Centrifugal device for producing chemical synthetic raw material medicine

By incorporating an adjustable stirring mechanism into the centrifuge unit, the problem of fixed stirring rod position was solved, resulting in more efficient stirring and a stable centrifugation process, thereby improving the production efficiency of chemically synthesized pharmaceutical raw materials.

CN224072270UActive Publication Date: 2026-04-03ZIBO XINHUA-PERRIGO PHARM CO LTD
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
Filing Date
2025-03-31
Publication Date
2026-04-03

AI Technical Summary

Technical Problem

In existing centrifuges used for the production of chemically synthesized pharmaceutical raw materials, the fixed position of the stirring rod results in mediocre stirring effect and low efficiency. Furthermore, the stirring rod is prone to causing disturbances during the centrifugation process, which affects the centrifugation effect and efficiency.

Method used

Multiple stirring mechanisms are employed, including stirring blades and adjusting blocks. The angle and position of the stirring blades are changed by the movement of the adjusting blocks, thereby expanding the stirring range. During centrifugation, the stirring blades are retracted into the rotating tube to reduce disturbance.

Benefits of technology

It improves stirring efficiency and range, reduces disturbances during centrifugation, and ensures centrifugation effect and efficiency.

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Abstract

The utility model relates to the field of medicine manufacturing, in particular to a centrifugal device for producing chemical synthetic raw material medicines, which comprises a processing barrel and a centrifugal barrel arranged in the processing barrel, and a rotating pipe with the same axis as the centrifugal barrel is arranged in the centrifugal barrel; three groups of stirring mechanisms are further included, and the stirring mechanisms are arranged in the rotating pipe and used for changing the stirring range; wherein the stirring mechanism comprises a group of stirring blades and a group of adjusting blocks, the stirring blades are uniformly distributed along the axis of the rotating pipe, a hinge shaft is arranged between the stirring blades and the rotating pipe, a torsional spring is arranged between the hinge shaft and the stirring blades, and the adjusting blocks are connected to the interior of the rotating pipe in a sliding mode and located above the stirring blades; in the medicine stirring process, the stirring area can be changed, the mixing range can be widened, the stirring effect and efficiency can be guaranteed, in the centrifugal operation, the stirring blades can be stored, disturbance formed in the centrifugal process is reduced, and the centrifugal effect and efficiency are guaranteed.
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Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical manufacturing, and in particular to a centrifugal device for the production of chemically synthesized active pharmaceutical ingredients. Background Technology

[0002] Active pharmaceutical ingredients (APIs), also known as active drug components, are substances prepared by chemical synthesis, plant extraction, or biotechnology, but which patients cannot take directly. They are usually processed by adding excipients to make them into drugs that can be used directly.

[0003] A search revealed that the Chinese patent "A Centrifuge Device for the Production of Chemically Synthesized Raw Materials" (CN222358626U) includes a housing with supporting legs bolted to the bottom. A centrifugal mechanism is installed inside the housing, and a cover plate is provided on the top. A first motor is bolted to the top of the cover plate, and the output end of the first motor passes through the cover plate and is connected to a first rotating shaft via a coupling. A fixing rod is bolted to the surface of the first rotating shaft, and a second rotating shaft is rotatably sleeved on the inner wall of the fixing rod. A gear is fixedly sleeved on the surface of the second rotating shaft, and a gear ring meshes with the surface of the gear, with the gear ring engaging with the bottom of the cover plate. The first and second rotating shafts are bolted together, with stirring rods bolted to their surfaces. The first and second rotations drive the corresponding stirring rods to operate, stirring the raw materials to achieve high centrifugation efficiency, improving the mixing efficiency of the raw materials and saving centrifugation time. However, the above method has the following drawbacks in actual use: it uses stirring rods to stir the materials, but the position of the stirring rods is fixed, so the stirring area it covers during the stirring process is fixed, resulting in a general stirring effect and low efficiency. Moreover, after stirring, during centrifugation, the stirring rods are prone to causing disturbances in the material during centrifugation, affecting the centrifugation effect and efficiency.

[0004] Therefore, a centrifugal device for the production of chemically synthesized active pharmaceutical ingredients is proposed to solve the above problems. Utility Model Content

[0005] The purpose of this invention is to provide a centrifugal device for the production of chemically synthesized pharmaceutical raw materials in order to solve the above-mentioned problems, thereby improving the issues of fixed stirring area and easy disturbance of stirring rod during material centrifugation.

