Alternate uncovering mechanism and alternate uncovering liquid taking structure

The alternating capping mechanism enables rapid unscrewing of sample tube caps and simultaneous liquid processing, solving the inefficiency problem caused by unscrewing caps one by one and improving the efficiency of cell culture and immunoassay.

CN224148067UActive Publication Date: 2026-04-21SHANGHAI LECHEN BIOLOGICAL SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Utility models(China)
Current Assignee / Owner
SHANGHAI LECHEN BIOLOGICAL SCI & TECH
Filing Date
2025-04-23
Publication Date
2026-04-21

AI Technical Summary

Technical Problem

In cell culture and immunoassay, unscrewing the caps of sample tubes one by one results in low processing efficiency. Subsequent addition of processing reagents or transfer of liquid to the constant temperature module requires waiting, which affects work efficiency.

Method used

An alternating cap-opening mechanism is adopted, including a rotary motor, a rotating support, and a position sensor. The rotating support has sample tube clamps at both ends. The rotary motor is controlled by the position sensor to achieve the interchange of sample tube clamp positions. Combined with the clamping detection mechanism and the robotic arm, the cap-opening and liquid extraction/injection operations are performed synchronously.

Benefits of technology

It enables the simultaneous operation of quickly unscrewing the sample tube cap and handling the liquid, improving the continuity and efficiency of the processing.

✦ Generated by Eureka AI based on patent content.

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Abstract

The utility model discloses an alternate uncovering mechanism and an alternate uncovering liquid taking structure, and relates to the technical field of cell culture equipment. The alternate uncovering mechanism comprises a rotating motor, a rotating support and a position sensor, the rotating support is linear, sample tube clamping positions are arranged at the two ends of the rotating support respectively, and the sample tube clamping positions located at the two ends of the rotating support can synchronously clamp sample tubes for uncovering and liquid extraction / injection operation; the operation of adding a treatment reagent or pumping liquid to transfer a sample into the constant-temperature module can be synchronously performed when the bottle cap is unscrewed, so that the continuity of treatment operation is high, and the working efficiency is improved.
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Description

Technical Field

[0001] This application relates to the field of cell culture equipment technology, specifically to an alternating cap opening mechanism and an alternating cap opening liquid extraction structure. Background Technology

[0002] In the fields of cell culture and immunoassay, multi-well plate seeding is a fundamental and crucial experimental procedure. Cell culture generally requires the use of sample tubes. Before culturing the liquid sample in the sample tube, it is necessary to mix it thoroughly and open the cap. Then, processing reagents are added before transferring it to the incubator. Opening the caps of the sample tubes one by one results in low processing efficiency at this stage. Subsequent operations such as adding processing reagents or transferring samples to the incubator require waiting, further impacting work efficiency. Utility Model Content

[0003] This application provides an alternating cap opening mechanism and an alternating cap opening liquid extraction structure, which can solve the technical problem that the current sample tube caps are unscrewed one by one, resulting in low processing efficiency in this step. Subsequent operations such as adding processing reagents or extracting and transferring samples to the constant temperature module require waiting, which affects the inoculation efficiency.

[0004] This application provides an alternating cap opening mechanism, which includes a rotary motor, a rotating bracket, and a position sensor. The rotary motor has a rotating shaft, the rotating bracket is connected to the rotating shaft, and the position sensor is fixed on the rotary motor and disposed adjacent to the rotating shaft. The position sensor detects the position of the rotating bracket, which is linear and has sample tube clamping positions at both ends. The position sensor is electrically connected to the rotary motor. When the rotary motor is turned on, the position sensor controls the rotary motor to stop when it detects the rotating bracket.

[0005] Furthermore, a cap position is provided at the top of the sample tube clamping position.

[0006] Furthermore, the alternating opening mechanism also includes a fixed base and a pressing detection mechanism. The rotary motor and the pressing detection mechanism are mounted on the fixed base. The pressing detection mechanism is set corresponding to the sample tube clamping position. When there is a sample tube in the sample tube clamping position, the pressing detection mechanism presses the sample tube in the sample tube clamping position.

