Pipetting device and dyeing instrument

Abstract

The utility model discloses a pipetting device and dyeing instrument, including X-axis motion subassembly, Y-axis motion subassembly and Z-axis motion subassembly, X-axis motion subassembly includes X-axis base plate and two sets of X-axis transmission subassembly symmetrically arranged on the X-axis base plate, the number of Y-axis motion subassembly and Z-axis motion subassembly is equal to the number of X-axis transmission subassembly, the X-axis transmission subassembly is connected with the X-axis base plate. The X-axis transmission assembly, the Y-axis transmission assembly and the Z-axis transmission assembly are synchronous belt transmission assemblies. The double-arm pipetting mechanism comprises an X-axis movement assembly, Y-axis movement assemblies and Z-axis movement assemblies, the X-axis movement assembly comprises two sets of X-axis transmission assemblies symmetrically arranged on an X-axis bottom plate, the number of the Y-axis movement assemblies and the number of the Z-axis movement assemblies are equal to the number of the X-axis transmission assemblies, and through the double-arm pipetting mechanism, the working efficiency is high, the parallel operation capacity is high, and the working efficiency is high. According to the double-arm pipetting mechanism, the overall balance and stability can be kept through coordination of double arms in the pipetting process, and the pipetting mechanism is small in size and high in space utilization rate.

Description

Technical Field

[0001] This utility model relates to the field of detection technology, and in particular to a pipetting device and a staining instrument. Background Technology

[0002] In automated medical testing equipment, specialized pipetting mechanisms are often required. A pipetting mechanism is a device or apparatus used for the precise transfer of liquids, widely used in fields such as biology, chemistry, and medicine. Currently, most common staining instruments use single-arm pipetting mechanisms, which no longer possess the hardware characteristics for high-efficiency operation. Furthermore, these mechanisms are bulky, have low space utilization, and do not meet the requirements for lightweight design. Summary of the Invention

[0003] In order to overcome the shortcomings of the existing technology, the purpose of this utility model is to realize a lightweight double-arm pipetting device and staining instrument with multi-dimensional motion.

[0004] The objective of this utility model is achieved through the following technical solution:

[0005] A pipetting device includes a frame and a three-dimensional motion assembly located on the frame. The three-dimensional motion assembly includes an X-axis motion assembly, a Y-axis motion assembly, and a Z-axis motion assembly. The X-axis motion assembly includes an X-axis output slider, an X-axis base plate, and two sets of X-axis transmission assemblies symmetrically arranged on the X-axis base plate. The number of Y-axis and Z-axis motion assemblies is equal to the number of X-axis transmission assemblies. The Y-axis motion assembly includes a Y-axis base plate and a Y-axis transmission assembly. The Y-axis base plate is located above the X-axis output slider and is fixedly connected to it. The Z-axis motion assembly includes a Z-axis brake motor mounting base and a Z-axis transmission assembly. The Z-axis brake motor mounting base is located above the Y-axis base plate and is fixedly connected to it. The X-axis, Y-axis, and Z-axis transmission assemblies are synchronous belt drive assemblies. The pipetting device also includes a suction assembly fixed below the Z-axis motion assembly.

[0006] Preferably, the X-axis transmission assembly includes an X-axis motor, a driving wheel, a driven wheel, a timing belt, a timing belt pressure plate, and a slider adapter plate. The output shaft of the X-axis motor is connected to the driving wheel, the driving wheel and the driven wheel are connected through the timing belt, the timing belt is fixed to the slider adapter plate through the timing belt pressure plate, and the X-axis output slider is fixedly connected to the slider adapter plate.

[0007] Preferably, the pipetting device further includes a magnetic scale and a magnetic scale reading head, and the X-axis motion assembly further includes a side plate, with the magnetic scale fixed on the side plate and the magnetic scale reading head fixed on the X-axis output slider.

[0008] Preferably, the X-axis motion assembly further includes an X-axis guide rail, which is located on the X-axis base plate, and the X-axis output slider is slidably connected to the X-axis guide rail.

[0009] Preferably, the two sets of X-axis transmission components are symmetrically arranged and slidably connected to the X-axis guide rail via the X-axis output slider.

[0010] Preferably, the pipetting device further includes an optical coupler and a baffle plate, the optical coupler being located on one side of the X-axis guide rail and fixed on the X-axis base plate, and the baffle plate being located on the X-axis output slider.

