Multifunctional die body integrating CT (Computed Tomography) and fluorescence imaging detection

Abstract

The utility model provides a multifunctional die body integrating CT (Computed Tomography) and fluorescence imaging detection, and mainly relates to the technical field of CT and fluorescence measurement. A multifunctional die body integrating CT and fluorescence imaging detection comprises a cylindrical body die body and a head die body embedded in the body die body, the head die body is connected with a supporting body, the interior of the supporting body is hollow, countersunk through holes are formed in the centers and the peripheries of the body die body and the head die body, a cylinder is inserted into each through hole, and the head die body is connected with the supporting body. A fluorescent substance accommodating part is arranged in the cylinder, the cylinder is inserted into the through hole when the fluorescent dose is measured, and a detector is inserted into the through hole to be connected with an ionization chamber dosimeter for displaying the CT dose when the CT dose is measured.

Description

TECHNICAL FIELD

[0001] The utility model mainly relates to CT and fluorescence measurement technical field, concretely is a kind of integrated CT and the multifunctional phantom of fluorescence imaging detection. BACKGROUND

[0002] With the development of medical imaging technology, computer tomography and fluorescence imaging have become indispensable tools in clinical diagnosis. Computer tomography is widely used in the diagnosis and monitoring of various diseases due to its high resolution and fast imaging capability. Fluorescence imaging is widely used in biomedical research and clinical applications due to its high sensitivity and specificity to biological samples.

[0003] However, while these imaging techniques provide high-definition images, they also come with certain radiation dose or fluorescent agent usage problems. The accumulation of radiation dose poses potential health risks to patients, while the use of fluorescent agents may cause allergic reactions or other side effects. Therefore, accurate measurement and control of dose during imaging are crucial for patient safety and improving imaging quality.

[0004] Currently, there are various dose detection phantoms on the market for assessing dose distribution during CT scanning and fluorescence imaging. Existing phantoms are often designed for only one type of imaging technology, lacking the versatility to adapt to different imaging modes. To address the above problems, the present invention provides a new type of multifunctional phantom for integrated CT and fluorescence imaging detection, aiming to overcome the shortcomings of existing technology through innovative material selection, structural design and functional integration, and achieve more stable and reliable and multifunctional dose detection. UTILITY MODEL CONTENT

[0005] The purpose of the present invention is to provide a CT and fluorescence imaging dose detection multifunctional phantom with stable performance, which can measure CT and fluorescence imaging dose separately.

[0006] To achieve the above purpose, the present invention adopts the following technical solutions:

[0007] A multifunctional phantom for integrated CT and fluorescence imaging detection includes a cylindrical body phantom and a head phantom embedded in the body phantom. The head phantom is connected to a support body, which is hollow inside. The body phantom and the head phantom have sink holes in the center and around the circumference. Each hole has a circular cylinder inserted into it. The circular cylinder contains a fluorescent substance container. To measure the fluorescence dose, insert the circular cylinder into the hole. To measure the CT dose, insert the probe into the hole and connect it to the ionization chamber dosimeter to display the CT dose.

[0008] By adopting the technical scheme, when the phantom is detected, the head phantom is put into the body phantom to form a complete phantom, a circular column is inserted into each through hole of the head phantom, the phantom is placed on a detection table, the phantom is vertically placed on the detection table when the CT dose is detected, the probe is inserted into one of the countersunk through holes of the body phantom, and the remaining countersunk through holes are closed by inserting the circular columns. After one through hole is detected, the probe is inserted into the next through hole, the circular column is inserted into the detected through hole, and the above steps are repeated until each through hole is detected. The support connected to the phantom prevents the phantom from shaking during detection to a certain extent. When the fluorescent dose is detected, the phantom is horizontally placed beside the detected part of the object, the circular column is inserted into the countersunk through hole, the fluorescent substance containing part in the circular column contains fluorescent pigments of a specified concentration, near-infrared light is irradiated on the object and the phantom of the application, the brightness of the fluorescent light from the object and the phantom is compared and observed, and thus the concentration of the fluorescent pigments in the object is compared with the brightness of the fluorescent pigments in the fluorescent body phantom to quantitatively measure.

[0009] Further, the support is connected to the head phantom.

[0010] Further, the support is a hollow cuboid, and the length and width of the support are equal to the diameter of the body phantom.

[0011] Further, the body phantom is uniformly provided with countersunk through holes around the body phantom, and the inner diameter of the body phantom is equal to the outer diameter of the head phantom.

[0012] Further, the head phantom is provided with countersunk through holes at the center and around the head phantom, and the head phantom is connected to the support.

