Reaction device for preparing antigen and antibody

Abstract

The utility model discloses a reaction device for preparing an antigen and an antibody, and relates to the field of antigen and antibody preparation. The device comprises a preparation reaction bin, a moving plate, a second mounting box and a sliding plate, a limiting ring is fixed to the top of the sliding plate, a containing container is arranged in the limiting ring, four sliding ways are fixed to the top of the outer side of the limiting ring in a circumferential array mode, and adjusting rods are arranged in the four sliding ways in a sliding mode; the bottoms of the four sets of adjusting rods are in clamped sliding with the sliding plate, the tops of the four sets of adjusting rods are in threaded connection with adjusting bolts, fastening supporting rods are fixed to the ends, close to the limiting ring, of the four sets of adjusting rods, the fastening supporting rods and the limiting ring are in clamped sliding, and the fastening supporting rods abut against the containing container in an attached mode. The device disclosed by the utility model can be well adapted to containing containers with different sizes, and the containing containers can be conveniently pushed out and replaced, so that the preparation reaction efficiency of antigens and antibodies is effectively improved.

Description

TECHNICAL FIELD

[0001] The utility model relates to the field of antigen antibody, concretely is a kind of reaction device for preparing antigen antibody. BACKGROUND

[0002] Antigen antibody is the core element of immune system, antigen can trigger body immune response, antibody can specifically recognize and combine antigen, and jointly maintain immune balance. They have important position in disease diagnosis, vaccine research and development etc. field, are the hotspot of scientific research. The interaction of antigen antibody is not only related to individual health, but also has far-reaching influence on public health safety, is the key scheme that human resists pathogen invasion, guarantees health. When antigen antibody is prepared, a variety of different antigen antibody mixings are needed, so as to observe subsequent mixing condition, however, the traditional antigen antibody preparation reaction device cannot be more quickly carried out multiple antigen antibody loading replacement, and using the same kind of loading container can also cause frequent cleaning of loading container, so as to cause waste of subsequent mixing time, reduce preparation productivity. SUMMARY

[0003] Therefore, the utility model provides a kind of reaction device for preparing antigen antibody, can be better adapted to different sizes of loading container and more conveniently push out and replace loading container, effectively improve the preparation reaction efficiency of antigen antibody.

[0004] To achieve the above object, the utility model provides the following technical scheme: a kind of reaction device for preparing antigen antibody, including preparation reaction bin, moving plate, second installation box and sliding plate, the top of preparation reaction bin is provided with moving plate, and the back bottom of preparation reaction bin is fixed with second installation box, and the inside of preparation reaction bin is installed with sliding plate, the top of sliding plate is fixed with limit ring, and the inside of limit ring is provided with loading container, the outside top of limit ring is fixed with four groups of slide in circumferential array, and the inside of four groups of slide is slidably provided with adjusting rod, the bottom of four groups of adjusting rod is all slidably engaged with sliding plate, and the top of four groups of adjusting rod is all threadedly connected with adjusting bolt, one end of four groups of adjusting rod near limit ring is all fixed with fastening support, and fastening support and limit ring are slidably engaged, and fastening support is attached to loading container and is tightly pressed.

[0005] By adopting the above technical scheme, preparation reaction bin is used as the safe operation place of antigen antibody preparation reaction, moving plate is used to stably drive the lower stirring blade to move, second installation box is used to provide protection function to the inside first tooth disc and second tooth disc, sliding plate is used to provide position moving function to the upper loading container.

[0006] The limiting ring is used for providing a clear placement position for the containing container, the slide is used for limiting the movement of the internal adjusting rod, the adjusting rod is used for driving the position adjustment of the fastening support rod, the adjusting bolt is used for fastening and limiting the adjusting rod and the slide, and the fastening support rod is used for supporting and fastening the containing container.

[0007] Further, the back of the second mounting box is provided with a second driving motor, and the output end of the second driving motor is provided with a first gear disc, and the first gear disc is rotationally engaged with the preparation reaction bin.