[0011] Preferably, the Y-axis transmission assembly includes a Y-axis motor, a Y-axis motor mounting base, and a gear retainer. The Y-axis motor is fixed to the Y-axis base plate by the Y-axis motor mounting base, and the synchronous belt is fixed to the gear retainer by the synchronous belt pressure plate, so that the rotational motion of the Y-axis motor is converted into the linear motion of the gear retainer in the Y direction.

[0012] Preferably, the Z-axis transmission assembly includes a Z-axis brake motor, a Z-axis bearing housing, a splined drive shaft, a splined rack, and a splined gear. The Z-axis brake motor is fixed to the Y-axis base plate via the Z-axis brake motor mounting bracket. The splined drive shaft is connected to the output end of the Z-axis brake motor. The Z-axis bearing housing supports the splined drive shaft and allows it to pass through the gear retainer. The splined rack and the splined gear mesh, so that the rotational motion of the Z-axis brake motor is converted into the linear motion of the splined rack in the Z direction.

[0013] Preferably, the pipetting device further includes a grating disk and a grating reading head. The grating disk is fixedly connected to the output shaft of the Z-axis brake motor, and the grating reading head is fixed below the grating disk. The grating disk is partially located inside the grating reading head, and the rotation of the grating disk cuts the transmitted light rays of the grating reading head.

[0014] A staining instrument, including the aforementioned pipetting device.

[0015] Compared with existing technologies, the pipetting device of this invention has the following advantages:

[0016] The pipetting device of this application is a three-dimensional motion assembly, including an X-axis motion assembly, a Y-axis motion assembly, and a Z-axis motion assembly. The X-axis motion assembly includes two sets of X-axis transmission assemblies symmetrically arranged on the X-axis base plate. The number of Y-axis motion assemblies and Z-axis motion assemblies is equal to the number of X-axis transmission assemblies. Through the dual-arm pipetting mechanism, the working efficiency is high and the parallel operation capability is strong. During the pipetting process, the dual-arm pipetting mechanism can maintain the overall balance and stability through the coordinated cooperation of the two arms. Moreover, the pipetting mechanism is small in size, has a high space utilization rate, and meets the characteristics of lightweight design. Attached Figure Description

[0017] Figure 1 This is a schematic diagram of the pipetting device of this application;

[0018] Figure 2 for Figure 1 A schematic diagram of the X-axis motion component;

[0019] Figure 3 for Figure 2 Exploded view of the X-axis motion component;

[0020] Figure 4 for Figure 1 A schematic diagram of the Y-axis motion component;

[0021] Figure 5 This is a schematic diagram of the Y-axis motion assembly and the barcode scanning assembly of the pipetting device of this application;

[0022] Figure 6 This is a schematic diagram of the Z-axis motion component and the aspiration component of the pipetting device of this application.

[0023] In the diagram: 100, frame; 200, X-axis motion assembly; 201, X-axis base plate; 202, X-axis motor; 203, driving wheel; 204, driven wheel; 205, synchronous belt; 206, synchronous belt pressure plate; 207, slider adapter plate; 208, X-axis output slider; 209, side plate; 210, X-axis guide rail; 300, Y-axis motion assembly; 301, Y-axis base plate; 302, Y-axis motor; 303, Y-axis motor mounting base; 304, gear cage; 400, Z-axis motion assembly; 4 01. Z-axis brake motor mounting base; 402. Z-axis brake motor; 403. Z-axis bearing housing; 404. Splined drive shaft; 405. Splined gear; 406. Grating disk; 407. Grating reader; 408. Z-axis synchronous pulley; 409. Splined rack; 500. Barcode scanning assembly; 501. Barcode scanning lens; 600. Suction assembly; 601. Liquid level detection component; 602. Mounting plate; 603. Sampling needle; 700. Optical coupler; 800. Baffle; 900. Magnetic scale; 1000. Magnetic scale reader. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] It should be noted that when a component is said to be "fixed to" another component, it can be directly on the other component or it can be fixed through another intermediate component. When a component is said to be "connected to" another component, it can be directly connected to the other component or it may be fixed through another intermediate component. When a component is said to be "set on" another component, it can be set directly on the other component or it may be set through another intermediate component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.

