Slide rack

Abstract

The utility model discloses a slide rack, which belongs to the field of immunohistochemical staining and comprises a base, a driving component, a mounting seat, a heating film, a vibrating motor, a connecting component and a heating table, the mounting seat is rotatably mounted on the base, the driving component is mounted on the base and is in transmission connection with the mounting seat, and the driving component drives the mounting seat to rotate relative to the base. The heating table is mounted on the mounting seat through the connecting assembly, the heating film and the vibration motor are mounted between the heating table and the mounting seat, the heating table is provided with a mounting groove, the mounting groove is used for mounting a slide, the heating film heats the slide, the vibration motor drives the heating table to vibrate, and antibody molecule movement is accelerated through vibration generated by the vibration motor; the antigen-antibody collision binding efficiency is improved, the antigen-antibody reaction is accelerated, and the antigen-antibody reaction time is shortened.

Description

Technical Field

[0001] This utility model relates to the field of immunohistochemical staining, and in particular to slide holders. Background Technology

[0002] In the field of immunohistochemical staining technology, existing immunohistochemical staining equipment has a long detection time and cannot perform rapid immunohistochemical staining on frozen sections, thus failing to support pathologists in making accurate diagnoses of frozen sections in a short period of time. Utility Model Content

[0003] In order to overcome the shortcomings of the prior art, one of the objectives of this utility model is to provide a slide holder that can shorten the detection time.

[0004] One of the objectives of this utility model is achieved through the following technical solution:

[0005] A slide holder includes a base, a drive assembly, a mounting base, a heating film, a vibration motor, a connecting assembly, and a heating stage. The mounting base is rotatably mounted on the base. The drive assembly is mounted on the base and is drively connected to the mounting base, driving the mounting base to rotate relative to the base. The heating stage is mounted on the mounting base via the connecting assembly. The heating film and the vibration motor are mounted between the heating stage and the mounting base. The heating stage has a mounting groove for mounting slides. The heating film heats the slides, and the vibration motor drives the heating stage to vibrate.

[0006] Furthermore, there is a gap between the mounting base and the heating platform.

[0007] Furthermore, the connecting assembly includes a first elastic element and a connecting element. The first elastic element is mounted on the mounting base, and both ends of the first elastic element are respectively fixedly connected to the two connecting elements. The connecting elements are fixed to the heating table.

[0008] Furthermore, the first elastic element extends in a horizontal direction, and the connecting element extends in a vertical direction.

[0009] Furthermore, the first elastic element is a spring, and the connecting element is a stud.

[0010] Furthermore, the heating platform includes a base plate and a side plate, the side plate extending from the edge of the base plate, the base plate and the side plate together forming the mounting groove, the heating platform also has a guide groove, the guide groove is located at the edge of the mounting groove, and the guide groove is inclined.

[0011] Furthermore, the heating platform also includes a baffle post, which is fixed to the edge of the mounting groove.

[0012] Furthermore, the base includes a main body and a waste liquid collection structure fixed to the main body. The waste liquid collection structure is provided with a collection tank, which is inclined and located at the end of the guide channel.

[0013] Furthermore, the slide holder also includes a tensioning assembly, which includes a second elastic element, the two ends of which are respectively connected to the base and the mounting base.

[0014] Furthermore, the slide holder also includes a diffuse reflection sensor, which is fixed to the mounting base and faces the heating stage.

[0015] Compared to existing technologies, the slide holder of this utility model has a mounting base that is rotatably mounted on a base. A drive assembly is mounted on the base and connected to the mounting base for transmission. The drive assembly drives the mounting base to rotate relative to the base. A heating stage is mounted on the mounting base via a connecting assembly. A heating film and a vibration motor are mounted between the heating stage and the mounting base. The heating stage has a mounting groove for mounting slides. The heating film heats the slides. The vibration motor drives the heating stage to vibrate. The vibration generated by the vibration motor accelerates the movement of antibody molecules, increases the efficiency of antigen-antibody collision and binding, speeds up the antigen-antibody reaction, and shortens the antigen-antibody reaction time. Attached Figure Description

[0016] Figure 1 This is a perspective view of the slide holder of this utility model;

[0017] Figure 2 for Figure 1 Exploded view of the slide holder;

[0018] Figure 3 for Figure 2 A three-dimensional view of the mounting base for the slide holder;

[0019] Figure 4 for Figure 2 A three-dimensional view of the heating stage of the slide holder;

[0020] Figure 5 for Figure 1 A three-dimensional view of the internal structure of a slide holder;

[0021] Figure 6 for Figure 1 A three-dimensional sectional view of a slide holder;

[0022] Figure 7 for Figure 1 A 3D diagram showing the usage status of a slide holder.