[0008] By adopting the above technical scheme, the second driving motor provided at the back of the second mounting box is used to provide rotation function for the first gear disc, and the first gear disc provided at the output end of the second driving motor is rotationally engaged with the preparation reaction bin, so that the power transmission of the first gear disc is more stable and efficient.

[0009] Further, the two sides of the first gear disc are engaged with two groups of second gear discs, and the two groups of second gear discs are rotationally engaged with the second mounting box, and the side of the two groups of second gear discs close to the preparation reaction bin is fixed with an adjusting screw rod, and the other end of the adjusting screw rod is rotationally connected with the preparation reaction bin.

[0010] By adopting the above technical scheme, the first gear disc is used to drive the synchronous rotation of the two groups of second gear discs, and the two groups of second gear discs are used to synchronously transmit the power of the first gear disc to the two groups of adjusting screw rods.

[0011] Further, the bottom of the sliding plate is fixed with a first sliding block, and is slidably engaged with the preparation reaction bin, and the bottom of the sliding plate and located on both sides of the first sliding block is fixed with two groups of second sliding blocks, and is respectively threadedly connected with the two groups of adjusting screw rods, and the two groups of second sliding blocks are slidably engaged with the preparation reaction bin.

[0012] By adopting the above technical scheme, the first sliding block fixed at the bottom of the sliding plate is slidably engaged with the preparation reaction bin, which ensures the stability and guidance of the sliding plate during movement, and the two groups of second sliding blocks fixed at both sides of the bottom of the sliding plate are respectively threadedly connected with the two groups of adjusting screw rods, and the two groups of second sliding blocks are also slidably engaged with the preparation reaction bin, so that the double sliding engagement design further enhances the stability and accuracy of the movement of the sliding plate.

[0013] Further, the surface of the preparation reaction bin is rotationally connected with a protective door through a torsion shaft, and the middle part of the protective door is provided with a transparent observation window.

[0014] By adopting the technical scheme, the surface of the preparation reaction bin is connected with the protective door through the torsion shaft, the protective door can be opened and closed flexibly, the operator can access and operate the inside of the preparation reaction bin conveniently, the middle part of the protective door is provided with the transparent observation window, and the operator can observe the inside of the preparation reaction bin in real time without opening the protective door.

[0015] Further, the four groups of support columns are fixed at the top of the four corners of the preparation reaction bin, and the top of the four groups of support columns is fixed with a top plate, and the middle part of the top plate is provided with a driving cylinder.

[0016] By adopting the technical scheme, the four groups of support columns fixed at the top of the four corners of the preparation reaction bin provide a stable support structure for the top plate, and the top plate fixed at the top of the four groups of support columns further enhances the overall rigidity of the equipment, and provides a stable mounting platform for the top components such as the driving cylinder.

[0017] Further, the moving plate is in sliding and limiting connection with the four groups of support columns, and the top of the moving plate is fixed with a first mounting box and is fixedly connected with the output end of the driving cylinder.

[0018] By adopting the technical scheme, the moving plate is in sliding and limiting connection with the four groups of support columns, which makes the moving plate move up and down stably on the support columns without deviation or rotation, the first mounting box fixed at the top of the moving plate is fixedly connected with the output end of the driving cylinder, and the driving cylinder can accurately control the lifting of the first mounting box and the moving plate when performing the telescopic action.

[0019] Further, the first driving motor is installed in the first mounting box, the output end of the first driving motor is provided with a stirring blade, and the stirring blade is arranged in corresponding relationship with the loading container in up-down direction.

[0020] By adopting the technical scheme, the first driving motor installed in the first mounting box provides power for the rotation of the stirring blade, and the stirring blade is arranged in corresponding relationship with the loading container in up-down direction, which ensures that the stirring blade can directly act on the mixed liquid in the loading container, and improves the stirring efficiency.

