Variable-frequency ultrasonic cell crusher
By designing limiting and guiding structures in the variable frequency ultrasonic cell disruptor, the problem of inaccurate beaker placement was solved, and the ultrasonic probe was aligned with the center of the beaker, improving cell disruption efficiency and placement convenience.
Patent Information
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- HEOS (NANJING) SCI INSTR CO LTD
- Filing Date
- 2025-05-08
- Publication Date
- 2026-04-17
AI Technical Summary
In existing variable frequency ultrasonic cell disruptors, the beaker is not placed accurately enough, causing the ultrasonic probe and the center of the beaker to be out of line, which affects the disruption efficiency.
A structure including a placement plate, a limiting groove, a limiting block, a limiting plate, and a guide groove was designed. Through the cooperation of the limiting shaft and the drive shaft, the beaker can be accurately positioned in the center of the placement plate, and the ultrasonic device is aligned with the center of the beaker, thereby improving the crushing efficiency.
Through the design of limiting and guiding structures, the beaker can be accurately positioned, and the ultrasonic probe is aligned with the center of the beaker, which significantly improves the efficiency of cell disruption and the convenience of placement.
Smart Images
Figure 1
Abstract
Description
Technical Field
[0001] This utility model relates to the field of ultrasonic equipment, specifically a frequency conversion ultrasonic cell disruptor. Background Technology
[0002] A variable frequency ultrasonic cell disruptor is an experimental device that uses the principle of ultrasonic vibration to break down cells and tissues. It generates high-frequency vibrations through an ultrasonic transducer, which act on cells or tissues, thereby causing the cell membrane to rupture and releasing the cell's components. Variable frequency technology allows the device's operating frequency to vary within a certain range, optimizing the ultrasonic effect and improving cell disruption efficiency.
[0003] Variable frequency ultrasonic cell disruptors utilize the cavitation effect generated by high-frequency ultrasound in liquids to subject cell membranes to intense mechanical pressure and shear force, causing them to rupture. The variable frequency system allows the operating frequency of the equipment to fluctuate within a certain range, which reduces the cell's adaptability to a fixed frequency and improves the cell disruption effect. Since heat is generated during ultrasonic disruption, the equipment is usually equipped with a temperature control system to prevent the sample from degrading due to overheating and to maintain the integrity of the cell contents.
[0004] In the existing technology, during the use of the frequency conversion ultrasonic cell disruptor, the beaker is simply placed on the support plate. The placement of the beaker is not accurate enough, which causes the ultrasonic probe on the ultrasonic cell disruptor to be out of line with the center of the beaker, thus affecting the disruption efficiency. Utility Model Content
[0005] Therefore, the purpose of this utility model is to provide a variable frequency ultrasonic cell disruptor to solve the technical problems mentioned above in the background art.
[0006] To achieve the above objectives, the present invention provides the following technical solution: a variable frequency ultrasonic cell pulverizer, comprising a pulverizer body, a placement plate, and an ultrasonic device, wherein the placement plate is movably installed inside the pulverizer body, and the ultrasonic device is installed inside the pulverizer body and is located at the upper end of the placement plate.
[0007] The upper end of the placement plate is provided with multiple sets of limiting grooves, each set of limiting grooves is movably installed with a limiting block, each set of limiting blocks is movably installed with a limiting plate, each set of limiting grooves is movably installed with a limiting shaft, and the outer wall of each set of limiting shafts is threadedly connected to the inner wall of each set of limiting blocks.
[0008] The main body of the crusher is equipped with an operating chamber, and a reserved slot is opened inside the operating chamber. One end of a set of limiting shafts is movably connected to the reserved slot.
[0009] By adopting the above technical solution, the problem of centering the beaker is solved. The beaker is placed on the upper part of the placement plate, and the placement plate moves upward, driving multiple sets of limiting shafts to rotate, thereby driving multiple sets of limiting blocks to move, which in turn drives multiple sets of limiting plates to move. The multiple sets of limiting plates successively fit against one side of the outer wall of the beaker, pushing the beaker to the center of the placement plate, so that the ultrasonic device on the ultrasonic cell crusher and the center of the beaker are on a straight line, thereby improving the crushing efficiency.
