those skilled in the art, other drawings can be obtained from these drawings without creative effort.

[0027] Figure 1 A schematic diagram of the structure of the isolator injection nozzle provided by this utility model;

[0028] Figure 2 A three-dimensional schematic diagram of the isolator injection nozzle provided by this utility model from a perspective view;

[0029] Figure 3 A side view of the injector nozzle of the isolator provided by this utility model;

[0030] Figure 4 A top-view structural schematic diagram of the isolator injection nozzle provided by this utility model;

[0031] Figure 5 A top view structural schematic diagram of the isolator injection nozzle provided by this utility model;

[0032] Explanation of reference numerals in the attached figures:

[0033] 1- Nozzle body; 11- Upper air outlet section; 111- First air hole; 112- Second air hole; 113- Third air hole; 12- Lower air outlet section; 121- Fourth air hole; 122- Fifth air hole; 123- Sixth air hole; 13- Interface section; 131- Connecting groove; 132- Connecting hole; 14- Frustum section;

[0034] 2-Assembly plate; 21-Assembly hole; 22-Assembly cavity. Detailed Implementation

[0035] The technical solution of this utility model will now be clearly and completely described with reference to the accompanying drawings. Obviously, the described embodiments are only some, not all, of the embodiments of this utility model. Based on the embodiments of this utility model, all other embodiments obtained by those skilled in the art without creative effort are within the scope of protection of this utility model.

[0036] In the description of this utility model, it should be noted that the terms "center," "upper," "lower," "left," "right," "vertical," "horizontal," "inner," and "outer," etc., indicating the orientation or positional relationship, are based on the orientation or positional relationship shown in the accompanying drawings and are only for the convenience of describing this utility model and simplifying the description, and do not indicate or imply that the device or element referred to must have a specific orientation, or be constructed and operated in a specific orientation, and therefore should not be construed as a limitation of this utility model. Furthermore, the terms "first" and "second" are used for descriptive purposes only and should not be construed as indicating or implying relative importance.

[0037] In the description of this utility model, it should be noted that, unless otherwise explicitly specified and limited, the terms "installation," "connection," and "joining" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection or an electrical connection; they can refer to a direct connection or an indirect connection through an intermediate medium; and they can refer to the internal connection of two components. Those skilled in the art can understand the specific meaning of the above terms in this utility model based on the specific circumstances.

[0038] Furthermore, the technical features involved in the different embodiments of this utility model described below can be combined with each other as long as they do not conflict with each other.

[0039] Example

[0040] This embodiment provides an isolator injection nozzle, see [link]. Figures 1 to 5 It includes a nozzle body 1 and an assembly plate 2. The air chamber inside the nozzle body 1 is connected to an external air supply device for purifying gas. The assembly plate 2 is sleeved and fixed on the outer periphery of the nozzle body 1 and can be used to provide a fixed foundation. The nozzle body 1 is configured as a rotating body structure. An air chamber is provided inside the nozzle body 1 and extends along the axial direction of the nozzle body 1. The assembly plate 2 divides the nozzle body 1 into an upper air outlet section 11 and a lower air outlet section 12.

[0041] In this embodiment, air outlet section 11 and lower air outlet section 12 are respectively provided with air hole structures.

[0042] See Figure 2 and Figure 3 For the air outlet section 11, the upper air outlet section 11 is provided with a first air hole 111 and a second air hole 112 that pass through the upper air outlet section 11 and communicate with the air cavity. The first air hole 111 and the second air hole 112 are arranged alternately. The first air hole 111 is distributed in a ring on the upper air outlet section 11, and the second air hole 112 is distributed in a ring on the upper air outlet section 11.