[0021] In summary, the utility model mainly has the following beneficial effects:

[0022] 1. The utility model discloses a sliding way, adjusting rod, adjusting bolt and fastening support rod are set up, and the thread fastening of adjusting rod and its fastening limit to sliding way are removed through the rotation adjusting bolt, so that adjusting rod can slip in the inside of sliding way and sliding plate, and then drive fastening support rod to move synchronously, make fastening support rod resist and fit the loading container in the inside of limit ring, then carry out the thread fastening of adjusting bolt and adjusting rod, so that the adjusting rod is fixed to prevent its drive fastening support rod to move, can through four fastening support rods outside limit ring to the loading container in its inside carry out quick dismouting to different size loading container fastening,

[0023] 2. The utility model discloses a first tooth disc, second tooth disc and adjusting screw rod are set up, through the control center starts second drive motor, makes its drive first tooth disc to rotate, and first tooth disc is driven to rotate through the meshing of two groups of second tooth discs on both sides, so that two groups of second tooth discs drive the adjusting screw rod on its one side to rotate, and two groups of adjusting screw rods are respectively connected through the thread connection of two groups of second sliding blocks at the bottom of sliding plate, so that two groups of second sliding blocks drive the sliding plate fixedly connected above to move in the inside of preparation reaction bin, can push the loading container above sliding plate to the outside of preparation reaction bin, convenient for operating personnel to dismouting replacement of loading container,

[0024] 3. In the utility model, the first sliding block at the bottom of the sliding plate is engaged with the preparation reaction bin and slides, so that the sliding plate has good support on the side close to the protective door during movement, preventing wear between the sliding plate and the preparation reaction bin during movement. BRIEF DESCRIPTION OF DRAWINGS

[0025] Figure 1 It is the overall front view structure schematic drawing of the utility model;

[0026] Figure 2 It is the overall side view structure schematic drawing of the utility model;

[0027] Figure 3 It is the overall structure schematic drawing of the sliding plate in the pushing-out state of the utility model;

[0028] Figure 4 It is the side view cross-sectional structure schematic drawing of the first tooth disc and the second tooth disc connection of the utility model;

[0029] Figure 5 It is the elevation cross-sectional structure schematic drawing of the adjusting screw rod and the second sliding block connection of the utility model;

[0030] Figure 6 It is the side view cross-sectional structure schematic drawing of the sliding way and the adjusting rod connection of the utility model.

[0031] In the figure: 1, preparation reaction bin; 2, protective door; 3, support column; 4, top plate; 5, drive cylinder; 6, moving plate; 7, first mounting box; 8, first drive motor; 9, stirring blade; 10, second mounting box; 11, second drive motor; 12, first tooth disc; 13, second tooth disc; 14, adjusting screw; 15, sliding plate; 16, limiting ring; 17, slide; 18, adjusting rod; 19, adjusting bolt; 20, fastening support rod; 21, loaded container; 22, first sliding block; 23, second sliding block. DETAILED DESCRIPTION

[0032] The technical solutions in the embodiments of the utility model will be clearly and completely described below with reference to the drawings in the embodiments of the utility model. The embodiments described below with reference to the drawings are exemplary and are used only for explaining the utility model and cannot be understood as limiting the utility model.

[0033] In the embodiment:

[0034] A reaction device for preparing antigen antibody, as shown in Figures 1-6 The upper portion of the preparation reaction bin 1 is provided with the moving plate 6, the back bottom of the preparation reaction bin 1 is fixed with the second mounting box 10, and the inside of the preparation reaction bin 1 is installed with the sliding plate 15, the top of the sliding plate 15 is fixed with the limiting ring 16, the inside of the limiting ring 16 is provided with the loaded container 21, the outside top of the limiting ring 16 is fixed with four groups of slide 17 in a circumferential array, the inside of the four groups of slide 17 is slidably provided with the adjusting rod 18, the bottom of the four groups of adjusting rod 18 is clamped and slid with the sliding plate 15, the top of the four groups of adjusting rod 18 is threadedly connected with the adjusting bolt 19, one end of the four groups of adjusting rod 18 close to the limiting ring 16 is fixed with the fastening support rod 20, the fastening support rod 20 is clamped and slid with the limiting ring 16, and the fastening support rod 20 is abuttingly and tightly connected with the loaded container 21;