[0006] This utility model achieves the above-mentioned objective through the following technical solution: a centrifuge device for the production of chemically synthesized pharmaceutical raw materials, comprising a processing tank and a centrifuge tank disposed inside the processing tank, wherein a rotating tube with the same axis as the centrifuge tank is disposed inside the centrifuge tank; further comprising a stirring mechanism, wherein the number of stirring mechanisms is three sets, wherein the stirring mechanism is disposed inside the rotating tube and is used to change the stirring range; wherein, the stirring mechanism comprises a set of stirring blades evenly distributed along the axis of the rotating tube and a set of adjusting blocks, wherein a hinge shaft is disposed between the stirring blades and the rotating tube, a torsion spring is disposed between the hinge shaft and the stirring blades, and the adjusting blocks are slidably connected to the inside of the rotating tube and are positioned above the stirring blades.

[0007] Preferably, the stirring blade and the side opposite to the adjusting block are both provided with a chamfer.

[0008] Preferably, the rotating tube has three sliding discs installed inside, and a magnetic ring is fixedly sleeved on the outer side of each sliding disc. The outer side of the magnetic ring is magnetically connected to one side of the adjusting block, and two connecting rods are installed between two adjacent sliding discs.

[0009] Preferably, a first motor is installed on the top of the processing barrel, and the output shaft of the first motor is connected to a branch pipe fixedly connected to the rotating tube via a coupling. An electric push rod extending into the rotating tube is installed inside the branch pipe, and the electric push rod is fixedly connected to the outer side of the top sliding plate.

[0010] Preferably, a second motor is installed at the bottom of the processing barrel, and the output shaft of the second motor is fixedly connected to the bottom of the centrifuge barrel via a coupling.

[0011] Preferably, a set of guide wheels is installed on the outside of the centrifuge barrel, and the guide wheels are rotatably connected to the inside of the processing barrel.

[0012] Preferably, a set of stirring bars is fixedly installed on the outside of the rotating tube, and a set of mixing holes is opened inside the stirring blade.

[0013] The beneficial effects of this utility model are:

[0014] 1. By setting an adjustment block, the adjustment block can be used to abut against the stirring blade, causing its setting angle to change. Combined with the torsion spring that drives it to return to its original position, the stirring blade can be made to swing when the adjustment block moves up and down repeatedly, thereby changing the stirring area in real time, increasing the stirring range, and ensuring stirring effect and efficiency.

[0015] 2. By setting up a rotating tube, the stirring blades can be completely retracted into the rotating tube after the stirring blades have finished their operation. The rotating tube is aligned with the axis of the centrifuge tank, so that the rotating tube is located at the center of the vortex during centrifugation. This effectively reduces the disturbances generated during centrifugation, thus ensuring the centrifugation effect and efficiency. Attached Figure Description

[0016] Figure 1 This is a schematic diagram of the structure of this utility model;

[0017] Figure 2 This is a cross-sectional schematic diagram of the processing barrel and centrifuge barrel of this utility model;

[0018] Figure 3 for Figure 2 Enlarged view of A in the middle;

[0019] Figure 4 This is a schematic diagram of the hinge shaft and torsion spring of this utility model.

[0020] In the diagram: 100, processing tank; 200, centrifuge tank; 300, rotating tube; 310, sliding disc; 311, magnetic ring; 320, electric push rod; 330, stirring bar; 400, stirring mechanism; 410, stirring blade; 411, hinge shaft; 412, torsion spring; 413, mixing hole; 420, adjusting block. Detailed Implementation

[0021] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0022] In practical implementation: such as Figure 1-4 As shown, a centrifuge device for the production of chemically synthesized pharmaceutical raw materials includes a processing tank 100 and a centrifuge tank 200 disposed inside the processing tank 100. A rotating tube 300 with the same axis as the centrifuge tank 200 is disposed inside the centrifuge tank 200. It also includes a stirring mechanism 400, of which there are three sets. The stirring mechanism 400 is disposed inside the rotating tube 300 and is used to change the stirring range. The stirring mechanism 400 includes a set of stirring blades 410 evenly distributed along the axis of the rotating tube 300 and a set of adjusting blocks 420. A hinge shaft 411 is disposed between the stirring blades 410 and the rotating tube 300. A torsion spring 412 is disposed between the hinge shaft 411 and the stirring blades 410. The adjusting blocks 420 are slidably connected to the inside of the rotating tube 300 and are located above the stirring blades 410.

[0023] like Figure 3 As shown, both the stirring blade 410 and the adjusting block 420 have chamfers on their opposite sides.