[0007] Furthermore, the clamping detection mechanism includes a guide plate, a clamping component, a micro switch, a guide rod, and a push-pull electromagnet. The guide plate and the push-pull electromagnet are fixedly connected to the fixed base. The first side of the clamping component is slidably connected to the guide plate, and the second side of the clamping component is connected to the guide rod. The guide rod is arranged parallel to the guide plate and elastically connected to the push-pull electromagnet. The micro switch is located on the clamping component facing the sample tube clamping position. The micro switch can detect whether there is a sample tube in the sample tube clamping position. When there is a sample tube in the sample tube clamping position, the push-pull electromagnet magnetically attracts the micro switch to clamp the sample tube in the sample tube clamping position.

[0008] Furthermore, the clamping component has a slider on its first side, a horizontal slide rail and a stop block on the guide plate, the slider is slidably connected to the horizontal slide rail, the stop block limits the sliding stroke of the slider relative to the horizontal slide rail, and the horizontal slide rail is arranged parallel to the guide rod.

[0009] Furthermore, the clamping component includes an arc-shaped groove, which is correspondingly arranged with the sample tube clamping position, and the micro switch is located at the bottom of the arc-shaped groove.

[0010] This application also provides an alternating cap opening and liquid dispensing structure, which includes the alternating cap opening mechanism described above.

[0011] Furthermore, the alternating cap-opening and liquid-taking structure also includes a rotating cap-opening robotic arm and a liquid-drawing robotic arm, which are respectively located on both sides of the rotary motor. When a sample tube is placed in the sample tube clamping position of the rotating bracket corresponding to the rotating cap-opening robotic arm, the rotating cap-opening robotic arm opens the cap of the sample tube, and the rotary motor rotates one revolution to rotate the capped sample tube to below the liquid-drawing robotic arm. The liquid-drawing robotic arm then draws liquid from the sample tube or injects liquid into the sample tube.

[0012] Furthermore, the alternating cap opening and liquid extraction structure also includes an operating platform and a sliding mechanism. The alternating cap opening mechanism and the sliding mechanism are arranged on the operating platform. The rotating cap opening robotic arm and the liquid extraction robotic arm are arranged on the sliding mechanism and are located above the alternating cap opening mechanism.

[0013] The alternating cap opening mechanism and alternating cap opening liquid extraction structure provided in this application embodiment include a rotary motor, a rotating bracket, and a position sensor. The rotating bracket is linear, and sample tube clamping positions are provided at both ends of the rotating bracket. The sample tube clamping positions at both ends of the rotating bracket can simultaneously clamp the sample tubes for cap opening and liquid extraction / injection operations. Processing reagents can be added or samples can be transferred to the constant temperature module simultaneously when the cap is unscrewed. The processing operation is highly continuous, improving work efficiency. Attached Figure Description

[0014] The technical solution and other beneficial effects of this application will become apparent from the following detailed description of specific embodiments in conjunction with the accompanying drawings.

[0015] Figure 1 This is a schematic diagram of the alternating lid opening mechanism provided in an embodiment of this application;

[0016] Figure 2 This is a schematic diagram of the compression detection mechanism provided in the embodiments of this application;

[0017] Figure 3 This is a schematic diagram of the structure for placing sample tubes using the alternating cap opening mechanism provided in an embodiment of this application;

[0018] Figure 4 This is a schematic diagram of the alternating opening and liquid dispensing structure provided in the embodiments of this application;

[0019] Figure 5 This is a schematic diagram of the structure of the rotating lid-opening robotic arm provided in the embodiments of this application;

[0020] Figure 6 This is a schematic diagram of the structure of the liquid extraction robotic arm provided in an embodiment of this application.

[0021] The markings in the diagram are as follows:

[0022] Sample tube 1, alternating cap opening mechanism 2, rotary motor 21, rotating shaft 211, rotating bracket 22, sample tube clamping position 221, cap position 222, position sensor 23, fixed base 24, clamping detection mechanism 25, guide plate 251, clamping component 252, micro switch 253, guide rod 254, push-pull electromagnet 255, slider 256, horizontal slide rail 257, stop block 258, arc groove 259, rotating cap opening robotic arm 3, bottle cap rotating gripper 31, liquid suction robotic arm 4, lifting liquid suction tube 41, operating table 5, sliding mechanism 6. Detailed Implementation

[0023] The technical solutions of the embodiments of this application will be clearly and completely described below with reference to the accompanying drawings. Obviously, the described embodiments are only a part of the embodiments of this application, and not all of them. All other embodiments obtained by those skilled in the art based on the embodiments of this application without creative effort are within the scope of protection of this application.