[0023] In the diagram: 10. Base; 11. Main body; 111. Rotating part; 112. Receiving part; 12. Waste liquid collection structure; 120. Collection tank; 20. Drive assembly; 21. Bottom mounting bracket; 22. Drive component; 23. Top mounting bracket; 30. Mounting seat; 31. Main body; 310. Rotating hole; 311. Through hole; 32. Connecting end; 33. Opening; 40. Rotating shaft; 50. Heating film; 60. Vibration motor; 70. Diffuse reflection sensor; 80. Connecting assembly; 81. First elastic element; 82. Connecting element; 90. Tensioning assembly; 91. Second elastic element; 92. Connecting column; 93. Baffle; 100. Heating platform; 101. Base plate; 102. Side plate; 103. Mounting groove; 104. Guide groove; 105. Baffle column; 200. Glass slide. Detailed Implementation

[0024] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0025] It should be noted that when a component is said to be "fixed to" another component, it can be directly on the other component or it can be fixed through another intermediate component. When a component is said to be "connected to" another component, it can be directly connected to the other component or it may be fixed through another intermediate component. When a component is said to be "set on" another component, it can be set directly on the other component or it may be set through another intermediate component. The terms "vertical," "horizontal," "left," "right," and similar expressions used in this document are for illustrative purposes only.

[0026] Unless otherwise defined, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention pertains. The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and / or" as used herein includes any and all combinations of one or more of the associated listed items.

[0027] Please see Figure 1 as well as Figure 2 The slide holder includes a base 10, a drive assembly 20, a mounting base 30, a rotating shaft 40, a heating film 50, a vibration motor 60, a diffuse reflection sensor 70, a connecting assembly 80, a tensioning assembly 90, and a heating stage 100.

[0028] The base 10 includes a main body 11 and a waste liquid collection structure 12 fixed to the main body 11. The main body 11 has a rotating part 111 and a receiving part 112. The rotating part 111 is located on the top of the main body 11, and the main body 11 is rotatably mounted on the mounting base 30 via the rotating part 111. The receiving part 112 is located inside the main body 11 and is used to install the drive assembly 20. The waste liquid collection structure 12 is located on one side of the main body 11 and has a collection tank 120. The collection tank 120 is inclined and is used to collect waste liquid generated during the cleaning and reaction of the heating table 100.

[0029] The drive assembly 20 is used to drive the heating stage 100 to rotate, thereby making it easier to clean reagents during the cleaning process. The drive assembly 20 includes a bottom mounting bracket 21, a drive component 22, and a top mounting bracket 23. The bottom mounting bracket 21 is fixed to the bottom of the receiving part 112, and one end of the drive component 22 is rotatably mounted on the bottom mounting bracket 21. The top mounting bracket 23 is fixed to the mounting base 30, and the other end of the drive component 22 is rotatably mounted on the top mounting bracket 23. In this embodiment, the drive component 22 is an electric push rod. The electric push rod extends to different lengths, which can drive the mounting base 30, the heating stage 100, and the glass slide 200 to rotate around the axis 40 at different angles. Its main function is to make it easier to clean reagents during the cleaning process.

[0030] Please continue reading. Figure 3 The mounting base 30 includes a body 31 and two connecting ends 32 extending from one end of the body 31, with an opening 33 formed between the two connecting ends 32. The opening 33 is used to fix a diffuse reflection sensor 70, which is used to detect whether a glass slide 200 is present on the heating stage 100. The body 31 is provided with a rotating hole 310 and two through holes 311, located on both sides of the rotating hole 310. The axis of the rotating hole 310 is parallel to the axis of the two through holes 311 and is horizontally arranged. The mounting base 30 is rotatably connected to the rotating part 111 through the rotating hole 310, so that the mounting base 30 is rotatably mounted on the body 11 of the base 10. The through holes 311 are used to install the connecting assembly 80, so that the mounting base 30 is connected to the heating stage 100.