[0035] The limiting ring 16 ensures the placement space of the loaded container 21, the clamped and sliding structure of the slide 17 and the adjusting rod 18 enables the operator to easily adjust the position of the fastening support rod 20, meanwhile, the thread connection of the adjusting bolt 19 makes the fixation of the fastening support rod 20 more reliable, effectively preventing the movement or loosening of the loaded container 21 during the reaction process, and the abutting and tight connection design of the fastening support rod 20 and the loaded container 21 ensures the stability of the loaded container 21 during the reaction process.

[0036] Referring to Figure 2 and Figure 4 The back of the second mounting box 10 is provided with the second drive motor 11, the output end of the second drive motor 11 is installed with the first tooth disc 12, and the first tooth disc 12 is rotationally clamped with the preparation reaction bin 1.

[0037] The second driving motor 11 serves as a power source of the first toothed disc 12, and can provide stable and controllable rotating power for the first toothed disc 12, which greatly improves the automation degree and operation convenience of the device. The first toothed disc 12 is rotationally connected with the preparation reaction bin 1, and the stability and safety of the first toothed disc 12 during operation are ensured.

[0038] Referring to Figure 2 , Figure 4 and Figure 5 , the two groups of second toothed discs 13 are meshed on the two sides of the first toothed disc 12, and are rotationally clamped with the second mounting box 10. The two groups of second toothed discs 13 are fixed with adjusting screws 14 on the side close to the preparation reaction bin 1, and the other end of the adjusting screw 14 is rotationally connected with the preparation reaction bin 1.

[0039] When the second driving motor 11 drives the first toothed disc 12 to rotate, the power can be smoothly transmitted to the two groups of second toothed discs 13, so as to ensure the stability and reliability of the two groups of second toothed discs 13. The two groups of second toothed discs 13 are fixed with adjusting screws 14 on the side close to the preparation reaction bin 1, and the other end of the adjusting screw 14 is rotationally connected with the preparation reaction bin 1, so that the adjusting screw 14 can be stably rotated under the driving of the second toothed disc 13, thereby further driving the two groups of second sliding blocks 23 at the bottom of the sliding plate 15 to move accurately inside the preparation reaction bin 1.

[0040] Referring to Figure 3 and Figure 5 , the first sliding block 22 is fixed at the bottom of the sliding plate 15 and is clamped and slid with the preparation reaction bin 1. The two groups of second sliding blocks 23 are fixed at the bottom of the sliding plate 15 and are respectively threadedly connected with the two groups of adjusting screws 14, and the two groups of second sliding blocks 23 are clamped and slid with the preparation reaction bin 1.

[0041] The clamping structure of the first sliding block 22 and the preparation reaction bin 1 provides a smooth sliding track for the sliding plate 15, effectively preventing the sliding plate 15 from deviating or shaking during movement, thereby ensuring the accuracy and reliability of the preparation of the antigen-antibody mixed solution. When the adjusting screw 14 is rotated under the driving of the second toothed disc 13, the second sliding block 23 is driven to move accurately along the track of the preparation reaction bin 1 through the threaded connection, thereby driving the sliding plate 15 to reach the specified position.

[0042] Referring to Figure 1 , Figure 3 and Figure 4 , the surface of the preparation reaction bin 1 is rotationally connected with the protective door 2 through a torsion shaft, and the middle part of the protective door 2 is provided with a transparent observation window.

[0043] The torsion shaft provides smooth rotation function, ensures smooth opening and closing action of the protective door 2 and easy control, improves the convenience of equipment use, also helps to protect the personal safety of the operator, prevents accidents during preparation, the transparent observation window provides clear vision, facilitates the operator to monitor the preparation progress and state of the antigen antibody mixed solution at any time, so as to adjust the operation parameter or take necessary measures in time.