[0024] In the description of this application, it should be noted that, unless otherwise expressly specified and limited, the terms "installation," "connection," and "linking" should be interpreted broadly. For example, they can refer to a fixed connection, a detachable connection, or an integral connection; they can refer to a mechanical connection, an electrical connection, or a connection that allows communication between them; they can refer to a direct connection or an indirect connection through an intermediate medium; they can refer to the internal communication between two components or the interaction between two components. Those skilled in the art can understand the specific meaning of the above terms in this application according to the specific circumstances.

[0025] In this application, unless otherwise expressly specified and limited, "above" or "below" the second feature can include direct contact between the first and second features, or contact between the first and second features through another feature between them. Furthermore, "above," "over," and "on top" of the second feature includes the first feature being directly above or diagonally above the second feature, or simply indicates that the first feature is at a higher horizontal level than the second feature. "Below," "below," and "under" the second feature includes the first feature being directly below or diagonally below the second feature, or simply indicates that the first feature is at a lower horizontal level than the second feature.

[0026] like Figure 1 , Figure 2 , Figure 3 , Figure 4 As shown in the figure, this application embodiment provides an alternating cap opening mechanism 2, which includes a rotary motor 21, a rotating bracket 22, and a position sensor 23. The rotary motor 21 is provided with a rotating shaft 211, and the rotating bracket 22 is connected to the rotating shaft 211. The position sensor 23 is fixed on the rotary motor 21 and disposed adjacent to the rotating shaft 211. The position sensor 23 detects the position of the rotating bracket 22. The rotating bracket 22 is linear, and sample tube clamping positions 221 are respectively provided at both ends of the rotating bracket 22. The position sensor 23 is electrically connected to the rotary motor 21. When the rotary motor 21 is turned on, the position sensor 23 controls the rotary motor 21 to stop when it detects the rotating bracket 22.

[0027] This configuration allows the detection signal from the position sensor 23 to control the rotating motor 21 to rotate the rotating bracket 22 by 180 degrees each time it starts, thus enabling the sample tube clamping positions 221 at both ends of the rotating bracket 22 to interchange positions.

[0028] Specifically, opening the cap and extracting / injecting liquid are performed on both sides of the straight line of the rotating bracket 22, so that the sample tube clamping positions 221 at both ends of the rotating bracket 22 can simultaneously clamp the sample tube 1 for opening the cap and extracting / injecting liquid. When the cap is unscrewed, the addition of processing reagents or the extraction and transfer of liquid to the constant temperature module can be performed simultaneously, resulting in strong continuity of processing operations and improved work efficiency.

[0029] like Figure 1 , Figure 3 As shown, the sample tube clamping position 221 has a cap position 222 at its top. A bottle cap unscrewed from the sample tube 1 can be placed in the cap position 222.

[0030] like Figure 1 , Figure 2 , Figure 3 As shown, the alternating opening mechanism 2 also includes a fixed base 24 and a pressing detection mechanism 25. The rotary motor 21 and the pressing detection mechanism 25 are mounted on the fixed base 24. The pressing detection mechanism 25 is set corresponding to the sample tube clamping position 221. When there is a sample tube 1 in the sample tube clamping position 221, the pressing detection mechanism 25 presses the sample tube 1 in the sample tube clamping position 221.

[0031] like Figure 1 , Figure 2 , Figure 3 As shown, the clamping detection mechanism 25 includes a guide plate 251, a clamping component 252, a micro switch 253, a guide rod 254, and a push-pull electromagnet 255. The guide plate 251 and the push-pull electromagnet 255 are fixedly connected to the fixed base 24. The first side of the clamping component 252 is slidably connected to the guide plate 251, and the second side of the clamping component 252 is connected to the guide rod 254. The guide rod 254 is arranged parallel to the guide plate 251 and is elastically connected to the push-pull electromagnet 255. The micro switch 253 is located on the clamping component 252 facing the sample tube clamping position 221. The micro switch 253 can detect whether there is a sample tube 1 in the sample tube clamping position 221. When there is a sample tube 1 in the sample tube clamping position 221, the push-pull electromagnet 255 magnetically attracts the micro switch 253 to clamp the sample tube 1 in the sample tube clamping position 221.