[0026] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0027] Figures 1-6 This utility model discloses a pipetting device, including a frame 100 and a three-dimensional motion assembly located on the frame 100. The three-dimensional motion assembly includes an X-axis motion assembly 200, a Y-axis motion assembly 300, and a Z-axis motion assembly 400. The X-axis motion assembly 200 includes an X-axis output slider 208. The Y-axis motion assembly 300 includes a Y-axis base plate 301 and a Y-axis transmission assembly. The Y-axis base plate 301 is located above and fixedly connected to the X-axis output slider 208. The Z-axis motion assembly 400 includes a Z-axis brake motor mounting base 401 and a Z-axis transmission assembly. The Z-axis brake motor mounting base 401 is located above and fixedly connected to the Y-axis base plate 301.

[0028] like Figure 2 , Figure 3As shown, the X-axis motion assembly 200 includes an X-axis base plate 201 and two sets of X-axis transmission assemblies symmetrically arranged on the X-axis base plate 201. The X-axis transmission assemblies include an X-axis motor 202, a driving wheel 203, a driven wheel 204, a synchronous belt 205, a synchronous belt pressure plate 206, and a slider adapter plate 207. The output shaft of the X-axis motor 202 is connected to the driving wheel 203. The driving wheel 203 and the driven wheel 204 are connected by the synchronous belt 205. The synchronous belt 205 is fixed on the slider adapter plate 207 by the synchronous belt pressure plate 206. The X-axis output slider 208 is fixedly connected to the slider adapter plate 207.

[0029] Specifically, the number of Y-axis motion components 300 and Z-axis motion components 400 is equal to the number of X-axis transmission components.

[0030] Specifically, the X-axis drive assembly, Y-axis drive assembly, and Z-axis drive assembly are synchronous belt drive assemblies.

[0031] The X-axis motion assembly 200 also includes an X-axis guide rail 210, which is fixed on the X-axis base plate 201. The X-axis output slider 208 is slidably connected to the X-axis guide rail 210.

[0032] Specifically, the two sets of X-axis transmission components are arranged symmetrically and are slidably connected to the X-axis guide rail 210 through the X-axis output slider 208.

[0033] like Figure 4 , Figure 5 As shown, the Y-axis transmission assembly includes a Y-axis motor 302, a Y-axis motor mounting base 303, and a gear cage 304. The Y-axis motor 302 is fixed to the Y-axis base plate 301 by the Y-axis motor mounting base 303, and the synchronous belt 205 is fixed to the gear cage 304 by the synchronous belt pressure plate 206, so that the rotational motion of the Y-axis motor 302 is converted into the linear motion of the gear cage 304 in the Y direction.

[0034] like Figure 6 As shown, the Z-axis transmission assembly 400 includes a Z-axis brake motor 402, a Z-axis bearing housing 403, a splined drive shaft 404, and a splined gear 405. The Z-axis brake motor 402 is fixed on the Y-axis base plate 301 via a Z-axis brake motor mounting base 401. The splined drive shaft 404 is connected to the output end of the Z-axis brake motor 402. The Z-axis synchronous pulley 408 is mechanically connected to the splined drive shaft 404. The Z-axis bearing housing 403 supports both ends of the splined gear 405 within the gear cage 304. The splined rack 409 meshes with the splined gear 405, causing the rotational motion of the Z-axis brake motor 402 to become the linear motion of the splined rack 409 in the Z direction.

[0035] The Z-axis motion assembly also includes a grating disk 406 and a grating reader 407. The grating disk 406 is fixedly connected to the output shaft of the Z-axis brake motor 402, and the grating reader 407 is fixed below the grating disk 406. The grating disk 406 is partially located inside the grating reader 407, and the rotation of the grating disk 406 cuts the beam of light emitted from the grating reader 407.

[0036] The pipetting device also includes a barcode scanning component 500 and an aspiration component 600, with the barcode scanning component 500 located to one side of the aspiration component 600. The barcode scanning component 500 includes a barcode scanning lens 501 and a barcode scanning main control. The barcode scanning main control is electrically connected to the barcode scanning lens 501, and the barcode scanning lens 501 scans the QR code on the reagent kit to retrieve reagent information.

[0037] Specifically, the number of scanning lenses 501 can be selected as a single lens or multiple lenses depending on the number of reagent kits.

[0038] The aspiration assembly 600 includes a sampling needle 603, which and a spline rack 409 are fixed to a mounting plate 602. The sampling needle 603 and the spline rack 409 move in the same linear direction in the Z direction.

[0039] The liquid level detector 601 determines the height of the liquid level in the reagent kit by detecting the capacitance of the sample dispensing needle 603, thereby realizing the dynamic monitoring function of the remaining reagent volume.