[0044] Referring to Figure 1 、 Figure 2 、 Figure 3 And Figure 4 , four groups of supporting columns 3 are fixed at the top of the four corners of the preparation reaction bin 1, and the top of the four groups of supporting columns 3 is fixed with a top plate 4, and the middle part of the top plate 4 is installed with a driving cylinder 5;

[0045] Among them, the four groups of supporting columns 3 fixed at the top of the four corners of the preparation reaction bin 1 ensure the stability and bearing capacity of the top plate 4, so that the equipment can keep stable during operation, and the driving cylinder 5 installed in the middle part of the top plate 4 can accurately control the lifting of the moving plate 6 and the first mounting box 7 through the telescopic action.

[0046] Referring to Figure 1 、 Figure 2 、 Figure 3 And Figure 4 , the moving plate 6 is in sliding limiting connection with the four groups of supporting columns 3, and the top of the moving plate 6 is fixed with the first mounting box 7 and connected with the output end of the driving cylinder 5;

[0047] Among them, the moving plate 6 is in sliding limiting connection with the four groups of supporting columns 3, which ensures the accuracy and controllability of the moving plate 6 during movement. Through the accurate control of the driving cylinder 5, the operator can easily adjust the height of the first mounting box 7.

[0048] Referring to Figure 3 And Figure 4 , the first driving motor 8 is installed in the first mounting box 7, the output end of the first driving motor 8 is provided with stirring blades 9, and the stirring blades 9 are arranged in upper and lower correspondence with the containing container 21;

[0049] Among them, the first driving motor 8 has stable output and controllable rotating speed, which can ensure that the stirring blades 9 rotate at a constant speed, so as to realize efficient stirring of the antigen antibody mixed solution in the containing container 21.

[0050] The implementation principle of the utility model is: first, the preparation reaction bin 1 is stably placed on the appropriate position, and the protection door 2 is opened, then the control center is started first to drive the cylinder 5, the driving cylinder 5 drives the first installation box 7 and the moving plate 6 below the first installation box 7 to rise, four groups of support columns 3 provide stable limiting function to the four corners of the first installation box 7, the first driving motor 8 in the first installation box 7 drives the stirring blade 9 at the output end to rise synchronously, the second driving motor 11 is started again, the second driving motor 11 drives the first toothed disc 12 to rotate, the first toothed disc 12 is driven by the meshing with two groups of second toothed discs 13 on both sides, so that the two groups of second toothed discs 13 drive the adjusting screw rod 14 on one side to rotate, the two groups of adjusting screw rods 14 are respectively screwed with two groups of second sliding blocks 23 on the bottom of the sliding plate 15, so that the two groups of second sliding blocks 23 drive the sliding plate 15 fixed above to move in the preparation reaction bin 1, and the sliding plate 15 is clamped and slid with the preparation reaction bin 1 through the first sliding block 22 below, so that the sliding plate 15 has good support on the side close to the protection door 2 during movement, preventing abrasion with the preparation reaction bin 1 during movement;

[0051] Then, when the sliding plate 15 moves to the appropriate position, the operator rotates the adjusting bolt 19 to release the threaded fastening of the adjusting rod 18 and the fastening limiting of the slide 17, so that the adjusting rod 18 can slide in the slide 17 and the sliding plate 15, and then drive the fastening support rod 20 to move synchronously, then put the loading container 21 into the limiting ring 16, and make the fastening support rod 20 tightly fit the loading container 21 in the limiting ring 16, and then screw the adjusting bolt 19 with the adjusting rod 18, so as to fix the adjusting rod 18 to prevent it from moving with the fastening support rod 20, so that the four groups of fastening support rods 20 outside the limiting ring 16 can quickly disassemble and assemble the loading container 21 in the limiting ring 16, and can be fastened for different sizes of loading containers 21;

[0052] After that, the operator can move the sliding plate 15 into the preparation reaction bin 1 by performing the steps opposite to the above operation, and make the stirring blade 9 descend into the loading container 21, then close the protection door 2, and observe the inside of the preparation reaction bin 1 through the protection door 2, then open the first driving motor 8 through the control center, and make the first driving motor 8 drive the stirring blade 9 to mix the antigen-antibody mixture in the loading container 21 to prepare the reaction.