[0032] like Figure 1 , Figure 2 , Figure 3 As shown, the clamping component 252 has a slider 256 on its first side, and the guide plate 251 has a horizontal slide rail 257 and a stop block 258. The slider 256 is slidably connected to the horizontal slide rail 257, and the stop block 258 limits the sliding stroke of the slider 256 relative to the horizontal slide rail 257. The horizontal slide rail 257 is arranged parallel to the guide rod 254.

[0033] like Figure 1 , Figure 2 , Figure 3 As shown, the clamping component 252 includes an arc-shaped groove 259, which is correspondingly arranged with the sample tube clamping position 221, and the micro switch 253 is located at the bottom of the arc-shaped groove 259.

[0034] like Figure 4 As shown, this application also provides an alternating cap opening and liquid dispensing structure, which includes the alternating cap opening mechanism 2 described above.

[0035] like Figure 4 As shown, the alternating cap-opening liquid extraction structure also includes a rotating cap-opening robotic arm 3 and a liquid extraction robotic arm 4, which are respectively located on both sides of the rotary motor 21. When the rotating bracket 22 is positioned in the sample tube clamping position 221 of the rotating cap-opening robotic arm 3, the rotating cap-opening robotic arm 3 opens the cap of the sample tube 1. The rotary motor 21 rotates once to rotate the opened sample tube 1 to below the liquid extraction robotic arm 4, and the liquid extraction robotic arm 4 extracts liquid from the sample tube 1 or injects liquid into the sample tube 1.

[0036] Wherein, after the rotating bracket 22 stops rotating through the position sensor 23, the rotating opening robotic arm 3 and the liquid extraction robotic arm 4 are respectively located on both sides of the rotating bracket 22, and the rotating opening robotic arm 3 and the liquid extraction robotic arm 4 are located on the straight line of the rotating bracket 22.

[0037] like Figure 5 As shown, the rotating cap-opening robotic arm 3 is equipped with a cap-rotating gripper 31, which is used to clamp the cap of the sample tube 1 and rotate it to open the cap.

[0038] like Figure 6 As shown, the liquid extraction robotic arm 4 is equipped with a lifting suction tube 41, which is inserted into the sample tube 1 after the cap is opened, and is used to extract liquid from the sample tube 1 or inject liquid into the sample tube 1.

[0039] like Figure 4As shown, the alternating cap opening and liquid extraction structure also includes an operating platform 5 and a sliding mechanism 6. The alternating cap opening mechanism 2 and the sliding mechanism 6 are arranged on the operating platform 5. The rotating cap opening robotic arm 3 and the liquid extraction robotic arm 4 are arranged on the sliding mechanism 6. The rotating cap opening robotic arm 3 and the liquid extraction robotic arm 4 are located above the alternating cap opening mechanism 2.

[0040] The sample processing procedure is as follows: After the sample in sample tube 1 is rotated and mixed, the gripper of the rotating cap-opening robotic arm 3 moves sample tube 1 into sample tube clamping position 221. The push-pull electromagnet 255 drives the clamping component 252. During clamping, sample tube 1 touches the micro switch 253, which detects sample tube 1. The cap-rotating gripper 31 on the rotating cap-opening robotic arm 3 removes the cap and places the cap in the cap position 222 above the sample tube clamping position 221. The rotating support 22 rotates 180 degrees, and the same procedure is performed for the next sample tube. Simultaneously, on the other side of the rotating support 22, the lifting suction tube 41 of the liquid extraction robotic arm 4 adds treatment reagents to the liquid in sample tube 1 after cap removal or extracts the liquid after adding treatment reagents for antibody treatment and culture. The alternating cap-opening mechanism 2 improves the cap-opening efficiency and liquid extraction / injection efficiency, ensuring strong continuity of processing operations and improving work efficiency.

[0041] The alternating cap opening mechanism and alternating cap opening liquid extraction structure provided in this application embodiment include a rotary motor, a rotating bracket, and a position sensor. The rotating bracket is linear, and sample tube clamping positions are provided at both ends of the rotating bracket. The sample tube clamping positions at both ends of the rotating bracket can simultaneously clamp the sample tubes for cap opening and liquid extraction / injection operations. Processing reagents can be added or samples can be transferred to the constant temperature module simultaneously when the cap is unscrewed. The processing operation is highly continuous, improving work efficiency.