[0040] The pipetting device also includes an optocoupler 700 and a baffle 800. In the X-direction, the optocoupler 700 is located outside the X-axis guide rail 210 and fixed to the X-axis base plate 201, while the baffle 800 is located on the X-axis output slider 208. In the X-direction, the optocoupler 700 is the zero point of the left X-axis; after the device is powered on, the left X-axis is reset by moving the left X-axis baffle 800. In the Y-direction, the optocoupler 700 is the zero point of the gear cage 304; after the device is powered on, the gear cage 304 is reset by moving the baffle 800. In the Z-direction, the optocoupler 700 is the zero point of the Z-axis; after the device is powered on, the Z-axis is reset by moving the baffle 800.

[0041] The pipetting device also includes a magnetic scale 900 and a magnetic scale reader 1000. In the X-direction, the X-axis motion assembly 200 further includes a side plate 209. The magnetic scale 900 is fixed to the side plate 209, and the magnetic scale reader 1000 is fixed to the X-axis output slider 208. The magnetic scale reader 1000 forms a closed loop in the X-axis by recognizing the magnetic force of the magnetic scale 900. In the Y-direction, the magnetic scale reader 1000 is mounted on one side of the synchronous belt pressure plate 206 and forms a closed loop in the Y-axis by recognizing the magnetic force of the magnetic scale 900.

[0042] A staining instrument, including a pipetting device.

[0043] In this application, the pipetting device is initially positioned with the X, Y, and Z axes all at their respective zero points. The reagent kit is placed in its fixed position, which can be any position within the working area of ​​the pipetting arm. The program starts and scans the reagent kit information. After the host computer sends a command, the X-axis motion component 200 and the Y-axis motion component 300 move simultaneously. The output shaft of the X-axis motor 202 is connected to the drive wheel 203, which is connected to the driven wheel 204 via a synchronous belt 205. The synchronous belt 205 is fixed to the slider adapter plate 207 via a synchronous belt pressure plate 206. The X-axis output slider 208 is fixedly connected to the slider adapter plate 207, causing the X-axis output slider 208 to slide against the X-axis guide rail 210, further driving the Y-axis motion component 300 to move in the X direction. This positions the scanning lens 501 directly above the reagent kit's QR code, and then scans the QR code information. Technicians can select between single-lens or dual-lens scanning on the host computer depending on the number of reagent kits. After reagent preparation and scanning, the X-axis motion component 200 and Y-axis motion component 300 move again to position the sample dispensing needle 603 directly above the reagent kit. Similarly, technicians can select single-needle or double-needle aspiration on the host computer according to the required number of reagent aspirations. For reagent aspiration, the Z-axis moves downwards until it enters the reagent liquid surface, then aspiration begins. After aspiration, the Z-axis moves upwards, and the dispensing needle 603 leaves the reagent liquid surface. The Y-axis dispensing needle plunger pump continues to maintain a negative pressure state. During reagent aspiration, the liquid level detection element 601 determines the height of the liquid level in the reagent kit by detecting the capacitance of the dispensing needle 603, thereby achieving dynamic monitoring of the remaining reagent level. For reagent release, the X-axis motion component 200, Y-axis motion component 300, and Z-axis motion component 400 move simultaneously, causing the dispensing needle 603 to reach the preset designated position for reagent release. Then, the Y-axis dispensing needle plunger pump activates a positive pressure state to release the reagent. The dispensing needle 603 undergoes internal and external washing. After each reagent aspiration, the 603 sample needle needs to be washed internally and externally, which is performed by other modules. After the pipetting is completed, the X-axis motion assembly 200, Y-axis motion assembly 300, and Z-axis motion assembly 400 are zero-point reset through the cooperation of the optocoupler 700 and the baffle 800.

[0044] The pipetting device of this application is a three-dimensional motion assembly, including an X-axis motion assembly 200, a Y-axis motion assembly 300, and a Z-axis motion assembly 400. The X-axis motion assembly 200 includes two sets of X-axis transmission assemblies symmetrically arranged on the X-axis base plate 201. The number of Y-axis motion assemblies 300 and Z-axis motion assemblies 400 is equal to the number of X-axis transmission assemblies. Through the dual-arm pipetting mechanism, the working efficiency is high and the parallel operation capability is strong. During the pipetting process, the dual-arm pipetting mechanism can maintain the overall balance and stability through the coordinated cooperation of the two arms. Moreover, the pipetting mechanism is small in size, has high space utilization, and meets the characteristics of lightweight design.