[0013] Further, the countersunk through hole is inserted with the detection sensor connected to the ionization chamber dosimeter.

[0014] Further, the countersunk through hole is inserted with the circular column, and the circular column contains a fluorescent substance containing part.

[0015] Further, the top of the circular column is connected to a circular truncated cone.

[0016] Further, the fluorescent substance containing part contains concentrated fluorescent pigments, and the same concentration of fluorescent pigments is arranged at different depths in each circular column.

[0017] Further, the fluorescent substance is indocyanine green, which has good tissue penetration, and its near-infrared light absorption and emission characteristics enable it to produce clear fluorescent signals in deep tissues, is suitable for imaging of deep parts in the body, has relatively fast metabolism and excretion in the body, has less adverse effects on the human body, can be quickly removed from the blood circulation, reduces background interference, improves the accuracy and specificity of imaging, selectively accumulates in certain specific tissues or lesion sites, helps precise imaging and diagnosis of these sites, perfectly matches advanced near-infrared fluorescence imaging equipment, can provide high-quality images, and can realize real-time and dynamic imaging, helping doctors to observe and evaluate the blood perfusion and functional state of tissues in real time during surgery, and indocyanine green belongs to organic dyes, which has no obvious attenuation to X-rays and has little effect on the measurement of X-ray dose.

[0018] Further, the materials used for the phantom are all epoxy resins with a certain proportion of titanium dioxide. Titanium dioxide can effectively simulate the scattering of X-ray and fluorescence by tissues, while the cured epoxy resin has the disadvantages of brittleness and poor impact resistance, limiting its application. However, nano-titanium dioxide can continuously and effectively degrade toxic and harmful gases such as formaldehyde and toluene due to its special photocatalytic and catalytic functions. Adding it to the epoxy resin can improve the hardness, impact strength, and wear resistance of the original coating, effectively shield the damage of ultraviolet rays to the body membrane, and improve the weather resistance of the phantom. The phantom made of titanium dioxide and epoxy resin composite material can also improve the clarity and accuracy of imaging.

[0019] Compared with the prior art, the present application has the following advantages:

[0020] The present application can be used to detect the concentration of CT dose and fluorescent pigment. By providing a support device connected to the head phantom, the movement of the phantom during detection can be prevented to some extent, and the stability of the device can be improved. BRIEF DESCRIPTION OF DRAWINGS

[0021] Figure 1 is a structural schematic diagram of the present application;

[0022] Figure 2 is a perspective view of the structure of the present application;

[0023] Figure 3 is a top view of the present application;

[0024] Figure 4 is a circular column of the present application.

[0025] Reference signs shown in the drawings: 1, head phantom; 2, body phantom; 3, support; 4, circular column; 5, fluorescent substance containing part; 6, countersunk hole; 7, circular truncated cone. DETAILED DESCRIPTION

[0026] The utility model will be further described in connection with the drawings and specific embodiments. It should be understood that these embodiments are only used for illustrating the utility model and are not used for limiting the scope of the utility model. In addition, it should be understood that after reading the content taught by the utility model, those skilled in the art can make various changes or modifications to the utility model, and these equivalent forms also fall within the scope defined by the present application.

[0027] Embodiment: a multifunctional phantom of integrated CT and fluorescence imaging detection

[0028] As shown in Figure 1 , 2 , a CT and fluorescence dose detection phantom, comprising a cylindrical body phantom 2 and a head phantom 1 inlaid in the body phantom 2, the head phantom 1 is connected with a support body 3, the inside of the support body 3 is hollow, the center and the periphery of the body phantom 2 and the head phantom 1 are provided with countersunk through holes 6, a circular cylinder 4 is inserted in each through hole, the circular cylinder 4 contains a fluorescence substance containing part 5, and the top of the circular cylinder 4 is connected with a circular truncated cone 7. When measuring the fluorescence dose, the circular cylinder 4 is inserted into the through hole 6, when measuring the CT dose, a detector is inserted into the through hole 6 and connected with an ionization chamber dosimeter for displaying the CT dose. X-rays are emitted from a CT scanner, irradiate the detector in the circular through hole 6 in the phantom after passing through the phantom, X-ray photons interact with the material in the detector, secondary electrons are generated, these electrons collide with atoms in the material, causing ionization. In the ionization chamber, the positive and negative ions generated by ionization are separated under the action of an electric field, the separation and movement of electric charges form an electric current between the two electrodes of the ionization chamber, when the current signal is transmitted from the ionization chamber, it first enters a preamplifier and a main amplifier for amplification, the amplified signal passes through a signal conditioning circuit, removes noise and performs integration and other processing to obtain an analog electric signal related to the X-ray dose, an analog-to-digital converter converts this analog signal into a digital signal, which is sent to a microprocessor, the microprocessor calculates the digital signal according to the pre-stored calibration parameters and measurement algorithm, establishes a quantitative relationship between the current and the dose according to parameters such as the sensitive volume of the ionization chamber, the ionization energy of the gas, and the effective area of the collection electrode, the microprocessor uses these relationships and the results of signal processing to calculate the final CT dose value, which can then be stored in a storage unit and sent to external equipment through a communication interface to display the CT dose.