[0031] The rotating shaft 40 is used to rotatably connect the main body 11 and the mounting base 30. Specifically, the rotating shaft 40 passes through the rotating part 111 and the rotating hole 310.

[0032] A heating film 50 is installed between the mounting base 30 and the heating stage 100. The heating film 50 heats the heating stage 100 and controls the temperature of the glass slide 200 on the heating stage 100. Specifically, a thermistor is mounted on the heating film 50. There is a groove below the heating stage 100, and the thermistor is placed inside the groove. The groove contains thermally conductive adhesive, mainly for heat conduction and insulation. The main function of the heating film 50 is to provide different reaction temperatures for different reagents to achieve the fastest reaction rate. The main function of the thermistor mounted on it is to monitor the heating temperature in real time when heated.

[0033] The vibration motor 60 is installed between the mounting base 30 and the heating stage 100, and is located below the heating film 50. The vibration motor 60 is fixed on the motor mounting base, which is fixed below the heating stage 100. The main function of the vibration motor 60 is to provide power to the heating stage 100, causing the glass slide 200 on the heating stage 100 to vibrate, thereby increasing the antigen-antibody collision and binding efficiency and shortening the antigen-antibody reaction time.

[0034] The diffuse reflection sensor 70 is fixed to the mounting base 30. The diffuse reflection sensor 70 is used to detect whether there is a glass slide 200 on the heating stage 100.

[0035] Please continue reading. Figure 5 The connecting assembly 80 includes a first elastic element 81 and a connecting element 82. The first elastic element 81 is installed in the through hole 311, and its two ends are fixedly connected to the two connecting elements 82 respectively. The first elastic element 81 is arranged horizontally, and the connecting element 82 is arranged vertically. The connecting element 82 is fixed to the bottom of the heating table 100, connecting the mounting base 30 to the heating table 100. Specifically, the first elastic element 81 is a spring, and the connecting element 82 is a bolt. The height of the connecting element 82 is greater than the distance between the mounting base 30 and the heating table 100, creating a gap between them. This prevents the heating table 100 from touching the mounting base 30 when the vibration motor 60 drives the heating table 100 to vibrate, reducing noise. A limiting pad is installed between the connecting element 82 and the heating table 100. The limiting pad limits the heating table 100, keeping the mounting base 30 at the center of the heating table 100, and preventing collisions between the mounting base 30 and the connecting element 82 during vibration mixing, thus avoiding noise.

[0036] The tensioning assembly 90 includes a second elastic element 91, a connecting post 92, and a baffle 93. Each tensioning assembly 90 has two connecting posts 92 and two baffles 93, with the two connecting posts 92 fixed to the connecting end 32 and the main body 11, respectively. The two ends of the second elastic element 91 are respectively mounted to the connecting post 92 via the baffles 93. In this embodiment, the second elastic element 91 is a spring. When the mounting base 30 and the heating table 100 are flipped, the second elastic element 91 is stretched; when flipped back, the second elastic element 91 contracts. The elastic force of the second elastic element 91 makes it easier for the mounting base 30 to return to its original position when flipped back, preventing gaps between the mounting base 30 and the main body 11 due to processing and assembly errors.

[0037] Please continue reading. Figure 4 The heating platform 100 is provided with a mounting groove 103 for mounting glass slides 200. Specifically, the heating platform 100 includes a base plate 101 and a side plate 102, with the side plate 102 extending from the base plate 101. The base plate 101 and the side plate 102 together form the mounting groove 103. The heating platform 100 also includes three baffles 105, which are fixed to the base plate 101. The three baffles 105 are located on the three sides of the mounting groove 103. The mounting groove 103 is also provided with flow guide channels 104 on both sides. The flow guide channels 104 are inclined and guide the liquid in the mounting groove 103 to the collection tank 120.