[0010] The present invention is further configured such that two sets of sliding grooves are provided inside the operating chamber, and a drive shaft is movably installed inside each of the two sets of sliding grooves. The two sets of drive shafts are connected by a synchronous belt, and the outer walls of the two sets of drive shafts are threadedly connected to the inner wall of the placement plate.
[0011] Preferably, the drive motor is started, which drives a set of drive shafts to rotate. The two sets of drive shafts are connected by a synchronous belt, and the two sets of drive shafts rotate.
[0012] The present invention is further configured such that a control screen is installed on the outer wall of the main body of the crusher, and the control screen is electrically connected to the drive motor and the ultrasonic device.
[0013] Preferably, the operator starts the drive motor and ultrasonic device via a control panel.
[0014] The present invention is further configured such that a toothed plate is installed on the inner wall of the reserved groove, and a set of the limiting shafts extends into one end of the reserved groove and is equipped with a limiting gear, and the limiting gear is meshed with the toothed plate.
[0015] Preferably, the limiting gear is displaced inside the reserved slot, moves to one side of the toothed plate, meshes with the toothed plate, and rotates.
[0016] The present invention is further configured such that each of the multiple sets of limiting shafts is equipped with a limiting bevel gear at one end, and a toothed ring is movably installed inside the placement plate, and the multiple sets of limiting bevel gears are meshed with the toothed ring.
[0017] Preferably, a set of limiting shafts rotates, which in turn drives a set of limiting bevel gears to rotate. All sets of limiting bevel gears are meshed with the gear ring. Thus, a set of limiting bevel gears drives the gear ring to rotate, and the gear ring drives the remaining sets of limiting bevel gears to rotate. The multiple sets of limiting bevel gears then drive the multiple sets of limiting shafts to rotate.
[0018] The present invention is further configured such that each of the multiple sets of limiting blocks is equipped with an installation column at its upper end, and the outer wall of the multiple sets of installation columns is threadedly connected to the inner wall of the multiple sets of limiting plates.
[0019] Preferably, multiple sets of limiting blocks move, causing multiple sets of mounting columns to shift, thereby causing multiple sets of limiting plates to shift.
[0020] The present invention is further configured such that one end of each of the multiple sets of limiting plates is arc-shaped, and the outer wall of each of the multiple sets of limiting plates is covered with a rubber pad layer.
[0021] Preferably, multiple sets of limiting plates are respectively attached to one side of the outer wall of the beaker, and the rubber pad layer is provided to protect the beaker.
[0022] The present invention is further configured such that guide posts are symmetrically installed on the outer walls of the multiple sets of limiting plates, and the outer walls of the multiple sets of guide posts are covered with a rubber layer; multiple sets of guide grooves are symmetrically opened on the inner walls of the multiple sets of limiting grooves, and the multiple sets of guide grooves are inclined; the outer walls of the multiple sets of guide posts are respectively movably connected to the inner walls of the multiple sets of guide grooves, and the inner walls of the multiple sets of guide grooves are covered with a rubber layer.
[0023] Preferably, multiple sets of limiting plates are displaced, causing multiple sets of guide posts to move within multiple sets of guide grooves, so that one end of each set of limiting plates moves out of the multiple sets of limiting grooves. The rubber layer enhances the stability of the guide posts within the guide grooves.
[0024] In summary, the present invention has the following main advantages:
[0025] 1. This utility model solves the problem of centering the beaker by setting up a placement plate, limiting blocks, and a limiting plate. The beaker is placed on the upper part of the placement plate, and the placement plate moves upward, driving multiple sets of limiting shafts to rotate, thereby driving multiple sets of limiting blocks to move, which in turn drives multiple sets of limiting plates to move. The multiple sets of limiting plates successively fit against one side of the outer wall of the beaker, pushing the beaker to the center of the placement plate, so that the ultrasonic device on the ultrasonic cell crusher and the center of the beaker are on a straight line, thereby improving the crushing efficiency.