[0029] As shown in Figure 2 , 3As shown, when the phantom is detected, the head phantom 1 is put into the body phantom 2 to form a complete phantom, the circular column 4 is inserted into each through hole of the head phantom, the phantom is placed on the detection table, the phantom is vertically placed on the detection table when the CT dose is detected, the probe is inserted into one of the countersunk through holes 6 of the body phantom, and the remaining countersunk through holes 6 are closed by inserting the circular column 4. After one through hole 6 is detected, the probe is inserted into the next through hole 6, the circular column 4 is inserted into the detected through hole 6, and the above steps are repeated until each through hole 6 is detected. Through the support connected to the phantom, the shaking of the phantom during detection is prevented to a certain extent. When the fluorescent dose is detected, the phantom is horizontally placed beside the detected part of the object, the circular column 4 is inserted into the countersunk through hole 6, the fluorescent material containing part 5 in the circular column 4 contains a specified concentration of fluorescent pigment, the object and the phantom of the application are irradiated with near-infrared light, the fluorescent brightness of the fluorescent material in the phantom is compared with the fluorescent brightness of the fluorescent material in the phantom, and the concentration of the fluorescent pigment in the object is quantitatively measured.

[0030] In the interpretation of the utility model, it should be pointed out that the terms representing the direction are only used for convenient description and understanding, and are not the only limitation of the installation position of the specific technical features, and other installation methods that can be realized are not excluded.

[0031] Finally, it should be pointed out that: the above examples are only used to illustrate the technical scheme of the utility model, and are not limited to it; although the utility model has been described in detail with reference to the foregoing examples, those skilled in the art should understand that: it can still modify the technical scheme recorded in the foregoing examples, or make equivalent replacement for part of the technical features; and these modifications or replacements do not make the essence of the corresponding technical scheme deviate from the spirit and scope of the technical scheme of the utility model.

Claims

1. A multi-functional phantom for integrated CT and fluorescence imaging detection, comprising a body phantom, characterized in that: The body model is inlaid with a head model inside, the head model is connected with the support body, the center of the head model, the periphery of the head model and the periphery of the body model are uniformly provided with circular through holes, each of the through holes is inserted with a circular column, the circular column contains a fluorescent substance containing part, the model is connected with an ionization chamber dosimeter, and a detection sensor is inserted into the circular through hole.

2. The multi-functional phantom of integrated CT and fluorescence imaging detection according to claim 1, characterized in that, The support body is connected with the head model.

3. The multi-functional phantom of integrated CT and fluorescence imaging detection according to claim 1, characterized in that, The support body is a hollow cuboid, and the length and width of the support body are equal to the diameter of the body model.

4. The multi-functional phantom of claim 1, wherein, The body model is uniformly provided with through holes around, and the inner diameter of the body model is equal to the outer diameter of the head model.

5. The multi-functional phantom of integrated CT and fluorescence imaging detection according to claim 1, characterized in that, The head model is connected with the support body.

6. The multi-functional phantom of integrated CT and fluorescence imaging detection according to claim 1, characterized in that, The detection sensor is connected with the ionization chamber dosimeter.

7. The multi-functional phantom of integrated CT and fluorescence imaging detection according to claim 4 or 5, characterized in that, The circular column is inserted into the through hole, and the circular column contains a fluorescent substance containing part.

8. The multi-functional phantom of integrated CT and fluorescence imaging detection according to claim 7, characterized in that, The top of the circular column is connected with a circular truncated cone.

9. The multi-functional phantom of integrated CT and fluorescence imaging detection according to claim 1, characterized in that, The fluorescent substance containing part contains concentrated fluorescent pigments, and the same concentration of fluorescent pigments is arranged at different depths in each circular column.

10. The multi-functional phantom of integrated CT and fluorescence imaging detection according to claim 8, characterized in that, The fluorescent substance is indocyanine green.

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