[0024] The user can open the feed cover on the processing tank 100 and then introduce the material into the centrifuge tank 200 through the feed inlet. Then, the user can drive the rotating tube 300 to rotate and mix the material. During the mixing process, the user can drive the adjusting block 420 to move downward. At this time, the chamfer on the adjusting block 420 will abut against the chamfer on the stirring blade 410. Then, the stirring blade 410 will be pressed and rotate along the hinge shaft 411. At this time, the stirring blade 410 will move partially to the outside of the rotating tube 300 to mix the material. The angle of the stirring blade 410 is affected by the downward movement of the adjusting block 420. During the adjustment of the stirring blade 410, the torsion spring 412 is always in a deformed and compressed state. As the adjusting block 420 moves up and down repeatedly, the stirring blade 410 will also swing repeatedly in the centrifuge tank 200, thereby changing the mixing area in real time and expanding the mixing range.

[0025] After the stirring operation is completed, the user can reset the adjusting block 420. Then, driven by the deformation force of the torsion spring 412, the stirring blade 410 can move back to its original position to complete the storage process. Afterward, the user can drive the centrifuge tank 200 to operate and perform centrifugation. During the centrifugation process, since the stirring blade 410 is in the stored state and the rotating tube 300 is aligned with the axis of the centrifuge tank 200, the rotating tube 300 is located at the center of the vortex during the centrifugation process. This can effectively reduce the disturbance generated during the centrifugation process, thereby ensuring the centrifugation effect and efficiency.

[0026] like Figure 2 and Figure 3 As shown, three sliding discs 310 are installed inside the rotating tube 300. A magnetic ring 311 is fixedly sleeved on the outside of the sliding disc 310. The outside of the magnetic ring 311 is magnetically connected to one side of the adjusting block 420. Two connecting rods are installed between two adjacent sliding discs 310.

[0027] When the adjustment block 420 needs to be driven, the user can drive the sliding disk 310 to move. Then the sliding disk 310 will drive the magnetic ring 311 to follow the movement. Using magnetic attraction, the adjustment block 420 will move synchronously with the magnetic ring 311.

[0028] like Figure 1 and Figure 2 As shown, a first motor is installed on the top of the processing barrel 100. The output shaft of the first motor is connected to a branch pipe fixedly connected to the rotating tube 300 via a coupling. An electric push rod 320 extending into the rotating tube 300 is installed inside the branch pipe. The electric push rod 320 is fixedly connected to the outer side of the top sliding plate 310.

[0029] Starting the first motor drives the branch pipe to rotate, which in turn drives the rotating pipe 300 to rotate, thereby driving the stirring blade 410 to mix the materials. The electric push rod 320 drives the sliding disk 310 and the magnetic ring 311 to move up and down, thus causing the adjusting block 420 to change position.

[0030] It should be noted that the electric actuator 320 used in this application is powered by a built-in power supply.

[0031] like Figure 1 and Figure 2 As shown, a second motor is installed at the bottom of the processing barrel 100, and the output shaft of the second motor is fixedly connected to the bottom of the centrifuge barrel 200 through a coupling.

[0032] The centrifuge tank 200 can be driven by the second motor to perform centrifugation.

[0033] like Figure 2 As shown, a set of guide wheels is installed on the outside of the centrifuge tank 200, and the guide wheels are rotatably connected to the inside of the processing tank 100.

[0034] The use of guide wheels makes the centrifuge tank 200 rotate more smoothly and stably, reducing the occurrence of unexpected deviations.

[0035] like Figure 2 , Figure 3 and Figure 4 As shown, a set of stirring bars 330 are fixedly installed on the outside of the rotating tube 300, and a set of mixing holes 413 are opened inside the stirring blade 410.

[0036] By using the stirring bar 330, the material outside the rotating tube 300 can be mixed during the rotation of the rotating tube 300, which helps the stirring blade 410 achieve a better mixing effect. By using the mixing hole 413, some material can flow along the mixing hole 413 during the movement of the stirring blade 410, thereby improving the mixing effect of the material in the centrifuge tank 200.