[0026] 2. This utility model solves the problem of beaker placement being obstructed by setting limiting grooves, guide grooves, limiting plates, and guide pillars. When the staff places the beaker, multiple sets of limiting plates are placed inside multiple sets of limiting grooves, avoiding obstruction of beaker placement. After the beaker is placed, when the placement plate moves upward, multiple sets of limiting plates move towards the beaker, thereby driving multiple sets of guide pillars to move. Multiple sets of guide pillars are set inside multiple sets of guide grooves, and the multiple sets of guide grooves are inclined, so that one end of each set of limiting plates moves out of the multiple sets of limiting grooves, improving the convenience of beaker placement. Attached Figure Description
[0027] Figure 1 This is a schematic diagram of the main body of the pulverizer in this utility model;
[0028] Figure 2 This is a side sectional view of the main body of the crusher in this utility model;
[0029] Figure 3 This is a schematic diagram of the internal structure of the pulverizer body in this utility model;
[0030] Figure 4 This is a schematic diagram of the placement plate in this utility model;
[0031] Figure 5 This is a schematic diagram of the internal structure of the placement plate in this utility model.
[0032] Explanation of reference numerals in the attached figures:
[0033] 1. Crusher body; 2. Control chamber; 3. Control panel; 4. Reserved slot; 5. Toothed plate; 6. Slide groove; 7. Drive motor; 8. Drive shaft; 9. Placement plate; 10. Limiting slot; 11. Guide slot; 12. Limiting shaft; 13. Limiting gear; 14. Limiting bevel gear; 15. Gear ring; 16. Limiting block; 17. Mounting column; 18. Limiting plate; 19. Guide column; 20. Ultrasonic device. Detailed Implementation
[0034] The technical solutions of the present invention will be clearly and completely described below with reference to the accompanying drawings. The embodiments described below with reference to the accompanying drawings are exemplary and are only used to explain the present invention, and should not be construed as limiting the present invention.
[0035] The embodiments of this utility model will be described below based on its overall structure.
[0036] A variable frequency ultrasonic cell disruptor, such as Figure 1 - Figure 5 As shown, it includes a crusher body 1, a placement plate 9 and an ultrasonic device 20. The placement plate 9 is movably installed inside the crusher body 1, and the ultrasonic device 20 is installed inside the crusher body 1, with the ultrasonic device 20 located at the upper end of the placement plate 9.
[0037] The upper end of the placement plate 9 has multiple sets of limiting grooves 10, each set of limiting grooves 10 has a limiting block 16 movably installed inside, each set of limiting block 16 has a limiting plate 18 movably installed at its upper end, each set of limiting grooves 10 has a limiting shaft 12 movably installed inside, and the outer wall of each set of limiting shaft 12 is threadedly connected to the inner wall of each set of limiting block 16. When the multiple sets of limiting shaft 12 rotate, they drive the multiple sets of limiting blocks 16 to move, thereby driving the multiple sets of limiting plates 18 to move.
[0038] The main body 1 of the crusher is equipped with an operating chamber 2. The operating chamber 2 has a reserved slot 4, and one end of a set of limiting shafts 12 is movably connected to the reserved slot 4.
[0039] Please see Figure 2 - Figure 3 The operating chamber 2 has two sets of sliding grooves 6 inside, and a drive shaft 8 is movably installed inside each set of sliding grooves 6. The two sets of drive shafts 8 are connected by a synchronous belt. The outer walls of the two sets of drive shafts 8 are threaded to the inner wall of the placement plate 9. When the drive motor 7 starts, it drives one set of drive shafts 8 to rotate. The two sets of drive shafts 8 are connected by a synchronous belt, and the two sets of drive shafts 8 rotate.
[0040] Please see Figure 1 - Figure 3 The main body 1 of the crusher is equipped with a control panel 3, which is electrically connected to the drive motor 7 and the ultrasonic device 20. The operator starts the drive motor 7 and the ultrasonic device 20 through the control panel 3.
[0041] Please see Figure 2 - Figure 5 A toothed plate 5 is installed on the inner wall of the reserved groove 4. A set of limiting shafts 12 extends into the reserved groove 4 and a limiting gear 13 is installed at one end. The limiting gear 13 meshes with the toothed plate 5. The limiting gear 13 moves inside the reserved groove 4. The limiting gear 13 moves to one side of the toothed plate 5 and meshes with the toothed plate 5. The limiting gear 13 rotates.