[0043] The isolator injection nozzle provided in this embodiment has an annular arrangement of first air holes 111 and second air holes 112 on the upper air outlet section 11 of the nozzle body 1. The multiple first air holes 111 and multiple second air holes 112 increase the air outlet path of the upper air outlet section 11, thereby increasing the air outlet flow rate of the upper air outlet section 11. The annular arrangement of the first air holes 111 and second air holes 112 facilitates the balanced distribution of the outgoing airflow towards the surrounding environment. This arrangement can effectively improve the diffusion capacity of the purified gas in the isolator. Thus, when a flow equalization membrane is set in the isolator, the obstruction effect of the flow equalization membrane on the purified gas distributed from above the flow equalization membrane to below the HEPA filter is reduced, ensuring the purification effect in this area. This can solve the defect that the VHP of the isolator is difficult to completely purify in the space below the HEPA filter to above the flow equalization membrane and on the surface of the flow equalization membrane.

[0044] The isolator injection nozzle provided by this utility model can enhance the purification capacity within the isolator and improve the aseptic control of the products within the isolator.

[0045] In a specific implementation, the upper air outlet section 11 is configured as a cylindrical structure, the lower air outlet section 12 is configured as a cylindrical structure, and the inner cavity of the upper air outlet section 11 and the inner cavity of the lower air outlet section 12 together constitute an air chamber.

[0046] For a preferred embodiment, see Figure 2 and Figure 3 At least one set of third air holes 113 are also constructed on the upper air outlet section 11. The third air holes 113 pass through the upper air outlet section 11 and are connected to the air cavity. A set of third air holes 113 are distributed in a ring on the upper air outlet section 11. The third air holes 113 are spaced apart in the direction away from the second air hole 112 and away from the first air hole 111.

[0047] In an exemplary embodiment, the upper air outlet section 11 is provided with a set of first air holes 111, a set of second air holes 112 and a set of third air holes arranged in a ring.

[0048] In one specific embodiment, six first vents 111 are provided; six second vents 112 are provided; and six third vents 113 are provided.

[0049] In a specific implementation, the first air hole 111, the second air hole 112, and the third air hole 113 are arranged at equal intervals in the axial direction parallel to the upper air outlet section 11.

[0050] Of course, in other embodiments, the first air hole 111, the second air hole 112 and the third air hole 113 may be staggered and spaced apart along the axial direction parallel to the upper air outlet section 11.

[0051] As a further embodiment, the first vent 111 is configured as a cylindrical hole; the central angle formed by the central axes of two adjacent first vents 111 is set to 20 degrees. Similarly, the second vent 112 can be configured as a cylindrical hole, and the central angle formed by the central axes of two adjacent second vents 112 is set to 20 degrees. Similarly, the third vent 113 can be configured as a cylindrical hole, and the central angle formed by the central axes of two adjacent third vents 113 is set to 20 degrees.

[0052] For a specific implementation method, see Figure 2 and Figure 3 For the vent structure of the lower air outlet section 12, a fourth vent 121 is constructed on the lower air outlet section 12, which penetrates the upper air outlet section 11 and communicates with the air chamber. The fourth vent 121 is located in the outer peripheral region of the lower air outlet section 12 away from the upper air outlet section 11, and the fourth vent 121 is distributed in a ring on the lower air outlet section 12. The purified gas in the air chamber is led out and diffused towards the outside of the lower air outlet section 12 through the fourth vent 121.

[0053] In some implementations, see Figures 1 to 3 The nozzle body 1 includes an interface portion 13, which is fixedly connected to the upper air outlet section 11. A connecting groove 131 is recessed on the side of the interface portion 13 opposite to the upper air outlet section 11, and a connecting hole 132 communicating with the air chamber is provided through the interface portion 13. The interface portion 13 can be configured as a quick-connect chuck structure. The connecting groove 131 is used to engage with an external drive air supply device, and the connecting hole 132 is used to communicate with the air supply output port of the external drive air supply device to supply purified gas to the air chamber. This allows the purified gas to be discharged and circulated from the first air hole 111, the second air hole 112, and the third air hole 113 of the upper air outlet section 11, and the fourth air hole 121 of the lower air outlet section 12.