[0042] In the above embodiments, the descriptions of each embodiment have different focuses. For parts not described in detail in a certain embodiment, please refer to the relevant descriptions in other embodiments.

[0043] The alternating cap opening mechanism and alternating cap opening liquid dispensing structure provided in the embodiments of this application have been described in detail above. Specific examples have been used to illustrate the principles and implementation methods of this application. The description of the above embodiments is only for the purpose of helping to understand the technical solutions and core ideas of this application. Those skilled in the art should understand that they can still modify the technical solutions described in the foregoing embodiments or make equivalent substitutions for some of the technical features; and these modifications or substitutions do not cause the essence of the corresponding technical solutions to deviate from the scope of the technical solutions of the embodiments of this application.

Claims

1. An alternate uncovering mechanism characterized in that, The alternating opening mechanism includes a rotary motor, a rotating bracket, and a position sensor. The rotary motor has a rotating shaft, the rotating bracket is connected to the rotating shaft, and the position sensor is fixed on the rotary motor and located adjacent to the rotating shaft. The position sensor detects the position of the rotating bracket, which is linear and has sample tube clamping positions at both ends. The position sensor is electrically connected to the rotary motor. When the rotary motor is turned on, the position sensor controls the rotary motor to stop when it detects the rotating bracket.

2. The alternate uncovering mechanism according to claim 1, wherein The sample tube clamping position is provided with a tube cap position at the top.

3. The alternate uncovering mechanism according to claim 1, wherein The alternating opening mechanism also includes a fixed base and a pressing detection mechanism. The rotary motor and the pressing detection mechanism are mounted on the fixed base. The pressing detection mechanism is set corresponding to the sample tube clamping position. When there is a sample tube in the sample tube clamping position, the pressing detection mechanism presses the sample tube in the sample tube clamping position.

4. The alternate uncovering mechanism according to claim 3, wherein The clamping detection mechanism includes a guide plate, a clamping component, a micro switch, a guide rod, and a push-pull electromagnet. The guide plate and the push-pull electromagnet are fixedly connected to the fixed base. The first side of the clamping component is slidably connected to the guide plate, and the second side of the clamping component is connected to the guide rod. The guide rod is arranged parallel to the guide plate and elastically connected to the push-pull electromagnet. The micro switch is located on the clamping component facing the sample tube clamping position. The micro switch can detect whether there is a sample tube in the sample tube clamping position. When there is a sample tube in the sample tube clamping position, the push-pull electromagnet magnetically attracts the micro switch to clamp the sample tube in the sample tube clamping position.

5. The alternate uncovering mechanism according to claim 4, wherein The clamping component has a slider on its first side, and the guide plate has a horizontal slide rail and a stop block. The slider is slidably connected to the horizontal slide rail, and the stop block limits the sliding stroke of the slider relative to the horizontal slide rail. The horizontal slide rail is arranged parallel to the guide rod.

6. The alternate uncovering mechanism according to claim 5, wherein The clamping component includes an arc-shaped groove, which is correspondingly arranged with the sample tube clamping position, and the micro switch is located at the bottom of the arc-shaped groove.

7. An alternating decap-pickup structure, characterized by comprising: The alternating cap opening liquid dispensing structure includes the alternating cap opening mechanism as described in any one of claims 1 to 6.

8. The alternating decap-filling structure of claim 7, wherein, The alternating cap opening and liquid extraction structure further includes a rotating cap opening robotic arm and a liquid extraction robotic arm, which are respectively located on both sides of the alternating cap opening mechanism. When a sample tube is placed in the sample tube clamping position of the rotating bracket corresponding to the rotating cap opening robotic arm, the rotating cap opening robotic arm opens the cap of the sample tube. The rotating motor rotates once to rotate the opened sample tube to below the liquid extraction robotic arm, and the liquid extraction robotic arm extracts liquid from the sample tube or injects liquid into the sample tube.

9. The alternating decap-filling structure of claim 8, wherein, The alternating cover opening and liquid taking structure further comprises an operation table and a sliding mechanism, the alternating cover opening mechanism and the sliding mechanism are arranged on the operation table, and the rotating cover opening mechanical arm and the liquid taking mechanical arm are arranged on the sliding mechanism and above the alternating cover opening mechanism.