[0053] The parts not involved in the utility model are the same as the prior art or can be realized by using the prior art, and will not be described in detail here.

[0054] Although the embodiments of the utility model have been shown and described, the specific embodiments are only the explanation of the utility model, and are not the limitation of the utility model, the specific features, structures, materials or characteristics described can be combined in any one or more embodiments or examples in a suitable way, the person skilled in the art can make the modification, replacement and change of no creative contribution to the embodiment according to the need after reading the specification without departing from the principle and the purpose of the utility model, but as long as in the patent right claim range of the utility model, it is protected by the patent law.

Claims

1. A reaction device for preparing antigen-antibody, characterized by: Including preparation reaction bin (1), moving plate (6), second installation box (10) and sliding plate (15), the top of preparation reaction bin (1) is provided with moving plate (6), and the bottom of the back of preparation reaction bin (1) is fixed with second installation box (10), and the inside of preparation reaction bin (1) is installed with sliding plate (15); The top of sliding plate (15) is fixed with limiting ring (16), the inside of limiting ring (16) is provided with containing container (21), the outside top of limiting ring (16) is fixed with four groups of slide (17) in circumferential array, the inside of four groups of slide (17) is slidably provided with adjusting rod (18), the bottom of four groups of adjusting rod (18) is slidably connected with sliding plate (15), the top of four groups of adjusting rod (18) is threadedly connected with adjusting bolt (19), one end of four groups of adjusting rod (18) near limiting ring (16) is fixed with fastening support rod (20), fastening support rod (20) is slidably connected with limiting ring (16), and fastening support rod (20) is abuttingly connected with containing container (21).

2. The reaction device for preparing antigen-antibody according to claim 1, characterized in that: The back of second installation box (10) is provided with second drive motor (11), the output end of second drive motor (11) is provided with first toothed disc (12), and first toothed disc (12) is rotatably connected with preparation reaction bin (1).

3. The reaction device for preparing antigen-antibody according to claim 2, characterized in that: The two sides of first toothed disc (12) are rotatably connected with two groups of second toothed disc (13), and the two groups of second toothed disc (13) are rotatably connected with second installation box (10), and the side of two groups of second toothed disc (13) near preparation reaction bin (1) is rotatably connected with adjusting screw rod (14).

4. The reaction device for preparing antigen-antibody according to claim 1, characterized by: The bottom of sliding plate (15) is fixed with first sliding block (22), and slidably connected with preparation reaction bin (1), the bottom of sliding plate (15) and the two sides of first sliding block (22) are fixed with two groups of second sliding block (23), and are respectively threadedly connected with two groups of adjusting screw rod (14), and the two groups of second sliding block (23) are slidably connected with preparation reaction bin (1).

5. The reaction device for preparing antigen-antibody according to claim 1, characterized by: The surface of preparation reaction bin (1) is rotatably connected with protection door (2) through torsion shaft, and the middle of protection door (2) is provided with transparent observation window.

6. The reaction device for preparing antigen-antibody according to claim 1, characterized by: The top of preparation reaction bin (1) is rotatably connected with protection door (2) through torsion shaft, and the middle of protection door (2) is provided with transparent observation window.

7. The reaction device for preparing antigen-antibody according to claim 1, characterized by: The top of preparation reaction bin (1) is rotatably connected with protection door (2) through torsion shaft, and the middle of protection door (2) is provided with transparent observation window.

8. The reaction device for preparing antigen-antibody according to claim 7, characterized by: The top of preparation reaction bin (1) is rotatably connected with protection door (2) through torsion shaft, and the middle of protection door (2) is provided with transparent observation window. The top of preparation reaction bin (1) is rotatably connected with protection door (2) through torsion shaft, and the middle of protection door (2) is provided with transparent observation window.

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