[0054] As a further implementation method, see Figures 2 to 4The nozzle body 1 also includes a frustum portion 14, which is located at the end of the lower air outlet section 12 away from the upper air outlet section 11. The frustum portion 14 and the lower air outlet section 12 are arranged coaxially. The radial dimension of the frustum portion 14 decreases in the direction away from the upper air outlet section 11 in the lower air outlet section 12. An air distribution chamber communicating with the air chamber is provided inside the frustum portion 14. A fifth air hole 122 and a sixth air hole 123 are constructed on the frustum portion 14. The fifth air hole 122 is distributed in a ring on the frustum portion 14 and is connected to the air distribution chamber of the frustum portion 14. The sixth air hole 123 extends along the central axis of the frustum portion 14 and is connected to the air distribution chamber of the frustum portion 14. The sixth vent 123 directs purified gas toward the lower part of the isolator to purify the space in that area. In a specific embodiment, the extension direction of the fifth vent 122 is inclined away from the central axis of the frustum portion 14. The extension direction of the fifth vent 122 can be inclined downward, so that the purified gas discharged from the fifth vent 122 and the purified gas discharged from the sixth vent 123 have different flow directions. This is beneficial to enhance the flow capacity of the purified gas toward the lower part of the isolator, thereby improving the purification effect on the lower part of the isolator.

[0055] For a specific implementation method, see Figure 2 The assembly plate 2 has several assembly holes 21, which are blind holes and are located on the end face of the assembly plate 2 near the upper air outlet section 11. The assembly plate 2 is a rotating body structure, and the assembly holes 21 are arranged in a ring on the assembly plate 2. The assembly holes 21 can be threaded holes, and the assembly plate 2 can be connected to the fixed frame of the external device by threaded fasteners. The number of assembly holes 21 can be four or more.

[0056] In a preferred embodiment, the nozzle body 1 and the assembly plate 2 are integrally formed, and the material of the nozzle body 1 and the assembly plate 2 can be stainless steel alloy. For other embodiments, see [link to other embodiments]. Figure 2 The assembly plate 2 has an assembly cavity 22, and the nozzle body 1 is installed in the assembly cavity 22; the assembly cavity 22 and the nozzle body 1 can be configured as an interference fit or a snap-fit.

[0057] The isolator injection nozzle provided in this embodiment, through optimized structure, increases the outlet path of the 11 air holes in the upper outlet section, which is beneficial to improving the diffusion capacity of the purified airflow. This addresses the deficiency of the isolator VHP in that the space below the HEPA filter and above the flow equalization membrane, as well as the surface of the flow equalization membrane, is difficult to completely purify. In specific operational tests, the injection nozzle passed the chemical indicator and biological indicator tests, and can well meet the purification requirements of the isolator.

[0058] In the above description, the purification gas is set as hydrogen peroxide or other disinfection gas.

[0059] Obviously, the above embodiments are merely illustrative examples for clear explanation and are not intended to limit the implementation. Those skilled in the art will recognize that other variations or modifications can be made based on the above description. It is neither necessary nor possible to exhaustively list all possible implementations here. However, obvious variations or modifications derived therefrom are still within the protection scope of this invention.

Claims

1. An isolator injection nozzle, characterized in that, include: The nozzle body (1) is configured as a rotating structure, and an air chamber is provided inside the nozzle body (1), which extends along the axial direction of the nozzle body (1). Assembly plate (2) is sleeved and fixed on the outer periphery of the nozzle body (1). The assembly plate (2) divides the nozzle body (1) into an upper air outlet section (11) and a lower air outlet section (12). Each air outlet section is provided with an air hole structure. The upper air outlet section (11) is provided with a first air hole (111) and a second air hole (112) that pass through the upper air outlet section (11) and communicate with the air cavity. The first air hole (111) and the second air hole (112) are spaced apart. The first air hole (111) is distributed in a ring on the upper air outlet section (11), and the second air hole (112) is distributed in a ring on the upper air outlet section (11).