[0042] Please see Figure 3 - Figure 5 Each of the multiple sets of limiting shafts 12 has a limiting bevel gear 14 installed at one end. A gear ring 15 is movably installed inside the placement plate 9, and the multiple sets of limiting bevel gears 14 are all meshed with the gear ring 15. When one set of limiting shafts 12 rotates, it drives one set of limiting bevel gears 14 to rotate. Since the multiple sets of limiting bevel gears 14 are all meshed with the gear ring 15, one set of limiting bevel gears 14 drives the gear ring 15 to rotate, and the gear ring 15 drives the remaining multiple sets of limiting bevel gears 14 to rotate. The multiple sets of limiting bevel gears 14 respectively drive the multiple sets of limiting shafts 12 to rotate.
[0043] Please see Figure 3 - Figure 5 Each of the multiple sets of limiting blocks 16 has an installation post 17 installed on its upper end, and the outer wall of the multiple sets of installation posts 17 is threadedly connected to the inner wall of the multiple sets of limiting plates 18. When the multiple sets of limiting blocks 16 move, they drive the multiple sets of installation posts 17 to move, thereby driving the multiple sets of limiting plates 18 to move.
[0044] Please see Figure 3 - Figure 5 Each of the multiple sets of limiting plates 18 has an arc-shaped end, and each of the multiple sets of limiting plates 18 has a rubber pad attached to its outer wall. The multiple sets of limiting plates 18 are respectively attached to one side of the outer wall of the beaker, and the rubber pad is provided to protect the beaker.
[0045] Please see Figure 4 - Figure 5 Multiple sets of limiting plates 18 are symmetrically equipped with guide posts 19 on their outer walls, and the outer walls of multiple sets of guide posts 19 are covered with a rubber layer. Multiple sets of limiting grooves 10 are symmetrically opened with multiple sets of guide grooves 11 on their inner walls, and the multiple sets of guide grooves 11 are inclined. The outer walls of multiple sets of guide posts 19 are movably connected to the inner walls of multiple sets of guide grooves 11, and the inner walls of multiple sets of guide grooves 11 are covered with a rubber layer. When multiple sets of limiting plates 18 are displaced, they drive multiple sets of guide posts 19 to move within multiple sets of guide grooves 11, so that one end of multiple sets of limiting plates 18 moves out of multiple sets of limiting grooves 10. The rubber layer improves the stability of the guide posts inside the guide grooves.
[0046] The working principle of this utility model is as follows: When the operator uses the variable frequency ultrasonic cell crusher, the operator places the beaker on the upper end of the placement plate 9, and then starts the drive motor 7 to drive a set of drive shafts 8 to rotate. The two sets of drive shafts 8 are connected by a synchronous belt. The outer walls of the two sets of drive shafts 8 are threaded to the inner wall of the placement plate 9. The placement plate 9 moves upward, which drives the beaker to move upward and drives the limiting gear 13 to move inside the reserved groove 4. The limiting gear 13 moves to one side of the toothed plate 5 and meshes with the toothed plate 5. The limiting gear 13 rotates, which drives a set of limiting shafts 12 to rotate.
[0047] When a set of limiting shafts 12 rotates, it drives a set of limiting bevel gears 14 to rotate. All sets of limiting bevel gears 14 are meshed with the gear ring 15. Therefore, one set of limiting bevel gears 14 drives the gear ring 15 to rotate, and the gear ring 15 drives the remaining sets of limiting bevel gears 14 to rotate. Each set of limiting bevel gears 14 drives a set of limiting shafts 12 to rotate. The outer walls of the multiple sets of limiting shafts 12 are threadedly connected to the inner walls of multiple sets of limiting blocks 16. Therefore, the multiple sets of limiting blocks 16 are displaced, thereby driving the multiple sets of limiting shafts 12 to rotate. The mounting column 17 is displaced, which in turn drives multiple sets of limiting plates 18 to move, and then drives multiple sets of guide columns 19 to move within multiple sets of guide grooves 11. This causes one end of each set of limiting plates 18 to move out of the multiple sets of limiting grooves 10, and one end of each set of limiting plates 18 to adhere to one side of the outer wall of the beaker, pushing the beaker to the center of the placement plate 9. The placement plate 9 continues to move upward, causing one end of the ultrasonic device 20 to enter the beaker. The ultrasonic device 20 is then activated to perform cell crushing and pulverizing operations, improving the cell disruption efficiency.