[0038] Please continue reading. Figure 6 as well as Figure 7 When using a slide holder, during cell staining, the slide 200 is placed in the mounting slot 103 of the heating stage 100. A baffle 105 at the rear of the heating stage 100 prevents the slide 200 from falling off. Subsequent steps only begin when the diffuse reflection sensor 70 detects the presence of the slide 200. When reagents need to be added to the slide 200, the heating membrane 50 heats up to provide a suitable reaction temperature. At the same time, the vibration motor 60 also starts working, causing the slide 200 to vibrate and quickly mix the reagents, reducing reaction time. When the reaction is complete and the reagents need to be washed, the drive unit 22 rotates the heating stage 100 and the slide 200, allowing them to rinse the reagents from the previous step in the shortest possible time. Then, the slide 200 is rotated back, and the washing solution flows through the guide channel 104 into the collection tank 120 of the waste liquid collection structure 12.

[0039] The slide holder improves cell staining efficiency through vibration mixing and separates the heating stage 100 and mounting base 30 using tensioning components 90, reducing noise during vibration mixing. The slide holder also incorporates a drive component 20 during slide 200 cleaning, resulting in more effective cleaning. Two tensioning components 90 reduce the risk of the heating stage 100 failing to return to its proper position after flipping. Each slide holder is an independent structure, allowing for independent control as needed. The vibration motor 60 drives the heating stage 100 to vibrate, accelerating antibody molecule movement, increasing antigen-antibody collision and binding efficiency, speeding up the antigen-antibody reaction, and shortening the antigen-antibody reaction time.

[0040] The above embodiments only illustrate several implementation methods of this utility model, and their descriptions are relatively specific and detailed, but they should not be construed as limiting the scope of the utility model patent. It should be noted that for those skilled in the art, several modifications and improvements can be made without departing from the concept of this utility model. These are all equivalent modifications and improvements made to the above embodiments based on the essential technology of this utility model, and all of these fall within the protection scope of this utility model.

Claims

1. A slide holder, including a base, characterized in that: The slide holder also includes a drive assembly, a mounting base, a heating film, a vibration motor, a connecting assembly, and a heating stage. The mounting base is rotatably mounted on the base. The drive assembly is mounted on the base and is drively connected to the mounting base. The drive assembly drives the mounting base to rotate relative to the base. The heating stage is mounted on the mounting base via the connecting assembly. The heating film and the vibration motor are mounted between the heating stage and the mounting base. The heating stage has a mounting groove for mounting slides. The heating film heats the slides. The vibration motor drives the heating stage to vibrate.

2. The slide holder according to claim 1, characterized in that: There is a gap between the mounting base and the heating platform.

3. The slide holder according to claim 2, characterized in that: The connecting assembly includes a first elastic element and a connecting element. The first elastic element is installed on the mounting base, and its two ends are respectively fixedly connected to the two connecting elements. The connecting elements are fixed to the heating table.

4. The slide holder according to claim 3, characterized in that: The first elastic element extends horizontally, and the connecting element extends vertically.

5. The slide holder according to claim 4, characterized in that: The first elastic element is a spring, and the connecting element is a stud.

6. The slide holder according to claim 1, characterized in that: The heating platform includes a base plate and a side plate. The side plate extends from the edge of the base plate, and the base plate and the side plate together form the mounting groove. The heating platform is also provided with a flow guide groove, which is located at the edge of the mounting groove and is inclined.

7. The slide holder according to claim 6, characterized in that: The heating platform also includes a baffle post, which is fixed to the edge of the mounting groove.

8. The slide holder according to claim 6, characterized in that: The base includes a main body and a waste liquid collection structure fixed to the main body. The waste liquid collection structure is provided with a collection tank, which is inclined and located at the end of the guide channel.

9. The slide holder according to claim 1, characterized in that: The slide holder also includes a tensioning assembly, which includes a second elastic element, the two ends of which are respectively connected to the base and the mounting base.

10. The slide holder according to claim 1, characterized in that: The slide holder also includes a diffuse reflection sensor, which is fixed to the mounting base and faces the heating stage.

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