2. The isolator injection nozzle according to claim 1, characterized in that, The upper air outlet section (11) is configured as a cylindrical structure, and the lower air outlet section (12) is configured as a cylindrical structure. The inner cavity of the upper air outlet section (11) and the inner cavity of the lower air outlet section (12) together constitute the air cavity.

3. The isolator injection nozzle according to claim 2, characterized in that, At least one set of third air holes (113) are also constructed on the upper air outlet section (11). The third air holes (113) pass through the upper air outlet section (11) and are connected to the air cavity. A set of third air holes (113) are distributed in a ring on the upper air outlet section (11). The third air holes (113) are spaced apart in the direction away from the second air hole (112) and the first air hole (111).

4. The isolator injection nozzle according to claim 3, characterized in that, In the axial direction parallel to the upper air outlet section (11), the first air hole (111), the second air hole (112), and the third air hole (113) are arranged at equal intervals in sequence; and / or The first air hole (111) has six holes; the second air hole (112) has six holes; and the third air hole (113) has six holes.

5. The isolator injection nozzle according to claim 3, characterized in that, The first vent (111) is configured as a cylindrical hole; the central angle formed by the central axes of two adjacent first vents (111) is configured as 20 degrees; and / or The second vent (112) is configured as a cylindrical hole, and the central angle formed by the central axes of two adjacent second vents (112) is set to 20 degrees; and / or The third vent (113) is configured as a cylindrical vent, and the central angle formed by the central axes of two adjacent third vents (113) is set to 20 degrees.

6. The isolator injection nozzle according to claim 2, characterized in that, The lower air outlet section (12) is provided with a fourth air hole (121) that passes through the upper air outlet section (11) and communicates with the air cavity. The fourth air hole (121) is located in the outer peripheral region of the lower air outlet section (12) away from the upper air outlet section (11), and the fourth air hole (121) is distributed in a ring on the lower air outlet section (12).

7. The isolator injection nozzle according to any one of claims 1-6, characterized in that, The nozzle body (1) includes an interface part (13), which is fixedly connected to the upper air outlet section (11). The interface part (13) has a connecting groove (131) recessed on the side away from the upper air outlet section (11), and a connecting hole (132) communicating with the air chamber is provided on the interface part (13).

8. The isolator injection nozzle according to any one of claims 1-6, characterized in that, The nozzle body (1) also includes a frustum portion (14), which is disposed at one end of the lower air outlet section (12) away from the upper air outlet section (11). The frustum portion (14) and the lower air outlet section (12) are coaxially arranged. In the direction away from the upper air outlet section (11) of the lower air outlet section (12), the radial dimension of the frustum portion (14) is reduced. The frustum portion (14) is provided with a gas distribution chamber that connects to the gas chamber; the frustum portion (14) is provided with a fifth gas hole (122) and a sixth gas hole (123), the fifth gas hole (122) is distributed in a ring on the frustum portion (14), the fifth gas hole (122) is connected to the gas distribution chamber of the frustum portion (14), the sixth gas hole (123) extends along the central axis of the frustum portion (14), and the sixth gas hole (123) is connected to the gas distribution chamber of the frustum portion (14).

9. The isolator injection nozzle according to any one of claims 1-6, characterized in that, The assembly plate (2) is provided with a plurality of assembly holes (21), the assembly holes (21) are configured as blind holes, and the assembly holes (21) are constructed on the end face of the assembly plate (2) near the upper air outlet section (11); The assembly disk (2) is configured as a rotating body structure, and the assembly hole (21) is arranged in a ring on the assembly disk (2).

10. The isolator injection nozzle according to any one of claims 1-6, characterized in that, The nozzle body (1) and the assembly plate (2) are integrally formed; or The assembly plate (2) is provided with an assembly cavity (22), and the nozzle body (1) is installed in the assembly cavity (22).