[0045] The above embodiments only illustrate several implementation methods of this utility model, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the utility model patent. It should be noted that for those skilled in the art, several modifications and improvements can be made without departing from the concept of this utility model. These are all equivalent modifications and improvements made to the above embodiments based on the essential technology of this utility model, and all of these fall within the protection scope of this utility model.

Claims

1. A pipetting device, comprising a frame, characterized in that: The pipetting device further includes a three-dimensional motion assembly located on the frame. The three-dimensional motion assembly includes an X-axis motion assembly, a Y-axis motion assembly, and a Z-axis motion assembly. The X-axis motion assembly includes an X-axis output slider, an X-axis base plate, and two sets of X-axis transmission assemblies symmetrically arranged on the X-axis base plate. The number of Y-axis motion assemblies and Z-axis motion assemblies is equal to the number of X-axis transmission assemblies. The Y-axis motion assembly includes a Y-axis base plate and a Y-axis transmission assembly. The Y-axis base plate is located above the X-axis output slider and is fixedly connected to it. The Z-axis motion assembly includes a Z-axis brake motor mounting base and a Z-axis transmission assembly. The Z-axis brake motor mounting base is located above the Y-axis base plate and is fixedly connected to it. The X-axis transmission assembly, Y-axis transmission assembly, and Z-axis transmission assembly are synchronous belt drive assemblies. The pipetting device also includes a suction assembly fixed below the Z-axis motion assembly.

2. The pipetting device according to claim 1, characterized in that: The X-axis transmission assembly includes an X-axis motor, a driving wheel, a driven wheel, a timing belt, a timing belt pressure plate, and a slider adapter plate. The output shaft of the X-axis motor is connected to the driving wheel. The driving wheel and the driven wheel are connected through the timing belt. The timing belt is fixed to the slider adapter plate through the timing belt pressure plate. The X-axis output slider is fixedly connected to the slider adapter plate.

3. The pipetting apparatus according to claim 1, characterized in that: The pipetting device also includes a magnetic scale and a magnetic scale reading head. The X-axis motion assembly also includes a side plate. The magnetic scale is fixed on the side plate, and the magnetic scale reading head is fixed on the X-axis output slider.

4. The pipetting apparatus according to claim 1, characterized in that: The X-axis motion assembly also includes an X-axis guide rail, which is located on the X-axis base plate, and the X-axis output slider is slidably connected to the X-axis guide rail.

5. The pipetting apparatus according to claim 4, characterized in that: The two sets of X-axis transmission components are symmetrically arranged and are slidably connected to the X-axis guide rail through the X-axis output slider.

6. The pipetting apparatus according to claim 4, characterized in that: The pipetting device also includes an optical coupler and a baffle. The optical coupler is located on one side of the X-axis guide rail and fixed on the X-axis base plate, and the baffle is located on the X-axis output slider.

7. The pipetting apparatus according to claim 2, characterized in that: The Y-axis transmission assembly includes a Y-axis motor, a Y-axis motor mounting base, and a gear cage. The Y-axis motor is fixed to the Y-axis base plate by the Y-axis motor mounting base, and the synchronous belt is fixed to the gear cage by the synchronous belt pressure plate, so that the rotational motion of the Y-axis motor is converted into the linear motion of the gear cage in the Y direction.

8. The pipetting apparatus according to claim 7, characterized in that: The Z-axis transmission assembly includes a Z-axis brake motor, a Z-axis bearing housing, a splined drive shaft, a splined rack, and a splined gear. The Z-axis brake motor is fixed to the Y-axis base plate via a Z-axis brake motor mounting bracket. The splined drive shaft is connected to the output end of the Z-axis brake motor. The Z-axis bearing housing supports the splined drive shaft and allows it to pass through the gear retainer. The splined rack and the splined gear mesh, causing the rotational motion of the Z-axis brake motor to become the linear motion of the splined rack in the Z direction.

9. The pipetting apparatus according to claim 8, characterized in that: The pipetting device also includes a grating disk and a grating reading head. The grating disk is fixedly connected to the output shaft of the Z-axis brake motor, and the grating reading head is fixed below the grating disk. The grating disk is partially located inside the grating reading head, and the rotation of the grating disk cuts the through-beams of the grating reading head.

10. A staining instrument, characterized in that: Includes the pipetting apparatus as described in any one of claims 1 to 9.

Images