[0048] Although embodiments of the present invention have been shown and described, these specific embodiments are merely explanations of the present invention and are not intended to limit the invention. The specific features, structures, materials, or characteristics described may be combined in any suitable manner in one or more embodiments or examples. After reading this specification, those skilled in the art may make modifications, substitutions, and variations to the embodiments as needed without departing from the principles and spirit of the present invention, provided that such modifications, substitutions, and variations are within the scope of the claims of the present invention and are protected by patent law.
Claims
1. A frequency-variable ultrasonic cell disrupter comprising a disrupter main body (1), a placement plate (9), and an ultrasonic device (20), characterized by: The crusher body (1) is movably installed with a placement plate (9), and the crusher body (1) is equipped with an ultrasonic device (20), which is located at the upper end of the placement plate (9). The upper end of the placement plate (9) is provided with multiple sets of limiting grooves (10), and each set of limiting grooves (10) is movably installed with a limiting block (16). Each set of limiting blocks (16) is movably installed with a limiting plate (18) at its upper end. Each set of limiting grooves (10) is movably installed with a limiting shaft (12), and the outer wall of each set of limiting shafts (12) is threadedly connected to the inner wall of each set of limiting blocks (16). The main body (1) of the crusher is provided with an operating chamber (2), and a reserved slot (4) is provided inside the operating chamber (2), and one end of a set of limiting shafts (12) is movably connected to the reserved slot (4).
2. The variable frequency ultrasonic cell disrupter of claim 1, wherein: The operating chamber (2) has two sets of sliding grooves (6) inside. A drive shaft (8) is movably installed inside each of the two sets of sliding grooves (6), and the two sets of drive shafts (8) are connected by a synchronous belt. The outer walls of the two sets of drive shafts (8) are threaded to the inner wall of the placement plate (9).
3. The variable frequency ultrasonic cell disrupter of claim 2, wherein: The main body (1) of the crusher is equipped with a control panel (3) on its outer wall, and the control panel (3) is electrically connected to the drive motor (7) and the ultrasonic device (20).
4. The variable frequency ultrasonic cell disrupter of claim 1, wherein: The inner wall of the reserved groove (4) is equipped with a toothed plate (5), and a set of limiting shafts (12) extends into one end of the reserved groove (4) and is equipped with a limiting gear (13), and the limiting gear (13) meshes with the toothed plate (5).
5. The frequency variable ultrasonic cell disrupter according to claim 1, wherein: Each of the multiple sets of limiting shafts (12) is equipped with a limiting bevel gear (14) at one end. A toothed ring (15) is movably installed inside the placement plate (9), and the multiple sets of limiting bevel gears (14) are meshed with the toothed ring (15).
6. The frequency variable ultrasonic cell disrupter according to claim 1, wherein: Each of the multiple sets of limiting blocks (16) has an installation post (17) installed on its upper end, and the outer wall of the multiple sets of installation posts (17) is threadedly connected to the inner wall of the multiple sets of limiting plates (18).
7. The frequency variable ultrasonic cell disrupter according to claim 1, wherein: One end of each of the multiple sets of limiting plates (18) is arc-shaped, and the outer wall of each set of limiting plates (18) is covered with a rubber pad layer.
8. The frequency variable ultrasonic cell disrupter according to claim 1, wherein: The outer walls of the multiple sets of limiting plates (18) are symmetrically equipped with guide posts (19), and the outer walls of the multiple sets of guide posts (19) are covered with rubber layers.
9. A frequency variable ultrasonic cell disrupter according to claim 8, wherein: Multiple sets of guide grooves (11) are symmetrically opened on the inner walls of the multiple sets of limiting grooves (10), and the multiple sets of guide grooves (11) are inclined.
10. The frequency variable ultrasonic cell disrupter according to claim 9, wherein: The outer walls of the multiple sets of guide posts (19) are movably connected to the inner walls of the multiple sets of guide grooves (11), and the inner walls of the multiple sets of guide grooves (11) are all covered with a rubber layer.