[0037] Working Principle: The user can open the feed cover on the processing tank 100 and then introduce the material into the centrifuge tank 200 through the feed inlet. Next, the first motor can be started to drive the rotating tube 300 to rotate, mixing the material. During the mixing process, the user can drive the electric push rod 320, causing the corresponding sliding disc 310 and connecting rod to move synchronously, causing the adjusting block 420 to move downwards. At this time, the chamfer on the adjusting block 420 will abut against the chamfer on the stirring blade 410, and then the stirring blade 410 will rotate along the hinge shaft 411 under pressure. The stirring blade 410 will then partially move to the outside of the rotating tube 300 to mix the material. The angle of the stirring blade 410 is affected by the downward movement of the adjusting block 420. Therefore, during the repeated up-and-down movement of the adjusting block 420, the stirring blade 410 will also repeatedly oscillate within the centrifuge tank 200, thus changing the mixing area in real time and expanding the mixing range. After the mixing operation is completed, the user can reset the adjusting block 420. Subsequently, driven by the deformation force of the torsion spring 412, the stirring blade 410 can move back to its original position to complete the storage process. Then, the user can start the second motor to drive the centrifuge tank 200 to operate and perform centrifugation. During the centrifugation process, since the stirring blade 410 is in the stored state and the rotating tube 300 is aligned with the axis of the centrifuge tank 200, the rotating tube 300 is located at the center of the vortex during the centrifugation process, which can effectively reduce the disturbance generated during the centrifugation process, thereby ensuring the centrifugation effect and efficiency. After the centrifugation operation is completed, the user can perform liquid suction operation along the feed port on the processing tank 100, or discharge materials through the discharge pipes on the centrifuge tank 200 and the processing tank 100 according to the usage requirements. The entire device can change the stirring area and increase the mixing range during the material stirring process, ensuring the stirring effect and efficiency. Moreover, during the centrifugation operation, the stirring blade 410 can be stored to reduce the disturbance generated during the centrifugation process, ensuring the centrifugation effect and efficiency.

[0038] Furthermore, it should be understood that although this specification describes embodiments, not every embodiment contains only one independent technical solution. This narrative style is merely for clarity. Those skilled in the art should consider the specification as a whole, and the technical solutions in each embodiment can also be appropriately combined to form other embodiments that can be understood by those skilled in the art.

Claims

1. A centrifuge device for producing chemically synthesized pharmaceutical raw materials, characterized in that, include: The processing barrel (100) and the centrifuge barrel (200) disposed inside it, wherein the centrifuge barrel (200) is provided with a rotating tube (300) with the same axis as its axis. It also includes a stirring mechanism (400), of which there are three sets. The stirring mechanism (400) is disposed inside the rotating tube (300) and is used to change the stirring range. The stirring mechanism (400) includes a set of stirring blades (410) evenly distributed along the axis of the rotating tube (300) and a set of adjusting blocks (420). A hinge shaft (411) is provided between the stirring blades (410) and the rotating tube (300), and a torsion spring (412) is provided between the hinge shaft (411) and the stirring blades (410). The adjusting blocks (420) are slidably connected to the interior of the rotating tube (300) and are located above the stirring blades (410).

2. The centrifuge device for producing chemically synthesized pharmaceutical raw materials according to claim 1, characterized in that: The stirring blade (410) and the adjusting block (420) are both provided with chamfers on the opposite side.

3. The centrifuge device for producing chemically synthesized pharmaceutical raw materials according to claim 1, characterized in that: The rotating tube (300) has three sliding discs (310) installed inside. A magnetic ring (311) is fixedly sleeved on the outside of the sliding disc (310). The outside of the magnetic ring (311) is magnetically connected to one side of the adjusting block (420). Two connecting rods are installed between two adjacent sliding discs (310).

4. The centrifuge device for producing chemically synthesized pharmaceutical raw materials according to claim 1, characterized in that: The top of the processing barrel (100) is equipped with a first motor. The output shaft of the first motor is connected to a branch pipe fixedly connected to the rotating tube (300) via a coupling. An electric push rod (320) extending into the rotating tube (300) is installed inside the branch pipe. The electric push rod (320) is fixedly connected to the outside of the top sliding plate (310).

5. A centrifuge device for producing chemically synthesized pharmaceutical raw materials according to claim 1, characterized in that: A second motor is installed at the bottom of the processing barrel (100), and the output shaft of the second motor is fixedly connected to the bottom of the centrifuge barrel (200) via a coupling.

6. A centrifuge device for producing chemically synthesized pharmaceutical raw materials according to claim 1, characterized in that: A set of guide wheels is installed on the outside of the centrifuge barrel (200), and the guide wheels are rotatably connected to the inside of the processing barrel (100).

7. A centrifuge device for producing chemically synthesized pharmaceutical raw materials according to claim 1, characterized in that: A set of stirring bars (330) is fixedly installed on the outside of the rotating tube (300), and a set of mixing holes (413) is opened inside the stirring blade (410).

Citation Information

Patent Citations

  • Centrifugal device for producing chemical synthetic raw material medicine

    CN222358626U